text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
Collaboration between dementia and movement disorder specialists is essential for rapid progress in research and clinical management protocols . | {
"id": "C0012634",
"pos": [
44,
52
],
"name": "disorder"
} | {
"id": "C0011265",
"pos": [
22,
30
],
"name": "dementia"
} | 0NA |
Small intestinal bacterial overgrowth syndrome ( SIBOS ) has various clinical and biological presentations . | {
"id": "C0021853",
"pos": [
6,
16
],
"name": "intestinal"
} | {
"id": "C0005750",
"pos": [
17,
46
],
"name": "bacterial overgrowth syndrome"
} | 11finding_site_of |
The first plasma itraconazole concentration , measured when the patient had been taking phenobarbital for 2 months , was very low . | {
"id": "C0032105",
"pos": [
10,
16
],
"name": "plasma"
} | {
"id": "C0031412",
"pos": [
88,
101
],
"name": "phenobarbital"
} | 0NA |
A decrease in environmental temperature by 10 degrees C appears to increase blood pressure . | {
"id": "C0005903",
"pos": [
28,
39
],
"name": "temperature"
} | {
"id": "C0005823",
"pos": [
76,
90
],
"name": "blood pressure"
} | 0NA |
Lipomas are common benign tumors . | {
"id": "C0086692",
"pos": [
19,
32
],
"name": "benign tumors"
} | {
"id": "C0023798",
"pos": [
0,
7
],
"name": "Lipomas"
} | 0NA |
Mononuclear cell infiltration of the thyroid is a prominent feature of chronic lymphocytic thyroiditis . | {
"id": "C0040132",
"pos": [
37,
44
],
"name": "thyroid"
} | {
"id": "C0677607",
"pos": [
71,
102
],
"name": "chronic lymphocytic thyroiditis"
} | 11finding_site_of |
A case of severe alcohol withdrawal complicated by seizures , hallucinosis , hypertension , and supraventricular tachycardia is presented . | {
"id": "C0020538",
"pos": [
77,
89
],
"name": "hypertension"
} | {
"id": "C0039240",
"pos": [
96,
124
],
"name": "supraventricular tachycardia"
} | 0NA |
Our results provide strong evidence that the main route for oxygen access to the active site of the enzyme follows a channel formed by transiently interconnected cavities whereby the opening and closure are governed by side chain dynamics . | {
"id": "C0185003",
"pos": [
195,
202
],
"name": "closure"
} | {
"id": "C0011334",
"pos": [
162,
170
],
"name": "cavities"
} | 0NA |
Brain tumors are the second most common neoplasm in childhood and adolescence . | {
"id": "C0027651",
"pos": [
40,
48
],
"name": "neoplasm"
} | {
"id": "C0006118",
"pos": [
0,
12
],
"name": "Brain tumors"
} | 3associated_morphology_of |
Changes of VWF structure and function might adversely affect haemostasis in APL . | {
"id": "C0042971",
"pos": [
11,
14
],
"name": "VWF"
} | {
"id": "C0019116",
"pos": [
61,
72
],
"name": "haemostasis"
} | 0NA |
The treatment of edema after a knee injury is usually 1 of the main objectives during rehabilitation . | {
"id": "C0013604",
"pos": [
17,
22
],
"name": "edema"
} | {
"id": "C0034991",
"pos": [
86,
100
],
"name": "rehabilitation"
} | 0NA |
Stroke participants made less accurate and more curved movements in VE and used less trunk displacement . | {
"id": "C0012725",
"pos": [
91,
103
],
"name": "displacement"
} | {
"id": "C0026649",
"pos": [
55,
64
],
"name": "movements"
} | 0NA |
Recovering and storing sperm from the epididymides of males of rare felidae is useful for preserving the species . | {
"id": "C0014533",
"pos": [
38,
50
],
"name": "epididymides"
} | {
"id": "C0086582",
"pos": [
54,
59
],
"name": "males"
} | 0NA |
The antibodies were also cytotoxic to B cells and this procedure gave parallel results to the fluorescence method . | {
"id": "C0184661",
"pos": [
55,
64
],
"name": "procedure"
} | {
"id": "C0003241",
"pos": [
4,
14
],
"name": "antibodies"
} | 0NA |
Nitroglycerin and phenylephrine ( 4 and 8 micrograms/kg i.v . ) were administered to 15 anesthetized mongrel dogs while monitoring blood pressure and heart rate . | {
"id": "C0017887",
"pos": [
0,
13
],
"name": "Nitroglycerin"
} | {
"id": "C0005823",
"pos": [
131,
145
],
"name": "blood pressure"
} | 0NA |
Nanophospholipid ( NPh ) formulation of doxorubicin was prepared by homogenization of soybean phosphatidylcholine and doxorubicin hydrochloride . | {
"id": "C0546861",
"pos": [
118,
143
],
"name": "doxorubicin hydrochloride"
} | {
"id": "C0013089",
"pos": [
40,
51
],
"name": "doxorubicin"
} | 16is_modification_of |
Ethically , it must be assumed that cognitively impaired elders will benefit from some form of crisis intervention prior to nursing home relocation . | {
"id": "C0231224",
"pos": [
95,
101
],
"name": "crisis"
} | {
"id": "C0184661",
"pos": [
102,
114
],
"name": "intervention"
} | 0NA |
Treatment includes early airway and ventilatory support as well as antidotal therapy with atropine , pralidoxime , and diazepam . | {
"id": "C0071808",
"pos": [
101,
112
],
"name": "pralidoxime"
} | {
"id": "C0004259",
"pos": [
90,
98
],
"name": "atropine"
} | 0NA |
Early temporary closure of the abdominal wall using BB in patients with abdominal sepsis and planned re-explorations is simple , safe , inexpensive , and effective . | {
"id": "C0185003",
"pos": [
16,
23
],
"name": "closure"
} | {
"id": "C0836916",
"pos": [
31,
45
],
"name": "abdominal wall"
} | 0NA |
The aim of this study was to evaluate the odds ratio ( OR ) of joints with disc displacement presenting osteoarthrosis via magnetic resonance imaging ( MRI ) analysis . | {
"id": "C0022417",
"pos": [
63,
69
],
"name": "joints"
} | {
"id": "C0029408",
"pos": [
104,
118
],
"name": "osteoarthrosis"
} | 11finding_site_of |
Calcium , magnesium , phosphate , oxalate , and uric acid levels in the urine were measured . | {
"id": "C0024467",
"pos": [
10,
19
],
"name": "magnesium"
} | {
"id": "C0006675",
"pos": [
0,
7
],
"name": "Calcium"
} | 0NA |
Angioedema , the rapid swelling of under-skin tissue , is typically triggered by complex biochemical processes that disrupt an original steady state filtration of liquid through the tissue . | {
"id": "C0013604",
"pos": [
23,
31
],
"name": "swelling"
} | {
"id": "C0040300",
"pos": [
182,
188
],
"name": "tissue"
} | 0NA |
Therefore , we investigated APOE genotypes of shingles , PHN , and IM patients . | {
"id": "C0032768",
"pos": [
57,
60
],
"name": "PHN"
} | {
"id": "C0019360",
"pos": [
46,
54
],
"name": "shingles"
} | 18occurs_after |
The forensic doctor can intervene where a body is discovered , and the aim of the autopsy is to check if burns were the cause of death . | {
"id": "C0006434",
"pos": [
105,
110
],
"name": "burns"
} | {
"id": "C0004398",
"pos": [
82,
89
],
"name": "autopsy"
} | 0NA |
It is also shown that the decision-making system in reply to emotion includes vector component which seems to be often a necessary condition to transfer system from one state to another . | {
"id": "C0012634",
"pos": [
131,
140
],
"name": "condition"
} | {
"id": "C0013987",
"pos": [
61,
68
],
"name": "emotion"
} | 0NA |
Persistence of the internal tract is a condition at higher risk of fistula recurrence . | {
"id": "C0016169",
"pos": [
67,
74
],
"name": "fistula"
} | {
"id": "C0012634",
"pos": [
39,
48
],
"name": "condition"
} | 0NA |
The mutant cells showed irregular shapes with swelling and were also hypersensitive to Zymolyase digestion . | {
"id": "C0013604",
"pos": [
46,
54
],
"name": "swelling"
} | {
"id": "C0020517",
"pos": [
69,
83
],
"name": "hypersensitive"
} | 0NA |
Using a newly established monoclonal antibody , we found that calnexin is regularly synthesized by Paneth cells of normal small intestine . | {
"id": "C0021853",
"pos": [
128,
137
],
"name": "intestine"
} | {
"id": "C0003250",
"pos": [
26,
45
],
"name": "monoclonal antibody"
} | 0NA |
p52/p36-deficient parasites exhibited normal progression through the life cycle during blood-stage infection , transmission to mosquitoes , mosquito-stage development , and sporozoite infection of the salivary glands . | {
"id": "C0009450",
"pos": [
184,
193
],
"name": "infection"
} | {
"id": "C0036098",
"pos": [
201,
216
],
"name": "salivary glands"
} | 0NA |
Metals accumulation ( Rb , Al , Se , Sr , Tl , Ce , Co , Cu , Pb ) effects of both waterborne and multi-trophic exposures were significant in one or more fathead minnow tissue type ( muscle , gonads , liver , larvae ) relative to those in the control systems . | {
"id": "C0023884",
"pos": [
201,
206
],
"name": "liver"
} | {
"id": "C0018067",
"pos": [
192,
198
],
"name": "gonads"
} | 0NA |
The final pathological conclusion was sclerosing hemangioma of the lung . | {
"id": "C0024109",
"pos": [
67,
71
],
"name": "lung"
} | {
"id": "C0002991",
"pos": [
38,
59
],
"name": "sclerosing hemangioma"
} | 0NA |
However , the amount of walking completed by individuals with stroke attending rehabilitation is far below that required for independent community ambulation . | {
"id": "C0034991",
"pos": [
79,
93
],
"name": "rehabilitation"
} | {
"id": "C0038454",
"pos": [
62,
68
],
"name": "stroke"
} | 0NA |
We report a 42-year old woman with myocardial infarction and venous thrombosis in whom recognition of heterozygous MTHRF gene mutation , hyperhomocysteinemia , and protein C deficiency . | {
"id": "C0042487",
"pos": [
61,
78
],
"name": "venous thrombosis"
} | {
"id": "C0027051",
"pos": [
35,
56
],
"name": "myocardial infarction"
} | 0NA |
In conclusion , R-fadrozole may possess considerable therapeutic merit because of its potent antifibrotic actions in the heart . | {
"id": "C0018787",
"pos": [
121,
126
],
"name": "heart"
} | {
"id": "C0087111",
"pos": [
53,
64
],
"name": "therapeutic"
} | 0NA |
These results indicate strongly that X and Y cells inform the cat 's brain about contrast in the retinal image . | {
"id": "C0006104",
"pos": [
69,
74
],
"name": "brain"
} | {
"id": "C0035298",
"pos": [
97,
104
],
"name": "retinal"
} | 0NA |
To determine the relation between depressive symptoms and seizure severity among people with epilepsy . | {
"id": "C0086132",
"pos": [
34,
53
],
"name": "depressive symptoms"
} | {
"id": "C0036572",
"pos": [
58,
65
],
"name": "seizure"
} | 0NA |
Overall , 6.5 % , 17.7 % and 14.0 % of participants reported that they had been diagnosed with diabetes mellitus , hypertension and hypercholesterolemia , respectively . | {
"id": "C0011849",
"pos": [
95,
112
],
"name": "diabetes mellitus"
} | {
"id": "C0020538",
"pos": [
115,
127
],
"name": "hypertension"
} | 0NA |
At the age of 69 years , multiple soft , violaceous to dark-red patches , plaques , nodules and blisters of varying sizes appeared on a background of severely edematous skin on her legs , and later on her arms . | {
"id": "C0005758",
"pos": [
96,
104
],
"name": "blisters"
} | {
"id": "C0206655",
"pos": [
205,
209
],
"name": "arms"
} | 0NA |
Asthma and allergy are the most common diseases associated with cockroach infestation of houses in the United States and other parts of the world . | {
"id": "C0030499",
"pos": [
74,
85
],
"name": "infestation"
} | {
"id": "C0012634",
"pos": [
39,
47
],
"name": "diseases"
} | 0NA |
A phantom consisting of a gel closely resembling human liver on B-mode scanning , and containing a rounded zone of decreased echogenicity , was used to create a series of B-mode ultrasonic images containing simulated " lesions " in random locations on the final recorded image . | {
"id": "C0221198",
"pos": [
219,
226
],
"name": "lesions"
} | {
"id": "C0023884",
"pos": [
55,
60
],
"name": "liver"
} | 0NA |
A microscopic examination showed fibric membrane of the mass and numerous vascular channels surrounded by proliferated smooth muscle . | {
"id": "C0577559",
"pos": [
56,
60
],
"name": "mass"
} | {
"id": "C0026018",
"pos": [
2,
25
],
"name": "microscopic examination"
} | 0NA |
Although the clinical value needs further investigations , PRS IR seems to be effective in metastases while it provides less benefit in malignant gliomas . | {
"id": "C0555198",
"pos": [
136,
153
],
"name": "malignant gliomas"
} | {
"id": "C1261322",
"pos": [
42,
56
],
"name": "investigations"
} | 0NA |
We present a case whereby the latter mechanical stresses may have contributed to the fracture of a stent implanted in the saphenous vein graft to the right coronary artery . | {
"id": "C0016658",
"pos": [
85,
93
],
"name": "fracture"
} | {
"id": "C0729538",
"pos": [
122,
142
],
"name": "saphenous vein graft"
} | 0NA |
The I/R hearts tissue were harvested to evaluate apoptosis ratio with TUNEL assay and protein expression with western blot . | {
"id": "C0018787",
"pos": [
8,
14
],
"name": "hearts"
} | {
"id": "C0040300",
"pos": [
15,
21
],
"name": "tissue"
} | 0NA |
Light and electron microscopy made it possible to diagnose the dystrophic form of the disease and the clinical course confirmed the indication of surgical treatment . | {
"id": "C0012634",
"pos": [
86,
93
],
"name": "disease"
} | {
"id": "C0543467",
"pos": [
146,
164
],
"name": "surgical treatment"
} | 0NA |
Although both types of autoimmunity are ' paraneoplastic ' , as indirectly triggered by the presence of a tumor , they profoundly differ in terms of clinical profile , pathogenesis and outcome . | {
"id": "C0027651",
"pos": [
106,
111
],
"name": "tumor"
} | {
"id": "C0004364",
"pos": [
23,
35
],
"name": "autoimmunity"
} | 0NA |
Lung cancer is among the tumor entities with the highest incidence and mortality rates . | {
"id": "C0027651",
"pos": [
25,
30
],
"name": "tumor"
} | {
"id": "C0242379",
"pos": [
0,
11
],
"name": "Lung cancer"
} | 0NA |
Noradrenaline concentration increased only after the lowest dose of the drug . | {
"id": "C0013227",
"pos": [
72,
76
],
"name": "drug"
} | {
"id": "C0028351",
"pos": [
0,
13
],
"name": "Noradrenaline"
} | 0NA |
The presence of autoantibodies ( ICA , GADA , anti-IA2 , IAA ) in serum precedes the clinical onset of the disease . | {
"id": "C0004358",
"pos": [
16,
30
],
"name": "autoantibodies"
} | {
"id": "C0201519",
"pos": [
33,
36
],
"name": "ICA"
} | 6component_of |
Azilsartan medoxomil is a newly approved angiotensin receptor blocker ( ARB ) reported to lower 24-h blood pressure more effectively than maximally recommended doses of older ARBs . | {
"id": "C1958569",
"pos": [
0,
10
],
"name": "Azilsartan"
} | {
"id": "C0005823",
"pos": [
101,
115
],
"name": "blood pressure"
} | 0NA |
All patients were included in a national multicenter study on the effect of adjuvant tamoxifen treatment in hormone sensitive breast cancer , i.e. estrogen receptor content of at least 10 pmol/g cytosol protein . | {
"id": "C0019932",
"pos": [
108,
115
],
"name": "hormone"
} | {
"id": "C0020517",
"pos": [
116,
125
],
"name": "sensitive"
} | 0NA |
In vitro tests compared the two new drugs with five other antimicrobial agents against 216 gram-positive isolates representing 4 genera and 10 species . | {
"id": "C0013227",
"pos": [
36,
41
],
"name": "drugs"
} | {
"id": "C1136254",
"pos": [
58,
78
],
"name": "antimicrobial agents"
} | 0NA |
We aimed to estimate the association between first-trimester maximum placental thickness and the subsequent risk of preeclampsia and/or the delivery of small-for-gestational-age ( SGA ) neonate . | {
"id": "C0011209",
"pos": [
140,
148
],
"name": "delivery"
} | {
"id": "C0032914",
"pos": [
116,
128
],
"name": "preeclampsia"
} | 0NA |
When rat hepatocytes were cultured on Matrigel and exposed to dexamethasone ( Dex ) , steady state levels of 3alpha-HSD/DD mRNA were increased 4-fold in a dose-dependent manner , yielding an EC50 value of 10 nM. Time to maximal response was 24 hr , and the effect was blocked with the anti-glucocorticoid RU486 . | {
"id": "C0028778",
"pos": [
268,
275
],
"name": "blocked"
} | {
"id": "C0011777",
"pos": [
62,
75
],
"name": "dexamethasone"
} | 0NA |
The success rates of angioplasty and the subsequent revascularization requirements in these two angina categories were compared during a one year prospective follow-up . | {
"id": "C0581603",
"pos": [
52,
69
],
"name": "revascularization"
} | {
"id": "C0002962",
"pos": [
96,
102
],
"name": "angina"
} | 0NA |
A 5-mm defect , stabilized by a plate , was created in the femurs of 30 male Wistar rats . | {
"id": "C0015811",
"pos": [
59,
65
],
"name": "femurs"
} | {
"id": "C0005971",
"pos": [
32,
37
],
"name": "plate"
} | 0NA |
These data support the idea that the self-injection of apomorphine is produced via the direct activation of dopamine receptors rather than by the release of either norepinephrine or dopamine . | {
"id": "C0003596",
"pos": [
55,
66
],
"name": "apomorphine"
} | {
"id": "C0028351",
"pos": [
164,
178
],
"name": "norepinephrine"
} | 0NA |
Prospective , comparative , randomized long-term studies are necessary to determine the cause(s ) of loosening of prostheses with this particular articulation . | {
"id": "C0022417",
"pos": [
146,
158
],
"name": "articulation"
} | {
"id": "C0175649",
"pos": [
114,
124
],
"name": "prostheses"
} | 0NA |
These intestinal lesions were not considered to be of sufficient severity to cause mortality and , thus , in the p53(+/- ) mouse 40-week study , the high dose of 10,000 ppm was selected . | {
"id": "C0221198",
"pos": [
17,
24
],
"name": "lesions"
} | {
"id": "C0021853",
"pos": [
6,
16
],
"name": "intestinal"
} | 0NA |
Physicochemical stability was evaluated under accelerated aging ( high temperature and UV light exposure ) , as well as during simulated gastrointestinal digestion . | {
"id": "C0001811",
"pos": [
58,
63
],
"name": "aging"
} | {
"id": "C0005903",
"pos": [
71,
82
],
"name": "temperature"
} | 0NA |
Among the causes of death of thorotrast carriers in the ( old ) Federal Republic of Germany , 15 % are attributed to primary hepatic tumours ( cholangiocarcinomas , malignant haemangioendotheliomas , hepatic cell carcinomas ) . | {
"id": "C0007294",
"pos": [
40,
48
],
"name": "carriers"
} | {
"id": "C0206698",
"pos": [
143,
162
],
"name": "cholangiocarcinomas"
} | 0NA |
Surgical patients with a history of cerebrovascular disease should be evaluated by a neurologist . | {
"id": "C0007820",
"pos": [
36,
59
],
"name": "cerebrovascular disease"
} | {
"id": "C0543467",
"pos": [
0,
8
],
"name": "Surgical"
} | 0NA |
BACKGROUND Total artificial heart ( TAH ) implantation in patients with aggressive tumor infiltration of the heart can be challenging . | {
"id": "C0018787",
"pos": [
109,
114
],
"name": "heart"
} | {
"id": "C0021107",
"pos": [
42,
54
],
"name": "implantation"
} | 0NA |
An examination was performed on the corneal aberrometry in the anterior corneal surface , and topographic mapping ( by Amsler and Muckenhirn classification ) was used to determine the degree of keratoconus . | {
"id": "C0010031",
"pos": [
72,
79
],
"name": "corneal"
} | {
"id": "C0022578",
"pos": [
194,
205
],
"name": "keratoconus"
} | 11finding_site_of |
However , 12 of 71 patients with amenorrhea longer than 2 years ( 17 % ) had detectable tumors and the risk appears to increase progressively with time . | {
"id": "C0027651",
"pos": [
88,
94
],
"name": "tumors"
} | {
"id": "C0002453",
"pos": [
33,
43
],
"name": "amenorrhea"
} | 0NA |
Of 296 SLE patients , 33 with a vascular event prior to baseline were excluded . | {
"id": "C0005847",
"pos": [
32,
40
],
"name": "vascular"
} | {
"id": "C0014060",
"pos": [
7,
10
],
"name": "SLE"
} | 0NA |
All treatments were well tolerated with the percentage of patients reporting treatment-related adverse experiences at any time ranging from 9.9 % ( valsartan 160 mg ) to 21.0 % ( HCTZ 25 mg combination ) . | {
"id": "C0020261",
"pos": [
179,
183
],
"name": "HCTZ"
} | {
"id": "C0216784",
"pos": [
148,
157
],
"name": "valsartan"
} | 0NA |
Until recently , differently from most adult tumors , only limited information was available on the methylation aberrations in neuroblastoma . | {
"id": "C0027651",
"pos": [
45,
51
],
"name": "tumors"
} | {
"id": "C0027819",
"pos": [
127,
140
],
"name": "neuroblastoma"
} | 0NA |
This study aimed at evaluating the efficacy and safety of epirubicin , oxaliplatin , and capecitabine ( EOX ) in advanced gastric cancer ( AGC ) patients in the Chinese population . | {
"id": "C0069717",
"pos": [
71,
82
],
"name": "oxaliplatin"
} | {
"id": "C0671970",
"pos": [
89,
101
],
"name": "capecitabine"
} | 0NA |
Lysine vasopressin ( 5.2 and 10.4 microM ) failed to significantly alter the spontaneous release of (3H)-noradrenaline from hippocampal slices in vitro or the release observed after stimulation with potassium chloride ( 15 and 25 mM ) . | {
"id": "C1292856",
"pos": [
182,
193
],
"name": "stimulation"
} | {
"id": "C0032825",
"pos": [
199,
217
],
"name": "potassium chloride"
} | 0NA |
Hyperglycemia is a major if not sole determinant of diabetic glomerulopathy . | {
"id": "C0020456",
"pos": [
0,
13
],
"name": "Hyperglycemia"
} | {
"id": "C0017667",
"pos": [
52,
75
],
"name": "diabetic glomerulopathy"
} | 0NA |
We proposed this study to evaluate the prevalence of cardiotoxicity associated with bortezomib and its relation to multiple myeloma and other malignancies . | {
"id": "C1176309",
"pos": [
84,
94
],
"name": "bortezomib"
} | {
"id": "C0006826",
"pos": [
142,
154
],
"name": "malignancies"
} | 0NA |
These included parastomal hernia ( p < 0.001 ) , stenosis ( p = 0.003 ) , and prolapse ( p = 0.008 ) . | {
"id": "C0033377",
"pos": [
78,
86
],
"name": "prolapse"
} | {
"id": "C0341539",
"pos": [
15,
32
],
"name": "parastomal hernia"
} | 0NA |
The severity of injury depends on the temperature , duration of exposure , and amount and depth of frozen tissue . | {
"id": "C3263722",
"pos": [
16,
22
],
"name": "injury"
} | {
"id": "C0005903",
"pos": [
38,
49
],
"name": "temperature"
} | 0NA |
This is based on the pivotal role that atherosclerotic plaque plays in the natural history of cardiovascular disease and the acceptance of validated arterial imaging approaches including coronary angiography and carotid intimal-medial thickness by regulatory authorities . | {
"id": "C0085532",
"pos": [
187,
207
],
"name": "coronary angiography"
} | {
"id": "C0011389",
"pos": [
55,
61
],
"name": "plaque"
} | 0NA |
Renal histopathology revealed membranoproliferative glomerulonephritis , along with a full house pattern on IFF consistent with lupus nephritis . | {
"id": "C0022646",
"pos": [
0,
5
],
"name": "Renal"
} | {
"id": "C0024143",
"pos": [
128,
143
],
"name": "lupus nephritis"
} | 0NA |
Investigations of more detailed physiologic phenotypes , such as the insulin response to intravenous glucose or the incretion hormones , are now emerging and give indications of more specific pathologic mechanisms for diabetes-related risk variants . | {
"id": "C0031437",
"pos": [
44,
54
],
"name": "phenotypes"
} | {
"id": "C1261322",
"pos": [
0,
14
],
"name": "Investigations"
} | 0NA |
To elucidate whether MRI can detect fat in interstitial histiocytes and hemosiderin ( Hs ) deposition ( both of which are histological characteristics of papillary renal carcinoma ( RCpap ) ) within RCpap . | {
"id": "C0024485",
"pos": [
21,
24
],
"name": "MRI"
} | {
"id": "C0015677",
"pos": [
36,
39
],
"name": "fat"
} | 0NA |
The perianal area and anal canal were then examined using a colposcope , and areas macroscopically suggestive of intraepithelial neoplasia were biopsied . | {
"id": "C0005558",
"pos": [
144,
152
],
"name": "biopsied"
} | {
"id": "C0180030",
"pos": [
60,
70
],
"name": "colposcope"
} | 0NA |
Acute cholecystitis is one of the most frequent diseases occurring in developed countries of the world . | {
"id": "C0012634",
"pos": [
48,
56
],
"name": "diseases"
} | {
"id": "C0149520",
"pos": [
0,
19
],
"name": "Acute cholecystitis"
} | 0NA |
We present two cases of microphthalmos with cyst affecting monozygotic twins . | {
"id": "C0010709",
"pos": [
44,
48
],
"name": "cyst"
} | {
"id": "C0026010",
"pos": [
24,
38
],
"name": "microphthalmos"
} | 0NA |
Increased myocardial synthesis of active AM may protect against cardiac dysfunction , myocardial remodeling , or both after the onset of AMI . | {
"id": "C0027061",
"pos": [
10,
20
],
"name": "myocardial"
} | {
"id": "C0027051",
"pos": [
137,
140
],
"name": "AMI"
} | 11finding_site_of |
Recent observations have shown that hyaluronan ( HA ) is an important inhibitor of inflammation . | {
"id": "C0021368",
"pos": [
83,
95
],
"name": "inflammation"
} | {
"id": "C0020196",
"pos": [
36,
46
],
"name": "hyaluronan"
} | 0NA |
In patients with active pulmonary tuberculosis activities of acid and alkaline phosphatases were altered in leukocytes and the activity of NAD-glycohydrolase -- in erythrocytes . | {
"id": "C0001128",
"pos": [
61,
65
],
"name": "acid"
} | {
"id": "C0014772",
"pos": [
164,
176
],
"name": "erythrocytes"
} | 0NA |
Race was significantly associated with blood pressure > or = 140/90 when controlled for age and overweight ( p = 0.01 , OR = 0.78 , CI = 0.69 - 0.95 ) . | {
"id": "C0497406",
"pos": [
96,
106
],
"name": "overweight"
} | {
"id": "C0005823",
"pos": [
39,
53
],
"name": "blood pressure"
} | 0NA |
Pancuronium(bromide ) is used because of its relaxing effect on striated muscles and usually requires artificial respiration . | {
"id": "C0242692",
"pos": [
64,
80
],
"name": "striated muscles"
} | {
"id": "C0035203",
"pos": [
113,
124
],
"name": "respiration"
} | 0NA |
Important in the postoperative management of neonates with single-ventricle complexes , such as hypoplastic left heart syndrome and pulmonary atresia with intact ventricular septum , is the fact that the pulmonary circulation is connected to the systemic circulation via a shunt . | {
"id": "C0225870",
"pos": [
162,
180
],
"name": "ventricular septum"
} | {
"id": "C0242855",
"pos": [
132,
149
],
"name": "pulmonary atresia"
} | 0NA |
While obesity has been linked closely with type 2 diabetes mellitus and hypertension , reduced insulin sensitivity is a direct mechanism for renal damage . | {
"id": "C0011860",
"pos": [
43,
67
],
"name": "type 2 diabetes mellitus"
} | {
"id": "C0020517",
"pos": [
103,
114
],
"name": "sensitivity"
} | 0NA |
Our results demonstrate the potent activity of cidofovir against tumors that are not associated with a virus . | {
"id": "C0027651",
"pos": [
65,
71
],
"name": "tumors"
} | {
"id": "C0286079",
"pos": [
47,
56
],
"name": "cidofovir"
} | 0NA |
Gradient operation of a simulated moving bed ( SMB ) can improve the separation and purification performance by adjusting adsorption strength in each individual zone according to its functional role . | {
"id": "C0036679",
"pos": [
69,
79
],
"name": "separation"
} | {
"id": "C0543467",
"pos": [
9,
18
],
"name": "operation"
} | 0NA |
Tumors diagnosed during pregnancy had higher expression of PD1 ( PDCD1 ; P=0.015 ) , PDL1 ( CD274 ; P=0.014 ) , and gene sets related to SRC ( P=0.004 ) , IGF1 ( P=0.032 ) , and β-catenin ( P=0.019 ) . | {
"id": "C0027651",
"pos": [
0,
6
],
"name": "Tumors"
} | {
"id": "C0202220",
"pos": [
155,
159
],
"name": "IGF1"
} | 0NA |
CTGF and integrin αvβ6 proteins were highly expressed in DRs of human cirrhotic livers and cholangiocarcinoma . | {
"id": "C0023884",
"pos": [
80,
86
],
"name": "livers"
} | {
"id": "C0206698",
"pos": [
91,
109
],
"name": "cholangiocarcinoma"
} | 0NA |
Prostate cancer is the most commonly diagnosed cancer in American men and a major health problem . | {
"id": "C0006826",
"pos": [
47,
53
],
"name": "cancer"
} | {
"id": "C0376358",
"pos": [
0,
15
],
"name": "Prostate cancer"
} | 0NA |
MTT , electron microscopy and TUNEL assay were used to identify cell viability and apoptosis in neonatal mice cardiac fibroblasts . | {
"id": "C0018787",
"pos": [
110,
117
],
"name": "cardiac"
} | {
"id": "C0026019",
"pos": [
6,
25
],
"name": "electron microscopy"
} | 0NA |
Then , we applied R language software and developed an interactive shared and updated database ( dbMDEGA ) displaying the results of meta-analysis of data from ASD studies regarding differentially expressed genes ( DEGs ) in the brain . | {
"id": "C0006104",
"pos": [
229,
234
],
"name": "brain"
} | {
"id": "C0018817",
"pos": [
160,
163
],
"name": "ASD"
} | 0NA |
For the removal mechanism , Fourier transform infrared spectroscopy revealed that carboxyl , amido and hydroxyl of saccharides , and proteins in the extracellular polymeric substances are the most active groups for Cd(II ) absorption . | {
"id": "C0015252",
"pos": [
8,
15
],
"name": "removal"
} | {
"id": "C0007004",
"pos": [
115,
126
],
"name": "saccharides"
} | 0NA |
Modern electroceuticals are bound to employ the usage of electrical high frequency ( 130 - 180 Hz ) stimulation carried out under closed loop control , most prominent in the case of movement disorders . | {
"id": "C1292856",
"pos": [
100,
111
],
"name": "stimulation"
} | {
"id": "C0026650",
"pos": [
182,
200
],
"name": "movement disorders"
} | 0NA |
Therefore , salivary components have potential in the development of new drugs or genetically engineered mosquitoes for malaria control . | {
"id": "C0013227",
"pos": [
73,
78
],
"name": "drugs"
} | {
"id": "C0024530",
"pos": [
120,
127
],
"name": "malaria"
} | 0NA |
Current pharmacological treatment widely used for AD and dementia , including cholinesterase inhibitors ( donepezil , rivastigmine , and galantamine ) and the N-methyl-D-aspartate-receptor antagonist ( memantine ) , psychotropic medications are designed to target clinical symptoms of the disease such as cognitive and neuropsychiatric disturbances . | {
"id": "C0012634",
"pos": [
289,
296
],
"name": "disease"
} | {
"id": "C0011265",
"pos": [
57,
65
],
"name": "dementia"
} | 0NA |
Total incontinence , that is , the continuous loss of urine as opposed to the loss associated with coughing or sneezing , is the most severe type of the malady . | {
"id": "C0205082",
"pos": [
134,
140
],
"name": "severe"
} | {
"id": "C0037383",
"pos": [
111,
119
],
"name": "sneezing"
} | 0NA |
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