text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
[ adaptation syndrome in the development of traumatic disease in closed abdominal injuries and the principles of intensive pathogenetic therapy ] . | NA | {
"id": "C0043251",
"name": "traumatic disease",
"pos": [
44,
61
]
} | {
"id": "C0848377",
"name": "abdominal",
"pos": [
72,
81
]
} |
[ pathogenesis and treatment of pulmonary hemorrhages and hemoptysis in tuberculosis ( a review of the literature ) ] . | NA | {
"id": "C0019080",
"name": "hemorrhages",
"pos": [
42,
53
]
} | {
"id": "C0019079",
"name": "hemoptysis",
"pos": [
58,
68
]
} |
the excretion and metabolism of [ 2- ( 14 ) c ] cimetidine ( 500 mg orally ) was studied in five male volunteers . | NA | {
"id": "C0221102",
"name": "excretion",
"pos": [
4,
13
]
} | {
"id": "C0025519",
"name": "metabolism",
"pos": [
18,
28
]
} |
bacterial endotoxin , a soluble lipopolysaccharide , has been studied to ascertain its effects in vivo and in vitro on the hepatic drug-metabolizing enzymes of adult male and female rats . | NA | {
"id": "C0014264",
"name": "bacterial endotoxin",
"pos": [
0,
19
]
} | {
"id": "C0023810",
"name": "lipopolysaccharide",
"pos": [
32,
50
]
} |
in contrast to methylotrophic bacteria investigated up to now the facultative methylotrophic bacterium mb 58 ( acetobactersp . mb 58 ) does not possess a cytochrome aa3-complex , but we could find out cytochrome , cytochrome cco , cytochrome a1 , and moreover cytochrome d in dependence on the growth conditions . | NA | {
"id": "C0010798",
"name": "cytochrome",
"pos": [
154,
164
]
} | {
"id": "C0056960",
"name": "cytochrome d",
"pos": [
260,
272
]
} |
the addition of cyanide to the oxidized suspension of bacteria during the registration of the cytochrome-redox-difference spectrum allowed the selective representation of cytochrome d under all conditions even if no identification was possible in the spectrum normally . | NA | {
"id": "C0010798",
"name": "cytochrome",
"pos": [
94,
104
]
} | {
"id": "C0056960",
"name": "cytochrome d",
"pos": [
171,
183
]
} |
the application of antihyperuraemic drugs corresponding to types should be performed by uricostatic drugs , uricosuric drugs and citric acid-citrate mixtures . | NA | {
"id": "C0055819",
"name": "citric",
"pos": [
129,
135
]
} | {
"id": "C0008857",
"name": "citrate",
"pos": [
141,
148
]
} |
in order to find out the optimum method for the proof of infiltrates of malignant lymphomas in the bone marrow the frequencies of positive findings of the marrow in 41 patients with hodgkin 's disease and 89 patients with a malignant non-hodgkin-lymphoma which were established by sternal puncture , cytology of the ilia... | NA | {
"id": "C0024299",
"name": "malignant lymphomas",
"pos": [
72,
91
]
} | {
"id": "C0019829",
"name": "hodgkin 's disease",
"pos": [
182,
200
]
} |
in order to find out the optimum method for the proof of infiltrates of malignant lymphomas in the bone marrow the frequencies of positive findings of the marrow in 41 patients with hodgkin 's disease and 89 patients with a malignant non-hodgkin-lymphoma which were established by sternal puncture , cytology of the ilia... | NA | {
"id": "C0024299",
"name": "malignant lymphomas",
"pos": [
72,
91
]
} | {
"id": "C0024305",
"name": "malignant non-hodgkin-lymphoma",
"pos": [
224,
254
]
} |
own experience has shown its high efficacy in pityriasis versicolor , mycoses due to dermatophytes , skin and mucous membrane candidoses and chronic mucocutaneous candidosis syndromes . | NA | {
"id": "C0006840",
"name": "candidoses",
"pos": [
126,
136
]
} | {
"id": "C0006845",
"name": "chronic mucocutaneous candidosis",
"pos": [
141,
173
]
} |
they were followed by intra-operative bleeding in 2.6 per cent of the cases and postoperative bleeding in 1.6 per cent . | NA | {
"id": "C0019080",
"name": "bleeding",
"pos": [
38,
46
]
} | {
"id": "C0032788",
"name": "postoperative bleeding",
"pos": [
80,
102
]
} |
esr studies on the interaction of spin-labeled polynucleotides with ribosomes require a sufficient label-to-nucleotide ratio . | NA | {
"id": "C0032550",
"name": "polynucleotides",
"pos": [
47,
62
]
} | {
"id": "C0028630",
"name": "nucleotide",
"pos": [
108,
118
]
} |
compared to paraoxon these antisera possessed cross reactivities with parathion of 8.8 to 13.8 % , with methylparathion of 0.35 to 0.82 % , and with dimethoat of 0.0006 to 0.0012 % . | NA | {
"id": "C0030514",
"name": "parathion",
"pos": [
70,
79
]
} | {
"id": "C0025709",
"name": "methylparathion",
"pos": [
104,
119
]
} |
we have earlier shown that patients with severe burns develop hypophosphataemia irrespective of such causes , and have introduced the theory that hypophosphataemia can result from the humoral response to trauma . | NA | {
"id": "C0006434",
"name": "burns",
"pos": [
48,
53
]
} | {
"id": "C0043251",
"name": "trauma",
"pos": [
204,
210
]
} |
the changes in plasma insulin ( iri ) glucagon ( irg ) , iri : irg ration , growth hormone ( hgh ) , cortisol and thyroid hormones during two different but isocaloric parenteral nutrition regimens were investigated in 11 malnourished patients and 21 postoperative patients . | NA | {
"id": "C0037663",
"name": "growth",
"pos": [
76,
82
]
} | {
"id": "C3714500",
"name": "hgh",
"pos": [
93,
96
]
} |
22 patients with radiolucid stones and functioning gallbladder were grouped to establish ursodeoxycholic acid efficacy ( i.e . gallstones dissolution ) and innocuousness for gallbladder lithiasis . | NA | {
"id": "C0006736",
"name": "stones",
"pos": [
28,
34
]
} | {
"id": "C0008350",
"name": "gallstones",
"pos": [
127,
137
]
} |
in patients with igg myeloma there was correlation between measured and calculated tcm as well as measured tcm and serum igg paraprotein concentration , urine bence-jones protein excretion , and serum albumin concentration . | NA | {
"id": "C0030490",
"name": "paraprotein",
"pos": [
125,
136
]
} | {
"id": "C0004965",
"name": "bence-jones protein",
"pos": [
159,
178
]
} |
the glioblastomas ( 4 ) and astrocytomas ( 4 ) all showed hyperemia in the tumor and tumor-near region . | NA | {
"id": "C0017636",
"name": "glioblastomas",
"pos": [
4,
17
]
} | {
"id": "C0004114",
"name": "astrocytomas",
"pos": [
28,
40
]
} |
the pharmacologic blocking activity of skf-7265 was assessed by measuring blockade of the cardiovascular agonist responses induced by norepinephrine , epinephrine , isoproterenol , acetylcholine and histamine . | NA | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
134,
148
]
} | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
151,
162
]
} |
ingravescent muscular atrophy was demonstrated with a progressive decrease in the fiber diameter and changes in the fiber type distribution with predominant type ii atrophy in the first stage and type i atrophy in the later stage of the cord transection . | NA | {
"id": "C0026846",
"name": "muscular atrophy",
"pos": [
13,
29
]
} | {
"id": "C0333641",
"name": "atrophy",
"pos": [
203,
210
]
} |
clinically sized specimens were produced from one type iii gold casting alloy in combination with two different wrought wire precious alloys . | NA | {
"id": "C0018027",
"name": "gold",
"pos": [
59,
63
]
} | {
"id": "C0002154",
"name": "alloys",
"pos": [
134,
140
]
} |
the comparative multiple-dose intraocular pressure responses of nadolol and timolol in glaucoma and ocular hypertension . | NA | {
"id": "C0017601",
"name": "glaucoma",
"pos": [
87,
95
]
} | {
"id": "C0028840",
"name": "ocular hypertension",
"pos": [
100,
119
]
} |
in a double-masked clinical study the relationship between acute and chronic iop responses to topical nadolol 2 % solution and timolol 0.25 % solution twice daily was investigated in 10 patients with glaucoma or ocular hypertension . | NA | {
"id": "C0017601",
"name": "glaucoma",
"pos": [
200,
208
]
} | {
"id": "C0028840",
"name": "ocular hypertension",
"pos": [
212,
231
]
} |
a closer correlation between colour vision defects and vep latency changes was found for the on ( + ) than the on ( - ) group , suggesting demyelinating disease as a more probable cause of the optic nerve inflammation in the former than in the latter group . | NA | {
"id": "C0029134",
"name": "on",
"pos": [
18,
20
]
} | {
"id": "C0029132",
"name": "disease",
"pos": [
153,
160
]
} |
no statistically significant difference in the pressure lowering effect was found between glaucoma and ocular hypertension . | NA | {
"id": "C0017601",
"name": "glaucoma",
"pos": [
90,
98
]
} | {
"id": "C0028840",
"name": "ocular",
"pos": [
103,
109
]
} |
normal or reduced glucose tolerance in spite of the apparent hyperinsulinaemia and the negative correlation between fasting insulin level and kg in the nonhypertriglyceridaemic obese group was the marker of insulin resistance in overweight children . | NA | {
"id": "C0020459",
"name": "hyperinsulinaemia",
"pos": [
61,
78
]
} | {
"id": "C0021655",
"name": "insulin resistance",
"pos": [
207,
225
]
} |
this study described the absorption of na , k , cl , h2o and sugars from an isosmotic sucrose electrolyte solution and compares it with the absorption of these substances from an isosmotic glucose electrolyte solution and a mannitol electrolyte solution , by an in vivo perfusion technique in the rat jejunum and ileum . | NA | {
"id": "C0242209",
"name": "sugars",
"pos": [
61,
67
]
} | {
"id": "C0038636",
"name": "sucrose",
"pos": [
86,
93
]
} |
this study described the absorption of na , k , cl , h2o and sugars from an isosmotic sucrose electrolyte solution and compares it with the absorption of these substances from an isosmotic glucose electrolyte solution and a mannitol electrolyte solution , by an in vivo perfusion technique in the rat jejunum and ileum . | NA | {
"id": "C0013832",
"name": "electrolyte",
"pos": [
94,
105
]
} | {
"id": "C0308944",
"name": "electrolyte solution",
"pos": [
233,
253
]
} |
( mean +/- s.d . ) , apo a-ii 111 +/- 14 a.u . and apo b 100 +/- 34 a.u . | NA | {
"id": "C0085202",
"name": "apo a-ii",
"pos": [
21,
29
]
} | {
"id": "C0003592",
"name": "apo",
"pos": [
51,
54
]
} |
in diabetics apo a-ii was 116 +/- 14 a.u . and apo b 106 +/- 21 a.u. , values not significantly different from those in the controls . | NA | {
"id": "C0085202",
"name": "apo a-ii",
"pos": [
13,
21
]
} | {
"id": "C0003592",
"name": "apo",
"pos": [
47,
50
]
} |
the presence of ica or the duration of diabetes showed no correlation with other autoantibodies . | NA | {
"id": "C0003241",
"name": "ica",
"pos": [
16,
19
]
} | {
"id": "C0004358",
"name": "autoantibodies",
"pos": [
81,
95
]
} |
the concentration of lipids , lipoproteins and apolipoprotein b and c-iii in the serum from blood collected 4 days after birth did not practically differ from that of adult . | NA | {
"id": "C0023779",
"name": "lipids",
"pos": [
21,
27
]
} | {
"id": "C0023820",
"name": "lipoproteins",
"pos": [
30,
42
]
} |
the phenobarbital/primidone ratio ( mean 0.84 ) and pema/primidone ratio ( mean 0.56 ) in pregnant patients were found to be lower than in non-pregnant patients , except when primidone was given in combination with phenytoin in which case the expected phenobarbital/primidone ( mean 2.5 ) and pema/primidone ( mean 1.5 )... | NA | {
"id": "C0031412",
"name": "phenobarbital",
"pos": [
4,
17
]
} | {
"id": "C0033148",
"name": "primidone",
"pos": [
298,
307
]
} |
human milk and formulas with different quantities and qualities of protein were compared by measuring sequential postprandial changes in total amino acids and glycine/valine ratios in plasma of 23 healthy term neonates who had previously been breast-fed ad libitum . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
143,
154
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
159,
166
]
} |
after the feed , the sum of plasma free amino acids rose and the glycine/valine ratio fell , these changes being significant as soon as 30 min after the start of feeding and maximal at 30 min after human milk but at 60 min after the formulas . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
40,
51
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
65,
72
]
} |
the importance of neonatal asphyxia and caesarean section as risk factors for neonatal respiratory disorders in an unselected population . | NA | {
"id": "C0004045",
"name": "neonatal asphyxia",
"pos": [
18,
35
]
} | {
"id": "C0021290",
"name": "neonatal",
"pos": [
78,
86
]
} |
46 consecutively born term infants with a birthweight less than or equal to 2.3 percentile for gestational age were divided into two groups according to their nutritional status at birth quantified by the ponderal index ( 100 x weight/lenght ) . | NA | {
"id": "C0005612",
"name": "infants",
"pos": [
27,
34
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
228,
234
]
} |
the tumor arose from the left atrium and was histologically composed of multiple mesenchymal elements of fibrosarcoma , rhabdomyosarcoma , chondrosarcoma , myosarcoma , and liposarcoma . | NA | {
"id": "C0035412",
"name": "rhabdomyosarcoma",
"pos": [
120,
136
]
} | {
"id": "C0027095",
"name": "myosarcoma",
"pos": [
156,
166
]
} |
nemaline myopathy was first reported in 1963 and has been considered to be a congenital , non-progressive myopathy with weakness since birth . | NA | {
"id": "C0206157",
"name": "nemaline myopathy",
"pos": [
0,
17
]
} | {
"id": "C0752282",
"name": "congenital",
"pos": [
77,
87
]
} |
fusobacterium nucleatum atcc 10953 lps was split by hydrolysis with 1 per cent acetic acid into acid-soluble polysaccharide and lipid a . | NA | {
"id": "C0023810",
"name": "lps",
"pos": [
35,
38
]
} | {
"id": "C0023767",
"name": "lipid a",
"pos": [
128,
135
]
} |
sonication of enterotoxin-producing e. coli cells gave detectable toxin concentrations , which correlated well with the results obtained using culture broth supernatants for toxin detection in the elisa . | NA | {
"id": "C0014372",
"name": "enterotoxin",
"pos": [
14,
25
]
} | {
"id": "C0040549",
"name": "toxin",
"pos": [
174,
179
]
} |
immune complexes of horseradish peroxidase ( hrp ) and rabbit igg antibodies to hrp were used to study the fc gamma receptors in the human central nervous system ( cns ) . | NA | {
"id": "C0003313",
"name": "immune complexes",
"pos": [
0,
16
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
66,
76
]
} |
renal tubular secretion and effects of chlorothiazide , hydrochlorothiazide and clopamide : a study in the avian kidney . | NA | {
"id": "C0008273",
"name": "chlorothiazide",
"pos": [
39,
53
]
} | {
"id": "C0020261",
"name": "hydrochlorothiazide",
"pos": [
56,
75
]
} |
the relationship between renal tubular secretion and saluretic effects of two thiazides ( chlorothiazide and hydrochlorothiazide ) and clopamide was studied using a modified sperber technique . | NA | {
"id": "C0008273",
"name": "chlorothiazide",
"pos": [
90,
104
]
} | {
"id": "C0020261",
"name": "hydrochlorothiazide",
"pos": [
109,
128
]
} |
for hydrochlorothiazide , and especially for chlorothiazide the saluretic effect therefore appears to be largely independent of the tubular fluid concentration of the diuretic and primarily evoked from the peritubular side of the avian nephron . | NA | {
"id": "C0020261",
"name": "hydrochlorothiazide",
"pos": [
4,
23
]
} | {
"id": "C0008273",
"name": "chlorothiazide",
"pos": [
45,
59
]
} |
fla-63 inhibited the low-km enzyme in vitro , but much less than the aldh-inhibitors disulfiram and cyanamide . | NA | {
"id": "C2917344",
"name": "aldh-inhibitors",
"pos": [
69,
84
]
} | {
"id": "C0012772",
"name": "disulfiram",
"pos": [
85,
95
]
} |
at concentrations of 20 micrograms/ml of sulfinpyrazone and above 50 micrograms/ml of the displacing agent significant displacement was demonstrated with phenylbutazone , tolbutamide and salicylic acid . | NA | {
"id": "C0038742",
"name": "sulfinpyrazone",
"pos": [
41,
55
]
} | {
"id": "C0031463",
"name": "phenylbutazone",
"pos": [
154,
168
]
} |
in intact cats , hemorrhage caused very marked elevations of arterial plasma glucose , adrenaline , noradrenaline , dopamine , lactate , camp , glycerol and glucagon concentrations whereas plasma insulin fell to only 20 % of control values . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
87,
97
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
100,
113
]
} |
adrenalectomy attenuated the glucose , adrenaline , noradrenaline and camp responses whereas the normal insulin inhibition was abolished . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
39,
49
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
52,
65
]
} |
oxygen uptake , respiratory exchange ratio ( r ) , heart rate and arterial plasma concentrations of adrenaline , noradrenaline , dopamine , insulin , glucose , lactate , free fatty acids ( ffa ) , glycerol and beta-hydroxybutyrate were measured at rest and during exercise . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
100,
110
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
113,
126
]
} |
at rest arterial plasma noradrenaline and adrenaline levels were similar on the two diets ( 0.70 +/- 0.31 nm noradrenaline and 0.35 +/- 0.32 nm adrenaline one the carbohydrate rich diet , mean values +/- sd ) . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
24,
37
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
144,
154
]
} |
infusions of adrenaline or noradrenaline did not mimick the effect on gastrin release induced by clamping of the carotid arteries . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
13,
23
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
27,
40
]
} |
gel filtration analysis of the beta-endorphin immunoreactivity in tissue extracts and plasma showed that anterior pituitary and plasma contain three immunoreactive components , eluting like beta-endorphin , beta-lipotropin and proopiocortin , whereas only beta-endorphin-like material was detected in posterior pituitary... | NA | {
"id": "C0023832",
"name": "beta-lipotropin",
"pos": [
207,
222
]
} | {
"id": "C0033195",
"name": "proopiocortin",
"pos": [
227,
240
]
} |
decrease of plasma somatostatin-like immunoreactivity and increase of gastrin and insulin levels in peripheral venous blood of conscious dogs following infusions of pentagastrin . | NA | {
"id": "C0017151",
"name": "gastrin",
"pos": [
70,
77
]
} | {
"id": "C0030859",
"name": "pentagastrin",
"pos": [
165,
177
]
} |
spontaneous activity responses to acetylcholine ( ach ) , adrenaline ( a ) , noradrenaline ( na ) and barium chloride as well as the effects of various autonomic drugs on effects of field stimulation of nerves and muscle cells of isolated pieces or strips of cauda epididymidis , vas deferens , ampulla ductus deferentis... | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
58,
68
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
77,
90
]
} |
it was found that noradrenaline as well as adrenaline caused a significant decrease in blood flow when 10 micrograms was injected . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
18,
31
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
43,
53
]
} |
we conclude that somatostatin efficiently inhibits insulin secretion during selective alpha 1- and alpha 2-adrenoceptor blockade and , further , that the insulin off-response after somatostatin treatment is potentiated by alpha-adrenoceptor blockade . | NA | {
"id": "C0001639",
"name": "alpha 2-adrenoceptor",
"pos": [
99,
119
]
} | {
"id": "C0034784",
"name": "alpha-adrenoceptor",
"pos": [
222,
240
]
} |
survival following an intensive chemotherapy in patients with bone marrow metastasis was substantially longer for those with small cell carcinoma than for those with other histologic types of bronchogenic carcinoma . | NA | {
"id": "C0149925",
"name": "small cell carcinoma",
"pos": [
125,
145
]
} | {
"id": "C0007121",
"name": "bronchogenic carcinoma",
"pos": [
192,
214
]
} |
studies with specific substrates and che inhibitors indicated that most of the che of human muscle membrane and its fractions was acetylcholinesterase , and that the minor component was pseudocholinesterase . | NA | {
"id": "C0001044",
"name": "acetylcholinesterase",
"pos": [
130,
150
]
} | {
"id": "C0008429",
"name": "pseudocholinesterase",
"pos": [
186,
206
]
} |
cell suspensions of acth cell adenomas of 10 patients with nelson 's syndrome were investigated for in-vitro secretion of acth . | NA | {
"id": "C1306214",
"name": "cell",
"pos": [
0,
4
]
} | {
"id": "C0027577",
"name": "nelson 's syndrome",
"pos": [
59,
77
]
} |
table 1 lists various effects of tryptophan or 5htp that have been potentiated by fluoxetine . | NA | {
"id": "C0041249",
"name": "tryptophan",
"pos": [
33,
43
]
} | {
"id": "C0000578",
"name": "5htp",
"pos": [
47,
51
]
} |
another possible explanation might be that , unlike 5-htp research , tryptophan studies have so far disregarded the patient 's serotonergic status . | NA | {
"id": "C0000578",
"name": "5-htp",
"pos": [
52,
57
]
} | {
"id": "C0041249",
"name": "tryptophan",
"pos": [
69,
79
]
} |
immunochemical studies using a group of monoclonal human auto-antibodies ( anti-i and anti-i cold agglutinins ) and a mouse hybridoma antibody ( anti-ssea-1 ) have revealed an interrelated system of carbohydrate antigens which also involves the major blood group antigens . | NA | {
"id": "C0003250",
"name": "monoclonal",
"pos": [
40,
50
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
134,
142
]
} |
this distribution of galactocerebroside may also be true of other glycosphingolipids and , therefore , we called these glycolipids cytoskeleton-associated glycolipid ( cag ) . | NA | {
"id": "C0017978",
"name": "glycosphingolipids",
"pos": [
66,
84
]
} | {
"id": "C0017950",
"name": "cag",
"pos": [
168,
171
]
} |
these data demonstrated that myocardial membrane lipid profile was greatly altered by increased incorporation of 14c-palmitate into phospholipids and neutral lipids after endotoxin administration . | NA | {
"id": "C0025249",
"name": "membrane lipid",
"pos": [
40,
54
]
} | {
"id": "C0031676",
"name": "phospholipids",
"pos": [
132,
145
]
} |
these data demonstrated that myocardial membrane lipid profile was greatly altered by increased incorporation of 14c-palmitate into phospholipids and neutral lipids after endotoxin administration . | NA | {
"id": "C0025249",
"name": "membrane lipid",
"pos": [
40,
54
]
} | {
"id": "C0023779",
"name": "lipids",
"pos": [
158,
164
]
} |
its depletion following trauma and burn may undermine re cell and neutrophil defense against infection and bacteremia , thus contributing to organ failure during septic shock . | NA | {
"id": "C0043251",
"name": "trauma",
"pos": [
24,
30
]
} | {
"id": "C0006434",
"name": "burn",
"pos": [
35,
39
]
} |
when nephramine , a mixture rich in branched-chain amino acids , was infused , plasma alpha-amino nitrogen levels rose but urea output did not increase in either the control state or in shock , suggesting that these amino acids were not rapidly deaminated to serve as fuels . | NA | {
"id": "C0002521",
"name": "branched-chain amino acids",
"pos": [
36,
62
]
} | {
"id": "C0002520",
"name": "amino",
"pos": [
216,
221
]
} |
it is concluded that of all the amino acids tested only glycine and alanine are deaminated rapidly enough to serve as exogenous fuels in shock . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
32,
43
]
} | {
"id": "C0017890",
"name": "glycine",
"pos": [
56,
63
]
} |
it is concluded that of all the amino acids tested only glycine and alanine are deaminated rapidly enough to serve as exogenous fuels in shock . | NA | {
"id": "C0002520",
"name": "amino acids",
"pos": [
32,
43
]
} | {
"id": "C0001898",
"name": "alanine",
"pos": [
68,
75
]
} |
we have found that sodium fluoride-induced histamine release from mouse mast cells occurs in two separate steps , activation in the presence of fluoride and absence of calcium , and secretion triggered by calcium . | NA | {
"id": "C0037508",
"name": "sodium fluoride",
"pos": [
19,
34
]
} | {
"id": "C0016327",
"name": "fluoride",
"pos": [
144,
152
]
} |
we found that besides this compound a variety of hydrazones derived from other ketones and hydrazines exhibited similar or more interesting inhibition patterns both against soybean lipoxygenase and rat renal prostaglandin synthetase . | NA | {
"id": "C0020235",
"name": "hydrazones",
"pos": [
49,
59
]
} | {
"id": "C0020233",
"name": "hydrazines",
"pos": [
91,
101
]
} |
however , this and other polymorphonuclear leukocyte ( pmn ) peroxidases such as myeloperoxidase ( mpo ) would still be capable of producing destructive oxidants which contribute to inflammation . | NA | {
"id": "C0031179",
"name": "peroxidases",
"pos": [
61,
72
]
} | {
"id": "C0027021",
"name": "myeloperoxidase",
"pos": [
81,
96
]
} |
5-hydroxytryptamine amplifies the human platelet aggregation induced by threshold concentrations of adp , collagen , epinephrine , norepinephrine and induced irreversible aggregation of platelets pre-sensitized with thrombofax . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
117,
128
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
131,
145
]
} |
an analysis of virus-specific proteins of the recombinants revealed different combinations of genes coding for internal ( pl , np ) and nonstructural ( ns1 ) proteins . | NA | {
"id": "C0034861",
"name": "proteins",
"pos": [
30,
38
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
158,
166
]
} |
experimental evidence of microvascular hyperreactivity ( spasm ) , both in the hereditary cardiomyopathy of the syrian hamster and in the acquired cardiomyopathy of the hypertensive-diabetic rat , suggests that transient spasm of the myocardial microcirculation may lead to focal myocellular necrosis and scarring , whic... | NA | {
"id": "C0878544",
"name": "cardiomyopathy",
"pos": [
90,
104
]
} | {
"id": "C0853897",
"name": "cardiomyopathy",
"pos": [
147,
161
]
} |
the contraindications for the use of mcts in ketosis , acidosis , and cirrhosis are also discussed . | NA | {
"id": "C0022638",
"name": "ketosis",
"pos": [
45,
52
]
} | {
"id": "C0001122",
"name": "acidosis",
"pos": [
55,
63
]
} |
hdl cholesterol quantitation by phosphotungstate-mg2+ and by dextran sulfate-mn2+-polyethylene glycol precipitation , both with enzymic cholesterol assay compared with the lipid research method . | NA | {
"id": "C0023822",
"name": "hdl cholesterol",
"pos": [
0,
15
]
} | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
136,
147
]
} |
hdl cholesterol quantitations on 50 patient specimens by the lancer hdl cholesterol rapid stat kit ( lancer ) with phosphotungstate-mg2+ precipitation and enzymic cholesterol assay averaged 424 mg/l , and by a method with dextran sulfate-mn2+-polyethylene glycol ( dextran sulfate ) precipitation and enzymic cholesterol... | NA | {
"id": "C0023822",
"name": "hdl cholesterol",
"pos": [
0,
15
]
} | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
309,
320
]
} |
for three successive years ( 1976-1979 ) , the community surveillance system of the influenza research center identified a wave of influenza virus infections which occurred during the latter half of one epidemic period and which heralded the epidemic virus for the following year . | NA | {
"id": "C0021400",
"name": "influenza",
"pos": [
84,
93
]
} | {
"id": "C0029342",
"name": "influenza virus infections",
"pos": [
131,
157
]
} |
the body mass index was positively related to the concentration of total cholesterol and negatively related to the concentration of hdl cholesterol and the hdl cholesterol/total cholesterol ratio . | NA | {
"id": "C0023822",
"name": "hdl cholesterol",
"pos": [
132,
147
]
} | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
178,
189
]
} |
genetic study of a family with two members with weber christian disease ( panniculitis ) and alpha 1 antitrypsin deficiency . | NA | {
"id": "C0030328",
"name": "weber christian disease",
"pos": [
48,
71
]
} | {
"id": "C0030326",
"name": "panniculitis",
"pos": [
74,
86
]
} |
to determine whether peritoneal macrophages might phagocytize sperm and thereby contribute to infertility in women with endometriosis , we examined peritoneal macrophages from 32 fertile and infertile women ; | NA | {
"id": "C0021359",
"name": "infertility",
"pos": [
94,
105
]
} | {
"id": "C0021361",
"name": "infertile women",
"pos": [
191,
206
]
} |
peritoneal macrophages from infertile patients with endometriosis phagocytized more normal sperm in vitro ( 84 % +/- 4 % ) than did those from fertile women ( 43 % +/- 4 % ) or infertile women without endometriosis ( 46 % +/- 8 % ) ( p less than 0.002 ) . | NA | {
"id": "C0021359",
"name": "infertile",
"pos": [
28,
37
]
} | {
"id": "C0021361",
"name": "infertile women",
"pos": [
177,
192
]
} |
conjugated estrogens suppressed fsh in a fashion equipotent to that of the other nonsynthetic estrogens ; | NA | {
"id": "C0014938",
"name": "conjugated estrogens",
"pos": [
0,
20
]
} | {
"id": "C0014939",
"name": "estrogens",
"pos": [
94,
103
]
} |
four groups of five cycling women each received either a contraceptive vaginal ring containing a combination of either levonorgestrel or norethindrone with estradiol or oral contraceptives containing a combination of either dl-norgestrel or norethindrone with ethinyl estradiol . | NA | {
"id": "C0023566",
"name": "levonorgestrel",
"pos": [
119,
133
]
} | {
"id": "C0028368",
"name": "dl-norgestrel",
"pos": [
224,
237
]
} |
dha binding was rapid , saturable , of high affinity ( dissociation constant = 2 nm ) , and of low capacity ( 246 to 576 fmoles/mg of protein ) , and a adrenergic competitors demonstrated both stereoselectivity ( [ - ] isomer much greater than [ + ] isomer ) and a rank order of potency ( isoproterenol much greater than... | NA | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
321,
335
]
} | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
349,
360
]
} |
insulin receptors on erythrocytes were studied in nonpregnant women ( n = 14 ) during the follicular and luteal phases , and in pregnant women in the third trimester with normal body weight ( n = 14 ) , with weight gain over 14 kg during pregnancy ( n = 7 ) , and with obesity before pregnancy ( n = 7 ) . | NA | {
"id": "C0032981",
"name": "third",
"pos": [
150,
155
]
} | {
"id": "C0032961",
"name": "pregnancy",
"pos": [
284,
293
]
} |
the theoretical usefulness of volume as a predictor of fetal weight was assessed on 25 dead neonates with weight ranges between 364 and 3,650 gm . | NA | {
"id": "C0751992",
"name": "fetal weight",
"pos": [
55,
67
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
106,
112
]
} |
an experimental model of massive periretinal proliferation and intraocular neovascularization , produced in rabbits by the intravitreal injection of 250,00 cultured heterologous fibroblasts , showed no significant difference in the detachment rate ( 69 % to 100 % ) or neovascularization rate ( 45 % to 88 % ) between th... | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
178,
189
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
398,
403
]
} |
shanidar 3 experienced trauma-related degenerative joint disease at the right talocrural and talocalcaneal joints and sustained a penetrating wound across the left ninth rib . | NA | {
"id": "C0043251",
"name": "trauma",
"pos": [
23,
29
]
} | {
"id": "C0043254",
"name": "penetrating wound",
"pos": [
130,
147
]
} |
the transformed cells had a substantially higher content of putrescine and spermidine than the 3t3 cells and higher activities of all of the biosynthetic enzymes . | NA | {
"id": "C0034170",
"name": "putrescine",
"pos": [
60,
70
]
} | {
"id": "C0037871",
"name": "3t3 cells",
"pos": [
95,
104
]
} |
2 ) protein degradation rates were estimated either from the difference between the synthesis of kidney proteins and the net protein increase or by the disappearance of radioactivity from kidney proteins previously labeled by the administration of nah14co3 to mice . | NA | {
"id": "C0034861",
"name": "synthesis",
"pos": [
84,
93
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
195,
203
]
} |
second , a functional role for 17 alpha-hydroxyprogesterone ( 17ohp ) was examined as a common mediator of the inhibition of folliculogenesis by the dominant follicle and corpus luteum . | NA | {
"id": "C0045010",
"name": "17",
"pos": [
31,
33
]
} | {
"id": "C0020387",
"name": "17ohp",
"pos": [
62,
67
]
} |
progesterone replacement after clx appeared to maintain 17ohp levels , which showed a transient decrease after clx alone . | NA | {
"id": "C0033308",
"name": "progesterone",
"pos": [
0,
12
]
} | {
"id": "C0020387",
"name": "17ohp",
"pos": [
56,
61
]
} |
when the exclusion of heterologous ( human ) albumin was studied in the cat liver , much higher values were obtained than with homologous albumin . | NA | {
"id": "C0304925",
"name": "human",
"pos": [
37,
42
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
138,
145
]
} |
in addition , small arteries possess possibly more than three subtypes of alpha-adrenoceptors , including the presynaptic alpha 2-adrenoceptor . | NA | {
"id": "C0034784",
"name": "alpha-adrenoceptors",
"pos": [
74,
93
]
} | {
"id": "C0001639",
"name": "alpha 2-adrenoceptor",
"pos": [
122,
142
]
} |
because catecholamines have been reported to stimulate the sodium pump and na+-k+-atpase in skeletal and cardiac muscle , we examined the effects of isoproterenol ( 0.2-1.0 x 10 ( -6 ) m ) and norepinephrine ( 2-4 x 10 ( -7 ) m ) on intracellular sodium activity ( aina ) and twitch tension in dog purkinje strands and v... | NA | {
"id": "C0007412",
"name": "catecholamines",
"pos": [
8,
22
]
} | {
"id": "C0022245",
"name": "isoproterenol",
"pos": [
149,
162
]
} |
the diffusive in vitro uptake of homologous 125i-albumin ( ma , nmol.cm-2 ) and evans blue dye ( ebd ) ( me , nmol.cm-2 ) by the deendothelialized canine aorta from serum and from a simple albumin solution with and without ebd and with and without vigorous stirring was measured in 18 preparations . | NA | {
"id": "C0015205",
"name": "evans blue",
"pos": [
80,
90
]
} | {
"id": "C1875083",
"name": "ebd",
"pos": [
223,
226
]
} |
these observations confirm the identity of the tissue radioactivity with the labeled protein in the reagent , show that less than 10 % of the labeled protein is irreversibly bound in the tissue , indicate that significant concentration gradients do not occur in the reagent phase , and indicate that albumin appears to i... | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
85,
92
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
300,
307
]
} |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.