text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
The antibiotic vancomycin has been available since the 1950s but has been used more commonly since the early 1980s because of the widespread appearance of methicillin-resistant Staphylococcus aureus . | {
"id": "C0042313",
"pos": [
15,
25
],
"name": "vancomycin"
} | {
"id": "C0343401",
"pos": [
155,
198
],
"name": "methicillin-resistant Staphylococcus aureus"
} | 0NA |
The most widely used aromatase inhibitor has been aminoglutethimide ; however , it is nonselective and also inhibits adrenocorticosteroid synthesis , necessitating hydrocortisone supplementation . | {
"id": "C0020268",
"pos": [
164,
178
],
"name": "hydrocortisone"
} | {
"id": "C0002555",
"pos": [
50,
67
],
"name": "aminoglutethimide"
} | 0NA |
Ignorance in mice can be broken by immunization with DCs coated with TELEISSI , a peptide derived from the N protein of BDV , which represents the immunodominant cytotoxic T lymphocyte epitope in H-2(k ) mice . | {
"id": "C0020971",
"pos": [
35,
47
],
"name": "immunization"
} | {
"id": "C0010590",
"pos": [
53,
56
],
"name": "DCs"
} | 0NA |
Pasteurella multocida is a Gram-negative multispecies pathogen and the causative agent of fowl cholera , a serious disease of poultry which can present in both acute and chronic forms . | {
"id": "C0012634",
"pos": [
115,
122
],
"name": "disease"
} | {
"id": "C0008354",
"pos": [
95,
102
],
"name": "cholera"
} | 0NA |
Rat models of liver fibrosis/cirrhosis were induced by intraperitoneal administration of dimethylnitrosamine , followed by 45 % partial hepatectomy or sham operation . | {
"id": "C0019144",
"pos": [
136,
147
],
"name": "hepatectomy"
} | {
"id": "C0543467",
"pos": [
156,
165
],
"name": "operation"
} | 0NA |
A rapid thoracotomy permits the extraction of the compressed lung and the resuscitation of the patient . | {
"id": "C0024109",
"pos": [
61,
65
],
"name": "lung"
} | {
"id": "C0185115",
"pos": [
32,
42
],
"name": "extraction"
} | 0NA |
The study design involved the measurement of ovarian steroids and FSH in urine collected daily during a period of time when animals experienced a well-defined event on two occasions consisting of capture , restraint , and anesthesia . | {
"id": "C0035260",
"pos": [
206,
215
],
"name": "restraint"
} | {
"id": "C0002903",
"pos": [
222,
232
],
"name": "anesthesia"
} | 0NA |
Five children between 4 and 6 years of age with unilateral cataract had cataract extraction and implantation of an apodized diffractive multifocal IOL ( AcrySof Restor SN60D3 ) . | {
"id": "C0086543",
"pos": [
59,
67
],
"name": "cataract"
} | {
"id": "C0007389",
"pos": [
72,
91
],
"name": "cataract extraction"
} | 8direct_morphology_of |
Diagnostic tests based mainly on cytological studies do not make it possible to detect early changes of the proliferation process in the cells of the urinary bladder epithelium . | {
"id": "C0005682",
"pos": [
150,
165
],
"name": "urinary bladder"
} | {
"id": "C0014609",
"pos": [
166,
176
],
"name": "epithelium"
} | 0NA |
In Type 2 diabetes , factors that contribute to excessive postprandial glucose excursions include disruption of insulin secretion , insufficient inhibition of hepatic glucose production and defective glucose storage in muscle . | {
"id": "C0026845",
"pos": [
219,
225
],
"name": "muscle"
} | {
"id": "C0011860",
"pos": [
3,
18
],
"name": "Type 2 diabetes"
} | 0NA |
Colon ALP was correlated with mucins , caecal n-butyrate and faecal Bifidobacterium spp . | {
"id": "C0015733",
"pos": [
61,
67
],
"name": "faecal"
} | {
"id": "C0009368",
"pos": [
0,
5
],
"name": "Colon"
} | 0NA |
The effects of ECT and ketamine on cortical activity during cognitive tasks will be studied in a sub-sample using functional near-infrared spectroscopy ( fNIRS ) . | {
"id": "C0013806",
"pos": [
15,
18
],
"name": "ECT"
} | {
"id": "C0022614",
"pos": [
23,
31
],
"name": "ketamine"
} | 0NA |
Negative bias and a proportional systematic error were apparent for PLT count , feline HCT , and eosinophil count . | {
"id": "C0205160",
"pos": [
0,
8
],
"name": "Negative"
} | {
"id": "C0200638",
"pos": [
97,
113
],
"name": "eosinophil count"
} | 0NA |
Endovascular therapy may be a more suitable recanalization strategy for some patients with cancer and stroke , but no prior detailed reports documenting its use in this population exist . | {
"id": "C0038454",
"pos": [
102,
108
],
"name": "stroke"
} | {
"id": "C0006826",
"pos": [
91,
97
],
"name": "cancer"
} | 0NA |
The most important strategy for treatment is to observe the moment of breastfeeding and give individual advice ( the procedure is described ) . | {
"id": "C0150600",
"pos": [
104,
110
],
"name": "advice"
} | {
"id": "C0184661",
"pos": [
117,
126
],
"name": "procedure"
} | 0NA |
The regeneration of nerve is a brilliant example of plasticity within the nervous system . | {
"id": "C0027763",
"pos": [
74,
88
],
"name": "nervous system"
} | {
"id": "C0027740",
"pos": [
20,
25
],
"name": "nerve"
} | 0NA |
Several possibilities have been also described for clinically adapting this method in the rehabilitation of the shoulder and knee and postoperative improvement of tendons . | {
"id": "C0037004",
"pos": [
112,
120
],
"name": "shoulder"
} | {
"id": "C0022742",
"pos": [
125,
129
],
"name": "knee"
} | 0NA |
The inhibitory effect of iRGD MTX ICG ELIP combined with ultrasound on synovial MH7A cells in vitro were investigated using CCK8 test . | {
"id": "C0041618",
"pos": [
57,
67
],
"name": "ultrasound"
} | {
"id": "C0025677",
"pos": [
30,
33
],
"name": "MTX"
} | 0NA |
Patients with TMD most commonly present with pain , restricted or asymmetric mandibular motion , and TMJ sounds during mandibular movements . | {
"id": "C0039493",
"pos": [
101,
104
],
"name": "TMJ"
} | {
"id": "C0039494",
"pos": [
14,
17
],
"name": "TMD"
} | 11finding_site_of |
On crossed immunoelectrophoresis , the abnormal prothrombin peaks with reduced electrophoretic mobilities were considered prothrombin/prothrombin-antibody complexes because pretreatment with anti-human IgG serum caused their disappearance . | {
"id": "C0205161",
"pos": [
39,
47
],
"name": "abnormal"
} | {
"id": "C0020997",
"pos": [
11,
32
],
"name": "immunoelectrophoresis"
} | 0NA |
Damage to one or more of these components produces distinct profiles of impairment in aphasia and dementia . | {
"id": "C0010957",
"pos": [
0,
6
],
"name": "Damage"
} | {
"id": "C0011265",
"pos": [
98,
106
],
"name": "dementia"
} | 0NA |
The changes in the tooth size and skeletal characteristics of the hypodontia group were evaluated using cast/cephalometric analysis and compared with the standard values of normal occlusion in Koreans . | {
"id": "C0037253",
"pos": [
34,
42
],
"name": "skeletal"
} | {
"id": "C0020608",
"pos": [
66,
76
],
"name": "hypodontia"
} | 0NA |
Three patients with generalized tooth wear , suffering from dental pain , masticatory dysfunction , bruxism and neck and back pain , were selected and treated in collaboration with physiotherapists . | {
"id": "C0027530",
"pos": [
112,
116
],
"name": "neck"
} | {
"id": "C0239043",
"pos": [
74,
97
],
"name": "masticatory dysfunction"
} | 0NA |
After hatching , no yolk-sac-derived erythrocytes are found in the peripheral blood . | {
"id": "C0229664",
"pos": [
67,
83
],
"name": "peripheral blood"
} | {
"id": "C0014772",
"pos": [
37,
49
],
"name": "erythrocytes"
} | 0NA |
One was discovered on physical examination and computed tomography and the other diagnosed intraoperatively 1 month later . | {
"id": "C0031809",
"pos": [
22,
42
],
"name": "physical examination"
} | {
"id": "C0040405",
"pos": [
47,
66
],
"name": "computed tomography"
} | 0NA |
Results from logistic regressions indicate that COPD patients with a generic-only benefit are significantly more likely to report that they discussed their OOP costs with their physician ( odds ratio [OR]=9.02 ; 95 % confidence interval [ CI ] , 6.15- 13.22 ) , purchased their medications from another country ( OR=6.70 ; 95 % CI , 3.17 - 14.16 ) and reduced spending on food and clothing ( OR=4.06 ; 95 % CI , 2.70 - 6.12 ) . | {
"id": "C0013227",
"pos": [
278,
289
],
"name": "medications"
} | {
"id": "C0024117",
"pos": [
48,
52
],
"name": "COPD"
} | 0NA |
Genetic factors are major determinants of who will develop IVD degeneration and related back pain , and seem to correlate better with disc degeneration and back pain than do external forces on the spine . | {
"id": "C0011164",
"pos": [
63,
75
],
"name": "degeneration"
} | {
"id": "C0158266",
"pos": [
134,
151
],
"name": "disc degeneration"
} | 3associated_morphology_of |
Entry criteria included patients older than 18 years with more than 3 rib fractures and no contraindications to epidural catheter placement . | {
"id": "C0021107",
"pos": [
130,
139
],
"name": "placement"
} | {
"id": "C0035522",
"pos": [
70,
83
],
"name": "rib fractures"
} | 0NA |
The groups were compared in terms of some clinical ( height , weight and body mass index ) and biochemical parameters ( glucose , triglycerides , cholesterol , low-density lipoprotein and high-density lipoprotein ) . | {
"id": "C0041004",
"pos": [
130,
143
],
"name": "triglycerides"
} | {
"id": "C0017725",
"pos": [
120,
127
],
"name": "glucose"
} | 0NA |
Ocular abnormalities in the embryonic quail were mainly micro-ophthalmic and associated with disproportional growth of the pigmental epithelium and neural retina which resulted in plication and a broken sandwich structure of the retina . | {
"id": "C0035298",
"pos": [
229,
235
],
"name": "retina"
} | {
"id": "C0185026",
"pos": [
180,
189
],
"name": "plication"
} | 0NA |
These observations are consistent with a charge moving mechanism based on a conformational change of the protein ; the weaker temperature sensitivity of the inward rate constant suggests a rate-limiting diffusional component on this process . | {
"id": "C0020517",
"pos": [
138,
149
],
"name": "sensitivity"
} | {
"id": "C0005903",
"pos": [
126,
137
],
"name": "temperature"
} | 0NA |
Immunohistochemically , alpha B crystallin was localized in astrocytes and oligodendrocytes , while HSP28 was present in degenerating neurons in the cerebral cortex of both AD and control brains . | {
"id": "C0011164",
"pos": [
121,
133
],
"name": "degenerating"
} | {
"id": "C0007776",
"pos": [
149,
164
],
"name": "cerebral cortex"
} | 0NA |
Outcomes were reoperation for recurrent DSS , surgery for AR , death and morbidities , including heart transplant , endocarditis and complete heart block . | {
"id": "C0014118",
"pos": [
116,
128
],
"name": "endocarditis"
} | {
"id": "C0018823",
"pos": [
97,
113
],
"name": "heart transplant"
} | 0NA |
Perceived seriousness was not a significant variable in BSE and mammography ( p=0.71 and p=0.43 , respectively ) . | {
"id": "C0024671",
"pos": [
64,
75
],
"name": "mammography"
} | {
"id": "C0085105",
"pos": [
56,
59
],
"name": "BSE"
} | 0NA |
One of the five patients developed ectasia in both eyes . | {
"id": "C0012359",
"pos": [
35,
42
],
"name": "ectasia"
} | {
"id": "C0015392",
"pos": [
51,
55
],
"name": "eyes"
} | 0NA |
Transdermal formulations have been developed to avoid the first-pass hepatic and gastrointestinal drug metabolism responsible for the anticholinergic adverse effects often observed with oral delivery of oxybutynin . | {
"id": "C0017173",
"pos": [
81,
102
],
"name": "gastrointestinal drug"
} | {
"id": "C0069805",
"pos": [
203,
213
],
"name": "oxybutynin"
} | 0NA |
Next , the damaging effects of BB oil diluted with olive oil on liver at different concentrations ( 100 % , 50 % , 20 % ) , were evaluated , using both normal and wounded skin . | {
"id": "C0023884",
"pos": [
64,
69
],
"name": "liver"
} | {
"id": "C0444099",
"pos": [
171,
175
],
"name": "skin"
} | 0NA |
Ablations of the hippocampal formation in 2-month-old infants tested shortly after recovery from surgery resulted in a deficit on a recognition memory task but left intact the ability to learn the concurrent object discrimination task , even though the latter task was administered with the use of a massed practice procedure . | {
"id": "C1261381",
"pos": [
0,
9
],
"name": "Ablations"
} | {
"id": "C0019564",
"pos": [
17,
28
],
"name": "hippocampal"
} | 0NA |
Nor were any differences found between the children who died from measles and the ones who survived . | {
"id": "C0011065",
"pos": [
56,
60
],
"name": "died"
} | {
"id": "C0025007",
"pos": [
66,
73
],
"name": "measles"
} | 0NA |
Fourteen pigs were implanted with pancreatic duct stents by endoscopic procedures . | {
"id": "C0038257",
"pos": [
50,
56
],
"name": "stents"
} | {
"id": "C0282493",
"pos": [
60,
81
],
"name": "endoscopic procedures"
} | 0NA |
Its timing and surgical management could be extremely challenging because extensive adhesions may heavily affect the approach to the abdominal cavity . | {
"id": "C0001511",
"pos": [
84,
93
],
"name": "adhesions"
} | {
"id": "C0230168",
"pos": [
133,
149
],
"name": "abdominal cavity"
} | 0NA |
Ovid Medline and Embase databases were searched for active surveillance , prostate cancer , and MRI from inception until April 25 , 2014 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses process . | {
"id": "C0024485",
"pos": [
96,
99
],
"name": "MRI"
} | {
"id": "C0700325",
"pos": [
52,
71
],
"name": "active surveillance"
} | 0NA |
The patient had high paraprotein concentration ( 85.75 g/l ) and prolonged thrombin time ( 76.8 s ) , activated partial thromboplastin time ( 39.5 s ) , prothrombin time ( 23.5 s ) and reptilase time ( 72.0 s ) . | {
"id": "C0030490",
"pos": [
21,
32
],
"name": "paraprotein"
} | {
"id": "C0033707",
"pos": [
153,
169
],
"name": "prothrombin time"
} | 0NA |
Bands around extremities may be from congenital , infectious , accidental , or purposeful causes . | {
"id": "C0015385",
"pos": [
13,
24
],
"name": "extremities"
} | {
"id": "C0009450",
"pos": [
50,
60
],
"name": "infectious"
} | 0NA |
H. pylori infects the gastric mucosa and its eradication is associated with the prevention of ulcer recurrence . | {
"id": "C0041582",
"pos": [
94,
99
],
"name": "ulcer"
} | {
"id": "C0017136",
"pos": [
22,
36
],
"name": "gastric mucosa"
} | 0NA |
Eighty-six percent of eyes had IOP of ≤18 mmHg with a reduction of 1 medication . | {
"id": "C0015392",
"pos": [
22,
26
],
"name": "eyes"
} | {
"id": "C0578862",
"pos": [
31,
34
],
"name": "IOP"
} | 11finding_site_of |
There were 108/316 ( 34 % ) ' inappropriate ' requests for EEG ; of these 15/108 ( 14 % ) were abnormal . | {
"id": "C0205161",
"pos": [
95,
103
],
"name": "abnormal"
} | {
"id": "C0013819",
"pos": [
59,
62
],
"name": "EEG"
} | 0NA |
Activity of starch synthesizing enzymes is high in the parenchymatous bundle sheath , where they may be involved in the pathway from lipids to soluble carbohydrates . | {
"id": "C0023779",
"pos": [
133,
139
],
"name": "lipids"
} | {
"id": "C0038179",
"pos": [
12,
18
],
"name": "starch"
} | 0NA |
Seven humeri fractured after the fixator removal . | {
"id": "C0016658",
"pos": [
13,
22
],
"name": "fractured"
} | {
"id": "C0015252",
"pos": [
41,
48
],
"name": "removal"
} | 0NA |
To obtain preliminary data on the effectiveness of PBS on sleep-specific health-related quality of life and CPAP adherence . | {
"id": "C0199451",
"pos": [
108,
112
],
"name": "CPAP"
} | {
"id": "C0033770",
"pos": [
51,
54
],
"name": "PBS"
} | 0NA |
Each patient prospectively underwent MRI of the liver prior to percutaneous liver biopsy and quantitative hepatic iron determination . | {
"id": "C0023884",
"pos": [
48,
53
],
"name": "liver"
} | {
"id": "C0558534",
"pos": [
63,
88
],
"name": "percutaneous liver biopsy"
} | 9direct_procedure_site_of |
Surgical repair of peripheral nerves following chronic nerve injury is associated with poor axonal regeneration and outcome . | {
"id": "C0374711",
"pos": [
0,
15
],
"name": "Surgical repair"
} | {
"id": "C0031119",
"pos": [
19,
36
],
"name": "peripheral nerves"
} | 0NA |
Sleep problems and disorders are prevalent in patients with traumatic brain injury ( TBI ) and are associated with negative outcomes . | {
"id": "C0012634",
"pos": [
19,
28
],
"name": "disorders"
} | {
"id": "C0876926",
"pos": [
60,
82
],
"name": "traumatic brain injury"
} | 0NA |
The vascular occluder devices were implanted in the PVL and hemodynamic performance was tested in a pulse duplicator according to international standard ISO 5840 - 3:2013 . | {
"id": "C0021102",
"pos": [
35,
44
],
"name": "implanted"
} | {
"id": "C0023529",
"pos": [
52,
55
],
"name": "PVL"
} | 0NA |
It is important to understand the superimposed effects of subdural hematoma and brain swelling on the veins and sinuses to differentiate it from cortical sinus and venous thrombosis . | {
"id": "C0042449",
"pos": [
102,
107
],
"name": "veins"
} | {
"id": "C0042487",
"pos": [
164,
181
],
"name": "venous thrombosis"
} | 11finding_site_of |
This study was designed to examine the effects of early postnatal injection of PCP on later acquisition and performance of a delayed spatial alternation task , a procedure that is sensitive to manipulations of the prefrontal cortex . | {
"id": "C0184661",
"pos": [
162,
171
],
"name": "procedure"
} | {
"id": "C0021485",
"pos": [
66,
75
],
"name": "injection"
} | 0NA |
We herein report a 34-year-old man who was investigated for severe abdominal pain . | {
"id": "C0205082",
"pos": [
60,
66
],
"name": "severe"
} | {
"id": "C0000737",
"pos": [
67,
81
],
"name": "abdominal pain"
} | 0NA |
These results suggested that the kidney plays a major role in 7B2 degradation and that LH-RH simulates IR-7B2 release from the pituitary gland . | {
"id": "C0022646",
"pos": [
33,
39
],
"name": "kidney"
} | {
"id": "C0032005",
"pos": [
127,
142
],
"name": "pituitary gland"
} | 0NA |
This report presents the results of a genetic analysis of 163 CL + /- P proband families ascertained in Shanghai , China . | {
"id": "C0702111",
"pos": [
72,
79
],
"name": "proband"
} | {
"id": "C0679560",
"pos": [
38,
54
],
"name": "genetic analysis"
} | 15interprets |
Better viral load testing helps direct drug therapies , improving the outlook for AIDS patients . | {
"id": "C0013216",
"pos": [
39,
53
],
"name": "drug therapies"
} | {
"id": "C0004271",
"pos": [
70,
77
],
"name": "outlook"
} | 0NA |
A markedly enlarged left atrium may overlap the aorta . | {
"id": "C0003483",
"pos": [
48,
53
],
"name": "aorta"
} | {
"id": "C0225860",
"pos": [
20,
31
],
"name": "left atrium"
} | 0NA |
Pentavalent antimony is still the drug of choice in the treatment of visceral leishmaniasis . | {
"id": "C0013227",
"pos": [
34,
38
],
"name": "drug"
} | {
"id": "C0023290",
"pos": [
69,
91
],
"name": "visceral leishmaniasis"
} | 0NA |
The gaps and controversies in our understanding of the epidemiologic factors , mechanism , and clinicopathological correlates of CTE reflect the current reliance on postmortem case series investigations . | {
"id": "C1261322",
"pos": [
188,
202
],
"name": "investigations"
} | {
"id": "C0004398",
"pos": [
165,
175
],
"name": "postmortem"
} | 17method_of |
In addition to diabetes mellitus , 28 diseases were explicitly screened for , among them typical macrovascular ( coronary heart disease , cerebrovascular disease , peripheral arterial disease ) and microvascular disease ( neuropathy , nephropathy , retinopathy , diabetic foot ) complications . | {
"id": "C0011849",
"pos": [
15,
32
],
"name": "diabetes mellitus"
} | {
"id": "C0206172",
"pos": [
263,
276
],
"name": "diabetic foot"
} | 5cause_of |
The expression of c-fos mRNA and protein after E2 stimulation was lower in the DES-mice than in the control animals . | {
"id": "C1292856",
"pos": [
50,
61
],
"name": "stimulation"
} | {
"id": "C0033684",
"pos": [
33,
40
],
"name": "protein"
} | 0NA |
The effect of low back pain , with or without nerve root signs , on the joint coordination and kinematics of the lumbar spine and hips during everyday activities , such as picking up an object from the floor , are largely unknown . | {
"id": "C0024091",
"pos": [
113,
125
],
"name": "lumbar spine"
} | {
"id": "C0024031",
"pos": [
14,
27
],
"name": "low back pain"
} | 0NA |
Minor trauma , high blood pressure ( 20 p. 100 of the cases ) , oral contraceptives and coughing have been as well suspected . | {
"id": "C0020538",
"pos": [
15,
34
],
"name": "high blood pressure"
} | {
"id": "C0010200",
"pos": [
88,
96
],
"name": "coughing"
} | 0NA |
We identified a tumor vascular cell profile of ovarian cancer that was distinct from the vascular profile of normal ovary and other tumors . | {
"id": "C0027651",
"pos": [
132,
138
],
"name": "tumors"
} | {
"id": "C0919267",
"pos": [
47,
61
],
"name": "ovarian cancer"
} | 3associated_morphology_of |
Patients were classified into ICAS-O if pre-existing atherosclerotic lesion was identified as the etiology for large vessel occlusion during the thrombectomy . | {
"id": "C0221198",
"pos": [
69,
75
],
"name": "lesion"
} | {
"id": "C0162578",
"pos": [
145,
157
],
"name": "thrombectomy"
} | 0NA |
A functionally intact spleen with a marginal zone , containing B cells with high density of surface C3d-receptors ( CD21 ) , is essential for the ability to induce a primary immune response to thymus-independent type 2 ( TI-2 ) antigens . | {
"id": "C0037993",
"pos": [
22,
28
],
"name": "spleen"
} | {
"id": "C0301872",
"pos": [
174,
189
],
"name": "immune response"
} | 0NA |
The imaging features in the thorax are well described and are traditionally divided into tracheobronchial , nodular parenchymal , and diffuse alveolar septal subtypes . | {
"id": "C0817096",
"pos": [
28,
34
],
"name": "thorax"
} | {
"id": "C0011923",
"pos": [
4,
11
],
"name": "imaging"
} | 0NA |
Data were taken in the present study with respect to the form and latency of the cardiac rate changes produced by intrusion of CS2 ( light ) , across a range of placements varying from simultaneity with CS1 ( a different light ) onset to two sec before UCS would have been delivered . | {
"id": "C0441587",
"pos": [
161,
171
],
"name": "placements"
} | {
"id": "C0018810",
"pos": [
81,
93
],
"name": "cardiac rate"
} | 0NA |
Our data suggest that submucosal MC play significant roles in various aspects of pathophysiology in the gastrointestinal tract by locally providing bioactive LPA through the production of ATX/lysoPLD . | {
"id": "C0017189",
"pos": [
104,
126
],
"name": "gastrointestinal tract"
} | {
"id": "C1096202",
"pos": [
158,
161
],
"name": "LPA"
} | 0NA |
Analyses of the gastrointestinal tracts revealed that the cumulative volume in the stomach and small intestine correlated highly with the amount consumed regardless of which fluid was ingested . | {
"id": "C0021852",
"pos": [
95,
110
],
"name": "small intestine"
} | {
"id": "C0017189",
"pos": [
16,
39
],
"name": "gastrointestinal tracts"
} | 0NA |
In contrast , stimulation by thapsigargin is inhibited by incubation with actinomycin D , 100 mM KCl , BAPTA/AM or in the absence of extracellular Ca2 + . | {
"id": "C1292856",
"pos": [
14,
25
],
"name": "stimulation"
} | {
"id": "C0032825",
"pos": [
97,
100
],
"name": "KCl"
} | 0NA |
These skin grafts consist of both epidermal and dermal compartments necessary for robust and permanent functional wound closure . | {
"id": "C0014520",
"pos": [
34,
43
],
"name": "epidermal"
} | {
"id": "C0037297",
"pos": [
6,
17
],
"name": "skin grafts"
} | 0NA |
The fabrication chemistry is discussed and spectroscopic/microscopic characterizations of silver and gold nanoparticles in poly(vinyl alcohol ) film are presented . | {
"id": "C0037125",
"pos": [
90,
96
],
"name": "silver"
} | {
"id": "C0018026",
"pos": [
101,
105
],
"name": "gold"
} | 0NA |
The haem-containing mono-oxygenase cytochrome P450 3A4 ( CYP3A4 ) and its redox partner NADPH-dependent cytochrome P450 oxidoreductase ( CPR ) are among the most important enzymes in human liver for metabolizing drugs and xenobiotic compounds . | {
"id": "C0023884",
"pos": [
189,
194
],
"name": "liver"
} | {
"id": "C0007203",
"pos": [
137,
140
],
"name": "CPR"
} | 0NA |
The irrigation with tromethamine-E was initiated through the catheter placed percutaneously in the right ureter . | {
"id": "C0022100",
"pos": [
4,
14
],
"name": "irrigation"
} | {
"id": "C0085590",
"pos": [
61,
69
],
"name": "catheter"
} | 0NA |
All patients in each group showed uniform results : pentazocine increased total systemic resistance ( mean increase 17 % ) while buprenorphine lowered it ( mean reduction 12 % ) ( P less than 0.05 ) . | {
"id": "C0006405",
"pos": [
129,
142
],
"name": "buprenorphine"
} | {
"id": "C0030873",
"pos": [
52,
63
],
"name": "pentazocine"
} | 0NA |
Therefore , in intact skeletal muscle , cAMP-dependent phosphorylation does not modulate desensitization . | {
"id": "C0242692",
"pos": [
22,
37
],
"name": "skeletal muscle"
} | {
"id": "C0178702",
"pos": [
89,
104
],
"name": "desensitization"
} | 0NA |
When the diverticulum presents with perforation or obstruction , however , the treatment is a sigmoid colectomy with diverting colostomy ( Hartmann procedure ) . | {
"id": "C0012817",
"pos": [
9,
21
],
"name": "diverticulum"
} | {
"id": "C0009410",
"pos": [
127,
136
],
"name": "colostomy"
} | 0NA |
Fifty-one postmenopausal women with low bone mass were subjected to zoledronate intravenous infusion . | {
"id": "C0574032",
"pos": [
92,
100
],
"name": "infusion"
} | {
"id": "C0232970",
"pos": [
10,
24
],
"name": "postmenopausal"
} | 0NA |
This may have a significant impact on drug and uremic retention solute disposition in CKD patients . | {
"id": "C0013227",
"pos": [
38,
42
],
"name": "drug"
} | {
"id": "C1561643",
"pos": [
86,
89
],
"name": "CKD"
} | 0NA |
The simultaneous use of maternal serum tests designed to screen prenatally for Down syndrome , neural tube defects , and an increased risk of trisomy 18 resulted in a screen-positive result for 90 % of pregnancies with triploidy . | {
"id": "C0041107",
"pos": [
142,
149
],
"name": "trisomy"
} | {
"id": "C0013080",
"pos": [
79,
92
],
"name": "Down syndrome"
} | 3associated_morphology_of |
Patients with moderately severe GERD completed the GSAS and SF-36 at baseline and four weeks following treatment . | {
"id": "C0205082",
"pos": [
25,
31
],
"name": "severe"
} | {
"id": "C0017168",
"pos": [
32,
36
],
"name": "GERD"
} | 0NA |
Including thalidomide , lenalidomide , pomalidomide , bortezomib or carfilzomib in both high-dose and low-dose chemotherapy concepts results in a significantly higher remission rate and longer survival . | {
"id": "C0013216",
"pos": [
111,
123
],
"name": "chemotherapy"
} | {
"id": "C1176309",
"pos": [
54,
64
],
"name": "bortezomib"
} | 0NA |
Independent predictors included patient age , forced expiratory volume in 1 second ( % predicted ) , diffusion capacity of the lung for carbon monoxide ( % predicted ) , performance status , serum creatinine , current cigarette use , and transthoracic resection . | {
"id": "C0024109",
"pos": [
127,
131
],
"name": "lung"
} | {
"id": "C0016529",
"pos": [
46,
70
],
"name": "forced expiratory volume"
} | 0NA |
The intervertebral disks were classified as normal or degenerated on the basis of the MR appearance . | {
"id": "C0011164",
"pos": [
54,
65
],
"name": "degenerated"
} | {
"id": "C0021815",
"pos": [
4,
24
],
"name": "intervertebral disks"
} | 0NA |
Finally , our results demonstrate that groups may experience a crisis differently depending on a combination of personal characteristics such as gender , income , numeracy , and political attitude . | {
"id": "C0231224",
"pos": [
63,
69
],
"name": "crisis"
} | {
"id": "C0079399",
"pos": [
145,
151
],
"name": "gender"
} | 0NA |
A highly efficient Cu-catalyzed 1,2-difunctionalization of various N-heteroarenes was developed with ether and alkyl halide at ambient temperature . | {
"id": "C0014994",
"pos": [
101,
106
],
"name": "ether"
} | {
"id": "C0005903",
"pos": [
135,
146
],
"name": "temperature"
} | 0NA |
Risk factors are primiparity , prolonged labour , instrumental delivery and perineal lacerations . | {
"id": "C0152154",
"pos": [
31,
47
],
"name": "prolonged labour"
} | {
"id": "C0043246",
"pos": [
85,
96
],
"name": "lacerations"
} | 0NA |
The in-depth analysis indicated that the disorder of tricarboxylic acid cycle ( TCA ) , tryptophan metabolism , polyamine metabolism and gut flora structure were associated with DMH intervention . | {
"id": "C0184661",
"pos": [
182,
194
],
"name": "intervention"
} | {
"id": "C0012634",
"pos": [
41,
49
],
"name": "disorder"
} | 0NA |
His detailed postmortem examination is reported . | {
"id": "C0031809",
"pos": [
24,
35
],
"name": "examination"
} | {
"id": "C0004398",
"pos": [
13,
23
],
"name": "postmortem"
} | 17method_of |
The enzyme cocktail was effective in the deinking of old newspaper samples with significant removal of chromophores , phenolics and hydrophobic compounds and less sugar loss . | {
"id": "C0015252",
"pos": [
92,
99
],
"name": "removal"
} | {
"id": "C0359916",
"pos": [
118,
127
],
"name": "phenolics"
} | 0NA |
A 35-year-old woman with severe cystic fibrosis was admitted for sudden loss of strength in both legs , revealing a myelitis . | {
"id": "C1140621",
"pos": [
97,
101
],
"name": "legs"
} | {
"id": "C0010674",
"pos": [
32,
47
],
"name": "cystic fibrosis"
} | 0NA |
Multicomponent NP chains arranged on double-stranded DNA provide a feasible method for fabrication of multifunctional imaging agents that improve relaxation times effectively for MRI applications . | {
"id": "C0024485",
"pos": [
179,
182
],
"name": "MRI"
} | {
"id": "C0185125",
"pos": [
183,
195
],
"name": "applications"
} | 0NA |
Hence , tumors were thought to proliferate and survive independently of integrin attachment to the substratum . | {
"id": "C0027651",
"pos": [
8,
14
],
"name": "tumors"
} | {
"id": "C0185023",
"pos": [
81,
91
],
"name": "attachment"
} | 0NA |
The procedure described in this work opens the way to the application of hybridoma technology to iduronate 2-sulphate sulphatase . | {
"id": "C0184661",
"pos": [
4,
13
],
"name": "procedure"
} | {
"id": "C0185125",
"pos": [
58,
69
],
"name": "application"
} | 0NA |
The object of the study was to investigate the occurrence and localization of oxidative enzymes in the redia -- the third larval stage of Fasciola hepatica L. The author detected cytochrome oxidase , peroxidase , NADH and NADPH tetrazolium reductases ( diaphorases ) , as well as succinate , isocitrate , malate , lactate , alpha-glycerophosphate , glyceraldehyde phosphate , glucose-6-phosphate , 6-phosphogluconate , beta-hydroxybutyrate , L-glutamate , and alcohol dehydrogenases . | {
"id": "C0442726",
"pos": [
170,
178
],
"name": "detected"
} | {
"id": "C0220839",
"pos": [
442,
453
],
"name": "L-glutamate"
} | 0NA |
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