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Answer the following medical question with one of the provided options: | Q:A 61-year-old man comes to the physician because of a 2-month history of a cough productive of clear mucoid sputum. He has smoked one pack of cigarettes daily for 33 years. Physical examination shows no abnormalities. Chest x-ray shows a 2-cm solid nodule in the periphery of the lower left lobe. A bronchial biopsy of... | C: Adenocarcinoma in situ |
Answer the following medical question with one of the provided options: | Q:A 67-year-old man with a history of diabetes mellitus type II and a previous myocardial infarction presents to your office for a routine examination. His blood pressure is found to be 180/100 mmHg. Which drug is the first-line choice of treatment for this patient's hypertension?? {'A': 'Amlodipine', 'B': 'Hydrochloro... | C: Lisinopril |
Answer the following medical question with one of the provided options: | Q:A 40-year-old overweight man presents to the office complaining of heartburn for 6 months. He describes burning in his chest brought on by meals. He has a 20 pack-year smoking history and drinks 2 glasses of red wine with dinner nightly. He denies dysphagia, odynophagia, weight loss, melena, and hematemesis. Over the... | C: Omeprazole |
Answer the following medical question with one of the provided options: | Q:A 34-year-old woman comes to the physician because of a 6-week history of depressed mood, loss of interest, and difficulty sleeping. She also has had a 4.5-kg (10-lb) weight loss during this period. She has not been as productive as before at work due to difficulty concentrating. There is no evidence of suicidal idea... | D: Raphe nucleus |
Answer the following medical question with one of the provided options: | Q:Parkinson’s disease is a progressive neurodegenerative disease. It is characterized by a loss of dopaminergic neurons in the substantia nigra pars compacta and the formation of cellular inclusions called Lewy bodies. These are composed of α-synuclein that has been bound to ubiquitin. In healthy individuals, α-synucle... | C: Proteasome |
Answer the following medical question with one of the provided options: | Q:A 23-year-old man presents to an outpatient psychiatrist complaining of anxiety and a persistent feeling that “something terrible will happen to my family.” He describes 1 year of vague, disturbing thoughts about his family members contracting a “horrible disease” or dying in an accident. He believes that he can prev... | B: Cognitive behavioral therapy and fluoxetine |
Answer the following medical question with one of the provided options: | Q:A 23-year-old man presents with a blunt force injury to the head from a baseball bat. He is currently unconscious, although his friends say he was awake and speaking with them en route to the hospital. He has no significant past medical history and takes no current medications. The vital signs include: temperature 37... | B: Mannitol |
Answer the following medical question with one of the provided options: | Q:A 5-month-old boy presents with increasing weakness for the past 3 months. The patient’s mother says that the weakness is accompanied by dizziness, sweating, and vertigo early in the morning. Physical examination shows hepatomegaly. Laboratory findings show an increased amount of lactate, uric acid, and elevated trig... | E: Glucose-6-phosphatase |
Answer the following medical question with one of the provided options: | Q:A 35-year-old alcoholic patient presents with high-output cardiac failure, tachycardia, a bounding pulse, and warm extremities. Blood work reveals vitamin deficiency. Which of the following vitamin deficiencies is most likely associated with such a clinical presentation?? {'A': 'Vitamin B12', 'B': 'Thiamine', 'C': 'N... | B: Thiamine |
Answer the following medical question with one of the provided options: | Q:A 56-year-old male with a history of hepatitis C cirrhosis status post TIPS procedure is brought in by his wife to the emergency department because he has been acting disoriented, slurring his speech, and sleeping throughout the day. On arrival the patient is afebrile and his vital signs are pulse is 87/min, blood pr... | D: Administer lactulose |
Answer the following medical question with one of the provided options: | Q:A 78-year-old woman with a history of cerebrovascular accident (CVA) presents to the emergency department with slurred speech, diplopia and dizziness that has persisted for eight hours. Upon further questioning you find that since her CVA one year ago, she has struggled with depression and poor nutrition. Her dose of... | C: Lower the dose of her anti-seizure medication |
Answer the following medical question with one of the provided options: | Q:A 1-year-old previously healthy male presents to the emergency department with 3 hours of intermittent abdominal pain, vomiting, and one episode of dark red stools. On exam, his abdomen is tender to palpation and there are decreased bowel sounds. A CT scan reveals air fluid levels and a cystic mass in the ileum. Gros... | B: Abnormal closure of the vitilline duct |
Answer the following medical question with one of the provided options: | Q:A 55-year-old woman presents to her primary care physician for a worsening cough. She states that she has had a cough for 5 months. Over the past 2 weeks, the cough has become more frequent and produces yellow sputum. She has dyspnea on exertion at baseline, which she feels is also worsening. She denies fever, hemopt... | D: Vaccination to induce a B-cell response with moderate level affinity antibodies |
Answer the following medical question with one of the provided options: | Q:A 55-year-old man visits his primary care physician for a follow-up visit. He was diagnosed with asthma during childhood, but it has always been well controlled with an albuterol inhaler. He is hypertensive and admits that he is not compliant with his antihypertensive medication. He expresses his concerns about frequ... | A: Papilledema |
Answer the following medical question with one of the provided options: | Q:A 29-year-old woman presents to the physician with a blurred vision of her right eye over the past day. She has pain around her right eye during eye movement. She has a history of tingling in her left leg 5 months ago, which spontaneously resolved after 2 weeks. She takes no medications. Her blood pressure is 110/70 ... | D: Methylprednisolone |
Answer the following medical question with one of the provided options: | Q:A 27-year-old man presents with a 2-week history of fever, malaise, and occasional diarrhea. On physical examination, the physician notes enlarged inguinal lymph nodes. An HIV screening test is positive. Laboratory studies show a CD4+ count of 650/mm3. This patient is most likely currently in which of the following s... | D: Acute HIV infection |
Answer the following medical question with one of the provided options: | Q:A 66-year old man with a 45-pack-year smoking history presents with abdominal pain and constipation. He reports that he has had a worsening cough for several months and has lost 20 pounds over this time period. You order a complete metabolic profile, which demonstrates hypercalcemia. A chest radiograph shows a centra... | B: Squamous cell carcinoma producing a peptide with hormonal activity |
Answer the following medical question with one of the provided options: | Q:A scientist is researching the long term effects of the hepatitis viruses on hepatic tissue. She finds that certain strains are oncogenic and increase the risk of hepatocellular carcinoma. However, they appear to do so via different mechanisms. Which of the following answer choices correctly pairs the hepatitis virus... | C: Hepatitis B virus - integration of viral DNA into host hepatocyte genome |
Answer the following medical question with one of the provided options: | Q:A 62-year-old man is brought to the emergency department by his wife because she thinks he has had a stroke. He has hypertension and type 2 diabetes mellitus. Current medications include enalapril and metformin. He has smoked 1 pack of cigarettes per day for the past 35 years. His blood pressure is 162/95 mm Hg. A CT... | C: Hemiballismus |
Answer the following medical question with one of the provided options: | Q:A 64-year-old woman presents to the surgical oncology clinic as a new patient for evaluation of recently diagnosed breast cancer. She has a medical history of type 2 diabetes mellitus for which she takes metformin. Her surgical history is a total knee arthroplasty 7 years ago. Her family history is insignificant. Phy... | C: Lumpectomy |
Answer the following medical question with one of the provided options: | Q:A 26-year-old male presents to the emergency room with weight loss, abdominal pain, and bloody diarrhea. He reports having intermittent bloody stools and crampy left lower quadrant abdominal pain over the past several days. He is otherwise healthy, does not smoke, and takes no medications. His family history is notab... | B: Primary sclerosing cholangitis |
Answer the following medical question with one of the provided options: | Q:A 6-year-old boy is brought to the office by his mother. She reports that her son is well but has some concerns about his overall health: he is shorter and, physically, seems less developed compared to his siblings when they were the same age. He recently started school and the mother reports that the boy’s teachers ... | A: Deficiency of uridine monophosphate synthase |
Answer the following medical question with one of the provided options: | Q:An 8-year-old boy is shifted to a post-surgical floor following neck surgery. The surgeon has restricted his oral intake for the next 24 hours. He does not have diarrhea, vomiting, or dehydration. His calculated fluid requirement is 1500 mL/day. However, he receives 2000 mL of intravenous isotonic fluids over 24 hour... | B: Capillary hydrostatic pressure |
Answer the following medical question with one of the provided options: | Q:A 42-year-old woman presents to the urgent care clinic with recurrent chest pain and pressure radiating to her jaw. ECG is obtained and shows ST-segment elevation, but her cardiac enzymes are repeatedly found to be within normal ranges. She has a heart rate of 82/min and a blood pressure of 128/76 mm Hg. Physical exa... | C: Calcium channel blockers and nitrates |
Answer the following medical question with one of the provided options: | Q:A 35-year-old man presents to the physician’s clinic due to episodic chest pain over the last couple of months. He is currently pain-free. His chest pain occurs soon after he starts to exercise, and it is rapidly relieved by rest. He recently started training for a marathon after a decade of a fairly sedentary lifest... | C: Duration of diastole |
Answer the following medical question with one of the provided options: | Q:A 56-year-old man with substernal chest pain calls 911. When paramedics arrive, they administer drug X sublingually for the immediate relief of angina. What is the most likely site of action of drug X?? {'A': 'Large arteries', 'B': 'Large veins', 'C': 'Arterioles', 'D': 'Cardiac muscle', 'E': 'Pulmonary arteries'}, | B: Large veins |
Answer the following medical question with one of the provided options: | Q:A 74-year-old woman comes to the physician for a follow-up examination. Eight months ago, she underwent an emergency cardiac catheterization with stenting for myocardial infarction. At the time of discharge, her heart configuration was normal, end-diastolic volume was 300 mL and ejection fraction was 51%. For the pas... | D: Enalapril |
Answer the following medical question with one of the provided options: | Q:A 46-year-old woman presents to her family physician for a general wellness checkup with a chief complaint of high levels of anxiety over the past year. Her anxiety has started to affect her performance at work, making her even more anxious and concerned that she will lose her job. She started psychotherapy several m... | E: Dietary supplement |
Answer the following medical question with one of the provided options: | Q:A 60-year-old woman is brought to the emergency department by ambulance after suffering a generalized tonic-clonic seizure. The seizure lasted 2 minutes, followed by a short period of unresponsiveness and loud breathing. Her blood pressure is 130/80 mm Hg, the heart rate is 76/min, and the respiratory rate is 15/min ... | C: Loss of endothelial tight junctions |
Answer the following medical question with one of the provided options: | Q:A 22-year-old nulligravid woman comes to the physician for evaluation of irregular periods. Menarche was at the age of 12 years. Her menses have always occurred at variable intervals, and she has spotting between her periods. Her last menstrual period was 6 months ago. She has diabetes mellitus type 2 and depression.... | B: Progesterone withdrawal test |
Answer the following medical question with one of the provided options: | Q:A 52-year-old man comes to the physician because of increasing weakness of his arms and legs over the past year. He has also had difficulty speaking for the past 5 months. He underwent a partial gastrectomy for gastric cancer 10 years ago. His temperature is 37.1°C (98.8°F), pulse is 88/min, and blood pressure is 118... | D: Riluzole |
Answer the following medical question with one of the provided options: | Q:A 38-year-old woman, gravida 2, para 1, at 24 weeks' gestation comes to the physician for a routine prenatal evaluation. She has no history of major medical illness and takes no medications. Fetal ultrasonography shows a cardiac defect resulting from abnormal development of the endocardial cushions. This defect is mo... | A: Atrioventricular septal defect |
Answer the following medical question with one of the provided options: | Q:Many large clinics have noticed that the prevalence of primary biliary cholangitis (PBC) has increased significantly over the past 20 years. An epidemiologist is working to identify possible reasons for this. After analyzing a series of nationwide health surveillance databases, the epidemiologist finds that the incid... | B: Improved quality of care for PBC |
Answer the following medical question with one of the provided options: | Q:A 35-year-old man presents to his primary care provider in Philadelphia with a skin rash on his right thigh. He reports that the rash appeared 3 days ago. He recently returned from a weeklong trip to his vacation home in central Pennsylvania. He denies pain, numbness, paresthesias, itchiness, or burning around the ra... | A: A |
Answer the following medical question with one of the provided options: | Q:A 14-year-old female with no past medical history presents to the emergency department with nausea and abdominal pain. On physical examination, her blood pressure is 78/65, her respiratory rate is 30, her breath has a fruity odor, and capillary refill is > 3 seconds. Serum glucose is 820 mg/dL. After starting IV flui... | A: Intravenous regular insulin |
Answer the following medical question with one of the provided options: | Q:A group of investigators are studying the effects of transcranial direct current stimulation (tDCS) on cognitive performance in patients with Alzheimer disease. A cohort of 50 patients with mild Alzheimer disease were randomized 1:1 to either tDCS or sham tDCS over the temporoparietal cortex. Both procedures were con... | B: Crossover |
Answer the following medical question with one of the provided options: | Q:A 65-year-old man is referred by his primary care provider to a neurologist for leg pain. He reports a 6-month history of progressive bilateral lower extremity pain that is worse in his left leg. The pain is 5/10 in severity at its worst and is described as a "burning" pain. He has noticed that the pain is acutely wo... | D: Magnetic resonance imaging |
Answer the following medical question with one of the provided options: | Q:A 27-year-old woman, gravida 2, para 1, at 36 weeks' gestation comes to the physician for a prenatal visit. She feels well. Fetal movements are adequate. This is her 7th prenatal visit. She had an ultrasound scan performed 1 month ago that showed a live intrauterine pregnancy consistent with a 32-week gestation with ... | D: Swab for GBS culture |
Answer the following medical question with one of the provided options: | Q:A 25-year-old man presents with jaw discomfort and the inability to open his mouth fully for about 3 days. About a week ago, he says he cut himself while preparing a chicken dinner but did not seek medical assistance. Five days after the original injury, he started noticing jaw discomfort and an inability to open his... | D: Tetanus immunoglobulin (TIG) |
Answer the following medical question with one of the provided options: | Q:A 69-year-old woman is brought to the physician by her husband because of multiple falls and difficulty maintaining balance while standing or walking over the past year. During this period, she has had blurred vision and diplopia. Her husband has had difficulty understanding her speech for the past 3 months. She has ... | C: Midbrain atrophy with intact pons |
Answer the following medical question with one of the provided options: | Q:A 22-year-old G2P1 female presents to the clinic at the beginning of her third trimester for a fetal ultrasound. The sonographer is unable to visualize any of the structures arising from the mesonephric duct. This infant is at risk for malformation of which of the following?? {'A': 'Fallopian tubes', 'B': 'Uterus', '... | E: No malformation would be expected |
Answer the following medical question with one of the provided options: | Q:A 29-year-old female is hospitalized 1 day after an endoscopic retrograde cholangiopancreatography (ERCP) because of vomiting, weakness, and severe abdominal pain. Physical examination findings include abdominal tenderness and diminished bowel sounds. A CT scan demonstrates fluid around the pancreas. Serum levels of ... | A: Calcium |
Answer the following medical question with one of the provided options: | Q:A 22-year-old woman comes to the urgent care clinic with sudden onset of severe vomiting. She had been at a picnic with her boyfriend a few hours earlier, enjoying barbecue, potato salad, and cake. Shortly thereafter, she began vomiting and has vomited 5 times in the last 3 hours. She has no prior history of symptoms... | E: Toxin ingestion from non-spore-forming organism |
Answer the following medical question with one of the provided options: | Q:A 3-day-old boy is brought to the physician by his mother because of irritability and feeding intolerance for 1 day. His temperature is 39.2°C (102.6°F). Physical examination shows a bulging anterior fontanelle. A photomicrograph of a Gram stain of the cerebrospinal fluid is shown. Further evaluation shows that the o... | A: Escherichia coli |
Answer the following medical question with one of the provided options: | Q:A 56-year-old man comes to the physician for a follow-up examination one week after a chest x-ray showed a solitary pulmonary nodule. He has no history of major medical illness. He has smoked 1 pack of cigarettes daily for the past 30 years. Physical examination shows no abnormalities. A tuberculin skin test is negat... | A: Pulmonary hamartoma |
Answer the following medical question with one of the provided options: | Q:A 74-year-old man with a history of encephalomyelitis, ataxia, and nystagmus a new diagnosis of small cell carcinoma of the lung (T2, N1, Mn/a) is admitted to the hospital due to painless loss of vision in his right eye. A full workup reveals optic neuritis and uveitis in the affected eye. Which of the following anti... | E: Anti-CV2 (CRMP5) |
Answer the following medical question with one of the provided options: | Q:A previously healthy 24-year-old man is brought to the emergency department 30 minutes after an episode of loss of consciousness. He was standing in line at a bus stop when he suddenly became tense, fell down, and lost consciousness; this was followed by 4 minutes of violent jerky movements of his arms and legs. He w... | D: Reduced serum bicarbonate |
Answer the following medical question with one of the provided options: | Q:A 21-year-old woman comes to the physician for a routine physical examination. She feels well. She is 163 cm (5 ft 4 in) tall and weighs 54 kg (120 lb); BMI is 20.3 kg/m2. Physical examination shows no abnormalities. Her fasting serum glucose concentration is 132 mg/dL. Serum insulin concentration 30 minutes after or... | A: Defect in expression of glucokinase gene |
Answer the following medical question with one of the provided options: | Q:A 67-year-old man comes to the physician because of urinary frequency, dysuria, and blood in his urine. He has also had a 4.5-kg (10-lb) weight loss over the past 3 months and has been feeling more fatigued than usual. He smoked one pack of cigarettes daily for 40 years but quit 2 years ago. A urinalysis shows 3+ blo... | A: Dysplastic cells extending into the lamina propria |
Answer the following medical question with one of the provided options: | Q:A 24-year-old woman comes to the physician for a routine health maintenance examination. She feels well. On questioning, she has had occasional morning dizziness and palpitations during the past year. She is a graduate student. She does not smoke and drinks 1–2 glasses of wine on the weekends. Her vital signs are wit... | A: Reassurance |
Answer the following medical question with one of the provided options: | Q:A 25-year-old patient is brought into the emergency department after he was found down by the police in 5 degree celsius weather. The police state the patient is a heroin-user and is homeless. The patient's vitals are T 95.3 HR 80 and regular BP 150/90 RR 10. After warming the patient, you notice his left lower leg i... | D: Reperfusion associated edema |
Answer the following medical question with one of the provided options: | Q:A 24-year-old woman comes to the physician because of excessive hair growth. She has noticed increasing numbers of dark hairs on her upper lip and on her abdomen over the past 8 years. Menarche was at the age of 13 years. Menses occur at regular 28-day intervals and last 5–6 days with moderate flow. She is sexually a... | A: Increased activity of 5-alpha reductase |
Answer the following medical question with one of the provided options: | Q:A 65-year-old woman comes to the physician for a 18-month history of gradual enlargement of her fingertips and a 2-month history of a hoarse voice. She has had decreased appetite after a respiratory tract infection 3 months ago and a 8-kg (17.6-lb) weight loss during this period. The patient has never smoked. She was... | B: Miosis |
Answer the following medical question with one of the provided options: | Q:A 72-year-old male with history of hypertension, diabetes mellitus, cluster headaches, and basal cell carcinoma presents with complaints of progressive dyspnea. He has had increasing shortness of breath, especially when going on walks or mowing the lawn. In addition, he had two episodes of extreme lightheadedness whi... | D: Colonic angiodysplasia |
Answer the following medical question with one of the provided options: | Q:A 43-year-old woman comes to the physician because of a 6-week history of hoarseness and difficulty swallowing. She also has a history of lower back pain treated with ibuprofen. She is 162 cm (5 ft 4 in) tall and weighs 77 kg (169 lb); BMI is 29 kg/m2. Her pulse is 64/min and blood pressure is 130/86 mm Hg. Physical ... | C: Collagen deposition and decreased number of follicles |
Answer the following medical question with one of the provided options: | Q:A 29-year-old man is being monitored at the hospital after cutting open his left wrist. He has a long-standing history of unipolar depressive disorder and multiple trials of antidepressants. The patient expresses thoughts of self-harm and does not deny suicidal intent. A course of electroconvulsive therapy is suggest... | E: Retrograde amnesia " |
Answer the following medical question with one of the provided options: | Q:A 770-g (1-lb 11-oz) female newborn delivered at 28 weeks' gestation develops rapid breathing, grunting, cyanosis, and subcostal retractions shortly after birth. Her mother did not receive any prenatal care. Breath sounds are decreased over both lung fields. An x-ray of the chest shows diffuse fine, reticular densiti... | B: Betamethasone |
Answer the following medical question with one of the provided options: | Q:A 52-year-old postmenopausal woman seeks evaluation at a medical clinic with complaints of back pain and increased fatigue for 6 months. For the past week, the back pain has radiated to her legs and is stabbing in nature (7/10 in intensity). There are no associated paresthesias. She unintentionally lost 4.5 kg (10.0 ... | B: Multiple myeloma |
Answer the following medical question with one of the provided options: | Q:A 74-year-old man is brought to the emergency department after he had copious amounts of blood-stained stools. Minutes later, he turned sweaty, felt light-headed, and collapsed into his wife’s arms. Upon admission, he is found to have a blood pressure of 78/40 mm Hg, a pulse of 140/min, and oxygen saturation of 98%. ... | B: Nasogastric lavage |
Answer the following medical question with one of the provided options: | Q:A 40-year-old man with persistent moderate asthma presents for a pulmonary function test. His ratio of forced expiratory volume in one second (FEV1) to forced vital capacity (FVC) is 0.69, and his FEV1 is 65% of his predicted values. What other findings can be expected in the remainder of his pulmonary function test?... | D: Increase in fractional exhalation of nitric oxide |
Answer the following medical question with one of the provided options: | Q:A 56-year-old man presents to his general practitioner with frequent episodes of facial flushing for the past 2 weeks. He says the episodes are associated with mild headaches and a sensation of fullness in his head and neck. Additionally, he has developed recurrent, often severe, itching after taking a hot shower. Th... | E: ↑ Blood viscosity, ↓ blood flow, ↓ erythropoietin |
Answer the following medical question with one of the provided options: | Q:An 8-day-old boy is brought to the physician by his mother because of vomiting and poor feeding. The pregnancy was uncomplicated, and he was born at full term. He appears pale and lethargic. Physical examination shows diffusely increased muscle tone. His urine is noted to have a sweet odor. This patient's symptoms ar... | A: Isoleucine |
Answer the following medical question with one of the provided options: | Q:A 55-year-old male smoker presents to your office with hemoptysis, central obesity, and a round face with a "moon-like" appearance. He is found to have a neoplasm near the hilum of his left lung. A biopsy of the tumor reveals small basophilic cells with finely granular nuclear chromatin (a "salt and pepper" pattern).... | D: Cisplatin and radiotherapy |
Answer the following medical question with one of the provided options: | Q:A 3-year-old girl swallowed a handful of pills after her grandmother dropped the bottle on the ground this afternoon. She presents to the ER in a very drowsy but agitated state. She is clutching her abdomen, as if in pain, her skin is dry and flushed, and she does not know her name or where she is. Her pupils are dil... | D: Physostigmine |
Answer the following medical question with one of the provided options: | Q:A 49-year-old man was brought to the emergency department by ambulance with complaints of sudden-onset chest pain that radiates into his neck and down his left arm. This substernal pain started 2 hours ago while he was having dinner. His past medical history is remarkable for hypercholesterolemia that is responsive t... | E: Right main coronary artery occlusion |
Answer the following medical question with one of the provided options: | Q:A 43-year-old man comes to the physician for a 1-week history of swelling around his eyes and decreased urination. His pulse is 87/min, and blood pressure is 152/95 mm Hg. Physical examination shows 1+ periorbital and pretibial edema. Serum studies show a urea nitrogen concentration of 21 mg/dL and a creatinine conce... | D: Red blood cell casts |
Answer the following medical question with one of the provided options: | Q:A 62-year-old woman with hypertension and type 2 diabetes mellitus comes to the physician because of increasing shortness of breath and a dry cough over the past 6 months. She has smoked 1 pack of cigarettes daily for the past 40 years. Chest auscultation shows scattered expiratory wheezes in both lung fields. Spirom... | B: Emphysema |
Answer the following medical question with one of the provided options: | Q:A 55-year-old man presents to the emergency department with a concern of having sprayed a chemical in his eye. He states he was working on his car when his car battery sprayed a chemical on his face and eye. He states his eye is currently burning. His temperature is 99.0°F (37.2°C), blood pressure is 129/94 mmHg, pul... | B: Irrigation |
Answer the following medical question with one of the provided options: | Q:A 45-year-old man presents with a persistent cough for the past month. He says it started off with a runny nose and fever, from which he recovered in a week, but he says that the cough persists after the resolution of the fever. The patient denies any expectoration, chest pain, weight loss, or breathlessness. He repo... | B: Dextromethorphan |
Answer the following medical question with one of the provided options: | Q:A 65-year-old man presents to the emergency department with shortness of breath. He was at home cleaning his yard when his symptoms began. The patient is a farmer and does not have regular medical care. He has smoked two packs of cigarettes every day for the past 40 years. The patient lives alone and admits to feelin... | E: Varenicline |
Answer the following medical question with one of the provided options: | Q:A 26-year-old African American man comes to the physician because of a 3-day history of fatigue, back pain, and dark urine. One week ago, he developed a headache and was treated with aspirin. He does not smoke or use illicit drugs. Physical examination shows conjunctival pallor. A peripheral blood smear shows erythro... | E: Transaldolase |
Answer the following medical question with one of the provided options: | Q:An investigator is studying the effect of a high-lipid diet on glucose metabolism in Wistar rats. The experimental rat group is fed a high-lipid diet while the control group is fed a low-lipid diet. Two month after initiation of the experiment, the rats in both groups are injected with insulin and serum glucose measu... | B: Increased activity of serine kinases |
Answer the following medical question with one of the provided options: | Q:A 26-year-old woman who is a medical student is undergoing evaluation after sticking herself with a needle while drawing blood from a patient. The patient’s medical history is unknown. A blood sample from the medical student is drawn and processed, and the results are presented below: Anti-HAV IgM negative Anti-HAV I... | A: She has not been vaccinated against the hepatitis B virus. |
Answer the following medical question with one of the provided options: | Q:A 47-year-old woman presents to the clinic for a regular health check-up. She is currently asymptomatic but gives a history of recurrent bouts of right upper abdominal pain for 3 years. She further describes the pain as intermittent and localized. She denies any fever, vomiting, difficulty breathing, abnormal bowel h... | D: Carcinoma of the gallbladder |
Answer the following medical question with one of the provided options: | Q:A 51-year-old man presents to the emergency department with an episode of syncope. He was at a local farmer's market when he fainted while picking produce. He rapidly returned to his baseline mental status and did not hit his head. The patient has a past medical history of diabetes and hypertension but is not current... | D: Prostate cancer |
Answer the following medical question with one of the provided options: | Q:A 15-year-old boy is brought to the emergency department with a 30 minute history of difficulty breathing. He was playing basketball in gym class when he suddenly felt pain in the right side of his chest that got worse when he tried to take a deep breath. Physical exam reveals a tall, thin boy taking rapid shallow br... | E: Found near the pleura |
Answer the following medical question with one of the provided options: | Q:A 40-year-old woman visits her physician’s office with her husband. Her husband says that she has been complaining of recurring headaches over the past few months. A year ago she was diagnosed with diabetes and is currently on treatment for it. About 6 months ago, she was diagnosed with high blood pressure and is als... | B: Serum insulin-like growth factor-1 (IGF-1) |
Answer the following medical question with one of the provided options: | Q:A Caucasian 32-year-old woman has an uncomplicated vaginal delivery, giving birth to male and female fraternal twins at term. At 2 days of life, the twin sister develops abdominal distension without emesis, and the mother states that she has not noticed the passage of stool for this infant. Genetic testing identifies... | C: 50% |
Answer the following medical question with one of the provided options: | Q:A 14-year-old male is brought to your psychiatric clinic after he was caught stealing his peers’ belongings multiple times by his teacher. He is a straight-A student with many friends and is an outstanding football player. He describes his family as very loving and gets along with his older siblings. He also states t... | D: Kleptomania |
Answer the following medical question with one of the provided options: | Q:A 56-year-old postmenopausal woman comes to the physician because of a 6-month history of worsening pain and swelling in her left knee. She has a history of peptic ulcer disease for which she takes cimetidine. Examination shows palpable crepitus and limited range of motion of the left knee. Which of the following is ... | D: Celecoxib |
Answer the following medical question with one of the provided options: | Q:A 33-year-old man is brought into the emergency department with fever, lethargy, and confusion. He is a cachectic man in acute distress, unable to respond to questions or follow commands. His friend confides that the patient has been sexually active with multiple male partners and was diagnosed with HIV several month... | E: Neurological exam with fundoscopy |
Answer the following medical question with one of the provided options: | Q:A 5-year-old boy is brought to the physician’s office with complaints of being tired constantly, which has limited his ability to walk or play with his friends. Physical examination in the physician’s office is normal. Further testing reveals that the patient has a genetic mutation in an enzyme and muscle biopsy show... | D: Vitamin B1 |
Answer the following medical question with one of the provided options: | Q:A 57-year-old man comes to the physician because of a 4-week history of constipation, episodic bloody stools, progressive fatigue, and a 5-kg (10.2-lb) weight loss. Digital rectal examination shows a hard, 1.5-cm rectal mass. A biopsy confirms the diagnosis of colorectal carcinoma. The patient begins treatment with a... | E: Vascular endothelial growth factor |
Answer the following medical question with one of the provided options: | Q:A 17-year-old high school student presents to your office for recent mood and skin changes. The patient is a high school senior who is competing on the wrestling team and recently has lost weight to drop two weight classes over the past several months. He states he has dry, cracking, and irritated skin, as well as a ... | A: Water soluble vitamin deficiency |
Answer the following medical question with one of the provided options: | Q:A 13-year-old girl is brought to the pediatrician due to a 4-month history of heavy vaginal bleeding during menstrual periods. She endorses episodes of bleeding gums after brushing her teeth and experienced prolonged bleeding after tonsillectomy 6 years ago. Her mother states that she bled significantly during childb... | E: Bernard-Soulier syndrome |
Answer the following medical question with one of the provided options: | Q:A 55-year-old man is brought to the emergency department by ambulance from a long term nursing facility complaining of severe shortness of breath. He suffers from amyotrophic lateral sclerosis and lives at the nursing home full time. He has had the disease for 2 years and it has been getting harder to breath over the... | B: Sternocleidomastoid muscles |
Answer the following medical question with one of the provided options: | Q:A 14-year-old girl is presented by her mother who says she has trouble focusing. The patient’s mother says that, over the past 2 months, the patient has lost interest in her normal activities and has become more withdrawn. She no longer participates in activities she enjoys and says that she has contemplated suicide.... | B: Lithium |
Answer the following medical question with one of the provided options: | Q:A 63-year-old man comes to the physician because of a 4-month history of urinary hesitancy and poor urinary stream. Digital rectal examination shows a symmetrically enlarged, nontender prostate. Serum studies show a prostate-specific antigen concentration of 2 ng/mL (N < 4). Pharmacotherapy with finasteride is initia... | B: Increased prostatic apoptosis |
Answer the following medical question with one of the provided options: | Q:An 85-year-old man presents to his primary care provider after feeling "lightheaded." He said he helped his wife in the garden for the first time, but that while moving some bags of soil he felt like he was going to faint. He had a big breakfast of oatmeal and eggs prior to working in the garden. He has no significan... | B: Calcification |
Answer the following medical question with one of the provided options: | Q:A 32-year-old woman presents to the office with complaints of intense anal pain every time she has a bowel movement. The pain has been present for the past 4 weeks, and it is dull and throbbing in nature. It is associated with mild bright red bleeding from the rectum that is aggravated during defection. She has no re... | D: Local anal trauma |
Answer the following medical question with one of the provided options: | Q:A 53 year-old woman with history of ulcerative colitis presents to the emergency department with a severe flare. The patient reports numerous bloody loose stools, and has been febrile for two days. Vital signs are: T 101.9 HR 98 BP 121/86 RR 17 Sat 100%. Abdominal exam is notable for markedly distended abdomen with t... | B: IV hydrocortisone |
Answer the following medical question with one of the provided options: | Q:A 26-year-old man presents into the emergency department complaining of hemoptysis for the past day. He has also experienced fatigue, weight loss (10 kg (22 lb) over the last 2 months), and occasional dry cough. He is a college student and works part-time as a cashier in a bookstore. He is sexually active with his gi... | D: Testicular malignancy |
Answer the following medical question with one of the provided options: | Q:A 46-year-old woman comes to the physician with a 4-month history of lethargy. She has had joint pain for the past 15 years and does not have a primary care physician. Her temperature is 37.4°C (99.3°F), pulse is 97/min, and blood pressure is 132/86 mm Hg. Physical examination shows pallor of the oral mucosa and nont... | A: Anti-CCP antibody |
Answer the following medical question with one of the provided options: | Q:A 59-year-old woman comes to the emergency department because of abdominal pain and bloody diarrhea that began 12 hours ago. Three days ago, she ate undercooked chicken at a local restaurant. Blood cultures grow spiral and comma-shaped, oxidase-positive organisms at 42°C. This patient is at greatest risk for which of... | A: Segmental myelin degeneration |
Answer the following medical question with one of the provided options: | Q:An 80-year-old woman presents with fatigue and a 30-lb weight loss over the past 3 months. The patient states that her symptoms started with mild fatigue about 4 months ago, which have progressively worsened. She noticed that the weight loss started about 1 month later, which has continued despite no changes in diet ... | A: Axillary lymphadenopathy |
Answer the following medical question with one of the provided options: | Q:A 55-year-old caucasian man presents to his primary care physician with a complaint of double vision, which started suddenly with no precipitating trauma. Twelve years ago, he presented to his physician with painful vision loss, which has since resolved. Since that initial episode, he had numerous episodes early-on i... | C: Initial presenting symptoms |
Answer the following medical question with one of the provided options: | Q:A 30-year-old man presents with weakness in his right hand. He says he has been an avid cyclist since the age of 20. He denies any recent trauma. Physical examination reveals decreased sensations over the 4th and 5th digits with difficulty extending the 4th and 5th phalanges. Strength is 4 out of 5 in the extensor mu... | B: Ulnar nerve |
Answer the following medical question with one of the provided options: | Q:A 28-year-old homeless male with a past medical history significant for asthma comes to your clinic complaining of a chronic rash on his scalp and feet. He describes the rash as “dry and flaky,” and reports it has been present for at least a year. He was using a new dandruff shampoo he got over the counter, with litt... | B: Culture in Sabouraud liquid medium |
Answer the following medical question with one of the provided options: | Q:A 40-year-old gravida 4 para 2 woman presents with urinary incontinence requesting definitive treatment. She started experiencing urinary incontinence when coughing, laughing, or exercising about three months ago. Symptoms have not improved with behavioral changes or Kegel exercises. Past medical history is significa... | E: Anatomic elevation of the urethra |
Answer the following medical question with one of the provided options: | Q:A vaccination campaign designed to increase the uptake of HPV vaccine was instituted in chosen counties of a certain state in order to educate parents not only about the disease itself, but also about why children should be vaccinated against this viral sexually transmitted disease. At the end of the campaign, childr... | B: Family income appears to be an effect modifier. |
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