text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
several polar organic solvents such as ethanol and isopropanol inhibited the denitrosation and demethylation reactions and each solvent inhibited both reactions to about the same extent . | NA | {
"id": "C0001962",
"name": "ethanol",
"pos": [
39,
46
]
} | {
"id": "C0022237",
"name": "isopropanol",
"pos": [
51,
62
]
} |
under similar experimental conditions , the catalytic effects observed in vivo decreased in the same order as those observed in vitro : resorcinol greater than p-nitroso-phenol greater than catechin greater than phenol greater than or equal to guaiacol ; | NA | {
"id": "C0035197",
"name": "resorcinol",
"pos": [
136,
146
]
} | {
"id": "C0031428",
"name": "phenol",
"pos": [
212,
218
]
} |
the characteristics of non-covalent adducts obtained from the intercalative binding of 9,10,11,12-tetrahydroxytetrahydrobenzo [ e ] pyrene ( b [ e ] pt ) ( derived from the hydrolysis of b [ e ] pde ) with dna are compared to those of the covalent b [ e ] pde -- dna adducts . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
206,
209
]
} | {
"id": "C0242958",
"name": "dna adducts",
"pos": [
263,
274
]
} |
the retention of creatine phosphokinase by the digitonin-lysed cells is accounted for by complete retention of mitochondrial creatine phosphokinase and 20 % of mm-creatine phosphokinase . | NA | {
"id": "C0010287",
"name": "creatine phosphokinase",
"pos": [
17,
39
]
} | {
"id": "C0914594",
"name": "mitochondrial creatine phosphokinase",
"pos": [
111,
147
]
} |
the retention of creatine phosphokinase by the digitonin-lysed cells is accounted for by complete retention of mitochondrial creatine phosphokinase and 20 % of mm-creatine phosphokinase . | NA | {
"id": "C0010287",
"name": "creatine phosphokinase",
"pos": [
17,
39
]
} | {
"id": "C0010291",
"name": "mm-creatine phosphokinase",
"pos": [
160,
185
]
} |
at each level of potassium between 2.7 and 17 mm , acidosis induced by increasing pco2 ( respiratory acidosis ) and by decreasing hco3- ( metabolic acidosis ) decreased resting membrane potential , the maximum rate of rise of the action potential upstroke ( vmax ) , and slowed conduction . | NA | {
"id": "C0001122",
"name": "acidosis",
"pos": [
51,
59
]
} | {
"id": "C0001127",
"name": "respiratory acidosis",
"pos": [
89,
109
]
} |
furthermore , papillary plasma flow was restored to normal ( 25.3 +/- 3.9 ml/min per 100 g ) in five dogs in which furosemide was infused during angiotensin ii blockage with saralasin , despite a similar diuresis and natriuresis as the other furosemide group . | NA | {
"id": "C0003009",
"name": "angiotensin ii",
"pos": [
145,
159
]
} | {
"id": "C0036193",
"name": "saralasin",
"pos": [
174,
183
]
} |
at 3 weeks after infarction , when macrophages were the predominant infiltrating cell and there was a proliferation of blood vessels and fibroblasts , there continued to be significant increases in the production of both prostacyclin ( measured as 6-keto pgf1 alpha ) and thromboxane ( measured as txb2 ) . | NA | {
"id": "C0007634",
"name": "cell",
"pos": [
81,
85
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
137,
148
]
} |
the relative potency of beta-adrenergic agonists in producing a relaxation was isoproterenol greater than norepinephrine greater than epinephrine much greater than terbutaline . | NA | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
106,
120
]
} | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
134,
145
]
} |
in four patients , the site of epicardial breakthrough during ventricular tachycardia bore no relationship ( i.e. , greater than 3 cm away ) to the late potential or the site of origin of the tachycardia . | NA | {
"id": "C0042514",
"name": "ventricular tachycardia",
"pos": [
62,
85
]
} | {
"id": "C0039231",
"name": "tachycardia",
"pos": [
192,
203
]
} |
the interaction of sodium nitroprusside with human endothelial cells and platelets : nitroprusside and prostacyclin synergistically inhibit platelet function . | NA | {
"id": "C0037533",
"name": "sodium nitroprusside",
"pos": [
19,
39
]
} | {
"id": "C0028193",
"name": "nitroprusside",
"pos": [
85,
98
]
} |
the evidence for enzyme binding to cellular constituents , and its effects on function and properties of enzyme and isoenzymes , is reviewed . | NA | {
"id": "C0014442",
"name": "enzyme",
"pos": [
17,
23
]
} | {
"id": "C0022173",
"name": "isoenzymes",
"pos": [
116,
126
]
} |
apolipoprotein c-i , c-ii and c-iii were significantly correlated with each other , whereas neither apolipoprotein b nor apolipoprotein e was correlated with any other apolipoprotein . | NA | {
"id": "C0003593",
"name": "apolipoprotein b",
"pos": [
100,
116
]
} | {
"id": "C0003591",
"name": "apolipoprotein",
"pos": [
168,
182
]
} |
apolipoprotein c-i , c-ii and c-iii were significantly correlated with each other , whereas neither apolipoprotein b nor apolipoprotein e was correlated with any other apolipoprotein . | NA | {
"id": "C0003595",
"name": "apolipoprotein",
"pos": [
0,
14
]
} | {
"id": "C0003591",
"name": "apolipoprotein",
"pos": [
168,
182
]
} |
the steroids of the progesterone pathway ( progesterone , testosterone , androstenedione , 17-hydroxyprogesterone ) are directly quantitated by integration ( using 254 nm absorbance ) of the resultant peak areas . | NA | {
"id": "C0033308",
"name": "progesterone",
"pos": [
20,
32
]
} | {
"id": "C0020387",
"name": "17-hydroxyprogesterone",
"pos": [
91,
113
]
} |
urinary excretion of prostaglandin e2 ( pge2 ) and f2 alpha ( pgf2 alpha ) , plasma concentrations of renin ( prc ) , aldosterone ( pac ) , noradrenaline ( pna ) and adrenaline ( pa ) were determined in the third trimester of pregnancy , 5 days and 3 months after delivery in preeclampsia and normotensive pregnant and n... | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
140,
153
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
166,
176
]
} |
simultaneous measurement of the 0800-hr plasma concentrations of deoxycorticosterone ( doc ) , corticosterone ( b ) , 18-hydroxycorticosterone ( 18-ohb ) , aldosterone , 18-hydroxydeoxycorticosterone ( 18-ohdoc ) and cortisol ( f ) in four types of primary aldosteronism provides evidence for primary adrenal disease . | NA | {
"id": "C0010124",
"name": "corticosterone",
"pos": [
70,
84
]
} | {
"id": "C0000172",
"name": "18-hydroxycorticosterone",
"pos": [
118,
142
]
} |
patients with cushing 's disease or the ectopic acth-excess syndrome have normal or low production of the mchs , aldosterone and 18-hydroxycorticosterone ( 18-ohb ) , by the zona glomerulosa ( zg ) , elevated cortisol and deoxycorticosterone ( doc ) levels , and high-normal to elevated production of the mchs corticoste... | NA | {
"id": "C0000172",
"name": "18-hydroxycorticosterone",
"pos": [
129,
153
]
} | {
"id": "C0010124",
"name": "corticosterone",
"pos": [
350,
364
]
} |
concentrations in venous plasma of adrenaline , noradrenaline and dopamine were measured in samples collected simultaneously from three different sites in three varieties of hypertension . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
35,
45
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
48,
61
]
} |
plasma renin activity , angiotensin ii and free adrenaline and noradrenaline leves were highest at 0900 h in normotensives and uncomplicated hypertensives . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
48,
58
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
63,
76
]
} |
however failure of angiotensin ii , adrenaline or noradrenaline to fall at night in subjects with increased vascular reactivity could contribute to their nocturnal hypertension . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
36,
46
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
50,
63
]
} |
clonidine , noradrenaline and adrenaline , given intracisternally , differed in their effects on the magnitude and duration of the systemic component of the somatic pressor reflex . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
12,
25
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
30,
40
]
} |
a steady state model of angiotensin production and metabolism has been constructed and shows that 55 % of arterial angiotensin ii and 40 % of angiotensin iii are derived in the peripheral vascular bed . | NA | {
"id": "C0003018",
"name": "angiotensin",
"pos": [
24,
35
]
} | {
"id": "C0003009",
"name": "angiotensin ii",
"pos": [
142,
156
]
} |
a steady state model of angiotensin production and metabolism has been constructed and shows that 55 % of arterial angiotensin ii and 40 % of angiotensin iii are derived in the peripheral vascular bed . | NA | {
"id": "C0003018",
"name": "angiotensin",
"pos": [
24,
35
]
} | {
"id": "C0003012",
"name": "angiotensin iii",
"pos": [
142,
157
]
} |
when administered orally ibopamine , the diisobutyric ester of n-methyldopamine , has pharmacological properties similar to intravenous dopamine : in particular , both renal blood flow and the urinary excretion of sodium and water increase . | NA | {
"id": "C0011498",
"name": "methyldopamine",
"pos": [
65,
79
]
} | {
"id": "C0013030",
"name": "dopamine",
"pos": [
136,
144
]
} |
there was a central reticular pattern of microfilaments predominantly composed of 7-nm filaments in the fibroblasts but with a larger proportion of 10-nm filaments in the osteosarcoma cells . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
104,
115
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
184,
189
]
} |
angulation can be plastic deformation associated with delayed fracture union , and is induced by weight-bearing on fractures with cortical weakness ( comminution or deficiency ) , especially if the nail is of small diameter . | NA | {
"id": "C0016658",
"name": "fractures",
"pos": [
115,
124
]
} | {
"id": "C0476171",
"name": "comminution",
"pos": [
150,
161
]
} |
patients with doughnut scintigrams had a significantly greater incidence of severe septal hypokinesis ( p less than 0.001 ) and apical dyskinesis ( p less than 0.03 ) . | NA | {
"id": "C0086439",
"name": "hypokinesis",
"pos": [
90,
101
]
} | {
"id": "C0013384",
"name": "dyskinesis",
"pos": [
135,
145
]
} |
captopril kinetics were as previously reported in normal subjects , with the exception that time to maximum concentration ( tmax ) to free captopril was slightly higher and the half-life ( t1/2 ) was slightly shorter than in normal subjects . | NA | {
"id": "C0022702",
"name": "kinetics",
"pos": [
10,
18
]
} | {
"id": "C0018517",
"name": "half-life",
"pos": [
177,
186
]
} |
amiodarone is a benzofuran derivative with depressant effects on all electrically active cardiac tissues and important antiarrhythmic properties after long-term dosing . | NA | {
"id": "C0002598",
"name": "amiodarone",
"pos": [
0,
10
]
} | {
"id": "C0005068",
"name": "benzofuran",
"pos": [
16,
26
]
} |
for instance , in the swimbladder mucosa of the cod , noradrenaline dominates , while adrenaline is the major catecholamine in most other organs innervated by adrenergic neurons . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
54,
67
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
86,
96
]
} |
the effect of angiotensin ii ( aii ) , norepinephrine ( ne ) , epinephrine ( e ) and isoproterenol ( iso ) was observed on the branchial and systemic circulations in a whole-body-pump perfused dogfish preparation . | NA | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
39,
53
]
} | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
63,
74
]
} |
those who had previous or present atopic dermatitis had most frequently developed dermatitis during the first year of their service . | NA | {
"id": "C0011615",
"name": "atopic dermatitis",
"pos": [
34,
51
]
} | {
"id": "C0011603",
"name": "dermatitis",
"pos": [
82,
92
]
} |
reference ( normal ) ranges for alkaline phosphatase , total bilirubin , urea nitrogen , chloride , cholesterol , total carbon dioxide , creatine phosphokinase , gamma glutamyl transpeptidase , glucose , lactic dehydrogenase , aspartate and aminotransferase , alanine aminotransferase , sorbitol dehydrogenase and trigly... | NA | {
"id": "C0002594",
"name": "aminotransferase",
"pos": [
241,
257
]
} | {
"id": "C0001899",
"name": "alanine aminotransferase",
"pos": [
260,
284
]
} |
whereas the hypermetabolic response to burn injury appeared t be independent of thyroid hormones , mr was correlated positively with burn size and with elevated plasma norepinephrine and epinephrine concentrations for several weeks after injury . | NA | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
168,
182
]
} | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
187,
198
]
} |
the cell lines were exposed to various concentrations of four chemical clastogens , including the alkylating agents diepoxybutane , mitomycin c , and nitrogen mustard , as well as the antitumor glycopeptide bleomycin . | NA | {
"id": "C0017953",
"name": "glycopeptide",
"pos": [
194,
206
]
} | {
"id": "C0005740",
"name": "bleomycin",
"pos": [
207,
216
]
} |
certain restricted parts of the molecule are autoantigenic but the response to these epitopes is similar to that provoked by foreign antigens with respect to diversity of class , clonality and probably idiotypy . | NA | {
"id": "C0003316",
"name": "epitopes",
"pos": [
85,
93
]
} | {
"id": "C0003320",
"name": "antigens",
"pos": [
133,
141
]
} |
two types of receptor may be responsible for the actions of substance p on peripheral tissues : the sp-p type , where all tachykinins are approximately equally active , and the sp-e type , where eledoisin and kassinin are more potent than the other tachykinins . | NA | {
"id": "C0038585",
"name": "substance p",
"pos": [
60,
71
]
} | {
"id": "C0039241",
"name": "tachykinins",
"pos": [
249,
260
]
} |
two types of receptor may be responsible for the actions of substance p on peripheral tissues : the sp-p type , where all tachykinins are approximately equally active , and the sp-e type , where eledoisin and kassinin are more potent than the other tachykinins . | NA | {
"id": "C0022528",
"name": "kassinin",
"pos": [
209,
217
]
} | {
"id": "C0039241",
"name": "tachykinins",
"pos": [
249,
260
]
} |
the mean dna content per cell and heterogeneity of cell populations with respect to dna content were measured in samples of peripheral blood mononuclear cells from donors of different ages . | NA | {
"id": "C0007634",
"name": "cell",
"pos": [
25,
29
]
} | {
"id": "C1321301",
"name": "peripheral blood mononuclear cells",
"pos": [
124,
158
]
} |
to determine the change in nuclear protein content as a function of cell cycle position , isolated hela nuclei were stained for protein with fluorescein isothiocyanate ( fitc ) and for dna with propidium iodide ( pi ) and analyzed by flow cytometry ( fcm ) . | NA | {
"id": "C0028589",
"name": "nuclear protein",
"pos": [
27,
42
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
128,
135
]
} |
the cause of altered reactivity of transformed cells with this fluorescent probe has been investigated by a detailed analysis of its reaction with chicken embryo fibroblasts transformed by a temperature sensitive mutant of rous sarcoma virus . | NA | {
"id": "C0007634",
"name": "cells",
"pos": [
47,
52
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
162,
173
]
} |
the metabolism and excretion of the hepatocarcinogen 2,6-dinitro-toluene ( 2,6-dnt ) was investigated in fischer-344 rats in vivo and in isolated perfused livers . | NA | {
"id": "C0025519",
"name": "metabolism",
"pos": [
4,
14
]
} | {
"id": "C0221102",
"name": "excretion",
"pos": [
19,
28
]
} |
administration ( po ) of the unsaturated nitriles acrylonitrile , crotonitrile , and 3-butenenitrile yielded 37 % , 5.6 % , and 29 % of the dose as scn- , whereas after ip injection 4.5 % , 4.6 % , and 18 % of the doses were excreted as scn- , respectively . | NA | {
"id": "C0028131",
"name": "nitriles",
"pos": [
41,
49
]
} | {
"id": "C0001223",
"name": "acrylonitrile",
"pos": [
50,
63
]
} |
the plasma clearance , tissue distribution , metabolism , and excretion of free adriamycin ( adr ) and liposome-entrapped adr ( adr/l ) was examined after iv and ip administration to rats . | NA | {
"id": "C0025519",
"name": "metabolism",
"pos": [
45,
55
]
} | {
"id": "C0221102",
"name": "excretion",
"pos": [
62,
71
]
} |
after administration of glucose there was a definite rise in blood-glucose , serum-insulin and c-peptide concentrations . | NA | {
"id": "C0017725",
"name": "glucose",
"pos": [
24,
31
]
} | {
"id": "C0005802",
"name": "in",
"pos": [
88,
90
]
} |
nonetheless , palatinite appears to be suitable as a sugar substitute in a diabetic diet , since in comparison with glucose there are no significant changes in blood-sugar levels and no additional insulin consumption is induced . | NA | {
"id": "C0017725",
"name": "glucose",
"pos": [
116,
123
]
} | {
"id": "C0005802",
"name": "in blood-sugar",
"pos": [
157,
171
]
} |
cyclosporin a is a cyclical polypeptide of 11 amino acids , one of which is unique to the cyclosporins . | NA | {
"id": "C0010592",
"name": "cyclosporin a",
"pos": [
0,
13
]
} | {
"id": "C0010594",
"name": "cyclosporins",
"pos": [
90,
102
]
} |
precursor cells , labelled initially with 3h-thymidine , were transformed after 5 days into early neuroblasts , these cells in turn giving rise to neurons some 8 days later . | NA | {
"id": "C0018956",
"name": "precursor cells",
"pos": [
0,
15
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
118,
123
]
} |
studies on the metabolism of steroid hormones revealed that prl decreased lh-stimulated androsterone and 5 alpha-androstane-3 alpha , 17 beta-diol accumulation by 99 % , androstenedione by 94 % , testosterone by 90 % , dehydroepiandrosterone by more than 80 % , pregnenolone and 17 alpha-hydroxyprogesterone by 80 % , 17... | NA | {
"id": "C0373704",
"name": "pregnenolone",
"pos": [
262,
274
]
} | {
"id": "C0376260",
"name": "17 alpha-hydroxypregnenolone",
"pos": [
318,
346
]
} |
however , nephrectomized pigs had no detectable increase in plasma 25-hydroxyvitamin d3 ( 25ohd3 ) -26,23-lactone concentrations throughout the experiment , in contrast with the high plasma concentrations of 25ohd3-26,23-lactone in the control pigs . | NA | {
"id": "C0006657",
"name": "25-hydroxyvitamin d3",
"pos": [
67,
87
]
} | {
"id": "C2713074",
"name": "25ohd3",
"pos": [
208,
214
]
} |
in contrast , in vivo chlorpropamide did not alter gtp , guanylylimidodiphosphate , or fluoride-stimulated adenylate cyclase activities in these renal membranes . | NA | {
"id": "C0018353",
"name": "gtp",
"pos": [
51,
54
]
} | {
"id": "C0018366",
"name": "guanylylimidodiphosphate",
"pos": [
57,
81
]
} |
the expression of the proopiomelanocortin ( pomc ) gene by normal lung and thyroid was examined by measurement of the content of acth , beta-lipotropin ( beta lph ) , and beta-endorphin ( beta ep ) in porcine lung and thyroid tissue . | NA | {
"id": "C0033195",
"name": "proopiomelanocortin",
"pos": [
22,
41
]
} | {
"id": "C0023832",
"name": "beta-lipotropin",
"pos": [
136,
151
]
} |
the content of ir-beta lph in both tissues exceeded by severalfold , on a molar basis , the content of ir-acth and ir-beta ep , suggesting that the common precursor pomc was processed predominantly to peptides other than ir-acth and ir-beta ep . | NA | {
"id": "C0023832",
"name": "beta lph",
"pos": [
18,
26
]
} | {
"id": "C0033195",
"name": "pomc",
"pos": [
165,
169
]
} |
rat myometrial tissue and endometrial cells were incubated with labeled 25-hydroxyvitamin d3 ( [ 3h-26,27 ] 25ohd3 ) for 70 min at 37 c , and the resulting metabolites were isolated by sequential sephadex lh-20 chromatography and high performance liquid chromatography . | NA | {
"id": "C0006657",
"name": "25-hydroxyvitamin d3",
"pos": [
72,
92
]
} | {
"id": "C2713074",
"name": "25ohd3",
"pos": [
108,
114
]
} |
[ ectopia cordis cranialis with anomalies of the heart-procimal vascular truncs in a calf ( short communication ) ] . | NA | {
"id": "C0013580",
"name": "ectopia cordis",
"pos": [
2,
16
]
} | {
"id": "C0018798",
"name": "anomalies of the heart",
"pos": [
32,
54
]
} |
comparison of the effects of antibody fragments directed against immunoglobulin or lymphocyte antigens on acute secondary disease . | NA | {
"id": "C0021009",
"name": "antibody fragments",
"pos": [
29,
47
]
} | {
"id": "C0021027",
"name": "immunoglobulin",
"pos": [
65,
79
]
} |
hybrids of aprt-deficient mouse cells and of human fibroblasts having normal aprt were isolated by fusing the parental cells with sendai virus , blocking de novo purine nucleotide synthesis with azaserine and selecting for hybrids that could use exogenous adenine . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
51,
62
]
} | {
"id": "C0007634",
"name": "the",
"pos": [
183,
186
]
} |
patients with symptomatic gastrooesophageal reflux tended to have abnormal acid clearance , as did those with oesophageal motility disorders . | NA | {
"id": "C0017168",
"name": "gastrooesophageal reflux",
"pos": [
26,
50
]
} | {
"id": "C0014858",
"name": "oesophageal motility disorders",
"pos": [
110,
140
]
} |
six patients with hyperphagia ( ingestion of 5-11 000 kcals/day ) associated with severe malabsorption and steatorrhoea are described . | NA | {
"id": "C0024523",
"name": "malabsorption",
"pos": [
89,
102
]
} | {
"id": "C0038238",
"name": "steatorrhoea",
"pos": [
107,
119
]
} |
[ differential diagnosis of chronic obstructive pulmonary disease -- with special respect to roentgen diagnosis of pulmonary emphysema ( author 's transl ) ] . | NA | {
"id": "C0024117",
"name": "chronic obstructive pulmonary disease",
"pos": [
28,
65
]
} | {
"id": "C0034067",
"name": "pulmonary emphysema",
"pos": [
115,
134
]
} |
for the first time , an o-antigenic lipopolysaccharide ( lps ) has been isolated from a filamentous blue-green alga ( anabaena variabilis ) . | NA | {
"id": "C0069180",
"name": "o-antigenic",
"pos": [
24,
35
]
} | {
"id": "C0023810",
"name": "lipopolysaccharide",
"pos": [
36,
54
]
} |
the polysaccharide moiety of this lps consists of l-rhamnose , its 3-o-methyl ether l-acofriose , d-mannose , d-glucose , and d-galactose . l-glycero-d-mannoheptose and 2-keto-3-deoxyoctonate , the two characteristic sugar components of enteric lps , and phosphate groups are absent from the a. variabilis o antigen . | NA | {
"id": "C0023810",
"name": "lps",
"pos": [
34,
37
]
} | {
"id": "C0069180",
"name": "o antigen",
"pos": [
306,
315
]
} |
the lps of a. variabilis is localized in the outermost cell wall layer and behaves like a bacterial o antigen in serological tests . | NA | {
"id": "C0023810",
"name": "lps",
"pos": [
4,
7
]
} | {
"id": "C0069180",
"name": "bacterial o antigen",
"pos": [
90,
109
]
} |
ribonucleic acid-deoxyribonucleic acid ( rna-dna ) hybridization was employed for the determination of messenger rna transcribed from the ilv gene cluster of escherichia coli k-12 . | NA | {
"id": "C0035668",
"name": "ribonucleic acid",
"pos": [
0,
16
]
} | {
"id": "C0035696",
"name": "messenger rna",
"pos": [
103,
116
]
} |
we conclude that the two lytic activities may be associated with a single protein or a lytic enzyme complex composed of two enzymes . | NA | {
"id": "C0026741",
"name": "enzyme complex",
"pos": [
93,
107
]
} | {
"id": "C0014442",
"name": "enzymes",
"pos": [
124,
131
]
} |
the majority of the ribonucleic acid made in a 10-min period during sporulation does not migrate on gels with precursor or mature ribosomal ribonucleic acid . | NA | {
"id": "C0035668",
"name": "ribonucleic acid",
"pos": [
20,
36
]
} | {
"id": "C0035701",
"name": "ribosomal ribonucleic acid",
"pos": [
130,
156
]
} |
separation of amino sugar- and hexose-containing tryptic peptides by gel filtration indicated that all of the nonlipid carbohydrate of the cell envelope is covalently bound to protein . | NA | {
"id": "C0002531",
"name": "amino sugar",
"pos": [
14,
25
]
} | {
"id": "C0007004",
"name": "carbohydrate",
"pos": [
119,
131
]
} |
the efflux of rb ( + ) from preloaded islets followed exponential kinetics with a half-life of about 16 min . | NA | {
"id": "C0022702",
"name": "kinetics",
"pos": [
66,
74
]
} | {
"id": "C0018517",
"name": "half-life",
"pos": [
82,
91
]
} |
marked presynaptic supersensitivity to adrenaline and noradrenaline was observed in left atria and inferior venae cavae following treatment with 6-hydroxydopamine . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
39,
49
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
54,
67
]
} |
[ pathogenetic classification of growth disorders caused by infectious and parasitic diseases . study of the laws regulating their relationships ] . | NA | {
"id": "C0009450",
"name": "infectious",
"pos": [
60,
70
]
} | {
"id": "C0030499",
"name": "parasitic diseases",
"pos": [
75,
93
]
} |
the ribosomal proteins were analyzed by two-dimensional polyacrylamide gel electrophoresis : the proteins extracted with acetic acid were the most soluble in the sample gel solution ; | NA | {
"id": "C0035552",
"name": "ribosomal proteins",
"pos": [
4,
22
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
97,
105
]
} |
comparison between the action of gtp and 5'-guanylyl-imidodiphosphate on the particulate enzyme from bovine adrenal cortex and rat adrenals . | NA | {
"id": "C0018353",
"name": "gtp",
"pos": [
33,
36
]
} | {
"id": "C0018366",
"name": "guanylyl-imidodiphosphate",
"pos": [
44,
69
]
} |
effect of chloride and benzoate anions on the delayed light emission in dcmu-treated spinach chloroplasts . | NA | {
"id": "C0008203",
"name": "chloride",
"pos": [
10,
18
]
} | {
"id": "C0003075",
"name": "anions",
"pos": [
32,
38
]
} |
[ concentrations of cholesterol and cholesterol esters in the liver of mice infested with schistosoma mansoni ] . | NA | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
20,
31
]
} | {
"id": "C0008387",
"name": "cholesterol esters",
"pos": [
36,
54
]
} |
the effect of abnormal human hemoglobin ( hbs ) on the blood meal size of the hematophagous bug rhodnius prolixus . | NA | {
"id": "C0019047",
"name": "abnormal",
"pos": [
14,
22
]
} | {
"id": "C0019043",
"name": "hbs",
"pos": [
42,
45
]
} |
although differences in body weight between the homozygous di and heterozygous normal rats accounted for differences in the weights of the heart and gonads , the weights of the spleen , liver and kidney were not solely body-weight dependent ; | NA | {
"id": "C0005911",
"name": "differences",
"pos": [
9,
20
]
} | {
"id": "C0005910",
"name": "body-weight",
"pos": [
219,
230
]
} |
[ study on the stechiometry of a ternary complex formed from basic proteins , phospholipids and mitochondrial proteins ] . | NA | {
"id": "C0033684",
"name": "proteins",
"pos": [
67,
75
]
} | {
"id": "C0949610",
"name": "mitochondrial proteins",
"pos": [
96,
118
]
} |
carbonated bupivacaine , plain bupivacaine hydrochloride , and bupivacaine hydrochloride with adrenaline were used to provide epidural analgesia for patients undergoing vaginal hysterectomy . | NA | {
"id": "C0006400",
"name": "bupivacaine",
"pos": [
11,
22
]
} | {
"id": "C0887621",
"name": "bupivacaine hydrochloride",
"pos": [
63,
88
]
} |
the lipid fraction in the perfusate from the heart was isolated and analysed for prostaglandins by thin layer chromatography and quantitative assay on the rat isolated stomach strip.2 infusion of acetylcholine at a rate of 8 mug/min significantly increased the outflow of prostaglandins from the heart , from 1.8 to 6.2 ... | NA | {
"id": "C0033559",
"name": "prostaglandin e",
"pos": [
713,
728
]
} | {
"id": "C0033554",
"name": "prostaglandins",
"pos": [
816,
830
]
} |
maximal contractile effects of angiotensin ii , oxytocin and prostaglandin f ( 2alpha ) were thus observed when the ratio oestrogen/progesterone levels was high.2 the oestrogen-dependent sensitivity of the rat uterus is partially mediated by endogenous prostaglandins . | NA | {
"id": "C0033561",
"name": "prostaglandin f",
"pos": [
61,
76
]
} | {
"id": "C0033554",
"name": "prostaglandins",
"pos": [
253,
267
]
} |
in the metoestrus uterus , prostaglandin f ( 2alpha ) induced the reappearance of spontaneous contractions.4 prostaglandin f ( 2alpha ) had a potentiating effect on angiotensin-elicited contractions which persisted after washing out prostaglandin f ( 2alpha ) . | NA | {
"id": "C0033554",
"name": "prostaglandin",
"pos": [
27,
40
]
} | {
"id": "C0033561",
"name": "prostaglandin f",
"pos": [
233,
248
]
} |
the ventricular ectopic beats were late , and depending upon the refractory period of the a-v node these extrasystoles were interpolated or followed by compensatory pauses . | NA | {
"id": "C0151636",
"name": "ventricular ectopic beats",
"pos": [
4,
29
]
} | {
"id": "C0340464",
"name": "extrasystoles",
"pos": [
105,
118
]
} |
the elements most likely to be meaningful in relation to such discrimination are molybdenum , magnesium , copper , lead , phosphorus , strontium , and possibly zirconium and potassium . | NA | {
"id": "C0013879",
"name": "elements",
"pos": [
4,
12
]
} | {
"id": "C0031705",
"name": "phosphorus",
"pos": [
122,
132
]
} |
the concentrations of magnesium and phosphorus were significantly correlated with a number of other elements in the samples . | NA | {
"id": "C0031705",
"name": "phosphorus",
"pos": [
36,
46
]
} | {
"id": "C0013879",
"name": "elements",
"pos": [
100,
108
]
} |
the list of disorders that accompany cryoglobulinaemia includes multiple myeloma , waldenstrom 's disease , idiopathic glomerulonephritis , and , in particular , autoimmune diseases , such as the sjogren syndrome and disseminated lupus erythematosus . | NA | {
"id": "C0004364",
"name": "autoimmune diseases",
"pos": [
162,
181
]
} | {
"id": "C0024141",
"name": "disseminated lupus erythematosus",
"pos": [
217,
249
]
} |
action of porcine proinsulin and insulin on gastric acid secretion and blood sugar in conscious dogs . | NA | {
"id": "C0033362",
"name": "proinsulin",
"pos": [
18,
28
]
} | {
"id": "C0021641",
"name": "insulin",
"pos": [
33,
40
]
} |
therefore , sub-intimal fibrous hyperplasia , responsible for the structure changes of the grafts , does not seem to be a slowly evolutive pathologic process but seems rather to stabilize itself after one year . | NA | {
"id": "C0020507",
"name": "hyperplasia",
"pos": [
32,
43
]
} | {
"id": "C0030660",
"name": "pathologic process",
"pos": [
139,
157
]
} |
using hvh 2 antisera of rabbit ( titre 1:256 , dilution 1:10 ) , antologous serum of cervix carcinoma patients ( dilution 1:1 to 1:5 ) and allogenic serum of cervix carcinoma patients without hvh 2 antibodies ( dilution 1:1 to 1:5 ) , tumour material obtained from various cancerization stages of cervix carcinoma in 50 ... | NA | {
"id": "C0020960",
"name": "antisera",
"pos": [
12,
20
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
198,
208
]
} |
gastro-intestinal hormones and bile secretion in the perfused pig liver : the effects of secretin , cholecystokinin and pentagastrin . | NA | {
"id": "C0017182",
"name": "gastro-intestinal hormones",
"pos": [
0,
26
]
} | {
"id": "C0036534",
"name": "secretin",
"pos": [
89,
97
]
} |
gastro-intestinal hormones and bile secretion in the perfused pig liver : the effects of secretin , cholecystokinin and pentagastrin . | NA | {
"id": "C0017182",
"name": "gastro-intestinal hormones",
"pos": [
0,
26
]
} | {
"id": "C0008328",
"name": "cholecystokinin",
"pos": [
100,
115
]
} |
proceedings : a micromethod for the assay of purine phosphoribosyltransferases in cultured human fibroblasts and amniotic cells . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
97,
108
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
122,
127
]
} |
the normal cells were the l929 fibroblasts and epithelial-like cells from bone marrow and corneal tissue . | NA | {
"id": "C0007634",
"name": "normal cells",
"pos": [
4,
16
]
} | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
31,
42
]
} |
[ effectiveness of health-resort-climate therapy of patients with coronary artery arteriosclerosis under the conditions of the northern zone of the black sea coast in the caucasus ] . | NA | {
"id": "C1956346",
"name": "coronary artery",
"pos": [
66,
81
]
} | {
"id": "C0003850",
"name": "arteriosclerosis",
"pos": [
82,
98
]
} |
this assay could measure metronidazole in the presence of gentamicin or in the presence of penicillin , with the use of penicillinase incorporated into the assay plates , or in presence of penicillin , methicillin , and cephalothin with prior exposure of the specimen to beta-lactamase . | NA | {
"id": "C0030841",
"name": "penicillinase",
"pos": [
120,
133
]
} | {
"id": "C0597979",
"name": "beta-lactamase",
"pos": [
271,
285
]
} |
this assay could measure metronidazole in the presence of gentamicin or in the presence of penicillin , with the use of penicillinase incorporated into the assay plates , or in presence of penicillin , methicillin , and cephalothin with prior exposure of the specimen to beta-lactamase . | NA | {
"id": "C0030842",
"name": "penicillin",
"pos": [
91,
101
]
} | {
"id": "C0025643",
"name": "methicillin",
"pos": [
202,
213
]
} |
each chain was found to contain 15-18 % glycine and significant amounts of the amino acids hydroxyproline and hydroxylysine . | NA | {
"id": "C0017890",
"name": "glycine",
"pos": [
40,
47
]
} | {
"id": "C0002520",
"name": "amino acids",
"pos": [
79,
90
]
} |
nh ( 2 ) oh , i ( 2 ) and naio ( 4 ) reacted with all the four thionucleosides of e. coli trna , 4-thiouridine ( s ( 4 ) u ) , 5-methylaminomethyl-2-thiouridine ( mnm ( 5 ) s ( 2 ) u ) , 2-thiocytidine ( s ( 2 ) c ) and 2-methylthio-n ( 6 ) -isopentenyladenosine ( ms ( 2 ) i ( 6 ) a ) , to various extents . | NA | {
"id": "C0039922",
"name": "thionucleosides",
"pos": [
63,
78
]
} | {
"id": "C0039959",
"name": "4-thiouridine",
"pos": [
97,
110
]
} |
desulphurization of e. coli trna with cnbr resulted in marked loss of acceptor activities for glutamic acid , glutamine and lysine . | NA | {
"id": "C0061472",
"name": "glutamic acid",
"pos": [
94,
107
]
} | {
"id": "C0017797",
"name": "glutamine",
"pos": [
110,
119
]
} |
copolymeric oligosaccharides obtained after alkaline elimination were cleaved by chondroitinase-ac into disaccharide and higher oligosaccharides . | NA | {
"id": "C0012611",
"name": "disaccharide",
"pos": [
104,
116
]
} | {
"id": "C0028959",
"name": "oligosaccharides",
"pos": [
128,
144
]
} |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.