text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
One common feature among all these diseases is the dysentery and alteration of gut microbiota composition ( gut dysbiosis ) . | {
"id": "C0012634",
"pos": [
35,
43
],
"name": "diseases"
} | {
"id": "C0013369",
"pos": [
51,
60
],
"name": "dysentery"
} | 0NA |
The maker of lorcaserin has indicated it will continue to seek U.S. marketing approval of the drug for the indications of long-term weight loss and weight-loss maintenance in specific patient populations . | {
"id": "C0013227",
"pos": [
94,
98
],
"name": "drug"
} | {
"id": "C2350948",
"pos": [
13,
23
],
"name": "lorcaserin"
} | 0NA |
The natively easily oxidized substances such as glutathione , dopa , dopamine , serotonin , epinephrine do not interfere with the determination of ascorbic acid . | {
"id": "C0003968",
"pos": [
147,
160
],
"name": "ascorbic acid"
} | {
"id": "C0013030",
"pos": [
69,
77
],
"name": "dopamine"
} | 0NA |
This effect was more pronounced when masitinib was used as first-line therapy , with an increase in the median TTP from 75 to 253 days ( P = .001 ) and regardless of whether the tumors expressed mutant ( 83 versus not reached [ P = .009 ] ) or wild-type KIT ( 66 versus 253 [ P = .008 ] ) . | {
"id": "C0027651",
"pos": [
178,
184
],
"name": "tumors"
} | {
"id": "C0034155",
"pos": [
111,
114
],
"name": "TTP"
} | 0NA |
Pseudoaneurysms of the cervical internal carotid artery are rare and usually result from trauma , infection , or rarely spontaneously . | {
"id": "C1510412",
"pos": [
0,
15
],
"name": "Pseudoaneurysms"
} | {
"id": "C0009450",
"pos": [
98,
107
],
"name": "infection"
} | 0NA |
To stabilize the fracture , a combined dorsal and volar approach was used for open reduction and internal fixation . | {
"id": "C0016658",
"pos": [
17,
25
],
"name": "fracture"
} | {
"id": "C0016642",
"pos": [
97,
114
],
"name": "internal fixation"
} | 8direct_morphology_of |
Since arterial stiffness is a functional measure of arterial compliance and may be an important marker of cerebrovascular disease , we examined the association of carotid artery stiffness with white matter hyperintensity volume ( WMHV ) in a cross-sectional study of 1,166 stroke-free participants . | {
"id": "C0003842",
"pos": [
52,
60
],
"name": "arterial"
} | {
"id": "C0007820",
"pos": [
106,
129
],
"name": "cerebrovascular disease"
} | 0NA |
Antihypertensive ( AH ) agents have been shown to reduce the risk of major cardiovascular events including chronic heart failure ( CHF ) . | {
"id": "C0007226",
"pos": [
75,
89
],
"name": "cardiovascular"
} | {
"id": "C0264716",
"pos": [
107,
128
],
"name": "chronic heart failure"
} | 0NA |
Almost all adults have detectable antibodies if a sufficiently sensitive method is used . | {
"id": "C0003241",
"pos": [
34,
44
],
"name": "antibodies"
} | {
"id": "C0020517",
"pos": [
63,
72
],
"name": "sensitive"
} | 0NA |
Use of specific therapies , including antidotes and enhanced elimination techniques , should be limited to those cases when expectation that a defined benefit outweighs the risk of the procedure is reasonable . | {
"id": "C0184661",
"pos": [
185,
194
],
"name": "procedure"
} | {
"id": "C0087111",
"pos": [
16,
25
],
"name": "therapies"
} | 0NA |
Inclusion of garlic extract in culture medium containing glucose and xylose inhibited the hydration of rat eyelens , whereas galactose evinced the reverse trend . | {
"id": "C0017725",
"pos": [
57,
64
],
"name": "glucose"
} | {
"id": "C0043375",
"pos": [
69,
75
],
"name": "xylose"
} | 0NA |
To prospectively evaluate the effectiveness and safety of selective embolization of the uterine arteries in the management of symptomatic uterine leiomyoma . | {
"id": "C0013931",
"pos": [
68,
80
],
"name": "embolization"
} | {
"id": "C0226378",
"pos": [
88,
104
],
"name": "uterine arteries"
} | 0NA |
There were no amputations or deaths in this cohort . | {
"id": "C0011065",
"pos": [
29,
35
],
"name": "deaths"
} | {
"id": "C0002688",
"pos": [
14,
25
],
"name": "amputations"
} | 0NA |
At least three normal-appearing and mature hair follicles containing hairs were found to be growing in a coiled manner within the intrinsic musculature of the anterior two thirds of a dog 's tongue . | {
"id": "C0018494",
"pos": [
69,
74
],
"name": "hairs"
} | {
"id": "C0221971",
"pos": [
43,
57
],
"name": "hair follicles"
} | 0NA |
We aimed to evaluate the deformability characteristics of RBC and the affecting factors in newborns diagnosed with congenital hypothyroidism ( CH ) and to compare the outcomes after the L-thyroxin treatment . | {
"id": "C0010308",
"pos": [
115,
140
],
"name": "congenital hypothyroidism"
} | {
"id": "C0014772",
"pos": [
58,
61
],
"name": "RBC"
} | 0NA |
These agents did not interfere with stimulation of incorporation of D-[3 - 3H]glucose into lipid by GH ( 100 ng/ml ) or insulin ( 100 microU/ml ) but restored sensitivity to the insulin-like effects of GH in otherwise refractory cells . | {
"id": "C1292856",
"pos": [
36,
47
],
"name": "stimulation"
} | {
"id": "C0021641",
"pos": [
120,
127
],
"name": "insulin"
} | 0NA |
Treatment of cells with ambroxol did not influence bacterial attachment . | {
"id": "C0185023",
"pos": [
61,
71
],
"name": "attachment"
} | {
"id": "C0002421",
"pos": [
24,
32
],
"name": "ambroxol"
} | 0NA |
The left testis was stony hard on palpation , and intraoperative ultrasound revealed a mosaic echo pattern . | {
"id": "C0041618",
"pos": [
65,
75
],
"name": "ultrasound"
} | {
"id": "C0227998",
"pos": [
4,
15
],
"name": "left testis"
} | 0NA |
Indirect treatment comparisons of phase III clinical trials of stroke prevention in atrial fibrillation , with a focus on the secondary prevention cohorts . | {
"id": "C0199176",
"pos": [
70,
80
],
"name": "prevention"
} | {
"id": "C0038454",
"pos": [
63,
69
],
"name": "stroke"
} | 0NA |
In this article , we report on four clinical cases where a trapezius perforator flap was used either as a propeller flap , as a tunnelized island flap , or as a supercharged flap for cervical spine , thoracic spine and anterior cervical defects . | {
"id": "C0581269",
"pos": [
200,
214
],
"name": "thoracic spine"
} | {
"id": "C0038925",
"pos": [
174,
178
],
"name": "flap"
} | 0NA |
Interferons ( IFNs ) are rapidly evolving cytokines released when viral infections are detected in cells . | {
"id": "C0021747",
"pos": [
0,
11
],
"name": "Interferons"
} | {
"id": "C0042769",
"pos": [
66,
82
],
"name": "viral infections"
} | 0NA |
Arresting of enamel lesions by infiltration with light curing composite resins might be a treatment alternative of future micro-invasive dentistry . | {
"id": "C0221198",
"pos": [
20,
27
],
"name": "lesions"
} | {
"id": "C0011350",
"pos": [
13,
19
],
"name": "enamel"
} | 0NA |
Among all fetuses , MAP at 15 min of occlusion , corresponding with the time of the maximal rate of fall , was correlated with postmortem weight in males ( R(2 ) = 0.07 ) but not females . | {
"id": "C0001168",
"pos": [
37,
46
],
"name": "occlusion"
} | {
"id": "C0005910",
"pos": [
138,
144
],
"name": "weight"
} | 0NA |
Ventilatory responses ( breathing pattern and pulmonary gas exchange ) and Borg scale ratings of dyspnea and leg fatigue were measured during exercise . | {
"id": "C0013404",
"pos": [
97,
104
],
"name": "dyspnea"
} | {
"id": "C0517967",
"pos": [
24,
41
],
"name": "breathing pattern"
} | 0NA |
Examination of the medial prefrontal cortex revealed that a combination of PRX-07034 and prazosin reduced the dizocilpine-mediated increase of 5-HT . | {
"id": "C0031809",
"pos": [
0,
11
],
"name": "Examination"
} | {
"id": "C0032912",
"pos": [
89,
97
],
"name": "prazosin"
} | 0NA |
The most frequent damage observed is rhabdomyolysis syndrome , which has been mainly described after cocaine or opium consumption . | {
"id": "C0010957",
"pos": [
18,
24
],
"name": "damage"
} | {
"id": "C0009170",
"pos": [
101,
108
],
"name": "cocaine"
} | 0NA |
We conclude that bombesin and enkephalin can effect the transport of water and electrolytes in the canine jejunum . | {
"id": "C0013832",
"pos": [
79,
91
],
"name": "electrolytes"
} | {
"id": "C0043047",
"pos": [
69,
74
],
"name": "water"
} | 0NA |
The changes of the metaphysis suggested also that sCT affects the activity of hypertrophic chondrocytes of the growth plate . | {
"id": "C0020564",
"pos": [
78,
90
],
"name": "hypertrophic"
} | {
"id": "C0222671",
"pos": [
19,
29
],
"name": "metaphysis"
} | 0NA |
However , the influence of continuous , long-term HT on the relation between age , IMT , and smooth muscle dilation has not been investigated in the popliteal artery , an artery prone to stiffening and calcification . | {
"id": "C0032649",
"pos": [
149,
165
],
"name": "popliteal artery"
} | {
"id": "C0334121",
"pos": [
83,
86
],
"name": "IMT"
} | 0NA |
Unrecognized phaeochromocytoma ACTH secretion may underpin some cases of cardiovascular collapse postadrenalectomy through acute hypocortisolaemia . | {
"id": "C0007226",
"pos": [
73,
87
],
"name": "cardiovascular"
} | {
"id": "C0036974",
"pos": [
88,
96
],
"name": "collapse"
} | 0NA |
The objective of this study was to evaluate long-tailed macaques living near human communities as possible hosts of these intestinal parasites . | {
"id": "C0021853",
"pos": [
122,
132
],
"name": "intestinal"
} | {
"id": "C0475806",
"pos": [
72,
76
],
"name": "near"
} | 0NA |
Implant rehabilitation of edentulous atrophied posterior maxilla can be safely performed and simplified using the OSFE technique without grafting with reliable long-term results . | {
"id": "C0333641",
"pos": [
37,
46
],
"name": "atrophied"
} | {
"id": "C0026644",
"pos": [
26,
36
],
"name": "edentulous"
} | 0NA |
Various metal-chitosan nanocomposites were synthesized , including silver ( Ag ) , gold ( Au ) , platinum ( Pt ) , and palladium ( Pd ) in aqueous solutions . | {
"id": "C0037125",
"pos": [
67,
73
],
"name": "silver"
} | {
"id": "C0018026",
"pos": [
83,
87
],
"name": "gold"
} | 0NA |
This paper reviews the methods available to date for the determination of chlordiazepoxide , clonazepam , diazepam , flurazepam , lorazepam , nitrazepam , oxazepam and their metabolites in biological fluids . | {
"id": "C0009011",
"pos": [
93,
103
],
"name": "clonazepam"
} | {
"id": "C0012010",
"pos": [
106,
114
],
"name": "diazepam"
} | 0NA |
The use of propranolol before transplantation as prophylaxis for gastrointestinal bleeding may be considered safe , as it was not associated with worsening of cardiac index in anhepatic phase of liver transplantation . | {
"id": "C0040732",
"pos": [
30,
45
],
"name": "transplantation"
} | {
"id": "C0023911",
"pos": [
195,
216
],
"name": "liver transplantation"
} | 0NA |
Then , under stereotactic guidance , a surgical endoscopic debridement of the abscess cavity associated with the placement of an Ommaya reservoir was performed . | {
"id": "C0011334",
"pos": [
86,
92
],
"name": "cavity"
} | {
"id": "C0021107",
"pos": [
113,
122
],
"name": "placement"
} | 0NA |
These findings suggest that protective immune responses to MSP1(19 ) following immunization using oil-based Montanide ISA51 and CpG ODN as an adjuvant are very long-lasting and encourage clinical trials for malaria vaccine development . | {
"id": "C0020971",
"pos": [
79,
91
],
"name": "immunization"
} | {
"id": "C0042210",
"pos": [
215,
222
],
"name": "vaccine"
} | 0NA |
MR imaging has found abnormalities compatible with low-grade edema in the brain of patients with cirrhosis that have been related to hepatic encephalopathy . | {
"id": "C0006104",
"pos": [
74,
79
],
"name": "brain"
} | {
"id": "C0019151",
"pos": [
133,
155
],
"name": "hepatic encephalopathy"
} | 11finding_site_of |
In a randomized single-blind ( observer-blind ) clinical trial , the postoperative analgesic efficacy of diclofenac administered either as a conventional intramuscular injection ( 75 mg ) or as the available suppository formulation ( 100 mg ) was studied in 44 adult male patients undergoing herniorrhaphy in same day surgery . | {
"id": "C0031246",
"pos": [
208,
219
],
"name": "suppository"
} | {
"id": "C0012091",
"pos": [
105,
115
],
"name": "diclofenac"
} | 0NA |
The basal cell in airway epithelium plays a major role in attachment of ciliated and nonciliated columnar cells to the basal lamina . | {
"id": "C0185023",
"pos": [
58,
68
],
"name": "attachment"
} | {
"id": "C0178987",
"pos": [
18,
24
],
"name": "airway"
} | 0NA |
As an application to a realistic protein , carbon chemical shifts are calculated for the retinal chromophore in visual rhodopsin . | {
"id": "C0035298",
"pos": [
89,
96
],
"name": "retinal"
} | {
"id": "C0185125",
"pos": [
6,
17
],
"name": "application"
} | 0NA |
Lung transplantation ( LT ) is now considered to be the standard therapeutic intervention in some patients with end-stage pulmonary disease . | {
"id": "C0087111",
"pos": [
65,
89
],
"name": "therapeutic intervention"
} | {
"id": "C0024128",
"pos": [
0,
20
],
"name": "Lung transplantation"
} | 0NA |
The effects of five calcium antagonists , verapamil , diltiazem , nifedipine , darodipine and isradipine , on rat liver microsomal drug metabolism in vitro and in vivo were studied . | {
"id": "C0028066",
"pos": [
66,
76
],
"name": "nifedipine"
} | {
"id": "C0071304",
"pos": [
94,
104
],
"name": "isradipine"
} | 0NA |
Idoxuridine is not significantly bound to serum proteins and is not deiodinated in fresh serum or urine in vitro to inactive products ( iodouracil , uracil , iodide ) . | {
"id": "C0042036",
"pos": [
98,
103
],
"name": "urine"
} | {
"id": "C0020811",
"pos": [
0,
11
],
"name": "Idoxuridine"
} | 0NA |
After 5 hours of endotoxemia , lung extravascular thermal volume , postmortem bronchoalveolar lavage albumin content , and extravascular lung water/extravascular dry weight ratio of bloodless lungs were not increased , indicating no increase in alveolar-capillary permeability or pulmonary edema . | {
"id": "C0024109",
"pos": [
137,
141
],
"name": "lung"
} | {
"id": "C0034063",
"pos": [
280,
295
],
"name": "pulmonary edema"
} | 11finding_site_of |
( 3 ) The most common adverse effects with CERA were hypertension , diarrhea , headache , and upper respiratory tract infection . | {
"id": "C0020538",
"pos": [
53,
65
],
"name": "hypertension"
} | {
"id": "C0018681",
"pos": [
79,
87
],
"name": "headache"
} | 0NA |
We hypothesize that higher circulating plasma free fatty acids ( FFAs ) in metabolic syndrome inhibit the endothelial thrombomodulin (TM)-endothelial protein C receptor ( EPCR ) pathway , thereby promoting thrombus formation . | {
"id": "C0087086",
"pos": [
206,
214
],
"name": "thrombus"
} | {
"id": "C0032105",
"pos": [
39,
45
],
"name": "plasma"
} | 0NA |
The distribution of the outdoor accidents was 61.5 % for falls , 15.4 % for cuts , 15.4 % for stings and 7.7 % for burns . | {
"id": "C0006434",
"pos": [
115,
120
],
"name": "burns"
} | {
"id": "C0000921",
"pos": [
57,
62
],
"name": "falls"
} | 0NA |
These results suggest that the T score using the OC is the most relevant renal histopathological parameter associated with abnormalities of circadian blood pressure in IgAN patients . | {
"id": "C0022646",
"pos": [
73,
78
],
"name": "renal"
} | {
"id": "C0017661",
"pos": [
168,
172
],
"name": "IgAN"
} | 11finding_site_of |
It is often possible to save ovarian tissue even though the first chemotherapy courses have been undergone , but many more follicles can be stored before cancer treatment . | {
"id": "C0221971",
"pos": [
123,
132
],
"name": "follicles"
} | {
"id": "C0006826",
"pos": [
154,
160
],
"name": "cancer"
} | 0NA |
Of note , the patient 's history was positive for purpuric skin changes , suspicious for cryoglobulinemia . | {
"id": "C1446409",
"pos": [
37,
45
],
"name": "positive"
} | {
"id": "C0010403",
"pos": [
89,
105
],
"name": "cryoglobulinemia"
} | 0NA |
Insertions of CoCrMo implants are associated with a disturbance of the delicate peri-implant milieu . | {
"id": "C0441587",
"pos": [
0,
10
],
"name": "Insertions"
} | {
"id": "C0021102",
"pos": [
21,
29
],
"name": "implants"
} | 0NA |
The prevalence of diabetes mellitus was 18 % ; hypothyroidism , 16 % ; hypogonadism , 32 % ; cardiomyopathy , 9 % ; and osteopenia/osteoporosis , 83 % . | {
"id": "C0011849",
"pos": [
18,
35
],
"name": "diabetes mellitus"
} | {
"id": "C0020676",
"pos": [
47,
61
],
"name": "hypothyroidism"
} | 0NA |
Perfusion of gastrocnemius-sciatic nerve preparation of frogs with 1 microgram/ml venom solution has weakened the mechanical contraction of the muscle without recovery . | {
"id": "C0031001",
"pos": [
0,
9
],
"name": "Perfusion"
} | {
"id": "C0026845",
"pos": [
144,
150
],
"name": "muscle"
} | 0NA |
Low to moderated egg consumption was not associated with an increased CVD risk in diabetic or non-diabetic individuals at high cardiovascular risk . | {
"id": "C0007226",
"pos": [
127,
141
],
"name": "cardiovascular"
} | {
"id": "C0007222",
"pos": [
70,
73
],
"name": "CVD"
} | 11finding_site_of |
Reviparin decreased fluid-phase Bb formation detected in the lymphatic drainage of plasma-perfused hearts . | {
"id": "C0018787",
"pos": [
99,
105
],
"name": "hearts"
} | {
"id": "C0398480",
"pos": [
61,
79
],
"name": "lymphatic drainage"
} | 0NA |
Since Colon 26/IL-12 and Colon 26/IL-23 cells were also rejected in syngeneic mice , we then investigated the combinatory antitumor effects of the cytokines . | {
"id": "C0009368",
"pos": [
25,
30
],
"name": "Colon"
} | {
"id": "C0079189",
"pos": [
147,
156
],
"name": "cytokines"
} | 0NA |
Patients were switched to 1 dose of aflibercept and afterward continued their therapy with bevacizumab for at least another 6 months . | {
"id": "C0796392",
"pos": [
91,
102
],
"name": "bevacizumab"
} | {
"id": "C1134659",
"pos": [
36,
47
],
"name": "aflibercept"
} | 0NA |
The position and motion of the esophagus was considerably influenced by respiration and creation of pneumoperitoneum . | {
"id": "C0014876",
"pos": [
31,
40
],
"name": "esophagus"
} | {
"id": "C0032320",
"pos": [
100,
116
],
"name": "pneumoperitoneum"
} | 0NA |
Convulsions may occur as a consequence of insulin-induced hypoglycemia . | {
"id": "C0020615",
"pos": [
58,
70
],
"name": "hypoglycemia"
} | {
"id": "C0036572",
"pos": [
0,
11
],
"name": "Convulsions"
} | 0NA |
In this study , we investigated systematically the influence of fixation on the extraction of amyloid proteins from amyloid-containing tissue samples . | {
"id": "C0185023",
"pos": [
64,
72
],
"name": "fixation"
} | {
"id": "C0185115",
"pos": [
80,
90
],
"name": "extraction"
} | 0NA |
Postmortem examination showed the presence of a rudimentary uterus , fallopian tubes , the upper third of a vagina , a prostate of normal shape , a dilated colon , and generalized intestinal and pulmonary lymphangiectasia . | {
"id": "C0031809",
"pos": [
11,
22
],
"name": "examination"
} | {
"id": "C0004398",
"pos": [
0,
10
],
"name": "Postmortem"
} | 17method_of |
The A/B -cis , C/D-cis steroid configuration in the cardenolides , in conjunction with appropriate substituents at the 3 and 17 positions , may represent a fortuitous " fit " for the exogenous compounds . | {
"id": "C0038317",
"pos": [
23,
30
],
"name": "steroid"
} | {
"id": "C0036572",
"pos": [
169,
172
],
"name": "fit"
} | 0NA |
Preview Euthyroid hyperthyroxinemia is often misdiagnosed , resulting in inappropriate treatment with ablation or surgical removal of the thyroid gland . | {
"id": "C0547070",
"pos": [
102,
110
],
"name": "ablation"
} | {
"id": "C0040132",
"pos": [
138,
151
],
"name": "thyroid gland"
} | 0NA |
That is , F1 mice experienced in utero BPA exposure during the developmental period of reproductive organs , while F2 mice did not at all . | {
"id": "C0042149",
"pos": [
33,
38
],
"name": "utero"
} | {
"id": "C0025344",
"pos": [
77,
83
],
"name": "period"
} | 0NA |
Patients with CLL or lymphoma have been effectively treated using a non-myeloablative regimen of fludarabine/cyclophosphamide of fludarabine , cytarabine , cisplatin . | {
"id": "C0010711",
"pos": [
143,
153
],
"name": "cytarabine"
} | {
"id": "C0023434",
"pos": [
14,
17
],
"name": "CLL"
} | 0NA |
The results with estrone and progesterone were qualitatively similar but not as striking , posssibly because of the large endogenous concentrations of these two hormones . | {
"id": "C0019932",
"pos": [
161,
169
],
"name": "hormones"
} | {
"id": "C0033308",
"pos": [
29,
41
],
"name": "progesterone"
} | 0NA |
Pheochromocytoma ( PCC ) and Paraganglioma are rare tumours originating from neuroendocrine cells . | {
"id": "C0027651",
"pos": [
52,
59
],
"name": "tumours"
} | {
"id": "C0030421",
"pos": [
29,
42
],
"name": "Paraganglioma"
} | 3associated_morphology_of |
In this work , we have developed a novel fluorescent aptasensor based on single oligonucleotide-mediated isothermal quadratic amplification ( SOIQA ) and graphene oxide (GO)-mediated fluorescence quenching for the ultrasensitive detection of proteins in a homogeneous solution . | {
"id": "C0033684",
"pos": [
242,
250
],
"name": "proteins"
} | {
"id": "C0303920",
"pos": [
41,
52
],
"name": "fluorescent"
} | 0NA |
It is concluded that dermal application of a contact allergen , as exemplified by OX and HCA , may induce cell proliferation in the neighboring lymph nodes and spleen indicative of hapten and/or haptenated proteins diffusing through the skin to peripheral nodes and the blood to produce systemic sensitization . | {
"id": "C0037993",
"pos": [
160,
166
],
"name": "spleen"
} | {
"id": "C0185125",
"pos": [
28,
39
],
"name": "application"
} | 0NA |
The concept of joint barriers has been developed to differentiate among exercise therapy , mobilization , and manipulation . | {
"id": "C0022417",
"pos": [
15,
20
],
"name": "joint"
} | {
"id": "C0185112",
"pos": [
91,
103
],
"name": "mobilization"
} | 0NA |
The experimental procedures used in this study provide an assessment of renal function which involves minimal disturbance to the animal . | {
"id": "C0031809",
"pos": [
58,
68
],
"name": "assessment"
} | {
"id": "C0232804",
"pos": [
72,
86
],
"name": "renal function"
} | 0NA |
For narrow implants , the cumulative survival rate was 98.1 % in the maxilla and 96.9 % in the mandible . | {
"id": "C0021102",
"pos": [
11,
19
],
"name": "implants"
} | {
"id": "C0024687",
"pos": [
95,
103
],
"name": "mandible"
} | 0NA |
A 19-year-old woman , gravida 1 , para 0 , delivered an infant with holoprosencephaly and multiple facial and limb abnormalities at 38 weeks ' gestation . | {
"id": "C0015450",
"pos": [
99,
105
],
"name": "facial"
} | {
"id": "C0079541",
"pos": [
68,
85
],
"name": "holoprosencephaly"
} | 0NA |
In addition , the patient had an unusual form of thyroid dysfunction that was in part reversed with hydrocortisone replacement . | {
"id": "C0035139",
"pos": [
115,
126
],
"name": "replacement"
} | {
"id": "C0348024",
"pos": [
49,
68
],
"name": "thyroid dysfunction"
} | 0NA |
The defecatory function questionnaire revealed a significant improvement in constipation , urgency , bowel movements and anal eczema . | {
"id": "C0009806",
"pos": [
76,
88
],
"name": "constipation"
} | {
"id": "C0011135",
"pos": [
101,
116
],
"name": "bowel movements"
} | 15interprets |
Regarding long-term effects of ELF EMFs , reports from the former Soviet Union in the early 1960s indicated arrhythmias and tachycardia in high-voltage-switchyard workers . | {
"id": "C0003811",
"pos": [
108,
119
],
"name": "arrhythmias"
} | {
"id": "C0039231",
"pos": [
124,
135
],
"name": "tachycardia"
} | 0NA |
Data on stillbirth , neonatal/infant death , mode of delivery , gestational age at birth , Apgar score , growth outcomes , neonatal abstinence syndrome , and congenital malformations were examined . | {
"id": "C0000768",
"pos": [
158,
182
],
"name": "congenital malformations"
} | {
"id": "C0005615",
"pos": [
83,
88
],
"name": "birth"
} | 0NA |
In ischemia secondary to ipsilateral carotid stenosis , there is depression of the up-slope and a depressed and late peak . | {
"id": "C0022116",
"pos": [
3,
11
],
"name": "ischemia"
} | {
"id": "C0007282",
"pos": [
37,
53
],
"name": "carotid stenosis"
} | 0NA |
Handy media , microplates predisposed with antimalarial drug , cultured Pf parasites ( FCC-1/HN isolate ) and blood samples from patients were used to evaluate the factors influencing the in vitro determination of drug sensitivity of Pf . | {
"id": "C0003374",
"pos": [
43,
60
],
"name": "antimalarial drug"
} | {
"id": "C0237865",
"pos": [
214,
230
],
"name": "drug sensitivity"
} | 0NA |
Achalasia is a serious disorder in which the movement of food and liquids through the esophagus is impaired . | {
"id": "C0014876",
"pos": [
86,
95
],
"name": "esophagus"
} | {
"id": "C0014848",
"pos": [
0,
9
],
"name": "Achalasia"
} | 11finding_site_of |
This may be considered a feasible start point to explore the importance of B cells in the immunosuppressive MM BM microenvironment , correlating these findings with immunosenescence and therapy related increased risk of infection . | {
"id": "C0021081",
"pos": [
90,
107
],
"name": "immunosuppressive"
} | {
"id": "C0009450",
"pos": [
220,
229
],
"name": "infection"
} | 0NA |
In the laboratory , four 10-mL aliquots of saline were instilled via closed circuit suction system into a test lung with fresh hygroscopic condensers ( n = 15 ) inline . | {
"id": "C0024109",
"pos": [
111,
115
],
"name": "lung"
} | {
"id": "C0022885",
"pos": [
106,
110
],
"name": "test"
} | 0NA |
Phospholipids were extracted from lung homogenates and lavage . | {
"id": "C0024109",
"pos": [
34,
38
],
"name": "lung"
} | {
"id": "C0022100",
"pos": [
55,
61
],
"name": "lavage"
} | 0NA |
In order to develop an optimal delivery system for dipyridamole , we examined its pharmacokinetics and pharmacodynamics in human and porcine venous and arterial SMCs in vitro . | {
"id": "C0003842",
"pos": [
152,
160
],
"name": "arterial"
} | {
"id": "C0042449",
"pos": [
141,
147
],
"name": "venous"
} | 0NA |
When bone marrow transplantation was performed in a patient with AML with bone marrow from an HLA identical brother who had SLE , no evidence of transfer of disease was obtained . | {
"id": "C0005953",
"pos": [
74,
85
],
"name": "bone marrow"
} | {
"id": "C0023467",
"pos": [
65,
68
],
"name": "AML"
} | 11finding_site_of |
In all studied pts together , three multiple-regression analyses were performed with one set cystatin C as a dependent variable , in the second GFR according to the Cockcroft-Gault formula and in the third creatinine clearance by Modification of Diet in Renal Disease ( MDRD ) formula . | {
"id": "C0010294",
"pos": [
206,
216
],
"name": "creatinine"
} | {
"id": "C0022658",
"pos": [
254,
267
],
"name": "Renal Disease"
} | 0NA |
All samples showed traces of amorphous material , including magnesium and ammonium , but were negative for uric acid , cysteine , and oxalate . | {
"id": "C0024467",
"pos": [
60,
69
],
"name": "magnesium"
} | {
"id": "C0010654",
"pos": [
119,
127
],
"name": "cysteine"
} | 0NA |
The success rate for tympanic membrane integrity measured by tympanometry was 100 % at a minimum 2-year follow-up in all ears included in the study . | {
"id": "C0041445",
"pos": [
21,
38
],
"name": "tympanic membrane"
} | {
"id": "C0085853",
"pos": [
61,
73
],
"name": "tympanometry"
} | 19procedure_site_of |
Transvaginal ultrasound and serum sex steroids were used for monitoring the development of follicles . | {
"id": "C0221971",
"pos": [
91,
100
],
"name": "follicles"
} | {
"id": "C0150369",
"pos": [
61,
71
],
"name": "monitoring"
} | 0NA |
The effect of magnesium on the oxygen equilibrium was weaker than that of calcium . | {
"id": "C0024467",
"pos": [
14,
23
],
"name": "magnesium"
} | {
"id": "C0006675",
"pos": [
74,
81
],
"name": "calcium"
} | 0NA |
The risk of postoperative infection is determined by a number of factors including the underlying health of the patient , the type of surgery and the environment in which the procedure take place . | {
"id": "C0392618",
"pos": [
12,
35
],
"name": "postoperative infection"
} | {
"id": "C0543467",
"pos": [
126,
141
],
"name": "type of surgery"
} | 18occurs_after |
Shoulder dystocia poses the greatest risk for brachial plexus injury , and having a twin or multiple birth mates and delivery by cesarean section are associated with a protective effect against injury . | {
"id": "C0011209",
"pos": [
117,
125
],
"name": "delivery"
} | {
"id": "C0007876",
"pos": [
129,
145
],
"name": "cesarean section"
} | 17method_of |
The three capillaries included usual , polymer-containing , and sodium docley sulfate (SDS)-containing migration buffers for separation . | {
"id": "C0036679",
"pos": [
125,
135
],
"name": "separation"
} | {
"id": "C0006901",
"pos": [
10,
21
],
"name": "capillaries"
} | 0NA |
Statistically significant deficits were restricted to central nervous system ( CNS ) neoplasm and leukemia survivors . | {
"id": "C0027651",
"pos": [
85,
93
],
"name": "neoplasm"
} | {
"id": "C0023418",
"pos": [
98,
106
],
"name": "leukemia"
} | 0NA |
For workers such as police motorcyclists or couriers , traffic and engine noise reaching the ears is an important factor contributing to the overall condition of their work . | {
"id": "C0013443",
"pos": [
93,
97
],
"name": "ears"
} | {
"id": "C0012634",
"pos": [
149,
158
],
"name": "condition"
} | 0NA |
Brachial plexus injuries ( BPI ) are devastating events that frequently result in severe functional impairment of the upper extremity , and yet , present surgical reconstruction provides limited results . | {
"id": "C0205082",
"pos": [
82,
88
],
"name": "severe"
} | {
"id": "C0161446",
"pos": [
0,
24
],
"name": "Brachial plexus injuries"
} | 0NA |
Cells containing safranine-stained red granules were first observed in group III rats and they appeared simultaneously in hilus , medulla and cortical regions of the ovary . | {
"id": "C0029939",
"pos": [
166,
171
],
"name": "ovary"
} | {
"id": "C0025148",
"pos": [
130,
137
],
"name": "medulla"
} | 0NA |
We conducted a prospective study in 90 children measuring protein S-100 concentration in pericardial fluid directly after opening the pericardial sac before starting with cardiac surgery . | {
"id": "C0031050",
"pos": [
134,
149
],
"name": "pericardial sac"
} | {
"id": "C0031039",
"pos": [
89,
106
],
"name": "pericardial fluid"
} | 0NA |
Patients with real or perceived imperfections in particular areas of the body ( face , scalp , hands , and genital area ) are more prone to psychologic distress , whereas cutaneous diseases may lead to experience a heightened level of distress . | {
"id": "C0015450",
"pos": [
80,
84
],
"name": "face"
} | {
"id": "C0036270",
"pos": [
87,
92
],
"name": "scalp"
} | 0NA |
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