query string | positive list | negative list | system string |
|---|---|---|---|
What is the biomedical concept corresponding to 'ich-1l'? | [
"ich1 (homo sapiens)"
] | [
"ich-3 (homo sapiens)",
"ich-2 (homo sapiens)",
"ice1 (homo sapiens)",
"casp1 (homo sapiens)"
] | Given the context 'We have identified a novel cDNA encoding a protein (named TX) with > 50% overall sequence identity with the interleukin-1 beta converting enzyme (ICE) and approximately 30% sequence identity with the ICE homologs NEDD-2/ICH-1L and CED-3.', answer the user's query. |
What is the biomedical concept corresponding to 'tx'? | [
"tx (homo sapiens)"
] | [
"tx1 (xenopus tropicalis)",
"tx1 (xenopus laevis)",
"tx (drosophila melanogaster)",
"txs (homo sapiens)"
] | Given the context 'A computer homology model of TX was constructed based on the X-ray coordinates of the ICE crystal recently published.', answer the user's query. |
What is the biomedical concept corresponding to 'ice'? | [
"ice (homo sapiens) (caspase 1 (homo sapiens))"
] | [
"ice1 (homo sapiens)",
"ice2 (homo sapiens)",
"ice(rel)iii (homo sapiens)",
"ice(rel)ii (homo sapiens)"
] | Given the context 'A computer homology model of TX was constructed based on the X-ray coordinates of the ICE crystal recently published.', answer the user's query. |
What is the biomedical concept corresponding to 'tx'? | [
"tx (homo sapiens)"
] | [
"tx1 (xenopus tropicalis)",
"tx1 (xenopus laevis)",
"tx (drosophila melanogaster)",
"txs (homo sapiens)"
] | Given the context 'This model suggests that TX is a cysteine protease, with the P1 aspartic acid substrate specificity retained.', answer the user's query. |
What is the biomedical concept corresponding to 'tx'? | [
"tx (homo sapiens)"
] | [
"tx1 (xenopus tropicalis)",
"tx1 (xenopus laevis)",
"tx (drosophila melanogaster)",
"txs (homo sapiens)"
] | Given the context 'Transfection experiments demonstrate that TX is a protease which is able to cleave itself and the p30 ICE precursor, but not to generate mature IL-1 beta from pro-IL-1 beta.', answer the user's query. |
What is the biomedical concept corresponding to 'ice'? | [
"ice (homo sapiens) (caspase 1 (homo sapiens))"
] | [
"ice1 (homo sapiens)",
"ice2 (homo sapiens)",
"ice(rel)iii (homo sapiens)",
"ice(rel)ii (homo sapiens)"
] | Given the context 'Transfection experiments demonstrate that TX is a protease which is able to cleave itself and the p30 ICE precursor, but not to generate mature IL-1 beta from pro-IL-1 beta.', answer the user's query. |
What is the biomedical concept corresponding to 'il-1 beta'? | [
"interleukin 1 beta (homo sapiens)",
"il1-beta (homo sapiens)",
"il1beta (homo sapiens)",
"il1b (homo sapiens)",
"il-1 (homo sapiens)"
] | [
"interferon beta 1 (homo sapiens)",
"ifn-beta (homo sapiens)",
"interleukin 36 beta (homo sapiens)",
"ifnb1 (homo sapiens)"
] | Given the context 'Transfection experiments demonstrate that TX is a protease which is able to cleave itself and the p30 ICE precursor, but not to generate mature IL-1 beta from pro-IL-1 beta.', answer the user's query. |
What is the biomedical concept corresponding to 'pro-il-1 beta'? | [
"interleukin 1 beta (homo sapiens)",
"il1-beta (homo sapiens)",
"il1beta (homo sapiens)",
"il1b (homo sapiens)",
"il-1 (homo sapiens)"
] | [
"interferon beta 1 (homo sapiens)",
"ifn-beta (homo sapiens)",
"ifnb1 (homo sapiens)",
"il-1a (homo sapiens)"
] | Given the context 'Transfection experiments demonstrate that TX is a protease which is able to cleave itself and the p30 ICE precursor, but not to generate mature IL-1 beta from pro-IL-1 beta.', answer the user's query. |
What is the biomedical concept corresponding to 'tx'? | [
"tx (homo sapiens)"
] | [
"tx1 (xenopus tropicalis)",
"tx1 (xenopus laevis)",
"tx (drosophila melanogaster)",
"txs (homo sapiens)"
] | Given the context 'TX therefore delineates a new member of the growing Ice/ced-3 gene family coding for proteases with cytokine processing activity or involved in programmed cell death.', answer the user's query. |
What is the biomedical concept corresponding to 'e48 antigen'? | [
"e48 (homo sapiens)"
] | [
"dee38 (homo sapiens)",
"e47 (homo sapiens)",
"dee48 (homo sapiens)",
"dee18 (homo sapiens)"
] | Given the context 'The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion.
', answer the user's query. |
What is the biomedical concept corresponding to 'e48 antigen'? | [
"e48 (homo sapiens)"
] | [
"dee38 (homo sapiens)",
"e47 (homo sapiens)",
"dee48 (homo sapiens)",
"dee18 (homo sapiens)"
] | Given the context 'The E48 antigen, a putative human homologue of the 20-kD protein present in desmosomal preparations of bovine muzzle, and formerly called desmoglein III (dg4), is a promising target antigen for antibody-based therapy of squamous cell carcinoma in man.', answer the user's query. |
What is the biomedical concept corresponding to 'desmoglein iii'? | [
"desmoglein 3 (homo sapiens)",
"dsg3 (homo sapiens)"
] | [
"desmoglein 2 (homo sapiens)",
"desmoglein 4 (homo sapiens)",
"desmoglein 1 (homo sapiens)",
"desmoglein 3 (mus musculus)"
] | Given the context 'The E48 antigen, a putative human homologue of the 20-kD protein present in desmosomal preparations of bovine muzzle, and formerly called desmoglein III (dg4), is a promising target antigen for antibody-based therapy of squamous cell carcinoma in man.', answer the user's query. |
What is the biomedical concept corresponding to 'e48 antigen'? | [
"e48 (homo sapiens)"
] | [
"dee38 (homo sapiens)",
"e47 (homo sapiens)",
"dee48 (homo sapiens)",
"dee18 (homo sapiens)"
] | Given the context 'A cDNA clone encoding the E48 antigen was isolated by expression cloning in COS cells.', answer the user's query. |
What is the biomedical concept corresponding to 'e48 antigen'? | [
"e48 (homo sapiens)"
] | [
"dee38 (homo sapiens)",
"e47 (homo sapiens)",
"dee48 (homo sapiens)",
"dee18 (homo sapiens)"
] | Given the context 'Sequence analysis revealed that the clone contained an open reading frame of 128 amino acids, encoding a core protein of 13,286 kD. Database searching showed that the E48 antigen has a high level of sequence similarity with the mouse ThB antigen, a member of the Ly-6 antigen family.', answer the user's query. |
What is the biomedical concept corresponding to 'thb'? | [
"thb (mus musculus)"
] | [
"thbs (bos taurus)",
"thbs (homo sapiens)",
"thbgb (homo sapiens)",
"tcb (homo sapiens)"
] | Given the context 'Sequence analysis revealed that the clone contained an open reading frame of 128 amino acids, encoding a core protein of 13,286 kD. Database searching showed that the E48 antigen has a high level of sequence similarity with the mouse ThB antigen, a member of the Ly-6 antigen family.', answer the user's query. |
What is the biomedical concept corresponding to 'phosphatidylinositol-specific (pi-specific) phospholipase-c'? | [
"plc-ii (homo sapiens)"
] | [
"phosphatidylinositol phospholipase c (saccharomyces cerevisiae s288c)",
"plc-iii (homo sapiens)",
"plc-i (homo sapiens)",
"phosphatidylinositol phospholipase c (candida albicans sc5314)"
] | Given the context 'Phosphatidylinositol-specific (PI-specific) phospholipase-C treatment indicated that the E48 antigen is glycosylphosphatidylinositol-anchored (GPI-anchored) to the plasma membrane.', answer the user's query. |
What is the biomedical concept corresponding to 'e48 antigen'? | [
"e48 (homo sapiens)"
] | [
"dee38 (homo sapiens)",
"e47 (homo sapiens)",
"dee48 (homo sapiens)",
"dee18 (homo sapiens)"
] | Given the context 'Phosphatidylinositol-specific (PI-specific) phospholipase-C treatment indicated that the E48 antigen is glycosylphosphatidylinositol-anchored (GPI-anchored) to the plasma membrane.', answer the user's query. |
What is the biomedical concept corresponding to 'e48 antigen'? | [
"e48 (homo sapiens)"
] | [
"dee38 (homo sapiens)",
"e47 (homo sapiens)",
"dee48 (homo sapiens)",
"dee18 (homo sapiens)"
] | Given the context 'The gene encoding the E48 antigen is a single copy gene, located on human chromosome 8 in the 8q24-qter region.', answer the user's query. |
What is the biomedical concept corresponding to 'thb'? | [
"thb (mus musculus)"
] | [
"thbs (bos taurus)",
"thbs (homo sapiens)",
"thbgb (homo sapiens)",
"tcb (homo sapiens)"
] | Given the context 'The putative mouse homologue, the ThB antigen, originally identified as an antigen on cells of the lymphocyte lineage, was shown to be highly expressed in squamous mouse epithelia.', answer the user's query. |
What is the biomedical concept corresponding to 'thb'? | [
"thb (mus musculus)"
] | [
"thbs (bos taurus)",
"thbs (homo sapiens)",
"thbgb (homo sapiens)",
"tcb (homo sapiens)"
] | Given the context 'Moreover, the ThB expression level is in keratinocytes, in contrast to that in lymphocytes, not mouse strain related.', answer the user's query. |
What is the biomedical concept corresponding to 'e48'? | [
"e48 (homo sapiens)"
] | [
"e47 (homo sapiens)",
"e46 (mus musculus)",
"e4f (homo sapiens)",
"e46l (homo sapiens)"
] | Given the context 'Transfection of mouse SV40-polyoma transformed mouse NIH/3T3 cells with the E48 cDNA confirmed that the antigen is likely to be involved in cell-cell adhesion.', answer the user's query. |
What is the biomedical concept corresponding to 'peroxisomal targeting signal-1 receptor'? | [
"pts1r (homo sapiens)"
] | [
"peroxisomal targeting signal type 2 receptor (arabidopsis thaliana)",
"peroxisomal targeting signal 2 receptor-like (xenopus laevis)",
"peroxisomal biogenesis factor 1 (xenopus tropicalis)",
"pts1r (xenopus laevis)"
] | Given the context 'Human peroxisomal targeting signal-1 receptor restores peroxisomal protein import in cells from patients with fatal peroxisomal disorders.
', answer the user's query. |
What is the biomedical concept corresponding to 'pts1r'? | [
"pts1r (homo sapiens)",
"pts1-bp (homo sapiens)"
] | [
"pts2r (homo sapiens)",
"pts1r (xenopus laevis)",
"pts1 (glycine max)",
"pts (homo sapiens)"
] | Given the context 'We have cloned and sequenced the human cDNA homologue (PTS1R) of the Pichia pastoris PAS8 gene, the PTS1 receptor (McCollum, D., E. Monosov, and S. Subramani.', answer the user's query. |
What is the biomedical concept corresponding to 'pas8'? | [
"pas8 (saccharomyces cerevisiae s288c)"
] | [
"pasd8 (homo sapiens)",
"pas3 (homo sapiens)",
"pas-3 (homo sapiens)",
"pasd6 (homo sapiens)"
] | Given the context 'We have cloned and sequenced the human cDNA homologue (PTS1R) of the Pichia pastoris PAS8 gene, the PTS1 receptor (McCollum, D., E. Monosov, and S. Subramani.', answer the user's query. |
What is the biomedical concept corresponding to 'pts1 receptor'? | [
"pts1r (homo sapiens)",
"pts1-bp (homo sapiens)"
] | [
"pts1r (xenopus laevis)",
"pts1 (glycine max)",
"pts2r (homo sapiens)",
"pts-p1 (homo sapiens)"
] | Given the context 'We have cloned and sequenced the human cDNA homologue (PTS1R) of the Pichia pastoris PAS8 gene, the PTS1 receptor (McCollum, D., E. Monosov, and S. Subramani.', answer the user's query. |
What is the biomedical concept corresponding to 'pts1r'? | [
"pts1r (homo sapiens)",
"pts1-bp (homo sapiens)"
] | [
"pts2r (homo sapiens)",
"pts1r (xenopus laevis)",
"pts1 (glycine max)",
"pts (homo sapiens)"
] | Given the context 'The PTS1R mRNA is expressed in all human tissues examined.', answer the user's query. |
What is the biomedical concept corresponding to 'pts1r'? | [
"pts1r (homo sapiens)",
"pts1-bp (homo sapiens)"
] | [
"pts2r (homo sapiens)",
"pts1r (xenopus laevis)",
"pts1 (glycine max)",
"pts (homo sapiens)"
] | Given the context 'Antibodies to the human PTS1R recognize this protein in human, monkey, rat, and hamster cells.', answer the user's query. |
What is the biomedical concept corresponding to 'pts1r'? | [
"pts1r (homo sapiens)",
"pts1-bp (homo sapiens)"
] | [
"pts2r (homo sapiens)",
"pts1r (xenopus laevis)",
"pts1 (glycine max)",
"pts (homo sapiens)"
] | Given the context 'Part of the peroxisomal PTS1R protein is tightly bound to the peroxisomal membrane.', answer the user's query. |
What is the biomedical concept corresponding to 'pts1r'? | [
"pts1r (homo sapiens)",
"pts1-bp (homo sapiens)"
] | [
"pts2r (homo sapiens)",
"pts1r (xenopus laevis)",
"pts1 (glycine max)",
"pts (homo sapiens)"
] | Given the context 'Antibodies to PTS1R inhibit peroxisomal protein-import of PTS1-containing proteins in a permeabilized CHO cell system.', answer the user's query. |
What is the biomedical concept corresponding to 'pts1r'? | [
"pts1r (homo sapiens)",
"pts1-bp (homo sapiens)"
] | [
"pts2r (homo sapiens)",
"pts1r (xenopus laevis)",
"pts1 (glycine max)",
"pts (homo sapiens)"
] | Given the context 'In vitro-translated PTS1R protein specifically binds a serine-lysine-leucine-peptide.', answer the user's query. |
What is the biomedical concept corresponding to 'pas8'? | [
"pas8 (saccharomyces cerevisiae s288c)"
] | [
"pasd8 (homo sapiens)",
"pas3 (homo sapiens)",
"pas-3 (homo sapiens)",
"pasd6 (homo sapiens)"
] | Given the context 'A PAS8-PTS1R fusion protein complements the P. pastoris pas8 mutant.', answer the user's query. |
What is the biomedical concept corresponding to 'pts1r'? | [
"pts1r (homo sapiens)",
"pts1-bp (homo sapiens)"
] | [
"pts2r (homo sapiens)",
"pts1r (xenopus laevis)",
"pts1 (glycine max)",
"pts (homo sapiens)"
] | Given the context 'A PAS8-PTS1R fusion protein complements the P. pastoris pas8 mutant.', answer the user's query. |
What is the biomedical concept corresponding to 'pas8'? | [
"pas8 (saccharomyces cerevisiae s288c)"
] | [
"pasd8 (homo sapiens)",
"pas3 (homo sapiens)",
"pas-3 (homo sapiens)",
"pasd6 (homo sapiens)"
] | Given the context 'A PAS8-PTS1R fusion protein complements the P. pastoris pas8 mutant.', answer the user's query. |
What is the biomedical concept corresponding to 'pts1r'? | [
"pts1r (homo sapiens)",
"pts1-bp (homo sapiens)"
] | [
"pts2r (homo sapiens)",
"pts1r (xenopus laevis)",
"pts1 (glycine max)",
"pts (homo sapiens)"
] | Given the context 'The PTS1R cDNA also complements the PTS1 protein-import defect in skin fibroblasts from patients--belonging to complementation group two--diagnosed as having neonatal adrenoleukodystrophy or Zellweger syndrome.', answer the user's query. |
What is the biomedical concept corresponding to 'pts1r'? | [
"pts1r (homo sapiens)",
"pts1-bp (homo sapiens)"
] | [
"pts2r (homo sapiens)",
"pts1r (xenopus laevis)",
"pts1 (glycine max)",
"pts (homo sapiens)"
] | Given the context 'The PTS1R gene has been localized to a chromosomal location where no other peroxisomal disorder genes are known to map.', answer the user's query. |
What is the biomedical concept corresponding to 'trkc'? | [
"trkc (homo sapiens)",
"neurotrophic receptor tyrosine kinase 3 (homo sapiens)",
"ntrk3 (homo sapiens)"
] | [
"trkb (homo sapiens)",
"trka (homo sapiens)",
"trkc (rattus norvegicus)",
"ntrk2 (homo sapiens)"
] | Given the context 'Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant.
TrkC is a receptor tyrosine kinase that is activated by neurotrophin-3, a factor important in the development of certain areas of the central nervous system.', answer the user's query. |
What is the biomedical concept corresponding to 'ntrk3'? | [
"ntrk3 (homo sapiens)",
"neurotrophic receptor tyrosine kinase 3 (homo sapiens)"
] | [
"ntrkr3 (homo sapiens)",
"ntrk2 (homo sapiens)",
"ntr3 (homo sapiens)",
"ntrk4 (homo sapiens)"
] | Given the context 'Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant.
TrkC is a receptor tyrosine kinase that is activated by neurotrophin-3, a factor important in the development of certain areas of the central nervous system.', answer the user's query. |
What is the biomedical concept corresponding to 'trkc'? | [
"trkc (homo sapiens)",
"neurotrophic receptor tyrosine kinase 3 (homo sapiens)",
"ntrk3 (homo sapiens)"
] | [
"trkb (homo sapiens)",
"trka (homo sapiens)",
"trkc (rattus norvegicus)",
"ntrk2 (homo sapiens)"
] | Given the context 'Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant.
TrkC is a receptor tyrosine kinase that is activated by neurotrophin-3, a factor important in the development of certain areas of the central nervous system.', answer the user's query. |
What is the biomedical concept corresponding to 'neurotrophin-3'? | [
"neurotrophin 3 (homo sapiens)",
"nt3 (homo sapiens) (neurotrophin 3 (homo sapiens))",
"nt-3 (homo sapiens)",
"ntf3 (homo sapiens)"
] | [
"ntn3 (homo sapiens)",
"neurotrophin 3 (xenopus tropicalis)",
"nt-3 (xenopus tropicalis)",
"neurotrophin-3 (gallus gallus)"
] | Given the context 'Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant.
TrkC is a receptor tyrosine kinase that is activated by neurotrophin-3, a factor important in the development of certain areas of the central nervous system.', answer the user's query. |
What is the biomedical concept corresponding to 'trkc'? | [
"trkc (homo sapiens)",
"neurotrophic receptor tyrosine kinase 3 (homo sapiens)",
"ntrk3 (homo sapiens)"
] | [
"trkb (homo sapiens)",
"trka (homo sapiens)",
"trkc (rattus norvegicus)",
"ntrk2 (homo sapiens)"
] | Given the context 'We have cloned and sequenced the human trkC cDNA and found that the predicted amino acid sequence is 97 to 98% homologous to the rat and porcine trkC sequences, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'trkc'? | [
"trkc (homo sapiens)",
"neurotrophic receptor tyrosine kinase 3 (homo sapiens)",
"ntrk3 (homo sapiens)"
] | [
"trkb (homo sapiens)",
"trka (homo sapiens)",
"trkc (rattus norvegicus)",
"ntrk2 (homo sapiens)"
] | Given the context 'We have cloned and sequenced the human trkC cDNA and found that the predicted amino acid sequence is 97 to 98% homologous to the rat and porcine trkC sequences, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'trkc'? | [
"trkc (homo sapiens)",
"neurotrophic receptor tyrosine kinase 3 (homo sapiens)",
"ntrk3 (homo sapiens)"
] | [
"trkb (homo sapiens)",
"trka (homo sapiens)",
"trkc (rattus norvegicus)",
"ntrk2 (homo sapiens)"
] | Given the context 'The rat trkC has several isoforms due to alternative splicing in the tyrosine kinase domain.', answer the user's query. |
What is the biomedical concept corresponding to 'trkc'? | [
"trkc (homo sapiens)",
"neurotrophic receptor tyrosine kinase 3 (homo sapiens)",
"ntrk3 (homo sapiens)"
] | [
"trkb (homo sapiens)",
"trka (homo sapiens)",
"trkc (rattus norvegicus)",
"ntrk2 (homo sapiens)"
] | Given the context 'The human trkC cDNA also has a (CGG)n repeat in the 5'-untranslated region.', answer the user's query. |
What is the biomedical concept corresponding to 'trkc'? | [
"trkc (homo sapiens)",
"neurotrophic receptor tyrosine kinase 3 (homo sapiens)",
"ntrk3 (homo sapiens)"
] | [
"trkb (homo sapiens)",
"trka (homo sapiens)",
"trkc (rattus norvegicus)",
"ntrk2 (homo sapiens)"
] | Given the context 'By PCR analysis of a somatic cell hybrid panel and fluorescence in situ hybridization with the cDNA clone, human trkC was mapped to chromosome 15q24-q25.', answer the user's query. |
What is the biomedical concept corresponding to 'fibulin-2'? | [
"fibulin 2 (homo sapiens)",
"fbln2 (homo sapiens)"
] | [
"egf containing fibulin extracellular matrix protein 2 (homo sapiens)",
"fibulin 1 (homo sapiens)",
"fibulin 2 (sus scrofa)",
"egf containing fibulin extracellular matrix protein 1 (homo sapiens)"
] | Given the context 'Fibulin-2 (FBLN2): human cDNA sequence, mRNA expression, and mapping of the gene on human and mouse chromosomes.
Fibulin-2 is a new extracellular matrix protein that we recently identified by characterizing mouse cDNA clones.', answer the user's query. |
What is the biomedical concept corresponding to 'fbln2'? | [
"fbln2 (homo sapiens)",
"fibulin 2 (homo sapiens)"
] | [
"fbln3 (homo sapiens)",
"fbln2 (bos taurus)",
"fbln1 (homo sapiens)",
"fbln (homo sapiens)"
] | Given the context 'Fibulin-2 (FBLN2): human cDNA sequence, mRNA expression, and mapping of the gene on human and mouse chromosomes.
Fibulin-2 is a new extracellular matrix protein that we recently identified by characterizing mouse cDNA clones.', answer the user's query. |
What is the biomedical concept corresponding to 'fibulin-2'? | [
"fibulin 2 (homo sapiens)",
"fbln2 (homo sapiens)"
] | [
"egf containing fibulin extracellular matrix protein 2 (homo sapiens)",
"fibulin 1 (homo sapiens)",
"fibulin 2 (sus scrofa)",
"egf containing fibulin extracellular matrix protein 1 (homo sapiens)"
] | Given the context 'Fibulin-2 (FBLN2): human cDNA sequence, mRNA expression, and mapping of the gene on human and mouse chromosomes.
Fibulin-2 is a new extracellular matrix protein that we recently identified by characterizing mouse cDNA clones.', answer the user's query. |
What is the biomedical concept corresponding to 'fibulin-2'? | [
"fibulin 2 (homo sapiens)",
"fbln2 (homo sapiens)"
] | [
"egf containing fibulin extracellular matrix protein 2 (homo sapiens)",
"fibulin 1 (homo sapiens)",
"fibulin 2 (sus scrofa)",
"egf containing fibulin extracellular matrix protein 1 (homo sapiens)"
] | Given the context 'Fibulin-2 mRNA is prominently expressed in mouse heart tissue and is present in low amounts in other tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'fibulin-2'? | [
"fibulin 2 (homo sapiens)",
"fbln2 (homo sapiens)"
] | [
"egf containing fibulin extracellular matrix protein 2 (homo sapiens)",
"fibulin 1 (homo sapiens)",
"fibulin 2 (sus scrofa)",
"egf containing fibulin extracellular matrix protein 1 (homo sapiens)"
] | Given the context 'In this study, we isolated and sequenced a 4.1-kb human fibulin-2 cDNA, which encoded a mature protein of 1157 amino acids preceded by a 27-residue signal sequence.', answer the user's query. |
What is the biomedical concept corresponding to 'fibulin-1'? | [
"fibulin 1 (homo sapiens)",
"fbln1 (homo sapiens)",
"fibl1 (homo sapiens)"
] | [
"egf containing fibulin extracellular matrix protein 1 (homo sapiens)",
"fib1 (homo sapiens)",
"fibin (homo sapiens)",
"fibrillin 1 (homo sapiens)"
] | Given the context 'The 115-residue C-terminal segment (domain III) is similar to the C variant of fibulin-1.', answer the user's query. |
What is the biomedical concept corresponding to 'fibulin-2'? | [
"fibulin 2 (homo sapiens)",
"fbln2 (homo sapiens)"
] | [
"egf containing fibulin extracellular matrix protein 2 (homo sapiens)",
"fibulin 1 (homo sapiens)",
"fibulin 2 (sus scrofa)",
"egf containing fibulin extracellular matrix protein 1 (homo sapiens)"
] | Given the context 'The amino acid sequences of the human and mouse fibulin-2 share approximately 90% identity in domains Na, I, II, and III but only 62% identity in domain Nb.', answer the user's query. |
What is the biomedical concept corresponding to 'fibulin-1'? | [
"fibulin 1 (homo sapiens)",
"fbln1 (homo sapiens)",
"fibl1 (homo sapiens)"
] | [
"egf containing fibulin extracellular matrix protein 1 (homo sapiens)",
"fib1 (homo sapiens)",
"fibin (homo sapiens)",
"fibrillin 1 (homo sapiens)"
] | Given the context 'The expression pattern differs from that of fibulin-1.', answer the user's query. |
What is the biomedical concept corresponding to 'fibulin-2'? | [
"fibulin 2 (homo sapiens)",
"fbln2 (homo sapiens)"
] | [
"egf containing fibulin extracellular matrix protein 2 (homo sapiens)",
"fibulin 1 (homo sapiens)",
"fibulin 2 (sus scrofa)",
"egf containing fibulin extracellular matrix protein 1 (homo sapiens)"
] | Given the context 'The fibulin-2 gene was localized by in situ hybridization to the p24-p25 region of human chromosome 3 and to the band D-E of mouse chromosome 6.', answer the user's query. |
What is the biomedical concept corresponding to 'tata-binding protein'? | [
"tata-box binding protein (homo sapiens)"
] | [
"tata-box binding protein (xenopus tropicalis)",
"tata-box binding protein (bos taurus)",
"tata-box binding protein like 1 (xenopus tropicalis)",
"tata-binding protein (saccharomyces cerevisiae s288c)"
] | Given the context 'TFIID is a multisubunit protein complex comprised of the TATA-binding protein (TBP) and multiple TBP-associated factors (TAFs).', answer the user's query. |
What is the biomedical concept corresponding to 'tbp'? | [
"tbp (homo sapiens)",
"tata-box binding protein (homo sapiens)"
] | [
"tata-box binding protein (bos taurus)",
"tata-box binding protein (xenopus tropicalis)",
"tbp (bos taurus)",
"tbp (xenopus tropicalis) (tata-box binding protein (xenopus tropicalis))"
] | Given the context 'TFIID is a multisubunit protein complex comprised of the TATA-binding protein (TBP) and multiple TBP-associated factors (TAFs).', answer the user's query. |
What is the biomedical concept corresponding to 'tafii55'? | [
"tafii55 (homo sapiens)"
] | [
"tafii55 (xenopus tropicalis)",
"tafii85 (homo sapiens)",
"tafii55 (xenopus laevis)",
"taf5 (saccharomyces cerevisiae s288c)"
] | Given the context 'The cloning of a complementary DNA encoding a human TFIID TAF, TAFII55, that has no known homolog in Drosophila TFIID is now described.', answer the user's query. |
What is the biomedical concept corresponding to 'tafii55'? | [
"tafii55 (homo sapiens)"
] | [
"tafii55 (xenopus tropicalis)",
"tafii85 (homo sapiens)",
"tafii55 (xenopus laevis)",
"taf5 (saccharomyces cerevisiae s288c)"
] | Given the context 'TAFII55 is shown to interact with the largest subunit (TAFII230) of human TFIID through its central region and with multiple activators--including Sp1, YY1, USF, CTF, adenoviral E1A, and human immunodeficiency virus-type 1 Tat proteins--through a distinct amino-terminal domain.', answer the user's query. |
What is the biomedical concept corresponding to 'tafii230'? | [
"tafii-250 (homo sapiens)",
"tafii250 (homo sapiens)"
] | [
"taf23 (saccharomyces cerevisiae s288c)",
"taf[[ii]]230 (drosophila melanogaster) (tbp-associated factor 1 (drosophila melanogaster))",
"taf30 (saccharomyces cerevisiae s288c)",
"taf[[ii]]230 (drosophila melanogaster) (tbp-associated factor 12 (drosophila melanogaster))"
] | Given the context 'TAFII55 is shown to interact with the largest subunit (TAFII230) of human TFIID through its central region and with multiple activators--including Sp1, YY1, USF, CTF, adenoviral E1A, and human immunodeficiency virus-type 1 Tat proteins--through a distinct amino-terminal domain.', answer the user's query. |
What is the biomedical concept corresponding to 'sp1'? | [
"sp1 transcription factor (homo sapiens)",
"sp1 (homo sapiens) (sp1 transcription factor (homo sapiens))"
] | [
"h-sp1 (homo sapiens)",
"sp1 (xenopus tropicalis) (sp1 transcription factor (xenopus tropicalis))",
"sp1 transcription factor (xenopus tropicalis)",
"t-sp1 (homo sapiens)"
] | Given the context 'TAFII55 is shown to interact with the largest subunit (TAFII230) of human TFIID through its central region and with multiple activators--including Sp1, YY1, USF, CTF, adenoviral E1A, and human immunodeficiency virus-type 1 Tat proteins--through a distinct amino-terminal domain.', answer the user's query. |
What is the biomedical concept corresponding to 'yy1'? | [
"yy1 (homo sapiens)",
"yy1 transcription factor (homo sapiens)",
"yin-yang-1 (homo sapiens)"
] | [
"yy1 (xenopus laevis) (yy1 transcription factor s homeolog (xenopus laevis))",
"yy1 transcription factor (xenopus tropicalis)",
"yy1 (drosophila melanogaster)",
"yy1p1 (homo sapiens)"
] | Given the context 'TAFII55 is shown to interact with the largest subunit (TAFII230) of human TFIID through its central region and with multiple activators--including Sp1, YY1, USF, CTF, adenoviral E1A, and human immunodeficiency virus-type 1 Tat proteins--through a distinct amino-terminal domain.', answer the user's query. |
What is the biomedical concept corresponding to 'usf'? | [
"usf1 (homo sapiens)"
] | [
"usf (drosophila melanogaster)",
"usf1p (homo sapiens)",
"usf1 (mus musculus)",
"usf1 (gallus gallus)"
] | Given the context 'TAFII55 is shown to interact with the largest subunit (TAFII230) of human TFIID through its central region and with multiple activators--including Sp1, YY1, USF, CTF, adenoviral E1A, and human immunodeficiency virus-type 1 Tat proteins--through a distinct amino-terminal domain.', answer the user's query. |
What is the biomedical concept corresponding to 'tafii55'? | [
"tafii55 (homo sapiens)"
] | [
"tafii55 (xenopus tropicalis)",
"tafii85 (homo sapiens)",
"tafii55 (xenopus laevis)",
"taf5 (saccharomyces cerevisiae s288c)"
] | Given the context 'The TAFII55-interacting region of Sp1 was localized to its DNA-binding domain, which is distinct from the glutamine-rich activation domains previously shown to interact with Drosophila TAFII110.', answer the user's query. |
What is the biomedical concept corresponding to 'sp1'? | [
"sp1 transcription factor (homo sapiens)",
"sp1 (homo sapiens) (sp1 transcription factor (homo sapiens))"
] | [
"h-sp1 (homo sapiens)",
"sp1 (xenopus tropicalis) (sp1 transcription factor (xenopus tropicalis))",
"sp1 transcription factor (xenopus tropicalis)",
"t-sp1 (homo sapiens)"
] | Given the context 'The TAFII55-interacting region of Sp1 was localized to its DNA-binding domain, which is distinct from the glutamine-rich activation domains previously shown to interact with Drosophila TAFII110.', answer the user's query. |
What is the biomedical concept corresponding to 'ergic-53'? | [
"ergic-53 (homo sapiens)",
"ergic53 (homo sapiens)"
] | [
"ergic-53l (homo sapiens)",
"ergic-53l (mus musculus)",
"ergic-53 (xenopus tropicalis)",
"ergic53 (drosophila melanogaster)"
] | Given the context 'ERGIC-53, a membrane protein of the endoplasmic reticulum-Golgi intermediate compartment, is identical to MR60, an intracellular mannose-specific lectin of myelomonocytic cells.
', answer the user's query. |
What is the biomedical concept corresponding to 'mr60'? | [
"mr60 (homo sapiens)"
] | [
"mrt60 (homo sapiens)",
"mr60 (mus musculus)",
"ct60 (homo sapiens)",
"mic60 (homo sapiens)"
] | Given the context 'ERGIC-53, a membrane protein of the endoplasmic reticulum-Golgi intermediate compartment, is identical to MR60, an intracellular mannose-specific lectin of myelomonocytic cells.
', answer the user's query. |
What is the biomedical concept corresponding to 'mr60'? | [
"mr60 (homo sapiens)"
] | [
"mrt60 (homo sapiens)",
"mr60 (mus musculus)",
"ct60 (homo sapiens)",
"mic60 (homo sapiens)"
] | Given the context 'A mannose-specific membrane lectin (MR60) isolated from human myelomonocytic HL60 cells by affinity chromatography is expressed in intracellular organelles of immature monocytes (Pimpaneau, V., Midoux, P., Monsigny, M., and Roche, A. C. (1991) Carbohydr.', answer the user's query. |
What is the biomedical concept corresponding to 'm(r) 175,000 mannose receptor of mature macrophages'? | [
"mannose receptor c-type 1 (homo sapiens)",
"hmr (homo sapiens) (mannose receptor c-type 1 (homo sapiens))"
] | [
"mannose receptor, c type 1 (mus musculus)",
"mr (mus musculus) (mannose receptor, c type 1 (mus musculus))",
"mannose receptor, c type 2 (mus musculus)",
"mannose receptor c-type 2 (homo sapiens)"
] | Given the context 'It is not present at the cell surface and is immunochemically and structurally distinct from the M(r) 175,000 mannose receptor of mature macrophages.', answer the user's query. |
What is the biomedical concept corresponding to 'mr60'? | [
"mr60 (homo sapiens)"
] | [
"mrt60 (homo sapiens)",
"mr60 (mus musculus)",
"ct60 (homo sapiens)",
"mic60 (homo sapiens)"
] | Given the context 'MR60 cDNA was isolated and characterized; on the basis of its sequence, MR60 is not related to any known mammalian lectins.', answer the user's query. |
What is the biomedical concept corresponding to 'mr60'? | [
"mr60 (homo sapiens)"
] | [
"mrt60 (homo sapiens)",
"mr60 (mus musculus)",
"ct60 (homo sapiens)",
"mic60 (homo sapiens)"
] | Given the context 'MR60 cDNA was isolated and characterized; on the basis of its sequence, MR60 is not related to any known mammalian lectins.', answer the user's query. |
What is the biomedical concept corresponding to 'mr60'? | [
"mr60 (homo sapiens)"
] | [
"mrt60 (homo sapiens)",
"mr60 (mus musculus)",
"ct60 (homo sapiens)",
"mic60 (homo sapiens)"
] | Given the context 'Surprisingly, MR60 was found to be identical to ERGIC-53 (Schindler, R., Itin, C., Zerial, M., Lottspeich, F., and Hauri, H.P. (1993)', answer the user's query. |
What is the biomedical concept corresponding to 'ergic-53'? | [
"ergic-53 (homo sapiens)",
"ergic53 (homo sapiens)"
] | [
"ergic-53l (homo sapiens)",
"ergic-53l (mus musculus)",
"ergic-53 (xenopus tropicalis)",
"ergic53 (drosophila melanogaster)"
] | Given the context 'Surprisingly, MR60 was found to be identical to ERGIC-53 (Schindler, R., Itin, C., Zerial, M., Lottspeich, F., and Hauri, H.P. (1993)', answer the user's query. |
What is the biomedical concept corresponding to 'mr60'? | [
"mr60 (homo sapiens)"
] | [
"mrt60 (homo sapiens)",
"mr60 (mus musculus)",
"ct60 (homo sapiens)",
"mic60 (homo sapiens)"
] | Given the context '61, 1-9), a type I integral membrane protein, defined as a marker of the intermediate compartment that recycles between the Golgi apparatus and endoplasmic reticulum; MR60/ERGIC-53 shares with VIP-36 significant homologies with leguminous plant lectins (Fiedler, K., and Simmons, K. (1994)', answer the user's query. |
What is the biomedical concept corresponding to 'ergic-53'? | [
"ergic-53 (homo sapiens)",
"ergic53 (homo sapiens)"
] | [
"ergic-53l (homo sapiens)",
"ergic-53l (mus musculus)",
"ergic-53 (xenopus tropicalis)",
"ergic53 (drosophila melanogaster)"
] | Given the context '61, 1-9), a type I integral membrane protein, defined as a marker of the intermediate compartment that recycles between the Golgi apparatus and endoplasmic reticulum; MR60/ERGIC-53 shares with VIP-36 significant homologies with leguminous plant lectins (Fiedler, K., and Simmons, K. (1994)', answer the user's query. |
What is the biomedical concept corresponding to 'vip-36'? | [
"vip36 (homo sapiens)"
] | [
"vip36 (xenopus tropicalis)",
"vip36 (mus musculus)",
"vip36 (rattus norvegicus)",
"vacuolar protein sorting 36 homolog (xenopus tropicalis)"
] | Given the context '61, 1-9), a type I integral membrane protein, defined as a marker of the intermediate compartment that recycles between the Golgi apparatus and endoplasmic reticulum; MR60/ERGIC-53 shares with VIP-36 significant homologies with leguminous plant lectins (Fiedler, K., and Simmons, K. (1994)', answer the user's query. |
What is the biomedical concept corresponding to 'mr60'? | [
"mr60 (homo sapiens)"
] | [
"mrt60 (homo sapiens)",
"mr60 (mus musculus)",
"ct60 (homo sapiens)",
"mic60 (homo sapiens)"
] | Given the context 'We extend these findings in evidencing a structural homology between MR60/ERGIC-53 and mammalian galectins (soluble beta galactose binding proteins).', answer the user's query. |
What is the biomedical concept corresponding to 'ergic-53'? | [
"ergic-53 (homo sapiens)",
"ergic53 (homo sapiens)"
] | [
"ergic-53l (homo sapiens)",
"ergic-53l (mus musculus)",
"ergic-53 (xenopus tropicalis)",
"ergic53 (drosophila melanogaster)"
] | Given the context 'We extend these findings in evidencing a structural homology between MR60/ERGIC-53 and mammalian galectins (soluble beta galactose binding proteins).', answer the user's query. |
What is the biomedical concept corresponding to 'mr60'? | [
"mr60 (homo sapiens)"
] | [
"mrt60 (homo sapiens)",
"mr60 (mus musculus)",
"ct60 (homo sapiens)",
"mic60 (homo sapiens)"
] | Given the context 'MR60/ERGIC-53 is the first lectin characterized as an endoplasmic reticulum-Golgi protein.', answer the user's query. |
What is the biomedical concept corresponding to 'ergic-53'? | [
"ergic-53 (homo sapiens)",
"ergic53 (homo sapiens)"
] | [
"ergic-53l (homo sapiens)",
"ergic-53l (mus musculus)",
"ergic-53 (xenopus tropicalis)",
"ergic53 (drosophila melanogaster)"
] | Given the context 'MR60/ERGIC-53 is the first lectin characterized as an endoplasmic reticulum-Golgi protein.', answer the user's query. |
What is the biomedical concept corresponding to 'type 1 tumor necrosis factor receptor'? | [
"tnf receptor superfamily member 1a (homo sapiens)",
"tnf-r (homo sapiens)",
"tnfrsf1a (homo sapiens)",
"tnfr1 (homo sapiens)",
"tnf-r-i (homo sapiens)"
] | [
"tnfbr (homo sapiens)",
"tnf receptor superfamily member 1b (homo sapiens)",
"dcr1-tnfr (homo sapiens)",
"tnfcr (homo sapiens)"
] | Given the context 'Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor.
', answer the user's query. |
What is the biomedical concept corresponding to 'type 1 receptor for tumor necrosis factor'? | [
"tnf receptor superfamily member 1a (homo sapiens)",
"tnf-r (homo sapiens)",
"tnfr1 (homo sapiens)",
"tnfrsf1a (homo sapiens)",
"tnf-r-i (homo sapiens)"
] | [
"tnfbr (homo sapiens)",
"tnfcr (homo sapiens)",
"tnfr-1 (rattus norvegicus)",
"tnf receptor superfamily member 1b (homo sapiens)"
] | Given the context 'The yeast-based two hybrid has been used to identify a novel protein that binds to the intracellular domain of the type 1 receptor for tumor necrosis factor (TNFR-1IC).', answer the user's query. |
What is the biomedical concept corresponding to 'tnfr-1ic'? | [
"tnf-r-i (homo sapiens)",
"tnfar (homo sapiens)",
"tnf-r (homo sapiens)"
] | [
"tnfcr (homo sapiens)",
"tnfbr (homo sapiens)",
"tnf-r-ii (homo sapiens)",
"tnfr-rp (homo sapiens)"
] | Given the context 'The yeast-based two hybrid has been used to identify a novel protein that binds to the intracellular domain of the type 1 receptor for tumor necrosis factor (TNFR-1IC).', answer the user's query. |
What is the biomedical concept corresponding to 'tnfr-1ic'? | [
"tnf-r-i (homo sapiens)",
"tnfar (homo sapiens)",
"tnf-r (homo sapiens)"
] | [
"tnfcr (homo sapiens)",
"tnfbr (homo sapiens)",
"tnf-r-ii (homo sapiens)",
"tnfr-rp (homo sapiens)"
] | Given the context 'After in vitro transcription/translation and 35S labeling, TRAP-1 was precipitated using a fusion protein consisting of glutathione S-transferase and TNFR-1IC, showing that the two proteins directly interact.', answer the user's query. |
What is the biomedical concept corresponding to 'tnfr-1'? | [
"tnf-r (homo sapiens)",
"tnf receptor superfamily member 1a (homo sapiens)",
"tnfrsf1a (homo sapiens)",
"tnfar (homo sapiens)",
"tnf-r-i (homo sapiens)"
] | [
"tnfbr (homo sapiens)",
"tnfcr (homo sapiens)",
"tnf receptor superfamily member 1b (homo sapiens)",
"tnfr-rp (homo sapiens)"
] | Given the context 'The ability of deletion mutants of TNFR-1 to interact with TRAP-1 was tested using the two hybrid system.', answer the user's query. |
What is the biomedical concept corresponding to 'tnfr-1ic'? | [
"tnf-r-i (homo sapiens)",
"tnfar (homo sapiens)",
"tnf-r (homo sapiens)"
] | [
"tnfcr (homo sapiens)",
"tnfbr (homo sapiens)",
"tnf-r-ii (homo sapiens)",
"tnfr-rp (homo sapiens)"
] | Given the context 'This showed that the amino acid sequences that mediate binding are diffusely distributed outside of the domain in the C terminus of TNFR-1IC that signals cytotoxicity.', answer the user's query. |
What is the biomedical concept corresponding to 'tnfr-1'? | [
"tnf-r (homo sapiens)",
"tnf receptor superfamily member 1a (homo sapiens)",
"tnfrsf1a (homo sapiens)",
"tnfar (homo sapiens)",
"tnf-r-i (homo sapiens)"
] | [
"tnfbr (homo sapiens)",
"tnfcr (homo sapiens)",
"tnf receptor superfamily member 1b (homo sapiens)",
"tnfr-rp (homo sapiens)"
] | Given the context 'Identification of TRAP-1 may be an important step toward defining how TNFR-1, which does not contain protein tyrosine kinase activity, transmits its message to signal transduction pathways.', answer the user's query. |
What is the biomedical concept corresponding to 'stomach alcohol dehydrogenase'? | [
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)",
"adh7 (homo sapiens)"
] | [
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus)",
"alcohol dehydrogenase 6 (class v) (rattus norvegicus)",
"alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase 6a (class v) (rattus norvegicus)"
] | Given the context 'Expression and kinetic characterization of recombinant human stomach alcohol dehydrogenase.', answer the user's query. |
What is the biomedical concept corresponding to 'class iv alcohol dehydrogenase'? | [
"adh4 (homo sapiens) (alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens))",
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)"
] | [
"alcohol dehydrogenase 4 (class ii), pi polypeptide (homo sapiens)",
"adh4 (homo sapiens) (alcohol dehydrogenase 4 (class ii), pi polypeptide (homo sapiens))",
"alcohol dehydrogenase 4 (class ii), pi polypeptide (rattus norvegicus)",
"alcohol dehydrogenase adh4 (saccharomyces cerevisiae s288c)"
] | Given the context 'A full-length 1966-base pair clone of the human class IV alcohol dehydrogenase (sigma-ADH) was isolated from a human stomach cDNA library.', answer the user's query. |
What is the biomedical concept corresponding to 'sigma-adh'? | [
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)",
"adh4 (homo sapiens) (alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens))"
] | [
"alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus)",
"alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c)"
] | Given the context 'A full-length 1966-base pair clone of the human class IV alcohol dehydrogenase (sigma-ADH) was isolated from a human stomach cDNA library.', answer the user's query. |
What is the biomedical concept corresponding to 'sigma-adh'? | [
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)",
"adh4 (homo sapiens) (alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens))"
] | [
"alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus)",
"alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c)"
] | Given the context 'The 373-amino acid sigma-ADH encoded by this cDNA was expressed in Escherichia coli.', answer the user's query. |
What is the biomedical concept corresponding to 'sigma-adh'? | [
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)",
"adh4 (homo sapiens) (alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens))"
] | [
"alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus)",
"alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c)"
] | Given the context 'Kinetic analysis of the catalytic efficiency (kcat/KM) of recombinant sigma-ADH for oxidation of primary alcohols indicated broad substrate specificity.', answer the user's query. |
What is the biomedical concept corresponding to 'sigma-adh'? | [
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)",
"adh4 (homo sapiens) (alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens))"
] | [
"alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus)",
"alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c)"
] | Given the context 'Recombinant human sigma-ADH exhibited high catalytic efficiency for oxidation of all-trans-retinol to all-trans-retinal.', answer the user's query. |
What is the biomedical concept corresponding to 'sigma-adh'? | [
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)",
"adh4 (homo sapiens) (alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens))"
] | [
"alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus)",
"alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c)"
] | Given the context 'Secondary alcohols and 3 beta-hydroxysteroids were inactive with sigma-ADH or were oxidized with very low efficiency.', answer the user's query. |
What is the biomedical concept corresponding to 'sigma-adh'? | [
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)",
"adh4 (homo sapiens) (alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens))"
] | [
"alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus)",
"alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c)"
] | Given the context 'The KM of sigma-ADH for ethanol was 25 mM, and the KM for primary straight chain alcohols decreased substantially as chain length increased.', answer the user's query. |
What is the biomedical concept corresponding to 'class i (beta) alcohol dehydrogenases'? | [
"alcohol dehydrogenase 1b (class i), beta polypeptide (homo sapiens)",
"adh1b (homo sapiens)"
] | [
"alcohol dehydrogenase 1b (class i), beta polypeptide (bos taurus)",
"alcohol dehydrogenase 1b (class i), beta polypeptide (xenopus tropicalis)",
"alcohol dehydrogenase 1a (class i), alpha polypeptide (homo sapiens)",
"adh1b (bos taurus)"
] | Given the context 'There are important amino acid differences in the alcohol-binding site between the human class IV (sigma) and human class I (beta) alcohol dehydrogenases that appear to explain the high catalytic efficiency for all-trans-retinol, the high kcat for ethanol, and the low catalytic efficiency for secondary alcohols of sigma-ADH relative to beta 1-ADH.', answer the user's query. |
What is the biomedical concept corresponding to 'sigma-adh'? | [
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)",
"adh4 (homo sapiens) (alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens))"
] | [
"alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus)",
"alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c)"
] | Given the context 'There are important amino acid differences in the alcohol-binding site between the human class IV (sigma) and human class I (beta) alcohol dehydrogenases that appear to explain the high catalytic efficiency for all-trans-retinol, the high kcat for ethanol, and the low catalytic efficiency for secondary alcohols of sigma-ADH relative to beta 1-ADH.', answer the user's query. |
What is the biomedical concept corresponding to 'beta 1-adh'? | [
"adh1b (homo sapiens)",
"alcohol dehydrogenase 1b (class i), beta polypeptide (homo sapiens)"
] | [
"alcohol dehydrogenase 1b (class i), beta polypeptide (bos taurus)",
"adh1b (bos taurus)",
"adh1a (homo sapiens)",
"adh1b promoter (homo sapiens)"
] | Given the context 'There are important amino acid differences in the alcohol-binding site between the human class IV (sigma) and human class I (beta) alcohol dehydrogenases that appear to explain the high catalytic efficiency for all-trans-retinol, the high kcat for ethanol, and the low catalytic efficiency for secondary alcohols of sigma-ADH relative to beta 1-ADH.', answer the user's query. |
What is the biomedical concept corresponding to 'beta 1-adh'? | [
"adh1b (homo sapiens)",
"alcohol dehydrogenase 1b (class i), beta polypeptide (homo sapiens)"
] | [
"alcohol dehydrogenase 1b (class i), beta polypeptide (bos taurus)",
"adh1b (bos taurus)",
"adh1a (homo sapiens)",
"adh1b promoter (homo sapiens)"
] | Given the context 'For example, modeling the binding of all-trans-retinol in the human beta 1-ADH structure suggested that coordination of retinol to the active-site zinc is hindered by a loop from residues 114 to 120 that is at the entrance to the alcohol-binding site.', answer the user's query. |
What is the biomedical concept corresponding to 'sigma-adh'? | [
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens)",
"adh4 (homo sapiens) (alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (homo sapiens))"
] | [
"alcohol dehydrogenase adh1 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase 7 (class iv), mu or sigma polypeptide (rattus norvegicus)",
"alcohol dehydrogenase adh3 (saccharomyces cerevisiae s288c)",
"alcohol dehydrogenase adh2 (saccharomyces cerevisiae s288c)"
] | Given the context 'The deletion of Gly-117 in human sigma-ADH and a substitution of Leu for the bulky Tyr-110 appear to facilitate retinol access to the active-site zinc.', answer the user's query. |
What is the biomedical concept corresponding to 'type i acetyl-coa-carboxylase'? | [
"acetyl-coa carboxylase alpha (homo sapiens)",
"acc1 (homo sapiens) (acetyl-coa carboxylase alpha (homo sapiens))",
"acca (homo sapiens) (acetyl-coa carboxylase alpha (homo sapiens))",
"accalpha (homo sapiens)"
] | [
"acc-1 (homo sapiens)",
"acetyl-coa carboxylase beta (homo sapiens)",
"propionyl-coa carboxylase subunit alpha (homo sapiens)",
"acetoacetyl-coa synthetase (homo sapiens)"
] | Given the context 'The first 240 nucleotides in the 5' untranslated region of type I acetyl-CoA-carboxylase mRNA replace the first 100 nucleotides of the (G + C)-rich region of the 5' untranslated region of the type II mRNA.', answer the user's query. |
What is the biomedical concept corresponding to 'mu opiate receptor'? | [
"opioid receptor mu 1 (homo sapiens)"
] | [
"opioid related nociceptin receptor 1 (homo sapiens)",
"opioid receptor-like 1 (mus musculus)",
"nop (mus musculus) (opioid receptor-like 1 (mus musculus))",
"opioid receptor, mu 1 (rattus norvegicus)"
] | Given the context 'Human mu opiate receptor.', answer the user's query. |
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