query string | positive list | negative list | system string |
|---|---|---|---|
What is the biomedical concept corresponding to 'glycine receptor (glyr) alpha 1'? | [
"glycine receptor alpha 1 (homo sapiens)"
] | [
"guanine nucleotide-binding protein alpha-1 subunit (glycine max)",
"glyr-a1 (xenopus laevis) (glycine receptor alpha 1 l homeolog (xenopus laevis))",
"gamma-aminobutyric acid type a receptor subunit alpha1 (homo sapiens)",
"glyr-a1 (xenopus laevis) (glycine receptor alpha 1 s homeolog (xenopus laevis))"
] | Given the context 'Dominant missense mutations in the human glycine receptor (GlyR) alpha 1 subunit gene (GLRA1) give rise to hereditary hyperekplexia.', answer the user's query. |
What is the biomedical concept corresponding to 'glra1'? | [
"glra1 (homo sapiens)"
] | [
"glra1 (xenopus tropicalis)",
"glra1 (rattus norvegicus)",
"glutamate receptor 1.1-like (glycine max)",
"glra2 (homo sapiens)"
] | Given the context 'Dominant missense mutations in the human glycine receptor (GlyR) alpha 1 subunit gene (GLRA1) give rise to hereditary hyperekplexia.', answer the user's query. |
What is the biomedical concept corresponding to 'glra1'? | [
"glra1 (homo sapiens)"
] | [
"glra1 (xenopus tropicalis)",
"glra1 (rattus norvegicus)",
"glutamate receptor 1.1-like (glycine max)",
"glra2 (homo sapiens)"
] | Given the context 'In a recessive case of hyperekplexia, we found a deletion of exons 1-6 of the GLRA1 gene.', answer the user's query. |
What is the biomedical concept corresponding to 'glra1'? | [
"glra1 (homo sapiens)"
] | [
"glra1 (xenopus tropicalis)",
"glra1 (rattus norvegicus)",
"glutamate receptor 1.1-like (glycine max)",
"glra2 (homo sapiens)"
] | Given the context 'Born to consanguineous parents, the affected child is homozygous for this GLRA1(null) allele consistent with a complete loss of gene function.', answer the user's query. |
What is the biomedical concept corresponding to 'glra1'? | [
"glra1 (homo sapiens)"
] | [
"glra1 (xenopus tropicalis)",
"glra1 (rattus norvegicus)",
"glutamate receptor 1.1-like (glycine max)",
"glra2 (homo sapiens)"
] | Given the context 'This case demonstrates that, in contrast to the lethal effect of a null allele in the recessive mouse mutant oscillator (Glra1 spd-ot), the loss of the GlyR alpha 1 subunit is effectively compensated in man.', answer the user's query. |
What is the biomedical concept corresponding to 'glyr alpha 1'? | [
"glycine receptor alpha 1 (homo sapiens)"
] | [
"glyr1 (homo sapiens)",
"glyr-a1 (xenopus laevis) (glycine receptor alpha 1 l homeolog (xenopus laevis))",
"glyr-a1 (xenopus tropicalis)",
"glycine receptor, alpha 1 (rattus norvegicus)"
] | Given the context 'This case demonstrates that, in contrast to the lethal effect of a null allele in the recessive mouse mutant oscillator (Glra1 spd-ot), the loss of the GlyR alpha 1 subunit is effectively compensated in man.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2 ligand'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"fas ligand (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.
', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2 ligand'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"fas ligand (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'We have isolated a new member of this family, designated Apo-2 ligand (Apo-2L), via an expressed sequence tag.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2l'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"apo3l (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'We have isolated a new member of this family, designated Apo-2 ligand (Apo-2L), via an expressed sequence tag.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2l'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"apo3l (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'Apo-2L is a 281-amino acid protein, related most closely to Fas/Apo-1 ligand.', answer the user's query. |
What is the biomedical concept corresponding to 'fas'? | [
"fas cell surface death receptor (homo sapiens)",
"fas (homo sapiens) (fas cell surface death receptor (homo sapiens))"
] | [
"fasas (homo sapiens)",
"fas activated serine/threonine kinase (homo sapiens)",
"fast (homo sapiens) (fas activated serine/threonine kinase (homo sapiens))",
"fasn (homo sapiens)"
] | Given the context 'Apo-2L is a 281-amino acid protein, related most closely to Fas/Apo-1 ligand.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-1 ligand'? | [
"apo-1 (homo sapiens)"
] | [
"apo1 (homo sapiens)",
"fas ligand (homo sapiens)",
"apol1 (homo sapiens)",
"trail (homo sapiens)"
] | Given the context 'Apo-2L is a 281-amino acid protein, related most closely to Fas/Apo-1 ligand.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2l'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"apo3l (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'Transfected Apo-2L is expressed at the cell surface with its C terminus exposed, indicating a type II transmembrane protein topology.', answer the user's query. |
What is the biomedical concept corresponding to 'fas'? | [
"fas cell surface death receptor (homo sapiens)",
"fas (homo sapiens) (fas cell surface death receptor (homo sapiens))"
] | [
"fasas (homo sapiens)",
"fas activated serine/threonine kinase (homo sapiens)",
"fast (homo sapiens) (fas activated serine/threonine kinase (homo sapiens))",
"fasn (homo sapiens)"
] | Given the context 'Like Fas/Apo-1 ligand and TNF, the C-terminal extracellular region of Apo-2L (amino acids 114-281) exhibits a homotrimeric subunit structure.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-1 ligand'? | [
"apo-1 (homo sapiens)"
] | [
"apo1 (homo sapiens)",
"fas ligand (homo sapiens)",
"apol1 (homo sapiens)",
"trail (homo sapiens)"
] | Given the context 'Like Fas/Apo-1 ligand and TNF, the C-terminal extracellular region of Apo-2L (amino acids 114-281) exhibits a homotrimeric subunit structure.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2l'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"apo3l (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'Like Fas/Apo-1 ligand and TNF, the C-terminal extracellular region of Apo-2L (amino acids 114-281) exhibits a homotrimeric subunit structure.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2l'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"apo3l (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'Soluble Apo-2L induces extensive apoptosis in lymphoid as well as non-lymphoid tumor cell lines.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2l'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"apo3l (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'The effect of Apo-2L is not inhibited by soluble Fas/Apo-1 and TNF receptors; moreover, expression of human Fas/Apo-1 in mouse fibroblasts, which confers sensitivity to induction of apoptosis by agonistic anti-Fas/Apo-1 antibody, does not confer sensitivity to Apo-2L. Hence, Apo-2L acts via a receptor which is distinct from Fas/Apo-1 and TNF receptors.', answer the user's query. |
What is the biomedical concept corresponding to 'fas'? | [
"fas cell surface death receptor (homo sapiens)",
"fas (homo sapiens) (fas cell surface death receptor (homo sapiens))"
] | [
"fasas (homo sapiens)",
"fas activated serine/threonine kinase (homo sapiens)",
"fast (homo sapiens) (fas activated serine/threonine kinase (homo sapiens))",
"fasn (homo sapiens)"
] | Given the context 'The effect of Apo-2L is not inhibited by soluble Fas/Apo-1 and TNF receptors; moreover, expression of human Fas/Apo-1 in mouse fibroblasts, which confers sensitivity to induction of apoptosis by agonistic anti-Fas/Apo-1 antibody, does not confer sensitivity to Apo-2L. Hence, Apo-2L acts via a receptor which is distinct from Fas/Apo-1 and TNF receptors.', answer the user's query. |
What is the biomedical concept corresponding to 'fas'? | [
"fas cell surface death receptor (homo sapiens)",
"fas (homo sapiens) (fas cell surface death receptor (homo sapiens))"
] | [
"fasas (homo sapiens)",
"fas activated serine/threonine kinase (homo sapiens)",
"fast (homo sapiens) (fas activated serine/threonine kinase (homo sapiens))",
"fasn (homo sapiens)"
] | Given the context 'The effect of Apo-2L is not inhibited by soluble Fas/Apo-1 and TNF receptors; moreover, expression of human Fas/Apo-1 in mouse fibroblasts, which confers sensitivity to induction of apoptosis by agonistic anti-Fas/Apo-1 antibody, does not confer sensitivity to Apo-2L. Hence, Apo-2L acts via a receptor which is distinct from Fas/Apo-1 and TNF receptors.', answer the user's query. |
What is the biomedical concept corresponding to 'fas'? | [
"fas cell surface death receptor (homo sapiens)",
"fas (homo sapiens) (fas cell surface death receptor (homo sapiens))"
] | [
"fasas (homo sapiens)",
"fas activated serine/threonine kinase (homo sapiens)",
"fast (homo sapiens) (fas activated serine/threonine kinase (homo sapiens))",
"fasn (homo sapiens)"
] | Given the context 'The effect of Apo-2L is not inhibited by soluble Fas/Apo-1 and TNF receptors; moreover, expression of human Fas/Apo-1 in mouse fibroblasts, which confers sensitivity to induction of apoptosis by agonistic anti-Fas/Apo-1 antibody, does not confer sensitivity to Apo-2L. Hence, Apo-2L acts via a receptor which is distinct from Fas/Apo-1 and TNF receptors.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2l'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"apo3l (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'The effect of Apo-2L is not inhibited by soluble Fas/Apo-1 and TNF receptors; moreover, expression of human Fas/Apo-1 in mouse fibroblasts, which confers sensitivity to induction of apoptosis by agonistic anti-Fas/Apo-1 antibody, does not confer sensitivity to Apo-2L. Hence, Apo-2L acts via a receptor which is distinct from Fas/Apo-1 and TNF receptors.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2l'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"apo3l (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'The effect of Apo-2L is not inhibited by soluble Fas/Apo-1 and TNF receptors; moreover, expression of human Fas/Apo-1 in mouse fibroblasts, which confers sensitivity to induction of apoptosis by agonistic anti-Fas/Apo-1 antibody, does not confer sensitivity to Apo-2L. Hence, Apo-2L acts via a receptor which is distinct from Fas/Apo-1 and TNF receptors.', answer the user's query. |
What is the biomedical concept corresponding to 'fas'? | [
"fas cell surface death receptor (homo sapiens)",
"fas (homo sapiens) (fas cell surface death receptor (homo sapiens))"
] | [
"fasas (homo sapiens)",
"fas activated serine/threonine kinase (homo sapiens)",
"fast (homo sapiens) (fas activated serine/threonine kinase (homo sapiens))",
"fasn (homo sapiens)"
] | Given the context 'The effect of Apo-2L is not inhibited by soluble Fas/Apo-1 and TNF receptors; moreover, expression of human Fas/Apo-1 in mouse fibroblasts, which confers sensitivity to induction of apoptosis by agonistic anti-Fas/Apo-1 antibody, does not confer sensitivity to Apo-2L. Hence, Apo-2L acts via a receptor which is distinct from Fas/Apo-1 and TNF receptors.', answer the user's query. |
What is the biomedical concept corresponding to 'fas'? | [
"fas cell surface death receptor (homo sapiens)",
"fas (homo sapiens) (fas cell surface death receptor (homo sapiens))"
] | [
"fasas (homo sapiens)",
"fas activated serine/threonine kinase (homo sapiens)",
"fast (homo sapiens) (fas activated serine/threonine kinase (homo sapiens))",
"fasn (homo sapiens)"
] | Given the context 'These results suggest that, along with other family members such as Fas/Apo-1 ligand and TNF, Apo-2L may serve as an extracellular signal that triggers programmed cell death.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-1 ligand'? | [
"apo-1 (homo sapiens)"
] | [
"apo1 (homo sapiens)",
"fas ligand (homo sapiens)",
"apol1 (homo sapiens)",
"trail (homo sapiens)"
] | Given the context 'These results suggest that, along with other family members such as Fas/Apo-1 ligand and TNF, Apo-2L may serve as an extracellular signal that triggers programmed cell death.', answer the user's query. |
What is the biomedical concept corresponding to 'apo-2l'? | [
"apo-2l (homo sapiens)",
"apo2l (homo sapiens)",
"trail (homo sapiens)"
] | [
"apol2 (homo sapiens)",
"apo2 (homo sapiens)",
"apo3l (homo sapiens)",
"tall-2 (homo sapiens)"
] | Given the context 'These results suggest that, along with other family members such as Fas/Apo-1 ligand and TNF, Apo-2L may serve as an extracellular signal that triggers programmed cell death.', answer the user's query. |
What is the biomedical concept corresponding to 'polypeptide n-acetylgalactosaminyltransferase, galnac-t3'? | [
"polypeptide n-acetylgalactosaminyltransferase 3 (homo sapiens)",
"galnac-t3 (homo sapiens)",
"galnt3 (homo sapiens)"
] | [
"udp-n-acetyl-alpha-d-galactosamine:polypeptide n-acetylgalactosaminyltransferase 3 (galnac-t3) (danio rerio)",
"polypeptide n-acetylgalactosaminyltransferase 3 (xenopus tropicalis)",
"polypeptide n-acetylgalactosaminyltransferase 3 (gallus gallus)",
"polypeptide n-acetylgalactosaminyltransferase 3 (caenorhab... | Given the context 'Polypeptide N-acetylgalactosaminyltransferase, GalNAc-t3.
', answer the user's query. |
What is the biomedical concept corresponding to 'galnac-t3'? | [
"galnac-t3 (homo sapiens)",
"galnt3 (homo sapiens)",
"polypeptide n-acetylgalactosaminyltransferase 3 (homo sapiens)"
] | [
"polypeptide n-acetylgalactosaminyltransferase 3 (xenopus tropicalis)",
"galnt3 (xenopus tropicalis)",
"polypeptide n-acetylgalactosaminyltransferase 3 (gallus gallus)",
"udp-n-acetyl-alpha-d-galactosamine:polypeptide n-acetylgalactosaminyltransferase 3 (galnac-t3) (danio rerio)"
] | Given the context 'Here we report the cDNA cloning and expression of a novel GalNAc-transferase termed GalNAc-T3.', answer the user's query. |
What is the biomedical concept corresponding to 'galnac-t3'? | [
"galnac-t3 (homo sapiens)",
"galnt3 (homo sapiens)",
"polypeptide n-acetylgalactosaminyltransferase 3 (homo sapiens)"
] | [
"polypeptide n-acetylgalactosaminyltransferase 3 (xenopus tropicalis)",
"galnt3 (xenopus tropicalis)",
"polypeptide n-acetylgalactosaminyltransferase 3 (gallus gallus)",
"udp-n-acetyl-alpha-d-galactosamine:polypeptide n-acetylgalactosaminyltransferase 3 (galnac-t3) (danio rerio)"
] | Given the context 'The overall amino acid sequence similarity with GalNAc-T1 and -T2 is approximately 45%; 12 cysteine residues that are shared between GalNAc-T1 and -T2 are also found in GalNAc-T3.', answer the user's query. |
What is the biomedical concept corresponding to 'galnac-t3'? | [
"galnac-t3 (homo sapiens)",
"galnt3 (homo sapiens)",
"polypeptide n-acetylgalactosaminyltransferase 3 (homo sapiens)"
] | [
"polypeptide n-acetylgalactosaminyltransferase 3 (xenopus tropicalis)",
"galnt3 (xenopus tropicalis)",
"polypeptide n-acetylgalactosaminyltransferase 3 (gallus gallus)",
"udp-n-acetyl-alpha-d-galactosamine:polypeptide n-acetylgalactosaminyltransferase 3 (galnac-t3) (danio rerio)"
] | Given the context 'GalNAc-T3 was expressed as a soluble protein without the hydrophobic transmembrane domain in insect cells using a Baculo-virus vector, and the expressed GalNAc-transferase activity showed substrate specificity different from that previously reported for GalNAc-T1 and -T2.', answer the user's query. |
What is the biomedical concept corresponding to 'galnac-t3'? | [
"galnac-t3 (homo sapiens)",
"galnt3 (homo sapiens)",
"polypeptide n-acetylgalactosaminyltransferase 3 (homo sapiens)"
] | [
"polypeptide n-acetylgalactosaminyltransferase 3 (xenopus tropicalis)",
"galnt3 (xenopus tropicalis)",
"polypeptide n-acetylgalactosaminyltransferase 3 (gallus gallus)",
"udp-n-acetyl-alpha-d-galactosamine:polypeptide n-acetylgalactosaminyltransferase 3 (galnac-t3) (danio rerio)"
] | Given the context 'Northern analysis of human organs revealed a very restricted expression pattern of GalNAc-T3.', answer the user's query. |
What is the biomedical concept corresponding to 'mammalian translation initiation factor 5'? | [
"eukaryotic translation initiation factor 5 (homo sapiens)",
"eif-5 (homo sapiens)",
"eif5 (homo sapiens)",
"eif-5a (homo sapiens) (eukaryotic translation initiation factor 5 (homo sapiens))"
] | [
"eukaryotic translation initiation factor 5 (drosophila melanogaster)",
"eif5 (drosophila melanogaster) (eukaryotic translation initiation factor 5 (drosophila melanogaster))",
"eukaryotic translation initiation factor 5 (mus musculus)",
"eukaryotic translation initiation factor 5 (xenopus tropicalis)"
] | Given the context 'Characterization of multiple mRNAs that encode mammalian translation initiation factor 5 (eIF-5).
Eukaryotic translation initiation factor 5 (eIF-5) interacts with the 40 S initiation complex (40S.mRNA.MettRNAf.eIF-2.GTP) to promote the hydrolysis of bound GTP with the concomitant joining of the 60 S ribosomal subunit to the 40 S initiation complex to form a functional 80 S initiation complex.', answer the user's query. |
What is the biomedical concept corresponding to 'eif-5'? | [
"eukaryotic translation initiation factor 5 (homo sapiens)",
"eif-5 (homo sapiens)",
"eif5 (homo sapiens)",
"eif-5a (homo sapiens) (eukaryotic translation initiation factor 5 (homo sapiens))"
] | [
"eif5 (drosophila melanogaster) (eukaryotic translation initiation factor 5 (drosophila melanogaster))",
"eukaryotic translation initiation factor 5 (drosophila melanogaster)",
"translation initiation factor eif5 (saccharomyces cerevisiae s288c)",
"eukaryotic translation initiation factor 5 (xenopus tropicali... | Given the context 'Characterization of multiple mRNAs that encode mammalian translation initiation factor 5 (eIF-5).
Eukaryotic translation initiation factor 5 (eIF-5) interacts with the 40 S initiation complex (40S.mRNA.MettRNAf.eIF-2.GTP) to promote the hydrolysis of bound GTP with the concomitant joining of the 60 S ribosomal subunit to the 40 S initiation complex to form a functional 80 S initiation complex.', answer the user's query. |
What is the biomedical concept corresponding to 'eukaryotic translation initiation factor 5'? | [
"eukaryotic translation initiation factor 5 (homo sapiens)",
"eif-5 (homo sapiens)",
"eif5 (homo sapiens)",
"eif-5a (homo sapiens) (eukaryotic translation initiation factor 5 (homo sapiens))"
] | [
"eif5 (drosophila melanogaster) (eukaryotic translation initiation factor 5 (drosophila melanogaster))",
"eukaryotic translation initiation factor 5 (drosophila melanogaster)",
"eukaryotic translation initiation factor 5 (xenopus tropicalis)",
"eukaryotic translation initiation factor 4e-5 (caenorhabditis ele... | Given the context 'Characterization of multiple mRNAs that encode mammalian translation initiation factor 5 (eIF-5).
Eukaryotic translation initiation factor 5 (eIF-5) interacts with the 40 S initiation complex (40S.mRNA.MettRNAf.eIF-2.GTP) to promote the hydrolysis of bound GTP with the concomitant joining of the 60 S ribosomal subunit to the 40 S initiation complex to form a functional 80 S initiation complex.', answer the user's query. |
What is the biomedical concept corresponding to 'eif-5'? | [
"eukaryotic translation initiation factor 5 (homo sapiens)",
"eif-5 (homo sapiens)",
"eif5 (homo sapiens)",
"eif-5a (homo sapiens) (eukaryotic translation initiation factor 5 (homo sapiens))"
] | [
"eif5 (drosophila melanogaster) (eukaryotic translation initiation factor 5 (drosophila melanogaster))",
"eukaryotic translation initiation factor 5 (drosophila melanogaster)",
"translation initiation factor eif5 (saccharomyces cerevisiae s288c)",
"eukaryotic translation initiation factor 5 (xenopus tropicali... | Given the context 'Characterization of multiple mRNAs that encode mammalian translation initiation factor 5 (eIF-5).
Eukaryotic translation initiation factor 5 (eIF-5) interacts with the 40 S initiation complex (40S.mRNA.MettRNAf.eIF-2.GTP) to promote the hydrolysis of bound GTP with the concomitant joining of the 60 S ribosomal subunit to the 40 S initiation complex to form a functional 80 S initiation complex.', answer the user's query. |
What is the biomedical concept corresponding to 'eif-5'? | [
"eukaryotic translation initiation factor 5 (homo sapiens)",
"eif-5 (homo sapiens)",
"eif5 (homo sapiens)",
"eif-5a (homo sapiens) (eukaryotic translation initiation factor 5 (homo sapiens))"
] | [
"eif5 (drosophila melanogaster) (eukaryotic translation initiation factor 5 (drosophila melanogaster))",
"eukaryotic translation initiation factor 5 (drosophila melanogaster)",
"translation initiation factor eif5 (saccharomyces cerevisiae s288c)",
"eukaryotic translation initiation factor 5 (xenopus tropicali... | Given the context 'In this paper, the multiple mRNAs that encode mammalian eIF-5 have been characterized.', answer the user's query. |
What is the biomedical concept corresponding to 'eif-5'? | [
"eukaryotic translation initiation factor 5 (homo sapiens)",
"eif-5 (homo sapiens)",
"eif5 (homo sapiens)",
"eif-5a (homo sapiens) (eukaryotic translation initiation factor 5 (homo sapiens))"
] | [
"eif5 (drosophila melanogaster) (eukaryotic translation initiation factor 5 (drosophila melanogaster))",
"eukaryotic translation initiation factor 5 (drosophila melanogaster)",
"translation initiation factor eif5 (saccharomyces cerevisiae s288c)",
"eukaryotic translation initiation factor 5 (xenopus tropicali... | Given the context 'In rat tissues, three major eIF-5 mRNAs of 3.5, 2.8, and 2.2 kilobases in length are detected.', answer the user's query. |
What is the biomedical concept corresponding to 'eif-5'? | [
"eukaryotic translation initiation factor 5 (homo sapiens)",
"eif-5 (homo sapiens)",
"eif5 (homo sapiens)",
"eif-5a (homo sapiens) (eukaryotic translation initiation factor 5 (homo sapiens))"
] | [
"eif5 (drosophila melanogaster) (eukaryotic translation initiation factor 5 (drosophila melanogaster))",
"eukaryotic translation initiation factor 5 (drosophila melanogaster)",
"translation initiation factor eif5 (saccharomyces cerevisiae s288c)",
"eukaryotic translation initiation factor 5 (xenopus tropicali... | Given the context 'All major eIF-5 mRNAs are initiated from a single transcription initiation site, contain identical 5'-untranslated and coding regions, but differ from one another only in the length of their 3'-untranslated regions.', answer the user's query. |
What is the biomedical concept corresponding to 'eif-5'? | [
"eukaryotic translation initiation factor 5 (homo sapiens)",
"eif-5 (homo sapiens)",
"eif5 (homo sapiens)",
"eif-5a (homo sapiens) (eukaryotic translation initiation factor 5 (homo sapiens))"
] | [
"eif5 (drosophila melanogaster) (eukaryotic translation initiation factor 5 (drosophila melanogaster))",
"eukaryotic translation initiation factor 5 (drosophila melanogaster)",
"translation initiation factor eif5 (saccharomyces cerevisiae s288c)",
"eukaryotic translation initiation factor 5 (xenopus tropicali... | Given the context 'The different lengths of the 3'-untranslated region of eIF-5 mRNAs are generated by the use of alternative polyadenylation signals.', answer the user's query. |
What is the biomedical concept corresponding to 'eif-5'? | [
"eukaryotic translation initiation factor 5 (homo sapiens)",
"eif-5 (homo sapiens)",
"eif5 (homo sapiens)",
"eif-5a (homo sapiens) (eukaryotic translation initiation factor 5 (homo sapiens))"
] | [
"eif5 (drosophila melanogaster) (eukaryotic translation initiation factor 5 (drosophila melanogaster))",
"eukaryotic translation initiation factor 5 (drosophila melanogaster)",
"translation initiation factor eif5 (saccharomyces cerevisiae s288c)",
"eukaryotic translation initiation factor 5 (xenopus tropicali... | Given the context 'Additionally, we demonstrate tissue-specific variations in eIF-5 mRNA expression as well as preference for polyadenylation sites.', answer the user's query. |
What is the biomedical concept corresponding to 'eif-5'? | [
"eukaryotic translation initiation factor 5 (homo sapiens)",
"eif-5 (homo sapiens)",
"eif5 (homo sapiens)",
"eif-5a (homo sapiens) (eukaryotic translation initiation factor 5 (homo sapiens))"
] | [
"eif5 (drosophila melanogaster) (eukaryotic translation initiation factor 5 (drosophila melanogaster))",
"eukaryotic translation initiation factor 5 (drosophila melanogaster)",
"translation initiation factor eif5 (saccharomyces cerevisiae s288c)",
"eukaryotic translation initiation factor 5 (xenopus tropicali... | Given the context 'These results should lead to increased understanding of the regulation of eIF-5 gene expression.', answer the user's query. |
What is the biomedical concept corresponding to 'ice-lap6'? | [
"ice-lap6 (homo sapiens)"
] | [
"casp6 (homo sapiens)",
"ice-lap6 (xenopus tropicalis)",
"caspase-6 (homo sapiens)",
"ice-lap6 (mus musculus)"
] | Given the context 'ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.
Members of the ICE/Ced-3 gene family are likely effector components of the cell death machinery.', answer the user's query. |
What is the biomedical concept corresponding to 'granzyme b'? | [
"granzyme b (homo sapiens)"
] | [
"granzyme b (mus musculus)",
"granzyme b (bos taurus)",
"granzyme b (rattus norvegicus)",
"granzyme b-like (rattus norvegicus)"
] | Given the context 'ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.
Members of the ICE/Ced-3 gene family are likely effector components of the cell death machinery.', answer the user's query. |
What is the biomedical concept corresponding to 'ice-lap6'? | [
"ice-lap6 (homo sapiens)"
] | [
"casp6 (homo sapiens)",
"ice-lap6 (xenopus tropicalis)",
"caspase-6 (homo sapiens)",
"ice-lap6 (mus musculus)"
] | Given the context 'Here, we characterize a novel member of this family designated ICE-LAP6.', answer the user's query. |
What is the biomedical concept corresponding to 'ice-lap6'? | [
"ice-lap6 (homo sapiens)"
] | [
"casp6 (homo sapiens)",
"ice-lap6 (xenopus tropicalis)",
"caspase-6 (homo sapiens)",
"ice-lap6 (mus musculus)"
] | Given the context 'By phylogenetic analysis, ICE-LAP6 is classified into the Ced-3 subfamily which includes Ced-3, Yama/CPP32/apopain, Mch2, and ICE-LAP3/Mch3/CMH-1.', answer the user's query. |
What is the biomedical concept corresponding to 'cpp32'? | [
"cpp32 (homo sapiens)",
"cpp32b (homo sapiens)"
] | [
"csp32 (drosophila melanogaster) (uncharacterized protein (drosophila melanogaster))",
"hcp32 (homo sapiens)",
"cpp32 (xenopus tropicalis)",
"pp32 (homo sapiens)"
] | Given the context 'By phylogenetic analysis, ICE-LAP6 is classified into the Ced-3 subfamily which includes Ced-3, Yama/CPP32/apopain, Mch2, and ICE-LAP3/Mch3/CMH-1.', answer the user's query. |
What is the biomedical concept corresponding to 'ice-lap3'? | [
"ice-lap3 (homo sapiens)",
"casp-7 (homo sapiens)"
] | [
"ice-lap3 (xenopus tropicalis)",
"casp3 (homo sapiens)",
"ich-3 (homo sapiens)",
"caspase 3 (drosophila melanogaster) (death related ice-like caspase (drosophila melanogaster))"
] | Given the context 'By phylogenetic analysis, ICE-LAP6 is classified into the Ced-3 subfamily which includes Ced-3, Yama/CPP32/apopain, Mch2, and ICE-LAP3/Mch3/CMH-1.', answer the user's query. |
What is the biomedical concept corresponding to 'mch3'? | [
"mch3 (homo sapiens)"
] | [
"mch3 (mus musculus)",
"mch4 (homo sapiens)",
"mch6 (homo sapiens)",
"casp3 (homo sapiens)"
] | Given the context 'By phylogenetic analysis, ICE-LAP6 is classified into the Ced-3 subfamily which includes Ced-3, Yama/CPP32/apopain, Mch2, and ICE-LAP3/Mch3/CMH-1.', answer the user's query. |
What is the biomedical concept corresponding to 'cmh-1'? | [
"cmh-1 (homo sapiens)"
] | [
"cmh-1 (mus musculus)",
"cmh1 (homo sapiens)",
"bhlhc1 (homo sapiens)",
"mch-1r (homo sapiens)"
] | Given the context 'By phylogenetic analysis, ICE-LAP6 is classified into the Ced-3 subfamily which includes Ced-3, Yama/CPP32/apopain, Mch2, and ICE-LAP3/Mch3/CMH-1.', answer the user's query. |
What is the biomedical concept corresponding to 'ice-lap6'? | [
"ice-lap6 (homo sapiens)"
] | [
"casp6 (homo sapiens)",
"ice-lap6 (xenopus tropicalis)",
"caspase-6 (homo sapiens)",
"ice-lap6 (mus musculus)"
] | Given the context 'Interestingly, ICE-LAP6 contains an active site QACGG pentapeptide, rather than the QACRG pentapeptide shared by other family members.', answer the user's query. |
What is the biomedical concept corresponding to 'ice-lap6'? | [
"ice-lap6 (homo sapiens)"
] | [
"casp6 (homo sapiens)",
"ice-lap6 (xenopus tropicalis)",
"caspase-6 (homo sapiens)",
"ice-lap6 (mus musculus)"
] | Given the context 'Overexpression of ICE-LAP6 induces apoptosis in MCF7 breast carcinoma cells.', answer the user's query. |
What is the biomedical concept corresponding to 'ice-lap6'? | [
"ice-lap6 (homo sapiens)"
] | [
"casp6 (homo sapiens)",
"ice-lap6 (xenopus tropicalis)",
"caspase-6 (homo sapiens)",
"ice-lap6 (mus musculus)"
] | Given the context 'More importantly, ICE-LAP6 is proteolytically processed into an active cysteine protease by granzyme B, an important component of cytotoxic T cell-mediated apoptosis.', answer the user's query. |
What is the biomedical concept corresponding to 'granzyme b'? | [
"granzyme b (homo sapiens)"
] | [
"granzyme b (mus musculus)",
"granzyme b (bos taurus)",
"granzyme b (rattus norvegicus)",
"granzyme b-like (rattus norvegicus)"
] | Given the context 'More importantly, ICE-LAP6 is proteolytically processed into an active cysteine protease by granzyme B, an important component of cytotoxic T cell-mediated apoptosis.', answer the user's query. |
What is the biomedical concept corresponding to 'ice-lap6'? | [
"ice-lap6 (homo sapiens)"
] | [
"casp6 (homo sapiens)",
"ice-lap6 (xenopus tropicalis)",
"caspase-6 (homo sapiens)",
"ice-lap6 (mus musculus)"
] | Given the context 'Once activated, ICE-LAP6 is able to cleave the death substrate poly(ADP-ribose) polymerase into signature apoptotic fragments.', answer the user's query. |
What is the biomedical concept corresponding to 'cb2'? | [
"cb2 (homo sapiens)",
"cannabinoid receptor 2 (homo sapiens)"
] | [
"cc-ckr-2 (homo sapiens)",
"gprc2b (homo sapiens)",
"cmkbr2 (homo sapiens)",
"gababr2 (homo sapiens)"
] | Given the context 'The 3.7 kb sequence contains an open reading frame encoding a protein of 347 residues sharing 82% overall identity with the only other known peripheral receptor, human CB2 (hCB2) and shorter than hCB2 by 13 amino acids at the carboxyl terminus.', answer the user's query. |
What is the biomedical concept corresponding to 'cb1'? | [
"cb1r (homo sapiens)",
"cb1 (homo sapiens)",
"cb1a (homo sapiens)",
"cannabinoid receptor 1 (homo sapiens)"
] | [
"cb1 (rattus norvegicus)",
"cb1r (rattus norvegicus)",
"cb1 (mus musculus)",
"cb1r (mus musculus)"
] | Given the context 'Binding experiments with membranes from COS-3 cells transiently expressing mCB2 showed that the synthetic cannabinoid WIN 55212-2 had a 6-fold lower affinity for mCB2 than for hCB2, whereas both receptors showed similar affinities for the agonists CP 55,940, delta(9)-THC and anandamide and almost no affinity for the central receptor- (CB1) specific antagonist SR 141716A.', answer the user's query. |
What is the biomedical concept corresponding to 'cb1'? | [
"cb1r (homo sapiens)",
"cb1 (homo sapiens)",
"cb1a (homo sapiens)",
"cannabinoid receptor 1 (homo sapiens)"
] | [
"cb1 (rattus norvegicus)",
"cb1r (rattus norvegicus)",
"cb1 (mus musculus)",
"cb1r (mus musculus)"
] | Given the context 'SR 141716A failed to antagonize this activity in either cell line, confirming its specificity for CB1.', answer the user's query. |
What is the biomedical concept corresponding to 'glycine receptor beta'? | [
"glycine receptor beta (homo sapiens)",
"glrb (homo sapiens)"
] | [
"glycine receptor beta (bos taurus)",
"glycine receptor, beta (rattus norvegicus)",
"glycine receptor beta (xenopus tropicalis)",
"glycine receptor beta (sus scrofa)"
] | Given the context 'The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes.
', answer the user's query. |
What is the biomedical concept corresponding to 'beta subunit of the human glyr'? | [
"glycine receptor beta (homo sapiens)",
"glrb (homo sapiens)"
] | [
"gababr2 (homo sapiens)",
"gprc2b (homo sapiens)",
"gprg1b (homo sapiens)",
"glyr1 (homo sapiens)"
] | Given the context 'A 2106 bp cDNA, isolated from a human hippocampal cDNA library, contained an open reading frame of 497 amino acids which encodes the beta subunit of the human GlyR. The mature human GlyR beta polypeptide displays 99% amino acid identity with the rat GlyR beta subunit and 48% identity with the human GlyR alpha 1 subunit.', answer the user's query. |
What is the biomedical concept corresponding to 'glyr beta'? | [
"glycine receptor beta (homo sapiens)",
"glrb (homo sapiens)"
] | [
"glycine receptor, beta (rattus norvegicus)",
"gababr2 (homo sapiens)",
"glycine receptor beta (bos taurus)",
"gprc2b (homo sapiens)"
] | Given the context 'A 2106 bp cDNA, isolated from a human hippocampal cDNA library, contained an open reading frame of 497 amino acids which encodes the beta subunit of the human GlyR. The mature human GlyR beta polypeptide displays 99% amino acid identity with the rat GlyR beta subunit and 48% identity with the human GlyR alpha 1 subunit.', answer the user's query. |
What is the biomedical concept corresponding to 'glyr beta'? | [
"glycine receptor, beta (rattus norvegicus)"
] | [
"glycine receptor beta (homo sapiens)",
"glrb (homo sapiens)",
"gababr2 (homo sapiens)",
"glycine receptor beta (bos taurus)"
] | Given the context 'A 2106 bp cDNA, isolated from a human hippocampal cDNA library, contained an open reading frame of 497 amino acids which encodes the beta subunit of the human GlyR. The mature human GlyR beta polypeptide displays 99% amino acid identity with the rat GlyR beta subunit and 48% identity with the human GlyR alpha 1 subunit.', answer the user's query. |
What is the biomedical concept corresponding to 'glyr alpha 1'? | [
"glycine receptor alpha 1 (homo sapiens)"
] | [
"glyr1 (homo sapiens)",
"glyr-a1 (xenopus laevis) (glycine receptor alpha 1 l homeolog (xenopus laevis))",
"glyr-a1 (xenopus tropicalis)",
"glycine receptor, alpha 1 (rattus norvegicus)"
] | Given the context 'A 2106 bp cDNA, isolated from a human hippocampal cDNA library, contained an open reading frame of 497 amino acids which encodes the beta subunit of the human GlyR. The mature human GlyR beta polypeptide displays 99% amino acid identity with the rat GlyR beta subunit and 48% identity with the human GlyR alpha 1 subunit.', answer the user's query. |
What is the biomedical concept corresponding to 'glyr beta'? | [
"glycine receptor beta (homo sapiens)",
"glrb (homo sapiens)"
] | [
"glycine receptor, beta (rattus norvegicus)",
"gababr2 (homo sapiens)",
"glycine receptor beta (bos taurus)",
"gprc2b (homo sapiens)"
] | Given the context 'Neither [3H]strychnine binding nor glycine-gated currents were detected when the human GlyR beta subunit cDNA was expressed in the human embryonic kidney 293 cell line.', answer the user's query. |
What is the biomedical concept corresponding to 'alpha 1 homomeric glyrs'? | [
"glycine receptor alpha 1 (homo sapiens)"
] | [
"alpha1aar (homo sapiens)",
"glyr-a1 (xenopus laevis) (glycine receptor alpha 1 s homeolog (xenopus laevis))",
"guanine nucleotide-binding protein alpha-1 subunit (glycine max)",
"glyr-a1 (xenopus laevis) (glycine receptor alpha 1 l homeolog (xenopus laevis))"
] | Given the context 'However, co-expression of the beta subunit cDNA with the alpha 1 subunit cDNA resulted in expression of functional GlyRs which showed a 4-fold reduction in the EC50 values when compared to alpha 1 homomeric GlyRs.', answer the user's query. |
What is the biomedical concept corresponding to 'alpha 1 glyrs'? | [
"glycine receptor alpha 1 (homo sapiens)"
] | [
"gpr1as (homo sapiens)",
"glyr1 (homo sapiens)",
"glyr-a1 (xenopus laevis) (glycine receptor alpha 1 s homeolog (xenopus laevis))",
"glyr-a1 (xenopus laevis) (glycine receptor alpha 1 l homeolog (xenopus laevis))"
] | Given the context 'Glycine-gated currents of alpha 1/beta GlyRs were 17-fold less sensitive than homomeric alpha 1 GlyRs to the antagonists picrotoxin, picrotoxinin and picrotin, providing clear evidence that heteromeric alpha 1/beta GlyRs were expressed.', answer the user's query. |
What is the biomedical concept corresponding to 'glyr beta'? | [
"glycine receptor beta (homo sapiens)",
"glrb (homo sapiens)"
] | [
"glycine receptor, beta (rattus norvegicus)",
"gababr2 (homo sapiens)",
"glycine receptor beta (bos taurus)",
"gprc2b (homo sapiens)"
] | Given the context 'Fluorescence in situ hybridisation was used to localise the gene encoding the human GlyR beta subunit (GLRB) to chromosome 4q32, a position syntenic with mouse chromosome 3.', answer the user's query. |
What is the biomedical concept corresponding to 'glrb'? | [
"glrb (homo sapiens)"
] | [
"glrb (bos taurus)",
"gl-r (homo sapiens)",
"glrb (rattus norvegicus)",
"glr (homo sapiens)"
] | Given the context 'Fluorescence in situ hybridisation was used to localise the gene encoding the human GlyR beta subunit (GLRB) to chromosome 4q32, a position syntenic with mouse chromosome 3.', answer the user's query. |
What is the biomedical concept corresponding to 'glyr beta'? | [
"glycine receptor beta (homo sapiens)",
"glrb (homo sapiens)"
] | [
"glycine receptor, beta (rattus norvegicus)",
"gababr2 (homo sapiens)",
"glycine receptor beta (bos taurus)",
"gprc2b (homo sapiens)"
] | Given the context 'In situ hybridisation using the human GlyR beta subunit cDNA showed that the murine GlyR beta subunit gene (Glrb) maps to the spastic (spa) locus on mouse chromosome 3 at bands E3-F1.', answer the user's query. |
What is the biomedical concept corresponding to 'glrb'? | [
"glrb (mus musculus)"
] | [
"glrb (homo sapiens)",
"glrb (bos taurus)",
"gl-r (homo sapiens)",
"glrb (rattus norvegicus)"
] | Given the context 'In situ hybridisation using the human GlyR beta subunit cDNA showed that the murine GlyR beta subunit gene (Glrb) maps to the spastic (spa) locus on mouse chromosome 3 at bands E3-F1.', answer the user's query. |
What is the biomedical concept corresponding to 'spastic'? | [
"spastic (mus musculus)"
] | [
"spastic paraplegia 14 (autosomal recessive) (homo sapiens)",
"spasm (homo sapiens)",
"hyperreflexia (homo sapiens)",
"spastic paraplegia 16 (complicated, x-linked recessive) (homo sapiens)"
] | Given the context 'In situ hybridisation using the human GlyR beta subunit cDNA showed that the murine GlyR beta subunit gene (Glrb) maps to the spastic (spa) locus on mouse chromosome 3 at bands E3-F1.', answer the user's query. |
What is the biomedical concept corresponding to 'cdc46'? | [
"cdc46 (homo sapiens)",
"p1-cdc46 (homo sapiens)"
] | [
"cdc46 (saccharomyces cerevisiae s288c)",
"anaphase promoting complex subunit cdc16 (saccharomyces cerevisiae s288c)",
"cdc47 (homo sapiens)",
"cdc16 (saccharomyces cerevisiae s288c)"
] | Given the context 'Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5.
', answer the user's query. |
What is the biomedical concept corresponding to 'hcdc46'? | [
"cdc46 (homo sapiens)"
] | [
"cdc16 (homo sapiens)",
"ccdc46 (homo sapiens)",
"cell division cycle 26 (homo sapiens)",
"cell division cycle protein 16 homolog (caenorhabditis elegans)"
] | Given the context 'Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5.
', answer the user's query. |
What is the biomedical concept corresponding to 'mcm5'? | [
"mcm5 (homo sapiens)",
"minichromosome maintenance complex component 5 (homo sapiens)"
] | [
"mcm dna helicase complex subunit mcm5 (saccharomyces cerevisiae s288c)",
"mcm5 (saccharomyces cerevisiae s288c)",
"minichromosome maintenance 5 (drosophila melanogaster)",
"minichromosome maintenance complex component 5 (mus musculus)"
] | Given the context 'Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5.
', answer the user's query. |
What is the biomedical concept corresponding to 'cdc46'? | [
"cdc46 (saccharomyces cerevisiae s288c)"
] | [
"cdc46 (homo sapiens)",
"p1-cdc46 (homo sapiens)",
"anaphase promoting complex subunit cdc16 (saccharomyces cerevisiae s288c)",
"cdc47 (homo sapiens)"
] | Given the context 'We have isolated the complete cDNA sequence encoding the human homolog of the yeast replication protein Cdc46/Mcm5.', answer the user's query. |
What is the biomedical concept corresponding to 'mcm5'? | [
"mcm dna helicase complex subunit mcm5 (saccharomyces cerevisiae s288c)",
"mcm5 (saccharomyces cerevisiae s288c)"
] | [
"mcm5 (homo sapiens)",
"minichromosome maintenance complex component 5 (homo sapiens)",
"minichromosome maintenance 5 (drosophila melanogaster)",
"minichromosome maintenance complex component 5 (mus musculus)"
] | Given the context 'We have isolated the complete cDNA sequence encoding the human homolog of the yeast replication protein Cdc46/Mcm5.', answer the user's query. |
What is the biomedical concept corresponding to 'cdc46'? | [
"cdc46 (homo sapiens)",
"p1-cdc46 (homo sapiens)"
] | [
"cdc46 (saccharomyces cerevisiae s288c)",
"anaphase promoting complex subunit cdc16 (saccharomyces cerevisiae s288c)",
"cdc47 (homo sapiens)",
"cdc16 (saccharomyces cerevisiae s288c)"
] | Given the context 'The cDNA was used as a probe for chromosomal fluorescence in situ hybridization (FISH), which localized the human Cdc46 gene (CDC46) to chromosome region 22q13.1-->q13.2.', answer the user's query. |
What is the biomedical concept corresponding to 'cdc46'? | [
"cdc46 (homo sapiens)",
"p1-cdc46 (homo sapiens)"
] | [
"cdc46 (saccharomyces cerevisiae s288c)",
"anaphase promoting complex subunit cdc16 (saccharomyces cerevisiae s288c)",
"cdc47 (homo sapiens)",
"cdc16 (saccharomyces cerevisiae s288c)"
] | Given the context 'The cDNA was used as a probe for chromosomal fluorescence in situ hybridization (FISH), which localized the human Cdc46 gene (CDC46) to chromosome region 22q13.1-->q13.2.', answer the user's query. |
What is the biomedical concept corresponding to 'hcdc46'? | [
"cdc46 (homo sapiens)"
] | [
"cdc16 (homo sapiens)",
"ccdc46 (homo sapiens)",
"cell division cycle 26 (homo sapiens)",
"cell division cycle protein 16 homolog (caenorhabditis elegans)"
] | Given the context 'As deduced from the cDNA sequence, human protein hCdc46 is composed of 734 amino acids and contains a central region that is almost 80% identical with the yeast protein.', answer the user's query. |
What is the biomedical concept corresponding to 'hcdc46'? | [
"cdc46 (homo sapiens)"
] | [
"cdc16 (homo sapiens)",
"ccdc46 (homo sapiens)",
"cell division cycle 26 (homo sapiens)",
"cell division cycle protein 16 homolog (caenorhabditis elegans)"
] | Given the context 'Immunoprecipitation experiments with hCdc46-specific antibodies confirm that essentially all nuclear hCdc46 proteins form a stable dimeric complex with protein P1Mcm3.', answer the user's query. |
What is the biomedical concept corresponding to 'hcdc46'? | [
"cdc46 (homo sapiens)"
] | [
"cdc16 (homo sapiens)",
"ccdc46 (homo sapiens)",
"cell division cycle 26 (homo sapiens)",
"cell division cycle protein 16 homolog (caenorhabditis elegans)"
] | Given the context 'Immunoprecipitation experiments with hCdc46-specific antibodies confirm that essentially all nuclear hCdc46 proteins form a stable dimeric complex with protein P1Mcm3.', answer the user's query. |
What is the biomedical concept corresponding to 'p1mcm3'? | [
"p1-mcm3 (homo sapiens)"
] | [
"p1-mcm3 (mus musculus)",
"cnnm3 (mus musculus)",
"p1 (mus musculus) (minichromosome maintenance complex component 3 (mus musculus))",
"minichromosome maintenance complex component 3 (mus musculus)"
] | Given the context 'Immunoprecipitation experiments with hCdc46-specific antibodies confirm that essentially all nuclear hCdc46 proteins form a stable dimeric complex with protein P1Mcm3.', answer the user's query. |
What is the biomedical concept corresponding to 'kor'? | [
"kor (homo sapiens)",
"kor-1 (homo sapiens)",
"kor1 (homo sapiens)",
"oprk (homo sapiens)"
] | [
"kor-3 (rattus norvegicus)",
"kor3 (rattus norvegicus)",
"kor3 (homo sapiens)",
"kor-3 (homo sapiens)"
] | Given the context 'We report herein the presence of kappa opioid receptors (KORs) in human fetal microglia and inhibition of HIV-1 expression in acutely infected microglial cell cultures treated with KOR ligands.', answer the user's query. |
What is the biomedical concept corresponding to 'kor'? | [
"kor (homo sapiens)",
"kor-1 (homo sapiens)",
"kor1 (homo sapiens)",
"oprk (homo sapiens)"
] | [
"kor-3 (rattus norvegicus)",
"kor3 (rattus norvegicus)",
"kor3 (homo sapiens)",
"kor-3 (homo sapiens)"
] | Given the context 'Using reverse transcriptase-polymerase chain reaction and sequencing analyses, we found that mRNA for the KOR was constitutively expressed in microglia and determined that the nucleotide sequence of the open reading frame was identical to that of the human brain KOR gene.', answer the user's query. |
What is the biomedical concept corresponding to 'kor'? | [
"kor (homo sapiens)",
"kor-1 (homo sapiens)",
"kor1 (homo sapiens)",
"oprk (homo sapiens)"
] | [
"kor-3 (rattus norvegicus)",
"kor3 (rattus norvegicus)",
"kor3 (homo sapiens)",
"kor-3 (homo sapiens)"
] | Given the context 'Using reverse transcriptase-polymerase chain reaction and sequencing analyses, we found that mRNA for the KOR was constitutively expressed in microglia and determined that the nucleotide sequence of the open reading frame was identical to that of the human brain KOR gene.', answer the user's query. |
What is the biomedical concept corresponding to 'kor'? | [
"kor (homo sapiens)",
"kor-1 (homo sapiens)",
"kor1 (homo sapiens)",
"oprk (homo sapiens)"
] | [
"kor-3 (rattus norvegicus)",
"kor3 (rattus norvegicus)",
"kor3 (homo sapiens)",
"kor-3 (homo sapiens)"
] | Given the context 'The expression of KOR in microglial cells was confirmed by membrane binding of [3H]U69,593, a kappa-selective ligand, and by indirect immunofluorescence.', answer the user's query. |
What is the biomedical concept corresponding to 'kor'? | [
"kor (homo sapiens)",
"kor-1 (homo sapiens)",
"kor1 (homo sapiens)",
"oprk (homo sapiens)"
] | [
"kor-3 (rattus norvegicus)",
"kor3 (rattus norvegicus)",
"kor3 (homo sapiens)",
"kor-3 (homo sapiens)"
] | Given the context 'This antiviral effect of the kappa ligands was blocked by the specific KOR antagonist, nor-binaltrophimine.', answer the user's query. |
What is the biomedical concept corresponding to 'p97 subunit of the 26s proteasome'? | [
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))"
] | [
"hspc97 (homo sapiens)",
"p97 (homo sapiens) (valosin containing protein (homo sapiens))",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)"
] | Given the context 'cDNA cloning and functional analysis of the p97 subunit of the 26S proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11.
', answer the user's query. |
What is the biomedical concept corresponding to 'type-1 tumor-necrosis-factor-receptor-associated protein-2'? | [
"trap2 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))"
] | [
"receptor accessory protein 2 (homo sapiens)",
"rna polymerase ii associated protein 2 (homo sapiens)",
"rad51 associated protein 2 (homo sapiens)",
"tnf receptor associated factor 2 (homo sapiens)"
] | Given the context 'cDNA cloning and functional analysis of the p97 subunit of the 26S proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11.
', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))"
] | [
"hspc97 (homo sapiens)",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)",
"p97 (drosophila melanogaster) (transitional endoplasmic reticulum 94 (drosophila melanogaster))"
] | Given the context 'Molecular cloning of cDNA for a new regulatory subunit, designated p97, of the human 26S proteasome showed that the polypeptide consists of 908 amino acid residues with a calculated molecular mass of 100184 Da and an isoelectric point of 4.94.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))"
] | [
"hspc97 (homo sapiens)",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)",
"p97 (drosophila melanogaster) (transitional endoplasmic reticulum 94 (drosophila melanogaster))"
] | Given the context 'Computer analysis showed that p97 is very similar to type-1 tumor-necrosis-factor (TNF)-receptor-associated protein (TRAP)-2 and 55.11, both of which were identified recently as binding proteins of the cytoplasmic domain of type-1 TNF receptor by yeast two-hybrid screening.', answer the user's query. |
What is the biomedical concept corresponding to 'type-1 tumor-necrosis-factor (tnf)-receptor-associated protein (trap)-2'? | [
"trap2 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))"
] | [
"trap (homo sapiens) (tnf receptor associated factor 2 (homo sapiens))",
"tra2a (homo sapiens)",
"receptor accessory protein 2 (homo sapiens)",
"thrap2 (homo sapiens)"
] | Given the context 'Computer analysis showed that p97 is very similar to type-1 tumor-necrosis-factor (TNF)-receptor-associated protein (TRAP)-2 and 55.11, both of which were identified recently as binding proteins of the cytoplasmic domain of type-1 TNF receptor by yeast two-hybrid screening.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))"
] | [
"hspc97 (homo sapiens)",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)",
"p97 (drosophila melanogaster) (transitional endoplasmic reticulum 94 (drosophila melanogaster))"
] | Given the context 'Computer-assisted similarity analysis also revealed the high sequence similarity of p97 with a yeast protein whose function is yet unknown, the gene for which is here termed NAS1 (non-ATPase subunit 1).', answer the user's query. |
What is the biomedical concept corresponding to 'nas1'? | [
"nas1 (saccharomyces cerevisiae s288c)"
] | [
"nas1 (homo sapiens) (solute carrier family 13 member 1 (homo sapiens))",
"nas1 (arabidopsis thaliana)",
"nas2 (homo sapiens)",
"nas1 (homo sapiens) (nr2f1 regulatory antisense rna 1 (homo sapiens))"
] | Given the context 'Computer-assisted similarity analysis also revealed the high sequence similarity of p97 with a yeast protein whose function is yet unknown, the gene for which is here termed NAS1 (non-ATPase subunit 1).', answer the user's query. |
What is the biomedical concept corresponding to 'nas1'? | [
"nas1 (saccharomyces cerevisiae s288c)"
] | [
"nas1 (homo sapiens) (solute carrier family 13 member 1 (homo sapiens))",
"nas1 (arabidopsis thaliana)",
"nas2 (homo sapiens)",
"nas1 (homo sapiens) (nr2f1 regulatory antisense rna 1 (homo sapiens))"
] | Given the context 'Disruption of NAS1 resulted in several phenotypes, including lethality and temperature-sensitive growth, depending on the genetic background of the cells used.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))"
] | [
"hspc97 (homo sapiens)",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)",
"p97 (drosophila melanogaster) (transitional endoplasmic reticulum 94 (drosophila melanogaster))"
] | Given the context 'The human p97 cDNA suppressed the growth defect of nas1 disruptant cells, when expressed from single-copy or multi-copy vectors, indicating that p97 is functionally equivalent to yeast Nas1p.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))"
] | [
"hspc97 (homo sapiens)",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)",
"p97 (drosophila melanogaster) (transitional endoplasmic reticulum 94 (drosophila melanogaster))"
] | Given the context 'The human p97 cDNA suppressed the growth defect of nas1 disruptant cells, when expressed from single-copy or multi-copy vectors, indicating that p97 is functionally equivalent to yeast Nas1p.', answer the user's query. |
What is the biomedical concept corresponding to 'nas1p'? | [
"nas1 (saccharomyces cerevisiae s288c)"
] | [
"nas1 (arabidopsis thaliana)",
"nas6p (saccharomyces cerevisiae s288c)",
"nas5 (saccharomyces cerevisiae s288c)",
"nas1 (xenopus laevis) (solute carrier family 13 member 1 s homeolog (xenopus laevis))"
] | Given the context 'The human p97 cDNA suppressed the growth defect of nas1 disruptant cells, when expressed from single-copy or multi-copy vectors, indicating that p97 is functionally equivalent to yeast Nas1p.', answer the user's query. |
What is the biomedical concept corresponding to 'nas1p'? | [
"nas1 (saccharomyces cerevisiae s288c)"
] | [
"nas1 (arabidopsis thaliana)",
"nas6p (saccharomyces cerevisiae s288c)",
"nas5 (saccharomyces cerevisiae s288c)",
"nas1 (xenopus laevis) (solute carrier family 13 member 1 s homeolog (xenopus laevis))"
] | Given the context 'Culturing of the temperature-sensitive nas1 cells at the restrictive temperature promoted the accumulation polyubiquitinated cellular proteins, implying that the 26S proteasome requires a functional Nas1p subunit for ubiquitin-dependent proteolysis.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))"
] | [
"hspc97 (homo sapiens)",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)",
"p97 (drosophila melanogaster) (transitional endoplasmic reticulum 94 (drosophila melanogaster))"
] | Given the context 'These results indicate that p97/Nas1p plays an important regulatory role in the function of the 26S proteasome.', answer the user's query. |
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