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22 classes
No activity was detected in secretions from male accessory glands including seminal vesicle , epididymis , prostate and coagulating gland ( less than 0.5 U/gland ) .
{ "id": "C0033572", "pos": [ 107, 115 ], "name": "prostate" }
{ "id": "C0086582", "pos": [ 44, 48 ], "name": "male" }
0NA
43 consecutive patients ( excluding non-UK residents ) aged between 2.1 and 56.8 years ( median 7 ) undergoing ASD closure .
{ "id": "C0185003", "pos": [ 115, 122 ], "name": "closure" }
{ "id": "C0018817", "pos": [ 111, 114 ], "name": "ASD" }
0NA
The reopening of the great saphenous vein was observed in 4 limbs ( 15 % ) that did not cause the incompetence of the trunk .
{ "id": "C0015385", "pos": [ 60, 65 ], "name": "limbs" }
{ "id": "C0392907", "pos": [ 21, 41 ], "name": "great saphenous vein" }
0NA
Using high-resolution ultrasound systems the preoperative detection of lesions in the liver achieves the results of CT-scan .
{ "id": "C0221198", "pos": [ 71, 78 ], "name": "lesions" }
{ "id": "C0023884", "pos": [ 86, 91 ], "name": "liver" }
0NA
The main challenges that remain are prevention of H. pylori-related diseases by effective treatment and screening procedures and development of a vaccine , which can address all these issues including beneficial aspects of H. pylori .
{ "id": "C0199176", "pos": [ 36, 46 ], "name": "prevention" }
{ "id": "C0042210", "pos": [ 146, 153 ], "name": "vaccine" }
0NA
Furthermore , hyperplasia and vacuolization were noted in the mucosal epithelium of the urinary bladder .
{ "id": "C0005682", "pos": [ 88, 103 ], "name": "urinary bladder" }
{ "id": "C0026724", "pos": [ 62, 69 ], "name": "mucosal" }
0NA
The late survival of both AAA and AIOD-patients after a successful operation was significantly shorter than that of an age- and sexmatched normal population .
{ "id": "C0543467", "pos": [ 67, 76 ], "name": "operation" }
{ "id": "C0003486", "pos": [ 26, 29 ], "name": "AAA" }
0NA
( 6 ) Combining cholinesterase inhibitors with drugs that reduce the heart rate , depress cardiac conduction , or induce torsades de pointes increases the risk of arrhythmias and cardiac conduction disorders .
{ "id": "C0040479", "pos": [ 121, 140 ], "name": "torsades de pointes" }
{ "id": "C0018810", "pos": [ 69, 79 ], "name": "heart rate" }
15interprets
The results showed that the MIB-1 Labeling Index ( MIB-1 LI ) , MVD and IL-6 increased significantly with advancing severity of disease .
{ "id": "C0021760", "pos": [ 72, 76 ], "name": "IL-6" }
{ "id": "C0012634", "pos": [ 128, 135 ], "name": "disease" }
0NA
Because gastrointestinal endoscopy is widely viewed to be safe , it is probable that the gastrointestinal tract has significant tolerance to light exposure .
{ "id": "C0017189", "pos": [ 89, 111 ], "name": "gastrointestinal tract" }
{ "id": "C0079278", "pos": [ 8, 34 ], "name": "gastrointestinal endoscopy" }
9direct_procedure_site_of
Such an evaluation is often done in a setting of video-EEG monitoring where a strong effort is made to produce seizures as quickly as possible with abrupt changes in medication , alterations in sleep , etc . , which could impact the validity of neuropsychological findings .
{ "id": "C0013227", "pos": [ 166, 176 ], "name": "medication" }
{ "id": "C0036572", "pos": [ 111, 119 ], "name": "seizures" }
0NA
The inter-rater and intra-rater agreement of the new OMERACT definitions for US lesions in GCA was excellent .
{ "id": "C0221198", "pos": [ 80, 87 ], "name": "lesions" }
{ "id": "C0039483", "pos": [ 91, 94 ], "name": "GCA" }
0NA
The amount of starch and lipids per cell increased in Chlorella viscosa and Chlorella vulgaris in sulfur-deficient medium , and long-chain fatty acids with 20 or more carbon atoms accumulated in cells grown in sulfur-deficient medium .
{ "id": "C0023779", "pos": [ 25, 31 ], "name": "lipids" }
{ "id": "C0038179", "pos": [ 14, 20 ], "name": "starch" }
0NA
Cortical fiber cells exhibited increasing damage throughout the observation period without any clear repair after 336h .
{ "id": "C0010957", "pos": [ 42, 48 ], "name": "damage" }
{ "id": "C0043240", "pos": [ 101, 107 ], "name": "repair" }
0NA
Thigh Vo2 was measured by frequent arterial and venous blood sampling and blood flow measurements .
{ "id": "C0003842", "pos": [ 35, 43 ], "name": "arterial" }
{ "id": "C0232338", "pos": [ 74, 84 ], "name": "blood flow" }
0NA
Hence , preoperative attention to cardiovascular disease , hypertension , renal insufficiency , and diabetes mellitus might reduce neurological and cardiovascular complications .
{ "id": "C0007226", "pos": [ 148, 162 ], "name": "cardiovascular" }
{ "id": "C0007222", "pos": [ 34, 56 ], "name": "cardiovascular disease" }
11finding_site_of
Taken together , these findings indicate that during specific treatment of Chagas disease , hepatic pathology may be a result of an interaction between BZ metabolism and specific mechanisms activated during the natural course of T. cruzi infection , rather than an isolated toxic effect of BZ on liver structure and function .
{ "id": "C0041234", "pos": [ 75, 89 ], "name": "Chagas disease" }
{ "id": "C0037420", "pos": [ 132, 143 ], "name": "interaction" }
0NA
The radioactivity of blood showed a rapid decrease until 10 min after injection and a slow decay thereafter .
{ "id": "C0005767", "pos": [ 21, 26 ], "name": "blood" }
{ "id": "C0021485", "pos": [ 70, 79 ], "name": "injection" }
0NA
Reduction , open if necessary , with internal fixation , is recommended for displace fractures : primary arthrodesis is not indicated .
{ "id": "C0016658", "pos": [ 85, 94 ], "name": "fractures" }
{ "id": "C0016642", "pos": [ 37, 54 ], "name": "internal fixation" }
8direct_morphology_of
Childhood sexual abuse can have several negative consequences on pregnancy , birth , and the early neonatal period .
{ "id": "C0205160", "pos": [ 40, 48 ], "name": "negative" }
{ "id": "C0005615", "pos": [ 77, 82 ], "name": "birth" }
0NA
The liver of adult rats with cholestasis secondary to bile duct resection has been shown to express the proenkephalin gene and , by immunohistochemical stains , to contain met-enkephalin .
{ "id": "C0023884", "pos": [ 4, 9 ], "name": "liver" }
{ "id": "C0008370", "pos": [ 29, 40 ], "name": "cholestasis" }
11finding_site_of
Transcatheter methods included accelerated thrombolysis with 325,000 to 1.75 million U of urokinase , adjunct angioplasty , use of intraarterial vasodilators , and creation of pedal arterial flow loops .
{ "id": "C0016504", "pos": [ 176, 181 ], "name": "pedal" }
{ "id": "C0441513", "pos": [ 164, 172 ], "name": "creation" }
0NA
When non-permissive hosts are infected with Angiostrongylus cantonensis , the migration of the worms to the brain and their subsequent development manifests as marked eosinophilic pleocytosis .
{ "id": "C0006104", "pos": [ 108, 113 ], "name": "brain" }
{ "id": "C0018889", "pos": [ 95, 100 ], "name": "worms" }
0NA
We conclude that several biopsy features and elevation of BG are strongly correlated with a high probability of failure ; however , antirejection therapy is justified because recovery of function occurs in some cases .
{ "id": "C0005558", "pos": [ 25, 31 ], "name": "biopsy" }
{ "id": "C0439775", "pos": [ 45, 54 ], "name": "elevation" }
0NA
We observed T cells , B cells , and NK cells in normal mice kidneys after extensive perfusion .
{ "id": "C0022646", "pos": [ 60, 67 ], "name": "kidneys" }
{ "id": "C0031001", "pos": [ 84, 93 ], "name": "perfusion" }
0NA
Our study intended to establish the association between overall survival and vaccine-induced T cell responses against tumor associated antigens ( TAA ) targeted by the vaccine .
{ "id": "C0042210", "pos": [ 168, 175 ], "name": "vaccine" }
{ "id": "C0003486", "pos": [ 146, 149 ], "name": "TAA" }
0NA
Less is known on the application of sutureless prostheses for pure aortic incompetence .
{ "id": "C0003483", "pos": [ 67, 73 ], "name": "aortic" }
{ "id": "C0185125", "pos": [ 21, 32 ], "name": "application" }
0NA
Stenoses of lower extremity arteries were also in the subclinical stage and without intermittent claudications .
{ "id": "C1261287", "pos": [ 0, 8 ], "name": "Stenoses" }
{ "id": "C0311395", "pos": [ 97, 110 ], "name": "claudications" }
0NA
A chemotactic factor for PMN leucocytes was extracted in the pseudoglobulin fraction of burned skin lesions in rabbits and then highly purified by chromatography using Sephadex G-50 , DEAE-Sephadex A-50 and CM-Sephex C-50 in this order .
{ "id": "C0006434", "pos": [ 88, 94 ], "name": "burned" }
{ "id": "C0037284", "pos": [ 95, 107 ], "name": "skin lesions" }
0NA
This potentially increases the risk of peri-operative intra-cranial haemorrhage and thus anti-coagulation therapy is generally considered a contraindication for DBS implantation .
{ "id": "C0394162", "pos": [ 161, 164 ], "name": "DBS" }
{ "id": "C0021107", "pos": [ 165, 177 ], "name": "implantation" }
0NA
We undertook the present study to investigate the role of IL-6 in this disease .
{ "id": "C0021760", "pos": [ 58, 62 ], "name": "IL-6" }
{ "id": "C0012634", "pos": [ 71, 78 ], "name": "disease" }
0NA
To further investigate the differential regulation profile , we examined the protein products of 1alpha-OHase in kidney and skin .
{ "id": "C0022646", "pos": [ 113, 119 ], "name": "kidney" }
{ "id": "C0444099", "pos": [ 124, 128 ], "name": "skin" }
0NA
Here , we present a case of intermittent hematochezia attributed to the overwhelming invasion of the colonic mucosa by intestinal spirochetes .
{ "id": "C0021853", "pos": [ 119, 129 ], "name": "intestinal" }
{ "id": "C0018932", "pos": [ 41, 53 ], "name": "hematochezia" }
0NA
The other type of activity consisted of non-rhythmical nerve potentials whose rate of discharge increased 10 - 30 sec after the injection of adrenaline .
{ "id": "C0021485", "pos": [ 128, 137 ], "name": "injection" }
{ "id": "C0014563", "pos": [ 141, 151 ], "name": "adrenaline" }
0NA
A female patient noticed a painless swelling at the right thigh at the age of 12 .
{ "id": "C0013604", "pos": [ 36, 44 ], "name": "swelling" }
{ "id": "C0230425", "pos": [ 52, 63 ], "name": "right thigh" }
0NA
It is a common complication of acute pancreatitis and trauma of the pancreas .
{ "id": "C0030274", "pos": [ 68, 76 ], "name": "pancreas" }
{ "id": "C0001339", "pos": [ 31, 49 ], "name": "acute pancreatitis" }
11finding_site_of
Studies are in progress to develop vaccines against amoebiasis , malaria and hookworm infections .
{ "id": "C0042210", "pos": [ 35, 43 ], "name": "vaccines" }
{ "id": "C0002438", "pos": [ 52, 62 ], "name": "amoebiasis" }
0NA
Neither the onset of the parent 's illness , nor the mother 's age at delivery , nor the sex of the offspring seemed to influence the rate of PBCs .
{ "id": "C0221423", "pos": [ 35, 42 ], "name": "illness" }
{ "id": "C0011209", "pos": [ 70, 78 ], "name": "delivery" }
0NA
To establish a new model for drug screening to treat lens diseases and investigating lens aging and development , we examined whether human lens epithelial cells ( HLECs ) could be induced into iPSCs and if lens-specific differentiation of these cells could be achieved under defined chemical conditions .
{ "id": "C0023317", "pos": [ 85, 89 ], "name": "lens" }
{ "id": "C0023308", "pos": [ 53, 66 ], "name": "lens diseases" }
11finding_site_of
We report a case of Strongyloides stercoralis infection in a patient , 29 years old young male was admitted to our institution with diarrhea who has got vitamin B12 deficiency and eosinophilia .
{ "id": "C0042847", "pos": [ 153, 175 ], "name": "vitamin B12 deficiency" }
{ "id": "C0086582", "pos": [ 90, 94 ], "name": "male" }
0NA
The study was a retrospective chart review of CRS patients with available sinus CT scans .
{ "id": "C0016169", "pos": [ 74, 79 ], "name": "sinus" }
{ "id": "C0010278", "pos": [ 46, 49 ], "name": "CRS" }
0NA
The most striking fact was an average rate of salivary gland infection ranging from 7.4 to 8.3 % .
{ "id": "C0009450", "pos": [ 61, 70 ], "name": "infection" }
{ "id": "C0036098", "pos": [ 46, 60 ], "name": "salivary gland" }
0NA
Nevertheless , preclinical and early-phase clinical trials suggest that ARV drugs - formulated in vaginal gels , rings , films , tablets and diaphragms - could be effective for HIV chemoprophylaxis .
{ "id": "C0013227", "pos": [ 76, 81 ], "name": "drugs" }
{ "id": "C0282515", "pos": [ 181, 197 ], "name": "chemoprophylaxis" }
10direct_substance_of
No single variable is likely to explain the differences in the reported rates of AKP , although variables leading to abnormal patellofemoral joint loading appear to be of special significance .
{ "id": "C0205161", "pos": [ 117, 125 ], "name": "abnormal" }
{ "id": "C0447801", "pos": [ 126, 146 ], "name": "patellofemoral joint" }
0NA
Hydrocephalus , even in the setting of marked displacement and compression of the brainstem , was not usually seen on MR imaging .
{ "id": "C0024485", "pos": [ 118, 128 ], "name": "MR imaging" }
{ "id": "C0020255", "pos": [ 0, 13 ], "name": "Hydrocephalus" }
0NA
This case-control study explored factors associated with caesarean section delivery , focusing on service-related and individual level factors .
{ "id": "C0011209", "pos": [ 75, 83 ], "name": "delivery" }
{ "id": "C0007876", "pos": [ 57, 74 ], "name": "caesarean section" }
17method_of
It was injected intraocularly in 266 operations ( 73 scleral bucklings , 175 open-sky vitrectomies , among others ) on eyes with complex retinal detachments that were considered inoperable by ordinary surgical techniques .
{ "id": "C0035298", "pos": [ 137, 144 ], "name": "retinal" }
{ "id": "C0036411", "pos": [ 53, 70 ], "name": "scleral bucklings" }
0NA
Dissecting aneurysm of the cerebral arteries have been reported much less frequently than those of the aorta or other extracranial arteries .
{ "id": "C0002940", "pos": [ 11, 19 ], "name": "aneurysm" }
{ "id": "C0003483", "pos": [ 103, 108 ], "name": "aorta" }
0NA
Linear regression equations were obtained for gas analyses data obtained from 85 surgical patients with sepsis and various degrees of illness .
{ "id": "C0221423", "pos": [ 134, 141 ], "name": "illness" }
{ "id": "C0543467", "pos": [ 81, 89 ], "name": "surgical" }
0NA
A postoperative assessment of the treatment results , at 12 months showed an overall improvement in 28 of the 33 limbs : substantial improvement on the condition of limb function and quality of life ( QOL ) , and local and/or systemic sepsis .
{ "id": "C0031809", "pos": [ 16, 26 ], "name": "assessment" }
{ "id": "C0012634", "pos": [ 152, 161 ], "name": "condition" }
0NA
immunoglobulin therapy correlated with the improvement or normalization of the EEG finding .
{ "id": "C0037088", "pos": [ 83, 90 ], "name": "finding" }
{ "id": "C0013819", "pos": [ 79, 82 ], "name": "EEG" }
0NA
The present study was planned with the aim to assess the knowledge , attitude , and practices ( KAP ) regarding hypertension in hypertensive patients visiting Tertiary Care Hospital in North-West India .
{ "id": "C0020538", "pos": [ 112, 124 ], "name": "hypertension" }
{ "id": "C0004271", "pos": [ 69, 77 ], "name": "attitude" }
0NA
Thirty-seven patients with hairy cell leukemia underwent splenectomy .
{ "id": "C0023443", "pos": [ 27, 46 ], "name": "hairy cell leukemia" }
{ "id": "C0037995", "pos": [ 57, 68 ], "name": "splenectomy" }
0NA
The monitor of a video game activity was inverted and placed behind the head of the bed so that the child could maintain proper neck positioning .
{ "id": "C0018670", "pos": [ 72, 76 ], "name": "head" }
{ "id": "C0027530", "pos": [ 128, 132 ], "name": "neck" }
0NA
Cannulation is a procedure that is increasingly being performed by nurses , therefore it is important that they are aware of the complications associated with care and management .
{ "id": "C0184661", "pos": [ 17, 26 ], "name": "procedure" }
{ "id": "C0917707", "pos": [ 0, 11 ], "name": "Cannulation" }
0NA
We have devised an algorithm employing the exclusive use of biosynthetic dressing ( Biobrane ) to treat the less extensive burn wounds of patients under DRG 460 .
{ "id": "C0087111", "pos": [ 98, 103 ], "name": "treat" }
{ "id": "C0006434", "pos": [ 123, 127 ], "name": "burn" }
0NA
In the review are considered aspects of food starch such as its relationship with cancer of the large intestine , its absorption , digestion and metabolism , influence of starch on the composition and biochemical characteristics of microbiocenosis .
{ "id": "C0021853", "pos": [ 102, 111 ], "name": "intestine" }
{ "id": "C0006826", "pos": [ 82, 88 ], "name": "cancer" }
0NA
In late embryonic stages ( EI 410 - 440 microm ) , in stage I juveniles , and in adults , strong positive immunofluorescence was found from the labyrinth up to and including the bladder .
{ "id": "C1446409", "pos": [ 97, 105 ], "name": "positive" }
{ "id": "C0005682", "pos": [ 178, 185 ], "name": "bladder" }
0NA
This anomaly acts as a deletion of chromosomal material and results in specific congenital defects .
{ "id": "C0332447", "pos": [ 5, 12 ], "name": "anomaly" }
{ "id": "C0000768", "pos": [ 80, 98 ], "name": "congenital defects" }
3associated_morphology_of
Abnormal signals were seen in the partial and entire bone marrow in 4 and 3 patients , respectively .
{ "id": "C0205161", "pos": [ 0, 8 ], "name": "Abnormal" }
{ "id": "C0005953", "pos": [ 53, 64 ], "name": "bone marrow" }
0NA
Drugs that target the insulin-like growth factor-I receptor ( IGF-IR ) and/or insulin receptor ( IR ) are currently under investigation for a variety of malignancies including breast cancer .
{ "id": "C0013227", "pos": [ 0, 5 ], "name": "Drugs" }
{ "id": "C0006826", "pos": [ 153, 165 ], "name": "malignancies" }
0NA
Plasma drug level monitoring demonstrated that the pharmacokinetics of ASA were not altered by co-administration of caffeine or NAPAP or vice versa .
{ "id": "C0004057", "pos": [ 71, 74 ], "name": "ASA" }
{ "id": "C0032105", "pos": [ 0, 6 ], "name": "Plasma" }
0NA
Moreover , women have a smaller vessel diameter , more coronary tortuosity and different plaque composition compared to men that can lead to a higher dissection rate and a greater number of procedural complications .
{ "id": "C0005847", "pos": [ 32, 38 ], "name": "vessel" }
{ "id": "C0011389", "pos": [ 89, 95 ], "name": "plaque" }
0NA
Our study in patients with type 2 diabetes showed a reduced average intake of calcium , magnesium and vitamin D compared to standard recommendations , requiring an individualized approach .
{ "id": "C0024467", "pos": [ 88, 97 ], "name": "magnesium" }
{ "id": "C0006675", "pos": [ 78, 85 ], "name": "calcium" }
0NA
Also tested was the wasps ' ability to discriminate between known concentrations of indole , skatole , and androstenone in real boar fat samples at room temperature .
{ "id": "C0021236", "pos": [ 84, 90 ], "name": "indole" }
{ "id": "C0005903", "pos": [ 153, 164 ], "name": "temperature" }
0NA
The Spanish National Discharge Database during the years 2005 - 2006 was used to assess the frequency and clinical impact of VTE and bleeding after elective total knee ( TKA ) or hip ( THA ) arthroplasty .
{ "id": "C0019080", "pos": [ 133, 141 ], "name": "bleeding" }
{ "id": "C0019552", "pos": [ 179, 182 ], "name": "hip" }
0NA
The endocardium in the ventricle and the endothelium in the bulbus arteriosus are described in 3 phylogenetically distant teleostean species , Betta splendens , Pistella riddlei , and Xiphophorus maculatus .
{ "id": "C0014124", "pos": [ 4, 15 ], "name": "endocardium" }
{ "id": "C0018827", "pos": [ 23, 32 ], "name": "ventricle" }
0NA
The broad objective of this review was to describe the experiences of caregivers of people living with HIV/AIDS , in home-based settings in Africa , including the challenges and difficulties of caring as well as the positive aspects .
{ "id": "C1299586", "pos": [ 178, 190 ], "name": "difficulties" }
{ "id": "C0001175", "pos": [ 103, 111 ], "name": "HIV/AIDS" }
0NA
EMG-based muscle activation estimates were assessed by comparison to elbow flexion forces in isometric , two-state isotonic contractions in eleven healthy male subjects .
{ "id": "C0013769", "pos": [ 69, 74 ], "name": "elbow" }
{ "id": "C0086582", "pos": [ 155, 159 ], "name": "male" }
0NA
Leiomyomatosis peritonealis disseminata ( LPD ) is an uncommon condition characterized by multiple nodules of smooth muscle within the peritoneal cavity .
{ "id": "C0031153", "pos": [ 135, 145 ], "name": "peritoneal" }
{ "id": "C0267785", "pos": [ 0, 39 ], "name": "Leiomyomatosis peritonealis disseminata" }
11finding_site_of
Pathological cardiovascular manifestations are reported in four male patients , who had taken massive amounts of anabolic steroids while undergoing many years of strength training .
{ "id": "C0007226", "pos": [ 13, 27 ], "name": "cardiovascular" }
{ "id": "C0086582", "pos": [ 64, 68 ], "name": "male" }
0NA
Cytochrome P450 ( P450 ) 2D6 is a polymorphic human enzyme involved in the oxidation of > 50 drugs , most of which contain a basic nitrogen .
{ "id": "C0013227", "pos": [ 93, 98 ], "name": "drugs" }
{ "id": "C0028158", "pos": [ 131, 139 ], "name": "nitrogen" }
0NA
Using antibodies to the 695 residue amyloid precursor , we have detected using Western blot analysis a protein of approximately 120 kD in samples of cerebral cortex from three subjects with Alzheimer 's disease and one control subject .
{ "id": "C0007776", "pos": [ 149, 164 ], "name": "cerebral cortex" }
{ "id": "C0949466", "pos": [ 79, 100 ], "name": "Western blot analysis" }
0NA
To investigate whether HLA-B27 testing and imaging of the sacroiliac joints are needed in patients with ≤1 spondyloarthritis ( SpA ) feature , referred to a secondary care setting , after medical history collection , clinical examination , and measurement of acute phase reactants .
{ "id": "C0036036", "pos": [ 58, 75 ], "name": "sacroiliac joints" }
{ "id": "C0949690", "pos": [ 107, 124 ], "name": "spondyloarthritis" }
11finding_site_of
This change in vascularization can be detected by combining the use of contrast medium with a highly sensitive measurement technique.(ABSTRACT TRUNCATED AT 250 WORDS )
{ "id": "C0027686", "pos": [ 15, 30 ], "name": "vascularization" }
{ "id": "C0009924", "pos": [ 71, 86 ], "name": "contrast medium" }
0NA
A second approach is to measure the cost of certain iatrogenic manifestations , e.g. fever due to fipexide , stenosis and perforation of the small intestine due to potassium chloride , gastrointestinal bleeding due to NSAIDs , kidney damage due to aminosides , etc .
{ "id": "C0003211", "pos": [ 218, 224 ], "name": "NSAIDs" }
{ "id": "C0017181", "pos": [ 185, 210 ], "name": "gastrointestinal bleeding" }
0NA
At present , prostatic cancer is the most common malignancy in men in many Western countries and its incidence is continuously increasing .
{ "id": "C0006826", "pos": [ 49, 59 ], "name": "malignancy" }
{ "id": "C0376358", "pos": [ 13, 29 ], "name": "prostatic cancer" }
0NA
Fundamental aspects of NMR methodology such as sample preparation , metabolites extraction , quantitative elaboration of spectral data , and statistical analysis have been described .
{ "id": "C0870883", "pos": [ 68, 79 ], "name": "metabolites" }
{ "id": "C0185115", "pos": [ 80, 90 ], "name": "extraction" }
0NA
Microarray showed that the gene encoding cytochrome P450 7B1 ( CYP7B1 ) , an isozyme for bile acid synthesis , was highly expressed in the PAH lung compared with the control .
{ "id": "C0024109", "pos": [ 143, 147 ], "name": "lung" }
{ "id": "C0030123", "pos": [ 139, 142 ], "name": "PAH" }
0NA
The rôle of the endocrine cells which populate the airways of the lung is uncertain , although it has been suggested that one of their functions might be to regulate the pulmonary vasculature .
{ "id": "C0024109", "pos": [ 66, 70 ], "name": "lung" }
{ "id": "C0178987", "pos": [ 51, 58 ], "name": "airways" }
0NA
The EXPAND study examined the real-world efficacy and safety of rivaroxaban for the prevention of stroke and systemic embolism ( SE ) in Japanese patients with non-valvular atrial fibrillation ( NVAF ) .
{ "id": "C0199176", "pos": [ 84, 94 ], "name": "prevention" }
{ "id": "C0038454", "pos": [ 98, 104 ], "name": "stroke" }
0NA
Despite therapeutic levels of phenobarbital , the patient continued to exhibit clinical and electroencephalographic evidence of seizure activity and a midazolam infusion was started at 0.3 mg/kg/h .
{ "id": "C0574032", "pos": [ 161, 169 ], "name": "infusion" }
{ "id": "C0031412", "pos": [ 30, 43 ], "name": "phenobarbital" }
0NA
Abdominal extension of malignant lymphoma is accurately determined ; pretherapeutic staging and followup evaluation of primary retroperitoneal , hepatic and pelvic neoplasms are further indications in selected patients .
{ "id": "C0024299", "pos": [ 23, 41 ], "name": "malignant lymphoma" }
{ "id": "C0030793", "pos": [ 157, 173 ], "name": "pelvic neoplasms" }
0NA
Histopathological evaluation revealed a neoplasm composed of mononuclear cells admixed with osteoclast-like giant cells resembling giant cell tumor of bone .
{ "id": "C0027651", "pos": [ 40, 48 ], "name": "neoplasm" }
{ "id": "C0206638", "pos": [ 131, 155 ], "name": "giant cell tumor of bone" }
0NA
Here we present clinical data and preliminary results of correlative science studies analyzing human epidermal growth factor receptor pathways from the following two prospective Southwest Oncology Group clinical trials performed in advanced stage BAC : S9714 testing a 96-h continuous infusion of paclitaxel ( Taxol ) and S0126 evaluating the small molecule EGFR inhibitor gefitinib ( ZD1839 or Iressa ) .
{ "id": "C0004599", "pos": [ 247, 250 ], "name": "BAC" }
{ "id": "C0144576", "pos": [ 297, 307 ], "name": "paclitaxel" }
0NA
However , behavioral estrus was not observed in any of the cows between days 0 and 7 after GnRH injection .
{ "id": "C0023610", "pos": [ 91, 95 ], "name": "GnRH" }
{ "id": "C0021485", "pos": [ 96, 105 ], "name": "injection" }
0NA
The fibers of the right optic nerve of a 61-year-old man show different arrangements in transverse sections taken from the same individual 5 mm central to the optic canal and 5 mm peripheral to the optic chiasma ; this difference can be recognized by light microscopy ( LM ) , SEM , and AFM .
{ "id": "C0029126", "pos": [ 198, 211 ], "name": "optic chiasma" }
{ "id": "C0430389", "pos": [ 251, 267 ], "name": "light microscopy" }
0NA
The well-known antiepileptics , trimethadione ( TMO ) , ethosuximide ( ESM ) , and phenytoin ( PHT ) , were included as reference drugs .
{ "id": "C0013227", "pos": [ 130, 135 ], "name": "drugs" }
{ "id": "C0041038", "pos": [ 32, 45 ], "name": "trimethadione" }
0NA
Primary leiomyosarcomas of the inferior vena cava ( IVC ) pose unique surgical challenges .
{ "id": "C0042458", "pos": [ 31, 49 ], "name": "inferior vena cava" }
{ "id": "C0543467", "pos": [ 70, 78 ], "name": "surgical" }
0NA
Exposure of children with TT to quinolone ear drops is associated with increased risk of perforations requiring tympanoplasty , which appears to be further exaggerated by corticosteroids .
{ "id": "C0549099", "pos": [ 89, 101 ], "name": "perforations" }
{ "id": "C0041447", "pos": [ 112, 125 ], "name": "tympanoplasty" }
0NA
Invasive electrophysiologic studies are used to guide drug and non-pharmacologic therapy , including surgery , in patients with ventricular tachycardia .
{ "id": "C0013227", "pos": [ 54, 58 ], "name": "drug" }
{ "id": "C0042514", "pos": [ 128, 151 ], "name": "ventricular tachycardia" }
0NA
However , mate choice itself is a costly behaviour also expected to be condition dependent .
{ "id": "C0429964", "pos": [ 81, 90 ], "name": "dependent" }
{ "id": "C0012634", "pos": [ 71, 80 ], "name": "condition" }
0NA
The behavioral tests included open field , elevated plus maze , weight gain , and sucrose preference tests performed 3 , 10 , and 30 days after stopping cocaine .
{ "id": "C0043094", "pos": [ 64, 75 ], "name": "weight gain" }
{ "id": "C0009170", "pos": [ 153, 160 ], "name": "cocaine" }
0NA
During the third or fourth period , MBS ( 1 , 20 or 100 mM ) was washed into the tracheal lumen for 15 min .
{ "id": "C0040578", "pos": [ 81, 89 ], "name": "tracheal" }
{ "id": "C0025344", "pos": [ 27, 33 ], "name": "period" }
0NA
In some children , epicardial pacing may still be desirable because of small patient size , potential for caval obstruction , previous cardiac surgery limiting transvenous access to the heart , or the need to repair congenital heart disease at the time of pacemaker insertion .
{ "id": "C0018787", "pos": [ 186, 191 ], "name": "heart" }
{ "id": "C0018821", "pos": [ 135, 150 ], "name": "cardiac surgery" }
19procedure_site_of
A novel dynamic fugacity-based model is described , developed , and tested that simulates the uptake of narcotic organic chemicals in fish from water as occurs in aquatic bioconcentration and toxicity tests .
{ "id": "C0022885", "pos": [ 201, 206 ], "name": "tests" }
{ "id": "C0043047", "pos": [ 144, 149 ], "name": "water" }
0NA
The method was successfully applied to the analysis of bulk drugs and the recoveries of gemifloxacin and impurities were in the range of 97.60 - 102.90 and 96.99 - 102.10 % , respectively .
{ "id": "C0013227", "pos": [ 60, 65 ], "name": "drugs" }
{ "id": "C0533545", "pos": [ 88, 100 ], "name": "gemifloxacin" }
0NA
All three achieved bone marrow complete remission but had persistent splenomegaly and hypersplenism .
{ "id": "C0005953", "pos": [ 19, 30 ], "name": "bone marrow" }
{ "id": "C0038002", "pos": [ 69, 81 ], "name": "splenomegaly" }
0NA
The venom is also a potential source of toxins with pharmacological and biotechnological applications .
{ "id": "C0042479", "pos": [ 4, 9 ], "name": "venom" }
{ "id": "C0040549", "pos": [ 40, 46 ], "name": "toxins" }
0NA
Serum concentrations of glycine , ammonia , glucose and sodium , and osmolality , were determined during the perioperative period .
{ "id": "C0229671", "pos": [ 0, 5 ], "name": "Serum" }
{ "id": "C0086741", "pos": [ 69, 79 ], "name": "osmolality" }
0NA