task
stringclasses
5 values
input
stringlengths
89
339
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)c1ccc(OC)cc1 Fragment 2: [5*]N1CCOCC1 ### Response: COC(=O)c1cc(N2CCOCC2)ccc1NC(=O)c1ccc(OC)cc1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [8*]CC(=O)[O-] Fragment 2: [4*]C1([15*])CCC1 ### Response: Cc1[nH]c(=O)sc1S(=O)(=O)NC1(CC(=O)[O-])CCC1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. O=C(NCCC1=c2ccccc2=[NH+]C1)c1ccc2c(c1)[C@H](c1ccccc1)ON2 ### Response: 2
canonicalization
### Instruction: Canonicalize the following SMILES string. C1CC1[NH2+]Cc1cc(F)ccc1N1CC[NH+](CC1)C ### Response: C[NH+]1CCN(c2ccc(F)cc2C[NH2+]C2CC2)CC1
functional_group
### Instruction: Does the molecule contain a sulfonyl group? Cc1[nH]c2ccc(C(=O)NCCCn3cccn3)cc2c1C ### Response: No
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [8*]C([8*])[NH2+]C Fragment 2: [4*]C1([15*])CCC(C)CC1 ### Response: C[NH2+][C@@H](c1ccnn1C)C1(N(C)C)CCC(C)CC1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. O=C(C1CCN(CC[NH+]2CCCC2)CC1)N(Cc1ccccc1)C1CC1 ### Response: 2
canonicalization
### Instruction: Canonicalize the following SMILES string. O=C(C)NCCCCCC(N[C@H]1C[C@H](C)CCC1)=O ### Response: CC(=O)NCCCCCC(=O)N[C@@H]1CCC[C@@H](C)C1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)c1cn([9*])c(=O)c2c1c1ccccc1n2C Fragment 2: [15*]C1CCCC1 ### Response: CN1CCN(C(=O)c2cn(C3CCCC3)c(=O)c3c2c2ccccc2n3C)CC1
canonicalization
### Instruction: Canonicalize the following SMILES string. C(Cc1ccc(cc1)F)(=O)NCCn1ncc2c1ncnc2N1CCN(c2ccccc2)CC1 ### Response: O=C(Cc1ccc(F)cc1)NCCn1ncc2c(N3CCN(c4ccccc4)CC3)ncnc21
functional_group
### Instruction: Does the molecule contain a carboxyl group? O=C(NNC(=O)c1c[nH]c2ccc(Cl)cc2c1=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 ### Response: No
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(C)(C)OC(=O)N1[C@@H]2CC[C@H]1C[NH+](Cc1cccc(O)c1)CC2 ### Response: 3
functional_group
### Instruction: Does the molecule contain a amide group? COc1ccccc1C(=O)NC[C@@H](c1ccc(N(C)C)cc1)N1CCc2ccccc2C1 ### Response: Yes
canonicalization
### Instruction: Canonicalize the following SMILES string. CCOc1ccc(F)c(C(=O)NC[C@](c2cn(C)nc2)(O)C)c1F ### Response: CCOc1ccc(F)c(C(=O)NC[C@@](C)(O)c2cnn(C)c2)c1F
functional_group
### Instruction: Does the molecule contain a aromatic_ring group? CC[C@H]1Oc2ccc(C)cc2N(CC(=O)N(Cc2ccccc2)Cc2ccccn2)C1=O ### Response: Yes
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [15*][C@H]1CC[C@](CO)([NH2+]C)C1 Fragment 2: [8*]C(F)(F)F ### Response: C[NH2+][C@@]1(CO)CC[C@H](n2ccc(C(F)(F)F)n2)C1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? C[NH+]1CCN(c2ccc(Cl)cc2NC(=O)CCC2CCCCC2)CC1 ### Response: 3
ring_counting
### Instruction: Count the five-membered rings in the following molecule. O=C(Nc1ccc2c(c1)OCCO2)N1CCCCC[C@H]1c1ccccc1Cl ### Response: 0
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [14*]c1n[nH]c([14*])n1 Fragment 2: [16*]c1ccc(O)c([N+](=O)[O-])c1 ### Response: COc1cc(-c2nc(-c3ccc(O)c([N+](=O)[O-])c3)n[nH]2)cc(OC)c1OC
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [8*]Cc1sccc1Br Fragment 2: [8*]C(C)(C)C ### Response: CC(C)(C)c1nnnn1Cc1sccc1Br
ring_counting
### Instruction: Count the five-membered rings in the following molecule. [NH3+][C@@H](c1ncc[nH]1)[C@@H]1CCOC2(CCC2)C1 ### Response: 1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? Cc1ccc([C@@H](C)N[C@@H](c2nc(C3CC3)no2)C(C)C)o1 ### Response: 3
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CNc1cc(C[C@H](NC(=O)C(C)C)c2cccc(C)c2)nc(C2CC2)n1 ### Response: 3
ring_counting
### Instruction: Count the six-membered rings in the following molecule. c1ccc2c(c1)CC(c1noc(C3C[NH2+]C3)n1)C2 ### Response: 1
canonicalization
### Instruction: Canonicalize the following SMILES string. FC([C@@](O)(CCNC(Nc1sc2c(cccc2)n1)=O)c1oc(C)cc1)(F)F ### Response: Cc1ccc([C@](O)(CCNC(=O)Nc2nc3ccccc3s2)C(F)(F)F)o1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CO[C@H]1CCCN(C(=O)Nc2ccc(OC(C)C)cc2F)C1 ### Response: 0
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? COc1ccc(-c2cc(C(=O)N/N=C(\C)c3ccc([N+](=O)[O-])cc3)[nH]n2)c(OC)c1 ### Response: 2
canonicalization
### Instruction: Canonicalize the following SMILES string. O=C(N1CCCCCCC1)N[C@@H]([C@@H]1CCCO1)C ### Response: C[C@@H](NC(=O)N1CCCCCCC1)[C@@H]1CCCO1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]N1Cc2nc([14*])sc2C1 Fragment 2: [1*]C(=O)c1cccc(N[5*])c1 ### Response: O=C(Nc1cccc(C(=O)N2Cc3nc(-c4ccccc4)sc3C2)c1)c1ccsc1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(C)[NH+]1CCCN(C(=O)N[C@H]2CCC[C@@H]2CNC(=O)OC(C)(C)C)CC1 ### Response: 3
canonicalization
### Instruction: Canonicalize the following SMILES string. [C@@H]1(C(=O)[O-])[C@@H]([C@@H]2C=C[C@H]1C2)C(Nc1cc(C(C)(C)C)on1)=O ### Response: CC(C)(C)c1cc(NC(=O)[C@H]2[C@@H](C(=O)[O-])[C@H]3C=C[C@@H]2C3)no1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)N1CCN([5*])CC1 Fragment 2: [1*]C(=O)c1cccc(F)c1 ### Response: O=C(Nc1c(F)cccc1F)N1CCN(C(=O)c2cccc(F)c2)CC1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]N1CCC[C@H]1[13*] Fragment 2: [5*]N(C)C ### Response: COc1cccc([C@@H]2CCCN2C(=O)Nc2ccccc2C(=O)N(C)C)c1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]N[C@H]1c2ccccc2C(=O)N1[10*] Fragment 2: [16*]c1ccccc1[N+](=O)[O-] ### Response: CCCCN1C(=O)c2ccccc2[C@@H]1Nc1ccccc1[N+](=O)[O-]
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [4*][C@@H](C)CO Fragment 2: [15*]C1CCOCC1 ### Response: Cc1cc(NC(=O)N[C@@H](C)CO)ccc1OC1CCOCC1
functional_group
### Instruction: Does the molecule contain a amide group? C[C@H]1CCCN1C(=O)CC[NH+](C1CC1)[C@@H](C)C1CC1 ### Response: Yes
canonicalization
### Instruction: Canonicalize the following SMILES string. C(/C[NH+]1CCC(Cc2noc(C3CC3)n2)CC1)=C\c1ccco1 ### Response: C(=C\c1ccco1)/C[NH+]1CCC(Cc2noc(C3CC3)n2)CC1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)c1c(C)cc(C)[nH]c1=O Fragment 2: [1*]C(=O)c1ccncc1 ### Response: Cc1cc(C)c(C(=O)N[C@H](C)c2ccc(NC(=O)c3ccncc3)cc2)c(=O)[nH]1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]N[C@H]([8*])C Fragment 2: [14*]c1ccco1 ### Response: C[C@H](NC(=O)c1cc(-c2ccco2)on1)[C@H]1CCCO1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [14*]c1ccc(C)s1 Fragment 2: [1*]C(=O)C[8*] ### Response: Cc1ccc(-c2csc3ncn(CC(=O)Nc4ccc(F)cc4F)c(=O)c23)s1
functional_group
### Instruction: Does the molecule contain a aldehyde group? C#CCOc1c(Cl)cc(/C=C2/C(=O)N(c3ccc(F)cc3)C(=O)N=C2[O-])cc1OC ### Response: No
functional_group
### Instruction: Does the molecule contain a ether group? O=C(/C=C/c1ccncc1)c1cccc([N+](=O)[O-])c1 ### Response: No
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? Cc1cc(C)c2c(NCC3(Cn4cc[nH+]c4C)CC3)ncnc2n1 ### Response: 1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]NC1CC1 Fragment 2: [5*]N1CC[NH+]([5*])CC1 ### Response: N#C[C@@]1(NC2CC2)CC[C@@H](N2CC[NH+](CC3CC3)CC2)C1
functional_group
### Instruction: Does the molecule contain a aldehyde group? COc1cccc(Oc2ccc(CNC(=O)/C=C/C(C)(C)C)cn2)c1 ### Response: No
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CCCC(=O)N1CCC[C@@H]1C(=O)O[C@H](C)c1cccc(F)c1 ### Response: 1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CCCCN(C)C(=O)c1ccccc1S(=O)(=O)[N-]c1cc(C)ccc1F ### Response: 0
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*][NH2+]Cc1ccccc1Br Fragment 2: [4*]C[C@@H](C)C[C@@H](C)O ### Response: C[C@H](C[NH2+]Cc1ccccc1Br)C[C@@H](C)O
functional_group
### Instruction: Does the molecule contain a phenol group? C[C@@H](Oc1ccc(Cl)cc1Cl)C(=O)NC[C@@H](c1cccs1)[NH+](C)C ### Response: No
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CC(C)[C@@H]1SC[C@@H](C(=O)[O-])N1C(=O)COCC[NH3+] ### Response: 1
functional_group
### Instruction: Does the molecule contain a amide group? CON(C)C(=O)[C@H]1CCCCN1C(=O)OC(C)(C)C ### Response: Yes
functional_group
### Instruction: Does the molecule contain a nitro group? Cc1cc(NC(=O)C2CCN(C(=O)C(C)(C)C)CC2)n(-c2ccc([N+](=O)[O-])cc2)n1 ### Response: Yes
functional_group
### Instruction: Does the molecule contain a phenol group? Cc1ccc(CNC(=O)C[NH+]2CC(c3nc(-c4ncccn4)no3)C2)cc1 ### Response: No
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CCC(C)(C)OC[C@H](CS)C(C)(C)C ### Response: 0
functional_group
### Instruction: Does the molecule contain a aromatic_ring group? COc1cccc(C[C@@H](NCc2ncn(C)n2)c2ccccc2)c1 ### Response: Yes
functional_group
### Instruction: Does the molecule contain a ether group? O=C(c1cc(C2CC2)nc2ccccc12)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCCO3)CC1 ### Response: Yes
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)[C@@H]1C[C@@H](O)CN1[5*] Fragment 2: [1*]C(=O)[C@@H]1C[C@@H](O)CN1C([1*])=O ### Response: Cc1cc(NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)OCC(C)C)ccc1I
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? C[C@H]1c2cccn2CC[NH+]1CC(=O)Nc1ccc(S(C)(=O)=O)cc1 ### Response: 2
canonicalization
### Instruction: Canonicalize the following SMILES string. [NH2+](Cc1c(n(nc1)-c1ccc(cc1)Cl)CCC)CCC ### Response: CCC[NH2+]Cc1cnn(-c2ccc(Cl)cc2)c1CCC
functional_group
### Instruction: Does the molecule contain a amide group? C[S@@](=O)c1ccc(C[NH+]2CCC(OC[C@H]3CCCO3)CC2)cc1 ### Response: No
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [4*]Cc1cc(C)on1 Fragment 2: [1*]C(=O)CC[4*] ### Response: Cc1cc(CSCCC(=O)N2CCN(c3ncccn3)CC2)no1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1cccc(N2CCCCC2)c1NC(=O)[C@H]1ON=C(C1)c1ccc(Cl)s1 ### Response: O=C(Nc1ccccc1N1CCCCC1)[C@@H]1CC(c2ccc(Cl)s2)=NO1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1c(C)c(cc(c1C[NH+](C)C(C1CC1)C1CC1)O)C ### Response: Cc1cc(O)c(C[NH+](C)C(C2CC2)C2CC2)cc1C
ring_counting
### Instruction: Count the six-membered rings in the following molecule. Cc1ccc(NC(=O)CN(C)C(=O)c2cc3ccccc3s2)cc1 ### Response: 2
functional_group
### Instruction: Does the molecule contain a phenol group? CC[NH+]1CC[C@@H]([NH2+]C[C@@H]2CCCO[C@@H]2C(C)C)[C@H](C)C1 ### Response: No
ring_counting
### Instruction: Count the five-membered rings in the following molecule. C[C@H](CNC(=O)N1C[C@H]2CCCC[NH+]2C[C@@H]1C)C(=O)[O-] ### Response: 0
canonicalization
### Instruction: Canonicalize the following SMILES string. c1c(OC)c(cc(C[NH2+][C@H](c2ccc(cc2)F)C)c1Br)OC ### Response: COc1cc(Br)c(C[NH2+][C@@H](C)c2ccc(F)cc2)cc1OC
functional_group
### Instruction: Does the molecule contain a halide group? CN(C)S(=O)(=O)N(C)[C@H]1CCN(c2ccccc2Cl)C1=O ### Response: Yes
functional_group
### Instruction: Does the molecule contain a amine group? C[C@@H](c1ccccc1)[NH+](C)CCOc1ccc(C#N)cc1 ### Response: No
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [3*]OC(F)(F)F Fragment 2: [16*]c1ccc([16*])cc1 ### Response: C[C@@H](NC(=O)c1cccc2cn[nH]c12)c1ccc(OC(F)(F)F)cc1
canonicalization
### Instruction: Canonicalize the following SMILES string. N(C)(C)c1nc(c(s1)C[NH+]([C@H]1CCCc2n(C)ncc12)C)C ### Response: Cc1nc(N(C)C)sc1C[NH+](C)[C@H]1CCCc2c1cnn2C
ring_counting
### Instruction: Count the five-membered rings in the following molecule. Cc1cc(CN2C[C@@H](C)O[C@H](C(N)=O)C2)c(C)n1C1CC1 ### Response: 1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [4*]Cc1ccnc([14*])c1 Fragment 2: [4*]Cc1ccc(C)nc1 ### Response: Cc1ccc(CNC(=O)NCc2ccnc(OC(C)(C)C)c2)cn1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [16*]c1cc(C)sc1C Fragment 2: [13*][C@H]1OCCC[C@H]1CCl ### Response: Cc1cc([C@H]2OCCC[C@H]2CCl)c(C)s1
functional_group
### Instruction: Does the molecule contain a amine group? COc1ccc(NC(=O)C(=O)Nc2c[nH]nc2C)cc1F ### Response: No
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? Cc1n[nH]c([C@@H]2CN(C(=O)[C@H](C)c3cccs3)CCO2)n1 ### Response: 3
canonicalization
### Instruction: Canonicalize the following SMILES string. c1cccc(c1C(=O)NCCS(=O)(/N=c1\[nH]cccc1)=O)OCC ### Response: CCOc1ccccc1C(=O)NCCS(=O)(=O)/N=c1/cccc[nH]1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. O=C(c1ccco1)N1CCN(C(=O)[C@@H]2CCCN(c3nnc(-n4cccc4)s3)C2)CC1 ### Response: 3
canonicalization
### Instruction: Canonicalize the following SMILES string. CC1([C@@]2([C@@H](C[C@H]1CC2)[NH2+]Cc1ccccc1O)C)C ### Response: CC1(C)[C@@H]2CC[C@@]1(C)[C@H]([NH2+]Cc1ccccc1O)C2
canonicalization
### Instruction: Canonicalize the following SMILES string. c1c(NC(C(c2cccc(c2)C#N)(C)C)=O)cccc1[C@H](OC)C ### Response: CO[C@H](C)c1cccc(NC(=O)C(C)(C)c2cccc(C#N)c2)c1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1c(cccc1)Nc1c2ccccc2nc(SCC(Nc2noc(c2)C)=O)n1 ### Response: Cc1cc(NC(=O)CSc2nc(Nc3ccccc3)c3ccccc3n2)no1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)c1cccc([16*])c1 Fragment 2: [1*]C(=O)c1cccc(N[5*])c1 ### Response: COc1ccc(S(=O)(=O)Nc2cccc(C(=O)Nc3ccc(Cl)cc3)c2)cc1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. c1cn(C[C@H]2CCC[NH+](Cc3ccoc3)C2)nn1 ### Response: 2
ring_counting
### Instruction: Count the five-membered rings in the following molecule. Cc1ccc(N[C@H](C)CC(C)C)c([N+](=O)[O-])c1 ### Response: 0
canonicalization
### Instruction: Canonicalize the following SMILES string. c1c(Oc2c(SC)cccc2)c(c(cc1N)S(N)(=O)=O)C ### Response: CSc1ccccc1Oc1cc(N)cc(S(N)(=O)=O)c1C
ring_counting
### Instruction: Count the six-membered rings in the following molecule. Cc1cc(C)n2nc(C)c(C(=O)Nc3cc([N+](=O)[O-])ccc3O)c2n1 ### Response: 2
canonicalization
### Instruction: Canonicalize the following SMILES string. [S@@](Cc1ccc(F)cc1)([C@H](C(=O)NCc1ccc(cc1)Cl)C)=O ### Response: C[C@@H](C(=O)NCc1ccc(Cl)cc1)[S@@](=O)Cc1ccc(F)cc1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]Nc1cncc(Cl)n1 Fragment 2: [16*]c1cc(C)oc1C ### Response: Cc1cc([C@](C)(O)CNc2cncc(Cl)n2)c(C)o1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)[C@@H](C)N[5*] Fragment 2: [1*]C(=O)C([1*])=O ### Response: CCc1nn(C)cc1NC(=O)C(=O)N[C@H](C)C(=O)NCc1ccco1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [13*][C@H]1Nc2c(Br)cccc2[C@@H]2C=CC[C@@H]12 Fragment 2: [16*]c1ccccc1 ### Response: Brc1cccc2c1N[C@H](c1ccccc1)[C@@H]1CC=C[C@@H]21
functional_group
### Instruction: Does the molecule contain a ester group? COC(=O)c1ccccc1Nc1ncnc(Nc2ccc(F)c(F)c2)c1[N+](=O)[O-] ### Response: Yes
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? C/C(=N/Nc1nc(SCC(=O)Nc2ccc(C)cc2C)n[nH]1)c1ccncc1 ### Response: 2
canonicalization
### Instruction: Canonicalize the following SMILES string. c1(cc(ccc1Cl)Cl)NC(=O)C[S@@](CC)=O ### Response: CC[S@@](=O)CC(=O)Nc1cc(Cl)ccc1Cl
functional_group
### Instruction: Does the molecule contain a nitro group? CC1(C)NC(=O)N(C[C@H](O)CN2CCN([C@@H]3CCS(=O)(=O)C3)CC2)C1=O ### Response: No
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? COc1cc(C2=Nn3c(nnc3-c3ccc(C)cc3)SC2)cc(OC)c1OC ### Response: 1
functional_group
### Instruction: Does the molecule contain a aromatic_ring group? Cc1nc2ccccc2n1C[C@H]1CN(C(C)C)CCO1 ### Response: Yes
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? O=C(Nc1cccc(N2CCCCCC2)c1)N[C@H]1CC[NH+](CC2CC2)C1 ### Response: 1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CCC[NH2+][C@@H](CC)c1ccn(C[C@@H]2CN(C)CCO2)c1 ### Response: 3
functional_group
### Instruction: Does the molecule contain a amide group? CNC(=O)c1cccc(CCNc2cc(C)c3ccccc3[nH+]2)c1 ### Response: Yes
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? COc1cccc(/C(C)=C/C(=O)Oc2ccc(N(C)C(N)=O)cc2)c1 ### Response: 4