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A novel long non-coding RNA AC073352.1 promotes metastasis and angiogenesis via interacting with YBX1 in breast cancer
Breast cancer is the major cause of cancer death worldwide in women. Patients with metastasis have poor prognosis and the mechanisms of breast cancer metastasis are not completely understood. Long non... |
Management Options for Extensor Mechanism Discontinuity in Patients With Total Knee Arthroplasty
# Introduction and background
The extensor mechanism of the knee joint is one of the most important structures encountered during total knee arthroplasty. It consists of the quadriceps tendon, patella, and patellar tendo... |
The Interplay between PolyQ and Protein Context Delays Aggregation by Forming a Reservoir of Protofibrils
Polyglutamine (polyQ) diseases are inherited neurodegenerative disorders caused by the expansion of CAG codon repeats, which code for polyQ in the corresponding gene products. These diseases are associated with th... |
Hypothalamic glioma masquerading as craniopharyngioma
Hypothalamic glioma account for 10-15% of supratentorial tumors in children. They usually present earlier (first 5 years of age) than craniopharyngioma. Hypothalamic glioma poses a diagnostic dilemma with craniopharyngioma and other hypothalamic region tumors, when... |
Prehabilitation with wearables versus standard of care before major abdominal cancer surgery: a randomised controlled pilot study (trial registration: NCT04047524)
Background Prehabilitation aims to improve post-operative outcomes by enhancing pre-operative fitness but is labourintensive. This pilot study aimed to ass... |
End-of-life discussions reduce the utilization of life-sustaining treatments during the last three months of life in cancer patients
Studies to examine the impact of end-of-life (EOL) discussions on the utilization of life-sustaining treatments near death are limited and have inconsistent findings. This nationwide pop... |
The Origin of Variation in Primary Care Process and Outcome Indicators
Healthcare providers are often evaluated by studying variability in their indicators. However, the usefulness of this analysis may be limited if we do not distinguish the variability attributable to health professionals and organizations from that ... |
Global hypomyelination of the brain white and gray matter in schizophrenia: quantitative imaging using macromolecular proton fraction
Myelin deficiency is commonly recognized as an important pathological feature of brain tissues in schizophrenia (SZ). In this pilot study, global myelin content abnormalities in white m... |
Patients’ and Caregivers’ Experiences with the Multi-Payer Advanced Primary Care Practice Demonstration
# Introduction
In recent years, Centers for Medicare & Medicaid Services (CMS) and other payers have invested significant resources in testing the patient-centered medical home (PCMH) model as a means to improve t... |
Clinical Application of Rapid Upper Limb Assessment and Nordic Musculoskeletal Questionnaire in Work-Related Musculoskeletal Disorders: A Bibliometric Study
Citation: Kakaraparthi, V.N.; Vishwanathan, K.; Gadhavi, B.; Reddy, R.S.; Tedla, J.S.; Alshahrani, M.S.; Dixit, S.; Gular, K.; Zaman, G.S.; Gannamaneni, V.K.; et ... |
Obstetrics and Gynecology
OBSTETRICS AND GYNECOLOGY
M.DM.DOBSTETRICS AND GYNECOLOGY
The Time to Operate in Tubal Pregnancy.During the past year a prolonged discussion lias been going 011 in the American journals as to which is the best time for operative interference in cases of tubal pregnancy, and more particularly ... |
Computational Modeling and Neuroimaging Techniques for Targeting during Deep Brain Stimulation
Accurate surgical localization of the varied targets for deep brain stimulation (DBS) is a process undergoing constant evolution, with increasingly sophisticated techniques to allow for highly precise targeting. However, des... |
Acute liver lobe torsion in a kitten
# Introduction
An acute abdomen is a common presentation seen at veterinary emergency hospitals caused by various etiologies. An acute abdomen secondary to a liver lobe torsion (LLT) is rarely reported in dogs, cats, horses and humans, but is relatively frequent in the rabbit. Th... |
NF‐κB inhibition reverses acidic bile‐induced miR‐21, miR‐155, miR‐192, miR‐34a, miR‐375 and miR‐451a deregulations in human hypopharyngeal cells
We previously demonstrated that acidic bile activates NF-jB, deregulating the expression of oncogenic miRNA markers, in pre-malignant murine laryngopharyngeal mucosa.Here, w... |
Renal Leiomyosarcoma, a Rare Presentation
Renal sarcomas are very rare malignant tumours with a very poor prognosis. Renal leiomyosarcoma, a malignant tumour of smooth muscle origin, is the most common histological type. The article reports a case of leiomyosarcoma of renal location, with a review of the literature. A... |
Clinical and research applications of a brain tumor tissue bank in the age of precision medicine
## A multidisciplinary team for successful tumor banking & precision medicine research
Much like the multidisciplinary teams that manage patient care, a multidisciplinary collaboration is necessary to generate and mainta... |
Salvage therapies in relapsed and/or refractory myeloma: what is current and what is the future?
The treatment landscape for multiple myeloma (MM) is evolving with our understanding of its pathophysiology. However, given the inevitable cohort heterogeneity in salvage therapy, response to treatment and overall prognose... |
Substance abuse among high school learners in a rural education district in the Free State province, South Africa
Background: In South Africa, many studies conducted on substance abuse among in-school youth focus on urban areas. However, anecdotal evidence suggests that rural areas are experiencing an increase in subs... |
Presence of Li Clusters in Molten LiCl-Li
## Supporting information
The Raman spectra of LiCl-Li 2 O-Li were recorded with varying incident laser power between 0 and 10mW to quantify the dependence of the signal on the power of the laser. 1 shows the spectra recorded at various laser powers, along with a plot of the... |
Transferable Coarse-Grained Potential for De Novo Protein Folding and Design
Protein folding and design are major biophysical problems, the solution of which would lead to important applications especially in medicine. Here we provide evidence of how a novel parametrization of the Caterpillar model may be used for bot... |
Effect of Front-of-Package Information, Fruit Imagery, and High–Added Sugar Warning Labels on Parent Beverage Choices for Children
IMPORTANCE Fruit drinks are widely consumed by young children, and many parents mistakenly believe that these drinks are healthy, potentially due to front-of-package claims and imagery.Res... |
Fractional laser therapy – the next step in alleviating the symptoms of skin aging (own observations)
Skin aging is a natural process of the skin, which accelerates in menopause and is additionally intensified by accumulating effects of repeated exposure to solar UV radiation and other external factors. Anti-aging ski... |
In vitroassembly of the bacterial actin protein MamK from ‘CandidatusMagnetobacterium casensis’ in the phylumNitrospirae
# Supplemental methods
Cloning, expression and purification. The mamK gene was amplified from Mcas genomic DNA using the primers WB643 (AAGGCATATGACAAAAACAAAGATACTTAACA) and WB567
(TTCAAGCTTTTATCG... |
Genome-scale target identification in Escherichia coli for high-titer production of free fatty acids
To construct a superior microbial cell factory for chemical synthesis, a major challenge is to fully exploit cellular potential by identifying and engineering beneficial gene targets in sophisticated metabolic networks... |
Opportunities for Refinement of Non-Human Primate Vaccine Studies
Citation: Prescott, M.J.; Clark, C.; Dowling, W.E.; Shurtleff, A.C. Opportunities for Refinement of Non-Human Primate Vaccine Studies. Vaccines 2021, 9, 284. https://
# Introduction
Animal models remain an integral part of the immunogenicity, efficacy,... |
Epstein-Barr Virus-Encoded RNAs: Key Molecules in Viral Pathogenesis
The Epstein-Barr virus (EBV) is known as an oncogenic herpesvirus that has been implicated in the pathogenesis of various malignancies. EBV-encoded RNAs (EBERs) are non-coding RNAs expressed abundantly in latently EBV-infected cells. Herein, I summar... |
Sequence Inversion to Facilitate Concurrent Radiotherapy and Systemic Therapy. A Proof of Principle Study in the Setting of a Phase II Randomized Trial in Prostate Cancer
Background: Concomitant chemo-radiation for pelvic cancers remains challenging to be delivered at full doses. We hypothesized that fewer delays in c... |
Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of Induced Fit on Enzyme Catalysis
For several decades, molecular recognition has been considered one of the most fundamental processes in biochemistry. For enzymes, substrate binding is often coupled to conformational chan... |
Controlling Spatial Distributions of Molecules in Multicomponent Organic Crystals, with Quantitative Mapping by Confocal Raman Microspectrometry
We report four experimental strategies for controlling the three-dimensional arrangement of molecules in multicomponent organic crystals, exploiting confocal Raman microspect... |
Stability and Feasibility of Dried Blood Spots for Hepatitis E Virus Serology in a Rural Setting
# Introduction
Hepatitis E virus (HEV) is a major cause of acute hepatitis around the world, but with a disproportionately high burden in low-income countries, where pregnant women and their offspring are at particular r... |
Exploring Cross-Sectoral Implications of the Sustainable Development Goals: Towards a Framework for Integrating Health Equity Perspectives With the Land-Water-Energy Nexus
Objectives: To assess existing evidence and identify gaps in the integrative framework of the Sustainable Development Goals (SDGs) for their potent... |
Illicit Tobacco in Lithuania: A Cross-Sectional Survey
Taxation policies are the most cost-effective measure to reduce overall tobacco consumption. However, cigarettes in Lithuania are among the cheapest in the European Union. The threat of the illicit trade is often used to compromise evidence-based policies, pricing... |
Occupational cancer in central European countries.
The countries of central Europe, including Poland, the Czech Republic, Slovakia, Hungary, Romania, and Bulgaria, suffer from environmental and occupational health problems created during the political system in place until the late 1980s. This situation is reflected b... |
Explaining Racial Inequality in Food Security in Columbus, Ohio: A Blinder–Oaxaca Decomposition Analysis
Food insecurity is a leading public health challenge in the United States. In Columbus, Ohio, as in many American cities, there exists a great disparity between Black and White households in relation to food insecu... |
Hemophagocytic Lymphohistiocytosis Complicated by Acute Respiratory Distress Syndrome and Multiorgan Failure
Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening condition that is characterized by an overactive response of the immune system with excessive production of proinflammatory cytokines. Ini... |
Unexpected pain with electrocortical stimulation in a teenager with temporal encephalocele
a b s t r a c tTemporal lobe encephalocele has emerged as a potentially unrecognized cause of drug-resistant temporal lobe epilepsy (TLE) that can be effectively treated with epilepsy surgery. Here we present a case in which a 1... |
Unique Transcriptome Patterns of the White and Grey Matter Corroborate Structural and Functional Heterogeneity in the Human Frontal Lobe
The human frontal lobe has undergone accelerated evolution, leading to the development of unique human features such as language and self-reflection. Cortical grey matter and underly... |
Proteomic Approaches to Defining Remission and the Risk of Relapse in Rheumatoid Arthritis
Objectives: Patients with Rheumatoid Arthritis (RA) are increasingly achieving stable disease remission, yet the mechanisms that govern ongoing clinical disease and subsequent risk of future flare are not well understood. We sou... |
Protocol for the economic evaluation of the InTENSE program for rehabilitation of chronic upper limb spasticity
Background: Assessment of the costs of care associated with chronic upper-limb spasticity following stroke in Australia and the potential benefits of adding intensive upper limb rehabilitation to botulinum t... |
A qualitative examination of the usability of a digital cognitive behavioral therapy for insomnia program after stroke
Objective: Sleep is commonly impaired after stroke. Cognitive Behavioral Therapy for Insomnia (CBT-I) is the first-line recommended treatment for sleep difficulty. "Sleepio" is a digital CBT-I program... |
Applications of Deep Learning for Dense Scenes Analysis in Agriculture: A Review
Deep Learning (DL) is the state-of-the-art machine learning technology, which shows superior performance in computer vision, bioinformatics, natural language processing, and other areas. Especially as a modern image processing technology,... |
Non-disclosure of tuberculosis diagnosis by patients to their household members in south western Uganda
BackgroundTuberculosis (TB) non-disclosure by adult patients to all household members is a setback to TB control efforts. It reduces the likelihood that household contacts will seek early TB screening, initiation on... |
An Introduction to Bacterial Biofilms and Their Proteases, and Their Roles in Host Infection and Immune Evasion
## The complexity of bacterial biofilms
Bacteria are single-celled microorganisms that are commonly associated with being independent, free-living organisms. However, they frequently adhere to surfaces to ... |
HER2-Altered Non-Small Cell Lung Cancer: Biology, Clinicopathologic Features, and Emerging Therapies
Multiple oncogenic molecular alterations have been discovered that serve as potential drug targets in non-small cell lung cancer (NSCLC). While the pathogenic and pharmacological features of common targets in NSCLC hav... |
Effects of prenatal nutrient supplementation and early life exposures on neurodevelopment at age 10: a randomised controlled trial - the COPSYCH study protocol
# Introduction
Mounting evidence suggests that health and disease are programmed in early life, and that a wide range of prenatal and early life exposures af... |
Individual and partnership characteristics associated with consistent condom use in a cohort of cisgender men who have sex with men and transgender women in Nigeria
Background: This study reports on the individual and partnership characteristics that influence consistent condom use in cisgender men who have sex with m... |
Optical excitation and external photoluminescence quantum efficiency of Eu3+ in GaN
We investigate photoluminescence of Eu-related emission in a GaN host consisting of thin layers grown by organometallic vapor-phase epitaxy. By comparing it with a reference sample of Eu-doped Y 2 O 3 , we find that the fraction of Eu ... |
SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis
Background:Since the completion of the HapMap project, huge numbers of individual genotypes have been generated from many kinds of laboratories. The efforts of finding or interpreting genetic association betw... |
Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin‐Converting Enzyme Inhibitors and Angiotensin Receptor Blockers
Background--Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to e... |
Background: Spinal epidural hematoma is a rare condition usually secondary to trauma and coagulopathy. To the best of our knowledge, we present the first case of a patient with an iatrogenic hypercoaguable state performing self-neck manipulation, which resulted in a spinal epidural hematoma and subsequent quadriparesis... |
Nothing in Evolution Makes Sense Except in the Light of Genomics: Read–Write Genome Evolution as an Active Biological Process
The 21st century genomics-based analysis of evolutionary variation reveals a number of novel features impossible to predict when Dobzhansky and other evolutionary biologists formulated the neo-... |
Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) Equation Pronouncedly Underestimates Glomerular Filtration Rate in Type 2 Diabetes
OBJECTIVEdTo evaluate the performance of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation to estimate glomerular filtration rate (GFR) in type 2 diabeti... |
Computer assisted diagnosis of Alzheimer’s disease using statistical likelihood-ratio test
The purpose of this work is to present a computer assisted diagnostic tool for radiologists in their diagnosis of Alzheimer's disease. A statistical likelihood-ratio procedure from signal detection theory was implemented in the ... |
Cytotoxicity of 15-Deoxy-Δ12,14-prostaglandin J2 through PPARγ-independent Pathway and the Involvement of the JNK and Akt Pathway in Renal Cell Carcinoma
Introduction:Agonists of peroxisome proliferator-activated receptor gamma (PPARγ) have been examined as chemopreventive and chemotherapeutic agents. The aim was to i... |
An Updated Overview on Therapeutic Drug Monitoring of Recent Antiepileptic Drugs
Given the distinctive characteristics of both epilepsy and antiepileptic drugs (AEDs), therapeutic drug monitoring (TDM) can make a significant contribution to the field of epilepsy. The measurement and interpretation of serum drug concen... |
A selective cyclic integrin antagonist blocks the integrin receptors αvβ3 and αvβ5 and inhibits retinal pigment epithelium cell attachment, migration and invasion
Background: Proliferative vitreoretinopathy (PVR) is a leading cause of blindness after failed retinal reattachment surgery. PVR is characterized by the pro... |
Attitudes towards Violence in Adolescents and Youth Intimate Partner Relationships: Validation of the Spanish Version of the EAV
# Introduction
An increasing interest is being devoted to intimate partner violence (IPV), due to the severe physical, psychological, and social consequences associated, as well as the gro... |
Somatic Mutation Profiles of MSI and MSS Colorectal Cancer Identified by Whole Exome Next Generation Sequencing and Bioinformatics Analysis
Background: Colorectal cancer (CRC) is with approximately 1 million cases the third most common cancer worldwide. Extensive research is ongoing to decipher the underlying genetic ... |
Eosinophilic Esophagitis in Children: Clinical Findings and Diagnostic Approach
Eosinophilic esophagitis (EoE) is an emerging chronic immune and antigen-mediated clinicopathologic disease. During the last 2 decades, the incidence of this condition in children has increased significantly, thanks to practitioners for cr... |
The Role of Isoflavones in the Prevention of Breast Cancer and Prostate Cancer
Citation: Pejčić, T.; Zeković, M.; Bumbaširević, U.; Kalaba, M.; Vovk, I.; Bensa, M.; Popović, L.; Tešić, Ž. (I.V.) † These authors contributed equally to this work.Abstract: This narrative review summarizes epidemiological studies on breas... |
Seeing Mixed Emotions: The Specificity of Emotion Perception From Static and Dynamic Facial Expressions Across Cultures
Although perceivers often agree about the primary emotion that is conveyed by a particular expression, observers may concurrently perceive several additional emotions from a given facial expression. ... |
Morgellons disease: a filamentous borrelial dermatitis
Morgellons disease (MD) is a dermopathy characterized by multicolored filaments that lie under, are embedded in, or project from skin. Although MD was initially considered to be a delusional disorder, recent studies have demonstrated that the dermopathy is associa... |
Surgical Versus Non-Surgical Treatment for Vertebral Compression Fracture with Osteopenia: A Systematic Review and Meta-Analysis
BackgroundSurgical and non-surgical interventions are the two categories for treatment of vertebral compression fractures (VCFs). However, there is clinical uncertainty over optimal manageme... |
Formation in Interprofessional Education in Nursing and Medical Students Globally. Scoping review
Objective. This work sought to know the state of the art related to the theme of Interprofessional Education (IPE) in the training of Nursing and Medical students and the level of evidence developed thus far. Methods. and... |
Modifications to residential neighbourhood characteristics and risk of 79 common health conditions: a prospective cohort study
## Description of study population
Men and women participating in HeSSup were from a stratified random sample of the Finnish population based on four age groups (20-24, 30-34, 40-44, and 50-... |
Early ultrasound diagnosis of conjoined twins at eight weeks of pregnancy: A case report
BACKGROUNDConjoined twins are a rare occurrence, and the majority of these malformations are detected during second trimester screening.CASE SUMMARYHerein we report a case of conjoined twins, which was diagnosed by ultrasound at 8... |
Dr. Edward Jenner on the Influence of Artificial Eruptions in Various Diseases
## 1822]
JDtr. Jenner on Artificial Eruptions. 91 symptoms of which are too well known. In addition to the usual phenomena, however, " there was a perceptible enlargement about the centre of the left side of the thorax." To engage his min... |
Functional connectivity of the human amygdala in health and in depression
To analyse the functioning of the amygdala in depression, we performed the first voxel-level resting state functionalconnectivity neuroimaging analysis of depression of voxels in the amygdala with all other voxels in the brain, with 336 patients... |
Access to the NHS by telephone and Internet during an influenza pandemic: an observational study
Objectives: To examine use of a novel telephone and Internet service-the National Pandemic Flu Service (NPFS)-by the population of England during the 2009-2010 influenza pandemic. Setting: National telephone and Internet-b... |
Responding to the deaf in disasters: establishing the need for systematic training for state-level emergency management agencies and community organizations
Background: Deaf and hard-of-hearing (Deaf/HH) individuals have been underserved before and during emergencies. This paper will assess Deaf/HH related emergency p... |
COVID-19 and the intensive care unit: vaccines to the rescue
# Declarations
## Conflicts of interest
The authors declare that they no conflict of interest.
## Open access
This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sh... |
New method for detection of complex 3D fracture motion - Verification of an optical motion analysis system for biomechanical studies
Background: Fracture-healing depends on interfragmentary motion. For improved osteosynthesis and fracturehealing, the micromotion between fracture fragments is undergoing intensive resea... |
Getting under the skin of the primary care consultation using video stimulated recall: a systematic review
Background: Video stimulated recall (VSR) is a method of enhancing participants' accounts of the consultation using a video recording of the event to encourage and prompt recall in a post consultation interview. ... |
Clinician views on best practice community care for people with complex emotional needs and how it can be achieved: a qualitative study
Background: Individuals with Complex Emotional Needs (CEN) services, a working description to refer to the needs experienced by people who may have been diagnosed with a "personality ... |
Predicting the Perceived Sound Quality of Frequency-Compressed Speech
The performance of objective speech and audio quality measures for the prediction of the perceived quality of frequencycompressed speech in hearing aids is investigated in this paper. A number of existing quality measures have been applied to speech... |
Quantifying the role of steric constraints in nucleosome positioning
Statistical positioning describes how the combination of (1) barriers confining nucleosome movement and (2) inter-nucleosomal steric hindrance affects the distribution of densely packed nucleosomes. In this framework, the nucleosomes are modeled as o... |
SEPPA 3.0—enhanced spatial epitope prediction enabling glycoprotein antigens
B-cell epitope information is critical to immune therapy and vaccine design. Protein epitopes can be significantly affected by glycosylation, while no methods have considered this till now. Based on previous versions of Spatial Epitope Predic... |
An unusual unifocal presentation of Castleman’s disease in a young woman with a detailed description of sonographic findings to reduce diagnostic uncertainty: a case report
Background: Castleman's disease is a rare lymphoproliferative disorder. It typically presents as mediastinal masses and causes a wide range of cli... |
Efficient and secure three-party mutual authentication key agreement protocol for WSNs in IoT environments
In the Internet of Things (IoT), numerous devices can interact with each other over the Internet. A wide range of IoT applications have already been deployed, such as transportation systems, healthcare systems, s... |
Oculomotor inhibition precedes temporally expected auditory targets
## Reviewer #1:
Consistent with previous work, the authors demonstrate that saccade execution is modulated by the predictability of a target. In a novel expansion of prior studies, this manuscript presents a case in which these relationships exist ... |
Vaginal Bleeding in an Infant with Extreme Prematurity
Background. Minipuberty of infancy refers to the transient activation of the hypothalamic-pituitary-gonadal (HPG) axis during the first few months of life. Studies have documented a more exaggerated and prolonged gonadotropin surge in preterm infants compared with... |
The Role of Alternative Crops in an Upcoming Global Food Crisis: A Concise Review
[bib_ref] Preventing food crises using a food policy approach, Timmer [/bib_ref] [bib_ref] The food crisis isn't over, Braun [/bib_ref] [bib_ref] Effect of COVID-19 on agricultural production and food security: A scientometric analysis,... |
Obesity may increase survival, regardless of nutritional status: a Swedish cohort study in nursing homes
Background: To investigate the associations between the body mass index (BMI), Mini Nutritional Assessment-Short Form (MNA-SF) scores, and 2-year mortality.Methods: A nationwide cohort study using data from a natio... |
Phylogenetic analysis and development of molecular markers for five medicinal Alpinia species based on complete plastome sequences
Background: Alpinia species are widely used as medicinal herbs. To understand the taxonomic classification and plastome evolution of the medicinal Alpinia species and correctly identify me... |
Sediment Facilitates Microbial Degradation of the Herbicides Endothall Monoamine Salt and Endothall Dipotassium Salt in an Aquatic Environment
Endothall dipotassium salt and monoamine salt are herbicide formulations used for controlling submerged aquatic macrophytes and algae in aquatic ecosystems. Microbial activity ... |
Effects of Glenoid and Humeral Bone Defects on Recurrent Anterior Instability of the Shoulder
## Effect of glenoid bone defects
Glenoid bone defects are known as one of the important risk factors for recurrence after surgical treatment of instability.The size of a glenoid bone defect should be preoperatively estimat... |
Noli Timere: The Role of Reassuring Adults in Dealing with COVID-19 Anxiety in Pediatric Age
# Introduction
In a recent study [bib_ref] Anxiety in Older Adolescents at the Time of COVID-19, Smirni [/bib_ref] unexpected high level of 'state-anxiety' was recorded in a group of Italian healthy older adolescents during ... |
Outbreak of Invasive Wound Mucormycosis in a Burn Unit Due to Multiple Strains of Mucor circinelloides f. circinelloides Resolved by Whole-Genome Sequencing
Mucorales are ubiquitous environmental molds responsible for mucormycosis in diabetic, immunocompromised, and severely burned patients. Small outbreaks of invasiv... |
Oxidative Stress in Age-Related Neurodegenerative Diseases: An Overview of Recent Tools and Findings
Reactive oxygen species (ROS) have been described to induce a broad range of redoxdependent signaling reactions in physiological conditions. Nevertheless, an excessive accumulation of ROS leads to oxidative stress, whi... |
# Introduction
Myocardial bridge (MB) is defined as an epicardial segment of the coronary artery which takes an intramyocardial course, resulting in systolic compression. [bib_ref] Myocardial bridging: a review with emphasis on electrocardiographic findings, Rovai [/bib_ref] It was first recognized at autopsy by Reym... |
Establishing the characteristics of an effective pharmacogenetic test for clozapine-induced agranulocytosis
# Introduction
Although there are 22 FDA-approved antipsychotics used to treat schizophrenia, around 30% of schizophrenia patients do not respond to drugs other than clozapine. [bib_ref] Treatment-resistant sc... |
Cross-neutralization of SARS-CoV-2 B.1.1.7 and P.1 variants in vaccinated, convalescent and P.1 infected
# Introduction
More than one year after the declaration of Coronavirus disease 2019 (COVID-19) as a pandemic, 1 severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is still spreading around the world cau... |
The potential role of peak nasal inspiratory flow to evaluate active sinonasal inflammation and disease severity
Although the pathophysiology of nasal polyposis is incompletely understood, rhinologists have seldom studied it with rhinomanometry or peak nasal inspiratory flow (PNIF) due to technical limitations and the... |
Atypical presentation of complex regional pain syndrome: neuropathic itching - A case report -
KSPSComplex regional pain syndrome (CRPS) is a painful disorder, characterized by pain following an inciting injury and a variable convergence of signs and symptoms of sensory, vasomotor, sudomotor, trophic, and motor dysfun... |
Emergency Management of Medical Wastewater in Hospitals Specializing in Infectious Diseases: A Case Study of Huoshenshan Hospital, Wuhan, China
# Introduction
The novel coronavirus disease (COVID-19) first appeared in Wuhan, China, in December 2020, before spreading rapidly worldwide [bib_ref] SARS-CoV-2 in hospital... |
Chinese Consensus Report on Family-Based Helicobacter pylori Infection Control and Management (2021 Edition)
# Introduction
Helicobacter pylori has infected half of the world population and is a major health threat for Chinese families and society. It is also a heavy economic and healthcare burden for the country du... |
Does Facial Resemblance Enhance Cooperation?
Facial self-resemblance has been proposed to serve as a kinship cue that facilitates cooperation between kin. In the present study, facial resemblance was manipulated by morphing stimulus faces with the participants' own faces or control faces (resulting in self-resemblant ... |
Protocol: Adaptive Implementation of Effective Programs Trial (ADEPT): cluster randomized SMART trial comparing a standard versus enhanced implementation strategy to improve outcomes of a mood disorders program
Background: Despite the availability of psychosocial evidence-based practices (EBPs), treatment and outcomes... |
Totally Tubeless Outpatient Percutaneous Nephrolithotomy: Initial Case Report
We report the first case of totally tubeless outpatient percutaneous nephrolithotomy (PCNL). Our patient was discharged home safely less than 4 hours following uncomplicated PCNL with no nephrostomy tube, ureteral stent, or urethral catheter... |
Evaluation of Children Caries Risk Factors: A Narrative Review of Nutritional Aspects, Oral Hygiene Habits, and Bacterial Alterations
Citation: Butera, A.; Maiorani, C.; Morandini, A.; Simonini, M.; Morittu, S.; Trombini, J.; Scribante, A.
# Introduction
Dental caries is one of the most common chronic conditions in c... |
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