query string | positive list | negative list | system string |
|---|---|---|---|
What is the biomedical concept corresponding to 'hbnpi'? | [
"bnpi (homo sapiens)"
] | [
"nprbi (homo sapiens)",
"impnb (homo sapiens)",
"npi (homo sapiens)",
"pnpi (homo sapiens)"
] | Given the context 'The level of hBNPI mRNA is quite low in fetal compared with adult human brain, suggesting developmental regulation of hBNPI gene expression.', answer the user's query. |
What is the biomedical concept corresponding to 'hbnpi'? | [
"bnpi (homo sapiens)"
] | [
"nprbi (homo sapiens)",
"impnb (homo sapiens)",
"npi (homo sapiens)",
"pnpi (homo sapiens)"
] | Given the context 'Southern analyses of nine eukaryotic genomic DNAs probed under stringent conditions with hBNPI cDNA revealed that the hBNPI gene is highly conserved during vertebrate evolution and that each gene is most likely present as a single copy.', answer the user's query. |
What is the biomedical concept corresponding to 'hbnpi'? | [
"bnpi (homo sapiens)"
] | [
"nprbi (homo sapiens)",
"impnb (homo sapiens)",
"npi (homo sapiens)",
"pnpi (homo sapiens)"
] | Given the context 'Southern analyses of nine eukaryotic genomic DNAs probed under stringent conditions with hBNPI cDNA revealed that the hBNPI gene is highly conserved during vertebrate evolution and that each gene is most likely present as a single copy.', answer the user's query. |
What is the biomedical concept corresponding to 'hbnpi'? | [
"bnpi (homo sapiens)"
] | [
"nprbi (homo sapiens)",
"impnb (homo sapiens)",
"npi (homo sapiens)",
"pnpi (homo sapiens)"
] | Given the context 'Using fluorescent in situ hybridization, we localized hBNPI to the long arm of chromosome 19 (19q13) in close proximity to the late-onset familial Alzheimer's disease locus.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8'? | [
"rab8 (homo sapiens)",
"rab8a, member ras oncogene family (homo sapiens)",
"rab8a (homo sapiens)",
"mel (homo sapiens) (rab8a, member ras oncogene family (homo sapiens))"
] | [
"rab8 (drosophila melanogaster)",
"rabin8 (homo sapiens)",
"rab8a, member ras oncogene family (mus musculus)",
"rab8b, member ras oncogene family (homo sapiens)"
] | Given the context 'In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase.
Rab8 is a small GTP-binding protein that plays a role in vesicular transport from the trans-Golgi network to the basolateral plasma membrane in polarized epithelial cells (MDCK), and to the dendritic surface in hippocampal neurons.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8'? | [
"rab8 (homo sapiens)",
"rab8a, member ras oncogene family (homo sapiens)",
"rab8a (homo sapiens)",
"mel (homo sapiens) (rab8a, member ras oncogene family (homo sapiens))"
] | [
"rab8 (drosophila melanogaster)",
"rabin8 (homo sapiens)",
"rab8a, member ras oncogene family (mus musculus)",
"rab8b, member ras oncogene family (homo sapiens)"
] | Given the context 'In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase.
Rab8 is a small GTP-binding protein that plays a role in vesicular transport from the trans-Golgi network to the basolateral plasma membrane in polarized epithelial cells (MDCK), and to the dendritic surface in hippocampal neurons.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8'? | [
"rab8 (homo sapiens)",
"rab8a, member ras oncogene family (homo sapiens)",
"rab8a (homo sapiens)",
"mel (homo sapiens) (rab8a, member ras oncogene family (homo sapiens))"
] | [
"rab8 (drosophila melanogaster)",
"rabin8 (homo sapiens)",
"rab8a, member ras oncogene family (mus musculus)",
"rab8b, member ras oncogene family (homo sapiens)"
] | Given the context 'As is the case for most other rab proteins, the precise molecular interactions by which rab8 carries out its function remain to be elucidated.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8-interacting protein'? | [
"rab8ip (mus musculus)"
] | [
"rab8ip (homo sapiens)",
"rabin8 (homo sapiens)",
"rab3a interacting protein (homo sapiens)",
"rab8 (homo sapiens)"
] | Given the context 'Here we report the identification and the complete cDNA-derived amino acid sequence of a murine rab8-interacting protein (rab8ip) that specifically interacts with rab8 in a GTP-dependent manner.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8ip'? | [
"rab8ip (mus musculus)"
] | [
"rab8ip (homo sapiens)",
"rabin8 (homo sapiens)",
"rab5ip (homo sapiens)",
"rab3ip (homo sapiens)"
] | Given the context 'Here we report the identification and the complete cDNA-derived amino acid sequence of a murine rab8-interacting protein (rab8ip) that specifically interacts with rab8 in a GTP-dependent manner.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8'? | [
"rab8 (homo sapiens)",
"rab8a, member ras oncogene family (homo sapiens)",
"rab8a (homo sapiens)",
"mel (homo sapiens) (rab8a, member ras oncogene family (homo sapiens))"
] | [
"rab8 (drosophila melanogaster)",
"rabin8 (homo sapiens)",
"rab8a, member ras oncogene family (mus musculus)",
"rab8b, member ras oncogene family (homo sapiens)"
] | Given the context 'Here we report the identification and the complete cDNA-derived amino acid sequence of a murine rab8-interacting protein (rab8ip) that specifically interacts with rab8 in a GTP-dependent manner.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8ip'? | [
"rab8ip (mus musculus)"
] | [
"rab8ip (homo sapiens)",
"rabin8 (homo sapiens)",
"rab5ip (homo sapiens)",
"rab3ip (homo sapiens)"
] | Given the context 'Rab8ip displays 93% identity with the GC kinase, a serine/threonine protein kinase recently identified in human lymphoid tissue that is activated in the stress response.', answer the user's query. |
What is the biomedical concept corresponding to 'gc kinase'? | [
"gck (homo sapiens) (mitogen-activated protein kinase kinase kinase kinase 2 (homo sapiens))"
] | [
"gck (xenopus laevis)",
"gck (xenopus tropicalis)",
"gck-a (xenopus laevis)",
"gck-1 (caenorhabditis elegans)"
] | Given the context 'Rab8ip displays 93% identity with the GC kinase, a serine/threonine protein kinase recently identified in human lymphoid tissue that is activated in the stress response.', answer the user's query. |
What is the biomedical concept corresponding to 'gc kinase'? | [
"gck (homo sapiens) (mitogen-activated protein kinase kinase kinase kinase 2 (homo sapiens))"
] | [
"gck (xenopus laevis)",
"gck (xenopus tropicalis)",
"gck-a (xenopus laevis)",
"gck-1 (caenorhabditis elegans)"
] | Given the context 'Like the GC kinase, rab8ip has protein kinase activity manifested by autophosphorylation and phosphorylation of the classical serine/threonine protein kinase substrates, myelin basic protein and casein.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8ip'? | [
"rab8ip (mus musculus)"
] | [
"rab8ip (homo sapiens)",
"rabin8 (homo sapiens)",
"rab5ip (homo sapiens)",
"rab3ip (homo sapiens)"
] | Given the context 'Like the GC kinase, rab8ip has protein kinase activity manifested by autophosphorylation and phosphorylation of the classical serine/threonine protein kinase substrates, myelin basic protein and casein.', answer the user's query. |
What is the biomedical concept corresponding to 'myelin basic protein'? | [
"myelin basic protein (homo sapiens)",
"mbp (homo sapiens) (myelin basic protein (homo sapiens))"
] | [
"myelin basic protein (mus musculus)",
"myelin basic protein (bos taurus)",
"mbp (mus musculus) (myelin basic protein (mus musculus))",
"myelin-associated oligodendrocytic basic protein (mus musculus)"
] | Given the context 'Like the GC kinase, rab8ip has protein kinase activity manifested by autophosphorylation and phosphorylation of the classical serine/threonine protein kinase substrates, myelin basic protein and casein.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8'? | [
"rab8 (homo sapiens)",
"rab8a, member ras oncogene family (homo sapiens)",
"rab8a (homo sapiens)",
"mel (homo sapiens) (rab8a, member ras oncogene family (homo sapiens))"
] | [
"rab8 (drosophila melanogaster)",
"rabin8 (homo sapiens)",
"rab8a, member ras oncogene family (mus musculus)",
"rab8b, member ras oncogene family (homo sapiens)"
] | Given the context 'When coexpressed in transfected 293T cells, rab8 and the rab8ip/GC kinase formed a complex that could be recovered by immunoprecipitation with antibodies to rab8.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8ip'? | [
"rab8ip (mus musculus)"
] | [
"rab8ip (homo sapiens)",
"rabin8 (homo sapiens)",
"rab5ip (homo sapiens)",
"rab3ip (homo sapiens)"
] | Given the context 'When coexpressed in transfected 293T cells, rab8 and the rab8ip/GC kinase formed a complex that could be recovered by immunoprecipitation with antibodies to rab8.', answer the user's query. |
What is the biomedical concept corresponding to 'gc kinase'? | [
"gck (homo sapiens) (mitogen-activated protein kinase kinase kinase kinase 2 (homo sapiens))"
] | [
"gck (xenopus laevis)",
"gck (xenopus tropicalis)",
"gck-a (xenopus laevis)",
"gck-1 (caenorhabditis elegans)"
] | Given the context 'When coexpressed in transfected 293T cells, rab8 and the rab8ip/GC kinase formed a complex that could be recovered by immunoprecipitation with antibodies to rab8.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8'? | [
"rab8 (homo sapiens)",
"rab8a, member ras oncogene family (homo sapiens)",
"rab8a (homo sapiens)",
"mel (homo sapiens) (rab8a, member ras oncogene family (homo sapiens))"
] | [
"rab8 (drosophila melanogaster)",
"rabin8 (homo sapiens)",
"rab8a, member ras oncogene family (mus musculus)",
"rab8b, member ras oncogene family (homo sapiens)"
] | Given the context 'When coexpressed in transfected 293T cells, rab8 and the rab8ip/GC kinase formed a complex that could be recovered by immunoprecipitation with antibodies to rab8.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8ip'? | [
"rab8ip (mus musculus)"
] | [
"rab8ip (homo sapiens)",
"rabin8 (homo sapiens)",
"rab5ip (homo sapiens)",
"rab3ip (homo sapiens)"
] | Given the context 'Cell fractionation and immunofluorescence analyses indicate that in MDCK cells endogenous rab8ip is present both in the cytosol and as a peripheral membrane protein concentrated in the Golgi region and basolateral plasma membrane domains, sites where rab8 itself is also located.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8'? | [
"rab8 (homo sapiens)",
"rab8a, member ras oncogene family (homo sapiens)",
"rab8a (homo sapiens)",
"mel (homo sapiens) (rab8a, member ras oncogene family (homo sapiens))"
] | [
"rab8 (drosophila melanogaster)",
"rabin8 (homo sapiens)",
"rab8a, member ras oncogene family (mus musculus)",
"rab8b, member ras oncogene family (homo sapiens)"
] | Given the context 'Cell fractionation and immunofluorescence analyses indicate that in MDCK cells endogenous rab8ip is present both in the cytosol and as a peripheral membrane protein concentrated in the Golgi region and basolateral plasma membrane domains, sites where rab8 itself is also located.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8'? | [
"rab8 (homo sapiens)",
"rab8a, member ras oncogene family (homo sapiens)",
"rab8a (homo sapiens)",
"mel (homo sapiens) (rab8a, member ras oncogene family (homo sapiens))"
] | [
"rab8 (drosophila melanogaster)",
"rabin8 (homo sapiens)",
"rab8a, member ras oncogene family (mus musculus)",
"rab8b, member ras oncogene family (homo sapiens)"
] | Given the context 'In light of recent evidence that rab proteins may act by promoting the stabilization of SNARE complexes, the specific GTP-dependent association of rab8 with the rab8ip/GC kinase raises the possibility that rab-regulated protein phosphorylation is important for vesicle targeting or fusion.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8ip'? | [
"rab8ip (mus musculus)"
] | [
"rab8ip (homo sapiens)",
"rabin8 (homo sapiens)",
"rab5ip (homo sapiens)",
"rab3ip (homo sapiens)"
] | Given the context 'In light of recent evidence that rab proteins may act by promoting the stabilization of SNARE complexes, the specific GTP-dependent association of rab8 with the rab8ip/GC kinase raises the possibility that rab-regulated protein phosphorylation is important for vesicle targeting or fusion.', answer the user's query. |
What is the biomedical concept corresponding to 'gc kinase'? | [
"gck (homo sapiens) (mitogen-activated protein kinase kinase kinase kinase 2 (homo sapiens))"
] | [
"gck (xenopus laevis)",
"gck (xenopus tropicalis)",
"gck-a (xenopus laevis)",
"gck-1 (caenorhabditis elegans)"
] | Given the context 'In light of recent evidence that rab proteins may act by promoting the stabilization of SNARE complexes, the specific GTP-dependent association of rab8 with the rab8ip/GC kinase raises the possibility that rab-regulated protein phosphorylation is important for vesicle targeting or fusion.', answer the user's query. |
What is the biomedical concept corresponding to 'rab8ip'? | [
"rab8ip (mus musculus)"
] | [
"rab8ip (homo sapiens)",
"rabin8 (homo sapiens)",
"rab5ip (homo sapiens)",
"rab3ip (homo sapiens)"
] | Given the context 'Moreover, the rab8ip/GC kinase may serve to modulate secretion in response to stress stimuli.', answer the user's query. |
What is the biomedical concept corresponding to 'gc kinase'? | [
"gck (homo sapiens) (mitogen-activated protein kinase kinase kinase kinase 2 (homo sapiens))"
] | [
"gck (xenopus laevis)",
"gck (xenopus tropicalis)",
"gck-a (xenopus laevis)",
"gck-1 (caenorhabditis elegans)"
] | Given the context 'Moreover, the rab8ip/GC kinase may serve to modulate secretion in response to stress stimuli.', answer the user's query. |
What is the biomedical concept corresponding to 'hvmat1'? | [
"vmat1 (homo sapiens)"
] | [
"vmat1 (mus musculus)",
"hvt1 (arabidopsis thaliana)",
"n6amt1 (homo sapiens)",
"solute carrier family 18 (vesicular monoamine), member 1 (mus musculus)"
] | Given the context 'The contribution of the two transporter isoforms to monoamine storage in human neuroendocrine tissues was examined with isoform-specific polyclonal antibodies against hVMAT1 and hVMAT2.', answer the user's query. |
What is the biomedical concept corresponding to 'hvmat2'? | [
"vmat2 (homo sapiens)",
"vat2 (homo sapiens)"
] | [
"avt2 (homo sapiens)",
"solute carrier family 18 (vesicular monoamine), member 2 (mus musculus)",
"vmat2 (mus musculus)",
"n6amt2 (homo sapiens)"
] | Given the context 'The contribution of the two transporter isoforms to monoamine storage in human neuroendocrine tissues was examined with isoform-specific polyclonal antibodies against hVMAT1 and hVMAT2.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat2'? | [
"vmat2 (homo sapiens)",
"vat2 (homo sapiens)"
] | [
"vmat-2 (rattus norvegicus)",
"vmat2 (mus musculus)",
"vmat1 (homo sapiens)",
"slc6a2 (homo sapiens)"
] | Given the context 'Central, peripheral, and enteric neurons express only VMAT2.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat1'? | [
"vmat1 (homo sapiens)",
"vat1 (homo sapiens) (solute carrier family 18 member a1 (homo sapiens))",
"slc18a1 (homo sapiens)"
] | [
"vmat1 (mus musculus)",
"vmat-1 (rattus norvegicus)",
"vmat2 (homo sapiens)",
"solute carrier family 18 (vesicular monoamine), member 1 (mus musculus)"
] | Given the context 'VMAT1 is expressed exclusively in neuroendocrine, including chromaffin and enterochromaffin, cells.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat1'? | [
"vmat1 (homo sapiens)",
"vat1 (homo sapiens) (solute carrier family 18 member a1 (homo sapiens))",
"slc18a1 (homo sapiens)"
] | [
"vmat1 (mus musculus)",
"vmat-1 (rattus norvegicus)",
"vmat2 (homo sapiens)",
"solute carrier family 18 (vesicular monoamine), member 1 (mus musculus)"
] | Given the context 'VMAT1 and VMAT2 are coexpressed in all chromaffin cells of the adrenal medulla.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat2'? | [
"vmat2 (homo sapiens)",
"vat2 (homo sapiens)"
] | [
"vmat-2 (rattus norvegicus)",
"vmat2 (mus musculus)",
"vmat1 (homo sapiens)",
"slc6a2 (homo sapiens)"
] | Given the context 'VMAT1 and VMAT2 are coexpressed in all chromaffin cells of the adrenal medulla.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat2'? | [
"vmat2 (homo sapiens)",
"vat2 (homo sapiens)"
] | [
"vmat-2 (rattus norvegicus)",
"vmat2 (mus musculus)",
"vmat1 (homo sapiens)",
"slc6a2 (homo sapiens)"
] | Given the context 'VMAT2 alone is expressed in histamine-storing enterochromaffin-like cells of the oxyntic mucosa of the stomach.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat2'? | [
"vmat2 (homo sapiens)",
"vat2 (homo sapiens)"
] | [
"vmat-2 (rattus norvegicus)",
"vmat2 (mus musculus)",
"vmat1 (homo sapiens)",
"slc6a2 (homo sapiens)"
] | Given the context 'Catecholamines exhibit a 3-fold higher affinity, and histamine exhibits a 30-fold higher affinity, for VMAT2.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat2'? | [
"vmat2 (homo sapiens)",
"vat2 (homo sapiens)"
] | [
"vmat-2 (rattus norvegicus)",
"vmat2 (mus musculus)",
"vmat1 (homo sapiens)",
"slc6a2 (homo sapiens)"
] | Given the context 'Reserpine and ketanserin are slightly more potent inhibitors of VMAT2-mediated transport than of VMAT1-mediated transport, whereas tetrabenazine binds to and inhibits only VMAT2.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat1'? | [
"vmat1 (homo sapiens)",
"vat1 (homo sapiens) (solute carrier family 18 member a1 (homo sapiens))",
"slc18a1 (homo sapiens)"
] | [
"vmat1 (mus musculus)",
"vmat-1 (rattus norvegicus)",
"vmat2 (homo sapiens)",
"solute carrier family 18 (vesicular monoamine), member 1 (mus musculus)"
] | Given the context 'Reserpine and ketanserin are slightly more potent inhibitors of VMAT2-mediated transport than of VMAT1-mediated transport, whereas tetrabenazine binds to and inhibits only VMAT2.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat2'? | [
"vmat2 (homo sapiens)",
"vat2 (homo sapiens)"
] | [
"vmat-2 (rattus norvegicus)",
"vmat2 (mus musculus)",
"vmat1 (homo sapiens)",
"slc6a2 (homo sapiens)"
] | Given the context 'Reserpine and ketanserin are slightly more potent inhibitors of VMAT2-mediated transport than of VMAT1-mediated transport, whereas tetrabenazine binds to and inhibits only VMAT2.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat2'? | [
"vmat2 (homo sapiens)",
"vat2 (homo sapiens)"
] | [
"vmat-2 (rattus norvegicus)",
"vmat2 (mus musculus)",
"vmat1 (homo sapiens)",
"slc6a2 (homo sapiens)"
] | Given the context 'N-methyl-4-phenylpyridinium, phenylethylamine, amphetamine, and methylenedioxymethamphetamine are all more potent inhibitors of VMAT2 than of VMAT1, whereas fenfluramine is a more potent inhibitor of VMAT1-mediated monamine transport than of VMAT2-mediated monoamine transport.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat1'? | [
"vmat1 (homo sapiens)",
"vat1 (homo sapiens) (solute carrier family 18 member a1 (homo sapiens))",
"slc18a1 (homo sapiens)"
] | [
"vmat1 (mus musculus)",
"vmat-1 (rattus norvegicus)",
"vmat2 (homo sapiens)",
"solute carrier family 18 (vesicular monoamine), member 1 (mus musculus)"
] | Given the context 'N-methyl-4-phenylpyridinium, phenylethylamine, amphetamine, and methylenedioxymethamphetamine are all more potent inhibitors of VMAT2 than of VMAT1, whereas fenfluramine is a more potent inhibitor of VMAT1-mediated monamine transport than of VMAT2-mediated monoamine transport.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat1'? | [
"vmat1 (homo sapiens)",
"vat1 (homo sapiens) (solute carrier family 18 member a1 (homo sapiens))",
"slc18a1 (homo sapiens)"
] | [
"vmat1 (mus musculus)",
"vmat-1 (rattus norvegicus)",
"vmat2 (homo sapiens)",
"solute carrier family 18 (vesicular monoamine), member 1 (mus musculus)"
] | Given the context 'N-methyl-4-phenylpyridinium, phenylethylamine, amphetamine, and methylenedioxymethamphetamine are all more potent inhibitors of VMAT2 than of VMAT1, whereas fenfluramine is a more potent inhibitor of VMAT1-mediated monamine transport than of VMAT2-mediated monoamine transport.', answer the user's query. |
What is the biomedical concept corresponding to 'vmat2'? | [
"vmat2 (homo sapiens)",
"vat2 (homo sapiens)"
] | [
"vmat-2 (rattus norvegicus)",
"vmat2 (mus musculus)",
"vmat1 (homo sapiens)",
"slc6a2 (homo sapiens)"
] | Given the context 'N-methyl-4-phenylpyridinium, phenylethylamine, amphetamine, and methylenedioxymethamphetamine are all more potent inhibitors of VMAT2 than of VMAT1, whereas fenfluramine is a more potent inhibitor of VMAT1-mediated monamine transport than of VMAT2-mediated monoamine transport.', answer the user's query. |
What is the biomedical concept corresponding to 'hvmat1'? | [
"vmat1 (homo sapiens)"
] | [
"vmat1 (mus musculus)",
"hvt1 (arabidopsis thaliana)",
"n6amt1 (homo sapiens)",
"solute carrier family 18 (vesicular monoamine), member 1 (mus musculus)"
] | Given the context 'The unique distributions of hVMAT1 and hVMAT2 provide new markers for multiple neuroendocrine lineages, and examination of their transport properties provides mechanistic insights into the pharmacology and physiology of amine storage in cardiovascular, endocrine, and central nervous system function.', answer the user's query. |
What is the biomedical concept corresponding to 'hvmat2'? | [
"vmat2 (homo sapiens)",
"vat2 (homo sapiens)"
] | [
"avt2 (homo sapiens)",
"solute carrier family 18 (vesicular monoamine), member 2 (mus musculus)",
"vmat2 (mus musculus)",
"n6amt2 (homo sapiens)"
] | Given the context 'The unique distributions of hVMAT1 and hVMAT2 provide new markers for multiple neuroendocrine lineages, and examination of their transport properties provides mechanistic insights into the pharmacology and physiology of amine storage in cardiovascular, endocrine, and central nervous system function.', answer the user's query. |
What is the biomedical concept corresponding to 'c/ebpalpha'? | [
"c/ebp-alpha (homo sapiens)",
"ccaat enhancer binding protein alpha (homo sapiens)",
"cebpa (homo sapiens)"
] | [
"ccaat enhancer binding protein alpha (xenopus tropicalis)",
"c/ebpalpha (xenopus tropicalis)",
"c/ebp-alpha (xenopus tropicalis)",
"c/ebp (xenopus tropicalis)"
] | Given the context 'The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.
', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.
', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'The ob gene product, leptin, apparently exclusively expressed in adipose tissue, is a signaling factor regulating body weight homeostasis and energy balance.', answer the user's query. |
What is the biomedical concept corresponding to 'leptin'? | [
"leptin (homo sapiens)",
"ob (homo sapiens) (leptin (homo sapiens))"
] | [
"leptin, serum levels of (homo sapiens)",
"leptin receptor (homo sapiens)",
"leptin (oryctolagus cuniculus)",
"leptin (rattus norvegicus)"
] | Given the context 'The ob gene product, leptin, apparently exclusively expressed in adipose tissue, is a signaling factor regulating body weight homeostasis and energy balance.', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'ob gene expression is increased in obese rodents and regulated by feeding, insulin, and glucocorticoids, which supports the concept that ob gene expression is under hormonal control, which is expected for a key factor controlling body weight homeostasis and energy balance.', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'ob gene expression is increased in obese rodents and regulated by feeding, insulin, and glucocorticoids, which supports the concept that ob gene expression is under hormonal control, which is expected for a key factor controlling body weight homeostasis and energy balance.', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'In humans, ob mRNA expression is increased in gross obesity; however, the effects of the above factors on human ob expression are unknown.', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'In humans, ob mRNA expression is increased in gross obesity; however, the effects of the above factors on human ob expression are unknown.', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'We describe the structure of the human ob gene and initial functional analysis of its promoter.', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'The human ob gene's three exons cover approximately 15 kb of genomic DNA.', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'Only 217 bp of 5' sequence are required for basal adipose tissue-specific expression of the ob gene as well as enhanced expression by C/EBPalpha.', answer the user's query. |
What is the biomedical concept corresponding to 'c/ebpalpha'? | [
"c/ebp-alpha (homo sapiens)",
"ccaat enhancer binding protein alpha (homo sapiens)",
"cebpa (homo sapiens)"
] | [
"ccaat enhancer binding protein alpha (xenopus tropicalis)",
"c/ebpalpha (xenopus tropicalis)",
"c/ebp-alpha (xenopus tropicalis)",
"c/ebp (xenopus tropicalis)"
] | Given the context 'Only 217 bp of 5' sequence are required for basal adipose tissue-specific expression of the ob gene as well as enhanced expression by C/EBPalpha.', answer the user's query. |
What is the biomedical concept corresponding to 'c/ebpalpha'? | [
"c/ebp-alpha (homo sapiens)",
"ccaat enhancer binding protein alpha (homo sapiens)",
"cebpa (homo sapiens)"
] | [
"ccaat enhancer binding protein alpha (xenopus tropicalis)",
"c/ebpalpha (xenopus tropicalis)",
"c/ebp-alpha (xenopus tropicalis)",
"c/ebp (xenopus tropicalis)"
] | Given the context 'Mutation of the single C/EBPalpha site in this region abolished inducibility of the promoter by C/EBPalpha in cotransfection assays.', answer the user's query. |
What is the biomedical concept corresponding to 'c/ebpalpha'? | [
"c/ebp-alpha (homo sapiens)",
"ccaat enhancer binding protein alpha (homo sapiens)",
"cebpa (homo sapiens)"
] | [
"ccaat enhancer binding protein alpha (xenopus tropicalis)",
"c/ebpalpha (xenopus tropicalis)",
"c/ebp-alpha (xenopus tropicalis)",
"c/ebp (xenopus tropicalis)"
] | Given the context 'Mutation of the single C/EBPalpha site in this region abolished inducibility of the promoter by C/EBPalpha in cotransfection assays.', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'The gene structure will facilitate our analysis of ob mutations in human obesity, whereas knowledge of sequence elements and factors regulating ob gene expression should be of major importance in the prevention and treatment of obesity.', answer the user's query. |
What is the biomedical concept corresponding to 'ob'? | [
"ob (homo sapiens) (leptin (homo sapiens))",
"leptin (homo sapiens)"
] | [
"obr (homo sapiens)",
"obp-1 (homo sapiens)",
"obf (homo sapiens)",
"ob (oryctolagus cuniculus)"
] | Given the context 'The gene structure will facilitate our analysis of ob mutations in human obesity, whereas knowledge of sequence elements and factors regulating ob gene expression should be of major importance in the prevention and treatment of obesity.', answer the user's query. |
What is the biomedical concept corresponding to 'ara70'? | [
"ara70 (homo sapiens)"
] | [
"ara70 (xenopus tropicalis)",
"rpa70 (homo sapiens)",
"ara70 (xenopus laevis) (nuclear receptor coactivator 4 s homeolog (xenopus laevis))",
"ra70 (homo sapiens)"
] | Given the context 'Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.
', answer the user's query. |
What is the biomedical concept corresponding to 'androgen receptor'? | [
"androgen receptor (homo sapiens)",
"ar (homo sapiens) (androgen receptor (homo sapiens))"
] | [
"retinoid x receptor alpha (homo sapiens)",
"c-erba (homo sapiens)",
"thyroid hormone receptor alpha (homo sapiens)",
"c-erba-1 (homo sapiens)"
] | Given the context 'Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.
', answer the user's query. |
What is the biomedical concept corresponding to 'androgen receptor'? | [
"androgen receptor (homo sapiens)",
"ar (homo sapiens) (androgen receptor (homo sapiens))"
] | [
"retinoid x receptor alpha (homo sapiens)",
"c-erba (homo sapiens)",
"thyroid hormone receptor alpha (homo sapiens)",
"c-erba-1 (homo sapiens)"
] | Given the context 'The androgen receptor (AR) is a member of the steroid receptor superfamily that plays an important role in male sexual differentiation and prostate cell proliferation.', answer the user's query. |
What is the biomedical concept corresponding to 'ar'? | [
"ar (homo sapiens) (androgen receptor (homo sapiens))",
"androgen receptor (homo sapiens)"
] | [
"ar1 (homo sapiens)",
"ar (rattus norvegicus) (androgen receptor (rattus norvegicus))",
"ar1 (arabidopsis thaliana)",
"ager1 (homo sapiens)"
] | Given the context 'The androgen receptor (AR) is a member of the steroid receptor superfamily that plays an important role in male sexual differentiation and prostate cell proliferation.', answer the user's query. |
What is the biomedical concept corresponding to 'ar'? | [
"ar (homo sapiens) (androgen receptor (homo sapiens))",
"androgen receptor (homo sapiens)"
] | [
"ar1 (homo sapiens)",
"ar (rattus norvegicus) (androgen receptor (rattus norvegicus))",
"ar1 (arabidopsis thaliana)",
"ager1 (homo sapiens)"
] | Given the context 'Mutations or abnormal expression of AR in prostate cancer can play a key role in the process that changes prostate cancer from androgen-dependent to an androgen-independent stage.', answer the user's query. |
What is the biomedical concept corresponding to 'ara70'? | [
"ara70 (homo sapiens)"
] | [
"ara70 (xenopus tropicalis)",
"rpa70 (homo sapiens)",
"ara70 (xenopus laevis) (nuclear receptor coactivator 4 s homeolog (xenopus laevis))",
"ra70 (homo sapiens)"
] | Given the context 'Using a yeast two-hybrid system, we were able to isolate a ligand-dependent AR-associated protein (ARA70), which functions as an activator to enhance AR transcriptional activity 10-fold in the presence of 10(-10)', answer the user's query. |
What is the biomedical concept corresponding to 'ar'? | [
"ar (homo sapiens) (androgen receptor (homo sapiens))",
"androgen receptor (homo sapiens)"
] | [
"ar1 (homo sapiens)",
"ar (rattus norvegicus) (androgen receptor (rattus norvegicus))",
"ar1 (arabidopsis thaliana)",
"ager1 (homo sapiens)"
] | Given the context 'Using a yeast two-hybrid system, we were able to isolate a ligand-dependent AR-associated protein (ARA70), which functions as an activator to enhance AR transcriptional activity 10-fold in the presence of 10(-10)', answer the user's query. |
What is the biomedical concept corresponding to 'ara70'? | [
"ara70 (homo sapiens)"
] | [
"ara70 (xenopus tropicalis)",
"rpa70 (homo sapiens)",
"ara70 (xenopus laevis) (nuclear receptor coactivator 4 s homeolog (xenopus laevis))",
"ra70 (homo sapiens)"
] | Given the context 'Our data further indicated that ARA70 Will only slightly induce the transcriptional activity of other steroid receptors such as estrogen receptor, glucocorticoid receptor, and progesterone receptor in DU145 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'glucocorticoid receptor'? | [
"gcr (homo sapiens)",
"nr3c1 (homo sapiens)",
"gccr (homo sapiens)",
"gr (homo sapiens)"
] | [
"growth hormone releasing hormone receptor (homo sapiens)",
"growth hormone secretagogue receptor (homo sapiens)",
"growth hormone receptor (homo sapiens)",
"ghr (homo sapiens)"
] | Given the context 'Our data further indicated that ARA70 Will only slightly induce the transcriptional activity of other steroid receptors such as estrogen receptor, glucocorticoid receptor, and progesterone receptor in DU145 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'progesterone receptor'? | [
"progesterone receptor (homo sapiens)",
"pr (homo sapiens) (progesterone receptor (homo sapiens))",
"pgr (homo sapiens)"
] | [
"prolactin receptor (homo sapiens)",
"progesterone receptor (gallus gallus)",
"luteinizing hormone/choriogonadotropin receptor (homo sapiens)",
"progesterone receptor (xenopus tropicalis)"
] | Given the context 'Our data further indicated that ARA70 Will only slightly induce the transcriptional activity of other steroid receptors such as estrogen receptor, glucocorticoid receptor, and progesterone receptor in DU145 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'ar'? | [
"ar (homo sapiens) (androgen receptor (homo sapiens))",
"androgen receptor (homo sapiens)"
] | [
"ar1 (homo sapiens)",
"ar (rattus norvegicus) (androgen receptor (rattus norvegicus))",
"ar1 (arabidopsis thaliana)",
"ager1 (homo sapiens)"
] | Given the context 'Together, these data suggest that AR may need a specific coactivator(s) such as ARA70 for optimal androgen activity.', answer the user's query. |
What is the biomedical concept corresponding to 'ara70'? | [
"ara70 (homo sapiens)"
] | [
"ara70 (xenopus tropicalis)",
"rpa70 (homo sapiens)",
"ara70 (xenopus laevis) (nuclear receptor coactivator 4 s homeolog (xenopus laevis))",
"ra70 (homo sapiens)"
] | Given the context 'Together, these data suggest that AR may need a specific coactivator(s) such as ARA70 for optimal androgen activity.', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family.
', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'The EVI1 gene, located at chromosome band 3q26, is overexpressed in some myeloid leukemia patients with breakpoints either 5' of the gene in the t(3;3)(q21;q26) or 3' of the gene in the inv(3)(q21q26).', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'EVI1 is also expressed as part of a fusion transcript with the transcription factor AML1 in the t(3;21)(q26;q22), associated with myeloid leukemia.', answer the user's query. |
What is the biomedical concept corresponding to 'aml1'? | [
"aml1 (homo sapiens)",
"runx family transcription factor 1 (homo sapiens)"
] | [
"aml3 (homo sapiens)",
"aml2 (homo sapiens)",
"cbf-1 (homo sapiens)",
"cbfa1 (homo sapiens)"
] | Given the context 'EVI1 is also expressed as part of a fusion transcript with the transcription factor AML1 in the t(3;21)(q26;q22), associated with myeloid leukemia.', answer the user's query. |
What is the biomedical concept corresponding to 'aml1'? | [
"aml1 (homo sapiens)",
"runx family transcription factor 1 (homo sapiens)"
] | [
"aml3 (homo sapiens)",
"aml2 (homo sapiens)",
"cbf-1 (homo sapiens)",
"cbfa1 (homo sapiens)"
] | Given the context 'In cells with t(3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1.', answer the user's query. |
What is the biomedical concept corresponding to 'aml1'? | [
"aml1 (homo sapiens)",
"runx family transcription factor 1 (homo sapiens)"
] | [
"aml3 (homo sapiens)",
"aml2 (homo sapiens)",
"cbf-1 (homo sapiens)",
"cbfa1 (homo sapiens)"
] | Given the context 'In cells with t(3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1.', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'In cells with t(3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1.', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped.', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped.', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1 We have analyzed the relationship between MDS1 and EVI1 to determine whether they are two separate genes.', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1 We have analyzed the relationship between MDS1 and EVI1 to determine whether they are two separate genes.', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'In this report, we present evidence indicating that MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame.', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'In this report, we present evidence indicating that MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame.', answer the user's query. |
What is the biomedical concept corresponding to 'retinoblastoma-interacting zinc-finger protein riz'? | [
"riz (homo sapiens)",
"riz1 (homo sapiens)",
"riz2 (homo sapiens)"
] | [
"riaz (homo sapiens)",
"cdkn1a interacting zinc finger protein 1 (homo sapiens)",
"riz (xenopus tropicalis)",
"rb associated krab zinc finger (homo sapiens)"
] | Given the context 'This additional region has about 40% homology at the amino acid level with the PR domain of the retinoblastoma-interacting zinc-finger protein RIZ.', answer the user's query. |
What is the biomedical concept corresponding to 'evi1'? | [
"evi1 (homo sapiens)",
"mds1-evi1 (homo sapiens)"
] | [
"evi-1 (homo sapiens)",
"evin1 (homo sapiens)",
"evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis))",
"evi (homo sapiens)"
] | Given the context 'These results are important in view of the fact that EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.
', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'We have cloned and sequenced the mouse and human homologue of a widely expressed cellular disintegrin, which we have termed MDC9 (for metalloprotease/disintegrin/cysteine-rich protein 9).', answer the user's query. |
What is the biomedical concept corresponding to 'metalloprotease/disintegrin/cysteine-rich protein 9'? | [
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)",
"mdc9 (homo sapiens)"
] | [
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)",
"cpamd9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 9 (xenopus tropicalis)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)"
] | Given the context 'We have cloned and sequenced the mouse and human homologue of a widely expressed cellular disintegrin, which we have termed MDC9 (for metalloprotease/disintegrin/cysteine-rich protein 9).', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'MDC9 contains several distinct protein domains: a signal sequence is followed by a prodomain and a domain with sequence similarity to snake venom metalloproteases, a disintegrin domain, a cysteine-rich region, an EGF repeat, a membrane anchor, and a cytoplasmic tail.', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'The cytoplasmic tail of MDC9 has two proline-rich sequences which can bind the SH3 domain of Src, and may therefore function as SH3 ligand domains.', answer the user's query. |
What is the biomedical concept corresponding to 'src'? | [
"src (homo sapiens)",
"c-src (homo sapiens)",
"src proto-oncogene, non-receptor tyrosine kinase (homo sapiens)",
"p60-src (homo sapiens)"
] | [
"src1 (homo sapiens)",
"c-src (sus scrofa)",
"src-3 (homo sapiens)",
"src3 (homo sapiens)"
] | Given the context 'The cytoplasmic tail of MDC9 has two proline-rich sequences which can bind the SH3 domain of Src, and may therefore function as SH3 ligand domains.', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'Western blot analysis shows that MDC9 is an approximately 84-kD glycoprotein in all mouse tissues examined, and in NIH 3T3 fibroblast and C2C12 myoblast mouse cell lines.', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'MDC9 can be both cell surface biotinylated and 125I-labeled in NIH 3T3 mouse fibroblasts, indicating that the protein is present on the plasma membrane.', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'Expression of MDC9 in COS-7 cells yields an 84-kD protein, and immunofluorescence analysis of COS-7 cells expressing MDC9 shows a staining pattern that is consistent with a plasma membrane localization.', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'Expression of MDC9 in COS-7 cells yields an 84-kD protein, and immunofluorescence analysis of COS-7 cells expressing MDC9 shows a staining pattern that is consistent with a plasma membrane localization.', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'The apparent molecular mass of 84 kD suggests that MDC9 contains a membrane-anchored metalloprotease and disintegrin domain.', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'We propose that MDC9 might function as a membrane-anchored integrin ligand or metalloprotease, or that MDC9 may combine both activities in one protein.', answer the user's query. |
What is the biomedical concept corresponding to 'mdc9'? | [
"mdc9 (homo sapiens)",
"adam metallopeptidase domain 9 (homo sapiens)",
"adam9 (homo sapiens)"
] | [
"mdc9 (mus musculus)",
"mda-9 (homo sapiens)",
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens)"
] | Given the context 'We propose that MDC9 might function as a membrane-anchored integrin ligand or metalloprotease, or that MDC9 may combine both activities in one protein.', answer the user's query. |
What is the biomedical concept corresponding to 'glra1'? | [
"glra1 (homo sapiens)"
] | [
"glra1 (xenopus tropicalis)",
"glra1 (rattus norvegicus)",
"glutamate receptor 1.1-like (glycine max)",
"glra2 (homo sapiens)"
] | Given the context 'A GLRA1 null mutation in recessive hyperekplexia challenges the functional role of glycine receptors.
', answer the user's query. |
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