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Heterosynaptic plasticity (or also heterotropic modulation) is a change in synaptic strength that results from the activity of other neurons. Again, the plasticity can alter the number of vesicles or their replenishment rate or the relationship between calcium and vesicle release. Additionally, it could directly affec... | 1 | Gene expression + Signal Transduction |
At the beginning of the twentieth century, as steel production became more dependent on the use of electric arc furnace technology in mini-mill environments, the convenient transportation of scrap metal became a competitive advantage of manufacturers, so the availability of geographical resources was no longer the most... | 0 | Metallurgy |
In materials science, grain-boundary strengthening (or Hall–Petch strengthening) is a method of strengthening materials by changing their average crystallite (grain) size. It is based on the observation that grain boundaries are insurmountable borders for dislocations and that the number of dislocations within a grain ... | 0 | Metallurgy |
Proteins are the product of a gene that are formed from translation of a mature mRNA molecule. Proteins contain 4 elements in regards to their structure: primary, secondary, tertiary and quaternary. The linear amino acid sequence is also known as the primary structure. Hydrogen bonding between the amino acids of the pr... | 1 | Gene expression + Signal Transduction |
A position of a codon is said to be a n-fold degenerate site if only n of four possible nucleotides (A, C, G, T) at this position specify the same amino acid. A nucleotide substitution at a 4-fold degenerate site is always a synonymous mutation with no change on the amino acid.
A less degenerate site would produce a no... | 1 | Gene expression + Signal Transduction |
Sintering or frittage is the process of compacting and forming a solid mass of material by pressure or heat without melting it to the point of liquefaction. Sintering happens as part of a manufacturing process used with metals, ceramics, plastics, and other materials. The nanoparticles in the sintered material diffuse ... | 0 | Metallurgy |
HACNS1 (also known as CENTG2 and located in the Human Accelerated Region 2) is a gene enhancer "that may have contributed to the evolution of the uniquely opposable human thumb, and possibly also modifications in the ankle or foot that allow humans to walk on two legs". Evidence to date shows that of the 110,000 gene e... | 1 | Gene expression + Signal Transduction |
β-Catenin has a central role in directing several developmental processes, as it can directly bind transcription factors and be regulated by a diffusible extracellular substance: Wnt. It acts upon early embryos to induce entire body regions, as well as individual cells in later stages of development. It also regulates ... | 1 | Gene expression + Signal Transduction |
The most common standard in Europe is ISO 9454-1 (also known as DIN EN 29454-1).
This standard specifies each flux by a four-character code: flux type, base, activator, and form. The form is often omitted.
Therefore, 1.1.2 means rosin flux with halides. | 0 | Metallurgy |
Most class III adenylyl cyclases are transmembrane proteins with 12 transmembrane segments. The protein is organized with 6 transmembrane segments, then the C1 cytoplasmic domain, then another 6 membrane segments, and then a second cytoplasmic domain called C2. The important parts for function are the N-terminus and th... | 1 | Gene expression + Signal Transduction |
A wide variety of algorithms have been developed to facilitate detection of promoters in genomic sequence, and promoter prediction is a common element of many gene prediction methods. A promoter region is located before the -35 and -10 Consensus sequences. The closer the promoter region is to the consensus sequences th... | 1 | Gene expression + Signal Transduction |
It was established by the decree of Peter the Great to process the local copper deposits. The Polevskoy Plant was named after the local river Polevaya. The plant became the basis for the settlement which later grew into the town of Polevskoy.
The place for a new plant was chosen by Vasily Tatishchev. Georg Wilhelm de G... | 0 | Metallurgy |
As hormones are defined functionally, not structurally, they may have diverse chemical structures. Hormones occur in multicellular organisms (plants, animals, fungi, brown algae, and red algae). These compounds occur also in unicellular organisms, and may act as signaling molecules however there is no agreement that th... | 1 | Gene expression + Signal Transduction |
mRNA binding allows repression of protein translation through direct blocking, degradation or cleavage of mRNA. Certain mRNA binding mechanisms have high specificity, which can act as a form of the intrinsic immune response during certain viral infections. Certain segmented RNA viruses can also regulate viral gene expr... | 1 | Gene expression + Signal Transduction |
In metallurgy, materials science and structural geology, subgrain rotation recrystallization is recognized as an important mechanism for dynamic recrystallisation. It involves the rotation of initially low-angle sub-grain boundaries until the mismatch between the crystal lattices across the boundary is sufficient for t... | 0 | Metallurgy |
Growth factor and clotting factors are paracrine signaling agents. The local action of growth factor signaling plays an especially important role in the development of tissues. Also, retinoic acid, the active form of vitamin A, functions in a paracrine fashion to regulate gene expression during embryonic development in... | 1 | Gene expression + Signal Transduction |
The first known use of metals in the Southern Levant is during the Chalcolithic period (end of 5th–most of the 4th millennium BCE). More than 500 metal objects were found, mainly in hoards, burials, and habitation
remains. Most of the metals originate from sites in the southern part of Israel and Jordan; very rarely do... | 0 | Metallurgy |
NASA used additive manufacturing to synthesize an alloy they termed GRX-810, which survived temperatures over . The alloy also featured improved strength, malleability, and durability. The printer dispersed oxide particles uniformly throughout the metal matrix. The alloy was identified using 30 simulations of thermodyn... | 0 | Metallurgy |
The deepest gold mines of the Ancient world were found in the Maski region in Karnataka. There were ancient silver mines in northwest India. Dated to the middle of the 1st millennium BCE. gold and silver were also used for making utensils for the royal family and nobilities.the royal family wore costly fabrics that wer... | 0 | Metallurgy |
Calcineurin along with NFAT, may improve the function of diabetics' pancreatic beta cells. Thus tacrolimus contributes to the frequent development of new diabetes following renal transplantation.
Calcineurin/NFAT signaling is required for perinatal lung maturation and function. | 1 | Gene expression + Signal Transduction |
Ferrous metallurgy is the metallurgy of iron and its alloys. The earliest surviving prehistoric iron artifacts, from the 4th millennium BC in Egypt, were made from meteoritic iron-nickel. It is not known when or where the smelting of iron from ores began, but by the end of the 2nd millennium BC iron was being produced ... | 0 | Metallurgy |
Prehistoric links between Mesoamerica and the Andes have been suggested on several occasions. Early Mesoamerican and Ecuadorian pottery style show some similarities, both in technique and motifs. Likewise, similarities in early burial styles (so-called "shaft tombs") present in Ecuador and western Mesoamerica have been... | 0 | Metallurgy |
Although traditionally thought to form at compositions XYZ and XYZ, studies published after 2015 have discovered and reliably predicted Heusler compounds with atypical compositions such as XYZ and XYZ. Besides these ternary compositions, quaternary Heusler compositions called the double Half-Heusler XYYZ (e.g. TiFeNiS... | 0 | Metallurgy |
WECs are sub-surface white cracks networks within local microstructural changes that are characterised by a changed microstructure known as white etching area (WEA). The term "white etching" refers to the white appearance of the altered microstructure of a polished and etched steel sample in the affected areas. The WEA... | 0 | Metallurgy |
A bacterial initiation factor (IF) is a protein that stabilizes the initiation complex for polypeptide translation.
Translation initiation is essential to protein synthesis and regulates mRNA translation fidelity and efficiency in bacteria. The 30S ribosomal subunit, initiator tRNA, and mRNA form an initiation complex ... | 1 | Gene expression + Signal Transduction |
Değirmentepe or Değirmentepe Hüyük is an archaeological site which is located at 50 km north of the river Euphrates and at 24 km in the northeast of Malatya province in eastern Anatolia. It is now submerged in the reservoir area of the Karakaya and Atatürk dams. Rescue excavations were undertaken in under the supervis... | 0 | Metallurgy |
Iron smelting was unknown in pre-Columbian America.
Excavations at LAnse aux Meadows, Newfoundland, have found considerable evidence for the processing of bog iron and the production of iron in a bloomery by the Norse. The cluster of Viking Age (–1022 AD) at LAnse aux Meadows are situated on a raised marine terrace, be... | 0 | Metallurgy |
The fraction of tailings to ore can range from 90 to 98% for some copper ores to 20–50% of the other (less valuable) minerals. The rejected minerals and rocks liberated through mining and processing have the potential to damage the environment by releasing toxic metals (arsenic and mercury being two major culprits), by... | 0 | Metallurgy |
Recent work has investigated the role of enhancers in morphological changes in threespine stickleback fish. Sticklebacks exist in both marine and freshwater environments, but sticklebacks in many freshwater populations have completely lost their pelvic fins (appendages homologous to the posterior limb of tetrapods).<br... | 1 | Gene expression + Signal Transduction |
In the field of molecular biology, the cAMP-dependent pathway, also known as the adenylyl cyclase pathway, is a G protein-coupled receptor-triggered signaling cascade used in cell communication. | 1 | Gene expression + Signal Transduction |
The choice of metallic substrate is determined by the dimensional, mechanical and corrosion resistance properties required of the coated product in use. The most common metallic substrates that are organically coated are:
* Hot dip galvanised steel (HDG) which consists of a cold reduced steel substrate onto which a lay... | 0 | Metallurgy |
C/EBP proteins interact with the CCAAT (cytosine-cytosine-adenosine-adenosine-thymidine) box motif, which is present in several gene promoters. They are characterized by a highly conserved basic-leucine zipper (bZIP) domain at the C-terminus. This domain is involved in dimerization and DNA binding, as are other transcr... | 1 | Gene expression + Signal Transduction |
In materials science, critical resolved shear stress (CRSS) is the component of shear stress, resolved in the direction of slip, necessary to initiate slip in a grain. Resolved shear stress (RSS) is the shear component of an applied tensile or compressive stress resolved along a slip plane that is other than perpendicu... | 0 | Metallurgy |
In anti-tank warfare, spalling through mechanical stress is an intended effect of high-explosive squash head (HESH) anti-tank shells and many other munitions, which may not be powerful enough to pierce the armour of a target. The relatively soft warhead, containing or made of plastic explosive, flattens against the arm... | 0 | Metallurgy |
Direct reduction processes can be divided roughly into two categories: gas-based and coal-based. In both cases, the objective of the process is to remove the oxygen contained in various forms of iron ore (sized ore, concentrates, pellets, mill scale, furnace dust, etc.) in order to convert the ore to metallic iron, wit... | 0 | Metallurgy |
The Blepharisma nuclear code (translation table 15) is a genetic code found in the nuclei of Blepharisma. | 1 | Gene expression + Signal Transduction |
The glycoprotein consists of a homodimer of 180 kDA stabilized by intermolecular disulfide bonds. It has a large extracellular domain of about 561 amino acids, a hydrophobic transmembrane domain and a short cytoplasmic tail domain composed of 45 amino acids. The 260 amino acid region closest to the extracellular membra... | 1 | Gene expression + Signal Transduction |
These adenylyl cyclases are toxins secreted by pathogenic bacteria such as Bacillus anthracis, Bordetella pertussis, Pseudomonas aeruginosa, and Vibrio vulnificus during infections. These bacteria also secrete proteins that enable the AC-II to enter host cells, where the exogenous AC activity undermines normal cellular... | 1 | Gene expression + Signal Transduction |
Under the split gene theory, an exon is defined by an ORF. It requires a mechanism to recognize an ORF to have originated. As an ORF is defined by a contiguous coding sequence bounded by stop codons, these stop codon ends had to be recognized by the exon-intron gene recognition system. This system could have defined th... | 1 | Gene expression + Signal Transduction |
Two groups of well-known mimicking molecules include halogenated furanones, which mimic AHL molecules, and synthetic Al peptides (AIPs), which mimic naturally occurring AIPs. These groups inhibit receptors from binding substrate or decrease the concentration of receptors in the cell. Furanones have also been found to a... | 1 | Gene expression + Signal Transduction |
Casting processes simulation uses numerical methods to calculate cast component quality considering mold filling, solidification and cooling, and provides a quantitative prediction of casting mechanical properties, thermal stresses and distortion. Simulation accurately describes a cast component's quality up-front befo... | 0 | Metallurgy |
The carboxy-terminal domain is also the binding site of the cap-synthesizing and cap-binding complex. In eukaryotes, after transcription of the 5 end of an RNA transcript, the cap-synthesizing complex on the CTD will remove the gamma-phosphate from the 5-phosphate and attach a GMP, forming a 5,5-triphosphate linkage. ... | 1 | Gene expression + Signal Transduction |
Zinc pest (from German Zinkpest "zinc plague"), also known as zinc rot and zamak rot, is a destructive, intercrystalline corrosion process of zinc alloys containing lead impurities. While impurities of the alloy are the primary cause of the problem, environmental conditions such as high humidity (greater than 65%) may ... | 0 | Metallurgy |
Metal sulfides (e.g., pyrite FeS, arsenopyrite FeAsS, chalcopyrite CuFeS) are normally processed by chemical oxidation either in aqueous media or at high temperatures. In fact, most base metals, e.g., aluminium, chromium, must be (electro)chemically reduced at high temperatures by which the process entails a high energ... | 0 | Metallurgy |
Recovery of metals from oxide matrixes is generally carried out using mineral acids. However, electrochemical dissolution of metal oxides in DES can allow to enhance the dissolution up to more than 10 000 times in pH neutral solutions.
Studies have shown that ionic oxides such as ZnO tend to have high solubility in ChC... | 0 | Metallurgy |
CK1ε and CK1δ are essential in the genetic transcription-translation (and post-translation) feedback loops that generate circadian rhythm in mammals.
The previously-characterized CK1ε isoform was first implicated as a clock gene when its Drosophila homolog, double-time (Doubletime (gene)), was discovered in 1998. Doubl... | 1 | Gene expression + Signal Transduction |
Pioneer factors can also affect transcription and differentiation through the control of DNA methylation. Pioneer factors that bind to CpG islands and cytosine residues block access to methyltransferases. Many eukaryotic cells have CpG islands in their promoters that can be modified by methylation having adverse effe... | 1 | Gene expression + Signal Transduction |
In mining, tailings or tails are the materials left over after the process of separating the valuable fraction from the uneconomic fraction (gangue) of an ore. Tailings are different from overburden, which is the waste rock or other material that overlies an ore or mineral body and is displaced during mining without be... | 0 | Metallurgy |
Clinical and translational data suggest that sensitive tumor types, with adequate parameters and functional apoptosis pathways, might not need high doses of mTOR inhibitors to trigger apoptosis. In most cases, cancer cells might only be partially sensitive to mTOR inhibitors due to redundant signal transduction or lack... | 1 | Gene expression + Signal Transduction |
Reverberatory furnaces are long furnaces that can treat wet, dry, or roasted concentrate. Most of the reverberatory furnaces used in the latter years treated roasted concentrate because putting dry feed materials into the reverberatory furnace is more energy efficient, and because the elimination of some of the sulfur ... | 0 | Metallurgy |
Homeobox protein NANOG (hNanog) is a transcriptional factor that helps embryonic stem cells (ESCs) maintain pluripotency by suppressing cell determination factors. hNanog is encoded in humans by the NANOG gene. Several types of cancer are associated with NANOG. | 1 | Gene expression + Signal Transduction |
Anaerobic oxidation of iron and steel commonly finds place in oxygen-depleted environments, such as in permanently water-saturated soils, peat bogs or wetlands in which archaeological iron artefacts are often found.
Anaerobic oxidation of carbon steel of canisters and overpacks is also expected to occur in deep geologi... | 0 | Metallurgy |
RopB transcriptional regulator, also known as RopB/Rgg transcriptional regulator is a transcriptional regulator protein that regulates expression of the extracellularly secreted cysteine protease streptococcal pyrogenic exotoxin B (speB) [See Also: erythrogenic toxins] which is an important virulence factor of Streptoc... | 1 | Gene expression + Signal Transduction |
Gene knockouts (also known as gene deletion or gene inactivation) are a widely used genetic engineering technique that involves the targeted removal or inactivation of a specific gene within an organism's genome. This can be done through a variety of methods, including homologous recombination, CRISPR-Cas9, and TALENs.... | 1 | Gene expression + Signal Transduction |
Freeze–thaw weathering is caused by moisture freezing inside cracks in rock. Upon freezing its volume expands, causing large forces which cracks spall off the outer surface. As this cycle repeats the outer surface repeatedly undergoes spalling, resulting in weathering.
Some stone and masonry surfaces used as building s... | 0 | Metallurgy |
Spatiotemporal gene expression is the activation of genes within specific tissues of an organism at specific times during development. Gene activation patterns vary widely in complexity. Some are straightforward and static, such as the pattern of tubulin, which is expressed in all cells at all times in life. Some, on t... | 1 | Gene expression + Signal Transduction |
The HMG proteins are subdivided into 3 superfamilies each containing a characteristic functional domain:
* HMGA – contains an AT-hook domain
** HMGA1
** HMGA2
* HMGB – contains a HMG-box domain
** HMGB1
** HMGB2
** HMGB3
** HMGB4
* HMGN – contains a nucleosomal binding domain
** HMGN1
** HMGN2
** HMGN3
** HMGN4
** HMGN... | 1 | Gene expression + Signal Transduction |
Corrosion in Ballast Tanks is the deterioration process where the surface of a ballast tank progresses from microblistering, to hydroscaletric electration, and finally to cracking of the tank steel itself.
::“Effective corrosion control in segregated water ballast spaces is probably the single most important feature, n... | 0 | Metallurgy |
Heavy chain contains similar gene segments such as VH, JH and CH, but also has another gene segment called D (diversity). Unlike the light chain multigene family, VDJ gene segments code for the variable region of the heavy chain. The rearrangement and reorganization of gene segments in this multigene family is more co... | 1 | Gene expression + Signal Transduction |
Chromatin remodeling plays a central role in the regulation of gene expression by providing the transcription machinery with dynamic access to an otherwise tightly packaged genome. Further, nucleosome movement by chromatin remodelers is essential to several important biological processes, including chromosome assembly ... | 1 | Gene expression + Signal Transduction |
Due to the biological complexity of gene expression, the considerations of experimental design that are discussed in the expression profiling article are of critical importance if statistically and biologically valid conclusions are to be drawn from the data.
There are three main elements to consider when designing a m... | 1 | Gene expression + Signal Transduction |
DNA repair genes are frequently repressed in cancers due to hypermethylation of CpG islands within their promoters. In head and neck squamous cell carcinomas at least 15 DNA repair genes have frequently hypermethylated promoters; these genes are XRCC1, MLH3, PMS1, RAD51B, XRCC3, RAD54B, BRCA1, SHFM1, GEN1, FANCE, FAAP... | 1 | Gene expression + Signal Transduction |
When stored in air, it forms a yellow potassium superoxide coating and may ignite. This superoxide reacts explosively with water and organics. NaK is not dense enough to sink in most hydrocarbons, but will sink in lighter mineral oil. It is unsafe to store in this manner if the superoxide has formed. A large explosion ... | 0 | Metallurgy |
Signal peptides are extremely heterogeneous, many prokaryotic and eukaryotic ones are functionally interchangeable within or between species and all determine protein secretion efficiency. | 1 | Gene expression + Signal Transduction |
Atmospheric corrosion generally refers to general corrosion in a non-specific environment. Prevention of atmospheric corrosion is typically handled by use of materials selection and coatings specifications. The use of zinc coatings also known as galvanization on steel structures is a form of cathodic protection where t... | 0 | Metallurgy |
The rust resistance of EPS-processed steel strip is superior to that of acid pickled steel strip primarily because acid pickling imposes a corrosion "penalty" on the steel which EPS processing does not. This penalty is a result of chemical reactions that occur after acid pickling and serve as a catalyst for oxidation. ... | 0 | Metallurgy |
There is varying impact on local corrosion noted from biofilms formed of diverse microbial communities. For instance, when isolating a sample of biofilm from a pipe within the first week of growth, the corrosion of the pipe accelerated, yet by the end of a month, the same biofilm began to act as a protective layer for ... | 0 | Metallurgy |
The inhabitants of Ban Na Di were casting bronze from to 200 AD, using the lost-wax technique to manufacture bangles. Bangles made by the lost-wax process are characteristic of northeast Thailand. Some of the bangles from Ban Na Di revealed a dark grey substance between the central clay core and the metal, which on an... | 0 | Metallurgy |
A signal peptide (sometimes referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a short peptide (usually 16-30 amino acids long) present at the N-terminus (or occasionally nonclassically at the C-terminus or internally) of... | 1 | Gene expression + Signal Transduction |
Vacuum arc remelting (VAR) is a secondary melting process for production of metal ingots with elevated chemical and mechanical homogeneity for highly demanding applications. The VAR process has revolutionized the specialty traditional metallurgical techniques industry, and has made possible tightly-controlled material... | 0 | Metallurgy |
The first commercial primary-lead ISASMELT furnace was installed at the Yunnan Chihong Zinc and Germanium Company Limited (YCZG) greenfield zinc and lead smelting complex at Qujing in Yunnan Province in China. This furnace was part of a plant consisting of the ISASMELT furnace and a blast furnace specially designed to ... | 0 | Metallurgy |
The BASIC assembly strategy was developed in 2015 and sought to address the limitations of previous assembly techniques, incorporating six key concepts from them: standard reusable parts; single-tier format (all parts are in the same format and are assembled using the same process); idempotent cloning; parallel (multip... | 1 | Gene expression + Signal Transduction |
Although an attenuation mechanism that involves translation while transcription is ongoing, like to the mechanism for the trp operon (and some other amino acid biosynthetic operons), would not work in eukaryotes, there is evidence for attenuation in Eukaryotes. Research conducted on microRNA processing provides evidenc... | 1 | Gene expression + Signal Transduction |
Incidental decarburization can be detrimental to surface properties in products (where carbon content is desirable) when done during heat treatment or after rolling or forging, because the material is only affected to a certain depth according to the temperature and duration of heating. This can be prevented by using a... | 0 | Metallurgy |
The Lamberhurst Foundry is believed to have been the maker in 1710–14 of some of the earliest cast-iron railings produced in England, which they made for St Paul's Cathedral, despite the objections of Christopher Wren, who did not want a fence around the Cathedral at all, and said that if there had to be one it should ... | 0 | Metallurgy |
Changes in promoter sequences are critical in evolution as indicated by the relatively stable number of genes in many lineages. For instance, most vertebrates have roughly the same number of protein-coding genes (about 20,000) which are often highly conserved in sequence, hence much of evolutionary change must come fro... | 1 | Gene expression + Signal Transduction |
Since the ERK signaling pathway is involved in both physiological and pathological cell proliferation, it is natural that ERK1/2 inhibitors would represent a desirable class of antineoplastic agents. Indeed, many of the proto-oncogenic "driver" mutations are tied to ERK1/2 signaling, such as constitutively active (muta... | 1 | Gene expression + Signal Transduction |
Biogenic sulfide corrosion is a bacterially mediated process of forming hydrogen sulfide gas and the subsequent conversion to sulfuric acid that attacks concrete and steel within wastewater environments. The hydrogen sulfide gas is biochemically oxidized in the presence of moisture to form sulfuric acid. The effect o... | 0 | Metallurgy |
The 3′-UTR often contains microRNA response elements (MREs), which are sequences to which miRNAs bind. miRNAs are short, non-coding RNA molecules capable of binding to mRNA transcripts and regulating their expression. One miRNA mechanism involves partial base pairing of the 5' seed sequence of an miRNA to an MRE within... | 1 | Gene expression + Signal Transduction |
This gene contains a single nucleotide polymorphism that causes an amino acid substitution within the 11 of 12 ankyrin repeats of ANKK1 (Glu713Lys of 765 residues). This polymorphism, which is commonly referred to Taq1A, was previously believed to be located in the promoter region of the DRD2 gene, since the polymorphi... | 1 | Gene expression + Signal Transduction |
Over-activation of mTOR signaling significantly contributes to the initiation and development of tumors and mTOR activity was found to be deregulated in many types of cancer including breast, prostate, lung, melanoma, bladder, brain, and renal carcinomas. Reasons for constitutive activation are several. Among the most ... | 1 | Gene expression + Signal Transduction |
The Sawmill is run by a D-3000 Cat diesel engine, Hawthorne Machinery in San Diego provided the cylinder liners. The Sawmill was re-assembled and improved following a donation from the Pederson Brothers who had operated it in the Big Bear area years ago. This is likely the only Sawmill that can be seen operating in San... | 0 | Metallurgy |
Electroforming is a metal forming process in which parts are fabricated through electrodeposition on a model, known in the industry as a mandrel. Conductive (metallic) mandrels are treated to create a mechanical parting layer, or are chemically passivated to limit electroform adhesion to the mandrel and thereby allow i... | 0 | Metallurgy |
The cyanide remaining in tails streams from gold plants is potentially hazardous. Therefore, some operations process the cyanide-containing waste streams in a detoxification step. This step lowers the concentrations of these cyanide compounds. The INCO-licensed process and the Caro's acid process oxidise the cyanide to... | 0 | Metallurgy |
There are currently three methods in use that involve precisely targeting a DNA sequence in order to introduce a double-stranded break. Once this occurs, the cell's repair mechanisms will attempt to repair this double stranded break, often through non-homologous end joining (NHEJ), which involves directly ligating the ... | 1 | Gene expression + Signal Transduction |
Bronze Age goldwork is marked by an elegant simplicity of design and fine execution, with decoration usually restricted to relatively simple geometric patterns such as parallel lines, chevron, zig-zag and circular patterns, often extremely small and perfectly executed, especially in Ireland, as can be seen by enlarging... | 0 | Metallurgy |
There are two main groups of paired receptors, distinguished by extracellular regions containing immunoglobulin or C-type lectin domains. Nomenclature within these families is complex and has changed over time as new members were identified. In general, the example of the LILR family applies; genes designated A represe... | 1 | Gene expression + Signal Transduction |
In case of the fungus Neurospora crassa, the circadian clock is controlled by two light-sensitive domains, known as the white-collar-complex (WCC) and the LOV domain vivid (VVD-LOV). WCC is primarily responsible for the light-induced transcription on the control-gene frequency (FRQ) under day-light conditions, which dr... | 1 | Gene expression + Signal Transduction |
Ellingham diagrams are a particular graphical form of the principle that the thermodynamic feasibility of a reaction depends on the sign of ΔG, the Gibbs free energy change, which is equal to ΔH − TΔS, where ΔH is the enthalpy change and ΔS is the entropy change.
The Ellingham diagram plots the Gibbs free energy change... | 0 | Metallurgy |
The locus of enterocyte effacement-encoded regulator (Ler) is a regulatory protein that controls bacterial pathogenicity of enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic Escherichia coli (EHEC). More specifically, Ler regulates the locus of enterocyte effacement (LEE) pathogenicity island genes, which ... | 1 | Gene expression + Signal Transduction |
Metal dusting is "a catastrophic form of corrosion that occurs when susceptible materials are exposed to environments with high carbon activities." The corrosion manifests itself as a break-up of bulk metal to metal powder. The suspected mechanism is firstly the deposition of a graphite layer on the surface of the meta... | 0 | Metallurgy |
Establishing body axes is a critical step in animal development. During mouse embryonic development, Nodal, a transforming growth factor-beta superfamily ligand, is a key gene involved in patterning both the anterior-posterior axis and the left-right axis of the early embryo. The Nodal gene contains two enhancers: the ... | 1 | Gene expression + Signal Transduction |
Phosphatidic acids are anionic phospholipids important to cell signaling and direct activation of lipid-gated ion channels. Hydrolysis of phosphatidic acid gives rise to one molecule each of glycerol and phosphoric acid and two molecules of fatty acids. They constitute about 0.25% of phospholipids in the bilayer. | 1 | Gene expression + Signal Transduction |
The type of growth factor signaling can effect whether or not NSCs differentiate into motor neurons or not. Priming a media with FGF2 lowers the activity of the PI3K/AKT pathway, which activates GSK3β. This increases expression of HB9. Directly inhibiting PI3K in NSCs leads to a population of cells that are purely HB9+... | 1 | Gene expression + Signal Transduction |
DNA-directed RNA interference (ddRNAi) is a gene-silencing technique that utilizes DNA constructs to activate an animal cell's endogenous RNA interference (RNAi) pathways. DNA constructs are designed to express self-complementary double-stranded RNAs, typically short-hairpin RNAs, that bring about the silencing of a ta... | 1 | Gene expression + Signal Transduction |
(AD 900–1450)
Utilitarian and ceremonial objects; Objects of personal adornment'
#Atotonilco, Hidalgo
#Calixtlahuaca, Mexico
#Tenayuca, Mexico
#Tenochitlan, Distrito Federal (D.F.)
#Teotihuacan, Mexico
#Texcoco, Mexico | 0 | Metallurgy |
Bounded by impoundments (an impoundment is a dam), these dams typically use "local materials" including the tailings themselves, and may be considered embankment dams. Traditionally, the only option for tailings storage was to contain the tailings slurry with locally available earthen materials. This slurry is a dilute... | 0 | Metallurgy |
The first serious attempt at providing a physical explanation of the material removal during electric discharge machining is perhaps that of Van Dijck. Van Dijck presented a thermal model together with a computational simulation to explain the phenomena between the electrodes during electric discharge machining. Howeve... | 0 | Metallurgy |
Under the light microscope, eyespots appear as dark, orange-reddish spots or stigmata. They get their color from carotenoid pigments contained in bodies called pigment granules. The photoreceptors are found in the plasma membrane overlaying the pigmented bodies.
The eyespot apparatus of Euglena comprises the paraflage... | 1 | Gene expression + Signal Transduction |
The discovery of mTOR was made in 1994 while investigating the mechanism of action of its inhibitor, rapamycin. Rapamycin was first discovered in 1975 in a soil sample from Easter Island of South Pacific, also known as Rapa Nui, from where its name is derived. Rapamycin is a macrolide, produced by the microorganism Str... | 1 | Gene expression + Signal Transduction |
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