text stringlengths 66 377k |
|---|
Current standards and ethical landscape of engineered tissues—3D bioprinting perspective
Tissue engineering is an evolving multi-disciplinary field with cutting-edge technologies and innovative scientific perceptions that promise functional regeneration of damaged tissues/organs. Tissue engineered medical products (TE... |
Consequences of partially recessive deleterious genetic variation for the evolution of inversions suppressing recombination between sex chromosomes
The evolution of suppressed recombination between sex chromosomes is widely hypothesized to be driven by sexually antagonistic selection (SA), where tighter linkage betwee... |
Rectal Foreign Body: A Successful Removal at the Bedside and Detailing of a Stepwise Management
Objective:Management of emergency care Background:A rectal foreign body (RFB) can be stigmatizing for patients and present a dilemma for the treating physician. Removal can be challenging owing to the variety of objects int... |
Fast and strong amplifiers of natural selection
## Evolutionary graph theory
Here we formally define Moran Birth-death process on a population structure, the key quantities of fixation probability and timescale of fixation, and the notions of amplifiers and strong amplifiers.
Moran process on a population structure.... |
Endocrinology in the time of COVID-19
We provide guidance on prevention of adrenal crisis during the global COVID-19 crisis, a time with frequently restricted access to the usual level of healthcare. Patients with adrenal insufficiency are at an increased risk of infection, which may be complicated by developing an ad... |
Levels of selected oxidative stress markers in the vitreous and serum of diabetic retinopathy patients
[bib_ref] Antioxidant therapy for retinal disease, Kiang [/bib_ref] [bib_ref] Role of advanced glycation end products (AGEs) and oxidative stress in diabetic..., Yamagishi [/bib_ref] [bib_ref] Sepici-Dinçel A. Antio... |
‘Practical’ resources to support patient and family engagement in healthcare decisions: a scoping review
Background: Extensive literature exists on public involvement or engagement, but what actual tools or guides exist that are practical, tested and easy to use specifically for initiating and implementing patient and... |
Brunner's Gland Adenoma–An Uncommon Cause for Intussusception and Gastric Outlet Obstruction
Brunner's gland adenoma is extremely uncommon small bowel tumors with an incidence of ,0.01% and account for less than 1% of all gastrointestinal tumors. They are branched acinotubular glands found within the submucosal layer ... |
Peripheral perfusion index predicting prolonged ICU stay earlier and better than lactate in surgical patients: an observational study
Background: Peripheral perfusion index (PPI) is an indicator reflecting perfusion. Patients undergoing long time surgeries are more prone to hypoperfusion and increased lactate. Few stu... |
DNA-SIP based genome-centric metagenomics identifies key long-chain fatty acid-degrading populations in anaerobic digesters with different feeding frequencies
Fats, oils and greases (FOG) are energy-dense wastes that can be added to anaerobic digesters to substantially increase biomethane recovery via their conversion... |
Tuning multiple imputation by predictive mean matching and local residual draws
Background: Multiple imputation is a commonly used method for handling incomplete covariates as it can provide valid inference when data are missing at random. This depends on being able to correctly specify the parametric model used to im... |
Comparison of the Fractional Exhaled Nitric Oxide Levels in Adolescents at Three Schools Located Three Different Distances from a Large Steel Mill
Objectives. Exposure to ambient metals and air pollutants in urban environments has been associated with impaired lung health and inflammation in the lungs. Fractional exha... |
Pseudo and resistant hypertension: A chaotic perspective
Systemic blood pressure (BP) may oscillate for homeostatic needs (equilibrium by constancy) or just as shifts in other intrinsic and extrinsic variables known as allostatic changes. This transitory pressure often rises alerts physicians to out-of-control hyperte... |
Duffing oscillation-induced reversal of magnetic vortex core by a resonant perpendicular magnetic field
Nonlinear dynamics of the magnetic vortex state in a circular nanodisk was studied under a perpendicular alternating magnetic field that excites the radial modes of the magnetic resonance. Here, we show that as the ... |
Cost-effectiveness of rotavirus vaccination in children under five years of age in 195 countries: A meta-regression analysis
a b s t r a c tBackground: Rotavirus caused an estimated 151,714 deaths from diarrhea among children under 5 in 2019. To reduce mortality, countries are considering adding rotavirus vaccination ... |
Accuracy of toric intraocular lens implantation using automated vs manual marking
Background: Accurate alignment of toric intraocular lens (TIOL) to steep corneal astigmatic axis is important to achieve effective postoperative results. The authors compare the accuracy of astigmatism correction using automated and manu... |
Automated diagnosis of optical coherence tomography imaging on plaque vulnerability and its relation to clinical outcomes in coronary artery disease
This study sought to develop a deep learning-based diagnostic algorithm for plaque vulnerability by analyzing intravascular optical coherence tomography (OCT) images and ... |
Internal Carotid Artery Dissection in Brazilian Jiu-Jitsu
Carotid artery dissection is a significant cause of stroke in young patients. It may be asymptomatic and go undiagnosed, or minimal transient manifestations may follow, commanding a higher index of suspicion than ordinarily exists to avoid misdiagnosis. Reporte... |
Hypercoagulability in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD): Causes and Consequences
Citation: Tripodi, A.; Lombardi, R.; Primignani, M.; La Mura, V.; Peyvandi, F.; Fracanzani, A.L. Hypercoagulability in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD): Causes and Consequences.
# Introduction... |
Elevated peripheral expression of neuregulin-1 (NRG1) mRNA isoforms in clozapine-treated schizophrenia patients
Differential expression of neuregulin-1 (NRG1) mRNA isoforms and proteins has been reported in schizophrenia, primarily in post-mortem brain tissue. In this study, we examined 12 NRG1 SNPs, eight NRG1 mRNA i... |
Localizing evoked and induced responses to faces using magnetoencephalography
A rich pattern of responses in frequency, time and space are known to be generated in the visual cortex in response to faces. Recently, a number of studies have used magnetoencephalography (MEG) to try to record these responses non-invasivel... |
Transient Eye Shortening During Reading Text With Inverted Contrast: Effects of Refractive Error and Letter Size
Citation: Swiatczak B, Schaeffel F. Transient eye shortening during reading text with inverted contrast: Effects of refractive error and letter size. Transl Vis Sci Technol. 2022;11(4):17, https://doi.org/1... |
A medical peer-delivered intervention comprising brief motivational interviewing via instant-messaging interaction to reduce drug misuse among youth in Hong Kong: A protocol for a randomised controlled trial
Aims: Youth are frequently exposed to drugs, and most youth who misuse drugs are reluctant to seek help from se... |
Effects of antidiabetic drugs on epicardial fat
cytes with pathophysiological properties similar to those of visceral fat, located in the space between the myocardial muscle and the pericardial sac. When compared with subcutaneous adipose tissue, visceral adipocytes show higher metabolic activity, lipolysis rates, inc... |
Sarcopenia in Patients With Parkinson's Disease: A Systematic Review and Meta-Analysis
Background: Parkinson's disease (PD) and sarcopenia are two common diseases in aging people. To date, the prevalence of sarcopenia in PD patients and the relationship between clinical features and sarcopenia in PD patients are not c... |
Injection Site Reaction to Extended-Release Buprenorphine (Sublocade®) for Opioid Use Disorder Fourteen Days after Administration
# Introduction
In recent years, treatment options for Opioid Use Disorder (OUD) have grown to encompass a host of medications with various treatment formulations. Buprenorphine, a mainsta... |
Expression and Purification of Integral Membrane Fatty Acid Desaturases
Fatty acid desaturase enzymes perform dehydrogenation reactions leading to the insertion of double bonds in fatty acids, and are divided into soluble and integral membrane classes. Crystal structures of soluble desaturases are available; however, ... |
The disease burden attributable to 18 occupational risks in China: an analysis for the global burden of disease study 2017
Background: China has more than 18% of the global population and over 770 million workers. However, the burden of disease attributable to occupational risks is unavailable in China. We aimed to es... |
Medication-overuse headache: a widely recognized entity amidst ongoing debate
Medication overuse in primary headache disorders is a worldwide phenomenon and has a role in the chronification of headache disorders. The burden of disease on individuals and societies is significant due to high costs and comorbidities. In ... |
Evaluation of the feasibility of explainable computer-aided detection of cardiomegaly on chest radiographs using deep learning
We examined the feasibility of explainable computer-aided detection of cardiomegaly in routine clinical practice using segmentation-based methods. Overall, 793 retrospectively acquired posteri... |
Accessibility of pediatric inpatient services in Japan
In Japan, all citizens are covered by the national insurance system. Children's medical expenses are subsidized by local government co-payments. This removed most economic barriers to visiting medical facilities, geographical obstacles to pediatric medical service... |
The positive effect of mother-performed infant massage on infantile eczema and maternal mental state: A randomized controlled trial
# Introduction
Eczema, also known as atopic eczema or atopic dermatitis, is a chronic relapsing inflammatory dermatosis characterized by pruritus, xerosis and a close association with i... |
Evaluation of anti-cancer and anti-covid-19 properties of cationic pentapeptide Glu-Gln-Arg-Pro-Arg, from rice bran protein and its d-isomer analogs through molecular docking simulations
A B S T R A C TBioactive peptides derived from food proteins are becoming increasingly popular due to the growing awareness of their... |
Durable Response of Human Epidermal Growth Factor Receptor-2-Positive Gastric Adenosquamous Carcinoma to Trastuzumab-Based Chemotherapy
# Introduction
Adenosquamous carcinoma (ASC) of the stomach is a rare malignancy, accounting for <1% of all gastric carcinomas [bib_ref] p53, p16 and RB expression in adenosquamous ... |
Consensus on Perioperative Transesophageal Echocardiography of the Brazilian Society of Anesthesiology and the Department of Cardiovascular Image of the Brazilian Society of Cardiology
Through the Life Cycle of Intraoperative Transesophageal Echocardiography (ETTI/SBA) the Brazilian Society of Anesthesiology, together... |
Reduction in Pseudomonas aeruginosa sputum density during a cystic fibrosis pulmonary exacerbation does not predict clinical response
Background: Pulmonary exacerbations (PEx) are critical events in cystic fibrosis (CF), responsible for reduced quality of life and permanent loss of lung function. Approximately 1/4 of ... |
Cost-Effective Control of Plant Disease When Epidemiological Knowledge Is Incomplete: Modelling Bahia Bark Scaling of Citrus
## Symbol
Description
[formula] Value/Definition t Time since initial planting - S(t) Number of susceptible plants - E(t) [/formula]
Number of exposed plants -
[formula] I(t) Number of infect... |
Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study
Previous evidence supports the important role that oxidative stress (OxS) plays in metabolic syndrome (MetS)-related manifestations. We determined the relationship between the number of MetS components and the degree of O... |
Genetic and environmental causes of variation in epigenetic aging across the lifespan
Background: DNA methylation-based biological age (DNAm age) is an important biomarker for adult health. Studies in specific age ranges have found widely varying results about its genetic and environmental causes of variation. However... |
Practical aspects of protein co-evolution
Co-evolution is a fundamental aspect of Evolutionary Theory. At the molecular level, co-evolutionary linkages between protein families have been used as indicators of protein interactions and functional relationships from long ago. Due to the complexity of the problem and the ... |
Progress and Prospects of Nanocellulose-Based Membranes for Desalination and Water Treatment
# Introduction
The growing global population together with the natural water resource depletion can increase the freshwater requirement seven-fold [bib_ref] Nanoparticles in Reverse Osmosis Membranes for Desalination: A Stat... |
The spatial separation of processing and transport functions to the interior and periphery of the Golgi stack
It is unclear how the two principal functions of the Golgi complex, processing and transport, are spatially organized. Studying such spatial organization by optical imaging is challenging, partially due to the... |
Evaluation of Antioxidant, Antidiabetic and Anticholinesterase Activities of Smallanthus sonchifolius Landraces and Correlation with Their Phytochemical Profiles
The present study aimed to investigate the phytochemical profile of leaf methanol extracts of fourteen Smallanthus sonchifolius (yacon) landraces and their a... |
Volumetric Assessment of the Frontal Sinus in Female Adolescents and Its Relationship with Craniofacial Morphology and Orthodontic Treatment: A Pilot Study
# Introduction
The paranasal sinuses, the hollow spaces in the craniofacial bones around the nose, are air-filled cavities within the frontal, ethmoidal, sphenoi... |
Development and tracking of central patterns of subcutaneous fat of rural South African youth: Ellisras longitudinal study
Background: Individuals grow and accumulate central patterns of body fat into the diseases they will suffer from as older adults. The need to elicit the development and tracking of central pattern... |
A boy with developmental delay and mosaic supernumerary inv dup(5)(p15.33p15.1) leading to distal 5p tetrasomy – case report and review of the literature
Background: With only 11 patients reported, 5p tetrasomy belongs to rare postnatal findings. Most cases are due to small supernumerary marker chromosomes (sSMCs) or ... |
A functional SNP regulates E-cadherin expression by dynamically remodeling the 3D structure of a promoter-associated non-coding RNA transcript
Transcription of E-cadherin, a tumor suppressor which plays critical roles in cell adhesion and the epithelial-mesenchymal transition, is regulated by a promoter-associated non... |
Atypical femoral fracture as the cause of greater trochanteric pain syndrome – a case report
Greater trochanteric pain syndromeLateral hip pain Magnetic resonance imaging Looser zone a b s t r a c t Greater trochanteric pain syndrome may be caused by atypical femoral fractures, and this should be taken into considerat... |
Epidemiology of diabetic retinopathy and maculopathy in Africa: a systematic review
Aim To summarize findings from studies reporting the prevalence and incidence of diabetic retinopathy and diabetic maculopathy in African countries in light of the rising prevalence of diabetes mellitus.Methods Using a predefined searc... |
Case Report: A case of radioactive iodine-refractory thyroid cancer accompanying cervical lymph node metastasis treated with US-guided RFA combined with 125I seed implantation
Background: Local control of metastases is critical to improving the life quality of patients with radioactive iodine-refractory (RAIR) thyroid... |
A rapidly growing mature mediastinal teratoma with a testicular epidermoid cyst and familial Mediterranean fever
A B S T R A C TAnterior mediastinal teratomas are common and are generally characterized as slow growing tumors. Very few reports documenting rapidly growing tumors exist. Here, we describe a case of a matu... |
Evaluation of 3‐ and 4‐Phenoxybenzamides as Selective Inhibitors of the Mono‐ADP‐Ribosyltransferase PARP10
## General procedures
General Procedure A (GP A) -for the syntheses of compounds C, G, and K: In a sealed Schlenk tube, the 4-bromo-substituted arene (10 mmol) and the respective phenole derivative (10 mmol) we... |
Mechanical determinants of chromatin topology and gene expression
The compaction of linear DNA into micrometer-sized nuclear boundaries involves the establishment of specific three-dimensional (3D) DNA structures complexed with histone proteins that form chromatin. The resulting structures modulate essential nuclear p... |
The ethnic distribution of sickle cell disease in Sudan
Sickle cell disease (SCD) is one of the most common inherited disorders of haemoglobin in Africa and it is expected that sickle cell trait varies in frequency in different areas in Sudan. An extensive literature search was carried out accessing the US National Li... |
Impact of a school-based intervention on nutritional education and physical activity in primary public schools in Chile (KIND) programme study protocol: cluster randomised controlled trial
Background: Chile has suffered a fast increase in childhood obesity in the last 10 years. As a result, several school programmes h... |
Cardiac Imaging and Management of Prosthetic Valve Candida Parapsilosis Endocarditis
# Introduction
Fungal infective endocarditis (IE) is a rare and serious form of IE with mortality rates up to 50% [bib_ref] Fungal endocarditis, Yuan [/bib_ref]. Typical risk factors include prosthetic valve implantation, cardiac im... |
Contrecoup Extradural Hematoma Without Fracture: A Case Report and Review of Literature
Extradural hemorrhages are commonly seen in coup head injuries, rarely seen in contrecoup head injuries. Acute extradural hemorrhage in the coup head injuries associated with a fracture is common, but the incidence of acute contrec... |
Rouse model with transient intramolecular contacts on a timescale of seconds recapitulates folding and fluctuation of yeast chromosomes
DNA folding and dynamics along with major nuclear functions are determined by chromosome structural properties, which remain, thus far, elusive in vivo. Here, we combine polymer model... |
Concurrent Acute Monoblastic Leukemia and Multiple Myeloma in a 66-Year-Old Chemotherapy-Naive Woman
Concurrent acute myeloid leukemia (AML) and multiple myeloma (MM) is rare, more so in chemotherapy-naive patients. Concurrent occurrence of these two malignancies portends poor prognosis. Although anthracycline-based A... |
Toxin yet not toxic: Botulinum toxin in dentistry
Paracelsus contrasted poisons from nonpoisons, stating that ''All things are poisons, and there is nothing that is harmless; the dose alone decides that something is a poison". Living organisms, such as plants, animals, and microorganisms, constitute a huge source of p... |
Effect of light-curing units in shear bond strength of metallic brackets: an in vitro study
bjectives: To determine the influence of the light curing units on the shear bond strength of orthodontic brackets. Material and Methods: Seventy-two premolars were divided into six groups (n=12): Group I: brackets bonded with ... |
Rpn (YhgA-Like) Proteins of Escherichia coli K-12 and Their Contribution to RecA-Independent Horizontal Transfer
Bacteria use a variety of DNA-mobilizing enzymes to facilitate environmental niche adaptation via horizontal gene transfer. This has led to real-world problems, like the spread of antibiotic resistance, yet... |
Organizing pneumonia as the first manifestation of anti-synthetase syndrome
Background: Anti-synthetase syndrome associated interstitial lung disease can occur either simultaneously, before, or after the development of polymyositis/dermatomyositis. Histology of interstitial lung disease can be nonspecific interstitial... |
The role of microRNAs in respiratory viral infection: friend or foe?
S U M M A RYMicroRNAs (miRNAs) have emerged as a class of regulatory RNAs in host-pathogen interactions. Aberrant miRNA expression seems to play a central role in the pathology of several respiratory viruses, promoting development and progression of ... |
Efficacy and safety of fixed-dose combination therapy with olmesartan medoxomil and rosuvastatin in Korean patients with mild to moderate hypertension and dyslipidemia: an 8-week, multicenter, randomized, double-blind, factorial-design study (OLSTA-D RCT: OLmesartan rosuvaSTAtin from Daewoong)
# Introduction
The coe... |
COVID-19–Associated Bone Marrow Necrosis—A Case Report
# Introduction
The novel coronavirus disease 2019 (COVID-19 pneumonia) patients typically present with fever, shortness of breath, and cough. However, musculoskeletal complaints are seldom encountered as red flags. Here, we report the first presumptive case of C... |
Remarkable hexafunctional anion receptor with operational urea-based inner cleft and thiourea-based outer cleft: Novel design with high-efficiency for sulfate binding
The recognition of anions by designed receptors has attracted much attention in recent days. In particular, the selective binding of sulfate with artifi... |
Major histocompatibility complex (MHC) class II alleles, haplotypes and epitopes which confer susceptibility or protection in systemic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases and 1000 controls
Objective To determine human leucocyte antigenclass II (HLA-class II) (DRB1, DQB1, DQA1 and... |
Biorefinery of Biomass of Agro-Industrial Banana Waste to Obtain High-Value Biopolymers
On a worldwide scale, food demand is increasing as a consequence of global population growth. This makes companies push their food supply chains' limits with a consequent increase in generation of large amounts of untreated waste t... |
Spermine and Citrate as Metabolic Biomarkers for Assessing Prostate Cancer Aggressiveness
Separating indolent from aggressive prostate cancer is an important clinical challenge for identifying patients eligible for active surveillance, thereby reducing the risk of overtreatment. The purpose of this study was to assess... |
The cost-effectiveness of hospital-based telephone coaching for people with type 2 diabetes: a 10 year modelling analysis
Background: Type 2 diabetes (T2DM) is a burdensome condition for individuals to live with and an increasingly costly condition for health services to treat. Cost-effective treatment strategies are ... |
Cortical gyrification is abnormal in children with prenatal alcohol exposure
A B S T R A C TObjectives: Prenatal alcohol exposure (PAE) adversely affects early brain development. Previous studies have shown a wide range of structural and functional abnormalities in children and adolescents with PAE. The current study ... |
Green Tea, Intermittent Sprinting Exercise, and Fat Oxidation
Fat oxidation has been shown to increase after short term green tea extract (GTE) ingestion and after one bout of intermittent sprinting exercise (ISE). Whether combining the two will result in greater fat oxidation after ISE is undetermined. The aim of the... |
Pediatric Veno-Veno Extracorporeal Membrane Oxygenation Rescue From Carbon Monoxide Poisoning
Background: Carbon monoxide poisoning affects approximately 5000children per year and can be challenging to diagnose and treat (Pediatr Emerg Med Pract. 2016;13:1-24). It is in the differential diagnosis of a patient presente... |
Late evolution of arrhythmogenic cardiomyopathy in patients with initial presentation as idiopathic ventricular fibrillation
# Introduction
Arrhythmogenic cardiomyopathy (ACM), also known as arrhythmogenic right ventricular dysplasia/cardiomyopathy, is an inheritable heart muscle disorder in which sudden cardiac dea... |
Accuracy of electrocardiographic criteria for atrial enlargement: validation with cardiovascular magnetic resonance
Background: Anatomic atrial enlargement is associated with significant morbidity and mortality. However, atrial enlargement may not correlate with clinical measures such as electrocardiographic (ECG) cri... |
Multiple structure alignment and consensus identification for proteins
Background: An algorithm is presented to compute a multiple structure alignment for a set of proteins and to generate a consensus (pseudo) protein which captures common substructures present in the given proteins. The algorithm represents each prot... |
Health Needs and Their Relationship with Life Expectancy in People with and without Intellectual Disabilities in England
# Introduction
Addressing the burden of health inequalities is now a global priority. Strategies to reduce these inequalities tend to focus on the most vulnerable, such as people living with disab... |
The Impacts of Prenatal Mental Health Issues on Birth Outcomes during the COVID-19 Pandemic: A Scoping Review
# Introduction
Adverse birth outcomes, including low birth weight, preterm birth and small for gestational age, are the leading causes of infant morbidity and mortality [bib_ref] Antenatal Depressive Symptom... |
One case of wrist cyst rupture with nerve and blood vessel compression
Introduction and importance: Tendon sheath cysts are mostly located around the joint capsule and tendon sheath, which often occur in the wrist, ankle, and wrist back(O'Valle et al., 2014;Nguyen et al., 2004 [1, 2]). The palmar side of the wrist is ... |
Posterior reversible encephalopathy syndrome in a patient with mixed connective tissue disease: a case report
Background: Posterior reversible encephalopathy is a syndrome highly associated with hypertension and cytotoxic therapy. The syndrome typically presents with headache, visual abnormality, seizures and characte... |
System‐level metabolic modeling facilitates unveiling metabolic signature in exceptional longevity
## | introduc ti on
Population aging is an increasingly urgent issue confronting many countries worldwide [bib_ref] Measuring population ageing: An analysis of the Global Burden of Disease Study, Chang [/bib_ref]. As m... |
Dominant mutations in ITPR3 cause Charcot‐Marie‐Tooth disease
Objective: ITPR3, encoding inositol 1,4,5-trisphosphate receptor type 3, was previously reported as a potential candidate disease gene for Charcot-Marie-Tooth neuropathy. Here, we present genetic and functional evidence that ITPR3 is a Charcot-Marie-Tooth d... |
Using Microdosing to Induct Patients Into a Long-Acting Injectable Buprenorphine Depot Medication in Low Threshold Community Settings: A Case Study
Healthcare innovation has never been more important as it is now when the world is facing up to the unprecedented challenges brought by the COVID-19 pandemic. Within addic... |
Prognostic Value and Clinicopathological Differences of HIFs in Colorectal Cancer: Evidence from Meta-Analysis
Background: The prognostic value of HIFs in colorectal cancer was evaluated in a large number of studies, but the conclusions were inconclusive. Meanwhile, clinicopathologic differences of HIF-1a and HIF-2a w... |
Reirradiation of pulmonary artery intimal sarcoma: A case report
This is an open access article under the terms of the Creat ive Commo ns Attri butio n-NonCo mmercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial pur... |
Impact of Interspecific Hybridization between Crops and Weedy Relatives on the Evolution of Flowering Time in Weedy Phenotypes
Background: Like conventional crops, some GM cultivars may readily hybridize with their wild or weedy relatives. The progressive introgression of transgenes into wild or weedy populations thus... |
Universal thermal climate index associations with mortality, hospital admissions, and road accidents in Bavaria
When meteorological conditions deviate from the optimal range for human well-being, the risks of illness, injury, and death increase, and such impacts are feared in particular with more frequent and intense ... |
The relationship between IL-6 levels and the angiographic severity of coronary artery disease following percutaneous coronary intervention in acute coronary syndrome patients
Background: The present investigation was developed for the exploration of the association between IL-6 levels and acute coronary syndrome (ACS)... |
Bone Infarcts and Tumorigenesis—Is There a Connection? A Mini-Mapping Review
Citation: Konarski, W.; Poboży, T.; Hordowicz, M.;Śliwczyński, A.; Kotela, I.; Krakowiak, J.; Kotela, A.
# Introduction
Bone infarct, also known as aseptic or avascular necrosis of the bone (AVN), is characterized by osteocytes and bone marr... |
Advancements in stem cells treatment of skeletal muscle wasting
† These authors have contributed equally to this work.Muscular dystrophies (MDs) are a heterogeneous group of inherited disorders, in which progressive muscle wasting and weakness is often associated with exhaustion of muscle regeneration potential. Altho... |
Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes
Infection by Group A Streptococcus pyogenes (GAS)is a leading cause of severe invasive disease in humans, including streptococcal toxic shock syndrome and necrotizing fasciitis. GAS infections lead to nearly 163,000 annual de... |
Predicting Glycemic Index and Glycemic Load from Macronutrients to Accelerate Development of Foods and Beverages with Lower Glucose Responses
Low glycemic index (GI) and/or low glycemic load (GL) are associated with decreased risks of type-2 diabetes and cardiovascular disease. It is therefore relevant to consider GI ... |
Many important natural products are produced by multidomain nonribosomal peptide synthetases (NRPSs) 1-4 . During synthesis, intermediates are covalently bound to integrated carrier domains and transported to neighboring catalytic domains in an assembly line fashion 5 . Understanding the structural basis for catalysis ... |
Can native clonal moso bamboo encroach on adjacent natural forest without human intervention?
Native species are generally thought not to encroach on adjacent natural forest without human intervention. However, the phenomenon that native moso bamboo may encroach on surrounding natural forests by itself occurred in Chi... |
Exposure‐Response Characterization of Tofacitinib Efficacy in Moderate to Severe Ulcerative Colitis: Results From Phase II and Phase III Induction and Maintenance Studies
Tofacitinib is an oral small molecule JAK inhibitor for the treatment of ulcerative colitis. Relationships between plasma tofacitinib concentration ... |
The Online Bioinformatics Resources Collection at the University of Pittsburgh Health Sciences Library System—a one-stop gateway to online bioinformatics databases and software tools
To bridge the gap between the rising information needs of biological and medical researchers and the rapidly growing number of online bi... |
Association between antenatal care visit and preterm birth: a cohort study in rural Bangladesh
Background Strengthening the antenatal care programme is suggested as one of the public health strategies to reduce preterm birth burden at a population level. However, the evidence so far available is inconclusive. Objectiv... |
Peritoneal Tuberculosis during Infliximab Treatment in a Patient with Ulcerative Colitis Despite a Negative Quantiferon Test
Citation: Colombo, A.; Giuffrè, M.; Crocè, L.S.; Venturini, S.; Sablich, R. Peritoneal Tuberculosis during Infliximab Treatment in a Patient with Ulcerative Colitis Despite a Negative Quantifero... |
WASH Upgrades for Health in Amhara (WUHA): study protocol for a cluster-randomised trial in Ethiopia
# Introduction background
Trachoma, caused by ocular chlamydial infection, is the leading infectious cause of blindness worldwide and a focus of elimination efforts. [bib_ref] Global causes of blindness and distance ... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.