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The geometric phase controls ultracold chemistry
The geometric phase is shown to control the outcome of an ultracold chemical reaction. The control is a direct consequence of the sign change on the interference term between two scattering pathways (direct and looping), which contribute to the reactive collision proces... |
Nanomaterials-Based Novel Immune Strategies in Clinical Translation for Cancer Therapy
Citation: Wahab, S.; Ghazwani, M.; Hani, U.; Hakami, A.R.; Almehizia, A.A.; Ahmad, W.; Ahmad, M.Z.; Alam, P.; Annadurai, S.
# Introduction
Cancer evolves and spreads due to the inability of the host immune system (IS), which is one... |
Releasing the brakes: a case report of pulmonary arterial hypertension induced by immune checkpoint inhibitor therapy
Immune checkpoint inhibitors successfully treat various malignancies by inducing an immune response to tumor cells. However, their use has been associated with a variety of autoimmune disorders, such a... |
Antiferromagnetic domain wall as spin wave polarizer and retarder
Lan et al. reports a theoretical study on the spin-wave (SW) propagation through an antiferromagnetic domain wall (DW), which is subject to the Dzyaloshinskii-Moriya interaction (DMI). The authors find that the in-plane and out-of-plane SW modes experie... |
The proteomics approach to find biomarkers in gastric cancer.
# Introduction
Gastric cancer is the most common cancer in Korea. It is an unfortunate reality for many Koreans. It has been a very serious disease and is naturally resistant to many anticancer drugs, so the results after surgery and chemotherapy have bee... |
Sickness Presenteeism as a Link between Long Working Hours and Employees’ Outcomes: Intrinsic and Extrinsic Motivators as Resources
# Introduction
Sickness presenteeism (presenteeism hereafter) refers to situations where people still turn up at their jobs despite ill health that should prompt rest and absence from w... |
Externalizing problems in childhood and adolescence predict subsequent educational achievement but for different genetic and environmental reasons
Background: Childhood behavior problems predict subsequent educational achievement; however, little research has examined the etiology of these links using a longitudinal t... |
The Accumulation and Transformation of Heavy Metals in Sediments of Liujiang River Basin in Southern China and Their Threatening on Water Security
# Introduction
Rivers are vital channels of water resource regulation and storage; however, with the development of industry and agriculture, they have gradually become a... |
Dyadic parent–infant interaction patterns at 12 months: Exploring dyadic parent–infant gender compositions
This study investigates differences in dyadic mother-infant and father-infant interaction patterns at infant age 12 months, and the relation between different parent-infant gender compositions and the dyadic inte... |
Expanded CUG repeats in DMPK transcripts adopt diverse hairpin conformations without influencing the structure of the flanking sequences
[formula] U A G G C C U G G C C U A U C G G A G G C G C U U U C C C U G C U C C U G U U C G C C G U U G U U C U G U C U C G U G C C G C C G C C C U G G G C U G C A U U G G G U U G G... |
Species Tree Inference Methods Intended to Deal with Incomplete Lineage Sorting Are Robust to the Presence of Paralogs
Many recent phylogenetic methods have focused on accurately inferring species trees when there is gene tree discordance due to incomplete lineage sorting (ILS). For almost all of these methods, and fo... |
Pneumocystis jirovecii diagnosed by next-generation sequencing of bronchoscopic alveolar lavage fluid: A case report and review of literature
BACKGROUNDThe advent of molecular targeted agents and immune checkpoint inhibitors has greatly improved the treatment of advanced renal cell carcinoma (RCC), thus significantly ... |
A Parathyroid Adenoma: Benign Disease Presenting with Hyperparathyroid Crisis
Hyperparathyroid crisis is a rare manifestation of parathyroid disease. We present the case of a 53-year-old gentleman with a review of the current literature. He presented in acute renal failure with epigastric pain and vomiting. His serum-... |
Microcurrent Stimulation Triggers MAPK Signaling and TGF-β1 Release in Fibroblast and Osteoblast-Like Cell Lines
Wound healing constitutes an essential process for all organisms and involves a sequence of three phases. The disruption or elongation of any of these phases can lead to a chronic or non-healing wound. Elec... |
Quantifying Positional Isomers (QPI) by Top-Down Mass Spectrometry
CorrespondenceGraphical Abstract 5 17 26 70 −2 0 2 0 1 C C AC AC AC Modifications Sequence position p-val: 0.97 (n.s.) Ratio (log2) 0 2 4 6 Expected ratio Detected ratio (log2) 1 : 1 4 : 1 1 6 : 1 6 4 : 1 r.a.scheltema@uu.nlIn BriefHere we determine th... |
Effects of short-term fructooligosaccharide intake on equol production in Japanese postmenopausal women consuming soy isoflavone supplements: a pilot study
Background: Recent studies suggest that some of the clinical effectiveness of soy or daidzein, which is a type of isoflavone, may be attributed to a person's abili... |
Dynamical time-reversal symmetry breaking and photo-induced chiral spin liquids in frustrated Mott insulators
The search for quantum spin liquids in frustrated quantum magnets recently has enjoyed a surge of interest, with various candidate materials under intense scrutiny. However, an experimental confirmation of a g... |
Environmental regulation of carbon isotope composition and crassulacean acid metabolism in three plant communities along a water availability gradient
Expression of crassulacean acid metabolism (CAM) is characterized by extreme variability within and between taxa and its sensitivity to environmental variation. In this... |
Reaching the Challenging Diagnosis of Complicated Liver Hydatid Disease: A Single Institution’s Experience from an Endemic Area
Citation: Christodoulidis, G.; Samara, A.A.; Diamantis, A.; Floros, T.; Sgantzou, I.-K.; Karakantas, K.-S.; Zotos, P.-A.; Koutras, A.; Janho, M.B.; Tepetes, K. Reaching the Challenging Diagno... |
Analyzing the Effect of Time in Migration Measurement Using Georeferenced Digital Trace Data
Georeferenced digital trace data offer unprecedented flexibility in migration estimation. Because of their high temporal granularity, many migration estimates can be generated from the same data set by changing the definition ... |
The Study of Health-Related Fitness Normative Scores for Nepalese Older Adults
Physical fitness tests are important to maintain and promote the health status of people. The purpose of this study was to develop health-related fitness evaluation norms according to the age and gender of Nepalese older adults. One thousan... |
Minimally invasive devices for treating lower urinary tract symptoms in benign prostate hyperplasia: technology update
Benign prostatic hyperplasia (BPH) represents a spectrum of related lower urinary tract symptoms (LUTS). The cost of currently recommended medications and the discontinuation rate due to side effects ... |
Establishment of a Percutaneous Coronary Intervention Registry in Vietnam: Rationale and Methodology
Background:In lower-and middle-income countries across Asia there has been a rapid expansion and uptake of percutaneous coronary intervention (PCI). However, there has been limited routine collection of related data, p... |
Joint association of physical activity and overweight with subsequent psychotropic medication: a register-linked follow-up study among employees
Background: Physical activity level and overweight have shown associations with mental health problems but it is not known whether the risk of mental health problems due to o... |
Large-Scale Plantlet Conversion and Ex Vitro Transplantation Efficiency of Siberian Ginseng by Bioreactor Culture
To achieve large-scale low-cost ex vitro acclimatization of Siberian ginseng plants, heart-and torpedo-shaped secondary somatic embryos (SEs) induced from germinated SEs on agar medium were collected and t... |
LED Fluorescence Microscopy for the Diagnosis of Pulmonary Tuberculosis: A Multi-Country Cross-Sectional Evaluation
Background: The diagnosis of tuberculosis (TB) in resource-limited settings relies on Ziehl-Neelsen (ZN) smear microscopy. LED fluorescence microscopy (LED-FM) has many potential advantages over ZN smear... |
Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis
Edited by Ursula JakobProgranulin (PGRN) is a glycoprotein implicated in several neurodegenerative diseases. It is highly expressed in microglia and macrophages and can be secreted or delivered... |
Cytoplasmic vacuolation with endoplasmic reticulum stress directs sorafenib induced non-apoptotic cell death in hepatic stellate cells
The activated hepatic stellate cells (HSCs) are the major cells that secrete the ECM proteins and drive the pathogenesis of fibrosis in chronic liver disease. Targeting of HSCs by modu... |
Neural Pattern Classification Tracks Transfer-Appropriate Processing in Episodic Memory
The transfer-appropriate processing (TAP) account holds that episodic memory depends on the overlap between encoding and retrieval processing. In the current study, we employed multivariate pattern analysis (MVPA) of electroencepha... |
Association of Human Leukocyte Antigen Alleles and Nevirapine Hypersensitivity in a Malawian HIV-Infected Population
Background. The nonnucleoside reverse transcriptase inhibitor nevirapine is the cornerstone of treatment for human immunodeficiency virus (HIV) in many sub-Saharan African countries. However, nevirapine... |
A multicenter prospective, randomized, placebo-controlled phase II/III trial for preemptive acute graft-versus-host disease therapy
Acute graft-versus-host disease (aGvHD) contributes to about 50% of transplant-related mortality (non-relapse mortality) after allogeneic hematopoietic stem cell transplantation (HSCT). H... |
The unequal impact of the coronavirus pandemic: Evidence from seventeen developing countries
We recruited participants for the survey using paid advertisement posts on Facebook and Instagram. To be eligible to participate in the survey, participants had to be at least 18 years old. In each country, we targeted the soc... |
Streptovertimycins A–H, new fasamycin-type antibiotics produced by a soil-derived Streptomyces morookaense strain
Eight new fasamycin-type polyketides, streptovertimycins A-H (1−8), were isolated from soil-derived Streptomyces morookaense SC1169 cultivated on wheat grains. Their structures were established by extensiv... |
Smoking Mechanics and Impact on Smoking Cessation: Two Cases of Smoking Lapse Status Post Lung Transplantation
BACKGROUND:Smoking behavior includes mechanisms taken on by persons to adjust for certain characteristic changes of cigarettes. However, as lung function declines due to lung-specific diseases, it is unclear ... |
Low Serum Vitamin D in COVID-19 Patients Is Not Related to Inflammatory Markers and Patients’ Outcomes—A Single-Center Experience and a Brief Review of the Literature
Citation: Hut , anu, A.; Georgescu, A.M.; Voidȃzan, S.; Andrejkovits, A.V.; Negrea, V.; Dobreanu, M. Low
# Introduction
Vitamin D is a fat-soluble vita... |
Flexible transparent graphene/polymer multilayers for efficient electromagnetic field absorption
Thanks to its high electrical conductivity, a graphene plane presents a good shielding efficiency against GHz electromagnetic radiations. Several graphene planes separated by thin polymer spacers add their conductivities a... |
Successful atrial fibrillation ablation without pulmonary vein isolation utilizing focal impulse and rotor mapping in an atriopulmonary Fontan
# Introduction
Fontan palliation is designed to separate systemic and pulmonary circulations to ameliorate systemic hypoxemia and relieve ventricular volume overload in patie... |
Current status and recent advances in resection cavity irradiation of brain metastases
Despite complete surgical resection brain metastases are at significant risk of local recurrence without additional radiation therapy. Traditionally, the addition of postoperative whole brain radiotherapy (WBRT) has been considered ... |
The impact of doubling dairy or plant-based foods on consumption of nutrients of concern and proper bone health for adolescent females
Objective: To determine the effects of increasing plant-based foods v. dairy foods on energy and nutrients of concern in adolescent females via diet modelling exercises. Design: Data f... |
Drop the Needle; A Temperature Stable Oral Tablet Vaccine Is Protective against Respiratory Viral Pathogens
# Introduction
The recent pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) demonstrated that public health systems throughout the world were inadequately prepared to respond to a... |
Inhibitors of the Influenza A Virus M2 Proton Channel Discovered Using a High-Throughput Yeast Growth Restoration Assay
The M2 proton channel of the influenza A virus is the target of the anti-influenza drugs amantadine and rimantadine. The effectiveness of these drugs has been dramatically limited by the rapid spread... |
Talaromyces marneffei infection in a non-HIV non-endemic population
# Introduction
Talaromyces (Penicillium) marneffei is a dimorphic fungus and the only member in its genus known to be pathogenic to humans. It can cause both localized as well as overwhelming disseminated infection. T. marneffei is endemic to Southe... |
Reduced Prevalence of Oral Human Papillomavirus (HPV) 4 Years after Bivalent HPV Vaccination in a Randomized Clinical Trial in Costa Rica
Title:A double blind, controlled, randomized, phase III study of the efficacy of an HPV16/18 VLP vaccine in the prevention of advanced cervical intraepithelial neoplasia (CIN2, CIN3... |
Recent Advances in Multifunctional Mechanical–Chemical Superhydrophobic Materials
In recent years, biology-inspired superhydrophobic technology has attracted extensive attention and has been widely used in self-cleaning, anti-icing, oil-water separation, and other fields. However, the poor durability restricts its app... |
Effect of Interactions on the Nutrient Status of a Tropical Soil Treated with Green Manures and Inorganic Phosphate Fertilizers
Integrated nutrient management systems using plant residues and inorganic P fertilizers have high potential for increasing crop production and ensuring sustainability in the tropics, but thei... |
Effect of FAT1 gene expression on the prognosis of medulloblastoma in children
Background: It was reported that cloning human adipose atypical cadherin 1 (FAT1) has an effect on the prognosis of medulloblastoma (MB), while the conclusion still needs to be further proved. Therefore, this study attempted to explore the ... |
Model-based estimation of measures of association for time-to-event outcomes
Background: Hazard ratios are ubiquitously used in time to event applications to quantify adjusted covariate effects. Although hazard ratios are invaluable for hypothesis testing, other adjusted measures of association, both relative and abso... |
Richter Syndrome: From Molecular Pathogenesis to Druggable Targets
## Definition of richter syndrome
Richter Syndrome (RS) was reported for the first time by Maurice N. Richter as "reticular cell sarcoma" in 1928 [bib_ref] Generalized Reticular Cell Sarcoma of Lymph Nodes Associated with Lymphatic Leukemia, Richter ... |
Sentinel Listeriosis Surveillance in Selected Hospitals, China, 2013–2017
During 2013-2017, a total of 211 cases of listeriosis were reported by 64 sentinel hospitals in China to a national foodborne disease surveillance network. The average case-fatality rate was 31.2% for perinatal cases and 16.4% for nonperinatal c... |
Circadian rhythms of hemostatic factors in tetraplegia: a double-blind, randomized, placebo-controlled cross-over study of melatonin
Study design: This is a double-blind, randomized, placebo-controlled cross-over study of melatonin in complete tetraplegia. Objectives: Tetraplegic patients have an increased risk of ven... |
Electrocorticography reveals thalamic control of cortical dynamics following traumatic brain injury
The return of consciousness after traumatic brain injury (TBI) is associated with restoring complex cortical dynamics; however, it is unclear what interactions govern these complex dynamics. Here, we set out to uncover ... |
Plasma Amino Acid Profile in Patients with Aortic Dissection
[fig] Fig: S2 Permutation test plots (200 permutations) for all the PLS-DA score plots. A: Acute AD vs. [/fig]
[table] Table S1: Data for quality control samples. [/table]
|
Microsatellite instability in colorectal cancer
Colorectal cancer (CRC) is a heterogeneous disease that is caused by the interaction of genetic and environmental factors. Although it is one of the most common cancers worldwide, CRC would be one of the most curable cancers if it is detected in the early stages. Molecul... |
The scalability of common paradigms for assessment of cognitive function: A functional transcranial Doppler study
Cognitive paradigms induce changes in cerebral blood flow (CBF) associated with increased metabolic demand, namely neurovascular coupling (NVC). We tested the hypothesis that the effect of complexity and d... |
Improvements in productivity at paid work and within the household, and increased participation in daily activities after 24 weeks of certolizumab pegol treatment of patients with psoriatic arthritis: results of a phase 3 double-blind randomised placebo-controlled study
# Introduction
Psoriatic arthritis (PsA) is a ... |
Regulation of mRNA cap methylation
The 7-methylguanosine cap added to the 5 end of mRNA is essential for efficient gene expression and cell viability. Methylation of the guanosine cap is necessary for the translation of most cellular mRNAs in all eukaryotic organisms in which it has been investigated. In some experime... |
The associations between psychological distress and healthcare use in patients with non-cardiac chest pain: does a history of cardiac disease matter?
Background: Psychological distress such as somatization, fear of body sensations, cardiac anxiety and depressive symptoms is common among patients with non-cardiac chest... |
Gut microbiota as the key controllers of “healthy” aging of elderly people
Extrinsic factors, such as lifestyle and diet, are shown to be essential in the control of human healthy aging, and thus, longevity. They do so by targeting at least in part the gut microbiome, a collection of commensal microorganisms (microbio... |
Identifications and classifications of human locomotion using Rayleigh-enhanced distributed fiber acoustic sensors with deep neural networks
This paper reports on the use of machine learning to delineate data harnessed by fiber-optic distributed acoustic sensors (DAS) using fiber with enhanced Rayleigh backscattering ... |
Pleomorphic spermatic cord liposarcoma: A case report and review of management
a b s t r a c tLiposarcoma of the spermatic cord is very rare, representing about 7% of para testicular sarcomas. It is considered to be one of the highest malignancy grades.We present a case of a liposarcoma of the spermatic cord in a 45-y... |
Spatial arrangement of several flagellins within bacterial flagella improves motility in different environments
Bacterial flagella are helical proteinaceous fibers, composed of the protein flagellin, that confer motility to many bacterial species. The genomes of about half of all flagellated species include more than ... |
Primary uterine diffuse large B-cell lymphoma involving the urinary bladder with urinary cytology mimicking carcinomas: A case report
We report a rare case of a 69-year-old woman in whom diffuse large B-cell lymphoma (DLBCL) originated from the uterus and involved the urinary bladder. The cervical smears of the case m... |
Delineating the mechanisms and design principles of Caenorhabditis elegans embryogenesis using in toto high-resolution imaging data and computational modeling
a b s t r a c tThe nematode (roundworm) Caenorhabditis elegans is one of the most popular animal models for the study of developmental biology, as its invariant... |
Non-coding RNAs as potential biomarkers in osteosarcoma
Osteosarcoma (OS) is a primary solid malignant tumor that occurs most frequently in the metaphysis of long bones. More likely to happen to children and adolescents. OS has high mortality and disability rate. However, the etiology and pathogenesis of OS have not b... |
A case of bilateral persistent sciatic artery with unilateral aneurysm: An 18-year period of graft patency after excision of aneurysm
Background:A persistent sciatic artery (PSA) is a rare vascular anomaly with an estimated incidence of 0.02-0.04% and with a high rate of complications such as aneurysm formation, throm... |
Rehabilitation for the management of knee osteoarthritis using comprehensive traditional Chinese medicine in community health centers: study protocol for a randomized controlled trial
Background: It is becoming increasingly necessary for community health centers to make rehabilitation services available to patients wi... |
IL-14α as a Putative Biomarker for Stratification of Dry Eye in Primary Sjögren’s Syndrome
## Figure 1. a fabricated western blot image opened in imagej. the information along the top of the image indicates that the image is currently in 8-bit mode, using an inverting lut (look-up table). the inverting lut ensures t... |
National Mass Drug Administration Costs for Lymphatic Filariasis Elimination
Background: Because lymphatic filariasis (LF) elimination efforts are hampered by a dearth of economic information about the cost of mass drug administration (MDA) programs (using either albendazole with diethylcarbamazine [DEC] or albendazol... |
Transient Global Amnesia and Brain Tumour: Chance Concurrence or Aetiological Association? Case Report and Systematic Literature Review
# Introduction
Syndromes of transient amnesia may broadly be conceptualised as idiopathic, epileptic or psychological in origin. Although there are some clinical features which may ... |
Leveling the playing field: The utility of coronary artery calcium scoring in cardiovascular risk stratification in South Asians
# Introduction
South Asian (SA) individuals make up a diverse ethnic milieu of individuals that trace their roots back to the Southern part of Asia including the Indian subcontinent. The t... |
Actions of Two Bi-Articular Muscles of the Lower Extremity: A Review
The extremities of the human body contain several bi-articular muscles. The actions produced by muscles at the joints they cross are greatly influenced by joint moment arms and muscle length. These factors are dynamic and subject to change as joint a... |
Antimicrobial Activity of a Triple Antibiotic Combination Toward Ocular Pseudomonas aeruginosa Clinical Isolates
Citation: Mei JA, Johnson W, Kinn B, Laskey E, Nolin L, Bhamare P, Stalker C, Dunman PM, Wozniak RAF. Antimicrobial activity of a triple antibiotic combination toward ocular pseudomonas aeruginosa clinical ... |
Recurrent COVID‐19 pneumonia in the course of chemotherapy: Consequence of a weakened immune system?
[bib_ref] Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study, Tan [/bib_ref] [bib_ref] Renin-angiotensin-aldosterone system inhibitors in patients 198 with covid-19, Vaduganathan [/b... |
A Conceptual Framework for Planning Systemic Human Adaptation to Global Warming
Human activity is having multiple, inter-related effects on ecosystems. Greenhouse gas emissions persisting along current trajectories threaten to significantly alter human society. At 0.85 °C of anthropogenic warming, deleterious human im... |
Chlamydia trachomatis infection in a sample of northern Brazilian pregnant women: prevalence and prenatal importance
Pregnant women Neonatal infection Respiratory symptoms Polymerase chain reaction Brazil a b s t r a c t There are limited data regarding prevalence of Chlamydia trachomatis infection among northern Braz... |
Postoperative Adhesive Small Bowel Obstruction Presenting as Acute Urinary Retention
Postoperative adhesions are commonly seen after most abdominal surgeries. The majority of patients with intra-abdominal adhesions remain asymptomatic; however, some patients may develop symptoms ranging from mild abdominal pain to som... |
A Molecular Insight into Algal-Oomycete Warfare: cDNA Analysis of Ectocarpus siliculosus Infected with the Basal Oomycete Eurychasma dicksonii
Brown algae are the predominant primary producers in coastal habitats, and like land plants are subject to disease and parasitism. Eurychasma dicksonii is an abundant, and prob... |
Off-Label Use of Chloroquine and Hydroxychloroquine for COVID-19 Treatment in Africa Against WHO Recommendation
COVID-19 is continuing as a big challenge for the globe and several types of research are continued to find safe and effective treatment and preventive options. Although
# Introduction
## Chloroquine and h... |
Inhibition of translation termination by small molecules targeting ribosomal release factors
The bacterial ribosome is an important drug target for antibiotics that can inhibit different stages of protein synthesis. Among the various classes of compounds that impair translation there are, however, no known small-molec... |
Interstitial pneumonia in a glassblower: think to chronic beryllium disease!
Chronic beryllium disease (CBD) is an occupational illness with varying severity. In this report, we describe a 27 year old man, glassblower, who developed a fatal CBD after six months of unknown Beryllium's exposure. The diagnosis was suspec... |
Psychosocial effects of social media on the Saudi society during the Coronavirus Disease 2019 pandemic: A cross-sectional study
The Coronavirus Disease 2019 (COVID-19) pandemic has been posing a substantial challenge to human survival and well-being, which rely on the actions and behaviors of individuals. It is essent... |
CD123 and More: How to Target the Cell Surface of Blastic Plasmacytoid Dendritic Cell Neoplasm
Citation: Bôle-Richard, E.; Pemmaraju, N.; Caël, B.; Daguindau, E.; Lane, A.A. CD123 and More: How
# Introduction
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive leukemia characterized by a clo... |
Perceptions of treatment for tics among young people with Tourette syndrome and their parents: a mixed methods study
Background: Tourette syndrome (TS) among young people is associated with psychosocial difficulties and parents play an important role in the management of the condition. Clinical guidelines have been de... |
Plasma GDF15 level is elevated in psychosis and inversely correlated with severity
Accumulating evidence suggests that GDF15 is a biomarker for ageing and morbidity of many somatic disorders such as cancer and inflammatory disorders. Recently, elevated serum GDF15 level was proposed as a marker for mood disorder. Howe... |
Molecular mechanisms of zika virus pathogenesis: An update
[bib_ref] Pathogenesis of flavivirus infections: Using and abusing the host cell, Fernandez-Garcia [/bib_ref] [fig_ref] Figure 1: Genetic organization of Zika virus [/fig_ref] [bib_ref] Flaviviruses: Braking the entering, Pierson [/bib_ref] [bib_ref] Flavivir... |
Recombinant expression of osmotin in barley improves stress resistance and food safety during adverse growing conditions
BackgroundAlthough many genetic manipulations of crops providing biofortified or safer food have been done, the acceptance of biotechnology crops still remains limited. We report on a transgenic bar... |
Differential oestrogen receptor binding is associated with clinical outcome in breast cancer
[formula] B%D%(1D)F) BFDCCFD%+F A' B 0EDB%)DC0B EBDE%FDC1F A' ) BEDEF0D%0C BFD(0+D+%( A' B )11D1CEDCEF E)D((+D1EB A' ) BEDE1(DC1) BFD01CD+B1 A' B B0D10+D0+) BFD%0BDE(B A' ) FBDBFFD0)C BCDC01DFF1 A' B FEDFFCD1+1 FBD)FCDFB) A' ... |
The Potential Use of Metabolic Cofactors in Treatment of NAFLD
Non-alcoholic fatty liver disease (NAFLD) is caused by the imbalance between lipid deposition and lipid removal from the liver, and its global prevalence continues to increase dramatically. NAFLD encompasses a spectrum of pathological conditions including ... |
Demographic, Clinical and Management Characteristics of Newly Diagnosed COPD Patients in Turkey: A Real-Life Study
Purpose: In order to determine the clinical and sociodemographic characteristics of newly diagnosed treatment-naïve asthma and COPD patients in Turkey, a multicenter study in 2012 was initiated . We aimed... |
Large-scale synthesis of graphene and other 2D materials towards industrialization
The effective application of graphene and other 2D materials is strongly dependent on the industrial-scale manufacturing of films and powders of appropriate morphology and quality. Here, we discuss three state-of-the-art mass production... |
LC-MSsim – a simulation software for liquid chromatography mass spectrometry data
Several of the tools that we tested depend a lot on suitable parameters. Nevertheless, most parameters are not well documented. On the other hand, some tools work "outof-the-box" and do not offer any parameters that could be adopted.
We ... |
Exercise Addiction and Its Relationship with Health Outcomes in Indoor Cycling Practitioners in Fitness Centers
We studied the prevalence and possible association between exercise addiction and health in indoor cycling practitioners. In 1014 (492 women) adult indoor cyclists and 926 (597 women) controls with low level... |
A Research Agenda for Malaria Eradication: Cross-Cutting Issues for Eradication
Discipline-specific Malaria Eradication ResearchAgenda (malERA) Consultative Groups have recognized several cross-cutting issues that must be addressed to prevent repetition of some of the mistakes of past malaria elimination campaigns in ... |
Spatial early warning signals of social and epidemiological tipping points in a coupled behaviour-disease network
the resurgence of infectious diseases due to vaccine refusal has highlighted the role of interactions between disease dynamics and the spread of vaccine opinion on social networks. Shifts between disease e... |
Biomarkers of collagen synthesis predict progression in the PROFILE idiopathic pulmonary fibrosis cohort
Idiopathic pulmonary fibrosis (IPF) is characterised by excessive extracellular matrix (ECM) deposition and remodelling. Measuring this activity provides an opportunity to develop tools capable of identifying indiv... |
Safety assessment of genetically modified plants with deliberately altered composition
# Introduction
The food and feed risk assessment strategy for genetically modified (GM) crops in Europe, as applied by the European Food Safety Authority (EFSA) GMO Panel, compares GM plants and their derived food and feed with a ... |
Obsessive-compulsive disorder in children and adolescents: epidemiology, diagnosis and management
Obsessive-compulsive disorder (OCD) can be found in about 4% of the general population and is characterized by various compulsions and obsessions that interfere with the person's quality of life from a mild to severe degr... |
The Th1:Th2 Dichotomy of Pregnancy and Preterm Labour
Pregnancy is a unique immunological state in which a balance of immune tolerance and suppression is needed to protect the fetus without compromising the mother. It has long been established that a bias from the T helper 1 cytokine profile towards the T helper 2 pro... |
Double mutation (R124H, N544S) of TGFBI in two sisters with combined expression of Avellino and lattice corneal dystrophies
Purpose:The R124H mutation of the keratoepithelin gene (TGFBI) causes Avellino corneal dystrophy whereas the N544S mutation of this same gene gives rise to lattice corneal dystrophy. We now repor... |
Circulating tumor DNA in hepatocellular carcinoma: trends and challenges
Molecular characterization of individual patients' tumor cells is becoming increasingly important in offering effective treatment for patients in clinical practice. Recent advances in the field have indicated that circulating tumor DNA (ctDNA) ha... |
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