text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
neurological complications included chorea , currently of a minor degree , replaced by buccofacial dyskinesias and compulsive movements . | NA | {
"id": "C0008489",
"name": "chorea",
"pos": [
36,
42
]
} | {
"id": "C0013384",
"name": "dyskinesias",
"pos": [
99,
110
]
} |
in the field of motor control , its hypoactivity appears to determine not only chorea but dyskinesias similar to tics and compulsive movements . | NA | {
"id": "C0086439",
"name": "hypoactivity",
"pos": [
36,
48
]
} | {
"id": "C0013384",
"name": "dyskinesias",
"pos": [
90,
101
]
} |
in the field of motor control , its hypoactivity appears to determine not only chorea but dyskinesias similar to tics and compulsive movements . | NA | {
"id": "C0008489",
"name": "chorea",
"pos": [
79,
85
]
} | {
"id": "C0013384",
"name": "dyskinesias",
"pos": [
90,
101
]
} |
the role , if any , of these enzymes in promoting infection by pathogenic members of the genera neisseria , hemophilus , and streptococcus is not known , although the secretory immune system is primarily mediated by antibodies of the iga isotype , among which are iga1 subclass proteins , and these proteins are suscepti... | NA | {
"id": "C0020835",
"name": "antibodies",
"pos": [
216,
226
]
} | {
"id": "C0021017",
"name": "isotype",
"pos": [
238,
245
]
} |
thus , the transport of radiolabeled proteins in the axon reflects the movement of complete subcellular rather than the movement of individual proteins . | NA | {
"id": "C0007292",
"name": "transport",
"pos": [
11,
20
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
143,
151
]
} |
to our knowledge , this is the first description of a rheumatoid factor , which is classified as an autoimmune antibody , acting in a protective manner . | NA | {
"id": "C0035448",
"name": "rheumatoid factor",
"pos": [
54,
71
]
} | {
"id": "C0004358",
"name": "autoimmune antibody",
"pos": [
100,
119
]
} |
pulmonary hypertension could be attributed to underlying lung disease in three and was considered to be primary in the remaining patient . | NA | {
"id": "C0020542",
"name": "pulmonary",
"pos": [
0,
9
]
} | {
"id": "C0024115",
"name": "lung disease",
"pos": [
57,
69
]
} |
although patients with rheumatoid arthritis also may have vasculitis , neurological complications are usually related to nerve compression by rheumatoid nodules or the arthritic process itself . | NA | {
"id": "C0003873",
"name": "rheumatoid arthritis",
"pos": [
23,
43
]
} | {
"id": "C0035450",
"name": "rheumatoid nodules",
"pos": [
142,
160
]
} |
cholecystokinin ( cck ) and its c-terminal octapeptide analog , sincalide , have been utilized in two separate roles for the evaluation of gallbladder disease . | NA | {
"id": "C0008328",
"name": "cholecystokinin",
"pos": [
0,
15
]
} | {
"id": "C0037167",
"name": "sincalide",
"pos": [
64,
73
]
} |
it appears reasonable that cck or sincalide cholecystography or cholescintigraphy may be detecting functional abnormalities before anatomic changes occur and can , therefore , serve as a useful examination in selecting symptomatic patients who may benefit from cholecystectomy . | NA | {
"id": "C0008328",
"name": "cck",
"pos": [
27,
30
]
} | {
"id": "C0037167",
"name": "sincalide",
"pos": [
34,
43
]
} |
since all biopsy-negative patients who responded to treatment normally reserved for reflux esophagitis had a positive t-n/10 hcl test , it is possible that this test was able to detect early incipient esophagitis , before histologic changes became apparent at biopsy . | NA | {
"id": "C0014869",
"name": "reflux esophagitis",
"pos": [
84,
102
]
} | {
"id": "C0014868",
"name": "esophagitis",
"pos": [
201,
212
]
} |
cimetidine has been shown to inhibit the liver microsomal metabolism of the benzodiazepines diazepam and chlordiazepoxide , resulting in an increase in half-life and decrease in the clearance of these two drugs . | NA | {
"id": "C0005064",
"name": "benzodiazepines",
"pos": [
76,
91
]
} | {
"id": "C0008188",
"name": "chlordiazepoxide",
"pos": [
105,
121
]
} |
thus , when clinically indicated , oxazepam and lorazepam may be the benzodiazepines of choice to use in combination with cimetidine to eliminate the clinically significant drug interaction seen with diazepam and chlordiazepoxide . | NA | {
"id": "C0005064",
"name": "benzodiazepines",
"pos": [
69,
84
]
} | {
"id": "C0008188",
"name": "chlordiazepoxide",
"pos": [
213,
229
]
} |
is it cost effective to treat people with asymptomatic stones when one half of gallstones detected at autopsy have not caused trouble in life ? | NA | {
"id": "C0006736",
"name": "stones",
"pos": [
55,
61
]
} | {
"id": "C0008350",
"name": "gallstones",
"pos": [
79,
89
]
} |
treatment of hemobilia is primarily surgical , with direct exploration of the liver , ligation of the bleeding point , and relief of bile duct obstruction . | NA | {
"id": "C0018994",
"name": "hemobilia",
"pos": [
13,
22
]
} | {
"id": "C0019080",
"name": "bleeding",
"pos": [
102,
110
]
} |
based upon experiments on animals , an anastomotic apparatus , consisting of two magnetic rings of polymer bonded , rare earth cobalt magnets embedded in polyester , was developed . | NA | {
"id": "C0032521",
"name": "polymer",
"pos": [
99,
106
]
} | {
"id": "C0032474",
"name": "polyester",
"pos": [
154,
163
]
} |
a retrospective study of the computerized tomographic ( ct ) examinations of 20 children and 13 adults with craniopharyngiomas was undertaken , with special attention paid to the densitometric characteristics of the tumors ( contrast enhancement and presence of cysts and calcifications ) . | NA | {
"id": "C0027651",
"name": "tumors",
"pos": [
216,
222
]
} | {
"id": "C0010709",
"name": "cysts",
"pos": [
262,
267
]
} |
the cause of the hemorrhage was found when a trigeminal neurinoma with an old intracapsular hematoma was exposed . | NA | {
"id": "C0019080",
"name": "hemorrhage",
"pos": [
17,
27
]
} | {
"id": "C0018944",
"name": "hematoma",
"pos": [
92,
100
]
} |
indications for delayed operative intervention were hepatic abscess with sepsis ( four patients ) and expanding hematoma and blood loss ( two patients ) . | NA | {
"id": "C0018944",
"name": "hematoma",
"pos": [
112,
120
]
} | {
"id": "C0019080",
"name": "blood loss",
"pos": [
125,
135
]
} |
two patients are described in whom the characteristic dermatitis , glucose intolerance , weight loss , and anemia of the glucagonoma syndrome were due to a metastasizing islet cell carcinoma . | NA | {
"id": "C0017689",
"name": "glucagonoma syndrome",
"pos": [
121,
141
]
} | {
"id": "C1328479",
"name": "islet cell carcinoma",
"pos": [
170,
190
]
} |
neuroleptics will get their best use in confused or delirious states : their main side effects are of extrapyramidal nature . | NA | {
"id": "C0009676",
"name": "confused",
"pos": [
40,
48
]
} | {
"id": "C0011206",
"name": "delirious",
"pos": [
52,
61
]
} |
the efficacy of ketotifen , a tricyclic benzocycloheptathiophene derivative , was assessed in an outpatient clinical trial and in a group of 12 asthmatic subjects with exercise-induced asthma . | NA | {
"id": "C0004096",
"name": "asthmatic",
"pos": [
144,
153
]
} | {
"id": "C0004099",
"name": "exercise-induced asthma",
"pos": [
168,
191
]
} |
this receptor was discriminatory in that heat denatured dsdna , poly a , poly c , poly c x i and poly c x poly i failed to substantially inhibit either the platelet binding of , or platelet aggregation induced by , dsdna ; | NA | {
"id": "C0032408",
"name": "poly c",
"pos": [
73,
79
]
} | {
"id": "C0032414",
"name": "poly c",
"pos": [
97,
103
]
} |
the results support the view that viiir : ag , which binds heterologous antibodies , is non-covalently linked to a smaller subunit , viii : c , which binds homologous antibodies . | NA | {
"id": "C0003248",
"name": "heterologous antibodies",
"pos": [
59,
82
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
167,
177
]
} |
in native plasma , or after mixing with factor viii concentrate , antibodies of the second group did not form immune complexes with the whole factor viii molecular complex . | NA | {
"id": "C0003241",
"name": "antibodies",
"pos": [
66,
76
]
} | {
"id": "C0003313",
"name": "immune complexes",
"pos": [
110,
126
]
} |
the effect of a 45-week treatment with different doses of 2,3,7,8-tetrachloro-dibenzo-p-dioxin ( tcdd ) ( 0.01 , 0.10 and 1.00 microgram/kg/week ) was evaluated in female rat liver by determining cytochrome p-450 and b5 content and the activities of the enzymes cytochrome c reductase , aryl hydrocarbon hydroxylase ( ah... | NA | {
"id": "C0010762",
"name": "cytochrome",
"pos": [
196,
206
]
} | {
"id": "C0003927",
"name": "aryl hydrocarbon hydroxylase",
"pos": [
287,
315
]
} |
the effect of a 45-week treatment with different doses of 2,3,7,8-tetrachloro-dibenzo-p-dioxin ( tcdd ) ( 0.01 , 0.10 and 1.00 microgram/kg/week ) was evaluated in female rat liver by determining cytochrome p-450 and b5 content and the activities of the enzymes cytochrome c reductase , aryl hydrocarbon hydroxylase ( ah... | NA | {
"id": "C0003927",
"name": "aryl hydrocarbon hydroxylase",
"pos": [
287,
315
]
} | {
"id": "C0000644",
"name": "7-ethoxycoumarin o-deethylase",
"pos": [
328,
357
]
} |
cytochrome b5 and cytochrome c reductase were unaffected at any of the dose levels and cytochrome p-450 was significantly induced only at the highest tcdd dose , but marked induction of ahh and 7-ecd was apparent when the animals were treated with 0.01 microgram/kg/week ; | NA | {
"id": "C0010762",
"name": "cytochrome p-450",
"pos": [
87,
103
]
} | {
"id": "C0003927",
"name": "ahh",
"pos": [
186,
189
]
} |
the paper deals with the content of free and esterified cholesterol and also with the activity of cholesterol acetyltransferase and cholesterol esterase in the fraction of plasma membranes and liver subcellular fractions of rabbits fed a ration supplemented with cholesterol and sunflower oil . | NA | {
"id": "C0008387",
"name": "esterified cholesterol",
"pos": [
45,
67
]
} | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
263,
274
]
} |
norepinephrine , epinephrine and phenylephrine dose dependently increased the basal tone and the frequency of spontaneous contractions and decreased their amplitudes , which were depressed by phentolamine . | NA | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
0,
14
]
} | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
17,
28
]
} |
previous studies have shown that local instillation of the mucopolysaccharide heparin can prevent bacterial adsorption on the bladder mucosa denuded of this `` '' antiadherence factor . '' '' | NA | {
"id": "C0017973",
"name": "mucopolysaccharide",
"pos": [
59,
77
]
} | {
"id": "C0019134",
"name": "heparin",
"pos": [
78,
85
]
} |
to determine whether this action was due to the mucopolysaccharide composition of heparin , or rather to its anticoagulant property , protamine sulfate ( a basic protein with anticoagulant properties ) was tested for antiadsorptive efficacy . | NA | {
"id": "C0017973",
"name": "mucopolysaccharide",
"pos": [
48,
66
]
} | {
"id": "C0019134",
"name": "heparin",
"pos": [
82,
89
]
} |
residues of chlorinated hydrocarbons were detected in all examined samples , the hexachlorobenzene concentration was explicitly higher than the concentrations of ddt and lindane . | NA | {
"id": "C0020247",
"name": "chlorinated hydrocarbons",
"pos": [
12,
36
]
} | {
"id": "C0005038",
"name": "lindane",
"pos": [
170,
177
]
} |
t-2 toxin ( 3-hydroxy-4,15-diacetoxy-8- [ 3-methyl-butyrloxy ] -12,13-epoxy-delta 9-trichothecene ) and diacetoxyscirpenol , structurally similar trichothecene mycotoxins , in dimethylsulfoxide : saline ( 1:9 v/v ) solvent , were given by crop gavage to 7-day-old male broiler chickens . | NA | {
"id": "C0039185",
"name": "t-2 toxin",
"pos": [
0,
9
]
} | {
"id": "C0040952",
"name": "trichothecene",
"pos": [
146,
159
]
} |
we also counted the relative number of mast cells in the tissue ( normalized to 5,000 fibroblast-like and mesothelial-like cells ) , since this might influence 48/80-induced mast-cell-mediated proliferation . | NA | {
"id": "C0016030",
"name": "fibroblast",
"pos": [
86,
96
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
123,
128
]
} |
in order to explain this regional aortic susceptibility to atherosclerosis , cholesterol and cholesteryl ester concentrations and prostaglandin biosynthesis in the two aortic regions were examined . | NA | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
77,
88
]
} | {
"id": "C0008387",
"name": "cholesteryl ester",
"pos": [
93,
110
]
} |
the analyses of the labeled proline and , especially , hydroxyproline revealed that synthesis and degradation are reduced in senescent rats . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
28,
35
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
55,
69
]
} |
the metabolic activity was measured in vivo by following the incorporation of 3h-proline into hydroxyproline over the course of 3 months . | NA | {
"id": "C0033382",
"name": "proline",
"pos": [
81,
88
]
} | {
"id": "C0020388",
"name": "hydroxyproline",
"pos": [
94,
108
]
} |
low molecular weight dextran ( rheomacrodex ) was infused into dextran resistant rats in a dose of 5 g/kg body weight . | NA | {
"id": "C0011793",
"name": "low molecular weight dextran",
"pos": [
0,
28
]
} | {
"id": "C0086140",
"name": "dextran",
"pos": [
63,
70
]
} |
the modified protein corresponded immunochemically to the human blood serum albumin , did not contain polymers , had a decreased amount of alpha-helix structures as shown by dispersion of optic rotation and its molecular mass was similar to the mass of native albumin . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
13,
20
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
260,
267
]
} |
the modified protein corresponded immunochemically to the human blood serum albumin , did not contain polymers , had a decreased amount of alpha-helix structures as shown by dispersion of optic rotation and its molecular mass was similar to the mass of native albumin . | NA | {
"id": "C0304925",
"name": "human blood serum albumin",
"pos": [
58,
83
]
} | {
"id": "C0001924",
"name": "albumin",
"pos": [
260,
267
]
} |
nuclease activity was studied using as a substrate native rna as well as synthetic polyribonucleotides polyu and polyu-polya in blood serum of healthy persons and of patients with leukoses and myelofibrosis . | NA | {
"id": "C0032590",
"name": "polyribonucleotides",
"pos": [
83,
102
]
} | {
"id": "C0032400",
"name": "polya",
"pos": [
119,
124
]
} |
[ effect of amantadine ( 1-aminoadamantane ) and remantadine ( alpha-methyl-1-adamantane methyl amine ) hydrochlorides on formation of influenza a viral proteins ] . | NA | {
"id": "C0002403",
"name": "1-aminoadamantane",
"pos": [
25,
42
]
} | {
"id": "C0001392",
"name": "adamantane",
"pos": [
78,
88
]
} |
[ effect of amantadine ( 1-aminoadamantane ) and remantadine ( alpha-methyl-1-adamantane methyl amine ) hydrochlorides on formation of influenza a viral proteins ] . | NA | {
"id": "C0035629",
"name": "remantadine",
"pos": [
49,
60
]
} | {
"id": "C0001392",
"name": "adamantane",
"pos": [
78,
88
]
} |
inhibitory effect of amantadine ( i-amino adamantane ) and remantadine ( alpha-methyl-1-adamantane methylamine ) hydrochlorides on reproduction of influenza a virus as well as , in particular , on formation of virus specific proteins was studied in cell culture . | NA | {
"id": "C0002403",
"name": "amantadine",
"pos": [
21,
31
]
} | {
"id": "C0001392",
"name": "adamantane",
"pos": [
88,
98
]
} |
inhibitory effect of amantadine ( i-amino adamantane ) and remantadine ( alpha-methyl-1-adamantane methylamine ) hydrochlorides on reproduction of influenza a virus as well as , in particular , on formation of virus specific proteins was studied in cell culture . | NA | {
"id": "C0035629",
"name": "remantadine",
"pos": [
59,
70
]
} | {
"id": "C0001392",
"name": "adamantane",
"pos": [
88,
98
]
} |
patterns of lipid and lipoprotein turnover were examined in blood and aorta of 6-10 months old and 4-4.5 years old rabbits with the renal form of experimental hypertension , experimental atherosclerosis and combination of both pathological states . | NA | {
"id": "C0023779",
"name": "lipid",
"pos": [
12,
17
]
} | {
"id": "C0023820",
"name": "lipoprotein",
"pos": [
22,
33
]
} |
the extracted pulmonary lipids were separated by thin-layer chromatography into 5 fractions ( phospholipids , cholesterol , fatty acids , triglycerides , cholesterol esters ) and evaluated densitometrically . | NA | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
110,
121
]
} | {
"id": "C0008387",
"name": "cholesterol esters",
"pos": [
154,
172
]
} |
a number of examples demonstrate the effectiveness of rational strategies of strain development , e. g. , the removal of non-specific repressions of secondary metabolism by environmental factors , the excessive production of precursors due to altered control of intermediary metabolism , the increased resistance of prod... | NA | {
"id": "C0025519",
"name": "intermediary metabolism",
"pos": [
262,
285
]
} | {
"id": "C0221102",
"name": "elimination",
"pos": [
548,
559
]
} |
consecutive injuries of thoracic traumata are : haemato - and/or pneumothorax 35 % , lung contusion 20 % , heart concussion/contusion 15 % , rupture of diaphragm 4 % , aortic disruption 2 % , bronchus rupture 1 % . | NA | {
"id": "C0039980",
"name": "injuries",
"pos": [
12,
20
]
} | {
"id": "C0043251",
"name": "traumata",
"pos": [
33,
41
]
} |
[ diagnostic delay of abdominal injuries due to alcoholic intoxication . subtotal rupture of the stomach from the duodenum ] . | NA | {
"id": "C0848377",
"name": "abdominal injuries",
"pos": [
22,
40
]
} | {
"id": "C0038357",
"name": "rupture of",
"pos": [
82,
92
]
} |
the 40s ribosomal protein , s9 , analogous to mammalian s6 protein , was phosphorylated in vivo but was not phosphorylated in vitro by either of the cyclic amp-independent protein kinases . | NA | {
"id": "C0035552",
"name": "ribosomal protein",
"pos": [
8,
25
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
172,
179
]
} |
the obtained results clearly indicate that cyclic amp-independent yeast protein kinases might be involved in the modification in vivo of some ribosomal proteins , in particular of the strongly acidic proteins of 60s ribosome subunit . | NA | {
"id": "C0035552",
"name": "ribosomal proteins",
"pos": [
142,
160
]
} | {
"id": "C0033684",
"name": "proteins",
"pos": [
200,
208
]
} |
all of these babies had a neural tube closure defect ( five anencephaly and three anencephaly with spina bifida ) . | NA | {
"id": "C0027794",
"name": "neural tube",
"pos": [
26,
37
]
} | {
"id": "C0002902",
"name": "anencephaly",
"pos": [
82,
93
]
} |
the concentration of estradiol-17 beta in cyst fluid may be helpful in distinguishing follicle cysts from neoplastic cysts . | NA | {
"id": "C0016427",
"name": "follicle cysts",
"pos": [
86,
100
]
} | {
"id": "C0010709",
"name": "cysts",
"pos": [
117,
122
]
} |
different effects of oestradiol , oestriol , oestetrol and of oestrone on human breast cancer cells ( mcf-7 ) in long term tissue culture . | NA | {
"id": "C0014927",
"name": "oestriol",
"pos": [
34,
42
]
} | {
"id": "C0014899",
"name": "oestetrol",
"pos": [
45,
54
]
} |
the effects of oestradiol ( oe2 ) , oestrone ( oe1 ) , oestriol ( oe3 ) , oestetrol ( oe4 ) on the induction of the progesterone receptor ( pgr ) and growth of mcf-7 cells are compared . | NA | {
"id": "C0014927",
"name": "oestriol",
"pos": [
55,
63
]
} | {
"id": "C0014899",
"name": "oestetrol",
"pos": [
74,
83
]
} |
[ effect of muscular exercise and metabolic control on cortisol , growth hormone , plasma-epinephrine and plasma-norepinephrine in type-i diabetics [ author 's transl ) ] . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
90,
101
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
113,
127
]
} |
in the present study we investigated the influence of muscular exercise on stress-hormones ( cortisol , growth hormone , epinephrine , norepinephrine ) in nonketotic , juvenile-type diabetics ( jd ) in relation to the degree of metabolic control . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
121,
132
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
135,
149
]
} |
the exercise induced rise in cortisol , epinephrine and norepinephrine wa similar in both groups of diabetics and not significantly different compared with controls . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
40,
51
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
56,
70
]
} |
the results demonstrate that muscular exercise shows a similar effect on cortisol , epinephrine and norepinephrine , but not on growth hormone concentrations in nonketotic , conventionally treated jd compared with controls . | NA | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
84,
95
]
} | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
100,
114
]
} |
the unselective pde inhibitors theophylline ( 2.5 mm ) and ibmx ( 0.2 mm ) and the selective cyclic gmp pde inhibitor m & b 22948 ( 0.1 mm ) inhibited the antigen induced histamine release by 50 % while 48/80 induced release was inhibited by about 25 % . | NA | {
"id": "C0039771",
"name": "theophylline",
"pos": [
31,
43
]
} | {
"id": "C0000096",
"name": "ibmx",
"pos": [
59,
63
]
} |
dna replication of simian virus 40 nucleoprotein complexes ( sv40 chromatin ) in saponin-treated permeable cells was found to be more efficient than that in digitonin-treated permeable cells . | NA | {
"id": "C0028612",
"name": "nucleoprotein",
"pos": [
35,
48
]
} | {
"id": "C0008546",
"name": "chromatin",
"pos": [
66,
75
]
} |
the molecular weight of the viral dna was very similar to that of sv40 dna and the dna cleavage patterns obtained after digestion with hind ii and hind iii restriction endonucleases were indistinguishable from those of sv40 . | NA | {
"id": "C0012939",
"name": "viral dna",
"pos": [
28,
37
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
83,
86
]
} |
protein content of the purified virus fractions was up to 4 microgram/ml , of which virus protein represented up to 5 % . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
0,
7
]
} | {
"id": "C0042736",
"name": "virus protein",
"pos": [
84,
97
]
} |
free lipid a from phase i and phase ii coxiella burnetii lipopolysaccharides was isolated and studied serologically . | NA | {
"id": "C0023767",
"name": "lipid a",
"pos": [
5,
12
]
} | {
"id": "C0023810",
"name": "lipopolysaccharides",
"pos": [
57,
76
]
} |
arrhythmogenic right ventricular dysplasia ( arvd ) , a cardiomyopathy with hypokinetic ares limited to the wall of the right ventricle ( rv ) , has been recently described as a cause of recurrent ventricular tachycardia ( vt ) in young adults with an otherwise normal heart . | NA | {
"id": "C0349788",
"name": "arrhythmogenic right ventricular dysplasia",
"pos": [
0,
42
]
} | {
"id": "C0878544",
"name": "cardiomyopathy",
"pos": [
56,
70
]
} |
in the other parameters , including cholesterol and high-density lipoprotein cholesterol , no decrease or increase was observed . | NA | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
36,
47
]
} | {
"id": "C0023822",
"name": "high-density lipoprotein cholesterol",
"pos": [
52,
88
]
} |
at entry into the program there was a significant correlation between hdl-c and several indices of overweight -- relative weight , body mass index and sum of skinfold thickness . | NA | {
"id": "C0497406",
"name": "overweight",
"pos": [
99,
109
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
122,
128
]
} |
proteins from grains and vegetables were identical in both menus and contributed about 35 % of dietary protein . | NA | {
"id": "C3486457",
"name": "proteins",
"pos": [
0,
8
]
} | {
"id": "C0012177",
"name": "dietary protein",
"pos": [
95,
110
]
} |
although plasma high-density lipoprotein cholesterol decreased slightly , the high-density lipoprotein cholesterol to cholesterol ratio ( high-density lipoprotein cholesterol/total cholesterol ) remained constant for most individuals . | NA | {
"id": "C0023822",
"name": "high-density lipoprotein cholesterol",
"pos": [
16,
52
]
} | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
181,
192
]
} |
preterm infants ( 35.5 +/- 0.4 wk ) with body weight appropriate for gestational age had lower values of bfm and sum of st as compared to the control group , without differences in fcw ( 0.23 +/- 0.03 versus 0.22 +/- 0.02 micrograms ) . | NA | {
"id": "C0005910",
"name": "body weight",
"pos": [
41,
52
]
} | {
"id": "C0005911",
"name": "differences",
"pos": [
166,
177
]
} |
in infants born between 30 and 41 wk of gestation with body weights at birth appropriate for gestational age , st and bfm progressively increase with gestational age , while the fcw remains constant . | NA | {
"id": "C0005612",
"name": "body weights",
"pos": [
55,
67
]
} | {
"id": "C0005910",
"name": "fcw",
"pos": [
178,
181
]
} |
in full-term newborns with different body weight at birth , fat cell weight was correlated to bfm ( r = 0.67 ; p less than 0.01 ) , to bfm as percentage of body weight ( r = 0.67 ; p less than 0.001 ) and to st ( r = 0.73 ; p less than 0.001 ) . | NA | {
"id": "C0005911",
"name": "different body weight",
"pos": [
27,
48
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
161,
167
]
} |
guaran , tragacanth , gum arabic , carrageenan , gum karaya , and methylcellulose were used in a long-term feeding study to evaluate their effects upon adaptive responses of nutritionally controlled parameters in rats by feeding a fiber-free diet containing increasing additions of polysaccharides . | NA | {
"id": "C0007289",
"name": "carrageenan",
"pos": [
35,
46
]
} | {
"id": "C0032594",
"name": "polysaccharides",
"pos": [
282,
297
]
} |
apparent digestibilities of hemicellulose , cellulose , and lignin in the high fiber diet were 88 , 42 , and 18 % , respectively . | NA | {
"id": "C0007648",
"name": "cellulose",
"pos": [
32,
41
]
} | {
"id": "C0023705",
"name": "lignin",
"pos": [
60,
66
]
} |
we studied intestinal mucosal disaccharidase ( lactase , sucrase , and maltase ) specific activity in suckling ( 1 and 2 wk old ) , weanling ( 3 wk old ) , and postweaning ( 4 and 6 wk old ) control and growth-retarded ( malnourished ) rats . | NA | {
"id": "C0012610",
"name": "disaccharidase",
"pos": [
30,
44
]
} | {
"id": "C0038634",
"name": "sucrase",
"pos": [
57,
64
]
} |
the effect of penicillins ( ampicillin , carbenicillin , penicillin g , and penicilloic acid ) and aminoglycosides ( amikacin , gentamicin , streptomycin , and tobramycin ) on the accuracy of clinitest , diastix , and testape determinations of glycosuria was studied . | NA | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
28,
38
]
} | {
"id": "C0030827",
"name": "penicillin g",
"pos": [
57,
69
]
} |
the effect of penicillins ( ampicillin , carbenicillin , penicillin g , and penicilloic acid ) and aminoglycosides ( amikacin , gentamicin , streptomycin , and tobramycin ) on the accuracy of clinitest , diastix , and testape determinations of glycosuria was studied . | NA | {
"id": "C0006976",
"name": "carbenicillin",
"pos": [
41,
54
]
} | {
"id": "C0030827",
"name": "penicillin g",
"pos": [
57,
69
]
} |
the effect of penicillins ( ampicillin , carbenicillin , penicillin g , and penicilloic acid ) and aminoglycosides ( amikacin , gentamicin , streptomycin , and tobramycin ) on the accuracy of clinitest , diastix , and testape determinations of glycosuria was studied . | NA | {
"id": "C0002556",
"name": "aminoglycosides",
"pos": [
99,
114
]
} | {
"id": "C0017436",
"name": "gentamicin",
"pos": [
128,
138
]
} |
the effect of penicillins ( ampicillin , carbenicillin , penicillin g , and penicilloic acid ) and aminoglycosides ( amikacin , gentamicin , streptomycin , and tobramycin ) on the accuracy of clinitest , diastix , and testape determinations of glycosuria was studied . | NA | {
"id": "C0002556",
"name": "aminoglycosides",
"pos": [
99,
114
]
} | {
"id": "C0038425",
"name": "streptomycin",
"pos": [
141,
153
]
} |
measurement of deoxycorticosterone and corticosterone ( and in some patient of 18-hydroxydeoxycorticosterone and 18-hydroxycorticosterone ) was not significantly higher than normal . | NA | {
"id": "C0010124",
"name": "corticosterone",
"pos": [
20,
34
]
} | {
"id": "C0000172",
"name": "18-hydroxycorticosterone",
"pos": [
113,
137
]
} |
recommended treatment for suspected peritonitis in patients with shunts is systemic antimicrobial therapy with an agent active against staphylococci plus an aminoglycoside , followed by removal of the shunt if the diagnosis is confirmed . | NA | {
"id": "C1136254",
"name": "antimicrobial",
"pos": [
84,
97
]
} | {
"id": "C0002556",
"name": "aminoglycoside",
"pos": [
157,
171
]
} |
this study of 17 patients with vasculitic neuropathy ( polyarteritis nodosa in 11 , rheumatoid arthritis in five , and systemic lupus erythematosus in one ) revealed the following : ( 1 ) polyneuropathy is the most common manifestation of peripheral neuropathy in polyarteritis nodosa . | NA | {
"id": "C0152025",
"name": "polyneuropathy",
"pos": [
188,
202
]
} | {
"id": "C0031117",
"name": "peripheral neuropathy",
"pos": [
239,
260
]
} |
other features included initial hyponatremia and the combination of hypoproteinemia , hypoalbuminemia , hypocalcemia and hypophosphatemia of several days ' duration . | NA | {
"id": "C0020639",
"name": "hypoproteinemia",
"pos": [
68,
83
]
} | {
"id": "C0239981",
"name": "hypoalbuminemia",
"pos": [
86,
101
]
} |
isosorbide dinitrate increased the cardiac output during exercise from 4.6 +/- 0.9 liter/min to 5.3 +/- 0.8 liter/min ( p less than 0.01 ) but also did not change exercise vo2 ( control , 488 +/- 62 ml/min ; isosorbide , 473 +/- 44 ml/min ) , peak lactate concentration ( control , 19.2 +/- 6.0 mg/dl ; isosorbide , 21.4... | NA | {
"id": "C0022252",
"name": "isosorbide dinitrate",
"pos": [
0,
20
]
} | {
"id": "C0022251",
"name": "isosorbide",
"pos": [
381,
391
]
} |
tissue levels of catecholamines , norepinephrine ( ne ) , epinephrine ( e ) , and dopamine ( da ) were measured using a sensitive radioenzymatic assay . | NA | {
"id": "C0028351",
"name": "norepinephrine",
"pos": [
34,
48
]
} | {
"id": "C0014563",
"name": "epinephrine",
"pos": [
58,
69
]
} |
at readily attainable serum concentrations , mezlocillin inhibited significantly more isolates than cefoxitin ( p less than 0.0005 ) , ampicillin ( p less than 0.0005 ) , penicillin g ( p less than 0.005 ) , and clindamycin ( p less than 0.025 ) ; | NA | {
"id": "C0025893",
"name": "mezlocillin",
"pos": [
45,
56
]
} | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
135,
145
]
} |
at readily attainable serum concentrations , mezlocillin inhibited significantly more isolates than cefoxitin ( p less than 0.0005 ) , ampicillin ( p less than 0.0005 ) , penicillin g ( p less than 0.005 ) , and clindamycin ( p less than 0.025 ) ; | NA | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
135,
145
]
} | {
"id": "C0030827",
"name": "penicillin g",
"pos": [
171,
183
]
} |
mezlocillin was significantly more active than ampicillin ( p less than 0.025 ) , penicillin g ( p less than 0.025 ) , and clindamycin ( p less than 0.05 ) against bacteroides species other than b. fragilis and b. melaninogenicus . | NA | {
"id": "C0025893",
"name": "mezlocillin",
"pos": [
0,
11
]
} | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
47,
57
]
} |
mezlocillin was significantly more active than ampicillin ( p less than 0.025 ) , penicillin g ( p less than 0.025 ) , and clindamycin ( p less than 0.05 ) against bacteroides species other than b. fragilis and b. melaninogenicus . | NA | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
47,
57
]
} | {
"id": "C0030827",
"name": "penicillin g",
"pos": [
82,
94
]
} |
seventy patients with postpartum endomyometritis were treated with either intravenous mezlocillin ( 16 gm/day ) or ampicillin ( 8 gm/day ) in a prospective , randomized , double-blind comparison . | NA | {
"id": "C0025893",
"name": "mezlocillin",
"pos": [
86,
97
]
} | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
115,
125
]
} |
thirty of 33 mezlocillin-treated patients ( 91 % ) and 30 of 37 ampicillin-treated patients ( 81 % ) responded to initial therapy ( p greater than 0.4 ) . | NA | {
"id": "C0025893",
"name": "mezlocillin",
"pos": [
13,
24
]
} | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
64,
74
]
} |
we conclude that mezlocillin and ampicillin are equally effective and safe for therapy of postpartum endomyometritis . | NA | {
"id": "C0025893",
"name": "mezlocillin",
"pos": [
17,
28
]
} | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
33,
43
]
} |
that mezlocillin was not superior to ampicillin , despite expanded activity against b. fragilis and members of enterobacteriaceae , suggests that these pathogens are less important than was previously considered in postpartum endomyometritis . | NA | {
"id": "C0025893",
"name": "mezlocillin",
"pos": [
5,
16
]
} | {
"id": "C0002680",
"name": "ampicillin",
"pos": [
37,
47
]
} |
in the chromatogram , fraction 2 ( f2 ) including four pregnane steroids ( 17-hydroxypregnanolone , pregnanolone , pregnanediol , and pregnanetriol ) reflected the biologic activity of molar human chorionic gonadotropin ( hcg ) , and the ratio of f2 to fraction 1 ( f1 ) ( 17-ketosteroids ) was found useful in monitorin... | NA | {
"id": "C0033006",
"name": "pregnane",
"pos": [
55,
63
]
} | {
"id": "C0038317",
"name": "steroids",
"pos": [
280,
288
]
} |
in the chromatogram , fraction 2 ( f2 ) including four pregnane steroids ( 17-hydroxypregnanolone , pregnanolone , pregnanediol , and pregnanetriol ) reflected the biologic activity of molar human chorionic gonadotropin ( hcg ) , and the ratio of f2 to fraction 1 ( f1 ) ( 17-ketosteroids ) was found useful in monitorin... | NA | {
"id": "C0033006",
"name": "pregnane",
"pos": [
55,
63
]
} | {
"id": "C0033008",
"name": "pregnanolone",
"pos": [
100,
112
]
} |
a systematic study of amniotic fluid phospholipids including phosphatidylcholine ( pc , lecithin ) , saturated phosphatidylcholine , and phosphatidylglycerol was undertaken to evaluate the stability of these surfactant indices as a function of temperature and time . | NA | {
"id": "C0031617",
"name": "lecithin",
"pos": [
88,
96
]
} | {
"id": "C1959616",
"name": "phosphatidylcholine",
"pos": [
111,
130
]
} |
the prostaglandin metabolites in myometrium did not fluctuate during the cycle , but their respective ratios with the parent prostaglandins showed changes indicative of increased biosynthesis and/or reduced catabolism of pgf and reduced biosynthesis and/or increased catabolism of pge during the late secretory phase . | NA | {
"id": "C0033554",
"name": "prostaglandin",
"pos": [
4,
17
]
} | {
"id": "C0033559",
"name": "pge",
"pos": [
281,
284
]
} |
this paper describes the basic features of an ongoing double masked , randomized , controlled clinical trial which studies the changes in corneal and visual function that result when contact lenses are fitted in a manner designed to alter myopic refractive error . | NA | {
"id": "C0027092",
"name": "myopic",
"pos": [
239,
245
]
} | {
"id": "C0034951",
"name": "refractive error",
"pos": [
246,
262
]
} |
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