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Answer the following medical question with one of the provided options: | Q:A 10-year-old girl with a rash is brought to the clinic by her mother. The patient’s mother says that the onset of the rash occurred 2 days ago. The rash was itchy, red, and initially localized to the cheeks with circumoral pallor, and it gradually spread to the arms and trunk. The patient’s mother also says her daug... | C: Discharge home, saying that the patient may immediately return to school |
Answer the following medical question with one of the provided options: | Q:A 54-year-old male presents to the emergency department after an episode of bloody vomiting. He is a chronic alcoholic with a history of cirrhosis, and this is the third time he is presenting with this complaint. His first two episodes of hematemesis required endoscopic management of bleeding esophageal varices. His ... | B: Discuss with the patient the option of a transjugular intrahepatic portosystemic stent (TIPS) |
Answer the following medical question with one of the provided options: | Q:A 45-year-old man is brought into the emergency department after he was hit by a car. The patient was intoxicated and walked into oncoming traffic. He is currently unconscious and has a Glasgow coma scale score of 3. The patient has been admitted multiple times for alcohol intoxication and pancreatitis. The patient i... | D: Transfusion complication |
Answer the following medical question with one of the provided options: | Q:A 57-year-old woman is admitted to the intensive care unit for management of shock. Her pulse is feeble and blood pressure is 86/45 mm Hg. The patient undergoes pulmonary artery catheterization which shows an elevated pulmonary capillary wedge pressure and increased systemic vascular resistance. Which of the followin... | E: Confusion due to decreased stroke volume |
Answer the following medical question with one of the provided options: | Q:A 65-year-old Caucasian man presents to the emergency room with chest pain. Coronary angiography reveals significant stenosis of the left anterior descending (LAD) artery. Which of the following represents a plausible clinical predictor of myocardial necrosis in this patient?? {'A': 'Cholesterol crystal presence', 'B... | B: Rate of plaque formation |
Answer the following medical question with one of the provided options: | Q:A 30-year-old woman comes to the physician because of a 1-month history of intermittent abdominal pain, flatulence, and watery diarrhea. The episodes typically occur 2–3 hours after meals, particularly following ingestion of ice cream, cheese, and pizza. She is administered 50 g of lactose orally. Which of the follow... | C: Increased stool osmotic gap |
Answer the following medical question with one of the provided options: | Q:A 70-year-old male with a 10-year history of COPD visits his pulmonologist for a checkup. Physical examination reveals cyanosis, digital clubbing, and bilateral lung wheezes are heard upon auscultation. The patient has a cough productive of thick yellow sputum. Which of the following findings is most likely present i... | B: Increased pulmonary arterial resistance |
Answer the following medical question with one of the provided options: | Q:Background and Methods: Aldosterone is important in the pathophysiology of heart failure. In a double-blind study, we enrolled 1,663 patients who had severe heart failure, a left ventricular ejection fraction of no more than 35 percent, and were being treated with an angiotensin-converting-enzyme inhibitor, a loop di... | A: Spironolactone, in addition to standard therapy, substantially reduces the risk of morbidity and death in patients with severe heart failure |
Answer the following medical question with one of the provided options: | Q:During an experiment, an investigator attempts to determine the rates of apoptosis in various tissue samples. Injecting cytotoxic T cells into the cell culture of one of the samples causes the tissue cells to undergo apoptosis. Apoptosis is most likely due to secretion of which of the following substances in this cas... | D: Granzyme B |
Answer the following medical question with one of the provided options: | Q:Which of the following situations calls for treatment with alprazolam?? {'A': 'A 28-year-old female that gets irritated or worried about everyday things out of proportion to the actual source of worry', 'B': 'A 35-year-old male that gets tachycardic, tachypnic, and diaphoretic every time he rides a plane', 'C': 'A 42... | B: A 35-year-old male that gets tachycardic, tachypnic, and diaphoretic every time he rides a plane |
Answer the following medical question with one of the provided options: | Q:A 30-year-old woman is brought to the clinic at her husband's insistence for sleep disturbances. Most nights of the week she repeatedly gets out of bed to pace around their apartment before returning to bed. The woman says that while she's lying in bed, she becomes overwhelmed by a "creepy-crawly" feeling in her legs... | A: Complete blood count |
Answer the following medical question with one of the provided options: | Q:A 40-year-old woman presents with ongoing heartburn despite being on treatment for the last few months. She describes a burning sensation in her chest even after small meals. She has stopped eating fatty and spicy foods as they aggravate her heartburn significantly. She has also stopped drinking alcohol but is unable... | C: Start metoclopramide. |
Answer the following medical question with one of the provided options: | Q:A 17-year-old girl presents to the emergency department with a severe headache. The patient has had headaches in the past, but she describes this as the worst headache of her life. Her symptoms started yesterday and have been getting progressively worse. The patient states that the pain is mostly on one side of her h... | E: Fat-soluble vitamin overuse |
Answer the following medical question with one of the provided options: | Q:A previously healthy 1-year-old boy is brought to the emergency department because of irritability and fever for 2 days. His symptoms began shortly after returning from a family trip to Canada. He was born at term. His immunizations are up-to-date. His 6-year-old brother is healthy and there is no family history of s... | D: Ceftriaxone and vancomycin therapy for the patient and rifampin prophylaxis for close contacts |
Answer the following medical question with one of the provided options: | Q:A 62-year-old woman is brought to the emergency room at a nearby hospital after being involved in a roadside accident in which she sustained severe chest trauma. Enroute to the hospital, morphine is administered for pain control. Upon arrival, the patient rapidly develops respiratory failure and requires intubation a... | C: Histamine release |
Answer the following medical question with one of the provided options: | Q:An investigator is studying intracellular processes in muscle tissue after denervation. A biopsy specimen is obtained from the biceps femoris muscle of an 82-year-old woman who sustained sciatic nerve injury. Investigation of the tissue specimen shows shrunken cells with dense eosinophilic cytoplasm, nuclear shrinkag... | A: Release of mitochondrial cytochrome c |
Answer the following medical question with one of the provided options: | Q:A 15-year-old girl is brought to the physician by her mother because of lower abdominal pain for the past 5 days. The pain is constant and she describes it as 7 out of 10 in intensity. Over the past 7 months, she has had multiple similar episodes of abdominal pain, each lasting for 4–5 days. She has not yet attained ... | D: Perform hymenotomy |
Answer the following medical question with one of the provided options: | Q:A 46-year-old woman comes to the physician for a cognitive evaluation. She is an office manager. She has had increasing difficulties with multitasking and reports that her job performance has declined over the past 1 year. On mental status examination, short-term memory is impaired and long-term memory is intact. Lab... | C: Mutation in presenilin 1 |
Answer the following medical question with one of the provided options: | Q:An investigator, studying learning in primates, gives an experimental chimpanzee a series of puzzles to solve. The chimpanzee solves the puzzle when he is able to place a set of wooden blocks sequentially inside the next biggest block. When a puzzle is solved successfully, a 30-second audio clip of a pop song plays. ... | D: Classical conditioning |
Answer the following medical question with one of the provided options: | Q:A 15-year-old male adolescent presents to the pediatrician with his parents complaining that he is shorter than his peers. His past medical history does not suggest any specific recurrent or chronic disease. There is no history of weight gain, weight loss, constipation, dry skin, headache. Both his parents are of nor... | A: Constitutional growth delay |
Answer the following medical question with one of the provided options: | Q:A 53-year-old female visits her physician with watery diarrhea and episodic flushing. The patient reports that she is often short of breath, and a pulmonary exam reveals bilateral wheezing. A CT scan shows a mass in the terminal ileum. 24-hour urine collection shows abnormally elevated 5-hydroxyindoleacetic acid (HIA... | D: Liver |
Answer the following medical question with one of the provided options: | Q:A patient weighing 70 kg (154 lb) requires intravenous antibiotics for a calcified abscess. The desired target plasma concentration of the antibiotic is 4.5 mg/L. The patient is estimated to have a volume of distribution of 30 L and a clearance rate of 60 mL/min. How many milligrams of the drug should be administered... | A: 135 mg |
Answer the following medical question with one of the provided options: | Q:An 82-year-old man with alcohol use disorder is brought to the emergency department from his assisted living facility because of fever and cough for 1 week. The cough is productive of thick, mucoid, blood-tinged sputum. His temperature is 38.5°C (101.3°F) and respirations are 20/min. Physical examination shows coarse... | D: Isolate patient to a single-occupancy room |
Answer the following medical question with one of the provided options: | Q:A 4-year-old boy presents to the Emergency Department with wheezing and shortness of breath after playing with the new family pet. Which of the following immunological factors is most involved in generating the antibodies necessary for mast cell Fc-receptor cross-linking and degranulation?? {'A': 'IL-2', 'B': 'IL-4',... | B: IL-4 |
Answer the following medical question with one of the provided options: | Q:A 35-year-old man is brought to his psychiatrist by his wife. The patient’s wife says his last visit was 3 years ago for an episode of depression. At that time, he was prescribed fluoxetine, which he did not take because he believed that his symptoms would subside on their own. A few months later, his wife says that ... | C: Cyclothymia |
Answer the following medical question with one of the provided options: | Q:A previously healthy 56-year-old woman comes to the family physician for a 1-month history of sleep disturbance and sadness. The symptoms have been occurring since her husband died in a car accident. Before eventually falling asleep, she stays awake for multiple hours and has crying spells. Several times she has been... | B: Normal bereavement |
Answer the following medical question with one of the provided options: | Q:A 75-year-old man comes to the physician because of a 2-month history of intermittent bright red blood in his stool, progressive fatigue, and a 5-kg (11-lb) weight loss. He appears thin and fatigued. Physical examination shows conjunctival pallor. Hemoglobin concentration is 7.5 g/dL and MCV is 77 μm3. Results of fec... | B: Internal iliac |
Answer the following medical question with one of the provided options: | Q:A 33-year-old woman presents with weight gain and marks on her abdomen (as seen in the image below). She does not have any significant past medical history. She is a nonsmoker and denies any alcohol use. Her blood pressure is 160/110 mm Hg and pulse is 77/min. A T1/T2 MRI of the head shows evidence of a pituitary ade... | C: Hydrocortisone |
Answer the following medical question with one of the provided options: | Q:A 58-year-old man presents with a sudden-onset severe headache and vomiting for the past 2 hours. Past medical history is significant for poorly controlled hypertension, managed with multiple medications. His blood pressure is 188/87 mm Hg and pulse is 110/min. A non-contrast CT of the head is unremarkable and cerebr... | D: Nimodipine |
Answer the following medical question with one of the provided options: | Q:A 25-year-old patient comes to the physician with complaints of dysuria and white urethral discharge. He is sexually active with 4 partners and does not use condoms. The physician is concerned for a sexually transmitted infection and decides to analyze the nucleic acid sequences present in the discharge to aid in dia... | E: Heat-resistant DNA polymerase |
Answer the following medical question with one of the provided options: | Q:A 61-year-old man is brought to the emergency department by his wife because of increasing confusion over the past 12 hours. His wife reports that he has a history of type 1 diabetes mellitus. His temperature is 38.8°C (101.8°F). He is confused and oriented only to person. Examination shows left periorbital swelling ... | B: Rhizopus microsporus |
Answer the following medical question with one of the provided options: | Q:A 57-year-old woman comes to the physician because of a 6-month history of tinnitus and progressive hearing loss in the left ear. She has type 2 diabetes mellitus and Raynaud syndrome. Her current medications include metformin, nifedipine, and a multivitamin. She appears well. Vital signs are within normal limits. Ph... | C: Acoustic neuroma |
Answer the following medical question with one of the provided options: | Q:A 4-week-old boy is brought to the emergency department with a 2-day history of projectile vomiting after feeding. His parents state that he is their firstborn child and that he was born healthy. He developed normally for several weeks but started to eat less 1 week ago. Physical exam reveals a small, round mass in t... | C: Nitric oxide synthase deficiency |
Answer the following medical question with one of the provided options: | Q:A 49-year-old woman is brought in to the emergency department by ambulance after developing crushing chest pain and palpitations. Past medical history is significant for hypertension, hyperlipidemia, and obesity. She takes chlorthalidone, lisinopril, atorvastatin, metformin, and an oral contraceptive every day. She w... | A: Inferior wall myocardial infarction |
Answer the following medical question with one of the provided options: | Q:A 60-year-old woman presents for an evaluation for snoring. According to her husband, her snoring has increased over the last year, and he can’t tolerate it anymore. He has also noticed that she wakes up at night regularly for a few seconds but then falls back asleep. During the day, the patient says she is sleepy mo... | A: Genioglossus muscle |
Answer the following medical question with one of the provided options: | Q:A 4-week-old male infant is brought to the physician because of a 1-week history of refusing to finish all his bottle feeds and becoming irritable shortly after feeding. He has also spit up sour-smelling milk after most feeds. Pregnancy and delivery were uncomplicated, with the exception of a positive vaginal swab fo... | B: Breastfeeding only |
Answer the following medical question with one of the provided options: | Q:A 52-year-old woman status-post liver transplant presents to her transplant surgeon because she has noticed increased urination over the last 3 weeks. Six months ago she received a liver transplant because of fulminant liver failure after viral hepatitis. Since then, she has noticed that she has been drinking more wa... | B: Binding to FKBP-12 to inhibit calcineurin |
Answer the following medical question with one of the provided options: | Q:A 47-year-old woman with a history of recent gastric bypass surgery presents for a follow-up visit. 8 months ago, she underwent gastric bypass surgery because she was struggling with maintaining her BMI below 42 kg/m². She previously weighed 120 kg (265 lb), and now she weighs 74.8 kg (165 lb). She says that she has ... | E: Iron |
Answer the following medical question with one of the provided options: | Q:A 19-year-old woman comes to the physician for a routine health maintenance examination. She appears well. Her vital signs are within normal limits. Cardiac auscultation shows a mid-systolic click and a grade 3/6, late-systolic, crescendo murmur that is best heard at the cardiac apex in the left lateral recumbent pos... | B: Dermatan sulfate deposition |
Answer the following medical question with one of the provided options: | Q:A 60-year-old woman with ovarian cancer comes to the physician with a 5-day history of fever, chills, and dyspnea. She has a right subclavian chemoport in which she last received chemotherapy 2 weeks ago. Her temperature is 39.5°C (103.1°F), blood pressure is 110/80 mm Hg, and pulse is 115/min. Cardiopulmonary examin... | C: Gram-positive, catalase-positive, coagulase-positive cocci in clusters |
Answer the following medical question with one of the provided options: | Q:A 28-year-old woman at 28 weeks gestation seeks evaluation at her obstetrician’s office with complaints of a severe headache, blurred vision, and vomiting for the past 2 days. Her pregnancy has been otherwise uneventful. The past medical history is unremarkable. The blood pressure is 195/150 mm Hg and the pulse is 88... | E: Nifedipine |
Answer the following medical question with one of the provided options: | Q:A 35-year-old G0P0000 presents to her gynecologist with complaints of irregular menstruation. She has had only two periods in the last year. She also endorses feeling flushed without provocation and experiencing occasional dyspareunia with post-coital spotting. In addition, she has also had more frequent headaches th... | C: Estradiol patch with oral medroxyprogesterone |
Answer the following medical question with one of the provided options: | Q:A 45-year-old man comes to the clinic complaining of yellow skin and eyes, loss of appetite, and severe nausea over the last month or so. He drinks 2–3 beers everyday and about 5–6 on the weekend. He does not take any over-the-counter medications. He has smoked one pack of cigarettes every day for the last 20 years b... | C: Alanine aminotransferase (ALT): 120 / Aspartate aminotransferase (AST): 256 / AST/ALT: 2.1 |
Answer the following medical question with one of the provided options: | Q:A 24-year-old man comes to the physician because of 2 episodes of bleeding from the rectum over the past month. The patient’s father died of colon cancer at the age of 42. The patient has no history of any serious illness and takes no medications. He does not smoke. His vital signs are within normal limits. Physical ... | B: Gardner’s syndrome |
Answer the following medical question with one of the provided options: | Q:A 56-year-old man is brought to the emergency department after falling 16 feet from a ladder. He has severe pain in both his legs and his right arm. He appears pale and diaphoretic. His temperature is 37.5°C (99.5°F), pulse is 120/min and weak, respirations are 26/min, and blood pressure is 80/50 mm Hg. He opens his ... | B: Urine output of 25 mL in 3 hours |
Answer the following medical question with one of the provided options: | Q:A 2-year-old boy is brought to the pediatrician for recurrent nosebleeds. The boy was adopted two months ago and the parents have no record of his medical or family history. They report that the child has had frequent prolonged nosebleeds several times per week. Despite them applying pressure on the distal aspect of ... | B: Autosomal recessive |
Answer the following medical question with one of the provided options: | Q:A 72-year-old man comes to the physician with his son for a follow-up examination. The son reports that his father's mental status has declined since the previous visit when he was diagnosed with Alzheimer dementia. The patient often begins tasks and forgets what he was doing. He has increased trouble remembering eve... | D: Memantine |
Answer the following medical question with one of the provided options: | Q:A 35-year-old female presents to her gynecologist complaining of vaginal discomfort. She reports that over the past two weeks, she has developed dyspareunia and feels as if there is a mass on the external aspect of her vagina. She is sexually active in a monogamous relationship. On physical examination, there is a 2 ... | C: Urogenital sinus |
Answer the following medical question with one of the provided options: | Q:A 34-year-old woman comes to the emergency department complaining of severe headache and anxiety, diaphoresis, and palpitations for the last 30 minutes. She has had several similar episodes over the past few weeks. She has no significant past medical history and has a 10 pack-year smoking history. She takes no illici... | D: Hypertension due to alpha-1-adrenergic receptor stimulation |
Answer the following medical question with one of the provided options: | Q:A 43-year-old woman comes to the physician with a 2-week history of new pruritic plaques on the scalp and extensor surfaces of the elbows and knees. Ten years ago, she was diagnosed with psoriasis. Her only medication is topical calcipotriene. Physical examination shows well-demarcated, symmetrical, erythematous plaq... | D: Dermal collagen loss |
Answer the following medical question with one of the provided options: | Q:A 25-year-old woman is brought to a psychiatrist’s office by her husband who states that he is worried about her recent behavior, as it has become more violent. The patient’s husband states that his family drove across the country to visit them and that his wife ‘threatened his parents with a knife’ at dinner last ni... | A: Schizoaffective disorder |
Answer the following medical question with one of the provided options: | Q:A 27-year-old previously healthy man presents to the clinic complaining of bloody diarrhea and abdominal pain. Sexual history reveals that he has sex with men and women and uses protection most of the time. He is febrile with all other vital signs within normal limits. Physical exam demonstrates tenderness to palpati... | E: Metronidazole and iodoquinol |
Answer the following medical question with one of the provided options: | Q:An 81-year-old man is brought to the physician by his daughter after being found wandering on the street. His daughter says that over the past several months he has been more aggressive towards friends and family. She also reports several episodes in which he claimed to see two strangers in her apartment. He sometime... | A: Lewy body deposition |
Answer the following medical question with one of the provided options: | Q:A 55-year-old woman comes to the physician because of fever, chills, headache, and nausea over the past 3 days. Nine months ago, she returned from a vacation in Indonesia where she had experienced similar symptoms and episodic fever. She was treated with chloroquine and recovered uneventfully. Her temperature is 39.1... | D: Reactivation of dormant liver stage |
Answer the following medical question with one of the provided options: | Q:A 6-month-old child is brought to the pediatrician by his parents for difficulty feeding and poor motor function. The boy was born at 39 weeks gestation via spontaneous vaginal delivery. He is up to date on all vaccines and is meeting all developmental milestones until 2 months ago. He started having trouble latching... | E: Sphingomyelinase |
Answer the following medical question with one of the provided options: | Q:A 29-year-old G1P0 woman, at 12 weeks estimated gestational age, presents for her first prenatal visit. Past medical history reveals the patient has type O+ blood and that her husband has type A+ blood. The patient is worried about the risk of her baby having hemolytic disease. Which of the following is correct regar... | E: It is a rare cause of newborn hemolytic disease |
Answer the following medical question with one of the provided options: | Q:An 80-year-old male is found dead at home and brought in for an autopsy. The patient's heart shows a diminished ventricular chamber volume and the interventricular septum appears sigmoid shaped. The left atrium appears enlarged as well. A few calcifications are seen on the undamaged aortic valves. Microscopic examina... | C: Expected age related changes |
Answer the following medical question with one of the provided options: | Q:A 39-year-old man comes to the physician because of a 4-month history of fatigue. During this period, he has also had a 7.7-kg (17-lb) weight loss, despite having a normal appetite. He is sexually active with 3 female partners and uses condoms inconsistently. An HIV screening test and confirmatory test are both posit... | C: Urolithiasis |
Answer the following medical question with one of the provided options: | Q:A 49-year-old obese woman presents with a chronic non-healing ulcer on the right medial malleolus. Past medical history is significant for type 2 diabetes mellitus, diagnosed 10 years ago, poorly managed with metformin. Review of systems is significant for a recurrent white vaginal discharge. The patient is afebrile,... | B: Reduced axonal fiber diameter and fiber density |
Answer the following medical question with one of the provided options: | Q:A 72-year-old woman is brought to the emergency department by her daughter because of left-sided weakness for 1 hour. She does not have headache or blurring of vision. She has hypertension, hypercholesterolemia, type 2 diabetes, and coronary artery disease. She has smoked one half-pack of cigarettes daily for 45 year... | C: Lipohyalinosis of lenticulostriate arteries |
Answer the following medical question with one of the provided options: | Q:A 27-year-old male is brought to the emergency room following a violent assault in which he was stabbed in the chest. The knife penetrated both the left lung and the left ventricle. Where did the knife most likely enter his chest?? {'A': 'Left seventh intercostal space in the midaxillary line', 'B': 'Left seventh int... | E: Left fifth intercostal space in the midclavicular line |
Answer the following medical question with one of the provided options: | Q:A 69-year-old man is brought to the emergency department for severe tearing lower back pain for 12 hours. The pain radiates to the flank and he describes it as 8 out of 10 in intensity. He has nausea and has vomited several times. He has no fever, diarrhea, or urinary symptoms. When he stands up suddenly, he becomes ... | E: Smoking |
Answer the following medical question with one of the provided options: | Q:A 48-year-old African American male presents to his primary care provider complaining of facial swelling. He reports a three-day history of worsening swelling primarily around his eyes. The patient’s medical history is notable for sickle cell disease and poorly controlled hypertension. The patient currently takes ena... | E: Segmental sclerosis and negative immunofluorescence and foot process effacement |
Answer the following medical question with one of the provided options: | Q:A 28-year-old man comes to the physician because of a 9-month history of sleep disturbances, restlessness, and difficulty acquiring erections. He has difficulty falling asleep and wakes up at least 3 times per night. He worries about paying his bills, failing law school, and disappointing his parents. He can no longe... | A: Buspirone |
Answer the following medical question with one of the provided options: | Q:A 27-year-old woman presents for a checkup. She is 20 weeks pregnant and has been admitted to the hospital multiple times during her pregnancy for seizures. She has a known seizure disorder but discontinued her valproic acid when she became pregnant. The patient's past medical history is otherwise unremarkable. She d... | A: Folate |
Answer the following medical question with one of the provided options: | Q:A previously healthy 4-year-old boy is brought to the physician because of blisters and redness on his neck and chest for 2 days. He has also had a fever. He is lethargic and has not eaten well since the rash appeared. He has not had coughing, wheezing, or dysuria. He is an only child and there is no family history o... | A: Staphylococcal scalded skin syndrome |
Answer the following medical question with one of the provided options: | Q:A 56-year-old woman comes to the emergency department because of a 3-day history of malaise, dysuria, blurred vision, and a painful, itchy rash. The rash began on her chest and face and spread to her limbs, palms, and soles. One week ago, she was diagnosed with trigeminal neuralgia and started on a new medicine. She ... | B: Stevens-Johnson syndrome |
Answer the following medical question with one of the provided options: | Q:A 23-year-old woman presents to her primary care physician for knee pain. The pain started yesterday and has not improved since then. The patient is generally in good health. She attends college and plays soccer for her school's team. Three days ago, she was slide tackled during a game and her leg was struck from the... | D: Medial meniscal tear |
Answer the following medical question with one of the provided options: | Q:A 67-year-old man presents to the emergency department with abdominal pain that started 1 hour ago. The patient has a past medical history of diabetes and hypertension as well as a 40 pack-year smoking history. His blood pressure is 107/58 mmHg, pulse is 130/min, respirations are 23/min, and oxygen saturation is 98% ... | C: Emergent surgical intervention |
Answer the following medical question with one of the provided options: | Q:A 15-year-old boy comes to the physician because of severe muscle cramps and pain for 3 months. He first noticed these symptoms while attending tryouts for the high school football team. Since then, he becomes easily fatigued and has severe muscle pain and swelling after 10 minutes of playing. However, after a brief ... | C: Myophosphorylase deficiency |
Answer the following medical question with one of the provided options: | Q:A 82-year-old man who is currently being managed by the internal medicine service agrees to be examined by medical students as part of their training in physical examination. He is visited by a small group of medical students under the instruction of a preceptor and allows the students to make observations. They find... | A: Left heart failure |
Answer the following medical question with one of the provided options: | Q:A 2500-g (5.5-lb) male newborn is delivered at 35 weeks' gestation to a 25-year-old woman, gravida 2, para 1. The pregnancy was complicated by oligohydramnios. Pulse oximetry on room air shows an oxygen saturation of 78%. Examination in the delivery room shows that the newborn's skin appears blue with weak cry and ir... | A: Voiding cystourethrogram |
Answer the following medical question with one of the provided options: | Q:A 5-year-old girl presents to the physician with increased muscle cramping in her lower extremities after walking extended distances. The young girl is in the 10th percentile for height. Her past medical history is notable only for a cystic hygroma detected shortly after birth. Which of the following findings is most... | D: Inferior erosion of the ribs |
Answer the following medical question with one of the provided options: | Q:A 30-year-old African American man comes to the doctor's office for an annual checkup. He feels healthy and his only concern is an occasional headache after work. Past medical history is significant for an appendectomy 10 years ago and a fractured arm playing football in high school. His mother has type 2 diabetes me... | E: Recommend weight loss, more exercise, and a salt-restricted diet. |
Answer the following medical question with one of the provided options: | Q:A 4-year-old girl is brought to the physician with a 3-month history of progressive intermittent pain and swelling involving both knees, right ankle, and right wrist. The patient has been undergoing treatment with acetaminophen and ice packs, both of which relieved her symptoms. The affected joints feel "stuck” and a... | C: Oligoarticular juvenile idiopathic arthritis |
Answer the following medical question with one of the provided options: | Q:A 28-year-old woman with a past history of type 1 diabetes presents to your office with a 2-week history of vaginal itching and soreness accompanied by a white, clumpy vaginal discharge which she says resembles cheese curds. Her last HbA1c from a month ago was 7.8%, and her last cervical cytology from 10 months ago w... | C: Hyphae |
Answer the following medical question with one of the provided options: | Q:A 33-year-old woman comes to the physician for the evaluation of bleeding from her gums for 2 weeks. These episodes occur spontaneously and are self-limiting. She has also had purplish skin lesions over her legs for 2 months. Last week, she had one episode of hematuria and watery diarrhea, both of which resolved with... | D: IgG antibodies against platelets |
Answer the following medical question with one of the provided options: | Q:A 4-year-old boy is brought to the physician by his mother because of left-sided neck swelling that has slowly progressed over the past 4 weeks. He has no history of serious illness. Temperature is 38°C (100.4°F). Physical examination shows a non-tender, mobile mass in the left submandibular region with overlying ery... | C: Color blindness |
Answer the following medical question with one of the provided options: | Q:A 14-year-old boy is brought to the pediatrician by his parents with complaints of extra teeth in his lower and upper jaws. He was born by cesarean section at full term and his birth weight was 3.6 kg (7.9 lb). Until 6 months of age, he was breastfed and after that, solid foods were started. He did not cry immediatel... | A: CGG |
Answer the following medical question with one of the provided options: | Q:A 28-year-old woman visits her physician with complaints of inability to become pregnant despite frequent unprotected sexual intercourse with her husband for over a year. She breastfed her only child until about 13 months ago, when the couple decided to have a second child. Over the past year, the patient has had onl... | C: Prolactinoma |
Answer the following medical question with one of the provided options: | Q:A 53-year-old man is admitted to the intensive care unit from the emergency department with severe pancreatitis. Overnight, he starts to develop severe hypoxemia, and he is evaluated by a rapid response team. On exam the patient is breathing very quickly and has rales and decreased breath sounds bilaterally. He is pl... | D: Intra-alveolar hyaline membrane formation |
Answer the following medical question with one of the provided options: | Q:Several weeks after starting a new medication for rheumatoid arthritis, a 44-year-old woman comes to the physician because of painful ulcers in her mouth. Oral examination shows inflammation and swelling of the tongue and oropharynx and ulcers on the buccal mucosa bilaterally. Skin examination shows soft tissue swell... | B: Inhibition of dihydrofolate reductase |
Answer the following medical question with one of the provided options: | Q:A 68-year-old man comes to the physician for a routine health maintenance examination. His wife has noticed that his left eye looks smaller than his right eye. He has had left shoulder and arm pain for 3 months. He has hypertension and coronary artery disease. Current medications include enalapril, metoprolol, aspiri... | D: CT scan of the chest |
Answer the following medical question with one of the provided options: | Q:A 28-year-old man is brought to the emergency department after his girlfriend found him twitching and jerking in the yard while gardening. Shortly after he became obtunded, emergency medical services reported 1 episode of emesis during transport. His blood pressure is 85/50 mmHg, pulse is 55/min, and respirations are... | B: Atropine and pralidoxime |
Answer the following medical question with one of the provided options: | Q:A 73-year-old female presents to you for an office visit with complaints of getting lost. The patient states that over the last several years, the patient has started getting lost in places that she is familiar with, like in her neighborhood while driving to her church. She has also has difficulty remembering to pay ... | B: Memantine |
Answer the following medical question with one of the provided options: | Q:A 65-year-old man comes to the physician because of a 10-month history of progressive shortness of breath and a cough productive of a small amount of white phlegm. Bilateral end-expiratory wheezing is heard on auscultation of the chest. Pulmonary function tests show total lung capacity that is 108% of predicted, an F... | A: Smoking cessation |
Answer the following medical question with one of the provided options: | Q:A 28-year-old woman survives a plane crash in the Arctic region of Alaska. She is unable to recover any food from the crash site but is able to melt snow into drinking water using a kettle and a lighter. A rescue helicopter finally finds her after 12 days, and she is flown to a hospital. At this time, which of the fo... | A: Acetoacetate |
Answer the following medical question with one of the provided options: | Q:A 31-year-old woman presents to the emergency department with a 2-week history of dry cough and shortness of breath on exertion. She says that she has also been feeling joint pain that has been increasing over time and is worst in the mornings. Finally, she has noticed painful swellings that have been appearing on he... | E: Noncaseating granulomas |
Answer the following medical question with one of the provided options: | Q:A 59-year-old man comes to the emergency department because of progressive abdominal swelling and shortness of breath for 1 week. He drinks 12 to 13 alcoholic beverages daily. He appears emaciated. Examination shows pallor, jaundice, hepatomegaly, gynecomastia, and a protuberant abdomen with a fluid wave and shifting... | B: Alpha-fetoprotein |
Answer the following medical question with one of the provided options: | Q:An 7-month-old boy is brought to the pediatrician by his parents due to progressively worsening weakness for the last three months. The parents also describe the boy as having an exaggerated response when startled as well as diminishing response to visual stimuli. At birth, the boy was healthy and remained as such fo... | C: Hexosaminidase A |
Answer the following medical question with one of the provided options: | Q:A 68-year-old man presents to the clinic for a regular health checkup. He is hypertensive and was diagnosed with congestive heart failure last year. He has hyperlipidemia but does not take any medication for it. Although he takes his antihypertensive medications regularly, his blood pressure recordings at home tend t... | E: Hypokalemia |
Answer the following medical question with one of the provided options: | Q:A 35-year-old female presents to her PCP at the request of her husband after 3 weeks of erratic behavior. The patient has been staying up all night online shopping on eBay. Despite a lack of sleep, she is "full of energy" during the day at her teaching job, which she believes is "beneath [her], anyway." She has not s... | C: Valproate and olanzapine |
Answer the following medical question with one of the provided options: | Q:A 10-day-old newborn is undergoing surgery for the removal of a branchial cleft cyst. Histopathology of the cyst shows squamous cells with lymphoid infiltrate and keratinaceous cellular debris embedded in adipose tissue with a high concentration of mitochondria. Which of the following substances is most likely to be ... | A: Thermogenin |
Answer the following medical question with one of the provided options: | Q:A 32-year-old physician is cleaning his pool when he splashes the hydrochloric acid in his left eye. He feels immediate pain and burning. His eye starts to tear profusely, and he can barely open it. His medical history is significant for psoriasis. He is farsighted and has glasses for reading and computer work. He us... | E: Irrigate with tap water |
Answer the following medical question with one of the provided options: | Q:A previously healthy 31-year-old woman comes to the emergency department because of sudden, severe epigastric pain and vomiting for the past 4 hours. She reports that the pain radiates to the back and began when she was having dinner and drinks at a local brewpub. Her temperature is 37.9°C (100.2°F), pulse is 98/min,... | B: Right upper quadrant abdominal ultrasound |
Answer the following medical question with one of the provided options: | Q:A 54-year-old man with a history of hyperlipidemia presents to the emergency department complaining of left sided chest pain. He says the pain began 3 hours ago while he was cooking dinner in his kitchen. The pain radiates to his left arm and stomach. He also complains of feeling anxious and heart palpitations. Tempe... | D: Irreversible ADP receptor antagonism |
Answer the following medical question with one of the provided options: | Q:A 43-year-old Caucasian female with a long history of uncontrolled migraines presents to general medical clinic with painless hematuria. She is quite concerned because she has never had symptoms like this before. Vital signs are stable, and her physical examination is benign. She denies any groin pain, flank pain, or... | A: Analgesic nephropathy |
Answer the following medical question with one of the provided options: | Q:A 38-year-old man comes to the physician because of a 2-week history of abdominal pain and an itchy rash on his buttocks. He also has fever, nausea, and diarrhea with mucoid stools. One week ago, the patient returned from Indonesia, where he went for vacation. Physical examination shows erythematous, serpiginous lesi... | A: Rhabditiform larvae on stool microscopy |
Answer the following medical question with one of the provided options: | Q:A 35-year-old woman comes to the physician because of headaches, irregular menses, and nipple discharge for the past 4 months. Breast examination shows milky white discharge from both nipples. Her thyroid function tests and morning cortisol concentrations are within the reference ranges. A urine pregnancy test is neg... | D: ↓ ↓ ↑ |
Answer the following medical question with one of the provided options: | Q:A 30-year-old woman visits her local walk-in clinic and reports more than one week of progressive shortness of breath, dyspnea on effort, fatigue, lightheadedness, and lower limb edema. She claims she has been healthy all year round except for last week when she had a low-grade fever, malaise, and myalgias. Upon exam... | A: Disruption of the dystrophin-glycoprotein complex |
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