| | --- |
| | license: cc-by-4.0 |
| | task_categories: |
| | - tabular-classification |
| | - regression |
| | tags: |
| | - medical |
| | - oncology |
| | - synthetic-data |
| | - genomics |
| | - ehr |
| | - nsclc |
| | - bioinformatics |
| | pretty_name: ANODE Synthetic Oncology & Genomics |
| | --- |
| | |
| | # ANODE: Synthetic NSCLC EHR & Genomics Dataset |
| |
|
| | ## Title: ANODE-OncoGen High-Fidelity Synthetic Records |
| |
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| | This dataset consists of a high-density `.jsonl` collection of synthetic patient records for Non-Small Cell Lung Cancer (NSCLC), integrating clinical history with deep genomic markers. |
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| | ### 📋 Full Feature Specifications |
| | The dataset includes the following features for every patient record: |
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|
| | #### 1. Administrative & Metadata |
| | * **patient_id**: Unique identifier for the synthetic patient (e.g., `ANODE_551499`). |
| | * **record_id**: Unique identifier for the specific clinical event. |
| | * **record_generation_timestamp**: ISO 8601 timestamp of data simulation. |
| | * **synthetic_source**: Versioning information for the Grok-4 high-fidelity simulator. |
| | |
| | #### 2. Clinical Demographics |
| | * **age_at_diagnosis**: Patient age in years. |
| | * **sex**: Biological sex (male/female). |
| | * **smoking_pack_years**: Quantitative history of tobacco use. |
| | * **ecog_performance_status**: Functional status score (0–4) indicating the patient's level of self-care. |
| | |
| | #### 3. Oncology & Histology |
| | * **cancer_type**: Specific malignancy (Non-small cell lung cancer). |
| | * **histology**: Cellular classification (e.g., Adenocarcinoma, Squamous cell carcinoma). |
| | * **stage_at_diagnosis**: Disease progression stage (e.g., IVA, IVB). |
| | * **primary_tumor_size_cm**: Diameter of the primary lesion in centimeters. |
| | * **metastatic_sites_count**: Numerical count of secondary tumor locations. |
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| | |
| | #### 4. Genomic & Biomarker Profile |
| | * **driver_mutation**: Identified genetic drivers (e.g., ALK fusion, EGFR, KRAS, BRAF, or None). |
| | * **pd_l1_tps_percent**: Tumor Proportion Score for PD-L1 expression (0–100%). |
| | * **tmb_mutations_per_mb**: Tumor Mutational Burden measured in mutations per megabase. |
| | * **msi_status**: Microsatellite instability status (e.g., MSS). |
| | |
| | #### 5. Treatment & Survival Outcomes |
| | * **first_line_regimen**: Initial therapy used (e.g., carboplatin + paclitaxel + pembrolizumab). |
| | * **overall_survival_months**: Time elapsed from diagnosis to death or last follow-up. |
| | * **censored**: Boolean flag (true/false) indicating if the patient was still alive at the end of the simulation period. |
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| | |
| | ### 📂 Technical Format |
| | * **File Extension**: `.jsonl` (JSON Lines) |
| | * **Encoding**: UTF-8 |
| | * **Schema Consistency**: Strict key-value pairing across all entries for programmatic parsing. |
| | * |
