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SBO is built in collaboration by the [http://www.ebi.ac.uk/compneur Computational Neurobiology Group] (Nicolas Le Novère, EMBL-EBI, United-Kingdom) and the SBMLTeam (Michael Hucka, Caltech, USA). | 1 | Biochemistry |
David G. Cory is a Professor of Chemistry at the University of Waterloo where he holds the Canada Excellence Research Chair in Quantum Information Processing. He works at the Institute for Quantum Computing, and is also associated with the Waterloo Institute for Nanotechnology. | 7 | Physical Chemistry |
Thomas Anderson (2 July 1819 – 2 November 1874) was a 19th-century Scottish chemist. In 1853 his work on alkaloids led him to discover the correct formula/composition for codeine. In 1868 he discovered pyridine and related organic compounds such as picoline through studies on the distillation of bone oil and oth... | 0 | Organic Chemistry |
:This type of reactor contains two banks of heat exchangers which remove heat; the remainder of which is removed by the products and recycled in the system. The formation of heavy waxes should be avoided, since they condense on the catalyst and form agglomerations. This leads to fluidization. Hence, risers are operated... | 0 | Organic Chemistry |
The statistical analysis of the large quantity of data generated from sequencing approaches is a challenge. Even by only sequencing the exomes of individuals, a large quantity of data and sequence information is generated which requires a significant amount of data analysis. Challenges associated with the analysis of t... | 1 | Biochemistry |
Immediately after his Ph.D, in 1980, René Roy joined the National Research Council (NRC) in Ottawa where he worked as researcher in the Institute for Biological Sciences. Then, in 1985, he began his career as professor in the department of chemistry of the University of Ottawa where he served until December 2002. In pa... | 0 | Organic Chemistry |
In hydroesterification, alkenes and alkynes insert into the bond of carboxylic acids. Vinyl acetate is produced industrially by the addition of acetic acid to acetylene in the presence of zinc acetate catalysts: Presently, zinc acetate is used as the catalyst:
Vinyl acetate can also be produced by palladium-catalyzed ... | 0 | Organic Chemistry |
In organic chemistry, hydroxamic acids are a class of organic compounds having a general formula bearing the functional group , where R and R' are typically organyl groups (e.g., alkyl or aryl) or hydrogen. They are amides () wherein the nitrogen atom has a hydroxyl () substituent. They are often used as metal chelato... | 0 | Organic Chemistry |
Polysulfides are a class of chemical compounds derived from anionic chains of sulfur atoms. There are two main classes of polysulfides: inorganic and organic. The inorganic polysulfides have the general formula . These anions are the conjugate bases of polysulfanes . Organic polysulfides generally have the formulae , w... | 8 | Metallurgy |
Temperature measurement (also known as thermometry) describes the process of measuring a current temperature for immediate or later evaluation. Datasets consisting of repeated standardized measurements can be used to assess temperature trends. | 7 | Physical Chemistry |
The Curiosity rover encountered rocks of special interest on the surface of Aeolis Palus near Aeolis Mons ("Mount Sharp") in Gale Crater. In the autumn of 2012, rocks studied, on the way from Bradbury Landing to Glenelg Intrigue, included "Coronation" rock (August 19, 2012), "Jake Matijevic" rock (September 19, 2012),... | 9 | Geochemistry |
The c-ANCA antigen is specifically proteinase 3 (PR3). p-ANCA antigens include myeloperoxidase (MPO) and bacterial permeability increasing factor Bactericidal/permeability-increasing protein (BPI). Other antigens exist for c-ANCA (atypical), however many are as yet unknown. Classical p-ANCA occurs with antibodies direc... | 1 | Biochemistry |
Frequent geometries considered involve the interaction between two identical spheres of radius R where the effective radius becomes
In the case of interaction between a sphere of radius R and a planar surface, one has
The above two relations can be obtained as special cases of the expression for R given further above. ... | 7 | Physical Chemistry |
In chemistry, the common-ion effect refers to the decrease in solubility of an ionic precipitate by the addition to the solution of a soluble compound with an ion in common with the precipitate. This behaviour is a consequence of Le Chatelier's principle for the equilibrium reaction of the ionic association/dissociatio... | 7 | Physical Chemistry |
An analyte, component (in clinical chemistry), titrand (in titrations), or chemical species is a substance or chemical constituent that is of interest in an analytical procedure. The purest substances are referred to as analytes, such as 24 karat gold, NaCl, water, etc. In reality, no substance has been found to be 100... | 3 | Analytical Chemistry |
Polyethylene may be considered either as -[CH-CH-]- with a repeat unit of -[CH-CH]-, or as [-CH-]-, with a repeat unit of -[CH]-. Chemists tend to consider the repeat unit as -[CH-CH]- since this polymer is made from the monomer ethylene (CH=CH).
More complex repeat units can occur in vinyl polymers -[CH-CHR]-, if one ... | 7 | Physical Chemistry |
Tamm et al. have shown that survivin inhibits both Bax and Fas-induced apoptotic pathways. The experiment involved transfecting HEK 293 cells with a Bax-encoding plasmid, which resulted in an increase in apoptosis (~7 fold) as measured by DAPI staining. They then contransfected the 293 cells with Bax-encoding plasmid a... | 1 | Biochemistry |
Of some interest in organic synthesis, electropositive metals react with many organic halides in a metal-halogen exchange:
The resulting organometallic compound is susceptible to hydrolysis:
Heavily studied examples are found in organolithium chemistry and organomagnesium chemistry. Some illustrative cases follow.
Lit... | 0 | Organic Chemistry |
To deal with decreased ATP production through the electron transport chain, fish must activate anaerobic means of energy production (see anaerobic metabolism) while suppressing metabolic demands. The ability to decrease energy demand by metabolic suppression is essential to ensure hypoxic survival due to the limited ef... | 9 | Geochemistry |
In the spinodal region of the phase diagram, the free energy can be lowered by allowing the components to separate, thus increasing the relative concentration of a component material in a particular region of the material. The concentration will continue to increase until the material reaches the stable part of the pha... | 7 | Physical Chemistry |
Because oxygen and argon leak through packaging material at different rates, comparing the ratios inside a package can determine if and how quickly air from outside has leaked in. | 3 | Analytical Chemistry |
In Egypt around 2000 BC, the juice of Ammi majus was rubbed on patches of vitiligo after which patients were encouraged to lie in the sun. In the 13th century, vitiligo was treated with a tincture of honey and the powdered seeds of a plant called "aatrillal", which was abundant in the Nile Valley. The plant has since b... | 5 | Photochemistry |
The development of the Isa Process tank house technology at CRL eliminated the whole process and cost of producing the starter sheets by using stainless-steel permanent cathodes. It also included substantial automation of the process of inserting the permanent cathodes into the electrolytic cells and their subsequent r... | 8 | Metallurgy |
Core-electron binding energy (CEBE) shifts correlate linearly with the Hammett substituent constants (σ) in substituted benzene derivatives.
Consider para-disubstituted benzene p-F-CH-Z, where Z is a substituent such as NH, NO, etc. The fluorine atom is para with respect to the substituent Z in the benzene ring. The im... | 7 | Physical Chemistry |
Heterolytic bond cleavage is a process where the electron pair that comprised a bond moves to one of the atoms that was formerly joined by a bond. The bond breaks, forming a negatively charged species (an anion) and a positively charged species (a cation). The anion is the species that retains the electrons from the ... | 0 | Organic Chemistry |
Swansea University has had a long established history of development and innovation in mass spectrometry and chromatography. | 3 | Analytical Chemistry |
In the secondary structure of proteins, hydrogen bonds form between the backbone oxygens and amide hydrogens. When the spacing of the amino acid residues participating in a hydrogen bond occurs regularly between positions i and , an alpha helix is formed. When the spacing is less, between positions i and , then a 3 hel... | 6 | Supramolecular Chemistry |
Presently known "super" states of matter are superconductors, superfluid liquids and gases, and supersolids. Egor Babaev predicted that if hydrogen and deuterium have liquid metallic states, they might have quantum ordered states that cannot be classified as superconducting or superfluid in the usual sense. Instead, th... | 7 | Physical Chemistry |
A glycosidic bond or glycosidic linkage is a type of ether bond that joins a carbohydrate (sugar) molecule to another group, which may or may not be another carbohydrate.
A glycosidic bond is formed between the hemiacetal or hemiketal group of a saccharide (or a molecule derived from a saccharide) and the hydroxyl grou... | 0 | Organic Chemistry |
Another proposal is that the dual-molecule system we see today, where a nucleotide-based molecule is needed to synthesize protein, and a peptide-based (protein) molecule is needed to make nucleic acid polymers, represents the original form of life. This theory is called RNA-peptide coevolution, or the Peptide-RNA world... | 9 | Geochemistry |
In organic chemistry, Möbius aromaticity is a special type of aromaticity believed to exist in a number of organic molecules. In terms of molecular orbital theory these compounds have in common a monocyclic array of molecular orbitals in which there is an odd number of out-of-phase overlaps, the opposite pattern compar... | 7 | Physical Chemistry |
Slayton A. Evans Jr. (May 17, 1943 – March 24, 2001) was an American chemist and professor at the University of North Carolina, Chapel Hill. He was a leading researcher into organophosphorus chemistry. His research led to a greater understanding of the functions of organophosphate compounds and innovations in methods t... | 4 | Stereochemistry |
The process in which amylase breaks down starch for sugar consumption is not consistent with all organisms that use amylase to breakdown stored starch. There are different amylase pathways that are involved in starch degradation. The occurrence of starch degradation into sugar by the enzyme amylase was most commonly kn... | 0 | Organic Chemistry |
Metal carbonyls are often characterized by C NMR spectroscopy. To improve the sensitivity of this technique, complexes are often enriched with CO. Typical chemical shift range for terminally bound ligands is 150 to 220 ppm. Bridging ligands resonate between 230 and 280 ppm. The C signals shift toward higher fields with... | 0 | Organic Chemistry |
The reason that Pseudomonas aeruginosa produces rhamnolipids is the subject of much speculation. They have been shown to have several properties, and investigations in a rhlA mutant that does not make HAAs nor rhamnolipids have attributed many functions to rhamnolipids which may in fact be due to HAAs. These functions ... | 0 | Organic Chemistry |
Once transported, the translated protein is 396 residues in length, with an N-terminus located at amino acids 1-25, a C-terminus at 155-396 (note that the spectrin homology located at 228-380 within the C-terminal), and a putative coiled coil domain at amino acids 26-154. Additionally, the protein has binding sites for... | 1 | Biochemistry |
Studies have shown that Zn, Pb, Cd, Sn and In can embrittle steel at temperature below each embrittler’s melting point.
*Cadmium can embrittle titanium at temperatures below its melting point.
*Hg can embrittle zinc at temperatures below its melting point.
*Hg can embrittle copper at temperatures below its melting poi... | 8 | Metallurgy |
HTK (branded as Custodiol® by Essential Pharmaceuticals LLC), has been presented by industry to surgeons as an alternative solution that exceeds other cardioplegias in myocardial protection during cardiac surgery. This claim relies on the single-dose administration of HTK compared with other multidose cardioplegias (MD... | 1 | Biochemistry |
Non-pathogenic species of the gram-positive Corynebacterium are used for the commercial production of various amino acids. The C. glutamicum species is widely used for producing glutamate and lysine, components of human food, animal feed and pharmaceutical products.
Expression of functionally active human epidermal gro... | 1 | Biochemistry |
When two lipid bilayers approach each other, they experience weak van der Waals attractive forces and much stronger repulsive forces due to hydration repulsion. These forces are normally dominant over the hydrophobic attractive forces between the membranes. Studies done on membrane bilayers using Surface forces apparat... | 6 | Supramolecular Chemistry |
Lichen associations may be examples of mutualism or commensalism, but the lichen relationship can be considered parasitic under circumstances where the photosynthetic partner can exist in nature independently of the fungal partner, but not vice versa. Photobiont cells are routinely destroyed in the course of nutrient e... | 2 | Environmental Chemistry |
Jun 1943. Further report on the use of aged chromate baths to specification DTD 911, Bath iii (30 minute hot chromate bath). Petch M K. RAE MR7147(A). Met/RTN/22
Feb 1944. Variations in corrosion properties over magnesium alloy sheet. Jones E R W Petch M K. RAE MR6858. Met/RTN/21, also in J. Inst. Metals, Nov. I946... | 8 | Metallurgy |
The most environmentally relevant species of these nanoparticles are silver chloride within marine ecosystems and organic thiols within terrestrial ecosystems. Once Ag enters the environment, it is oxidized to Ag. Of the potential species formed in seawater, such as AgS and AgCO, AgCl is the most thermodynamically favo... | 2 | Environmental Chemistry |
Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and m... | 0 | Organic Chemistry |
Electron-deficient olefins, such as enones and acryl derivatives can be epoxidized using nucleophilic oxygen compounds such as peroxides. The reaction is a two-step mechanism. First the oxygen performs a nucleophilic conjugate addition to give a stabilized carbanion. This carbanion then attacks the same oxygen atom, di... | 0 | Organic Chemistry |
Examples of amphiphilic compounds are the salts of fatty acids, phospholipids. Many simple amphiphiles are used as detergents. A mixture of soap and water is an everyday example of a lyotropic liquid crystal.
Biological structures such as fibrous proteins showings relatively long and well-defined hydrophobic and hydrop... | 7 | Physical Chemistry |
The four fundamental classes of forces and interaction in protein adsorption are: 1) ionic or electrostatic interaction, 2) hydrogen bonding, 3) hydrophobic interaction (largely entropically driven), and 4) interactions of charge-transfer or particle electron donor/acceptor type. | 1 | Biochemistry |
Salbutamol's low toxicity makes it safe for other animals and thus is the medication of choice for treating acute airway obstruction in most species. It is usually used to treat bronchospasm or coughs in cats and dogs and used as a bronchodilator in horses with recurrent airway obstruction; it can also be used in emerg... | 4 | Stereochemistry |
To carry out metal cation titrations using EDTA, it is almost always necessary to use a complexometric indicator to determine when the end point has been reached. Common indicators are organic dyes such as Fast Sulphon Black, Eriochrome Black T, Eriochrome Red B, Patton Reeder, or Murexide. Color change shows that th... | 3 | Analytical Chemistry |
If the two free ends of an ideal chain are pulled apart by some sort of device, then the device experiences a force exerted by the polymer. As the ideal chain is stretched, its energy remains constant, and its time-average, or internal energy, also remains constant, which means that this force necessarily stems from a ... | 7 | Physical Chemistry |
The release of neurotransmitter is accomplished by the fusion of neurotransmitter vesicles to the presynaptic membrane. Although the details of this mechanism are still being studied there is a consensus on some details of the process. Synaptic vesicle fusion with the presynaptic membrane is known to require a local ... | 1 | Biochemistry |
Large-scale oceanic circulation has a direct impact on opal deposition. The Pacific (characterized by nutrient poor surface waters, and deep nutrient rich waters) and Atlantic Ocean circulations favor the production/preservation of silica and carbonate respectively. For instance, Si/N and Si/P ratios increase from the ... | 1 | Biochemistry |
Zelinsky created a large scientific school and its scientists made fundamental contributions to various fields of chemistry. Among his students werw Academicians of the Academy of Sciences of the USSR A. A. Balandin, L. F. Vereshchagin, B. A. Kazansky, K. A. Kocheshkov, S. S. Nametkin, A. N. Nesmeyanov; Corresponding M... | 0 | Organic Chemistry |
Propionyl-CoA has can have many adverse and toxic affects on different species, including bacterium. For example, inhibition of pyruvate dehydrogenase by an accumulation of propionyl-CoA in Rhodobacter sphaeroides can prove deadly. Furthermore, as with E. coli, an influx of propionyl-CoA in Myobacterial species can res... | 1 | Biochemistry |
Yuan Chengye (; 1924–2018) was a Chinese organic chemist.
Yuan was born in Shangyu, Zhejiang province in 1924. He graduated from National College of Pharmacy (now China Pharmaceutical University) in 1948 and received Degree for Candidate for D.Sc from All-Union Research Institute of Pharmaceutical Chemistry, Moscow in ... | 0 | Organic Chemistry |
PCBs have low water solubility, so they adhere tightly to soil and cannot be easily accessed by bacteria. Especially, if the contaminations site has been exposed to PCBs for long period, PCBs can be integrated into soil or sediment matrices, then further decrease their bioavailability. Some surfactants can help solubil... | 1 | Biochemistry |
The inversion of ammonia was first detected by microwave spectroscopy in 1934.
In one study the inversion in an aziridine was slowed by a factor of 50 by placing the nitrogen atom in the vicinity of a phenolic alcohol group compared to the oxidized hydroquinone.
The system interconverts by oxidation by oxygen and reduc... | 4 | Stereochemistry |
Organic esters, ketones, and aldehydes with an α-hydrogen ( bond adjacent to the carbonyl group) often form enols. The reaction involves migration of a proton () from carbon to oxygen:
In the case of ketones, the conversion is called a keto-enol tautomerism, although this name is often more generally applied to all suc... | 0 | Organic Chemistry |
PDE3 enzymes are involved in regulation of cardiac and vascular smooth muscle contractility. Molecules that inhibit PDE3 were originally investigated for the treatment of heart failure, but, because of unwanted arrhythmic side-effects, they are not studied for that indication any longer. Nonetheless, the PDE3 inhibitor... | 1 | Biochemistry |
DNA ends refer to the properties of the ends of linear DNA molecules, which in molecular biology are described as "sticky" or "blunt" based on the shape of the complementary strands at the terminus. In sticky ends, one strand is longer than the other (typically by at least a few nucleotides), such that the longer stran... | 1 | Biochemistry |
An Alfvén resonator or Ionosphere Alfvén resonator is a spectral resonance structure found within geomagnetic fields in the frequency range of 0.1–10 Hz. First reported in 1989, they are ionospheric short-period geomagnetic variations primarily seen as nighttime phenomena and rarely observed during the day. The nightti... | 7 | Physical Chemistry |
Carboxylation is a standard conversion in organic chemistry. Specifically carbonation (i.e. carboxylation) of Grignard reagents and organolithium compounds is a classic way to convert organic halides into carboxylic acids.
Sodium salicylate, precursor to aspirin, is commercially prepared by treating sodium phenolate (t... | 0 | Organic Chemistry |
A proton-pumping, ubiquinone-using NADH dehydrogenase complex, homologous to complex I, is found in the chloroplast genomes of most land plants under the name ndh. This complex is inherited from the original symbiosis from cyanobacteria, but has been lost in most eukaryotic algae, some gymnosperms (Pinus and gnetophyte... | 1 | Biochemistry |
The term depletion gilding usually refers to the production of a layer of gold. However, it can also be used to produce a layer that is an alloy of gold and silver, sometimes referred to as electrum. Certain chemicals, such as oxalic acid, attack copper but do not affect either silver or gold. Using such a chemical, it... | 8 | Metallurgy |
In an isotropic and linear medium, this polarization field P is proportional and parallel to the electric field E:
where χ is the electric susceptibility of the medium. The relation between D and E is thus:
where
is the dielectric constant of the medium. The value 1+χ is called the relative permittivity of the medium,... | 3 | Analytical Chemistry |
*Volcanic eruptions release large amounts of sulphuric acid, hydrogen sulfide and hydrochloric acid into the atmosphere. These gases represent aerosols and eventually return to earth as acid rain, having a number of adverse effects on the environment and human life.
*Aerosols interact with the Earth's energy budget in ... | 7 | Physical Chemistry |
Proteins can be engineered to improve the chance of successful protein crystallization by using techniques like Surface Entropy Reduction or engineering in crystal contacts. Frequently, problematic cysteine residues can be replaced by alanine to avoid disulfide-mediated aggregation, and residues such as lysine, glutam... | 3 | Analytical Chemistry |
The first genes discovered in a mutagenesis screen for mutants unable to produce rhamnolipids were rhlA and rhlB. They are arranged in an operon, adjacent to rhlRI, a master regulator of quorum sensing in Pseudomonas aeruginosa. The proteins encoded by rhlA and rhlB; RhlA and RhlB respectively, are expected to form a c... | 0 | Organic Chemistry |
In carbohydrate chemistry, a pair of anomers () is a pair of near-identical stereoisomers or diastereomers that differ at only the anomeric carbon, the carbon that bears the aldehyde or ketone functional group in the sugar's open-chain form. However, in order for anomers to exist, the sugar must be in its cyclic form, ... | 4 | Stereochemistry |
Rosocyanine and rubrocurcumin are two red colored materials, which are formed by the reaction between curcumin and borates. | 3 | Analytical Chemistry |
Photoinhibition occurs in all organisms capable of oxygenic photosynthesis, from vascular plants to cyanobacteria. In both plants and cyanobacteria, blue light causes photoinhibition more efficiently than other wavelengths of visible light, and all wavelengths of ultraviolet light are more efficient than wavelengths of... | 5 | Photochemistry |
Both the oral and intravenous preparations of flucloxacillin are inexpensive and are available as the sodium salt flucloxacillin sodium, in capsules (250 or 500 mg), oral suspensions (125 mg/5 ml or 250 mg/5 ml), and injections (powder for reconstitution, 250, 500, 1000 and 2000 mg per vial).
Flucloxacillin is not comm... | 4 | Stereochemistry |
Choline is an essential nutrient. The cholines are a family of water-soluble quaternary ammonium compounds. Choline is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. Healthy humans fed artificially composed diets that are deficient ... | 9 | Geochemistry |
For many years, the mechanism by which RNA polymerase moves along the DNA strand during abortive initiation remained elusive. It had been observed that RNA polymerase did not escape from the promoter during transcription initiation, so it was unknown how the enzyme could read the DNA strand to transcribe it without mov... | 1 | Biochemistry |
In the cytoplasm, ferrous iron is found in a soluble, chelatable state which constitutes the labile iron pool (~0.001 mM). In this pool, iron is thought to be bound to low-mass compounds such as peptides, carboxylates and phosphates, although some might be in a free, hydrated form (aqua ions). Alternatively, iron ions ... | 1 | Biochemistry |
Formula: or
* Density: 0.180 kg/m at STP (0 °C, 101325 Pa).
* Atomic weight: 2.0141017926 Da.
* Mean abundance in ocean water (from VSMOW) 155.76 ± 0.1 atoms of deuterium per million atoms of all isotopes of hydrogen (about 1 atom of in 6420); that is, about 0.015% of all atoms of hydrogen (any isotope)
Data at appro... | 9 | Geochemistry |
Hyperchromicity is the increase of absorbance (optical density) of a material. The most famous example is the hyperchromicity of DNA that occurs when the DNA duplex is denatured. The UV absorption is increased when the two single DNA strands are being separated, either by heat or by addition of denaturant or by increas... | 7 | Physical Chemistry |
Similar to foraminifera shells, the isotopic composition of coral skeletons is used to reconstruct past temperature, CO concentrations, and pH. Vital effects arise from algal symbionts and biological responses to changes in conditions such as pH. Again, culture experiments are used to quantify vital effects and calibra... | 9 | Geochemistry |
The fundamental series is a set of spectral lines in a set caused by transition between d and f orbitals in atoms.
Originally the series was discovered in the infrared by Fowler and independently by Arno Bergmann. This resulted in the name Bergmann series used for such a set of lines in a spectrum. However the name w... | 7 | Physical Chemistry |
Artificial transactivation of a gene is achieved by inserting it into the genome at the appropriate area as transactivator gene adjoined to special promoter regions of DNA. The transactivator gene expresses a transcription factor that binds to specific promoter region of DNA. By binding to the promoter region of a gene... | 1 | Biochemistry |
Paper chromatography is one method for testing the purity of compounds and identifying substances. Paper chromatography is a useful technique because it is relatively quick and requires only small quantities of material. Separations in paper chromatography involve the principle of partition. In paper chromatography, su... | 3 | Analytical Chemistry |
Electron-withdrawing groups are the opposite effect of electron-donating groups (EDGs). Both describe functional groups, however, electron-withdrawing groups pull electron density away from a molecule, whereas EDGs push electron density onto a substituent. | 7 | Physical Chemistry |
Suspension Peroxide Oxidation Combined Acidity and Sulfur (SPOCAS) method is a suite of tests used to determine the net acidity via the measurement of: Titratable Peroxide Acidity (TPA) (as a measure of PSA); Titratable Actual Acidity (TAA); Excess Acid Neutralising Capacity (ANC); and Residual Acid Soluble Sulfur (S) ... | 9 | Geochemistry |
TCF4 proteins act as transcription factors which will bind to the immunoglobulin enhancer mu-E5/kappa-E2 motif. TCF4 activates transcription by binding to the E-box (5’-CANNTG-3’) found usually on SSTR2-INR, or somatostatin receptor 2 initiator element. TCF4 is primarily involved in neurological development of the fetu... | 1 | Biochemistry |
The mass fraction is the fraction of one substance with mass to the mass of the total mixture , defined as:
The SI unit is kg/kg. However, the deprecated parts-per notation is often used to describe small mass fractions. | 3 | Analytical Chemistry |
Vitamin A deficiency (VAD) caused night blindness is a reversible difficulty for the eyes to adjust to dim light. It is common in young children who have a diet inadequate in retinol and beta-carotene. A process called dark adaptation typically causes an increase in photopigment amounts in response to low levels of ill... | 1 | Biochemistry |
Reinforced lipids are lipid molecules in which some of the fatty acids contain deuterium instead of hydrogen. They can be used for the protection of living cells by slowing the chain reaction due to isotope effect on lipid peroxidation. The lipid bilayer of the cell and organelle membranes contain polyunsaturated fatty... | 1 | Biochemistry |
Common chemical shift ranges for nuclei within carbohydrate residues are:
*Typical H NMR chemical shifts of carbohydrate ring protons are 3–6 ppm (4.5–5.5 ppm for anomeric protons).
*Typical C NMR chemical shifts of carbohydrate ring carbons are 60–110 ppm
In the case of simple mono- and oligosaccharide molecules, all ... | 0 | Organic Chemistry |
In the pharmaceutical industry, shikimic acid from the Chinese star anise (Illicium verum) is used as a base material for production of oseltamivir (Tamiflu). Although shikimic acid is present in most autotrophic organisms, it is a biosynthetic intermediate and in general found in very low concentrations. The low isola... | 1 | Biochemistry |
The overall reaction catalyzed by ETF-QO is as follows:
ETF-QO(red) + ubiquinone ↔ ETF-QO(ox) + ubiquinol
Enzymatic activity is usually assayed spectrophotometrically by reaction with octanoyl-CoA as the electron donor and ubiquinone-1 as the electron acceptor. The enzyme can also be assayed via disproportionation of E... | 1 | Biochemistry |
Ethyl bromoacetate is the chemical compound with the formula . It is the ethyl ester of bromoacetic acid and is prepared in two steps from acetic acid. It is a lachrymator and has a fruity, pungent odor. It is also a highly toxic alkylating agent and may be fatal if inhaled. | 0 | Organic Chemistry |
Coordination cages are three-dimensional ordered structures in solution that act as hosts in host–guest chemistry. They are self-assembled in solution from organometallic precursors, and often rely solely on noncovalent interactions rather than covalent bonds. Coordinate bonds are useful in such supramolecular self-ass... | 6 | Supramolecular Chemistry |
The fineness of a precious metal object (coin, bar, jewelry, etc.) represents the weight of fine metal therein, in proportion to the total weight which includes alloying base metals and any impurities. Alloy metals are added to increase hardness and durability of coins and jewelry, alter colors, decrease the cost per w... | 8 | Metallurgy |
Paired-end tags (PET) (sometimes "Paired-End diTags", or simply "ditags") are the short sequences at the 5’ and 3 ends of a DNA fragment which are unique enough that they (theoretically) exist together only once in a genome, therefore making the sequence of the DNA in between them available upon search (if full-genome ... | 1 | Biochemistry |
Mass spectrometry methods are generally used for analysis of environmental contaminant monitoring, particularly in aquatic environments (though they can be applied in non-aquatic environments, such as with screening pesticides on plant matter), paired with chromatography for separation. For target screening, this means... | 3 | Analytical Chemistry |
A Metabolic Panel (MP) is a routine group of blood tests commonly used for health screenings, disease detection, and monitoring vital signs of hospitalized patients with specific medical conditions. MP panel analyzes common analytes in the blood to assess the functions of the kidneys and liver, as well as electrolyte a... | 1 | Biochemistry |
Single-Molecule electrochemistry is an electrochemical technique used to study the faradaic response of redox molecules in electrochemical environments. The ability to study singular molecules gives rise to the potential of developing ultra-sensitive sensors which are necessary in SEE. From the work of Bard and Fan, th... | 7 | Physical Chemistry |
For electrolyte solution in a channel with a macro- or micro-scaled radius, surface charges at the wall attract counterions and repel co-ions due to electrostatic force. Therefore, an electrical double layer exists between the wall of channel and the solution. The dimension of the electrical double layer is determined ... | 7 | Physical Chemistry |
In 1989, Alan Mackay suggested that if chemical synthesis could be used to make L-protein and D-protein enantiomers, it would enable the use of racemic mixtures to crystallize proteins in centrosymmetric space groups. He stated that, because in the X-ray diffraction data obtained from a centrosymmetric crystal the off-... | 3 | Analytical Chemistry |
6-Phosphogluconolactone is an intermediate in the pentose phosphate pathway (PPP).
In the PPP pathway, it is produced from glucose-6-phosphate by glucose-6-phosphate dehydrogenase. It is then converted to 6-Phosphogluconic acid by 6-phosphogluconolactonase. | 1 | Biochemistry |
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