text
stringlengths
105
13.7k
label
int64
0
1
label_text
stringclasses
2 values
Surface integrity is the surface condition of a workpiece after being modified by a manufacturing process. The term was coined by Michael Field and John F. Kahles in 1964. The surface integrity of a workpiece or item changes the material's properties. The consequences of changes to surface integrity are a mechanical en...
0
Metallurgy
Homologous desensitization occurs when a receptor decreases its response to an agonist at high concentration. It is a process through which, after prolonged agonist exposure, the receptor is uncoupled from its signaling cascade and thus the cellular effect of receptor activation is attenuated. Homologous desensitizatio...
1
Gene expression + Signal Transduction
Grain refinement, also known as inoculation, is the set of techniques used to implement grain boundary strengthening in metallurgy. The specific techniques and corresponding mechanisms will vary based on what materials are being considered. One method for controlling grain size in aluminum alloys is by introducing part...
0
Metallurgy
Ultrasonic impact treatment (UIT) is a metallurgical processing technique, similar to work hardening, in which ultrasonic energy is applied to a metal object. This technique is part of the High Frequency Mechanical Impact (HFMI) processes. Other acronyms are also equivalent: Ultrasonic Needle Peening (UNP), Ultrasonic...
0
Metallurgy
The bacterial natural product rapamycin or sirolimus, a cytostatic agent, has been used in combination therapy with corticosteroids and cyclosporine in patients who received kidney transplantation to prevent organ rejection both in the US and Europe, due to its unsatisfying pharmacokinetic properties. In 2003, the U.S...
1
Gene expression + Signal Transduction
The hallmark difference of elongation in eukaryotes in comparison to prokaryotes is its separation from transcription. While prokaryotes are able to undergo both cellular processes simultaneously, the spatial separation that is provided by the nuclear membrane prevents this coupling in eukaryotes. Eukaryotic elongation...
1
Gene expression + Signal Transduction
For U.S. food and dietary supplement labeling purposes the amount in a serving is expressed as a percent of Daily Value (%DV). For calcium labeling purposes 100% of the Daily Value was 1000 mg, but as of May 27, 2016 it was revised to 1300 mg to bring it into agreement with the RDA. A table of the old and new adult dai...
1
Gene expression + Signal Transduction
Basic oxygen steelmaking (BOS, BOP, BOF, or OSM), also known as Linz-Donawitz steelmaking or the oxygen converter process, is a method of primary steelmaking in which carbon-rich molten pig iron is made into steel. Blowing oxygen through molten pig iron lowers the carbon content of the alloy and changes it into low-car...
0
Metallurgy
Tank leaching is usually differentiated from vat leaching on the following factors: # In tank leaching the material is ground sufficiently fine to form a slurry or pulp, which can flow under gravity or when pumped. In vat leaching typically a coarser material is placed in the vat for leaching, this reduces the cost of ...
0
Metallurgy
Iron levels in cells are maintained by translation regulation of many proteins involved in iron storage and metabolism. The 5′ UTR has the ability to form a hairpin loop secondary structure (known as the iron response element or IRE) that is recognized by iron-regulatory proteins (IRP1 and IRP2). In low levels of iron,...
1
Gene expression + Signal Transduction
PAF is a potent activator of platelet aggregation, inflammation, and anaphylaxis. It is similar to the ubiquitous membrane phospholipid phosphatidylcholine except that it contains an acetyl-group in the SN-2 position and the SN-1 position contains an ether-linkage. PAF signals through a dedicated G-protein coupled re...
1
Gene expression + Signal Transduction
Metallography is the study of the physical structure and components of metals, by using microscopy. Ceramic and polymeric materials may also be prepared using metallographic techniques, hence the terms ceramography, plastography and, collectively, materialography.
0
Metallurgy
The presence of nitrogen activates the csiR gene located downstream of the gabP gene. The csiR gene encodes a protein that acts as a transcriptional repressor for csiD-ygaF-gab operon hence shutting off the GABA degradation pathway.
1
Gene expression + Signal Transduction
Fas forms the death-inducing signaling complex (DISC) upon ligand binding. Membrane-anchored Fas ligand trimer on the surface of an adjacent cell causes oligomerization of Fas. Recent studies which suggested the trimerization of Fas could not be validated. Other models suggested the oligomerization up to 5–7 Fas molecu...
1
Gene expression + Signal Transduction
The binding and cyclizing of adenosine 5’ triphosphate (ATP) to the catalytic active site of the enzyme is coordinated by two metal cations. The catalytic activity of sAC is increase by the presence of manganese [Mn]. sAC magnesium [Mg] activity is regulated by calcium [Ca] which increases the affinity for ATP of mamma...
1
Gene expression + Signal Transduction
Reverse transfection is a technique for the transfer of genetic material into cells. As DNA is printed on a glass slide for the transfection process (the deliberate introduction of nucleic acids into cells) to occur before the addition of adherent cells, the order of addition of DNA and adherent cells is reverse that o...
1
Gene expression + Signal Transduction
The development of resistance to chemotherapies such as paclitaxel and cisplatin in non-small-cell lung cancer (NSCLC) is strongly associated with overexpression of beta III tubulin. Investigations by the Children's Cancer Institute Australia (University of NSW, Lowy Cancer Research Centre) demonstrated that beta III-t...
1
Gene expression + Signal Transduction
The identification of MEKK1-MKK1/2-MPK4 in pathogen signaling has been a tremendous finding. Mekk1, mkk1/mkk2 double and mpk4 mutations are dwarfed and acquire too much of reactive oxygen species. The mutations are considered to be from the enhancement of SA levels, which is partially reversed by bacterial SA hydrolase...
1
Gene expression + Signal Transduction
The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR). Its activation is necessary for the hormonal functioning of FSH. FSHRs are found in the ovary, testis, and uterus.
1
Gene expression + Signal Transduction
Copper concentrates produced by mines are sold to smelters and refiners who treat the ore and refine the copper and charge for this service via treatment charges (TCs) and refining charges (RCs). The TCs are charged in US$ per tonne of concentrate treated and RCs are charged in cents per pound treated, denominated in U...
0
Metallurgy
There are at least three distinct mechanisms in which pRb can repress transcription of E2F-regulated promoters. Though these mechanisms are known, it is unclear which are the most important for the control of the cell cycle. E2Fs are a family of proteins whose binding sites are often found in the promoter regions of ge...
1
Gene expression + Signal Transduction
He joined the Baltimore Copper Smelting & Rolling Company in 1890, becoming vice president in 1895, and later, president of the company. Under his management, the company became one of the major copper producer of the United States. In 1928, the company merged with five other copper companies, to create the Revere Copp...
0
Metallurgy
Anaerobic corrosion (also known as hydrogen corrosion) is a form of metal corrosion occurring in anoxic water. Typically following aerobic corrosion, anaerobic corrosion involves a redox reaction that reduces hydrogen ions and oxidizes a solid metal. This process can occur in either abiotic conditions through a thermod...
0
Metallurgy
The protein encoded by this gene mediates transcriptional control by interaction with the Krüppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family...
1
Gene expression + Signal Transduction
An electric arc furnace used for steelmaking consists of a refractory-lined vessel, usually water-cooled in larger sizes, covered with a retractable roof, and through which one or more graphite electrodes enter the furnace. The furnace is primarily split into three sections: * the shell, which consists of the sidewalls...
0
Metallurgy
For a given stress profile and temperature, the point lies in a particular "deformation field". If the values place the point near the center of a field, it is likely that the primary mechanism by which the material will fail, i.e.: the type and rate of failure expected, grain boundary diffusion, plasticity, Nabarro–He...
0
Metallurgy
Three out of 10 advanced colorectal tumors had mutations leading to premature termination of the SFRP1 translation product. The mutations were two single-base deletions (26delG and 67delG) and a single-base change (G450A), which generates an in-frame stop codon. These three mutations were found within the first exon,...
1
Gene expression + Signal Transduction
Thousands of residents assembled to pay respects to Tom at his funeral filling the south end of Stockton High Street and the entire length of Bridge Road. His funeral procession, was four deep and numbered about two thousand people – an unusual turnout for a 40 year old industrialist and engineer.
0
Metallurgy
A galvanic cell or voltaic cell, named after the scientists Luigi Galvani and Alessandro Volta, respectively, is an electrochemical cell in which an electric current is generated from spontaneous oxidation–reduction reactions. A common apparatus generally consists of two different metals, each immersed in separate beak...
0
Metallurgy
TLRs are present in vertebrates as well as invertebrates. Molecular building blocks of the TLRs are represented in bacteria and in plants, and plant pattern recognition receptors are well known to be required for host defence against infection. The TLRs thus appear to be one of the most ancient, conserved components ...
1
Gene expression + Signal Transduction
There are other ways by which messages can be degraded, including non-stop decay and silencing by Piwi-interacting RNA (piRNA), among others.
1
Gene expression + Signal Transduction
The Dimetcote patent was approved in 1948 by the U.S. Patent Office. The owner of the patent is PPG Industries. Dimetcote, which was created to protect the surface of metal, could be coloured by being mixed with other paints.
0
Metallurgy
On June 17, 2004, a children's playground "City of Smiles" was opened in the park area of the plant. In the "City of Smiles" a sports area and playground, a railway for children, as well as a zoo were arranged, which contained a mouflon, a Bactrian camel, a pony, a donkey, a collared peccary, a raccoon, a red-headed du...
0
Metallurgy
In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal contr...
1
Gene expression + Signal Transduction
Calmodulin belongs to one of the two main groups of calcium-binding proteins, called EF hand proteins. The other group, called annexins, bind calcium and phospholipids such as lipocortin. Many other proteins bind calcium, although binding calcium may not be considered their principal function in the cell.
1
Gene expression + Signal Transduction
The nucleus accumbens (NAc) has a significant role in addiction. In the nucleus accumbens of mice, repeated cocaine exposure resulted in reduced TET1 messenger RNA (mRNA) and reduced TET1 protein expression. Similarly, there was a ~40% decrease in TET1 mRNA in the NAc of human cocaine addicts examined postmortem. As i...
1
Gene expression + Signal Transduction
Leaving alone remote antiquity and starting with Imperial Rome, the working of bronze, inspired probably by conquered Greece, is clearly seen. There are ancient bronze doors in the Temple of Romulus in the Roman Forum; others from the baths of Caracalla are in the Lateran Basilica, which also contains four fine gilt br...
0
Metallurgy
Another mechanism involving the structure of the 3′-UTR is called alternative polyadenylation (APA), which results in mRNA isoforms that differ only in their 3′-UTRs. This mechanism is especially useful for complex organisms as it provides a means of expressing the same protein but in varying amounts and locations. It ...
1
Gene expression + Signal Transduction
The majority of prostaglandin signaling occurs via GPCRs (see above) although certain prostaglandins activate nuclear receptors in the PPAR family. (See article eicosanoid receptors for more information).
1
Gene expression + Signal Transduction
The United States became interested in gas turbine development around 1905. From 1910-1915, austenitic ( γ phase) stainless steels were developed to survive high temperatures in gas turbines. By 1929, 80Ni-20Cr alloy was the norm, with small additions of Ti and Al. Although early metallurgists did not know it yet, they...
0
Metallurgy
The Wnt protein family includes a large number of cysteine-rich glycoproteins. The Wnt proteins activate signal transduction cascades via three different pathways, the canonical Wnt pathway, the noncanonical planar cell polarity (PCP) pathway, and the noncanonical Wnt/Ca pathway. Wnt proteins appear to control a wide r...
1
Gene expression + Signal Transduction
Curvibacter sp. is a gram-negative curved rod-formed bacterium which is the main colonizer of the epithelial cell surfaces of the early branching metazoan Hydra vulgaris. Sequencing the complete genome uncovered a circular chromosome (4.37 Mb), a plasmid (16.5 kb), and two operons coding each for an AHL (N-acyl-homoser...
1
Gene expression + Signal Transduction
Secreted by leukocytes, respectively fibroblasts, IFNα IFNβ together regulate antiviral immunity, cell proliferation and anti-tumor effects. In viral infection signalling pathway, either of IFNα or β binds to IFN receptor (IFNAR), composed of IFNAR1 and IFNAR2, immediately followed by the phosphorylation of STAT1, STAT...
1
Gene expression + Signal Transduction
Calcineurin inhibitors such as tacrolimus are used to suppress the immune system in organ allotransplant recipients to prevent rejection of the transplanted tissue.
1
Gene expression + Signal Transduction
Iron was never smelted by Native Americans, thus the New World never entered a proper "Iron Age" before European discovery, and the term is not used of the Americas. But there was limited use of native (unsmelted) iron ore, from magnetite, iron pyrite and ilmenite (iron–titanium), especially in the Andes (Chavin and Mo...
0
Metallurgy
The following inclusion types can also be found in aluminium alloys: alumina needles (AlO), nitrides (AlN), iron oxides (FeO), manganese oxides (MnO), fluorides (NaAlF, NaF, CaF, …), aluminium borides (AlB, AlB), borocarbides (AlCB). Bone ash (Ca(PO)) sometimes added to patch cracks in the trough can be found as inclus...
0
Metallurgy
*ATP2C1 NM_014382 *ATP5A1 NM_004046 Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, alpha *ATP5B NM_001686 *ATP5C1 NM_005174 *ATP5D NM_001687 Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, delta *ATP5F1 NM_001688 *ATP5G2 NM_005176 *ATP5G3 NM_001689 Homo sapiens A...
1
Gene expression + Signal Transduction
The Polevskoy Copper Smelting Plant (), also known as Polevaya or Poleva, was one of the major metallurgical facilities located in Polevskoy, in Sverdlovsk Oblast of Russia.
0
Metallurgy
TFB is recruited by another translation factor, TBP, after it recognizes the TATA box and bends the DNA so transcription can initiate. TFB stabilizes the TBP-DNA complex so that the proteins can recruit RNA Polymerase and melt the DNA via a yet-unknown mechanism. This opening of the DNA is not an energy-dependent proce...
1
Gene expression + Signal Transduction
Magnetation is the processing of iron ore tailings, the waste product of iron ore mines, to recover hematite. Crushed mine tailings are mixed with water to create a slurry; the slurry is then pumped through magnetic separation chambers to extract hematite. Commercial interest in this process stems from the possibility...
0
Metallurgy
Modern furnaces are equipped with an array of supporting facilities to increase efficiency, such as ore storage yards where barges are unloaded. The raw materials are transferred to the stockhouse complex by ore bridges, or rail hoppers and ore transfer cars. Rail-mounted scale cars or computer controlled weight hopper...
0
Metallurgy
The process by which the dosage and choice of flocculant are selected is called a jar test. The equipment used for jar testing consists of one or more beakers, each equipped with a paddle mixer. After the addition of flocculants, rapid mixing takes place, followed by slow mixing and later the sedimentation process. Sam...
0
Metallurgy
An outron is a nucleotide sequence at the 5' end of the primary transcript of a gene that is removed by a special form of RNA splicing during maturation of the final RNA product. Whereas intron sequences are located inside the gene, outron sequences lie outside the gene.
1
Gene expression + Signal Transduction
Cyclic AMP-dependent protein kinases (protein kinase A) are activated by the signal cascade originated by the activation of the G protein Gs by the LHCG-receptor. Activated Gs binds the enzyme adenylate cyclase and this leads to the production of cyclic AMP (cAMP). Cyclin AMP-dependent protein kinases are present as te...
1
Gene expression + Signal Transduction
Transcriptional regulation is one of the most common ways for an organism to alter gene expression. The use of activation and coactivation allows for greater control over when, where and how much of a protein is produced. This enables each cell to be able to quickly respond to environmental or physiological changes and...
1
Gene expression + Signal Transduction
Chromatin architectural remodeling is implicated in the process of cellular senescence, which is related to, and yet distinct from, organismal aging. Replicative cellular senescence refers to a permanent cell cycle arrest where post-mitotic cells continue to exist as metabolically active cells but fail to proliferate. ...
1
Gene expression + Signal Transduction
* BS 1881:204 Testing concrete. Recommendations on the use of electromagnetic covermeters * DGZfP:B2: Guideline “für Bewehrungsnachweis und Überdeckungsmessung bei Stahl- und Spannbeton” * DIN 1045: Guideline Concrete, reinforced and prestressed concrete structures * ACI Concrete Practices Non Destructive testing 228....
0
Metallurgy
One ancient process for extracting the silver from lead was cupellation. Lead was melted in a bone ash test or cupel and air blown across the surface. This oxidised the lead to litharge, and also oxidised other base metals present, the silver (and gold if present) remaining unoxidised. In the 18th century, the proces...
0
Metallurgy
Nucleoporins (Nups) are the main constituent proteins of NPCs and have been shown to play multiple roles in mediating several processes involved in gene gating. While it has been known that the nuclear periphery serves as the primary location for most heterochromatin, telomeric and centrosomal DNA, studies in the yeast...
1
Gene expression + Signal Transduction
Direct reduced iron (DRI), also called sponge iron, is produced from the direct reduction of iron ore (in the form of lumps, pellets, or fines) into iron by a reducing gas which either contains elemental carbon (produced from natural gas or coal) or hydrogen. When hydrogen is used as the reducing gas there are no gree...
0
Metallurgy
After the mRNA is completed and cleaved off at the poly-A signal sequence, the left-over (residual) RNA strand remains bound to the DNA template and the RNA polymerase II unit, continuing to be transcribed. After this cleavage, a so-called exonuclease binds to the residual RNA strand and removes the freshly transcribed...
1
Gene expression + Signal Transduction
Some genes involved in critical developmental processes contain multiple enhancers of overlapping function. Secondary enhancers, or "shadow enhancers", may be found many kilobases away from the primary enhancer ("primary" usually refers to the first enhancer discovered, which is often closer to the gene it regulates). ...
1
Gene expression + Signal Transduction
The results showed that global warming potential and acidification potential were the most significant environmental impacts. On average producing a tonne of steel emits 1.8 tonnes of . However, a steel mill using a top gas recycling blast furnace (TGRBF) producing a tonne of steel will emit 0.8 to 1.3 tonnes of depen...
0
Metallurgy
Xiang et al. found a new approach in inhibiting tumour growth and metastasis by simultaneously attacking both the tumour and its vasculature by a cytotoxic T cell (CTL) response against the survivin protein, which will later result in the activation of apoptosis in tumour cells. The idea and general principle behind hi...
1
Gene expression + Signal Transduction
SPIKE was developed by Ron Shamir's computational biology group in cooperation with the group of Yosef Shiloh, an Israel Prize recipient for his research in systems biology, and the group of Karen Avraham, a leading researcher of human deafness, all from Tel Aviv University.
1
Gene expression + Signal Transduction
Inside eukaryotic cells, there is a balance between the processes of translation and mRNA decay. Messages that are being actively translated are bound by ribosomes, the eukaryotic initiation factors eIF-4E and eIF-4G, and poly(A)-binding protein. eIF-4E and eIF-4G block the decapping enzyme (DCP2), and poly(A)-binding ...
1
Gene expression + Signal Transduction
A discussion of all mediator subunits is beyond the scope of this article, but details of one of the subunits are illustrative of the types of information that may be gathered for other subunits.
1
Gene expression + Signal Transduction
The Krupp–Renn process was a direct reduction steelmaking process used from the 1930s to the 1970s. It used a rotary furnace and was one of the few technically and commercially successful direct reduction processes in the world, acting as an alternative to blast furnaces due to their coke consumption. The Krupp-Renn pr...
0
Metallurgy
Each candidate CRM (cCRM) is cloned upstream of a reporter gene. Compared to traditional reporter assays, the main innovation is the use of fluorescence activated cell sorting (FACS) of dissociated cells, instead of microscopy, to screen for tissue-specific enhancers. This approach utilizes a two-marker system: in each...
1
Gene expression + Signal Transduction
It is known that Middle Minoan bronze work flourished as an independent native art. To the very beginning of this epoch belongs the largest sword of the age, found in the palace of Malia. It is a flat blade, 79 cm long, with a broad base and a sharp point; there is a gold and crystal hilt but no ornament on the blade. ...
0
Metallurgy
In-situ leaching is also called "solution mining". This process initially involves drilling of holes into the ore deposit. Explosives or hydraulic fracturing are used to create open pathways within the deposit for solution to penetrate into. Leaching solution is pumped into the deposit where it makes contact with the o...
0
Metallurgy
The termination of translation requires coordination between release factor proteins, the mRNA sequence, and ribosomes. Once a termination codon is read, release factors RF-1, RF-2, and RF-3 contribute to the hydrolysis of the growing polypeptide, which terminates the chain. Bases downstream the stop codon affect the a...
1
Gene expression + Signal Transduction
The van Arkel–de Boer process, also known as the iodide process or crystal-bar process, was the first industrial process for the commercial production of pure ductile titanium, zirconium and some other metals. It was developed by Anton Eduard van Arkel and Jan Hendrik de Boer in 1925. Now it is used in the production ...
0
Metallurgy
Culcheth Laboratories was a British metallurgical and nuclear research institute that researched the structural design of nuclear reactors and reactor pressure vessels in Culcheth, Cheshire, then in south Lancashire and now in the borough of Warrington.
0
Metallurgy
Signal transducer and activator of transcription 4 (STAT4) is a transcription factor belonging to the STAT protein family, composed of STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6. STAT proteins are key activators of gene transcription which bind to DNA in response to cytokine gradient. STAT proteins are a common ...
1
Gene expression + Signal Transduction
Pioneer factors can also actively affect transcription by directly opening up condensed chromatin in an ATP-independent process. This is a common trait of fork head box factors (which contain a winged helix DNA-binding domain that mimics the DNA-binding domain of the linker H1 histone), and NF-Y (whose NF-YB and NF-YC...
1
Gene expression + Signal Transduction
Despite being used in 90% of gold production: gold cyanidation is controversial due to the toxic nature of cyanide. Although aqueous solutions of cyanide degrade rapidly in sunlight, the less-toxic products, such as cyanates and thiocyanates, may persist for some years. The famous disasters have killed few people — hum...
0
Metallurgy
PTWA can be used to apply a coating to wear surfaces of engine or transmission components, serving as a plain bearing. For the cylinder bores of hypoeutectic aluminum-silicon alloy blocks, PTWA's main advantages over cast iron liners are reduced weight and cost. The thinner bore surface also allows for more compact bor...
0
Metallurgy
A number of lactose derivatives or analogs have been described that are useful for work with the lac operon. These compounds are mainly substituted galactosides, where the glucose moiety of lactose is replaced by another chemical group. * Isopropyl-β-D-thiogalactopyranoside (IPTG) is frequently used as an inducer of t...
1
Gene expression + Signal Transduction
The first high-volume product (> 5Mio actuators / year) is an automotive valve used to control low pressure pneumatic bladders in a car seat that adjust the contour of the lumbar support / bolsters. The overall benefits of SMA over traditionally-used solenoids in this application (lower noise/EMC/weight/form factor/pow...
0
Metallurgy
In viruses this phenomenon may be programmed to occur at particular sites and allows the virus to encode multiple types of proteins from the same mRNA. Notable examples include HIV-1 (human immunodeficiency virus), RSV (Rous sarcoma virus) and the influenza virus (flu), which all rely on frameshifting to create a prope...
1
Gene expression + Signal Transduction
Copper and its alloys are readily joined by mechanical techniques, such as crimping, staking, riveting, and bolting; or by bonding techniques, such as soldering, brazing and welding. Selection of the best joining technique is determined by service requirements, joint configuration, thickness of components, and alloy co...
0
Metallurgy
The Mountain Pass deposit is in a 1.4 billion-year-old Precambrian carbonatite intruded into gneiss. It contains 8% to 12% rare-earth oxides, mostly contained in the mineral bastnäsite. Gangue minerals include calcite, barite, and dolomite. It is regarded as a world-class rare-earth mineral deposit. The metals that can...
0
Metallurgy
From the 17th century onwards, several European travelers observed the steel manufacturing in South India, at Mysore, Malabar and Golconda. The word "wootz" appears to have originated as a mistranscription of wook; the Tamil language root word for the alloy is urukku. Anothertheory says that the word is a variation of ...
0
Metallurgy
[http://regulondb.ccg.unam.mx/menu/using_regulondb/tutorials/project_glossary/index.jsp Check the glossary for all definitions].
1
Gene expression + Signal Transduction
The use of EAFs allows steel to be made from a 100% scrap metal feedstock. This greatly reduces the energy required to make steel when compared with primary steelmaking from ores. Another benefit is flexibility: while blast furnaces cannot vary their production by much and can remain in operation for years at a time, E...
0
Metallurgy
Endonucleases are enzymes that recognise and cleave nucleic acid segments and they can be used to direct DNA assembly. Of the different types of restriction enzymes, the type II restriction enzymes are the most commonly available and used because their cleavage sites are located near or in their recognition sites. Henc...
1
Gene expression + Signal Transduction
Mutations to coactivator genes leading to loss or gain of protein function have been linked to diseases and disorders such as birth defects, cancer (especially hormone dependent cancers), neurodevelopmental disorders and intellectual disability (ID), among many others. Dysregulation leading to the over- or under-expres...
1
Gene expression + Signal Transduction
For a long time, it was normal procedure for a decommissioned blast furnace to be demolished and either be replaced with a newer, improved one, or to have the entire site demolished to make room for follow-up use of the area. In recent decades, several countries have realized the value of blast furnaces as a part of th...
0
Metallurgy
Geoksyur Oasis, located in the foothills of the Kopetdag, to the east of Altyndepe, is in the center of a cluster of tepes in the desert region on the northern Iranian border. It extends over an area of 12 ha. It is to the east of the city of Tedzhen. Even though in the Aneolithic Period (4th – early 3rd century BC), ...
0
Metallurgy
Scholars previously believed that sub-Saharan Africans either did not have a period of using copper until the nineteenth century (going from the Stone Age directly into the Iron Age), or that they started smelting iron and copper at the same time. Copper smelting is thought to have been practiced in Nubia, during the e...
0
Metallurgy
False brinelling was first mentioned by Almen in 1937. Almen found that wheel bearings were damaged before they were used by customers. Furthermore, he found that the bearings were more damaged for long-distance shipping of the cars and that the season of shipping also had an influence. The reason for the damaged beari...
0
Metallurgy
*Johnson, D. W., Johnson, R. T., & Smith, K. A. (1998). Cooperative learning returns to college what evidence is there that it works?. Change: the magazine of higher learning, 30(4), 26–35. *Smith, K.A. (2000). Going deeper: Formal small-group learning in large classes. In MacGregor, J., Cooper, J., Smith, K, and Robin...
0
Metallurgy
Sepro Tyre Driven Grinding Mills are designed for small and medium capacity grinding applications, specifically small tonnage plants, regrinding mills, reagent prep and lime slaking. Sepro Pneumatic Tyre Driven (PTD) mills provide an alternative to standard trunnion drive systems. The drive consists of multiple gears b...
0
Metallurgy
Culcheth is just over one mile north of junction 11 of the M62 motorway on the A574. It was administered by the Research and Development Branch of the United Kingdom Atomic Energy Authority (UKAEA).
0
Metallurgy
Polarized light (PL) is very useful when studying the structure of metals with non-cubic crystal structures (mainly metals with hexagonal close-packed (hcp) crystal structures). If the specimen is prepared with minimal damage to the surface, the structure can be seen vividly in cross-polarized light (the optic axis of ...
0
Metallurgy
In humans, cAMP works by activating protein kinase A (PKA, cAMP-dependent protein kinase), one of the first few kinases discovered. It has four sub-units two catalytic and two regulatory. cAMP binds to the regulatory sub-units. It causes them to break apart from the catalytic sub-units. The catalytic sub-units make th...
1
Gene expression + Signal Transduction
Auto Ejection Melt Spinning (AEMS) describes a type of melt spinning where ejection of the melt occurs as soon as it has liquefied, eliminating the need for a technician to manually control the flow rate, temperature, and/or release timing of the melt stream. This modification allows for a much higher ribbon consisten...
0
Metallurgy
Design parameters include type of mill, milling container, milling speed, milling time, type, size, and size distribution of the grinding medium, ball-to-powder weight ratio, extent of filling the vial, milling atmosphere, process control agent, temperature of milling, and the reactivity of the species.
0
Metallurgy
Scientists use a number of methods to study the complex structures and functions of the 3′ UTR. Even if a given 3′-UTR in an mRNA is shown to be present in a tissue, the effects of localization, functional half-life, translational efficiency, and trans-acting elements must be determined to understand the 3′-UTR's full ...
1
Gene expression + Signal Transduction