query
string
positive
list
negative
list
system
string
What is the biomedical concept corresponding to 'eck'?
[ "eck (homo sapiens)" ]
[ "cek (homo sapiens)", "eek (homo sapiens)", "cek2 (homo sapiens)", "eck (mus musculus)" ]
Given the context 'Using glutathione S-transferase fusion Proteins, it was demonstrated that SLAP bound to activated Eck receptor tyrosine kinase.', answer the user's query.
What is the biomedical concept corresponding to 'slap'?
[ "sla (homo sapiens) (src like adaptor (homo sapiens))", "sla1p (homo sapiens)" ]
[ "sla (sus scrofa) (src like adaptor (sus scrofa))", "slap-2 (homo sapiens)", "sla/lp (homo sapiens)", "slan (homo sapiens)" ]
Given the context 'Therefore, SLAP is a novel candidate downstream signaling intermediate and the first member of the Src family that resembles an adapter molecule.', answer the user's query.
What is the biomedical concept corresponding to 'cb1'?
[ "cb1r (homo sapiens)", "cb1 (homo sapiens)", "cb1a (homo sapiens)", "cannabinoid receptor 1 (homo sapiens)" ]
[ "cb1 (rattus norvegicus)", "cb1r (rattus norvegicus)", "cb1 (mus musculus)", "cb1r (mus musculus)" ]
Given the context 'Two proteins with seven transmembrane-spanning domains typical of guanosine-nucleotide-binding-protein-coupled receptors have been identified as cannabinoid receptors; the central cannabinoid receptor, CB1, and the peripheral cannabinoid receptor, CB2, initially described in rat brain and spleen, respectively.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'Two proteins with seven transmembrane-spanning domains typical of guanosine-nucleotide-binding-protein-coupled receptors have been identified as cannabinoid receptors; the central cannabinoid receptor, CB1, and the peripheral cannabinoid receptor, CB2, initially described in rat brain and spleen, respectively.', answer the user's query.
What is the biomedical concept corresponding to 'cb1'?
[ "cb1r (homo sapiens)", "cb1 (homo sapiens)", "cb1a (homo sapiens)", "cannabinoid receptor 1 (homo sapiens)" ]
[ "cb1 (rattus norvegicus)", "cb1r (rattus norvegicus)", "cb1 (mus musculus)", "cb1r (mus musculus)" ]
Given the context 'Here, we report the distribution patterns for both CB1 and CB2 transcripts in human immune cells and in several human tissues, as analysed using a highly sensitive and quantitative PCR-based method.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'Here, we report the distribution patterns for both CB1 and CB2 transcripts in human immune cells and in several human tissues, as analysed using a highly sensitive and quantitative PCR-based method.', answer the user's query.
What is the biomedical concept corresponding to 'cb1'?
[ "cb1r (homo sapiens)", "cb1 (homo sapiens)", "cb1a (homo sapiens)", "cannabinoid receptor 1 (homo sapiens)" ]
[ "cb1 (rattus norvegicus)", "cb1r (rattus norvegicus)", "cb1 (mus musculus)", "cb1r (mus musculus)" ]
Given the context 'CB1 was mainly expressed in the central nervous system and, to a lower extent, in several peripheral tissues such as adrenal gland, heart, lung, prostate, uterus, ovary, testis, bone marrow, thymus and tonsils.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'In contrast, the CB2 gene, which is not expressed in the brain, was particularly abundant in immune tissues, with an expression level 10-100-fold higher than that of CB1.', answer the user's query.
What is the biomedical concept corresponding to 'cb1'?
[ "cb1r (homo sapiens)", "cb1 (homo sapiens)", "cb1a (homo sapiens)", "cannabinoid receptor 1 (homo sapiens)" ]
[ "cb1 (rattus norvegicus)", "cb1r (rattus norvegicus)", "cb1 (mus musculus)", "cb1r (mus musculus)" ]
Given the context 'In contrast, the CB2 gene, which is not expressed in the brain, was particularly abundant in immune tissues, with an expression level 10-100-fold higher than that of CB1.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'Although CB2 mRNA was also detected in some other peripheral tissues, its level remained very low.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'In spleen and tonsils, the CB2 mRNA content was equivalent to that of CB1 mRNA in the central nervous system.', answer the user's query.
What is the biomedical concept corresponding to 'cb1'?
[ "cb1r (homo sapiens)", "cb1 (homo sapiens)", "cb1a (homo sapiens)", "cannabinoid receptor 1 (homo sapiens)" ]
[ "cb1 (rattus norvegicus)", "cb1r (rattus norvegicus)", "cb1 (mus musculus)", "cb1r (mus musculus)" ]
Given the context 'In spleen and tonsils, the CB2 mRNA content was equivalent to that of CB1 mRNA in the central nervous system.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'Among the main human blood cell subpopulations, the distribution pattern of the CB2 mRNA displayed important variations.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'The rank order of CB2 mRNA levels in these cells was B-cells > natural killer cells >> monocytes > polymorphonuclear neutrophil cells > T8 cells > T4 cells.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'The prevailing expression of the CB2 gene in immune tissues was confirmed by Northern-blot analysis.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'In addition, the expression of the CB2 protein was demonstrated by an immunohistological analysis performed on tonsil sections using specific anti-(human CB2) IgG; this experiment showed that CB2 expression was restricted to B-lymphocyte-enriched areas of the mantle of secondary lymphoid follicles.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'In addition, the expression of the CB2 protein was demonstrated by an immunohistological analysis performed on tonsil sections using specific anti-(human CB2) IgG; this experiment showed that CB2 expression was restricted to B-lymphocyte-enriched areas of the mantle of secondary lymphoid follicles.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'In addition, the expression of the CB2 protein was demonstrated by an immunohistological analysis performed on tonsil sections using specific anti-(human CB2) IgG; this experiment showed that CB2 expression was restricted to B-lymphocyte-enriched areas of the mantle of secondary lymphoid follicles.', answer the user's query.
What is the biomedical concept corresponding to 'cb1'?
[ "cb1r (homo sapiens)", "cb1 (homo sapiens)", "cb1a (homo sapiens)", "cannabinoid receptor 1 (homo sapiens)" ]
[ "cb1 (rattus norvegicus)", "cb1r (rattus norvegicus)", "cb1 (mus musculus)", "cb1r (mus musculus)" ]
Given the context 'These results suggest that (a) CB1 and CB2 can be considered as tissue-selective antigens of the central nervous system and immune system, respectively, and (b) cannabinoids may exert specific receptor-mediated actions on the immune system through the CB2 receptor.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'These results suggest that (a) CB1 and CB2 can be considered as tissue-selective antigens of the central nervous system and immune system, respectively, and (b) cannabinoids may exert specific receptor-mediated actions on the immune system through the CB2 receptor.', answer the user's query.
What is the biomedical concept corresponding to 'cb2'?
[ "cb2 (homo sapiens)", "cannabinoid receptor 2 (homo sapiens)" ]
[ "cc-ckr-2 (homo sapiens)", "gprc2b (homo sapiens)", "cmkbr2 (homo sapiens)", "gababr2 (homo sapiens)" ]
Given the context 'These results suggest that (a) CB1 and CB2 can be considered as tissue-selective antigens of the central nervous system and immune system, respectively, and (b) cannabinoids may exert specific receptor-mediated actions on the immune system through the CB2 receptor.', answer the user's query.
What is the biomedical concept corresponding to 'proteinase-activated receptor 2'?
[ "par2 (homo sapiens) (f2r like trypsin receptor 1 (homo sapiens))", "f2r like trypsin receptor 1 (homo sapiens)" ]
[ "f2r like thrombin or trypsin receptor 3 (homo sapiens)", "proteinase-activated receptor 2-like (gallus gallus)", "par3 (homo sapiens) (coagulation factor ii thrombin receptor like 2 (homo sapiens))", "f2rl2 (homo sapiens)" ]
Given the context 'Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2. ', answer the user's query.
What is the biomedical concept corresponding to 'proteinase-activated receptor 2'?
[ "par2 (homo sapiens) (f2r like trypsin receptor 1 (homo sapiens))", "f2r like trypsin receptor 1 (homo sapiens)" ]
[ "f2r like thrombin or trypsin receptor 3 (homo sapiens)", "proteinase-activated receptor 2-like (gallus gallus)", "par3 (homo sapiens) (coagulation factor ii thrombin receptor like 2 (homo sapiens))", "f2rl2 (homo sapiens)" ]
Given the context 'Since the physiological agonist was unknown, the receptor was named proteinase-activated receptor 2.', answer the user's query.
What is the biomedical concept corresponding to 'proteinase-activated receptor 2'?
[ "par2 (homo sapiens) (f2r like trypsin receptor 1 (homo sapiens))", "f2r like trypsin receptor 1 (homo sapiens)" ]
[ "f2r like thrombin or trypsin receptor 3 (homo sapiens)", "proteinase-activated receptor 2-like (gallus gallus)", "par3 (homo sapiens) (coagulation factor ii thrombin receptor like 2 (homo sapiens))", "f2rl2 (homo sapiens)" ]
Given the context 'By fluorescence in situ hybridization, the human proteinase-activated receptor 2 gene was mapped to chromosomal region 5q13, where, previously, the related thrombin receptor gene has been located.', answer the user's query.
What is the biomedical concept corresponding to 'hep27'?
[ "hep27 (homo sapiens)" ]
[ "hep27 (mus musculus)", "hcp27 (homo sapiens)", "hsf-27 (homo sapiens)", "lc27 (homo sapiens)" ]
Given the context 'We have described a protein (Hep27)', answer the user's query.
What is the biomedical concept corresponding to 'hep27'?
[ "hep27 (homo sapiens)" ]
[ "hep27 (mus musculus)", "hcp27 (homo sapiens)", "hsf-27 (homo sapiens)", "lc27 (homo sapiens)" ]
Given the context 'The synthesis of Hep27 is inhibited in cells that, released from the butyrate block, have resumed DNA synthesis.', answer the user's query.
What is the biomedical concept corresponding to 'hep27'?
[ "hep27 (homo sapiens)" ]
[ "hep27 (mus musculus)", "hcp27 (homo sapiens)", "hsf-27 (homo sapiens)", "lc27 (homo sapiens)" ]
Given the context 'This report describes the cloning and the characterization of the cDNA coding for the Hep27 protein.', answer the user's query.
What is the biomedical concept corresponding to 'hep27'?
[ "hep27 (homo sapiens)" ]
[ "hep27 (mus musculus)", "hcp27 (homo sapiens)", "hsf-27 (homo sapiens)", "lc27 (homo sapiens)" ]
Given the context 'The translation of the Hep27 cDNA predicts an amino acid sequence that can be aligned with those of the known short-chain alcohol dehydrogenase enzymes (SCAD) family.', answer the user's query.
What is the biomedical concept corresponding to 'hep27'?
[ "hep27 (homo sapiens)" ]
[ "hep27 (mus musculus)", "hcp27 (homo sapiens)", "hsf-27 (homo sapiens)", "lc27 (homo sapiens)" ]
Given the context 'In agreement with its nuclear localization Hep27 has a region similar to the bipartite nuclear-targeting sequence.', answer the user's query.
What is the biomedical concept corresponding to 'hep27'?
[ "hep27 (homo sapiens)" ]
[ "hep27 (mus musculus)", "hcp27 (homo sapiens)", "hsf-27 (homo sapiens)", "lc27 (homo sapiens)" ]
Given the context 'The study of Hep27 mRNA expression and protein synthesis suggests the existence of a regulation at the post-transcriptional level.', answer the user's query.
What is the biomedical concept corresponding to 'hep27'?
[ "hep27 (homo sapiens)" ]
[ "hep27 (mus musculus)", "hcp27 (homo sapiens)", "hsf-27 (homo sapiens)", "lc27 (homo sapiens)" ]
Given the context 'The possible nuclear role of the Hep27 protein is discussed.', answer the user's query.
What is the biomedical concept corresponding to 'p53'?
[ "tumor protein p53 (homo sapiens)", "p53 (homo sapiens)", "tp53 (homo sapiens)", "trp53 (homo sapiens)" ]
[ "rad53 (homo sapiens)", "ct53 (homo sapiens)", "p532 (homo sapiens)", "tumor protein p73 (homo sapiens)" ]
Given the context 'Human papillomaviruses (HPVs) are associated with the majority of cervical cancers and encode a transforming protein, E6, that interacts with the tumor suppressor protein p53.', answer the user's query.
What is the biomedical concept corresponding to 'p53'?
[ "tumor protein p53 (homo sapiens)", "p53 (homo sapiens)", "tp53 (homo sapiens)", "trp53 (homo sapiens)" ]
[ "rad53 (homo sapiens)", "ct53 (homo sapiens)", "p532 (homo sapiens)", "tumor protein p73 (homo sapiens)" ]
Given the context 'Because E6 has p53-independent transforming activity, the yeast two-hybrid system was used to search for other E6-binding proteins.', answer the user's query.
What is the biomedical concept corresponding to 'e6bp'?
[ "e6bp (homo sapiens)" ]
[ "protein e6*;transforming protein e6 (human papillomavirus 16)", "e6 (human papillomavirus 16)", "e6-ap (homo sapiens)", "e3bp (homo sapiens)" ]
Given the context 'One such protein, E6BP, interacted with cancer-associated HPV E6 and with bovine papillomavirus type 1 (BPV-1) E6.', answer the user's query.
What is the biomedical concept corresponding to 'e6bp'?
[ "e6bp (homo sapiens)" ]
[ "protein e6*;transforming protein e6 (human papillomavirus 16)", "e6 (human papillomavirus 16)", "e6-ap (homo sapiens)", "e3bp (homo sapiens)" ]
Given the context 'The transforming activity of BPV-1 E6 mutants correlated with their E6BP-binding ability.', answer the user's query.
What is the biomedical concept corresponding to 'e6bp'?
[ "e6bp (homo sapiens)" ]
[ "protein e6*;transforming protein e6 (human papillomavirus 16)", "e6 (human papillomavirus 16)", "e6-ap (homo sapiens)", "e3bp (homo sapiens)" ]
Given the context 'E6BP is identical to a putative calcium-binding protein, ERC-55, that appears to be localized in the endoplasmic reticulum.', answer the user's query.
What is the biomedical concept corresponding to 'erc-55'?
[ "erc-55 (homo sapiens)", "erc55 (homo sapiens)" ]
[ "putative dna-dependent atpase rad55 (saccharomyces cerevisiae s288c)", "testis expressed 55 (homo sapiens)", "rad55 (saccharomyces cerevisiae s288c)", "ercc excision repair 5, endonuclease (homo sapiens)" ]
Given the context 'E6BP is identical to a putative calcium-binding protein, ERC-55, that appears to be localized in the endoplasmic reticulum.', answer the user's query.
What is the biomedical concept corresponding to 'p110 gamma'?
[ "p110gamma (homo sapiens)", "pi3kgamma (homo sapiens)", "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (homo sapiens)", "pik3cg (homo sapiens)" ]
[ "p110gamma (mus musculus)", "p110-alpha (homo sapiens)", "p110beta (homo sapiens)", "phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma (homo sapiens)" ]
Given the context 'A phosphoinositide-3 kinase isotype, p110 gamma, was cloned and characterized.', answer the user's query.
What is the biomedical concept corresponding to 'p110 gamma'?
[ "p110gamma (homo sapiens)", "pi3kgamma (homo sapiens)", "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (homo sapiens)", "pik3cg (homo sapiens)" ]
[ "p110gamma (mus musculus)", "p110-alpha (homo sapiens)", "p110beta (homo sapiens)", "phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma (homo sapiens)" ]
Given the context 'The p110 gamma enzyme was activated in vitro by both the alpha and beta gamma subunits of heterotrimeric guanosine triphosphate (GTP)-binding proteins (G proteins) and did not interact with p85.', answer the user's query.
What is the biomedical concept corresponding to 'p110 gamma'?
[ "p110gamma (homo sapiens)", "pi3kgamma (homo sapiens)", "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (homo sapiens)", "pik3cg (homo sapiens)" ]
[ "p110gamma (mus musculus)", "p110-alpha (homo sapiens)", "p110beta (homo sapiens)", "phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma (homo sapiens)" ]
Given the context 'The p110 gamma isotype may link signaling through G protein-coupled receptors to the generation of phosphoinositide second messengers phosphorylated in the D-3 position.', answer the user's query.
What is the biomedical concept corresponding to 'znf133'?
[ "znf133 (homo sapiens)", "zinc finger protein 133 (homo sapiens)" ]
[ "bzip133 (glycine max)", "rnf133 (homo sapiens)", "zinc finger protein 136 (homo sapiens)", "zinc finger protein 135 (homo sapiens)" ]
Given the context 'ZNF133 and ZNF140 have both the KRAB A- and KRAB B-boxes present at their N-terminus, whereas ZNF136 contains only the KRAB A-box.', answer the user's query.
What is the biomedical concept corresponding to 'znf140'?
[ "znf140 (homo sapiens)", "zinc finger protein 140 (homo sapiens)" ]
[ "znf140l (homo sapiens)", "rnf140 (homo sapiens)", "znf400 (homo sapiens)", "znf40 (homo sapiens)" ]
Given the context 'ZNF133 and ZNF140 have both the KRAB A- and KRAB B-boxes present at their N-terminus, whereas ZNF136 contains only the KRAB A-box.', answer the user's query.
What is the biomedical concept corresponding to 'znf136'?
[ "znf136 (homo sapiens)", "zinc finger protein 136 (homo sapiens)" ]
[ "chromosome 8 c6orf136 homolog (xenopus tropicalis)", "fam161 homolog famh-136 (caenorhabditis elegans)", "rnf136 (homo sapiens)", "ct136 (homo sapiens)" ]
Given the context 'ZNF133 and ZNF140 have both the KRAB A- and KRAB B-boxes present at their N-terminus, whereas ZNF136 contains only the KRAB A-box.', answer the user's query.
What is the biomedical concept corresponding to 'znf133'?
[ "znf133 (homo sapiens)", "zinc finger protein 133 (homo sapiens)" ]
[ "bzip133 (glycine max)", "rnf133 (homo sapiens)", "zinc finger protein 136 (homo sapiens)", "zinc finger protein 135 (homo sapiens)" ]
Given the context 'We have previously demonstrated that the KRAB domains derived from ZNF133 and ZNF140 are potent transcriptional repression domains', answer the user's query.
What is the biomedical concept corresponding to 'znf140'?
[ "znf140 (homo sapiens)", "zinc finger protein 140 (homo sapiens)" ]
[ "znf140l (homo sapiens)", "rnf140 (homo sapiens)", "znf400 (homo sapiens)", "znf40 (homo sapiens)" ]
Given the context 'We have previously demonstrated that the KRAB domains derived from ZNF133 and ZNF140 are potent transcriptional repression domains', answer the user's query.
What is the biomedical concept corresponding to 'znf136'?
[ "znf136 (homo sapiens)", "zinc finger protein 136 (homo sapiens)" ]
[ "chromosome 8 c6orf136 homolog (xenopus tropicalis)", "fam161 homolog famh-136 (caenorhabditis elegans)", "rnf136 (homo sapiens)", "ct136 (homo sapiens)" ]
Given the context 'The KRAB domain from ZNF136, containing only subdomain A, is a considerable weaker suppression domain; however, when fused to the heterologous KRAB B subdomain of ZNF10 (KOX1) the two subdomains from a KRAB domain which induces repression as potently as previously reported KRAB domains.', answer the user's query.
What is the biomedical concept corresponding to 'znf10'?
[ "znf10 (homo sapiens)", "zinc finger protein 10 (homo sapiens)" ]
[ "zinc finger protein 10-like (glycine max)", "zinc finger and btb domain containing 10 (homo sapiens)", "zscan10 (homo sapiens)", "phz-10 (homo sapiens)" ]
Given the context 'The KRAB domain from ZNF136, containing only subdomain A, is a considerable weaker suppression domain; however, when fused to the heterologous KRAB B subdomain of ZNF10 (KOX1) the two subdomains from a KRAB domain which induces repression as potently as previously reported KRAB domains.', answer the user's query.
What is the biomedical concept corresponding to 'kox1'?
[ "kox1 (homo sapiens)" ]
[ "kox-1 (homo sapiens)", "kox (homo sapiens)", "kox3 (homo sapiens)", "kox9 (homo sapiens)" ]
Given the context 'The KRAB domain from ZNF136, containing only subdomain A, is a considerable weaker suppression domain; however, when fused to the heterologous KRAB B subdomain of ZNF10 (KOX1) the two subdomains from a KRAB domain which induces repression as potently as previously reported KRAB domains.', answer the user's query.
What is the biomedical concept corresponding to 'heart voltage-gated sodium-channel alpha-subunit'?
[ "sodium voltage-gated channel alpha subunit 5 (homo sapiens)", "scn5a (homo sapiens) (sodium voltage-gated channel alpha subunit 5 (homo sapiens))", "nav1.5 (homo sapiens)" ]
[ "scnn1a (homo sapiens)", "sodium voltage-gated channel alpha subunit 1 (homo sapiens)", "sodium channel epithelial 1 subunit alpha (homo sapiens)", "scn1a (homo sapiens)" ]
Given the context 'One form of hereditary long QT (LQT3) has been linked to a mutation in the gene encoding the human heart voltage-gated sodium-channel alpha-subunit (SCN5A on chromosome 3p21).', answer the user's query.
What is the biomedical concept corresponding to 'scn5a'?
[ "nav1.5 (homo sapiens)", "scn5a (homo sapiens) (sodium voltage-gated channel alpha subunit 5 (homo sapiens))", "sodium voltage-gated channel alpha subunit 5 (homo sapiens)" ]
[ "scnn1a (homo sapiens)", "scn5a (mus musculus)", "scn5a (sus scrofa)", "scn5a (rattus norvegicus)" ]
Given the context 'One form of hereditary long QT (LQT3) has been linked to a mutation in the gene encoding the human heart voltage-gated sodium-channel alpha-subunit (SCN5A on chromosome 3p21).', answer the user's query.
What is the biomedical concept corresponding to 'eif-4f'?
[ "eif4f (homo sapiens) (eukaryotic translation initiation factor 4e (homo sapiens))", "eukaryotic translation initiation factor 4e (homo sapiens)", "eif-4e (homo sapiens)" ]
[ "4f (drosophila melanogaster) (eip4f (drosophila melanogaster))", "eif4f (drosophila melanogaster) (eukaryotic translation initiation factor 4e4 (drosophila melanogaster))", "eukaryotic translation initiation factor 4e-4 (caenorhabditis elegans)", "eif4f (drosophila melanogaster) (eukaryotic translation initi...
Given the context 'The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC) composed of two cap binding proteins, CBP80 and CBP20.', answer the user's query.
What is the biomedical concept corresponding to 'cbp80'?
[ "cbp80 (homo sapiens)" ]
[ "cbp80 (saccharomyces cerevisiae s288c)", "nuclear cap-binding protein cbp80 (arabidopsis thaliana)", "cbp86 (homo sapiens)", "cbp80 (arabidopsis thaliana)" ]
Given the context 'The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC) composed of two cap binding proteins, CBP80 and CBP20.', answer the user's query.
What is the biomedical concept corresponding to 'cbp20'?
[ "cbp20 (homo sapiens)" ]
[ "cbp20 (saccharomyces cerevisiae s288c)", "cbp20 (drosophila melanogaster)", "cbp20 (xenopus tropicalis)", "cap binding protein 20 (drosophila melanogaster)" ]
Given the context 'The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC) composed of two cap binding proteins, CBP80 and CBP20.', answer the user's query.
What is the biomedical concept corresponding to 'cbp20'?
[ "cbp20 (homo sapiens)" ]
[ "cbp20 (saccharomyces cerevisiae s288c)", "cbp20 (drosophila melanogaster)", "cbp20 (xenopus tropicalis)", "cap binding protein 20 (drosophila melanogaster)" ]
Given the context 'Antibodies against recombinant CBP20 prevent interaction of CBC with capped RNAs in vitro.', answer the user's query.
What is the biomedical concept corresponding to 'carboxypeptidase e'?
[ "carboxypeptidase e (mus musculus)" ]
[ "carboxypeptidase e (homo sapiens)", "carboxypeptidase e (bos taurus)", "carboxypeptidase e (gallus gallus)", "carboxypeptidase e (xenopus tropicalis)" ]
Given the context 'Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity. ', answer the user's query.
What is the biomedical concept corresponding to 'carboxypeptidase e'?
[ "carboxypeptidase e (mus musculus)" ]
[ "carboxypeptidase e (homo sapiens)", "carboxypeptidase e (bos taurus)", "carboxypeptidase e (gallus gallus)", "carboxypeptidase e (xenopus tropicalis)" ]
Given the context 'The fat mutation maps to mouse chromosome 8, very close to the gene for carboxypeptidase E (Cpe), which encodes an enzyme (CPE) that processes prohormone intermediates such as proinsulin.', answer the user's query.
What is the biomedical concept corresponding to 'translin'?
[ "translin (homo sapiens)" ]
[ "translin-like (xenopus tropicalis)", "translin (drosophila melanogaster)", "translin (bos taurus)", "translin (xenopus tropicalis)" ]
Given the context 'A novel gene, Translin, encodes a recombination hotspot binding protein associated with chromosomal translocations. ', answer the user's query.
What is the biomedical concept corresponding to 'translin'?
[ "translin (homo sapiens)" ]
[ "translin-like (xenopus tropicalis)", "translin (drosophila melanogaster)", "translin (bos taurus)", "translin (xenopus tropicalis)" ]
Given the context 'We have identified a novel gene, Translin, encoding a protein which specifically binds to consensus sequences at breakpoint junctions of chromosomal translocations in many cases of lymphoid malignancies.', answer the user's query.
What is the biomedical concept corresponding to 'translin'?
[ "translin (homo sapiens)" ]
[ "translin-like (xenopus tropicalis)", "translin (drosophila melanogaster)", "translin (bos taurus)", "translin (xenopus tropicalis)" ]
Given the context 'The encoded protein, Translin, is a previously undescribed type with no significant similarity to known proteins.', answer the user's query.
What is the biomedical concept corresponding to 'translin'?
[ "translin (homo sapiens)" ]
[ "translin-like (xenopus tropicalis)", "translin (drosophila melanogaster)", "translin (bos taurus)", "translin (xenopus tropicalis)" ]
Given the context 'In the native form, Translin polypeptides form a multimeric structure which is responsible for its DNA binding activity.', answer the user's query.
What is the biomedical concept corresponding to 'translin'?
[ "translin (homo sapiens)" ]
[ "translin-like (xenopus tropicalis)", "translin (drosophila melanogaster)", "translin (bos taurus)", "translin (xenopus tropicalis)" ]
Given the context 'Nuclear localization of Translin is limited to lymphoid cell lines, raising the intriguing possibility that nuclear transport of Translin is regulated in a physiologically significant way such that active nuclear transport is associated with the lymphoid specific process known as Ig/TCR gene rearrangement.', answer the user's query.
What is the biomedical concept corresponding to 'translin'?
[ "translin (homo sapiens)" ]
[ "translin-like (xenopus tropicalis)", "translin (drosophila melanogaster)", "translin (bos taurus)", "translin (xenopus tropicalis)" ]
Given the context 'Nuclear localization of Translin is limited to lymphoid cell lines, raising the intriguing possibility that nuclear transport of Translin is regulated in a physiologically significant way such that active nuclear transport is associated with the lymphoid specific process known as Ig/TCR gene rearrangement.', answer the user's query.
What is the biomedical concept corresponding to 'adhalin'?
[ "adhalin (homo sapiens)" ]
[ "adhalin (xenopus laevis)", "adhalin (xenopus tropicalis)", "ankyrin-1-like (danio rerio)", "adn (homo sapiens)" ]
Given the context 'Marked deficiency of muscle adhalin, a 50 kDa sarcolemmal dystrophin-associated glycoprotein, has been reported in severe childhood autosomal recessive muscular dystrophy (SCARMD).', answer the user's query.
What is the biomedical concept corresponding to '50 kda sarcolemmal dystrophin-associated glycoprotein'?
[ "50dag (homo sapiens)" ]
[ "50dag (mus musculus)", "sarcoglycan, alpha (dystrophin-associated glycoprotein) (mus musculus)", "sarcoglycan, delta (dystrophin-associated glycoprotein) (mus musculus)", "50kda (mus musculus)" ]
Given the context 'Marked deficiency of muscle adhalin, a 50 kDa sarcolemmal dystrophin-associated glycoprotein, has been reported in severe childhood autosomal recessive muscular dystrophy (SCARMD).', answer the user's query.
What is the biomedical concept corresponding to 'adhalin'?
[ "adhalin (homo sapiens)" ]
[ "adhalin (xenopus laevis)", "adhalin (xenopus tropicalis)", "ankyrin-1-like (danio rerio)", "adn (homo sapiens)" ]
Given the context 'Adhalin deficiency has been found in SCARMD patients from North Africa Europe, Brazil, Japan and North America (SLR & KPC, unpublished data).', answer the user's query.
What is the biomedical concept corresponding to 'adhalin'?
[ "adhalin (homo sapiens)" ]
[ "adhalin (xenopus laevis)", "adhalin (xenopus tropicalis)", "ankyrin-1-like (danio rerio)", "adn (homo sapiens)" ]
Given the context 'The disease was initially linked to an unidentified gene on chromosome 13 in families from North Africa, and to the adhalin gene itself on chromosome 17q in one French family in which missense mutations were identified.', answer the user's query.
What is the biomedical concept corresponding to 'adhalin'?
[ "adhalin (homo sapiens)" ]
[ "adhalin (xenopus laevis)", "adhalin (xenopus tropicalis)", "ankyrin-1-like (danio rerio)", "adn (homo sapiens)" ]
Given the context 'Thus there are two kinds of myopathies with adhalin deficiency: one with a primary defect of adhalin (primary adhalinopathies), and one in which absence of adhalin is secondary to a separate gene defect on chromosome 13.', answer the user's query.
What is the biomedical concept corresponding to 'adhalin'?
[ "adhalin (homo sapiens)" ]
[ "adhalin (xenopus laevis)", "adhalin (xenopus tropicalis)", "ankyrin-1-like (danio rerio)", "adn (homo sapiens)" ]
Given the context 'Thus there are two kinds of myopathies with adhalin deficiency: one with a primary defect of adhalin (primary adhalinopathies), and one in which absence of adhalin is secondary to a separate gene defect on chromosome 13.', answer the user's query.
What is the biomedical concept corresponding to 'adhalin'?
[ "adhalin (homo sapiens)" ]
[ "adhalin (xenopus laevis)", "adhalin (xenopus tropicalis)", "ankyrin-1-like (danio rerio)", "adn (homo sapiens)" ]
Given the context 'Thus there are two kinds of myopathies with adhalin deficiency: one with a primary defect of adhalin (primary adhalinopathies), and one in which absence of adhalin is secondary to a separate gene defect on chromosome 13.', answer the user's query.
What is the biomedical concept corresponding to 'adhalin'?
[ "adhalin (homo sapiens)" ]
[ "adhalin (xenopus laevis)", "adhalin (xenopus tropicalis)", "ankyrin-1-like (danio rerio)", "adn (homo sapiens)" ]
Given the context 'We have examined the importance of primary adhalinopathies among myopathies with adhalin deficiency, and describe several additional mutations (null and missense) in the adhalin gene in 10 new families from Europe and North Africa.', answer the user's query.
What is the biomedical concept corresponding to 'adhalin'?
[ "adhalin (homo sapiens)" ]
[ "adhalin (xenopus laevis)", "adhalin (xenopus tropicalis)", "ankyrin-1-like (danio rerio)", "adn (homo sapiens)" ]
Given the context 'We have examined the importance of primary adhalinopathies among myopathies with adhalin deficiency, and describe several additional mutations (null and missense) in the adhalin gene in 10 new families from Europe and North Africa.', answer the user's query.
What is the biomedical concept corresponding to 'rantes receptor'?
[ "c-c motif chemokine receptor 1 (homo sapiens)", "ckr-1 (homo sapiens) (c-c motif chemokine receptor 1 (homo sapiens))" ]
[ "c-x-c motif chemokine receptor 1 (homo sapiens)", "c-x3-c motif chemokine receptor 1 (homo sapiens)", "c-c motif chemokine receptor 6 (homo sapiens)", "ckr-1 (homo sapiens) (c-x-c motif chemokine receptor 1 (homo sapiens))" ]
Given the context 'Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor. ', answer the user's query.
What is the biomedical concept corresponding to 'beta chemokine'?
[ "rantes (homo sapiens)" ]
[ "mip-1-beta (xenopus tropicalis)", "grob (homo sapiens)", "mip-3b (homo sapiens)", "ifn-beta (homo sapiens)" ]
Given the context 'We now show that MIP-1 alpha and the related beta chemokine, RANTES, induce transient alterations in intracellular Ca2+ concentration in polymorphonuclear leukocytes that can be reciprocally and specifically desensitized, suggesting a common receptor.', answer the user's query.
What is the biomedical concept corresponding to 'rantes'?
[ "rantes (homo sapiens)", "ccl5 (homo sapiens)", "scya5 (homo sapiens)" ]
[ "rantes (sus scrofa)", "rantes (xenopus tropicalis)", "mcp-3 (homo sapiens)", "scya6 (homo sapiens)" ]
Given the context 'We now show that MIP-1 alpha and the related beta chemokine, RANTES, induce transient alterations in intracellular Ca2+ concentration in polymorphonuclear leukocytes that can be reciprocally and specifically desensitized, suggesting a common receptor.', answer the user's query.
What is the biomedical concept corresponding to 'interleukin 8'?
[ "il8 (homo sapiens)", "cxcl8 (homo sapiens)", "c-x-c motif chemokine ligand 8 (homo sapiens)" ]
[ "ccl8 (homo sapiens)", "c-c motif chemokine ligand 8 (homo sapiens)", "il1f8 (homo sapiens)", "scya8 (homo sapiens)" ]
Given the context 'It has approximately 33% amino acid identity with receptors for the alpha chemokine, interleukin 8, and may be the human homologue of the product of US28, an open reading frame of human cytomegalovirus.', answer the user's query.
What is the biomedical concept corresponding to 'p57kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "kish2 (homo sapiens)" ]
Given the context 'p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. ', answer the user's query.
What is the biomedical concept corresponding to 'p21cip1'?
[ "p21cip1 (homo sapiens)", "p21 (homo sapiens) (cyclin dependent kinase inhibitor 1a (homo sapiens))", "cip1 (homo sapiens) (cyclin dependent kinase inhibitor 1a (homo sapiens))", "cdkn1 (homo sapiens)", "cyclin dependent kinase inhibitor 1a (homo sapiens)" ]
[ "p-cip1 (homo sapiens)", "inhibitor of cdk, cyclin a1 interacting protein 1 (homo sapiens)", "p27kip1 (homo sapiens)", "p21cip1 (xenopus tropicalis)" ]
Given the context 'p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene. ', answer the user's query.
What is the biomedical concept corresponding to 'p57kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "kish2 (homo sapiens)" ]
Given the context 'We describe a new CKI, p57KIP2, which is related to p21CIP1 and p27KIP1.', answer the user's query.
What is the biomedical concept corresponding to 'p21cip1'?
[ "p21cip1 (homo sapiens)", "p21 (homo sapiens) (cyclin dependent kinase inhibitor 1a (homo sapiens))", "cip1 (homo sapiens) (cyclin dependent kinase inhibitor 1a (homo sapiens))", "cdkn1 (homo sapiens)", "cyclin dependent kinase inhibitor 1a (homo sapiens)" ]
[ "p-cip1 (homo sapiens)", "inhibitor of cdk, cyclin a1 interacting protein 1 (homo sapiens)", "p27kip1 (homo sapiens)", "p21cip1 (xenopus tropicalis)" ]
Given the context 'We describe a new CKI, p57KIP2, which is related to p21CIP1 and p27KIP1.', answer the user's query.
What is the biomedical concept corresponding to 'p27kip1'?
[ "p27kip1 (homo sapiens)", "kip1 (homo sapiens) (cyclin dependent kinase inhibitor 1b (homo sapiens))", "cdkn1b (homo sapiens)" ]
[ "p27k (homo sapiens)", "cdkn1 (homo sapiens)", "p27kip1 (xenopus tropicalis)", "cyclin dependent kinase inhibitor 1a (homo sapiens)" ]
Given the context 'We describe a new CKI, p57KIP2, which is related to p21CIP1 and p27KIP1.', answer the user's query.
What is the biomedical concept corresponding to 'p57kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "kish2 (homo sapiens)" ]
Given the context 'p57KIP2 is a potent, tight-binding inhibitor of several G1 cyclin/Cdk complexes, and its binding is cyclin dependent.', answer the user's query.
What is the biomedical concept corresponding to 'cip1'?
[ "cip1 (homo sapiens) (cyclin dependent kinase inhibitor 1a (homo sapiens))", "cdkn1 (homo sapiens)", "p21cip1 (homo sapiens)" ]
[ "p-cip1 (homo sapiens)", "cip2 (homo sapiens)", "cip3 (homo sapiens)", "cip2a (homo sapiens)" ]
Given the context 'Unlike CIP1, KIP2 is not regulated by p53.', answer the user's query.
What is the biomedical concept corresponding to 'kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens)" ]
Given the context 'Unlike CIP1, KIP2 is not regulated by p53.', answer the user's query.
What is the biomedical concept corresponding to 'p53'?
[ "tumor protein p53 (homo sapiens)", "p53 (homo sapiens)", "tp53 (homo sapiens)", "trp53 (homo sapiens)" ]
[ "rad53 (homo sapiens)", "ct53 (homo sapiens)", "p532 (homo sapiens)", "tumor protein p73 (homo sapiens)" ]
Given the context 'Unlike CIP1, KIP2 is not regulated by p53.', answer the user's query.
What is the biomedical concept corresponding to 'p57kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "kish2 (homo sapiens)" ]
Given the context 'Overexpression of p57KIP2 arrests cells in G1.', answer the user's query.
What is the biomedical concept corresponding to 'p57kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "kish2 (homo sapiens)" ]
Given the context 'p57KIP2 proteins have a complex structure.', answer the user's query.
What is the biomedical concept corresponding to 'p57kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "kish2 (homo sapiens)" ]
Given the context 'Mouse p57KIP2 consists of four structurally distinct domains: an amino-terminal Cdk inhibitory domain, a proline-rich domain, an acidic-repeat region, and a carboxy-terminal domain conserved with p27KIP1.', answer the user's query.
What is the biomedical concept corresponding to 'p27kip1'?
[ "p27kip1 (homo sapiens)", "kip1 (homo sapiens) (cyclin dependent kinase inhibitor 1b (homo sapiens))", "cdkn1b (homo sapiens)" ]
[ "p27k (homo sapiens)", "cdkn1 (homo sapiens)", "p27kip1 (xenopus tropicalis)", "cyclin dependent kinase inhibitor 1a (homo sapiens)" ]
Given the context 'Mouse p57KIP2 consists of four structurally distinct domains: an amino-terminal Cdk inhibitory domain, a proline-rich domain, an acidic-repeat region, and a carboxy-terminal domain conserved with p27KIP1.', answer the user's query.
What is the biomedical concept corresponding to 'p57kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "kish2 (homo sapiens)" ]
Given the context 'Human p57KIP2 appears to have conserved the amino- and carboxy-terminal domains but has replaced the internal regions with sequences containing proline-alanine repeats.', answer the user's query.
What is the biomedical concept corresponding to 'kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens)" ]
Given the context 'In situ hybridization during mouse embryogenesis revealed that KIP2 mRNA displays a striking pattern of expression during development, showing high level expression in skeletal muscle, brain, heart, lungs, and eye.', answer the user's query.
What is the biomedical concept corresponding to 'kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens)" ]
Given the context 'Most of the KIP2-expressing cells are terminally differentiated, suggesting that p57KIP2 is involved in decisions to exit the cell cycle during development and differentiation.', answer the user's query.
What is the biomedical concept corresponding to 'p57kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "kish2 (homo sapiens)" ]
Given the context 'Most of the KIP2-expressing cells are terminally differentiated, suggesting that p57KIP2 is involved in decisions to exit the cell cycle during development and differentiation.', answer the user's query.
What is the biomedical concept corresponding to 'kip2'?
[ "p57kip2 (homo sapiens)", "kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens))" ]
[ "kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens))", "cdkn2c (homo sapiens)", "p-cip2 (homo sapiens)", "calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens)" ]
Given the context 'Human KIP2 is located at 11p15.5, a region implicated in both sporadic cancers and Beckwith-Wiedemann syndrome, a familial cancer syndrome, marking it as a candidate tumor suppressor.', answer the user's query.
What is the biomedical concept corresponding to 'p21cip1'?
[ "p21cip1 (homo sapiens)", "p21 (homo sapiens) (cyclin dependent kinase inhibitor 1a (homo sapiens))", "cip1 (homo sapiens) (cyclin dependent kinase inhibitor 1a (homo sapiens))", "cdkn1 (homo sapiens)", "cyclin dependent kinase inhibitor 1a (homo sapiens)" ]
[ "p-cip1 (homo sapiens)", "inhibitor of cdk, cyclin a1 interacting protein 1 (homo sapiens)", "p27kip1 (homo sapiens)", "p21cip1 (xenopus tropicalis)" ]
Given the context 'The discovery of a new member of the p21CIP1 inhibitor family with novel structural features and expression patterns suggests a complex role for these proteins in cell cycle control and development.', answer the user's query.
What is the biomedical concept corresponding to 'interleukin-1 beta converting enzyme'?
[ "casp1 (homo sapiens)", "caspase 1 (homo sapiens)", "ice (homo sapiens) (caspase 1 (homo sapiens))" ]
[ "casp-7 (homo sapiens)", "casp7 (homo sapiens)", "caspase 7 (homo sapiens)", "ice1 (homo sapiens)" ]
Given the context 'A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells. ', answer the user's query.
What is the biomedical concept corresponding to 'tx'?
[ "tx (homo sapiens)" ]
[ "tx1 (xenopus tropicalis)", "tx1 (xenopus laevis)", "tx (drosophila melanogaster)", "txs (homo sapiens)" ]
Given the context 'We have identified a novel cDNA encoding a protein (named TX) with > 50% overall sequence identity with the interleukin-1 beta converting enzyme (ICE) and approximately 30% sequence identity with the ICE homologs NEDD-2/ICH-1L and CED-3.', answer the user's query.
What is the biomedical concept corresponding to 'interleukin-1 beta converting enzyme'?
[ "casp1 (homo sapiens)", "caspase 1 (homo sapiens)", "ice (homo sapiens) (caspase 1 (homo sapiens))" ]
[ "casp-7 (homo sapiens)", "casp7 (homo sapiens)", "caspase 7 (homo sapiens)", "ice1 (homo sapiens)" ]
Given the context 'We have identified a novel cDNA encoding a protein (named TX) with > 50% overall sequence identity with the interleukin-1 beta converting enzyme (ICE) and approximately 30% sequence identity with the ICE homologs NEDD-2/ICH-1L and CED-3.', answer the user's query.
What is the biomedical concept corresponding to 'ice'?
[ "ice (homo sapiens) (caspase 1 (homo sapiens))" ]
[ "ice1 (homo sapiens)", "ice2 (homo sapiens)", "ice(rel)iii (homo sapiens)", "ice(rel)ii (homo sapiens)" ]
Given the context 'We have identified a novel cDNA encoding a protein (named TX) with > 50% overall sequence identity with the interleukin-1 beta converting enzyme (ICE) and approximately 30% sequence identity with the ICE homologs NEDD-2/ICH-1L and CED-3.', answer the user's query.
What is the biomedical concept corresponding to 'ice'?
[ "ice (homo sapiens) (caspase 1 (homo sapiens))" ]
[ "ice1 (homo sapiens)", "ice2 (homo sapiens)", "ice(rel)iii (homo sapiens)", "ice(rel)ii (homo sapiens)" ]
Given the context 'We have identified a novel cDNA encoding a protein (named TX) with > 50% overall sequence identity with the interleukin-1 beta converting enzyme (ICE) and approximately 30% sequence identity with the ICE homologs NEDD-2/ICH-1L and CED-3.', answer the user's query.
What is the biomedical concept corresponding to 'nedd-2'?
[ "nedd-2 (homo sapiens)", "nedd2 (homo sapiens)" ]
[ "nedd-8 (homo sapiens)", "death regulator nedd2-like caspase (drosophila melanogaster)", "nedd8 (homo sapiens)", "nedd3 (homo sapiens)" ]
Given the context 'We have identified a novel cDNA encoding a protein (named TX) with > 50% overall sequence identity with the interleukin-1 beta converting enzyme (ICE) and approximately 30% sequence identity with the ICE homologs NEDD-2/ICH-1L and CED-3.', answer the user's query.