query string | positive list | negative list | system string |
|---|---|---|---|
What is the biomedical concept corresponding to 'mu opiate receptor'? | [
"opioid receptor mu 1 (homo sapiens)"
] | [
"opioid related nociceptin receptor 1 (homo sapiens)",
"opioid receptor-like 1 (mus musculus)",
"nop (mus musculus) (opioid receptor-like 1 (mus musculus))",
"opioid receptor, mu 1 (rattus norvegicus)"
] | Given the context 'A human mu opiate receptor cDNA has been identified from a cerebral cortical cDNA library using sequences from the rat mu opiate receptor cDNA.', answer the user's query. |
What is the biomedical concept corresponding to 'mu opiate receptor'? | [
"opioid related nociceptin receptor 1 (rattus norvegicus)"
] | [
"opioid related nociceptin receptor 1 (homo sapiens)",
"opioid receptor mu 1 (homo sapiens)",
"opioid receptor-like 1 (mus musculus)",
"nop (mus musculus) (opioid receptor-like 1 (mus musculus))"
] | Given the context 'A human mu opiate receptor cDNA has been identified from a cerebral cortical cDNA library using sequences from the rat mu opiate receptor cDNA.', answer the user's query. |
What is the biomedical concept corresponding to 'mu opiate receptor'? | [
"opioid receptor mu 1 (homo sapiens)"
] | [
"opioid related nociceptin receptor 1 (homo sapiens)",
"opioid receptor-like 1 (mus musculus)",
"nop (mus musculus) (opioid receptor-like 1 (mus musculus))",
"opioid receptor, mu 1 (rattus norvegicus)"
] | Given the context 'The human mu opiate receptor (h mu OR1) shares 95% amino acid identity with the rat sequence.', answer the user's query. |
What is the biomedical concept corresponding to 'h mu or1'? | [
"m-or-1 (homo sapiens)"
] | [
"or-1 (mus musculus)",
"or1m1 (mus musculus)",
"or1o1 (mus musculus)",
"m-or-1 (mus musculus)"
] | Given the context 'The human mu opiate receptor (h mu OR1) shares 95% amino acid identity with the rat sequence.', answer the user's query. |
What is the biomedical concept corresponding to 'mu opiate receptor'? | [
"opioid related nociceptin receptor 1 (rattus norvegicus)"
] | [
"opioid related nociceptin receptor 1 (homo sapiens)",
"opioid receptor mu 1 (homo sapiens)",
"opioid receptor-like 1 (mus musculus)",
"nop (mus musculus) (opioid receptor-like 1 (mus musculus))"
] | Given the context 'The expressed mu OR1 recognized tested opiate drugs and opioid peptides in a sodium- and GTP-sensitive fashion with affinities virtually identical to those displayed by the rat mu opiate receptor.', answer the user's query. |
What is the biomedical concept corresponding to 'mu opiate receptor'? | [
"opioid related nociceptin receptor 1 (rattus norvegicus)"
] | [
"opioid related nociceptin receptor 1 (homo sapiens)",
"opioid receptor mu 1 (homo sapiens)",
"opioid receptor-like 1 (mus musculus)",
"nop (mus musculus) (opioid receptor-like 1 (mus musculus))"
] | Given the context 'Effects on cyclic AMP are similar to those noted for the rat mu opiate receptor.', answer the user's query. |
What is the biomedical concept corresponding to 'h mu or1'? | [
"m-or-1 (homo sapiens)"
] | [
"or-1 (mus musculus)",
"or1m1 (mus musculus)",
"or1o1 (mus musculus)",
"m-or-1 (mus musculus)"
] | Given the context 'An 18 kb genomic clone hybridizing with the h mu OR1 cDNA contains 63 and 489 bp exonic sequences flanked by splice donor/acceptor sequences.', answer the user's query. |
What is the biomedical concept corresponding to 'cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme a synthase'? | [
"3-hydroxy-3-methylglutaryl-coa synthase 1 (homo sapiens)"
] | [
"3-hydroxy-3-methylglutaryl-coa synthase 2 (homo sapiens)",
"3-hydroxy-3-methylglutaryl-coenzyme a synthase 1 (soluble) pseudogene (homo sapiens)",
"3-hydroxy-3-methylglutaryl-coa lyase (homo sapiens)",
"3-hydroxy-3-methylglutaryl-coenzyme a synthase 1 (mus musculus)"
] | Given the context 'Human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase: expression, purification, and characterization of recombinant wild-type and Cys129 mutant enzymes.
', answer the user's query. |
What is the biomedical concept corresponding to 'cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme a (hmg-coa) synthase'? | [
"3-hydroxy-3-methylglutaryl-coa synthase 1 (homo sapiens)",
"hmgcs (homo sapiens)"
] | [
"3-hydroxy-3-methylglutaryl-coa synthase 2 (homo sapiens)",
"3-hydroxy-3-methylglutaryl-coa lyase (homo sapiens)",
"3-hydroxy-3-methylglutaryl-coenzyme a synthase 1 (mus musculus)",
"3-hydroxy-3-methylglutaryl-coenzyme a synthase 1 (soluble) pseudogene (homo sapiens)"
] | Given the context 'A cDNA for the human cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase (EC 4.1.3.5) was subcloned and expressed from a T7-based vector in Escherichia coli.', answer the user's query. |
What is the biomedical concept corresponding to 'thyrotropin receptor'? | [
"tshr (homo sapiens)",
"thyroid stimulating hormone receptor (homo sapiens)"
] | [
"thyrotropin releasing hormone receptor (homo sapiens)",
"thyrotropin-releasing hormone receptor (bos taurus)",
"thyrotropin releasing hormone receptor (bos taurus)",
"thyrotropin releasing hormone receptor (gallus gallus)"
] | Given the context 'Germline mutations in the thyrotropin receptor gene cause non-autoimmune autosomal dominant hyperthyroidism.
', answer the user's query. |
What is the biomedical concept corresponding to 'thyrotropin receptor'? | [
"tshr (homo sapiens)",
"thyroid stimulating hormone receptor (homo sapiens)"
] | [
"thyrotropin releasing hormone receptor (homo sapiens)",
"thyrotropin-releasing hormone receptor (bos taurus)",
"thyrotropin releasing hormone receptor (bos taurus)",
"thyrotropin releasing hormone receptor (gallus gallus)"
] | Given the context 'The thyrotropin receptor (TSHR), a member of the large family of G protein-coupled receptors, controls both the function and growth of thyroid cells via stimulation of adenylyl cyclase.', answer the user's query. |
What is the biomedical concept corresponding to 'tshr'? | [
"tshr (homo sapiens)",
"thyroid stimulating hormone receptor (homo sapiens)"
] | [
"thyrotropin releasing hormone receptor (homo sapiens)",
"tshr (bos taurus)",
"thyrotropin-releasing hormone receptor (bos taurus)",
"trh-r (homo sapiens)"
] | Given the context 'The thyrotropin receptor (TSHR), a member of the large family of G protein-coupled receptors, controls both the function and growth of thyroid cells via stimulation of adenylyl cyclase.', answer the user's query. |
What is the biomedical concept corresponding to 'tshr'? | [
"tshr (homo sapiens)",
"thyroid stimulating hormone receptor (homo sapiens)"
] | [
"thyrotropin releasing hormone receptor (homo sapiens)",
"tshr (bos taurus)",
"thyrotropin-releasing hormone receptor (bos taurus)",
"trh-r (homo sapiens)"
] | Given the context 'We report two different mutations in the TSHR gene of affected members of two large pedigrees with non-autoimmune autosomal dominant hyperthyroidism (toxic thyroid hyperplasia), that involve residues in the third (Val509Ala) and seventh (Cys672Tyr) transmembrane segments.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'X-linked spastic paraplegia (SPG1), MASA syndrome and X-linked hydrocephalus result from mutations in the L1 gene.
', answer the user's query. |
What is the biomedical concept corresponding to 'neural cell adhesion molecule l1'? | [
"n-cam-l1 (homo sapiens)",
"l1cam (homo sapiens)",
"l1 cell adhesion molecule (homo sapiens)",
"ncam-l1 (homo sapiens)",
"n-caml1 (homo sapiens)"
] | [
"adhesion g protein-coupled receptor l1 (homo sapiens)",
"cell adhesion molecule l1 like (homo sapiens)",
"neural cell adhesion molecule 1 (homo sapiens)",
"cell adhesion molecule l1-like (rattus norvegicus)"
] | Given the context 'We have previously shown that X-linked hydrocephalus is caused by mutations in the gene for neural cell adhesion molecule L1 (L1CAM), an axonal glycoprotein involved in neuronal migration and differentiation.', answer the user's query. |
What is the biomedical concept corresponding to 'l1cam'? | [
"l1cam (homo sapiens)",
"n-cam-l1 (homo sapiens)",
"n-caml1 (homo sapiens)",
"l1 cell adhesion molecule (homo sapiens)",
"ncam-l1 (homo sapiens)"
] | [
"l1cam2 (homo sapiens)",
"l1cam (mus musculus)",
"cell adhesion molecule l1 like (homo sapiens)",
"l1cam (gallus gallus)"
] | Given the context 'We have previously shown that X-linked hydrocephalus is caused by mutations in the gene for neural cell adhesion molecule L1 (L1CAM), an axonal glycoprotein involved in neuronal migration and differentiation.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'Here we report mutations of the L1 gene in MASA syndrome and SPG1, in addition to HSAS families.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'Two of the HSAS mutations would abolish cell surface expression of L1 and represent the first functional null mutations in this disorder.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'Our results indicate that these three syndromes from part of a clinical spectrum resulting from a heterogeneous group of mutations in the L1 gene.', answer the user's query. |
What is the biomedical concept corresponding to 'bradykinin'? | [
"bk (homo sapiens)"
] | [
"kallikrein b1 (homo sapiens)",
"bradykinin (xenopus tropicalis)",
"kallikrein b1 (bos taurus)",
"bradykinin receptor b1 (homo sapiens)"
] | Given the context 'Bradykinin induces translocation of the protein kinase C isoforms alpha, epsilon, and zeta.
Bradykinin exerts a broad spectrum of cellular effects on different tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'bradykinin'? | [
"bk (homo sapiens)"
] | [
"kallikrein b1 (homo sapiens)",
"bradykinin (xenopus tropicalis)",
"kallikrein b1 (bos taurus)",
"bradykinin receptor b1 (homo sapiens)"
] | Given the context 'Bradykinin induces translocation of the protein kinase C isoforms alpha, epsilon, and zeta.
Bradykinin exerts a broad spectrum of cellular effects on different tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'b2 receptor'? | [
"b2r (homo sapiens)",
"bradykinin receptor b2 (homo sapiens)",
"bkr2 (homo sapiens)",
"bdkrb2 (homo sapiens)"
] | [
"b2ar (homo sapiens)",
"adrb2r (homo sapiens)",
"bkb1r (homo sapiens)",
"bb2r (homo sapiens)"
] | Given the context 'It is believed that these effects are predominantly mediated by the recently cloned B2 receptor.', answer the user's query. |
What is the biomedical concept corresponding to 'pkc isoforms alpha'? | [
"protein kinase c alpha (homo sapiens)",
"pkc-alpha (homo sapiens)",
"pkcalpha (homo sapiens)",
"pkca (homo sapiens)",
"prkaca (homo sapiens) (protein kinase c alpha (homo sapiens))"
] | [
"protein kinase camp-activated catalytic subunit alpha (homo sapiens)",
"prkaca (homo sapiens) (protein kinase camp-activated catalytic subunit alpha (homo sapiens))",
"protein kinase c, alpha (xenopus tropicalis)",
"prkaa (homo sapiens)"
] | Given the context 'Involvement of protein kinase C (PKC) was suggested and activation of the classical PKC isoforms alpha and beta was recently demonstrated.', answer the user's query. |
What is the biomedical concept corresponding to 'b2 receptor'? | [
"b2r (homo sapiens)",
"bradykinin receptor b2 (homo sapiens)",
"bkr2 (homo sapiens)",
"bdkrb2 (homo sapiens)"
] | [
"b2ar (homo sapiens)",
"adrb2r (homo sapiens)",
"bkb1r (homo sapiens)",
"bb2r (homo sapiens)"
] | Given the context 'The aim of the present study was to investigate whether the B2 receptor also activates new (delta, epsilon) and atypical (zeta) PKC isoforms.', answer the user's query. |
What is the biomedical concept corresponding to 'b2 receptor'? | [
"b2r (homo sapiens)",
"bradykinin receptor b2 (homo sapiens)",
"bkr2 (homo sapiens)",
"bdkrb2 (homo sapiens)"
] | [
"b2ar (homo sapiens)",
"adrb2r (homo sapiens)",
"bkb1r (homo sapiens)",
"bb2r (homo sapiens)"
] | Given the context 'To investigate this, chinese hamster ovary (CHO) cells, stably transfected with human B2 receptor, were used.', answer the user's query. |
What is the biomedical concept corresponding to 'bradykinin'? | [
"bk (homo sapiens)"
] | [
"kallikrein b1 (homo sapiens)",
"bradykinin (xenopus tropicalis)",
"kallikrein b1 (bos taurus)",
"bradykinin receptor b1 (homo sapiens)"
] | Given the context 'Stimulation of the cells with bradykinin resulted in a rapid (30-60 s) translocation of the PKC isoforms alpha, epsilon, and zeta.', answer the user's query. |
What is the biomedical concept corresponding to 'pkc delta'? | [
"protein kinase c delta (homo sapiens)",
"npkc-delta (homo sapiens)",
"pkcd (homo sapiens)",
"prkcd (homo sapiens)"
] | [
"protein kinase c delta (drosophila melanogaster)",
"protein kinase c delta (xenopus tropicalis)",
"protein kinase c delta (bos taurus)",
"delta pkc (drosophila melanogaster)"
] | Given the context 'Translocation of PKC delta was not detected.', answer the user's query. |
What is the biomedical concept corresponding to 'bradykinin'? | [
"bk (homo sapiens)"
] | [
"kallikrein b1 (homo sapiens)",
"bradykinin (xenopus tropicalis)",
"kallikrein b1 (bos taurus)",
"bradykinin receptor b1 (homo sapiens)"
] | Given the context 'The effect of bradykinin was reduced by simultaneous addition of the receptor antagonist HOE 140, a bradykinin-related decapeptide.', answer the user's query. |
What is the biomedical concept corresponding to 'bradykinin'? | [
"bk (homo sapiens)"
] | [
"kallikrein b1 (homo sapiens)",
"bradykinin (xenopus tropicalis)",
"kallikrein b1 (bos taurus)",
"bradykinin receptor b1 (homo sapiens)"
] | Given the context 'The effect of bradykinin was reduced by simultaneous addition of the receptor antagonist HOE 140, a bradykinin-related decapeptide.', answer the user's query. |
What is the biomedical concept corresponding to 'b2 receptor'? | [
"b2r (homo sapiens)",
"bradykinin receptor b2 (homo sapiens)",
"bkr2 (homo sapiens)",
"bdkrb2 (homo sapiens)"
] | [
"b2ar (homo sapiens)",
"adrb2r (homo sapiens)",
"bkb1r (homo sapiens)",
"bb2r (homo sapiens)"
] | Given the context 'The data show that the B2 receptor in this cell model is able to activate, in addition to the classical PKC isoform alpha, the new PKC isoform epsilon and the atypical PKC isoform zeta.', answer the user's query. |
What is the biomedical concept corresponding to 'pkc isoform alpha'? | [
"protein kinase c alpha (homo sapiens)",
"pkc-alpha (homo sapiens)",
"pkcalpha (homo sapiens)",
"pkca (homo sapiens)",
"prkaca (homo sapiens) (protein kinase c alpha (homo sapiens))"
] | [
"protein kinase camp-activated catalytic subunit alpha (homo sapiens)",
"prkaa (homo sapiens)",
"prkaca (homo sapiens) (protein kinase camp-activated catalytic subunit alpha (homo sapiens))",
"pkn-alpha (homo sapiens)"
] | Given the context 'The data show that the B2 receptor in this cell model is able to activate, in addition to the classical PKC isoform alpha, the new PKC isoform epsilon and the atypical PKC isoform zeta.', answer the user's query. |
What is the biomedical concept corresponding to 'pkc isoform epsilon'? | [
"protein kinase c epsilon (homo sapiens)",
"npkc-epsilon (homo sapiens)",
"pkce (homo sapiens)"
] | [
"protein kinase c eta (homo sapiens)",
"protein kinase c epsilon (xenopus tropicalis)",
"protein kinase c, epsilon (mus musculus)",
"protein kinase c epsilon (bos taurus)"
] | Given the context 'The data show that the B2 receptor in this cell model is able to activate, in addition to the classical PKC isoform alpha, the new PKC isoform epsilon and the atypical PKC isoform zeta.', answer the user's query. |
What is the biomedical concept corresponding to 'pkc isoform zeta'? | [
"protein kinase c zeta (homo sapiens)",
"pkc-zeta (homo sapiens)"
] | [
"protein kinase c zeta (xenopus tropicalis)",
"protein kinase c zeta (bos taurus)",
"protein kinase c, zeta (danio rerio)",
"pkc-zeta (xenopus tropicalis)"
] | Given the context 'The data show that the B2 receptor in this cell model is able to activate, in addition to the classical PKC isoform alpha, the new PKC isoform epsilon and the atypical PKC isoform zeta.', answer the user's query. |
What is the biomedical concept corresponding to 'b2 receptor'? | [
"b2r (homo sapiens)",
"bradykinin receptor b2 (homo sapiens)",
"bkr2 (homo sapiens)",
"bdkrb2 (homo sapiens)"
] | [
"b2ar (homo sapiens)",
"adrb2r (homo sapiens)",
"bkb1r (homo sapiens)",
"bb2r (homo sapiens)"
] | Given the context 'In this cell system similar results on PKC alpha, epsilon, and zeta were observed, suggesting that all three PKC isoforms are involved in signal transduction of the B2 receptor.', answer the user's query. |
What is the biomedical concept corresponding to 'dlk'? | [
"dlk-1 (homo sapiens)",
"dlk1 (homo sapiens)"
] | [
"dlk-2 (homo sapiens)",
"dlk/zpk (drosophila melanogaster)",
"dlak (drosophila melanogaster)",
"dlk (drosophila melanogaster) (leucokinin (drosophila melanogaster))"
] | Given the context 'A novel circulating human epidermal-growth-factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2.
', answer the user's query. |
What is the biomedical concept corresponding to 'pg2'? | [
"pg2 (homo sapiens)"
] | [
"pghs-2 (homo sapiens)",
"pgdp2 (homo sapiens)",
"pgap2 (homo sapiens)",
"pgm2 (homo sapiens)"
] | Given the context 'A novel circulating human epidermal-growth-factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2.
', answer the user's query. |
What is the biomedical concept corresponding to 'dlk'? | [
"dlk-1 (homo sapiens)",
"dlk1 (homo sapiens)"
] | [
"dlk-2 (homo sapiens)",
"dlk/zpk (drosophila melanogaster)",
"dlak (drosophila melanogaster)",
"dlk (drosophila melanogaster) (leucokinin (drosophila melanogaster))"
] | Given the context 'Alignment to the translated sequences of Mus. musculus dlk and human dlk revealed 86% and 99% identity, respectively, to a 259-amino-acid residue overlap, and this high similarity extends with minor corrections to the human adrenal-specific mRNA, pG2 as well.', answer the user's query. |
What is the biomedical concept corresponding to 'dlk'? | [
"dlk-1 (homo sapiens)",
"dlk1 (homo sapiens)"
] | [
"dlk-2 (homo sapiens)",
"dlk/zpk (drosophila melanogaster)",
"dlak (drosophila melanogaster)",
"dlk (drosophila melanogaster) (leucokinin (drosophila melanogaster))"
] | Given the context 'Alignment to the translated sequences of Mus. musculus dlk and human dlk revealed 86% and 99% identity, respectively, to a 259-amino-acid residue overlap, and this high similarity extends with minor corrections to the human adrenal-specific mRNA, pG2 as well.', answer the user's query. |
What is the biomedical concept corresponding to 'pg2'? | [
"pg2 (homo sapiens)"
] | [
"pghs-2 (homo sapiens)",
"pgdp2 (homo sapiens)",
"pgap2 (homo sapiens)",
"pgm2 (homo sapiens)"
] | Given the context 'Alignment to the translated sequences of Mus. musculus dlk and human dlk revealed 86% and 99% identity, respectively, to a 259-amino-acid residue overlap, and this high similarity extends with minor corrections to the human adrenal-specific mRNA, pG2 as well.', answer the user's query. |
What is the biomedical concept corresponding to 'dlk'? | [
"dlk-1 (homo sapiens)",
"dlk1 (homo sapiens)"
] | [
"dlk-2 (homo sapiens)",
"dlk/zpk (drosophila melanogaster)",
"dlak (drosophila melanogaster)",
"dlk (drosophila melanogaster) (leucokinin (drosophila melanogaster))"
] | Given the context 'Our findings suggest that FA1 is synthesized as a membrane anchored protein and released into the circulation after enzymic cleavage, and that circulating FA1 represents the post-translationally modified gene product of human dlk which, in turn, is identical to human adrenal-specific mRNA pG2.', answer the user's query. |
What is the biomedical concept corresponding to 'pg2'? | [
"pg2 (homo sapiens)"
] | [
"pghs-2 (homo sapiens)",
"pgdp2 (homo sapiens)",
"pgap2 (homo sapiens)",
"pgm2 (homo sapiens)"
] | Given the context 'Our findings suggest that FA1 is synthesized as a membrane anchored protein and released into the circulation after enzymic cleavage, and that circulating FA1 represents the post-translationally modified gene product of human dlk which, in turn, is identical to human adrenal-specific mRNA pG2.', answer the user's query. |
What is the biomedical concept corresponding to 'hdh ii/ku'? | [
"kub2 (homo sapiens)"
] | [
"atp-dependent dna helicase 2 subunit ku70 (glycine max)",
"atp-dependent dna helicase ii subunit 2;ku c-terminal domain-containing protein;ku_pk_bind domain-containing protein (caenorhabditis elegans)",
"kub1 (homo sapiens)",
"atp-dependent dna helicase 2 subunit ku80 (glycine max)"
] | Given the context 'Recombinant HDH II/Ku protein expressed in and purified from Escherichia coli cells showed DNA binding and helicase activities indistinguishable from those of the isolated protein.', answer the user's query. |
What is the biomedical concept corresponding to 'hdh ii/ku'? | [
"kub2 (homo sapiens)"
] | [
"atp-dependent dna helicase 2 subunit ku70 (glycine max)",
"atp-dependent dna helicase ii subunit 2;ku c-terminal domain-containing protein;ku_pk_bind domain-containing protein (caenorhabditis elegans)",
"kub1 (homo sapiens)",
"atp-dependent dna helicase 2 subunit ku80 (glycine max)"
] | Given the context 'The exclusively nuclear location of HDH II/Ku antigen, its highly specific affinity for double-stranded DNA, its abundance and its newly demonstrated ability to unwind exclusively DNA duplexes, point to an additional, if still unclear, role for this molecule in DNA metabolism.', answer the user's query. |
What is the biomedical concept corresponding to 'cytokine (ik)'? | [
"ik cytokine (homo sapiens)",
"ik (homo sapiens) (ik cytokine (homo sapiens))"
] | [
"ik cytokine (mus musculus)",
"ik cytokine (xenopus tropicalis)",
"interferon kappa (homo sapiens)",
"ifnk (homo sapiens)"
] | Given the context 'A new cytokine (IK) down-regulating HLA class II: monoclonal antibodies, cloning and chromosome localization.
', answer the user's query. |
What is the biomedical concept corresponding to 'ik factor'? | [
"ik (homo sapiens) (ik cytokine (homo sapiens))",
"ik cytokine (homo sapiens)"
] | [
"iklf (homo sapiens)",
"ikzf1 (homo sapiens)",
"ik-1 (xenopus tropicalis)",
"ik-1 (xenopus laevis) (ikaros family zinc finger 1 l homeolog (xenopus laevis))"
] | Given the context 'We have purified a cytokine (IK factor, 19 kDa) secreted by the leukemic cell line K562 and several cancer cells, which inhibits HLA Class II antigen induction by IFN-gamma.', answer the user's query. |
What is the biomedical concept corresponding to 'ifn-gamma'? | [
"interferon gamma (homo sapiens)"
] | [
"interferon gamma (xenopus tropicalis)",
"interferon gamma (mus musculus)",
"gmf-gamma (homo sapiens)",
"interleukin 36 gamma (homo sapiens)"
] | Given the context 'We have purified a cytokine (IK factor, 19 kDa) secreted by the leukemic cell line K562 and several cancer cells, which inhibits HLA Class II antigen induction by IFN-gamma.', answer the user's query. |
What is the biomedical concept corresponding to 'ik'? | [
"ik (homo sapiens) (ik cytokine (homo sapiens))",
"ik cytokine (homo sapiens)"
] | [
"ik (mus musculus)",
"ik1 (mus musculus)",
"ikki (homo sapiens)",
"ik (bos taurus)"
] | Given the context 'We produced specific mAbs which antagonize the biological effect of IK in colon carcinoma Colo 205 cells induced to express HLA-DR molecules by IFN-gamma.', answer the user's query. |
What is the biomedical concept corresponding to 'ifn-gamma'? | [
"interferon gamma (homo sapiens)"
] | [
"interferon gamma (xenopus tropicalis)",
"interferon gamma (mus musculus)",
"gmf-gamma (homo sapiens)",
"interleukin 36 gamma (homo sapiens)"
] | Given the context 'We produced specific mAbs which antagonize the biological effect of IK in colon carcinoma Colo 205 cells induced to express HLA-DR molecules by IFN-gamma.', answer the user's query. |
What is the biomedical concept corresponding to 'ik factor'? | [
"ik (homo sapiens) (ik cytokine (homo sapiens))",
"ik cytokine (homo sapiens)"
] | [
"iklf (homo sapiens)",
"ikzf1 (homo sapiens)",
"ik-1 (xenopus tropicalis)",
"ik-1 (xenopus laevis) (ikaros family zinc finger 1 l homeolog (xenopus laevis))"
] | Given the context 'Moreover, in Colo 205, HLA-DR can also be induced by the protein synthesis inhibitor Cycloheximide (0.1 micrograms ml-1); and addition of IK factor almost completely abolishes HLA class II expression.', answer the user's query. |
What is the biomedical concept corresponding to 'ik'? | [
"ik (homo sapiens) (ik cytokine (homo sapiens))",
"ik cytokine (homo sapiens)"
] | [
"ik (mus musculus)",
"ik1 (mus musculus)",
"ikki (homo sapiens)",
"ik (bos taurus)"
] | Given the context 'IK gene localization shows that it maps on chromosome 2p15-p14.', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', answer the user's query. |
What is the biomedical concept corresponding to 'btk'? | [
"btk (homo sapiens)",
"bruton tyrosine kinase (homo sapiens)"
] | [
"btk (bos taurus)",
"bruton tyrosine kinase (bos taurus)",
"btkl (homo sapiens)",
"blk proto-oncogene, src family tyrosine kinase (bos taurus)"
] | Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', answer the user's query. |
What is the biomedical concept corresponding to 'itk'? | [
"itk (homo sapiens)",
"il2 inducible t cell kinase (homo sapiens)"
] | [
"itk (bos taurus)",
"itk (mus musculus)",
"itk (gallus gallus)",
"itk (xenopus tropicalis)"
] | Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', answer the user's query. |
What is the biomedical concept corresponding to 'tec'? | [
"tec protein tyrosine kinase (homo sapiens)",
"tec (homo sapiens) (tec protein tyrosine kinase (homo sapiens))"
] | [
"teck (homo sapiens)",
"tec (homo sapiens) (transient erythroblastopenia of childhood (homo sapiens))",
"tec (xenopus tropicalis) (tec protein tyrosine kinase (xenopus tropicalis))",
"tecta (homo sapiens)"
] | Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', answer the user's query. |
What is the biomedical concept corresponding to 'txk'? | [
"txk (homo sapiens)",
"txk tyrosine kinase (homo sapiens)"
] | [
"txk (bos taurus)",
"txk tyrosine kinase (bos taurus)",
"txk (mus musculus)",
"txk tyrosine kinase (mus musculus)"
] | Given the context 'BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2.
', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'The Bmx sequence was identified and cloned during our search for novel tyrosine kinase genes expressed in human bone marrow cells.', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', answer the user's query. |
What is the biomedical concept corresponding to 'btk'? | [
"btk (homo sapiens)",
"bruton tyrosine kinase (homo sapiens)"
] | [
"btk (bos taurus)",
"bruton tyrosine kinase (bos taurus)",
"btkl (homo sapiens)",
"blk proto-oncogene, src family tyrosine kinase (bos taurus)"
] | Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', answer the user's query. |
What is the biomedical concept corresponding to 'itk'? | [
"itk (homo sapiens)",
"il2 inducible t cell kinase (homo sapiens)"
] | [
"itk (bos taurus)",
"itk (mus musculus)",
"itk (gallus gallus)",
"itk (xenopus tropicalis)"
] | Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', answer the user's query. |
What is the biomedical concept corresponding to 'tec'? | [
"tec protein tyrosine kinase (homo sapiens)",
"tec (homo sapiens) (tec protein tyrosine kinase (homo sapiens))"
] | [
"teck (homo sapiens)",
"tec (homo sapiens) (transient erythroblastopenia of childhood (homo sapiens))",
"tec (xenopus tropicalis) (tec protein tyrosine kinase (xenopus tropicalis))",
"tecta (homo sapiens)"
] | Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', answer the user's query. |
What is the biomedical concept corresponding to 'txk'? | [
"txk (homo sapiens)",
"txk tyrosine kinase (homo sapiens)"
] | [
"txk (bos taurus)",
"txk tyrosine kinase (bos taurus)",
"txk (mus musculus)",
"txk tyrosine kinase (mus musculus)"
] | Given the context 'Bmx cDNA comprises a long open reading frame of 675 amino acids, containing one SH3, one SH2 and one tyrosine kinase domain, which are about 70% identical with Btk, Itk and Tec and somewhat less with Txk tyrosine kinase sequences.', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'The 2.7 kb Bmx mRNA was expressed in endothelial cells and several human tissues by Northern blotting and an 80 kD Bmx polypeptide was detected in human endothelial cells.', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'The 2.7 kb Bmx mRNA was expressed in endothelial cells and several human tissues by Northern blotting and an 80 kD Bmx polypeptide was detected in human endothelial cells.', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'Immunoprecipitates of COS cells transfected with a Bmx expression vector and NIH3T3 cells expressing a Bmx retrovirus contained a tyrosyl phosphorylated Bmx polypeptide of similar molecular weight.', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'Immunoprecipitates of COS cells transfected with a Bmx expression vector and NIH3T3 cells expressing a Bmx retrovirus contained a tyrosyl phosphorylated Bmx polypeptide of similar molecular weight.', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'Immunoprecipitates of COS cells transfected with a Bmx expression vector and NIH3T3 cells expressing a Bmx retrovirus contained a tyrosyl phosphorylated Bmx polypeptide of similar molecular weight.', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'The BMX gene was located in chromosomal band Xp22.2 between the DXS197 and DXS207 loci.', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia.', answer the user's query. |
What is the biomedical concept corresponding to 'btk'? | [
"btk (homo sapiens)",
"bruton tyrosine kinase (homo sapiens)"
] | [
"btk (bos taurus)",
"bruton tyrosine kinase (bos taurus)",
"btkl (homo sapiens)",
"blk proto-oncogene, src family tyrosine kinase (bos taurus)"
] | Given the context 'Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia.', answer the user's query. |
What is the biomedical concept corresponding to 'bmx'? | [
"bmx (homo sapiens)",
"bmx non-receptor tyrosine kinase (homo sapiens)"
] | [
"bmx (mus musculus)",
"bmx (gallus gallus)",
"bmx (bos taurus)",
"bmnx (mus musculus)"
] | Given the context 'The BMX gene thus encodes a novel nonreceptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells.', answer the user's query. |
What is the biomedical concept corresponding to 'brk'? | [
"brk (homo sapiens)"
] | [
"brk-3 (homo sapiens)",
"brk1 (homo sapiens)",
"brpk (homo sapiens)",
"brks (homo sapiens)"
] | Given the context 'Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours.
', answer the user's query. |
What is the biomedical concept corresponding to 'brk'? | [
"brk (homo sapiens)"
] | [
"brk-3 (homo sapiens)",
"brk1 (homo sapiens)",
"brpk (homo sapiens)",
"brks (homo sapiens)"
] | Given the context 'Using a polymerase chain reaction based differential screening approach, we have isolated and characterised a cDNA from a human metastatic breast tumour representing a novel protein tyrosine kinase (brk).', answer the user's query. |
What is the biomedical concept corresponding to 'brk'? | [
"brk (homo sapiens)"
] | [
"brk-3 (homo sapiens)",
"brk1 (homo sapiens)",
"brpk (homo sapiens)",
"brks (homo sapiens)"
] | Given the context 'Sequencing of brk cDNAs isolated from T-47D and MCF-7 human breast tumour cell lines indicate that they encode a protein with the features of a novel nonreceptor tyrosine kinase, including amino terminal SH3 and SH2 domains.', answer the user's query. |
What is the biomedical concept corresponding to 'brk'? | [
"brk (homo sapiens)"
] | [
"brk-3 (homo sapiens)",
"brk1 (homo sapiens)",
"brpk (homo sapiens)",
"brks (homo sapiens)"
] | Given the context 'When synthesised in recombinant baculovirus and bacterial expression systems, brk protein products are capable of autophosphorylation on tyrosine residues.', answer the user's query. |
What is the biomedical concept corresponding to 'brk'? | [
"brk (homo sapiens)"
] | [
"brk-3 (homo sapiens)",
"brk1 (homo sapiens)",
"brpk (homo sapiens)",
"brks (homo sapiens)"
] | Given the context 'Initial expression studies have detected low levels of brk transcripts in some human breast tumours and breast tumour cell lines, but not in normal breast tissue.', answer the user's query. |
What is the biomedical concept corresponding to 'pc4'? | [
"pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens))"
] | [
"pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus))",
"pc4 (homo sapiens) (proprotein convertase subtilisin/kexin type 4 (homo sapiens))",
"pc4-like (drosophila melanogaster)",
"pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus))"
] | Given the context 'Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes.
', answer the user's query. |
What is the biomedical concept corresponding to 'pc4'? | [
"pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens))"
] | [
"pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus))",
"pc4 (homo sapiens) (proprotein convertase subtilisin/kexin type 4 (homo sapiens))",
"pc4-like (drosophila melanogaster)",
"pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus))"
] | Given the context 'A novel positive cofactor (PC4) purified from the human USA fraction effected a marked enhancement (up to 85-fold) of GAL4-AH-dependent transcription in conjunction with TFIID and other general factors.', answer the user's query. |
What is the biomedical concept corresponding to 'gal4'? | [
"gal4 (homo sapiens)"
] | [
"galactose-responsive transcription factor gal4 (saccharomyces cerevisiae s288c)",
"gal4 (saccharomyces cerevisiae s288c)",
"gal4 (xenopus tropicalis)",
"gal4 (candida albicans sc5314)"
] | Given the context 'A novel positive cofactor (PC4) purified from the human USA fraction effected a marked enhancement (up to 85-fold) of GAL4-AH-dependent transcription in conjunction with TFIID and other general factors.', answer the user's query. |
What is the biomedical concept corresponding to 'pc4'? | [
"pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens))"
] | [
"pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus))",
"pc4 (homo sapiens) (proprotein convertase subtilisin/kexin type 4 (homo sapiens))",
"pc4-like (drosophila melanogaster)",
"pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus))"
] | Given the context 'Isolation of a corresponding cDNA identified PC4 as a 127 residue single-stranded DNA-binding protein with serine-rich regions near the N-terminus.', answer the user's query. |
What is the biomedical concept corresponding to 'pc4'? | [
"pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens))"
] | [
"pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus))",
"pc4 (homo sapiens) (proprotein convertase subtilisin/kexin type 4 (homo sapiens))",
"pc4-like (drosophila melanogaster)",
"pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus))"
] | Given the context 'Recombinant PC4 was functionally equivalent to native PC4, and both proteins markedly enhanced activation by diverse activation domains fused to the DNA-binding domain of GAL4.', answer the user's query. |
What is the biomedical concept corresponding to 'pc4'? | [
"pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens))"
] | [
"pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus))",
"pc4 (homo sapiens) (proprotein convertase subtilisin/kexin type 4 (homo sapiens))",
"pc4-like (drosophila melanogaster)",
"pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus))"
] | Given the context 'Recombinant PC4 was functionally equivalent to native PC4, and both proteins markedly enhanced activation by diverse activation domains fused to the DNA-binding domain of GAL4.', answer the user's query. |
What is the biomedical concept corresponding to 'gal4'? | [
"gal4 (homo sapiens)"
] | [
"galactose-responsive transcription factor gal4 (saccharomyces cerevisiae s288c)",
"gal4 (saccharomyces cerevisiae s288c)",
"gal4 (xenopus tropicalis)",
"gal4 (candida albicans sc5314)"
] | Given the context 'Recombinant PC4 was functionally equivalent to native PC4, and both proteins markedly enhanced activation by diverse activation domains fused to the DNA-binding domain of GAL4.', answer the user's query. |
What is the biomedical concept corresponding to 'pc4'? | [
"pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens))"
] | [
"pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus))",
"pc4 (homo sapiens) (proprotein convertase subtilisin/kexin type 4 (homo sapiens))",
"pc4-like (drosophila melanogaster)",
"pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus))"
] | Given the context 'Recombinant PC4 interacted independently both with free or DNA-bound VP16 activation domains and with free or DNA-bound TFIIA-TBP complexes (but not with TBP alone).', answer the user's query. |
What is the biomedical concept corresponding to 'pc4'? | [
"pc4 (homo sapiens) (sub1 regulator of transcription (homo sapiens))"
] | [
"pc4 (mus musculus) (sub1 homolog, transcriptional regulator (mus musculus))",
"pc4 (homo sapiens) (proprotein convertase subtilisin/kexin type 4 (homo sapiens))",
"pc4-like (drosophila melanogaster)",
"pc4 (mus musculus) (proprotein convertase subtilisin/kexin type 4 (mus musculus))"
] | Given the context 'These results indicate that PC4 is a general coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery.', answer the user's query. |
What is the biomedical concept corresponding to 'coproporphyrinogen oxidase'? | [
"coproporphyrinogen oxidase (homo sapiens)",
"cpo (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cox (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cpx (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))"
] | [
"coproporphyrinogen oxidase (drosophila melanogaster)",
"coproporphyrinogen oxidase (glycine max)",
"protoporphyrinogen oxidase (homo sapiens)",
"coproporphyrinogen oxidase (danio rerio)"
] | Given the context 'Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase.
Coproporphyrinogen oxidase (EC 1.3.3.3) catalyzes the sixth step in the heme biosynthetic pathway, the oxidation of coproporphyrinogen III to protoporphyrinogen IX.', answer the user's query. |
What is the biomedical concept corresponding to 'coproporphyrinogen oxidase'? | [
"coproporphyrinogen oxidase (homo sapiens)",
"cpo (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cox (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cpx (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))"
] | [
"coproporphyrinogen oxidase (drosophila melanogaster)",
"coproporphyrinogen oxidase (glycine max)",
"protoporphyrinogen oxidase (homo sapiens)",
"coproporphyrinogen oxidase (danio rerio)"
] | Given the context 'Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase.
Coproporphyrinogen oxidase (EC 1.3.3.3) catalyzes the sixth step in the heme biosynthetic pathway, the oxidation of coproporphyrinogen III to protoporphyrinogen IX.', answer the user's query. |
What is the biomedical concept corresponding to 'coproporphyrinogen oxidase'? | [
"coproporphyrinogen oxidase (homo sapiens)",
"cpo (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cox (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cpx (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))"
] | [
"coproporphyrinogen oxidase (drosophila melanogaster)",
"coproporphyrinogen oxidase (glycine max)",
"protoporphyrinogen oxidase (homo sapiens)",
"coproporphyrinogen oxidase (danio rerio)"
] | Given the context 'The sequence of the cDNA and predicted amino acid sequence of the human coproporphyrinogen oxidase are presented.', answer the user's query. |
What is the biomedical concept corresponding to 'coproporphyrinogen oxidase'? | [
"coproporphyrinogen oxidase (homo sapiens)",
"cpo (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cox (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cpx (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))"
] | [
"coproporphyrinogen oxidase (drosophila melanogaster)",
"coproporphyrinogen oxidase (glycine max)",
"protoporphyrinogen oxidase (homo sapiens)",
"coproporphyrinogen oxidase (danio rerio)"
] | Given the context 'The human protein sequence contains a region completely homologous to that we obtained by sequencing an 11-amino acid peptide fragment from purified murine liver coproporphyrinogen oxidase.', answer the user's query. |
What is the biomedical concept corresponding to 'coproporphyrinogen oxidase'? | [
"coproporphyrinogen oxidase (homo sapiens)",
"cpo (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cox (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cpx (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))"
] | [
"coproporphyrinogen oxidase (drosophila melanogaster)",
"coproporphyrinogen oxidase (glycine max)",
"protoporphyrinogen oxidase (homo sapiens)",
"coproporphyrinogen oxidase (danio rerio)"
] | Given the context 'Results of Southern blotting were consistent with the presence of a single human coproporphyrinogen oxidase gene, and Northern blotting demonstrated one transcript of similar size in erythroid and nonerythroid cell lines.', answer the user's query. |
What is the biomedical concept corresponding to 'coproporphyrinogen oxidase'? | [
"coproporphyrinogen oxidase (homo sapiens)",
"cpo (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cox (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))",
"cpx (homo sapiens) (coproporphyrinogen oxidase (homo sapiens))"
] | [
"coproporphyrinogen oxidase (drosophila melanogaster)",
"coproporphyrinogen oxidase (glycine max)",
"protoporphyrinogen oxidase (homo sapiens)",
"coproporphyrinogen oxidase (danio rerio)"
] | Given the context 'Expression of the cDNA coding for the putative mature human coproporphyrinogen oxidase in Escherichia coli resulted in a 17-fold increase in coproporphyrinogen activity over endogenous activity.', answer the user's query. |
What is the biomedical concept corresponding to 'he2'? | [
"he2c (homo sapiens)"
] | [
"hes2 (homo sapiens)",
"hey2 (homo sapiens)",
"he3b (homo sapiens)",
"he1 (homo sapiens)"
] | Given the context 'Molecular cloning and characterization of a novel human sperm antigen (HE2) specifically expressed in the proximal epididymis.
', answer the user's query. |
What is the biomedical concept corresponding to 'he2'? | [
"he2c (homo sapiens)"
] | [
"hes2 (homo sapiens)",
"hey2 (homo sapiens)",
"he3b (homo sapiens)",
"he1 (homo sapiens)"
] | Given the context 'A novel human cDNA encoding a small secretory glycopeptide specifically expressed within the caput and proximal corpus regions of the human epididymis, HE2, has been cloned and sequenced.', answer the user's query. |
What is the biomedical concept corresponding to 'he2'? | [
"he2c (homo sapiens)"
] | [
"hes2 (homo sapiens)",
"hey2 (homo sapiens)",
"he3b (homo sapiens)",
"he1 (homo sapiens)"
] | Given the context 'This recombinant HE2 protein, as well as an oligopeptide deduced from the open-reading frame, was used to raise polyclonal antisera.', answer the user's query. |
What is the biomedical concept corresponding to 'he2'? | [
"he2c (homo sapiens)"
] | [
"hes2 (homo sapiens)",
"hey2 (homo sapiens)",
"he3b (homo sapiens)",
"he1 (homo sapiens)"
] | Given the context 'Immunohistochemistry and immunofluorescence showed that the predicted HE2 peptide is present in the epididymal epithelium and on the sperm surface, where it adopts a typical antigenic pattern with a subacrosomal equatorial distribution on the sperm head.', answer the user's query. |
What is the biomedical concept corresponding to 'nicotinamide n-methyltransferase'? | [
"nicotinamide n-methyltransferase (homo sapiens)",
"nnmt (homo sapiens)"
] | [
"nicotinamide n-methyltransferase (mus musculus)",
"nicotinamide n-methyltransferase (rattus norvegicus)",
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nmt1 (homo sapiens)"
] | Given the context 'Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines.', answer the user's query. |
What is the biomedical concept corresponding to 'nicotinamide n-methyltransferase'? | [
"nicotinamide n-methyltransferase (homo sapiens)",
"nnmt (homo sapiens)"
] | [
"nicotinamide n-methyltransferase (mus musculus)",
"nicotinamide n-methyltransferase (rattus norvegicus)",
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))",
"nmt1 (homo sapiens)"
] | Given the context 'Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (mus musculus)",
"nnmt (rattus norvegicus)",
"nicotinamide n-methyltransferase (mus musculus)",
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))"
] | Given the context 'Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization.
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide and other pyridines.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (mus musculus)",
"nnmt (rattus norvegicus)",
"nicotinamide n-methyltransferase (mus musculus)",
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))"
] | Given the context 'Human liver NNMT activity has a bimodal frequency distribution, an observation which raises the possibility that this enzyme activity might be regulated by a genetic polymorphism, a polymorphism that could have functional implications for individual differences in drug and xenobiotic toxicity.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (mus musculus)",
"nnmt (rattus norvegicus)",
"nicotinamide n-methyltransferase (mus musculus)",
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))"
] | Given the context 'As a first step toward testing that hypothesis, we set out to clone and express a cDNA for human liver NNMT.', answer the user's query. |
What is the biomedical concept corresponding to 'nnmt'? | [
"nnmt (homo sapiens)",
"nicotinamide n-methyltransferase (homo sapiens)"
] | [
"nnmt (mus musculus)",
"nnmt (rattus norvegicus)",
"nicotinamide n-methyltransferase (mus musculus)",
"nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))"
] | Given the context 'Human liver NNMT was partially purified, photoaffinity-labeled, subjected to limited proteolysis, and partial amino acid sequence information was obtained.', answer the user's query. |
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