sent1 stringlengths 15 4.99k | sent2 stringlengths 14 5.05k | labels int64 0 1 |
|---|---|---|
It (or homoorientin) is a flavone, a chemical flavonoid-like compound. It is the luteolin-6-C-glucoside. Bioassay-directed fractionation techniques led to isolation of isoorientin as the main hypoglycaemic component in Gentiana olivieri. Studies also showed that isoorientin is a potential neuroprotective compound again... | It is an organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, a... | 0 |
It is an ethyl sulfide compound having two ethyl groups attached to a sulfur atom. | It is a dibenzopyran. | 0 |
It is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is functionally related to a 2-tert-butylpyrimidin-5-ol. | It is a berberine alkaloid that is 5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline substituted by methoxy groups at positions 9 and 10. It is a berberine alkaloid, an organic heteropentacyclic compound, an aromatic ether and an oxacycle. | 0 |
The bromate anion, BrO, is a bromine-based oxoanion. A bromate is a chemical compound that contains this ion. Examples of bromates include sodium bromate, (), and potassium bromate, ().
Its are formed many different ways in municipal drinking water. The most common is the reaction of ozone and bromide:
: Br + → BrO
El... | It is a bromine oxoanion and a monovalent inorganic anion. It is a conjugate base of a bromic acid. | 1 |
It is polyphenol flavonoid from black tea (Camellia sinensis) created during fermentation, by oxidation of epigallocatechin gallate.
Its atropisomer is theasinensin D. | It is an organic compound with the formula that is used as a plant growth regulator. It is typically sold as the chloride salt, chlormequat chloride (CHClN), a colorless hygroscopic crystalline substance that is soluble in water and ethanol. It is an alkylating agent and a quaternary ammonium salt. It is one of the on... | 0 |
It (INN and BAN) or ticrynafen (USAN) is a loop diuretic drug with uric acid-lowering (uricosuric) action, formerly marketed for the treatment of hypertension. It was approved by FDA on May 2, 1979, and withdrawn in 1982, after case reports in the United States indicated a link between the use of ticrynafen and hepatit... | It is an aromatic ketone that is 2,3-dichlorophenoxyacetic acid in which the hydrogen at position 4 on the benzene ring is replaced by a thiophenecarbonyl group. A loop diuretic used to treat hypertension, it was withdrawn from the market in 1982 due to links with hepatitis. It has a role as a loop diuretic, an antihyp... | 1 |
It, sold under the brand name Inderal among others, is a medication of the beta blocker class. It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors, as well to prevent migraine headaches, and to prevent furt... | It is a propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3. It has a role as a beta-adrenergic antagonist, an anxiolytic drug, an anti-arrhythmia drug, a vasodilator agent, an antihypertensive agent, a xenobiotic, an environmental contami... | 1 |
It (PBO) is a pale yellow to light brown liquid organic compound used as an adjuvant component of pesticide formulations for synergy. That is, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone.
It is a semisyntheti... | It is an organic nitrate with vasodilator activity that is used to prevent or ameliorate attacks of angina pectoris. It dilates the coronary vessels because of its basic action as a smooth muscle depressant, just as do nitroglycerin and other organic nitrates. | 0 |
It is a semi-synthetic second-generation cephamycin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl, methoxy and {[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino groups at the 3, 7alpha, and 7beta positions, respectively, of the cephem skeleton. It is resistant to a wide range of be... | It is a quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. It has a role as an antiinfective agent, a topoisomerase IV inhibitor, an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor... | 0 |
It is a trihalomethane with formula .
It has formerly been used as a flame retardant, and a solvent for fats and waxes and because of its high density for mineral separation. Now it is only used as a reagent or intermediate in organic chemistry.
It can also occur in municipally-treated drinking water as a by-product of... | It is an antipsychotic drug of the phenothiazines class. It was synthesized by Wilhelm Schuler and colleagues at Degussa. In 1966, it was released in Belgium under the brand name Pasaden. At some point, it was quietly discontinued and is no longer marketed. | 0 |
It is an N-glycosyl compound consisting of a heteropolycyclic ring system with a glucosyl group attached to one of the indolic nitrogens. It is a N-glycosyl compound, an indolocarbazole, an organochlorine compound and an organic heterohexacyclic compound. | It is a tertiary alcohol. | 0 |
It is an unstable glucoside found in plants of the buttercup family (Ranunculaceae). On maceration, for example when the plant is wounded, it is enzymatically broken down into glucose and the toxin protoanemonin. | It is an alkaloid. | 0 |
It is an organochlorine pesticide having a 3,6-dichlorinated 4-aminopicolinic acid structure. It has a role as a herbicide. It is an organochlorine pesticide, a member of pyridines and an aromatic amine. It is functionally related to a picolinic acid. | It is a tropane alkaloid that consists of tropane bearing carboxy and hydroxy substituents at positions 2 and 3 respectively and having (1R,2R,3S,5S)-configuration. It is both a metabolite of and a precursor to cocaine. It has a role as a metabolite and a mouse metabolite. It is a tropane alkaloid and a 2-hydroxy monoc... | 0 |
It is a natural monoterpene ketone which is a component of some essential oils. Both stereoisomers, the -form and the -form, are known. The -form has a peppermint-like aroma and has been isolated from the oils of plants from the genera Cymbopogon, Andropogon, and Mentha. The -form has been isolated from Sitka spruce.... | It is an intermediate in cysteine metabolism. It has been studied as a potential treatment for cyanide poisoning, but its half-life is too short for it to be clinically effective. Instead, prodrugs, such as sulfanegen, are being evaluated to compensate for the short half-life of 3-mercaptopyruvic acid. | 0 |
It is a natural product found in Carica papaya and Xenorhabdus nematophila with data available. | It is a member of quinolines. | 0 |
It is a corticosteroid hormone. | It is a zwitterionic alkaloid and analog of psilocybin. It is found as a minor compound in most psilocybin mushrooms together with psilocybin, norbaeocystin, aeruginascin, and psilocin. It is an N-demethylated derivative of psilocybin, and a phosphorylated derivative of 4-HO-NMT (4-hydroxy-N-methyltryptamine). The st... | 0 |
It (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B, is a coenzyme in a variety of enzymatic reactions. The International Union of Biochemistry and Molecular Biology has catalogued more than 140 PLP-dependent activities, corresponding to ~4% of all classified activities. The versatility of PLP arises fr... | It is an N-sulfonylurea that is N-carbamoyl-2-chlorobenzenesulfonamide in which one of the hydrogens attached to the non-sulfonylated nitrogen has been replaced by a 4-methoxy-6-methyl-1,3,5-triazin-2-yl group. A herbicide used for the control of broadleaf weeds in wheat, barley and oats. It has a role as an agrochemic... | 0 |
It, is an organic compound with the molecular formula (CHCO)O. This colorless solid is the acid anhydride of succinic acid. | It is a natural product found in Medicago sativa with data available. | 0 |
It is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol. It has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections. It has a role as a plant metabolite, a solvent, a fuel additive, an adjuvant, a food additive... | It is a natural product found in Senegalia berlandieri with data available. | 0 |
It is an arsine oxide derived from phenylarsine. It has a role as an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, an apoptosis inducer and an antineoplastic agent. | It is an olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. It has a role as an antineoplastic agent, a carcinogenic agent, a xenoestrogen, an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor, an antifungal agent, an endocrine disruptor... | 0 |
It is an alkenyl phosphate that is the 2,2-dichloroethenyl ester of dimethyl phosphate. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an anthelminthic drug, an EC 3.1.1.8 (cholinesterase) inhibitor, an antibacterial agent and an antifungal agent. It is an alkenyl phosphate, a dialkyl phosphate, an or... | L-leucine is the L-enantiomer of leucine. It has a role as a plant metabolite, an Escherichia coli metabolite, a Saccharomyces cerevisiae metabolite, a human metabolite, an algal metabolite and a mouse metabolite. It is a pyruvate family amino acid, a proteinogenic amino acid, a leucine and a L-alpha-amino acid. It is ... | 0 |
It is a natural product found in Camellia sinensis with data available. | It is a natural product found in Hydrangea serrata and Hydrangea macrophylla with data available. | 0 |
It is a natural product found in Chrysanthemum indicum with data available. | It is a benzoate ester. | 0 |
It (or oxyphenisatin) is a laxative. It is closely related to bisacodyl, sodium picosulfate, and phenolphthalein. Long-term use is associated with liver damage, and as a result, it was withdrawn in most countries in the early 1970s. The acetate derivative oxyphenisatine acetate was also once used as a laxative.
Natu... | It is a 7-O-glycoside of the flavanone eriodictyol and the disaccharide neohesperidose (α--rhamnopyranosyl-(1→2)-β--glucopyranose).
Note that the neo in the name in this case does not refer to the position of the B-ring (which is not in a neo position), but refer to the glycosyl moiety. | 0 |
It is a member of the class of ethanolamines that is ethanolamine having a N-hydroxyethyl substituent. It has a role as a human xenobiotic metabolite. It is functionally related to an ethanolamine. | It is a natural product found in Streptomyces canus with data available. | 0 |
It is an aromatic ketone that is cyclohexa-1,3-dione in which one of the hydrogens at position 2 is substituted by a 4-(methanesulfonyl)-2-nitrobenzoyl group. It has a role as a herbicide, an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor, a xenobiotic, an environmental contaminant and a carotenoid biosy... | It is a natural product found in Streptomyces sparsogenes with data available. | 0 |
It is a member of morpholines. | It is a member of the class of ethylenediamine derivatives that is ethylenediamine in which one of the nitrogens is substituted by two methyl groups, and the other nitrogen is substituted by a 2-pyridyl group and a (2-thienyl)methyl group. It has a role as a H1-receptor antagonist, an anti-allergic agent, a sedative an... | 0 |
It usually refers to the inorganic compound with the formula NaAsO. Also called sodium meta-arsenite, it is the sodium salt of arsenous acid. Sodium ortho-arsenite is NaAsO. The compounds are colourless solids. | L-dehydroascorbic acid is dehydroascorbic acid having the L-configuration. It has a role as a coenzyme and a mouse metabolite. It is a vitamin C and a dehydroascorbic acid. It is functionally related to a L-ascorbic acid. It is a conjugate acid of a L-dehydroascorbate. | 0 |
It is a selenoamino acid that is the selenium analogue of methionine. It has a role as a plant metabolite. It is a member of selenomethionines and a selenoamino acid. | Acene is a polycyclic aromatic hydrocarbon consisting of fused benzene rings in a rectilinear arrangement. It is an ortho-fused polycyclic arene and a member of acenes. | 0 |
It is a pyruvate ester resultinf grom the formal condensation of the carboxy group of pyruvic acid with the hydroxy group of methanol. It is a pyruvate ester and a methyl ester. It is functionally related to a pyruvic acid. | It is a fungicide, a member benzimidazole fungicides. It is a metabolite of benomyl.
The fungicide is used to control plant diseases in cereals and fruits, including citrus, bananas, strawberries, macadamia nuts, pineapples, and pomes. A 4.7% solution of carbendazim hydrochloride, sold as Eertavas, is marketed as a tr... | 0 |
It is a primary amino compound obtained by formal decarboxylation of the amino acid tyrosine. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor, a human metabolite, an Escherichia coli metabolite, a mouse metabolite and a neurotransmitter. It is a monoamine molecular messenger, a primary amino compound and a me... | It is an antibiotic that has been in use in Europe for about fifty years, and has proven to be very effective at combating biofilm infections. It was shown to cause a decrease in the biofilm density of P. aeruginosa infections, which would allow access to the infection by the immune system in vivo. It was shown that n... | 0 |
It is a member of the class of pyrroles carrying chloro and 3-chloro-2-nitrophenyl substituents at positions 3 and 4 respectively. It has a role as a bacterial metabolite and an antifungal drug. It is a member of pyrroles, a member of monochlorobenzenes, a C-nitro compound and an alkaloid. | It (PRN) is a phenylpyrrole chemical used an antifungal antibiotic. Pseudomonas pyrrocinia and other Pseudomonas species produce pyrrolnitrin from tryptophan as secondary metabolite. It is believed that the antifungal properties come from inhibition of electron transport system.
The synthetic fungicides fenpiclonil and... | 1 |
It is an organic compound with the formula . It is one of three isomeric cyclohexanediones. It is a colorless compound that is soluble in a variety of organic solvents. It can be prepared by oxidation of cyclohexanone by selenium dioxide. The enol is about 1 kcal/mol more stable than the diketo form.
Numerous diimi... | Its are chemical compounds which include the fulminate ion (). The fulminate ion is a pseudohalic ion because its charge and reactivity are similar to those of the halogens. Due to the instability of the ion, fulminate salts are friction-sensitive explosives. The best known is mercury(II) fulminate, which has been used... | 0 |
It is a drug that possesses sedative and anxiolytic properties. Marketed as Tacitin by Ciba-Geigy, it is different from most sedative drugs because in most clinical trials it does not produce respiratory depression, but actually stimulates the respiratory system. As a result, when compared to other sedative and anxioly... | 4-nitrophenol is a member of the class of 4-nitrophenols that is phenol in which the hydrogen that is para to the hydroxy group has been replaced by a nitro group. It has a role as a human xenobiotic metabolite and a mouse metabolite. It is a conjugate acid of a 4-nitrophenolate. | 0 |
It and its precursor limonene are naturally occurring monocyclic terpenes derived from the mevalonate pathway in plants. It can be found in the essential oils of various plants, such as lavender, lemongrass, sage, and peppermint. It has a number of manufacturing, household, and medical applications. For example, perill... | It mesylate (Tornalate) is a short-acting β adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and COPD. In these disorders there is a narrowing of the airways (bronchi and their ramifications) that carry air to the lungs. Muscle spasm and inflammation within the bronchi worse... | 0 |
It is an organic compound with the formula CHN. It is an aromatic heterocycle with a bicyclic structure consisting of two fused six-membered aromatic rings, a benzene ring and a pyrimidine ring. It is a light yellow crystalline solid that is soluble in water. Also known as 1,3-diazanaphthalene, quinazoline received it... | It is a natural product found in Maerua subcordata with data available. | 0 |
3-hydroxy-3-methylglutaric acid is a dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-... | It is a diarylmethane. | 0 |
It is a member of the class of chromones that is chromone substituted by a hydroxy group at position 5, a methoxy group at position 7 and a methyl group at position 2. It has been isolated from Pisonia aculeata. It has a role as a plant metabolite. It is a member of chromones, a member of phenols and an aromatic ether.... | It (4-isopropylbenzaldehyde) is a natural organic compound with the molecular formula CHO. It is a benzaldehyde with an isopropyl group substituted in the 4-position.
It is a constituent of the essential oils of eucalyptus, myrrh, cassia, cumin, and others. It has a pleasant smell and contributes to the aroma of thes... | 0 |
It is a natural product found in Microchloropsis salina, Cladophora glomerata, and other organisms with data available. | It is a natural product found in Plumeria rubra, Streptomyces, and other organisms with data available. | 0 |
It is a member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug. It has a ro... | It is a lignan found in many plants of the family Asteraceae, particularly the greater burdock (Arctium lappa) and Centaurea imperialis, and in Trachelospermum asiaticum, Saussurea heteromalla, and Forsythia viridissima. It is the glucoside of arctigenin.
It and arctigenin have shown anticancer effects in animal resea... | 0 |
It is a 3-oxo Delta(4)-steroid that is estr-4-en-3-one substituted by a beta-hydroxy group at position 17. It has a role as a human metabolite. It is a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid and an anabolic androgenic steroid. It derives from a hydride of an estrane. | It is a pyranoindolizinoquinoline. | 0 |
It is the chemical compound with the formula SF. It is a colorless corrosive gas that releases dangerous HF upon exposure to water or moisture. Despite these unwelcome characteristics, this compound is a useful reagent for the preparation of organofluorine compounds, some of which are important in the pharmaceutical an... | It, also known as 3-hydroxybutanone or acetyl methyl carbinol, is an organic compound with the formula CHCH(OH)C(O)CH. It is a colorless liquid with a pleasant, buttery odor. It is chiral. The form produced by bacteria is (R)-acetoin. | 0 |
It is a natural product found in Camellia sinensis, Trigonella foenum-graecum, and other organisms with data available. | It is a natural product found in Veratrum dahuricum, Veratrum taliense, and other organisms with data available. | 0 |
It is a dicarboximide that is pyrrolidine which is substituted by oxo groups at positions 2 and 5. It is a pyrrolidinone and a dicarboximide. | It is a natural product found in Camellia sinensis, Raphanus sativus var. sativus, and other organisms with data available. | 0 |
It is an anthocyanidin cation consisting of benzopyrylium with hydroxy substituents at positions 3 and 7, a methoxy group at position 5 and a 4-hydroxy-3,5-dimethoxyphenyl group at position 2 respectively. It has a role as a plant metabolite. | It (Cp) is an O-methylated anthocyanidin. It is a water-soluble, blue-red plant dye. It is a 5-methoxy analog of malvidin, has been obtained from Plumbago capensis. | 1 |
It is an imidazoline compound having the double bond at the 2-position. | It, also known as isopentyl acetate, is an ester formed from isoamyl alcohol and acetic acid, with the molecular formula . It is a colorless liquid that is only slightly soluble in water, but very soluble in most organic solvents. It has a strong odor which is described as similar to both banana and pear. Pure isoamyl... | 0 |
It, sold under the brand name Zarontin among others, is a medication used to treat absence seizures. It may be used by itself or with other antiseizure medications such as valproic acid. It is taken by mouth.
It is usually well tolerated. Common side effects include loss of appetite, abdominal pain, diarrhea, and feeli... | It is a natural product found in Catalpa ovata, Plenckia populnea, and other organisms with data available. | 0 |
It (16-keto-E2, 16-oxoestradiol, or 16-oxo-E2) is an endogenous estrogen related to 16-ketoestrone. 16-Ketoestrone is a very weak estrogen with only 1/1000 the estrogenic potency of estradiol in the uterus. It is a so-called "short-acting" or "impeded" estrogen, similarly to estriol and dimethylstilbestrol. | It, or trichloromethane (often abbreviated as TCM), is an organic compound with the formula and a common solvent. It is a very volatile, colorless, strong-smelling, dense liquid produced on a large scale as a precursor to refrigerants and PTFE. It is a trihalomethane that serves as a powerful anesthetic, euphoriant, a... | 0 |
It is an imidazolidine-2,4-dione. | It is a steroid. It derives from a hydride of an estrane. | 0 |
It is a p-menthane monoterpenoid that is cyclohex-2-en-1-one substituted by a methyl group at position 3 and an isopropyl group at position 6. It has a role as a volatile oil component and a plant metabolite. It is a p-menthane monoterpenoid and a cyclic terpene ketone. | It is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.
In the United Kingdom, buclizine is one of three drugs contained in Migraleve tablets, marketed by McNeil Healthcare for migraines. | 0 |
It is an isoquinoline alkaloid. | It is a cholestanoid and a 3beta-sterol. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It derives from a hydride of a 5alpha-cholestane. | 0 |
It is a bicyclic sesquiterpene produced by certain fungi including the cheese mold Penicillium roqueforti. It is biosynthesized from farnesyl pyrophosphate by aristolochene synthase and is the parent hydrocarbon of a large variety of fungal toxins.
The substance was first isolated from Penicillium roqueforti, a fungus... | It is a chloroalkene. It has a role as an estrogen receptor modulator, an antineoplastic agent and a xenoestrogen. It derives from a hydride of a stilbene. | 0 |
It is a member of piperidines. | It is a monoterpenoid. | 0 |
It is a carboxylic ester resulting from the formal condensation of 3-methylflavone-8-carboxylic acid with 2-(1-piperidinyl)ethanol. It has a role as a parasympatholytic, a muscarinic antagonist and an antispasmodic drug. It is a member of piperidines, a member of flavones, a carboxylic ester and a tertiary amino compou... | It is a 3-hydroxy steroid that is 5alpha-stigmastane which is substituted at the 3beta position by a hydroxy group. It has a role as an anticholesteremic drug and a plant metabolite. It is a 3-hydroxy steroid and a member of phytosterols. It derives from a hydride of a 5alpha-stigmastane. | 0 |
It (also known as 2-cystenyl-1,4-dihydroxycyclohexenylacetate) is an amino acid, which is formed after detoxification of a reactive tyrosine metabolite (quinol acetate) by glutathione. It is ninhydrin positive (a common test to detect amino acids and proteins with a free -NH group).
It is found in elevated concentratio... | It is propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs. It has a role as a non-steroidal anti-inflammatory drug, an EC 1.... | 0 |
It is a natural product found in Phomopsis phaseoli with data available. | It is a member of imidazolidines. | 0 |
It is an alkane. | O-orsellinate depside is a benzoate ester. It is functionally related to an o-orsellinic acid. It is a conjugate acid of an o-orsellinate depsidate(1-). | 0 |
It is a bromoalkane that is ethane carrying a bromo substituent. It is an alkylating agent used as a chemical intermediate in various organic syntheses. It has a role as a carcinogenic agent, a solvent, a refrigerant, a local anaesthetic and an alkylating agent. It is a bromoalkane, a bromohydrocarbon and a volatile or... | It ( or , from Ancient Greek ξανθός xanthós "yellow" due to its yellowish-white appearance; archaically xanthic acid; systematic name 3,7-dihydropurine-2,6-dione) is a purine base found in most human body tissues and fluids, as well as in other organisms. Several stimulants are derived from xanthine, including caffeine... | 0 |
It is a benzazepine. | It is a member of imidazoles. It has a role as an anticoronaviral agent. | 0 |
It is a member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspen... | It is a 1-benzopyran. | 0 |
It is an antibiotic used to treat protozoan infections. A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction between 2-methyl-5-nitroimidazole and epichlorohydrin.
Antimicrobial spectrum is similar to that of metronidazole and is more well tolerated; however there are concerns of low... | It is an inorganic chloride salt with formula SbCl3. It is used as a reagent for detecting vitamin A and related carotenoids, reacting with the carotenoid to form a blue complex that can be measured by colorimetry (the Carr-Price test). Solutions of antimony trichloride were formerly used for dissolving and removing ho... | 0 |
It is a uricosuric agent and non-competitive inhibitor of xanthine oxidase used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects. It is structurally related to the antiarrhythmic amiodarone.
It is highly effective and well tolerated, and clinic... | (3R,4R,5R)-5-[(1R)-1,2-bis(phenylmethoxy)ethyl]-2-ethoxy-4-phenylmethoxy-3-oxolanol is a glycoside. | 0 |
3-hydroxypicolinic acid is a monohydroxypyridine that is picolinic acid in which the hydrogen at position 3 is replaced by a hydroxy group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of oligonucleotides. It has a role as a MALDI matrix material. It i... | It is an organic compound with the formula (CHCH)NH. It is a secondary amine. It is a flammable, weakly alkaline liquid that is miscible with most solvents. It is a colorless liquid, but commercial samples often appear brown due to impurities. It has a strong ammonia-like odor. | 0 |
It is a member of the class of triazoles that is 5-oxo-1,2,4-triazole which is substituted at positions 1, 3, and 4 by 2,4-dichloro-5-[(methylsulfonyl)amino]phenyl, methyl, and difluoromethyl groups, respectively. A protoporphyrinogen oxidase inhibitor, it is used as a herbicide to control broad-leaved weeds in soya an... | It (symbol Val or V) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO form under biological conditions), and a side chain isopropyl group, making ... | 0 |
It is a natural product found in Ophioparma ventosa with data available. | It is an aromatic ketone. | 0 |
It is an antibiotic drug of the penicillin class. It is a produg of ampicillin; after oral administration of lenampicillin, ampicillin is rapidly formed.
It inhibits bacterial penicillin binding proteins (transpeptidase) and is effective against a wide range of bacterial infections.
It was developed in Japan and has b... | It is a C21-steroid that is pregn-4-ene substituted by oxo groups at position 3 and 20 and hydroxy groups at positions 16 and 17. It has a role as a progestin. It is a 20-oxo steroid, a 16alpha-hydroxy steroid, a 17-hydroxy steroid, a C21-steroid, a 3-oxo-Delta(4) steroid and a tertiary alpha-hydroxy ketone. It derives... | 0 |
It is a quinolone antibiotic and a fluoroquinolone antibiotic. | It, sold under the brand names Nilandron and Anandron, is a nonsteroidal antiandrogen (NSAA) which is used in the treatment of prostate cancer. It has also been studied as a component of feminizing hormone therapy for transgender women and to treat acne and seborrhea in women. It is taken by mouth.
Side effects in men ... | 0 |
It is a purine nucleoside in which xanthine is attached to ribofuranose via a beta-N(9)-glycosidic bond. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of xanthosines and a purines D-ribonucleoside. | It is an alpha-bromoketone that is acetone in which one of the hydrogens is replaced by a bromine atom. A poweful lachrymator, it was formerly used as a chemical weapon. It has a role as a lachrymator. It is functionally related to an acetone. | 0 |
It is a bromine oxoacid. It is a conjugate acid of a perbromate. | It, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid use disorder. It is used to treat chronic pain, and it is also used to treat addiction to heroin or other opioids. Prescribed for daily use, the medicine relieves cravings and rem... | 0 |
It is a gamma-lactone. | It is an amino cyclitol glycoside that is isolated from Streptomyces kasugaensis and exhibits antibiotic and fungicidal properties. It has a role as a bacterial metabolite, a protein synthesis inhibitor and an antifungal agrochemical. It is an amino cyclitol glycoside, an aminoglycoside antibiotic, a monosaccharide der... | 0 |
It is a member of piperidines. It has a role as a glioma-associated oncogene inhibitor. | It is a quinolizidine alkaloid. | 0 |
It is an organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disord... | It is a sulfoxide that is the S-oxide of biotin. It has a role as a metabolite. It is a member of biotins and a sulfoxide. It is a conjugate acid of a biotinate sulfoxide(1-). | 0 |
It, more commonly known as its anionic form chorismate, is an important biochemical intermediate in plants and microorganisms. It is a precursor for:
* The aromatic amino acids phenylalanine, tryptophan, and tyrosine
* Indole, indole derivatives and tryptophan
* 2,3-Dihydroxybenzoic acid (DHB) used for enterobactin bio... | It is a natural product found in Artemia salina, Crotalaria prolongata, and Theobroma cacao with data available. | 0 |
It (; systematic name 4-β--glucan 4-glucanohydrolase) is any of several enzymes produced chiefly by fungi, bacteria, and protozoans that catalyze cellulolysis, the decomposition of cellulose and of some related polysaccharides:
: Endohydrolysis of (1→4)-β--glucosidic linkages in cellulose, lichenin and cereal β--glucan... | It is a sulfoxide and a member of pyrazolidines. It has a role as a uricosuric drug. | 0 |
It is a member of the class of cyclopentapyridines that is 6,7-dihydrocyclopenta[c]pyridine bearing two methyl substituents at positions 4 and 7. It has a role as a plant metabolite and a pheromone. It is a cyclopentapyridine and a pyridine alkaloid. | It is a member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as... | 0 |
It is a chemical compound with the molecular formula CHNO. It is an intermediate in the production of the biological pigment eumelanin. It is biosynthesized from -dopachrome in a reaction catalyzed by a tyrosinase enzyme and is further converted into indole-5,6-quinone. In humans, 5,6-dihydroxyindole is involved in ... | It is a 1,2-dithiole that is 3H-1,2-dithiole-3-thione substituted at positions 4 and 5 by methyl and pyrazin-2-yl groups respectively. It has a role as an antineoplastic agent, an antimutagen, a protective agent, an antioxidant, an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, a schistosomicide drug, a neurotox... | 0 |
It is a macrolide antibiotic. It is synthesized from strains of Streptomyces antibioticus. It is weaker than erythromycin.
It used to be sold under the brand name Sigmamycine, combined with tetracycline, and made by the company Rosa-Phytopharma in France. | It is a bromine oxoacid. It is a conjugate acid of a bromate. | 0 |
It, sold under the brand names Enovid, Norinyl, and Ortho-Novum among others, is an estrogen medication which has been used in birth control pills, menopausal hormone therapy, and the treatment of menstrual disorders. It is formulated in combination with a progestin and is not available alone. It is taken by mouth.
Sid... | It is a methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal sid... | 0 |
It is a natural product found in Capsicum annuum var. annuum with data available. | It is a cephamycin antibiotic, usually grouped with the second-generation cephalosporins.
__TOC__ | 0 |
It is a fatty acid ethyl ester obtained by the formal condensation of hexanoic acid with ethanol. It has a role as a metabolite. It is a fatty acid ethyl ester and a hexanoate ester. | It is a natural product found in Camellia sinensis, Erythrophleum fordii, and other organisms with data available. | 0 |
It is an organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. It inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticu... | It is a mononuclear parent hydride and a tin hydride. | 0 |
It is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an acaricide and an agrochemical. It is functionally related to a 5-methoxy-1,3,4-thiadiazol-2(3H)-one. | It is a chemical compound. It is the backbone of all flavonols, a type of flavonoid. It is a synthetic compound, which is not found naturally in plants. It serves as a model molecule as it possesses an excited-state intramolecular proton transfer (ESIPT) effect to serve as a fluorescent probe to study membranes for exa... | 0 |
It is a quaternary ammonium ion. | It is an organoarsenic compound that is the main source of arsenic found in fish. It is the arsenic analog of trimethylglycine, commonly known as betaine. The biochemistry and its biosynthesis are similar to those of choline and betaine.
It is a common substance in marine biological systems and unlike many other organo... | 0 |
It is an alkaloid found in the bark of the New Zealand tree Laurelia novae-zelandiae ("Pukatea"), as well as some South American plants. An extract from pukatea is used in traditional Māori herbal medicine as an analgesic.
Bernard Cracroft Aston studied the physical and chemical characteristics of the compound, and pre... | It is a member of tryptamines. It has a role as a serotonergic agonist, a vasoconstrictor agent and an anti-inflammatory drug. It is functionally related to a N,N-dimethyltryptamine. | 0 |
It is a tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety. It has a role as a H1-receptor antagonist, a sedative, an antiemetic, a local anaesthetic, an antipruritic drug, an anti-allergic agent and an anticoronaviral ... | It (INN) is a diuretic, part of the class of low-ceiling sulfonamide diuretics. It is used primarily in the treatment of oedema and hypertension. | 0 |
It is an iridoid monoterpene. It is produced from 7-deoxyloganetic acid by the enzyme 7-deoxyloganetic acid glucosyltransferase (7-DLGT). The metabolite is a substrate for the enzyme 7-deoxyloganic acid hydroxylase (7-DLH) which synthesizes loganic acid. | It is an oxo carboxylic acid. | 0 |
It is a 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20. It has a role as a human metabolite and a mouse metabolite. It is a 20-oxo steroid, a C21-steroid and a 3beta-hydroxy-Delta(5)-steroid. It derives from a hydride of a pregnane. | It is a pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent. It has a role as an ionophore. It is a pyridinethione and a monohydroxypyridine. It is a tautomer ... | 0 |
It is a compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety. It has a role as a serotonergic antagonist, a first generation antipsychotic, a dopaminergic antagonist, an antidyskinesia agent and an antiemetic. It is a... | It is a monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor, an antipyretic, a xenobiotic, ... | 0 |
It is a sesquiterpenoid. | It is a member of phenothiazines. | 0 |
It, sold under the brand name Vepesid among others, is a chemotherapy medication used for the treatments of a number of types of cancer including testicular cancer, lung cancer, lymphoma, leukemia, neuroblastoma, and ovarian cancer. It is also used for hemophagocytic lymphohistiocytosis. It is used by mouth or injectio... | It is a N-acyl-amino acid. | 0 |
It is a high-affinity agonist ligand for the glucocorticoid receptor and consequently is classified as a glucocorticoid.
It is sometimes abbreviated "CVZ". | It is an organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-methylcyclohexyl group. It has a role as an antineoplastic agent, a carcinogenic agent and an alkylating age... | 0 |
It is a derivative of streptomycin that has a bactericidal properties. It is a semisynthetic aminoglycoside antibiotic used in the treatment of tuberculosis.
It acts by irreversibly binding the S12 protein in the bacterial 30S ribosomal subunit, after being actively transported across the cell membrane, which interfere... | It is a member of streptomycins. | 1 |
It is a capsaicinoid. | It (Tridione) is an oxazolidinedione anticonvulsant. It is most commonly used to treat epileptic conditions that are resistant to other treatments.
It is primarily effective in treating absence seizures, but can also be used in refractory temporal lobe epilepsy. It is usually administered 3 or 4 times daily, with the t... | 0 |
It is a phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group. It has a role as an intravenous anaesthetic, a sedative, a radical scavenger, an antiemetic and an anticonvulsant. | It is a saturated organic heteromonocyclic parent that is an analogue of morpholine where the oxygen atom is replaced by sulfur. It is a saturated organic heteromonocyclic parent and a member of thiomorpholines. | 0 |
It is a 17beta-hydroxy steroid that is estrane containing a double bond between positions 4 and 5 and substituted by an ethyl group and a hydroxy group at the 17alpha and 17beta positions, respectively. It is an anabolic steroid that has little androgenic effect and only slight progestational activity. It has been used... | It is an isothiocyanate. | 0 |
It is a choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. It has a role as a neurotransmitter, a nutrient, a human metabolite, a plant metabolite, a Daphnia magna metabolite, a Saccharomyces cerevisiae metabolite, an Es... | It is a natural product found in Echinopora lamellosa with data available. | 0 |
It is a natural product found in Apis cerana with data available. | It is an organic compound with the formula CHCOCH=CH. This colorless liquid is the precursor to polyvinyl acetate, ethene-vinyl acetate copolymers, polyvinyl alcohol, and other important industrial polymers. | 0 |
It or 1,3,5-trimethylbenzene is a derivative of benzene with three methyl substituents positioned symmetrically around the ring. The other two isomeric trimethylbenzenes are 1,2,4-trimethylbenzene (pseudocumene) and 1,2,3-trimethylbenzene (hemimellitene). All three compounds have the formula CH(CH), which is commonly a... | It is a natural product found in Angelica gigas, Rhodotorula mucilaginosa, and other organisms with data available. | 0 |
It is a piperidinemonocarboxylic acid that is (R)-nipecotic acid in which the hydrogen attached to the nitrogen has been replaced by a 1,1-bis(3-methyl-2-thienyl)but-1-en-4-yl group. A GABA reuptake inhibitor, it is used (generally as the hydrochloride salt) for the treatment of epilepsy. It has a role as a GABA reupta... | It (trade name Gabitril) is an anticonvulsant medication produced by Cephalon that is used in the treatment of epilepsy. The drug is also used off-label in the treatment of anxiety disorders and panic disorder. | 1 |
It is a dioxolane. | It is a monoterpenoid. | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.