text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
these endocrinological features of tubular adenomas were consistent with the following pathological features of the sl/slt mice with the tumors : ( a ) although the weight of uterus of the sl/slt mice was about one-half of the value observed in the +/+ mice , it decreased markedly after oophorectomy ; | nichd_parent_of | {
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cl-920 failed to show confirmed activity against the following tumors in mice : m5076 sarcoma , b16 melanoma , and ridgway osteogenic sarcoma . | nichd_parent_of | {
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"name": "osteogenic sarcoma",
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a progressive increase in malignancy , accompanied by a loss of sensitivity to levan , were observed following serial passage of the lymphoma . | nichd_parent_of | {
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treatment of advanced soft tissue sarcomas with low-dose methotrexate : a phase ii trial by the european organization of research on treatment for cancer ( eortc ) soft tissue and bone sarcoma group . | nichd_parent_of | {
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self-ratings with respect to headache and five mood dimensions were obtained twice daily from five patients suffering from migraine and six patients suffering from muscle-contraction headache during a mean period of 47.9 days ( range : 38-61 ) . | nichd_parent_of | {
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indomethacin exerts an absolute , persistent and clearly dose-dependent effect on this headache , which differs from unilateral headache syndromes such as cluster headache and cervicogenic headache in its temporal pattern and indomethacin response . | nichd_parent_of | {
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} | {
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the tissues were grouped as control placentae from 20 normal pregnancies and 20 from cases of pre-eclampsia ( pe ) : the pe samples were sub-grouped as being obtained from patients with mild or severe pe . | nichd_parent_of | {
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the incidence of the anti-vdrl antibody in the igg class was 29.2 % and 25 % in the igm class , and the magnitude of these antibodies correlated well with the incidence of biological false positive serological test for syphilis ( bfp-sts ) , but no association between the anti-vdrl antibody titre and the anti-cardiolipin antibody titre was observed . | nichd_parent_of | {
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} | {
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patients with non-q wave infarction had a higher incidence of stable angina before the myocardial infarction and a lower value of creatine kinase ( ck ) and serum glutamic oxalacetic transferase ( sgot ) . | nichd_parent_of | {
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the effect of renal disease on lorazepam kinetics was assessed in three groups : six normal subjects , six patients with renal impairment , and four functionally anephric patients . | nichd_parent_of | {
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} | {
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( i ) questionnaire ( ii ) clinical examination and interview with all employees who stated that they had had skin disease at some time ( iii ) patch testing at the laboratory of all cases of suspected occupational dermatoses , and control tests in hospital of 200 non-exposed eczema patients ( iv ) investigation of protective gloves by patch testing and in a chemical bath ( v ) allergy test on guinea pigs ( gpmt ) of one agent ( pba-1 ) . | nichd_parent_of | {
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} | {
"id": "C0013595",
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283
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a rapid assay procedure to evaluate the metabolism of a given 14c-labeled chemical in plant cell suspension cultures is described . | nichd_parent_of | {
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in radioisotopic blood pool study venous aneurysm , unlike arterial or aortic aneurysm , may be filled to the equilibrium state later than the appearance of the cardiac pool . | nichd_parent_of | {
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} | {
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these results are discussed in the context of retinoid treatment of skin diseases such as psoriasis where inhibition of neutrophil accumulation during retinoid treatment has been reported . | nichd_parent_of | {
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with this technique the risks of complications due to an incorrect location of the catheter are minimized and the outcome of the procedure can be immediately evaluated by measuring the size of the atrial septal defect . | nichd_parent_of | {
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a spontaneous fall in the level of alpha-fetoprotein is not an uncommon finding in the early stages of this cancer and can not be used to rule out the diagnosis of hepatocellular carcinoma . | nichd_parent_of | {
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the relationship between variability of the heterochromatic regions of chromosomes 1 , 9 , 16 , y and the anthropometric characteristics ( the height , the biacromial diameter and weight ) was studied in two groups of children ; | nichd_parent_of | {
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136
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} | {
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a patient with a year-long history of metatarsalgia was found to have an elevated platelet count due to essential thrombocythemia , a benign myeloproliferative disease . | nichd_parent_of | {
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"name": "elevated platelet count",
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} | {
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"name": "essential thrombocythemia",
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in patients with a history of malignant arrhythmias in whom no evidence of high-grade ventricular arrhythmias can be found in either the continuous ekg recording or in the exercise ekg , initiation of drug treatment should be based on the results of programmed electrical stimulation . | nichd_parent_of | {
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} | {
"id": "C0085612",
"name": "ventricular arrhythmias",
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} |
madin-darby canine kidney ( mdck ) cells can sustain double infection with pairs of viruses of opposite budding polarity ( simian virus 5 [ sv5 ] and vesicular stomatitis virus [ vsv ] or influenza and vsv ) , and we observed that in such cells the envelope glycoproteins of the two viruses are synthesized simultaneously and assembled into virions at their characteristic sites . | nichd_parent_of | {
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} | {
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in addition , the high-malignant cells ( but not the low ) secreted a material into the cell culture fluid that could be specifically immunoprecipitated with antilaminin antibodies . | nichd_parent_of | {
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observations were performed on 45 very low birth weight ( vlbw ) newborns at 7 and 21 days of life , using a neonatal behavioral assessment scale specifically modified for the extremely premature infant . | nichd_parent_of | {
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} | {
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} |
organisms were isolated from 70 % of the pretreatment quarter samples , but only 13 % of the isolates were major pathogens . | nichd_parent_of | {
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} | {
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six experiments were to test for estrus-associated odors in 1 ) swabs of the vulva and vestibule , 2 ) fluids from deep in the vagina , 3 ) naturally voided urine , 4 ) urine obtained from the bladder by catheter , 5 ) milk , and 6 ) blood plasma . | nichd_parent_of | {
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} | {
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} |
complications classified as major were : mediastinal hemorrhage , pericardial tamponade , wound dehiscence , sternal osteomyelitis , myocardial infarction , bacterial endocarditis , dissecting aneurysm and diabetes insipidus . | nichd_parent_of | {
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} | {
"id": "C0259768",
"name": "wound dehiscence",
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primary gastric lymphoma comprised 20 % of 119 patients with gastric malignancy seen at our hospital between 1975 and 1980 , even when strict criteria were applied to exclude systemic lymphoma patients with gastric involvement . | nichd_parent_of | {
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} | {
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"name": "lymphoma",
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192
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} |
the quantitative range of this type of conjugates , where reactivities are linearly proportional to the amount of human ig present , is , however , extremely narrow ( 0.01-0.10 micrograms/ml of human igg ) . | nichd_parent_of | {
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} | {
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conjugates prepared with glutaraldehyde are thus more useful in quantitative assays where wide quantitative ranges are desirable . | nichd_parent_of | {
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} | {
"id": "C1514721",
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residual clinical signs such as motor weakness and absent patellar tendon reflexes were found in 16 ( 52 % ) of those patients who had had a preceding illness . | nichd_parent_of | {
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23
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} | {
"id": "C3714552",
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} |
repeated cerebral blood flow ( cbf ) measurements with xenon-133 inhalation and single photon emission tomography were performed in a patient suffering a minor stroke with subsequent orthostatic-provoked transient ischemic attacks ( tia 's ) . | nichd_parent_of | {
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160,
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} | {
"id": "C0007787",
"name": "tia 's",
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233,
239
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} |
the effectiveness of methylprednisolone for the reduction of postoperative facial edema was evaluated by the computed tomographic examination of 39 patients who underwent either a lefort i osteotomy or a transoral vertical osteotomy . | nichd_parent_of | {
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} | {
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} |
a modified sweat test procedure was studied to evaluate its practicability in the diagnosis of cystic fibrosis in newborn infants . | nichd_parent_of | {
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the analytical method was shown to give quantitative recovery of the drug and metabolite , to be linear over a 100-fold concentration range , and to have the necessary precision and sensitivity to detect and quantify as little as 1 ng/ml of the drug or its metabolite . | nichd_parent_of | {
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} | {
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} |
twenty-nine cases of shr from 670 fetal heart rate tracings were correlated with narcotic analgesic use and perinatal outcome . | nichd_parent_of | {
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} | {
"id": "C0018811",
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} |
the haematological features of g gamma a gamma delta beta ( 0 ) -thalassaemia carriers are compared with those of beta-thalassaemia and hb lepore heterozygotes . | nichd_parent_of | {
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} | {
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in response to a second survey , many senior residents said they did not feel competent to perform these 19 procedures , and many did not recall that their performance on procedures had been evaluated . | nichd_parent_of | {
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animals received 5 or 10 daily treatments of 0 , 125 , 200 , 250 , 500 , or 1000 mg benomyl/kg . d by gavage . | nichd_parent_of | {
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} | {
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these effects were judged not to be toxicologically significant , since mammary tumor incidences did not exceed expected incidences in aged female sprague-dawley rats , time to tumor appearance was unchanged , and no shift in percent benign versus malignant tumors occurred . | nichd_parent_of | {
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} | {
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} |
it was elicited that those not involved in the study showed a greater predominance of chd risk factors ( arterial hypertension , smoking , underexercise and personality psychological type a ) and a greater proportion of myocardial infarction survivers ( 3.87 % and 1.49 % , respectively ) . | nichd_parent_of | {
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} | {
"id": "C0027051",
"name": "myocardial infarction",
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220,
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} |
letterer-siwe 's disease ( acute disseminated histiocytosis x ) : a case complicated by disseminated intravascular coagulation and responding to heparin therapy . | nichd_parent_of | {
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} | {
"id": "C0023381",
"name": "acute disseminated histiocytosis x",
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on the mechanism of renal potassium wasting in renal tubular acidosis associated with the fanconi syndrome ( type 2 rta ) . | nichd_parent_of | {
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"name": "renal tubular acidosis",
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} | {
"id": "C0268435",
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109,
119
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} |
the mechanism of renal potassium wasting in renal tubular acidosis associated with the fanconi syndrome ( type 2 rta ) was investigated in 10 patients , each of whom had impaired proximal renal tubular reabsorption of bicarbonate as judged from a greater than 15-20 % reduction of renal tubular bicarbonate reabsorption ( thco ( 3 ) ( - ) ) at normal plasma bicarbonate concentrations . | nichd_parent_of | {
"id": "C0001126",
"name": "renal tubular acidosis",
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} | {
"id": "C0268435",
"name": "type 2 rta",
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106,
116
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} |
this procedure had a beneficial effect on the waiting list , and expensive beds were used more efficiently for major surgical cases . | nichd_parent_of | {
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} | {
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} |
measurements of spin-lattice ( t ( 1 ) ) and spin-spin ( t ( 2 ) ) magnetic relaxation times were made in six normal tissues in the rat ( muscle , kidney , stomach , intestine , brain , and liver ) and in two malignant solid tumors , walker sarcoma and novikoff hepatoma . | nichd_parent_of | {
"id": "C0006826",
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} | {
"id": "C1261473",
"name": "sarcoma",
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} |
the average number of antigen-sensitive cells detected in cell populations from donors reacting to first test strength or intermediate test strength tuberculin was approximately 3.6/1000 lymphocytes , and the averages for both groups were similar . | nichd_parent_of | {
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109
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} | {
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} |
a gas chromatographic procedure for determining estriol in pregnancy urine : evaluation in two different laboratories . | nichd_parent_of | {
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22,
31
]
} | {
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} |
objective versus individual mental ability tests with former head start children in the first grade . | nichd_parent_of | {
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27
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} | {
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"name": "children",
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} |
this bimodal response characteristic is unlike the modality specificity noted for other primary sensory fields . | nichd_parent_of | {
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} | {
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} |
the behavioral arousal threshold in infant sleep as a function of time and sleep state . | nichd_parent_of | {
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4,
14
]
} | {
"id": "C0037313",
"name": "sleep",
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75,
80
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} |
it was necessary to prepare virus stocks from clones of mutagenized virus selected at random and to test subsequently each stock for possible ts characteristics by measuring its relative capacity for growth at permissive ( 33 c ) and nonpermissive ( 40.5 c ) temperatures . | nichd_parent_of | {
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160
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} | {
"id": "C0039476",
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259,
271
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} |
in regard to other diseases , bence jones proteinuria was found in 44 % of patients with macroglobulinemia , in 60 % of patients with nonplasmacytic neoplastic diseases and in 28 % of patients with non-malignant conditions . | nichd_parent_of | {
"id": "C0012634",
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} | {
"id": "C0027651",
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149,
168
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} |
[ histologic picture report no 248. vascular diseases of the vulva ( 1 ) . 1. hemangioma . 2. granuloma pyogenicum teleangiectaticum ] . | nichd_parent_of | {
"id": "C0018916",
"name": "hemangioma",
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} | {
"id": "C0085653",
"name": "granuloma pyogenicum",
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94,
114
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} |
[ patricide as an expression of emotional disorders in a subject with a tumor in the parietal region of the brain ] . | nichd_parent_of | {
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"name": "disorders",
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42,
51
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
72,
77
]
} |
[ internally directed effects of dermatoses . retrospective view on isam miyake and his studies on the influence of experimental contact dermatitis on the whole organism ] . | nichd_parent_of | {
"id": "C0037274",
"name": "dermatoses",
"pos": [
33,
43
]
} | {
"id": "C0011616",
"name": "contact dermatitis",
"pos": [
129,
147
]
} |
patients with various forms of glomerulonephritis , but excluding those with minimal glomerular changes , were admitted to a controlled trial of a regimen which combined azathioprine in a dosage of 2.5 mg/kg/day with prednisone in a dosage of 20 mg/day ( adults ) or 0.5 mg/kg/day ( children ) . | nichd_parent_of | {
"id": "C0017658",
"name": "glomerulonephritis",
"pos": [
31,
49
]
} | {
"id": "C0027721",
"name": "minimal glomerular changes",
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77,
103
]
} |
the increased use of the low transverse incision would greatly reduce the serious complication of wound dehiscence after caesarean section . | nichd_parent_of | {
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"name": "complication",
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82,
94
]
} | {
"id": "C0259768",
"name": "of wound",
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95,
103
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} |
the metabolite , the reduced product , is the principal substance to be encountered in these fluids . | nichd_parent_of | {
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65
]
} | {
"id": "C0005889",
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93,
99
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} |
this account of the conduct of the similium control scheme at abuja , northern nigeria , over the period 1956-66 shows that , by larvicide treatment of some 160 km of rivers with ddt in the early wet season , the simulium damnosum density has been reduced by about 90 % of its precontrol level each year over an area of more than 3000 km ( 2 ) .a skin-snip survey , in which 6748 persons were examined ( of whom 5700 lived within the controlled area and 1048 in a comparison area ) during 1966 , indicates that there has been no obvious decrease in prevalence of onchocerciasis , particularly among children born since the commencement of the scheme , that could be attributed solely to the effects of the control measures , although there are indications that a drop in severity of infection has been achieved . | nichd_parent_of | {
"id": "C0027361",
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380,
387
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
599,
607
]
} |
present knowledge of experimental infection of non-human primates with variola virus and of a related virus infection in monkeys , termed monkeypox , is examined . | nichd_parent_of | {
"id": "C0042769",
"name": "virus infection",
"pos": [
102,
117
]
} | {
"id": "C0276180",
"name": "monkeypox",
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138,
147
]
} |
the distribution of leukaemia in time and space was examined by tracing the date of onset and the place of residence in all cases of childhood leukaemia and of acute leukaemia in adults , totalling 1,003 cases , which occurred in new zealand during the 12 years from 1953 to 1964 . | nichd_parent_of | {
"id": "C0023418",
"name": "distribution",
"pos": [
4,
16
]
} | {
"id": "C1332977",
"name": "childhood leukaemia",
"pos": [
133,
152
]
} |
in thalassaemia , which causes a lowered production of haemoglobin , the alpha or the beta chain can be affected , the result being alpha- or beta-thalassaemia . | nichd_parent_of | {
"id": "C0039730",
"name": "thalassaemia",
"pos": [
3,
15
]
} | {
"id": "C0005283",
"name": "beta-thalassaemia",
"pos": [
142,
159
]
} |
the effects of posterior hypothalamic lesions on behavioral and electrographic manifestations of sleep and waking in cats . | nichd_parent_of | {
"id": "C0004927",
"name": "behavioral",
"pos": [
49,
59
]
} | {
"id": "C0037313",
"name": "sleep",
"pos": [
97,
102
]
} |
[ effects of the combined administration of a triple vaccine of pertussis , diphtheria and tetanus and virus vaccine ( live polio vaccine or inactivated measles vaccine ) on immunity to pertussis , diphtheria and tetanus . 1. results of the initial immunization ] . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
53,
60
]
} | {
"id": "C0042212",
"name": "inactivated",
"pos": [
141,
152
]
} |
[ effects of the combined administration of a triple vaccine of pertussis , diphtheria and tetanus and virus vaccine ( live polio vaccine or inactivated measles vaccine ) on the immunity of pertussis , diphtheria and tetanus . 2. observations during the intervals from the initial immunization to the time of booster dose and the effects of successive immunization ] . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
53,
60
]
} | {
"id": "C0042212",
"name": "inactivated",
"pos": [
141,
152
]
} |
a new immunodiffusion method for quantitative determination of proteins in biological fluids based on a separate application of antibody and antigen to small agar discs . | nichd_parent_of | {
"id": "C0005889",
"name": "fluids",
"pos": [
86,
92
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
128,
136
]
} |
the general morphology and physiology of this organism is similar to that of the pasteurellae and several known fish pathogens . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
46,
54
]
} | {
"id": "C0450254",
"name": "pathogens",
"pos": [
117,
126
]
} |
organisms having a complex life cycle similar to the animal pathogen dermatophilus congolensis have been isolated from soils of the united states . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
0,
9
]
} | {
"id": "C0450254",
"name": "pathogen",
"pos": [
60,
68
]
} |
[ immunofluorescent studies on the type-specific antigen of the tsutsugamushi disease rickettsia -- with special reference to the antigen analysis in infection with several standard strains ] . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
78,
85
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
150,
159
]
} |
[ some indices of the functioal condition of the cardiovascular system during experimental hypertension in animals of various ages ] . | nichd_parent_of | {
"id": "C0007222",
"name": "of the",
"pos": [
15,
21
]
} | {
"id": "C0020538",
"name": "hypertension",
"pos": [
91,
103
]
} |
[ current clinical problems in liver and kidney diseases . ii . fatty liver , alcoholic liver cirrhosis , chronic hepatitis , mushroom poisoning , liver metastases , hepatoma , nephrotic syndrome , kidney damage by phenacetin ] . | nichd_parent_of | {
"id": "C0022658",
"name": "kidney diseases",
"pos": [
41,
56
]
} | {
"id": "C0027726",
"name": "nephrotic syndrome",
"pos": [
177,
195
]
} |
reviewing the literature on hydatid serology for the period 1958-66 , the author concludes that the complement-fixation test is not the most sensitive procedure but may have value for postoperative evaluation . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
151,
160
]
} | {
"id": "C0220825",
"name": "evaluation",
"pos": [
198,
208
]
} |
the other variant , which was pathogenic for rhesus monkeys , was characterized by greater immunogenicity but when given as a live vaccine caused acutely febrile reactions and other side-effects in 10 % of inoculated persons 6 to 8 days after administration.in persons vaccinated with the avirulent vaccine , the antibodies were maintained for over 3 years compared with only 1 year after administration of a killed vaccine . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
131,
138
]
} | {
"id": "C0042212",
"name": "killed vaccine",
"pos": [
409,
423
]
} |
antibody specific for viral neuraminidase can be demonstrated in mice following ( i ) pulmonary infection with influenza virus , ( ii ) immunization with ultraviolet-in-activated influenza virus , ( iii ) immunization with isolated neuraminidase of influenza a ( 2 ) virus , and ( iv ) passive immunization with sera of rabbits immunized with isolated a ( 2 ) neuraminidase . | nichd_parent_of | {
"id": "C0020971",
"name": "immunization",
"pos": [
136,
148
]
} | {
"id": "C0042200",
"name": "immunization",
"pos": [
294,
306
]
} |
[ current clinical problems in liver and kidney diseases . i. fatty liver , alcoholic liver cirrhosis , chronic hepatitis , mushroom poisoning , liver metastases , hepatoma , nephrotic syndrome , kidney damage by phenacetin ] . | nichd_parent_of | {
"id": "C0022658",
"name": "kidney diseases",
"pos": [
41,
56
]
} | {
"id": "C0027726",
"name": "nephrotic syndrome",
"pos": [
175,
193
]
} |
the authors compared 2 methods of apheresis : plasmapheresis ( pa ) and lymphocytoplasmapheresis ( lpa ) in 24 patients with rheumatoid arthritis ( ra ) . | nichd_parent_of | {
"id": "C0005791",
"name": "apheresis",
"pos": [
34,
43
]
} | {
"id": "C0032134",
"name": "plasmapheresis",
"pos": [
82,
96
]
} |
the patients were divided into 2 groups : with chronic pyelonephritis in the phase of active inflammation and with chronic pyelonephritis in the phase of remission . | nichd_parent_of | {
"id": "C0034186",
"name": "pyelonephritis",
"pos": [
55,
69
]
} | {
"id": "C0085697",
"name": "chronic pyelonephritis",
"pos": [
115,
137
]
} |
metastasis of cancer to cancer is exceedingly rare , the most frequent being metastasis from bronchogenic carcinoma to renal carcinoma . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
14,
20
]
} | {
"id": "C0007134",
"name": "renal carcinoma",
"pos": [
119,
134
]
} |
the analysis of these experiments demonstrates the usefulness of a powerful statistical procedure for evaluating the biological effects resulting from exposure to multiple cytotoxic agents . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
88,
97
]
} | {
"id": "C0220825",
"name": "evaluating",
"pos": [
102,
112
]
} |
however , the time course of serum citrate elevations corresponded with the appearance of serious clinical signs and death . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
98,
112
]
} | {
"id": "C0011065",
"name": "death",
"pos": [
117,
122
]
} |
contrast ct scans may detect patients at risk for post-endarterectomy hemorrhage even 2 months after a stroke or tia . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
103,
109
]
} | {
"id": "C0007787",
"name": "tia",
"pos": [
113,
116
]
} |
studying the elimination of marek 's disease virus by feather follicles , the health condition of chickens , tumor frequency and mortality rate we demonstrated that neither of these doses could protect the chickens from the disease if they were exposed to contact infection just after vaccination . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
37,
44
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
264,
273
]
} |
increasing incidence of crohn 's disease particularly in childhood and adolescence has made inflammatory bowel disease one of the most important aspects of paediatric gastroenterology . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
57,
66
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
71,
82
]
} |
the clinical consequences of the results described here include the early use of the antepartal cardiotocogram in cases of complications during pregnancy involving hypoxia ( such as toxemia of pregnancy , premature labor , suspected intrauterine retardation of growth ) , as well as an increase in the frequency of ctg examinations , even to the point of continuous external cardiotocographic observation and , if other gestational complications involving hypoxia , especially the threat of premature birth , arise , the generous use of primary cesarean section . | nichd_parent_of | {
"id": "C0009566",
"name": "complications",
"pos": [
123,
136
]
} | {
"id": "C0032962",
"name": "gestational complications",
"pos": [
420,
445
]
} |
in the here presented case a very rare disease is the cause for the dilatation of the fetal bladder , the megacystis-microcolon-hypoperistalsis-syndrome . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
39,
46
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
144,
152
]
} |
serum levels of igg and especially iga and the incidence of auto-antibodies ( antinuclear antibody and rheumatoid factor ) were increased in aged subjects . | nichd_parent_of | {
"id": "C0003241",
"name": "antibodies",
"pos": [
65,
75
]
} | {
"id": "C0003243",
"name": "antinuclear antibody",
"pos": [
78,
98
]
} |
a series of man-chinese hamster hybrids were investigated with the use of an anti-chinese hamster hexosaminidase serum , a specific anti-human hex a serum and an anti-human hex b serum . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
137,
142
]
} | {
"id": "C1415537",
"name": "hex",
"pos": [
173,
176
]
} |
the recent advances in the understanding of the major histocompatibility complex , particularly of human hla and murine h2 , are critically reviewed . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
99,
104
]
} | {
"id": "C0919509",
"name": "h2",
"pos": [
120,
122
]
} |
analysis of the presence or absence of human trp-rs and other human enzyme markers in eleven independently dervied cell lines of human-mouse somatic cell hybrids revealed that the expression of trp-rs is correlated with the expression of human nucleoside phosphorylase ( np , ec 2.4.2.1 ) . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
39,
44
]
} | {
"id": "C1706141",
"name": "np",
"pos": [
271,
273
]
} |
we have developed an autoradiographic/electrophoretic assay capable of distinguishing mouse and human beta2-microglobulin ( beta2m ) in spent culture media . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
96,
101
]
} | {
"id": "C1417683",
"name": "beta2",
"pos": [
124,
129
]
} |
with this technique , mouse/human hybrid cell lines were tested for the presence of human beta2m . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
28,
33
]
} | {
"id": "C1417683",
"name": "beta2m",
"pos": [
90,
96
]
} |
primary injection of human serum stimulates the formation of precipitin antibodies to beta2 lipoprotein in dogs , beta2 lipoprotein and beta globulin in rabbits . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
21,
26
]
} | {
"id": "C1417683",
"name": "beta2",
"pos": [
114,
119
]
} |
after a secondary dose the rabbits formed precipitins to a whole range of human serum proteins , while the dogs to beta2 lipoprotein , albumin , beta globulin . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
74,
79
]
} | {
"id": "C1417683",
"name": "beta2",
"pos": [
115,
120
]
} |
the 7.2 kb species , which is presumably the genome of amv , appears to contain the entire retroviral gag gene and at least part of the pol gene , but lacks much ( or all ) of the env gene . | organism_has_gene | {
"id": "C0035366",
"name": "retroviral",
"pos": [
91,
101
]
} | {
"id": "C0017346",
"name": "gag gene",
"pos": [
102,
110
]
} |
the 7.2 kb species , which is presumably the genome of amv , appears to contain the entire retroviral gag gene and at least part of the pol gene , but lacks much ( or all ) of the env gene . | organism_has_gene | {
"id": "C0035366",
"name": "retroviral",
"pos": [
91,
101
]
} | {
"id": "C0017360",
"name": "pol gene",
"pos": [
136,
144
]
} |
the 7.2 kb species , which is presumably the genome of amv , appears to contain the entire retroviral gag gene and at least part of the pol gene , but lacks much ( or all ) of the env gene . | organism_has_gene | {
"id": "C0035366",
"name": "retroviral",
"pos": [
91,
101
]
} | {
"id": "C0017343",
"name": "env gene",
"pos": [
180,
188
]
} |
the available amino acid sequence data indicate extensive homology between human and mouse heavy chains . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
75,
80
]
} | {
"id": "C1420192",
"name": "heavy chains",
"pos": [
91,
103
]
} |
the binding of chromosomal proteins to cloned mouse and human globin genes can be determined by transferring proteins from one dimensional electrophoretic separations on to nitrocellulose paper and exposing them to nick translated cloned globin dnas . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
56,
61
]
} | {
"id": "C3825351",
"name": "globin genes",
"pos": [
62,
74
]
} |
[ human pharmacokinetics of the new potent analgesic dl-trans-2-di-methylamino-1-phenyl-cyclohex-3-en-trans-1-carboxylic acid ethyl ester hydrochloride . 1. blood level and excretion with urine and feces after single oral administration of 14c-labeled substance ] . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
2,
7
]
} | {
"id": "C3538902",
"name": "di",
"pos": [
64,
66
]
} |
phagocytosis of e. coli and k. pneumoniae by human polymorphonuclear neutrophil was more enhanced in the presence of 1 mic and 1/2 mic of czx than of cez at 4 and 6 hours after incubation . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
45,
50
]
} | {
"id": "C1335222",
"name": "1 mic",
"pos": [
117,
122
]
} |
human nucleotide sequences related to the transforming gene of a murine sarcoma virus : studies with cloned viral and cellular dnas . | organism_has_gene | {
"id": "C0086418",
"name": "human",
"pos": [
0,
5
]
} | {
"id": "C0029016",
"name": "transforming gene",
"pos": [
42,
59
]
} |
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