text
stringlengths
57
1.72k
relation
stringclasses
125 values
h
dict
t
dict
we conclude that although statistically different , both proximal and distal estimates of petco2 provide acceptable estimates of paco2 in healthy infants and children who are ventilated with a sechrist infant ventilator and an ayre 's t-piece system .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 158, 166 ] }
{ "id": "C0021270", "name": "infant", "pos": [ 202, 208 ] }
this finding should help resolve difficulties in fragile x cytogenetics where expression of the common fragile site can lead to false positive diagnoses .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 5, 12 ] }
{ "id": "C0011900", "name": "diagnoses", "pos": [ 143, 152 ] }
thus , individuals with a history of mi , stroke , transient ischemic attack , or unstable angina clearly benefit from aspirin .
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 42, 48 ] }
{ "id": "C0007787", "name": "transient", "pos": [ 51, 60 ] }
univariate and multivariate analysis with logistic regression did not show relationships between exercise-related cardiac arrhythmias and the severity of pulmonary disease , oxyhemoglobin desaturation or ecg evidence of chronic lung disease .
nichd_parent_of
{ "id": "C0024115", "name": "pulmonary disease", "pos": [ 154, 171 ] }
{ "id": "C0746102", "name": "chronic lung disease", "pos": [ 220, 240 ] }
thrombolytic therapy has been shown to limit infarct size , improve ventricular function , and decrease mortality in suspected evolving myocardial infarction ( mi ) .
nichd_parent_of
{ "id": "C0021308", "name": "infarct", "pos": [ 45, 52 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 136, 157 ] }
histologically , the cyst was an ordinary dermoid cyst , and the solid mass consisted of osteosarcoma with focal chondroblastic differentiation .
nichd_parent_of
{ "id": "C0010709", "name": "cyst", "pos": [ 21, 25 ] }
{ "id": "C0011649", "name": "dermoid cyst", "pos": [ 42, 54 ] }
use of recombinant human granulocyte macrophage colony-stimulating factor to speed engraftment and treat graft failure following marrow transplantation in man .
nichd_parent_of
{ "id": "C0087111", "name": "treat", "pos": [ 99, 104 ] }
{ "id": "C0005961", "name": "marrow transplantation", "pos": [ 129, 151 ] }
in the analyses we utilized age- and sex-corrected cranial measures ( head length , head breadth , bizygomatic diameter , minimum frontal diameter , and head circumference ) available for 526 adults ( ages 15-54 years ) .
nichd_parent_of
{ "id": "C1444754", "name": "length", "pos": [ 75, 81 ] }
{ "id": "C0262499", "name": "head", "pos": [ 153, 157 ] }
prophylactic brain irradiation has been found to decrease the risk of cerebral metastases to 4-6 % in patients affected by limited disease and complete tumor remission under chemotherapy , and to improve the quality of life without , however , showing the benefit on survival time .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 131, 138 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 152, 157 ] }
results of the study confirm the hypotheses that ( 1 ) much patient aggression within defined clinical contexts conforms to patterns of prediction directly related to person and environmental variables , and ( 2 ) the primary value of counteraggression strategies such as seclusion and restraint resides in the acute management of aggressive children and not in long-term therapeutic functions .
nichd_parent_of
{ "id": "C0027361", "name": "person", "pos": [ 167, 173 ] }
{ "id": "C0008059", "name": "children", "pos": [ 342, 350 ] }
two cases of electroconvulsive therapy ( ect ) in adolescence are presented and the literature on the use of ect in childhood and adolescence is reviewed .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 116, 125 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 130, 141 ] }
among the anxiety disorders , perhaps the most compelling evidence implicating 5-ht exists for obsessive compulsive disorder ( ocd ) .
nichd_parent_of
{ "id": "C0003469", "name": "anxiety disorders", "pos": [ 10, 27 ] }
{ "id": "C0028768", "name": "obsessive compulsive disorder", "pos": [ 95, 124 ] }
although selective angiography was necessary to detect the shape and precise location of the aneurysm , non-invasive diagnostic techniques including ultrasonography and computed tomography were also useful in detecting the aneurysm and planning the management of this unusual condition .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic", "pos": [ 117, 127 ] }
{ "id": "C0041618", "name": "ultrasonography", "pos": [ 149, 164 ] }
these viruses proved to be a closely reacting group distinct from all other rotavirus serotypes , justifying the establishment of serotype 10 as the second major type of bovine rotavirus .
nichd_parent_of
{ "id": "C0042776", "name": "viruses", "pos": [ 6, 13 ] }
{ "id": "C0035870", "name": "rotavirus", "pos": [ 177, 186 ] }
all the same , there are more troubles as far as sleep is concerned with ivf children and with the group of infertile mothers and these symptoms seem to be linked to difficulty in the mother-infant relationship .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 77, 85 ] }
{ "id": "C0021270", "name": "infant", "pos": [ 191, 197 ] }
only in a few cases ultrasound guided punctures of the cysts could be carried out and that only in ovarian cysts with clear fluid in women of reproductive age .
nichd_parent_of
{ "id": "C0010709", "name": "cysts", "pos": [ 55, 60 ] }
{ "id": "C0029927", "name": "ovarian cysts", "pos": [ 99, 112 ] }
the primary lesions were urothelial tract cancer ( 19 patients ) , malignant lymphoma ( 1 patient ) , renal cell adenocarcinoma , penile cancer , prostatic adenocarcinoma , and leiomyosarcoma ( 2 patients each ) .
nichd_parent_of
{ "id": "C0006826", "name": "cancer", "pos": [ 42, 48 ] }
{ "id": "C0024299", "name": "malignant lymphoma", "pos": [ 67, 85 ] }
the primary lesions were urothelial tract cancer ( 19 patients ) , malignant lymphoma ( 1 patient ) , renal cell adenocarcinoma , penile cancer , prostatic adenocarcinoma , and leiomyosarcoma ( 2 patients each ) .
nichd_parent_of
{ "id": "C0006826", "name": "cancer", "pos": [ 42, 48 ] }
{ "id": "C0007134", "name": "renal cell", "pos": [ 102, 112 ] }
the initial computerized tomography ( ct ) scan demonstrated a small hematoma underlying a depressed skull fracture in one patient and a small interhemispheric subdural hematoma in the other .
nichd_parent_of
{ "id": "C0018944", "name": "hematoma", "pos": [ 69, 77 ] }
{ "id": "C0018946", "name": "subdural hematoma", "pos": [ 160, 177 ] }
in this communication , the method is successfully employed in two children , an infant in whom cirrhosis developed who eventually died from acquired immunodeficiency syndrome , and one whose portal hypertension was relieved after orthotopic liver transplantation .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 67, 75 ] }
{ "id": "C0021270", "name": "infant", "pos": [ 81, 87 ] }
likewise , pregnancy outcome for this group was remarkable for an increased risk of meconium staining , cesarean delivery for fetal distress and depressed one-minute apgar scores .
nichd_parent_of
{ "id": "C0032972", "name": "pregnancy outcome", "pos": [ 11, 28 ] }
{ "id": "C0007876", "name": "cesarean", "pos": [ 104, 112 ] }
injuries consisted of thromboembolic complications leading to distal ischemia ( 46 % ) , vessel lacerations ( 26 % ) , pseudoaneurysms ( 25 % ) , and arteriovenous fistulas ( 3 % ) .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 0, 8 ] }
{ "id": "C0043246", "name": "lacerations", "pos": [ 96, 107 ] }
we report usefulness of ultrafast ct ( ufct ) in evaluation of aortic dissection , according to the results of examination of 51 patients .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 49, 59 ] }
{ "id": "C0031809", "name": "of examination", "pos": [ 108, 122 ] }
although local control of the tumor was successful in all the cases , one patient with prostatic cancer and three with bladder cancer died of cancer .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 30, 35 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 142, 148 ] }
cesium-induced arrhythmias were suppressed by the calcium antagonist diltiazem , magnesium chloride , beta blockade ( with atenolol ) , or vagal nerve stimulation -- all interventions that can suppress calcium entry . beta-adrenergic stimulation with isoproterenol initiated ventricular arrhythmias in the presence of subarrhythmic doses of cesium .
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmias", "pos": [ 15, 26 ] }
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 275, 298 ] }
the correlation of the serological results with clinical information on each child suggests that detection of iga hiv antibodies is an effective method for early diagnosis of hiv-infected infants without signs of infection .
nichd_parent_of
{ "id": "C0008059", "name": "child", "pos": [ 77, 82 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 188, 195 ] }
use of 1,25 ( oh ) 2d3 ( calcitriol ) can be of benefit in the treatment of two hereditary types of rickets and osteomalacia , vitamin d dependency type i ( vdd1 ) and x-linked hypophosphatemic vitamin d-resistant rickets ( hpdr ) .
nichd_parent_of
{ "id": "C0035579", "name": "rickets", "pos": [ 100, 107 ] }
{ "id": "C0733682", "name": "hpdr", "pos": [ 224, 228 ] }
while over 90 % of pancreatic cancer patients had elevated levels of serum span-1 antigen , only 0-17 % of patients with other malignant and non malignant gastrointestinal diseases such as pancreatitis ( chronic or acute ) , gastric cancer or colon cancer had above normal levels .
nichd_parent_of
{ "id": "C0017178", "name": "gastrointestinal", "pos": [ 155, 171 ] }
{ "id": "C0030305", "name": "pancreatitis", "pos": [ 189, 201 ] }
we compared the results of this procedure with results obtained by two other procedures ( approach to steady-state labeling and inhibition of transcription with thiolutin ) and also evaluated whether heat shock alter mrna decay rates .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 77, 87 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 182, 191 ] }
evidence is drawn from both clinical observations and experimental studies in a spectrum of movement disorders ranging from ballism through chorea to parkinsonism .
nichd_parent_of
{ "id": "C0026650", "name": "movement disorders", "pos": [ 92, 110 ] }
{ "id": "C0008489", "name": "chorea", "pos": [ 140, 146 ] }
to investigate the role of complement in crohn 's disease we measured jejunal-fluid concentrations of the complement components c4 , c3 , and factor b by perfusion of a closed segment of the jejunum in 22 patients with crohn 's disease thought to be limited to the terminal ileum .
nichd_parent_of
{ "id": "C0005889", "name": "fluid", "pos": [ 78, 83 ] }
{ "id": "C0009516", "name": "complement components c4", "pos": [ 106, 130 ] }
the american nurses ' association 's council of clinical nurse specialists and council of primary health care nurse practitioners conducted a survey of all graduate nursing programs in the united states that prepare nurse practitioners and/or clinical nurse specialists .
nichd_parent_of
{ "id": "C0004927", "name": "conducted", "pos": [ 130, 139 ] }
{ "id": "C0006147", "name": "nursing", "pos": [ 165, 172 ] }
a taxonomy of infants ' behavioral states is described , composed of ten primary states : alert , nonalert waking , fuss , cry , drowse , daze , sleep-wake transition , active sleep , active-quiet transition , and quiet sleep .
nichd_parent_of
{ "id": "C0004927", "name": "behavioral", "pos": [ 24, 34 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 220, 225 ] }
this technically simpler procedure is effective for treating genuine stress urinary incontinence in women who also require surgical repair of other pelvic-floor defects .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 25, 34 ] }
{ "id": "C0543467", "name": "surgical", "pos": [ 123, 131 ] }
when the number of fetuses in multifetal pregnancies is reduced in the first trimester , the gender and karyotypic status of individual fetuses are rarely , if ever known .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 125, 135 ] }
{ "id": "C0015965", "name": "fetuses", "pos": [ 136, 143 ] }
in a double-blind study of 40 healthy adult patients undergoing a variety of minor oral surgical procedures , the anesthetic techniques were assessed with respect to the following parameters : patients ' subjective evaluation of the anesthesia , the level of response to injection of local anesthetic , psychomotor ability after surgery , recovery times , and the frequency of adverse effects .
nichd_parent_of
{ "id": "C0002903", "name": "anesthesia", "pos": [ 233, 243 ] }
{ "id": "C0002921", "name": "local anesthetic", "pos": [ 284, 300 ] }
the appearance of thrombotic microangiopathy ( thrombotic thrombocytopenic purpura , haemolytic uraemic syndrome ) could have been documented in a 23 years old pregnant woman , who had been treated previously for immune-thrombocytolytic purpura .
nichd_parent_of
{ "id": "C2717961", "name": "thrombotic microangiopathy", "pos": [ 18, 44 ] }
{ "id": "C0034155", "name": "thrombotic thrombocytopenic", "pos": [ 47, 74 ] }
in the 40th week a healthy newborn was delivered by cesarean section and after delivery congenital heart disease , rhythm disorder , infection or metabolic disturbance could n't be verified .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 122, 130 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 133, 142 ] }
our investigation also failed to demonstrate any electrically detectable muscle activity in muscles where the patients during the examination reported pain ( paraspinal , trapezius and tibial anterior muscles ) .
nichd_parent_of
{ "id": "C0220825", "name": "investigation", "pos": [ 4, 17 ] }
{ "id": "C0031809", "name": "patients", "pos": [ 110, 118 ] }
to test whether these observations are reproducible in the differential diagnosis of soft tissue sarcomas , anti-hla-dr antibodies lk8d3 and ln3 were applied to formalin-fixed , paraffin-embedded sections of mfh , neurofibrosarcoma ( nfs ) , leiomyosarcoma ( lms ) , synovial sarcoma ( ss ) , fibrosarcoma ( fs ) , angiosarcoma ( as ) , kaposi 's sarcoma ( ks ) , chondrosarcoma ( chs ) , `` '' dedifferentiated '' '' chondrosarcoma ( dchs ) , osteosarcoma ( os ) , epithelioid sarcoma ( es ) , and clear cell sarcoma ( ccs ; malignant melanoma of soft parts ) .
nichd_parent_of
{ "id": "C1261473", "name": "the", "pos": [ 11, 14 ] }
{ "id": "C0016057", "name": "fibrosarcoma", "pos": [ 293, 305 ] }
to test whether these observations are reproducible in the differential diagnosis of soft tissue sarcomas , anti-hla-dr antibodies lk8d3 and ln3 were applied to formalin-fixed , paraffin-embedded sections of mfh , neurofibrosarcoma ( nfs ) , leiomyosarcoma ( lms ) , synovial sarcoma ( ss ) , fibrosarcoma ( fs ) , angiosarcoma ( as ) , kaposi 's sarcoma ( ks ) , chondrosarcoma ( chs ) , `` '' dedifferentiated '' '' chondrosarcoma ( dchs ) , osteosarcoma ( os ) , epithelioid sarcoma ( es ) , and clear cell sarcoma ( ccs ; malignant melanoma of soft parts ) .
nichd_parent_of
{ "id": "C1261473", "name": "the", "pos": [ 11, 14 ] }
{ "id": "C0029463", "name": "osteosarco", "pos": [ 444, 454 ] }
enhanced infections are characterized by an increase in cytopathic effects and antigen synthesis as well as an increase in the production of progeny virus as detected by release of reverse transcriptase activity and infectious virus into the culture medium .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 9, 19 ] }
{ "id": "C0042769", "name": "infectious virus", "pos": [ 216, 232 ] }
in order to better define the natural history and anatomic variation of this disorder , we evaluated 41 patients by history , physical examination , and facial radiographs .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 91, 100 ] }
{ "id": "C0031809", "name": "physical examination", "pos": [ 126, 146 ] }
the authors conclude that while borderline disorder may be a sub-affective disorder , a specific diagnostic profile for this disorder that accounts for the presence of other axis i and axis ii syndromes has yet to be delineated .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 43, 51 ] }
{ "id": "C0039082", "name": "syndromes", "pos": [ 193, 202 ] }
to help establish such a protocol , the authors reviewed the charts and imaging records of 45 children and infants 12 years of age and younger who had fallen one to six stories .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 94, 102 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 107, 114 ] }
the finding of deep esophageal ulceration , intramural dissection , or fistula formation in a patient with aids should suggest the diagnosis of esophageal tuberculosis .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 4, 11 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 131, 140 ] }
on the basis of mr imaging characteristics , hiv encephalopathy could be distinguished from other lesions , particularly progressive multifocal leukoencephalopathy .
nichd_parent_of
{ "id": "C0085584", "name": "encephalopathy", "pos": [ 49, 63 ] }
{ "id": "C0023524", "name": "progressive multifocal", "pos": [ 121, 143 ] }
some of these complications are related to uremia and/or to the accumulation of endogenous toxic substances the nature of which has not been elucidated ( e.g . uraemic encephalopathy , polyneuropathy ) , while others are directly due to the haemodialysis itself ( e.g . dialysis disequilibrium syndrome , aluminum encephalopathy ) .
nichd_parent_of
{ "id": "C0009566", "name": "complications", "pos": [ 14, 27 ] }
{ "id": "C0403559", "name": "dialysis disequilibrium syndrome", "pos": [ 270, 302 ] }
the majority of patients with infection had more than one site of involvement and the following diagnoses were made by mri evaluation : osteomyelitis ( n = 8 ) , abscess ( n = 7 ) , neuropathic joint ( n = 5 ) , septic arthritis ( n = 4 ) , and tenosynovitis ( n = 4 ) .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 30, 39 ] }
{ "id": "C0000833", "name": "abscess", "pos": [ 162, 169 ] }
the neoplasm was surgically excised and proved to be a hemangioma ( fig . 4a ) and 4b ) .
nichd_parent_of
{ "id": "C0027651", "name": "neoplasm", "pos": [ 4, 12 ] }
{ "id": "C0018916", "name": "hemangioma", "pos": [ 55, 65 ] }
at term , fetuses showed spina bifida , including myeloschisis , myelocele , and diplomyelia ( diastematomyelia ) with abnormal distribution of ganglionic cells .
nichd_parent_of
{ "id": "C0080178", "name": "spina bifida", "pos": [ 25, 37 ] }
{ "id": "C0086664", "name": "myelocele", "pos": [ 65, 74 ] }
injuries sustained by falls or jumping to lower levels were relatively frequent while injuries caused by crushing , biting , cutting or stabbing were relatively rare and burns were not registered at all .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 0, 8 ] }
{ "id": "C0006434", "name": "burns", "pos": [ 170, 175 ] }
our evaluation included physical examinations , environmental sampling , and a questionnaire eliciting information concerning skin ulceration job history , demographics , and use of protective practices .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 4, 14 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 24, 32 ] }
the authors examined 112 subjects free from cardiac disease , with essential hypertension and myocardial infarction .
nichd_parent_of
{ "id": "C0018799", "name": "cardiac disease", "pos": [ 44, 59 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 94, 115 ] }
interstitial nephritis is a rare but serious adverse effect of many drugs and usually is diagnosed by clinical signs and symptoms of hematuria , proteinuria , eosinophilia , fever , azotemia , and rash .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 102, 116 ] }
{ "id": "C0015967", "name": "fever", "pos": [ 174, 179 ] }
interstitial nephritis is a rare but serious adverse effect of many drugs and usually is diagnosed by clinical signs and symptoms of hematuria , proteinuria , eosinophilia , fever , azotemia , and rash .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 102, 116 ] }
{ "id": "C0015230", "name": "rash", "pos": [ 197, 201 ] }
for the classification of hospital-wastes in the categories infectious-contaminate or special waste are only significant views of the prevention by nosocomial infection in the hospital .
nichd_parent_of
{ "id": "C0009450", "name": "infectious", "pos": [ 60, 70 ] }
{ "id": "C0205721", "name": "nosocomial infection", "pos": [ 148, 168 ] }
it has been estimated that of all new cancers diagnosed annually in the usa almost one third originate in the skin such as basal cell carcinoma , squamous cell carcinoma , and melanoma .
nichd_parent_of
{ "id": "C0006826", "name": "cancers", "pos": [ 38, 45 ] }
{ "id": "C0025202", "name": "melanoma", "pos": [ 176, 184 ] }
this permits recommending t. pallidum pathogenic strains to be maintained in mice at laboratories of institutions for skin and sexually transmitted diseases where experimental and diagnostic studies with the use of specific serologic tests for syphilis are carried out .
nichd_parent_of
{ "id": "C0036916", "name": "sexually transmitted diseases", "pos": [ 127, 156 ] }
{ "id": "C0039128", "name": "syphilis", "pos": [ 244, 252 ] }
positive eia results were recorded in 54.5 % of patients with the integument le forms and in 58.3 % of those with systemic le .
nichd_parent_of
{ "id": "C0409974", "name": "le", "pos": [ 77, 79 ] }
{ "id": "C0024141", "name": "systemic le", "pos": [ 114, 125 ] }
review is made to an account of contemporary knowledge on cell organelles in an attempt to describe organellopathies known at present together with their relations with diseases and syndromes .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 169, 177 ] }
{ "id": "C0039082", "name": "syndromes", "pos": [ 182, 191 ] }
in other inflammatory myopathies , expression of class i mhc was present on all fibers in polymyositis , only in the perifascicular area in dermatomyositis and in scleroderma .
nichd_parent_of
{ "id": "C0027121", "name": "inflammatory myopathies", "pos": [ 9, 32 ] }
{ "id": "C0085655", "name": "polymyositis", "pos": [ 90, 102 ] }
these findings are discussed in relation to results with monoclonal antibodies in other models of arthritis and human rheumatoid arthritis ;
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 98, 107 ] }
{ "id": "C0003873", "name": "rheumatoid arthritis", "pos": [ 118, 138 ] }
since these factors have been assigned an important pathogenic role in rheumatoid arthritis , self-aggregating igg rf , proposed to be induced by microbial igg fc receptors might be an important pathogenic factor in rheumatoid arthritis because rheumatoid arthritis is the only known condition where synthesis of rf takes place in the synovia .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 82, 91 ] }
{ "id": "C0003873", "name": "rheumatoid arthritis", "pos": [ 245, 265 ] }
and arrhythmias were observed in all subjects during sleep and consisted of transient bradycardia ( heart rates as low as 20 beats/min ) , sinus pauses frequently associated with escape rhythms and occasional blocked p waves .
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmias", "pos": [ 4, 15 ] }
{ "id": "C0428977", "name": "heart rates", "pos": [ 100, 111 ] }
the possible roles of underlying disease , bmt , and cmv liver disease are discussed in view of the recently reported cases of pct in patients with aids or hematological disorders .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 33, 40 ] }
{ "id": "C0018939", "name": "hematological disorders", "pos": [ 156, 179 ] }
however , the limited number of previous studies has not demonstrated any consistent excess mortality from diseases of a priori concern , such as lung cancer , non-malignant respiratory disease , and cardiovascular disease .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 107, 115 ] }
{ "id": "C0035204", "name": "respiratory disease", "pos": [ 174, 193 ] }
however , the limited number of previous studies has not demonstrated any consistent excess mortality from diseases of a priori concern , such as lung cancer , non-malignant respiratory disease , and cardiovascular disease .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 107, 115 ] }
{ "id": "C0007222", "name": "cardiovascular disease", "pos": [ 200, 222 ] }
in particular , nonpalpable pedal pulses were associated with more than a twofold excess of coronary heart disease ( p less than 0.05 ) and stroke ( p less than 0.01 ) in diabetic women and more than a twofold excess of coronary heart disease and cardiac failure in diabetic men ( p less than 0.01 ) .
nichd_parent_of
{ "id": "C0018799", "name": "of", "pos": [ 76, 78 ] }
{ "id": "C0018801", "name": "cardiac failure", "pos": [ 247, 262 ] }
the neonatal growth assessment score appears to be a sensitive indicator of third trimester growth retardation , is not affected by differences in growth potential , can separate normal infants from those with evidence of intrauterine growth retardation , and provides a quantitative assessment of growth problems in individual fetuses .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 317, 327 ] }
{ "id": "C0015965", "name": "fetuses", "pos": [ 328, 335 ] }
proliferative neoplasms that resemble malignant melanoma may develop in large congenital melanocytic nevi , prenatally or in the neonatal period , although these lesions rarely show the progressive growth or behavioral characteristics of melanoma .
nichd_parent_of
{ "id": "C0027651", "name": "neoplasms", "pos": [ 14, 23 ] }
{ "id": "C1318558", "name": "congenital melanocytic nevi", "pos": [ 78, 105 ] }
this report describes the genetic , biologic , and immunologic characteristics of six tissue culture cell lines derived from two neoplasms present in congenital melanocytic nevi in two newborn infants .
nichd_parent_of
{ "id": "C0027651", "name": "neoplasms", "pos": [ 129, 138 ] }
{ "id": "C1318558", "name": "congenital melanocytic nevi", "pos": [ 150, 177 ] }
the procedure of systematic palpation in relation to clinical diagnosis and surgical procedure is discussed .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0543467", "name": "surgical procedure", "pos": [ 76, 94 ] }
the surgical technique proved to enhance the safety of hypophysectomy , and the procedure can be recommended to treat clinical cases of canine pituitary-dependent hyperadrenocorticism .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 80, 89 ] }
{ "id": "C0087111", "name": "treat", "pos": [ 112, 117 ] }
they were referred for evaluation of presumptive sleep apnea syndrome on the basis of history and physical examination , but were found to have predominantly csr on all-night sleep study .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 23, 33 ] }
{ "id": "C0031809", "name": "physical examination", "pos": [ 98, 118 ] }
between 1983 and 1988 , with the use of infusion of prostaglandin e in the neonatal period , 28 children underwent a senning procedure at a mean age of 12 months with a surgical mortality of 17.8 % , and an actuarial survival rate of 80.9 % .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 125, 134 ] }
{ "id": "C0543467", "name": "surgical", "pos": [ 169, 177 ] }
it is concluded that while intrarenal vasculopathy with thrombosis and nephrosclerosis is a common finding in sle , our data and recently published studies suggest that acute necrotizing vasculitis occurs rarely , if at all , in sle nephritis .
nichd_parent_of
{ "id": "C0042373", "name": "vasculopathy", "pos": [ 38, 50 ] }
{ "id": "C0040053", "name": "thrombosis", "pos": [ 56, 66 ] }
tosufloxacin ( a-60969 hcl ) , a new quinolone with broad activity against gram-positive and anaerobic organisms , was compared in vitro with other quinolones against bacterial pathogens of diarrhea .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 103, 112 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 177, 186 ] }
other vascular complications included hepatic artery stenosis not complicated by thrombosis ( two ) , primary ( one ) and secondary ( one ) haemorrhage , thrombosis of a mesoportal venous graft ( one ) and inferior vena caval stenosis ( one ) .
nichd_parent_of
{ "id": "C0040053", "name": "thrombosis", "pos": [ 81, 91 ] }
{ "id": "C0042487", "name": "thrombosis", "pos": [ 154, 164 ] }
in view of the similar outcome and severity of coronary disease in those aged less than or equal to 70 with non q wave infarcts , the distinction between q and non q wave infarction need not influence management decisions in patients after myocardial infarction .
nichd_parent_of
{ "id": "C0021308", "name": "infarction", "pos": [ 171, 181 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 240, 261 ] }
among the cancers , statistically significant excesses occurred for oesophagus ( smr = 2.1 ) and cervix ( smr = 1.7 ) and non-significant excesses for larynx ( smr = 1.6 ) , lung ( smr = 1.3 ) , bladder ( smr = 1.7 ) , thyroid ( smr = 3.3 ) , lymphosarcoma and reticulosarcoma ( smr = 1.7 ) , and hodgkin 's disease ( smr = 2.1 ) .
nichd_parent_of
{ "id": "C0006826", "name": "cancers", "pos": [ 10, 17 ] }
{ "id": "C0024299", "name": "lymphosarcoma", "pos": [ 243, 256 ] }
we describe a white french family in which 12 subjects presented with hereditary elliptocytosis ( he ) or hereditary pyropoikilocytosis ( hpp ) .
nichd_parent_of
{ "id": "C0013902", "name": "hereditary", "pos": [ 70, 80 ] }
{ "id": "C0520739", "name": "hereditary pyropoikilocytosis", "pos": [ 106, 135 ] }
hybridization of amplified dnas with allele-specific oligonucleotides corresponding to the normal and mutant sequences confirmed the presence of the mutation in six other he and hpp members of the family .
nichd_parent_of
{ "id": "C0013902", "name": "he", "pos": [ 88, 90 ] }
{ "id": "C0520739", "name": "hpp", "pos": [ 178, 181 ] }
furthermore , discrepancies in previous findings on the effects of parity on ability to obtain fluid may be explained by our finding that the increased ability to obtain fluid from parous compared to nulliparous women applied only to parous women who had breastfed .
nichd_parent_of
{ "id": "C0030563", "name": "parity", "pos": [ 67, 73 ] }
{ "id": "C0425979", "name": "nulliparous", "pos": [ 200, 211 ] }
a prospective study was carried out by the department of ophthalmology and the division of infectious disease at the children 's hospital of eastern ontario to assess the outcome of our medical management of orbital cellulitis in children using a predetermined antibiotic regimen and to determine whether computed tomographic ( ct ) evidence of a subperiosteal abscess alone was an indication for surgical drainage .
nichd_parent_of
{ "id": "C0009450", "name": "infectious disease", "pos": [ 91, 109 ] }
{ "id": "C0000833", "name": "abscess", "pos": [ 361, 368 ] }
continual use of such products , especially by small children and infants , may significantly increase their exposure to ndela .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 53, 61 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 66, 73 ] }
the combination of gm-csf production by the tumor and tnf production by immune cells may influence not only tumor growth but also some of the paraneoplastic syndromes associated with malignancy such as hypercalcemia , cachexia and leukocytosis .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 44, 49 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 183, 193 ] }
this observation supports the suggestion of a possible role of procarbazine-induced o6-methylguanine in the pathogenesis of acute nonlymphocytic leukemia appearing after treatment with chemotherapeutic protocols which include procarbazine , based on the finding of low lymphocyte agt levels in patients with such therapy-related neoplastic disease ( sagher et al. , cancer res. , 48 : 3084-3089 , 1988 ) .
nichd_parent_of
{ "id": "C0027651", "name": "neoplastic disease", "pos": [ 329, 347 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 366, 372 ] }
influence of reflow ventricular fibrillation and electrical defibrillation on infarct size in a canine preparation of myocardial infarction .
nichd_parent_of
{ "id": "C0021308", "name": "infarct", "pos": [ 78, 85 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 118, 139 ] }
bivariate and linear discriminant analyses revealed that , above all , variables related to bacterial infections ( sepsis and administration of antibiotic agents ) and pancreatitis contributed to the discrimination , followed by bleeding , volume depletion , and chronic liver disease in the discriminant function .
nichd_parent_of
{ "id": "C0004623", "name": "bacterial infections", "pos": [ 92, 112 ] }
{ "id": "C0036690", "name": "sepsis", "pos": [ 115, 121 ] }
recent advances in sexually transmitted diseases : reflections on the center for disease control 's new sexually transmitted diseases treatment guidelines from the viewpoint of a private practitioner : human immunodeficiency virus ( hiv ) , genital ulcers , chancroid , and syphilis .
nichd_parent_of
{ "id": "C0036916", "name": "sexually transmitted diseases", "pos": [ 19, 48 ] }
{ "id": "C0039128", "name": "syphilis", "pos": [ 274, 282 ] }
taking into consideration problems in trial design and evaluation of the effects of treatment , and the amount of documentation , it may be concluded that propranolol , metoprolol , timolol , nadolol and atenolol have been shown to reduce the frequency of migraine attacks in patients with common as well as classical migraine .
nichd_parent_of
{ "id": "C0149931", "name": "migraine", "pos": [ 256, 264 ] }
{ "id": "C0154723", "name": "classical migraine", "pos": [ 308, 326 ] }
the ability of flunarizine to reduce the frequency of migraine attacks in patients with common and classical migraine is well documented ;
nichd_parent_of
{ "id": "C0149931", "name": "migraine", "pos": [ 54, 62 ] }
{ "id": "C0154723", "name": "classical migraine", "pos": [ 99, 117 ] }
the electroclinical manifestations of seizures are important data to consider in the diagnosis and treatment of extratemporal seizure foci .
nichd_parent_of
{ "id": "C0036572", "name": "seizures", "pos": [ 38, 46 ] }
{ "id": "C0751495", "name": "seizure foci", "pos": [ 126, 138 ] }
within 100 years , the interpretation of this disease changed repeatedly and considerably : infection of particularly exposed organs -- non-avirulent tuberculosis -- salivotropic virus -- boeck 's disease -- allergic-hyperergic reaction -- diencephalic and nervous dystrophy with segmental projection -- ( auto ) immune disease -- oculo-salivary complex including sjogren 's syndrome -- all these were discussed as possible aetiologies .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 46, 53 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 92, 101 ] }
within 100 years , the interpretation of this disease changed repeatedly and considerably : infection of particularly exposed organs -- non-avirulent tuberculosis -- salivotropic virus -- boeck 's disease -- allergic-hyperergic reaction -- diencephalic and nervous dystrophy with segmental projection -- ( auto ) immune disease -- oculo-salivary complex including sjogren 's syndrome -- all these were discussed as possible aetiologies .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 46, 53 ] }
{ "id": "C0021053", "name": "immune disease", "pos": [ 313, 327 ] }
moreover , if the exclusion of nontelephone households simply underestimates the proportions in the population with certain characteristics , such as age and ethnicity , and the `` '' true '' '' proportions are known , it is possible to appropriately weight the study group in order to mitigate the telephone-exclusion bias .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 124, 139 ] }
{ "id": "C0005910", "name": "weig", "pos": [ 251, 255 ] }
diseases included upper respiratory tract infections , abscesses , ear infections , lower urinary tract infections , gastrointestinal disease , pneumonia , uterine infection , lymphadenopathy , fever of unknown origin , and bacterial infections .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 0, 8 ] }
{ "id": "C0017178", "name": "gastrointestinal disease", "pos": [ 117, 141 ] }
common clinical signs of disease observed by owners of horses in both groups included anorexia , weight loss , fever , signs of colic , and depression .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 7, 21 ] }
{ "id": "C0003123", "name": "anorexia", "pos": [ 86, 94 ] }
common clinical signs of disease observed by owners of horses in both groups included anorexia , weight loss , fever , signs of colic , and depression .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 7, 21 ] }
{ "id": "C0015967", "name": "fever", "pos": [ 111, 116 ] }