README.md

metadata

license: cc-by-4.0
task_categories:
  - tabular-classification
  - regression
tags:
  - medical
  - oncology
  - synthetic-data
  - genomics
  - ehr
  - nsclc
  - bioinformatics
pretty_name: ANODE Synthetic Oncology & Genomics

ANODE: Synthetic NSCLC EHR & Genomics Dataset

Title: ANODE-OncoGen High-Fidelity Synthetic Records

This dataset consists of a high-density .jsonl collection of synthetic patient records for Non-Small Cell Lung Cancer (NSCLC), integrating clinical history with deep genomic markers.

📋 Full Feature Specifications

The dataset includes the following features for every patient record:

1. Administrative & Metadata

• patient_id: Unique identifier for the synthetic patient (e.g., ANODE_551499).
• record_id: Unique identifier for the specific clinical event.
• record_generation_timestamp: ISO 8601 timestamp of data simulation.
• synthetic_source: Versioning information for the Grok-4 high-fidelity simulator.

2. Clinical Demographics

• age_at_diagnosis: Patient age in years.
• sex: Biological sex (male/female).
• smoking_pack_years: Quantitative history of tobacco use.
• ecog_performance_status: Functional status score (0–4) indicating the patient's level of self-care.

3. Oncology & Histology

• cancer_type: Specific malignancy (Non-small cell lung cancer).
• histology: Cellular classification (e.g., Adenocarcinoma, Squamous cell carcinoma).
• stage_at_diagnosis: Disease progression stage (e.g., IVA, IVB).
• primary_tumor_size_cm: Diameter of the primary lesion in centimeters.
• metastatic_sites_count: Numerical count of secondary tumor locations.

4. Genomic & Biomarker Profile

• driver_mutation: Identified genetic drivers (e.g., ALK fusion, EGFR, KRAS, BRAF, or None).
• pd_l1_tps_percent: Tumor Proportion Score for PD-L1 expression (0–100%).
• tmb_mutations_per_mb: Tumor Mutational Burden measured in mutations per megabase.
• msi_status: Microsatellite instability status (e.g., MSS).

5. Treatment & Survival Outcomes

• first_line_regimen: Initial therapy used (e.g., carboplatin + paclitaxel + pembrolizumab).
• overall_survival_months: Time elapsed from diagnosis to death or last follow-up.
• censored: Boolean flag (true/false) indicating if the patient was still alive at the end of the simulation period.

📂 Technical Format

• File Extension: .jsonl (JSON Lines)
• Encoding: UTF-8
• Schema Consistency: Strict key-value pairing across all entries for programmatic parsing.