query
string
positive
list
negative
list
system
string
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'The polymerase chain reaction was then used to amplify a 550-nucleotide sequence with human liver cDNA as template and primers designed on the basis of the NNMT amino acid sequence.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'The 5'- and 3'-ends of a human liver NNMT cDNA were obtained by use of the rapid amplification of cDNA ends.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'The combined use of these approaches resulted in the isolation of a human liver NNMT cDNA that was 969 nucleotides in length, with a 792-nucleotide open reading frame that encoded a 264-amino acid protein with a calculated molecular mass of 29.6 kDa.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'The human liver NNMT cDNA was transcribed in vitro and translated with a reticulocyte lysate system to yield a protein with a molecular mass of approximately 29 kDa that comigrated during SDS-polyacrylamide gel electrophoresis with photoaffinity-labeled human liver NNMT.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'The human liver NNMT cDNA was transcribed in vitro and translated with a reticulocyte lysate system to yield a protein with a molecular mass of approximately 29 kDa that comigrated during SDS-polyacrylamide gel electrophoresis with photoaffinity-labeled human liver NNMT.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'The NNMT cDNA was also subcloned into the eukaryotic expression vector p91023(B).', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'COS-1 cells transfected with this construct expressed a high level of NNMT enzymatic activity, and the biochemical properties of this activity were similar to those of human liver NNMT.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'COS-1 cells transfected with this construct expressed a high level of NNMT enzymatic activity, and the biochemical properties of this activity were similar to those of human liver NNMT.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'Human liver NNMT and transfected COS-1 cell NNMT had apparent Km values for the two cosubstrates for the reaction, nicotinamide and S-adenosyl-L-methionine, of 0.43 and 0.38 mM and of 1.8 and 2.2 microM, respectively.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'Human liver NNMT and transfected COS-1 cell NNMT had apparent Km values for the two cosubstrates for the reaction, nicotinamide and S-adenosyl-L-methionine, of 0.43 and 0.38 mM and of 1.8 and 2.2 microM, respectively.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'IC50 values for the inhibition of NNMT by N1-methylnicotinamide were 60 and 30 microns for human liver and COS-1 cell-expressed NNMT, respectively.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'IC50 values for the inhibition of NNMT by N1-methylnicotinamide were 60 and 30 microns for human liver and COS-1 cell-expressed NNMT, respectively.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'Cloning of a cDNA for human liver NNMT will help make it possible to test the hypothesis that inheritance may play a role in the regulation of individual differences in human liver NNMT activity.', answer the user's query.
What is the biomedical concept corresponding to 'nnmt'?
[ "nnmt (homo sapiens)", "nicotinamide n-methyltransferase (homo sapiens)" ]
[ "nnmt (mus musculus)", "nnmt (rattus norvegicus)", "nicotinamide n-methyltransferase (mus musculus)", "nnmt (xenopus tropicalis) (provisional ortholog of nicotinamide n-methyltransferase (xenopus tropicalis))" ]
Given the context 'Cloning of a cDNA for human liver NNMT will help make it possible to test the hypothesis that inheritance may play a role in the regulation of individual differences in human liver NNMT activity.', answer the user's query.
What is the biomedical concept corresponding to 'capl'?
[ "capl (homo sapiens)" ]
[ "capl (mus musculus)", "capsl (homo sapiens)", "cmap-like (bos taurus)", "capsl (bos taurus)" ]
Given the context 'Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY. ', answer the user's query.
What is the biomedical concept corresponding to 'cacy'?
[ "cacy (homo sapiens)" ]
[ "casy-1 (caenorhabditis elegans)", "cacy (mus musculus)", "cyy-1 (caenorhabditis elegans)", "pas domain-containing protein cky-1 (caenorhabditis elegans)" ]
Given the context 'Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY. ', answer the user's query.
What is the biomedical concept corresponding to 'capl'?
[ "capl (homo sapiens)" ]
[ "capl (mus musculus)", "capsl (homo sapiens)", "cmap-like (bos taurus)", "capsl (bos taurus)" ]
Given the context 'The S100 proteins CAPL and CACY are expressed in a tissue- and cell-specific manner and have been reported to be associated with the metastatic phenotype of tumor cells.', answer the user's query.
What is the biomedical concept corresponding to 'cacy'?
[ "cacy (homo sapiens)" ]
[ "casy-1 (caenorhabditis elegans)", "cacy (mus musculus)", "cyy-1 (caenorhabditis elegans)", "pas domain-containing protein cky-1 (caenorhabditis elegans)" ]
Given the context 'The S100 proteins CAPL and CACY are expressed in a tissue- and cell-specific manner and have been reported to be associated with the metastatic phenotype of tumor cells.', answer the user's query.
What is the biomedical concept corresponding to 'capl'?
[ "capl (homo sapiens)" ]
[ "capl (mus musculus)", "capsl (homo sapiens)", "cmap-like (bos taurus)", "capsl (bos taurus)" ]
Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', answer the user's query.
What is the biomedical concept corresponding to 'cacy'?
[ "cacy (homo sapiens)" ]
[ "casy-1 (caenorhabditis elegans)", "cacy (mus musculus)", "cyy-1 (caenorhabditis elegans)", "pas domain-containing protein cky-1 (caenorhabditis elegans)" ]
Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', answer the user's query.
What is the biomedical concept corresponding to 'cacy'?
[ "cacy (homo sapiens)" ]
[ "casy-1 (caenorhabditis elegans)", "cacy (mus musculus)", "cyy-1 (caenorhabditis elegans)", "pas domain-containing protein cky-1 (caenorhabditis elegans)" ]
Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', answer the user's query.
What is the biomedical concept corresponding to 'capl'?
[ "capl (homo sapiens)" ]
[ "capl (mus musculus)", "capsl (homo sapiens)", "cmap-like (bos taurus)", "capsl (bos taurus)" ]
Given the context 'The isotherms show slight (CAPL, nH = 1.15) or pronounced (CACY, nH = 1.33) positive cooperativity with K0.5 values of 0.32 mM (CACY) and 0.15 mM (CAPL), indicating that the sites are of the low-affinity type.', answer the user's query.
What is the biomedical concept corresponding to 'cacy'?
[ "cacy (homo sapiens)" ]
[ "casy-1 (caenorhabditis elegans)", "cacy (mus musculus)", "cyy-1 (caenorhabditis elegans)", "pas domain-containing protein cky-1 (caenorhabditis elegans)" ]
Given the context 'Conformational changes in the Tyr microenvironment of CACY indicate that Ca2+ binding induces a shift of Tyr to a less polar environment.', answer the user's query.
What is the biomedical concept corresponding to 'capl'?
[ "capl (homo sapiens)" ]
[ "capl (mus musculus)", "capsl (homo sapiens)", "cmap-like (bos taurus)", "capsl (bos taurus)" ]
Given the context 'The Ca(2+)-induced difference spectra of CAPL are about 3 times smaller than those of CACY, suggesting that the additional Tyr84 in CACY is much more sensitive to Ca2+ than the two Tyr residues conserved in both proteins.', answer the user's query.
What is the biomedical concept corresponding to 'cacy'?
[ "cacy (homo sapiens)" ]
[ "casy-1 (caenorhabditis elegans)", "cacy (mus musculus)", "cyy-1 (caenorhabditis elegans)", "pas domain-containing protein cky-1 (caenorhabditis elegans)" ]
Given the context 'The Ca(2+)-induced difference spectra of CAPL are about 3 times smaller than those of CACY, suggesting that the additional Tyr84 in CACY is much more sensitive to Ca2+ than the two Tyr residues conserved in both proteins.', answer the user's query.
What is the biomedical concept corresponding to 'cacy'?
[ "cacy (homo sapiens)" ]
[ "casy-1 (caenorhabditis elegans)", "cacy (mus musculus)", "cyy-1 (caenorhabditis elegans)", "pas domain-containing protein cky-1 (caenorhabditis elegans)" ]
Given the context 'The Ca(2+)-induced difference spectra of CAPL are about 3 times smaller than those of CACY, suggesting that the additional Tyr84 in CACY is much more sensitive to Ca2+ than the two Tyr residues conserved in both proteins.', answer the user's query.
What is the biomedical concept corresponding to 'x-arrestin'?
[ "arrx (homo sapiens)" ]
[ "arr (drosophila melanogaster) (arrestin 1 (drosophila melanogaster))", "arrestin 3, retinal (x-arrestin) l homeolog (xenopus laevis)", "arrestin (xenopus laevis) (arrestin beta 1 s homeolog (xenopus laevis))", "arrestin 3, retinal (x-arrestin) (xenopus tropicalis)" ]
Given the context 'X-arrestin: a new retinal arrestin mapping to the X chromosome. ', answer the user's query.
What is the biomedical concept corresponding to 'x-arrestin'?
[ "arrx (homo sapiens)" ]
[ "arr (drosophila melanogaster) (arrestin 1 (drosophila melanogaster))", "arrestin 3, retinal (x-arrestin) l homeolog (xenopus laevis)", "arrestin (xenopus laevis) (arrestin beta 1 s homeolog (xenopus laevis))", "arrestin 3, retinal (x-arrestin) (xenopus tropicalis)" ]
Given the context 'Chromosomal mapping localized this new arrestin gene to the proximal long arm of the X chromosome, hence it was named X-arrestin.', answer the user's query.
What is the biomedical concept corresponding to 'g(olf) alpha'?
[ "g protein subunit alpha l (homo sapiens)" ]
[ "g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus)", "galpha(olf) (xenopus tropicalis)" ]
Given the context 'Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system. G(olf) alpha is a G-protein originally believed to mediate signal transduction exclusively within the olfactory neuroepithelium and subsequently found to be a major stimulatory G-protein in the basal ganglia.', answer the user's query.
What is the biomedical concept corresponding to 'g(olf) alpha'?
[ "g protein subunit alpha l (homo sapiens)" ]
[ "g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus)", "galpha(olf) (xenopus tropicalis)" ]
Given the context 'Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system. G(olf) alpha is a G-protein originally believed to mediate signal transduction exclusively within the olfactory neuroepithelium and subsequently found to be a major stimulatory G-protein in the basal ganglia.', answer the user's query.
What is the biomedical concept corresponding to 'g(olf) alpha'?
[ "g protein subunit alpha l (homo sapiens)" ]
[ "g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus)", "galpha(olf) (xenopus tropicalis)" ]
Given the context 'Here we present evidence that G(olf) alpha is expressed in several other tissues.', answer the user's query.
What is the biomedical concept corresponding to 'g(olf) alpha'?
[ "g protein subunit alpha l (homo sapiens)" ]
[ "g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus)", "galpha(olf) (xenopus tropicalis)" ]
Given the context 'The human isoform of G(olf) alpha was isolated from two human insulinoma cDNA libraries.', answer the user's query.
What is the biomedical concept corresponding to 'g(olf) alpha'?
[ "g protein subunit alpha l (homo sapiens)" ]
[ "g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus)", "galpha(olf) (xenopus tropicalis)" ]
Given the context 'Comparison of the human sequence with rat G(olf) alpha shows 91% nucleotide identity (within the coding region) and 99% identity at the amino acid level.', answer the user's query.
What is the biomedical concept corresponding to 'g(olf) alpha'?
[ "g protein subunit alpha l (homo sapiens)" ]
[ "g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus)", "galpha(olf) (xenopus tropicalis)" ]
Given the context 'Northern and reverse transcriptase-polymerase chain reaction analyses indicated that G(olf) alpha is expressed in all human insulinomas examined thus far as well as in normal pancreatic islets.', answer the user's query.
What is the biomedical concept corresponding to 'g(olf) alpha'?
[ "g protein subunit alpha l (homo sapiens)" ]
[ "g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus)", "galpha(olf) (xenopus tropicalis)" ]
Given the context 'G(olf) alpha mRNA was also detected in testis, retina, brain, and liver.', answer the user's query.
What is the biomedical concept corresponding to 'g(olf) alpha'?
[ "g protein subunit alpha l (homo sapiens)" ]
[ "g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus)", "galpha(olf) (xenopus tropicalis)" ]
Given the context 'Western blot analysis of various mouse tissues demonstrated that the level of G(olf) alpha protein in islets is lower than that in the olfactory neuroepithelium and other parts of the brain; its expression in retina, lung, and spleen was moderately higher than that in islets, and its expression in testis approached that in olfactory neuroepithelium.', answer the user's query.
What is the biomedical concept corresponding to 'g(olf) alpha'?
[ "g protein subunit alpha l (homo sapiens)" ]
[ "g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus)", "galpha(olf) (xenopus tropicalis)" ]
Given the context 'G(olf) alpha was also detected by immunohistochemistry in mouse islets, human insulinomas, the epithelial lining of mouse epididymis, photoreceptor cells of mouse retina, and mouse lung alveoli.', answer the user's query.
What is the biomedical concept corresponding to 'g(olf) alpha'?
[ "g protein subunit alpha l (homo sapiens)" ]
[ "g(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "galpha(olf) (xenopus laevis) (g protein subunit alpha l l homeolog (xenopus laevis))", "guanine nucleotide-binding protein g(olf) subunit alpha-like (oryctolagus cuniculus)", "galpha(olf) (xenopus tropicalis)" ]
Given the context 'These findings suggest a role for G(olf) alpha in a diverse population of cells located outside the olfactory neuroepithelium and central nervous system.', answer the user's query.
What is the biomedical concept corresponding to '140-kda subunit of rfc'?
[ "rfc40 (homo sapiens) (replication factor c subunit 1 (homo sapiens))", "replication factor c subunit 1 (homo sapiens)", "rfc1 (homo sapiens) (replication factor c subunit 1 (homo sapiens))" ]
[ "replication factor c subunit 1 (saccharomyces cerevisiae s288c)", "rfc1 (saccharomyces cerevisiae s288c)", "rfc (homo sapiens)", "rfc5 (saccharomyces cerevisiae s288c)" ]
Given the context 'Regions of similarity were also seen between the amino acid sequences of the 140-kDa subunit of RFC, poly(ADP-ribose) polymerase, and bacterial DNA ligases--possibly representing a conserved structural feature of these proteins that bind similar DNA substrates.', answer the user's query.
What is the biomedical concept corresponding to 'caltractin'?
[ "calt (homo sapiens)" ]
[ "caltractin (xenopus tropicalis)", "caltractin (xenopus laevis)", "calbindin 1 (homo sapiens)", "caln1 (homo sapiens)" ]
Given the context 'Molecular cloning and centrosomal localization of human caltractin. Caltractin, a 20-kDa calcium-binding protein, was previously purified and cloned at the DNA level from the unicellular green alga Chlamydomonas.', answer the user's query.
What is the biomedical concept corresponding to 'caltractin'?
[ "calt (homo sapiens)" ]
[ "caltractin (xenopus tropicalis)", "caltractin (xenopus laevis)", "calbindin 1 (homo sapiens)", "caln1 (homo sapiens)" ]
Given the context 'Molecular cloning and centrosomal localization of human caltractin. Caltractin, a 20-kDa calcium-binding protein, was previously purified and cloned at the DNA level from the unicellular green alga Chlamydomonas.', answer the user's query.
What is the biomedical concept corresponding to 'caltractin'?
[ "calt (homo sapiens)" ]
[ "caltractin (xenopus tropicalis)", "caltractin (xenopus laevis)", "calbindin 1 (homo sapiens)", "caln1 (homo sapiens)" ]
Given the context 'Here we report the characterization of a cDNA encoding a human caltractin that shares a high degree of amino acid identity (70%) with its algal counterpart.', answer the user's query.
What is the biomedical concept corresponding to 'caltractin'?
[ "calt (homo sapiens)" ]
[ "caltractin (xenopus tropicalis)", "caltractin (xenopus laevis)", "calbindin 1 (homo sapiens)", "caln1 (homo sapiens)" ]
Given the context 'Caltractin was identified in both HeLa and BHK cells as a 21-kDa polypeptide specifically localized to the centrosome of interphase and mitotic cells.', answer the user's query.
What is the biomedical concept corresponding to 'caltractin'?
[ "calt (homo sapiens)" ]
[ "caltractin (xenopus tropicalis)", "caltractin (xenopus laevis)", "calbindin 1 (homo sapiens)", "caln1 (homo sapiens)" ]
Given the context 'The high level of conservation in the amino acid sequence of caltractin from algae to humans and its association with the major microtubule-organizing center in the cell suggest that caltractin plays a fundamental role in microtubule-organizing center structure and function.', answer the user's query.
What is the biomedical concept corresponding to 'caltractin'?
[ "calt (homo sapiens)" ]
[ "caltractin (xenopus tropicalis)", "caltractin (xenopus laevis)", "calbindin 1 (homo sapiens)", "caln1 (homo sapiens)" ]
Given the context 'The high level of conservation in the amino acid sequence of caltractin from algae to humans and its association with the major microtubule-organizing center in the cell suggest that caltractin plays a fundamental role in microtubule-organizing center structure and function.', answer the user's query.
What is the biomedical concept corresponding to 'efp'?
[ "efp (homo sapiens)" ]
[ "efp1 (homo sapiens)", "efp (escherichia coli str. k-12 substr. mg1655)", "epf (homo sapiens)", "efe (homo sapiens)" ]
Given the context 'It has a RING finger motif present in a family of apparent DNA-binding proteins and is designated estrogen-responsive finger protein (efp).', answer the user's query.
What is the biomedical concept corresponding to 'efp'?
[ "efp (homo sapiens)" ]
[ "efp1 (homo sapiens)", "efp (escherichia coli str. k-12 substr. mg1655)", "epf (homo sapiens)", "efe (homo sapiens)" ]
Given the context 'efp cDNA contains a consensus estrogen-responsive element at the 3' untranslated region that can act as a downstream estrogen-dependent enhancer.', answer the user's query.
What is the biomedical concept corresponding to 'efp'?
[ "efp (homo sapiens)" ]
[ "efp1 (homo sapiens)", "efp (escherichia coli str. k-12 substr. mg1655)", "epf (homo sapiens)", "efe (homo sapiens)" ]
Given the context 'Moreover, efp is regulated by estrogen as demonstrated at both the mRNA and the protein level in ER-positive cells derived from mammary gland.', answer the user's query.
What is the biomedical concept corresponding to 'efp'?
[ "efp (homo sapiens)" ]
[ "efp1 (homo sapiens)", "efp (escherichia coli str. k-12 substr. mg1655)", "epf (homo sapiens)", "efe (homo sapiens)" ]
Given the context 'These data suggest that efp may represent an estrogen-responsive transcription factor that mediates phenotypic expression of the diverse estrogen action.', answer the user's query.
What is the biomedical concept corresponding to 'lon protease'?
[ "lon protease (escherichia coli str. k-12 substr. mg1655)", "lon (escherichia coli str. k-12 substr. mg1655)" ]
[ "lon (drosophila melanogaster) (lon protease (drosophila melanogaster))", "lon protease homolog, mitochondrial (caenorhabditis elegans)", "lon (homo sapiens)", "lon protease (drosophila melanogaster)" ]
Given the context 'A human mitochondrial ATP-dependent protease that is highly homologous to bacterial Lon protease. ', answer the user's query.
What is the biomedical concept corresponding to 'lon protease'?
[ "lon (homo sapiens)", "lonp1 (homo sapiens)", "lon peptidase 1, mitochondrial (homo sapiens)" ]
[ "lon (drosophila melanogaster) (lon protease (drosophila melanogaster))", "lon protease homolog, mitochondrial (caenorhabditis elegans)", "lon protease (escherichia coli str. k-12 substr. mg1655)", "lon protease (drosophila melanogaster)" ]
Given the context 'A single species of mRNA was found for this Lon protease in all human tissues examined.', answer the user's query.
What is the biomedical concept corresponding to 'lon protease'?
[ "lon (homo sapiens)", "lonp1 (homo sapiens)", "lon peptidase 1, mitochondrial (homo sapiens)" ]
[ "lon (drosophila melanogaster) (lon protease (drosophila melanogaster))", "lon protease homolog, mitochondrial (caenorhabditis elegans)", "lon protease (escherichia coli str. k-12 substr. mg1655)", "lon protease (drosophila melanogaster)" ]
Given the context 'Immunofluorescence microscopy suggested a predominantly mitochondrial localization for the Lon protease in cultured human cells.', answer the user's query.
What is the biomedical concept corresponding to 'lon'?
[ "lon protease (escherichia coli str. k-12 substr. mg1655)", "lon (escherichia coli str. k-12 substr. mg1655)" ]
[ "lon protease homolog, mitochondrial (caenorhabditis elegans)", "lon (drosophila melanogaster) (lon protease (drosophila melanogaster))", "lon (homo sapiens)", "lonp1 (homo sapiens)" ]
Given the context 'A truncated LON gene, in which translation was initiated at Met118 of the coding sequence, was expressed in Escherichia coli and produced a protease that degraded alpha-casein in vitro in an ATP-dependent manner and had other properties similar to E. coli Lon protease.', answer the user's query.
What is the biomedical concept corresponding to 'lon protease'?
[ "lon protease (escherichia coli str. k-12 substr. mg1655)", "lon (escherichia coli str. k-12 substr. mg1655)" ]
[ "lon (drosophila melanogaster) (lon protease (drosophila melanogaster))", "lon protease homolog, mitochondrial (caenorhabditis elegans)", "lon (homo sapiens)", "lon protease (drosophila melanogaster)" ]
Given the context 'A truncated LON gene, in which translation was initiated at Met118 of the coding sequence, was expressed in Escherichia coli and produced a protease that degraded alpha-casein in vitro in an ATP-dependent manner and had other properties similar to E. coli Lon protease.', answer the user's query.
What is the biomedical concept corresponding to 'nac'?
[ "nacp (homo sapiens)" ]
[ "naca (homo sapiens)", "beta-naca (homo sapiens)", "nac (escherichia coli str. k-12 substr. mg1655)", "nac (drosophila melanogaster) (neuronally altered carbohydrate (drosophila melanogaster))" ]
Given the context 'We tentatively named this 35-amino acid peptide NAC (non-A beta component of AD amyloid) and its precursor NACP.', answer the user's query.
What is the biomedical concept corresponding to 'non-a beta component of ad amyloid'?
[ "synuclein alpha (homo sapiens)", "snca (homo sapiens)" ]
[ "synuclein beta (homo sapiens)", "abeta (homo sapiens)", "synuclein alpha (rattus norvegicus)", "adn (homo sapiens)" ]
Given the context 'We tentatively named this 35-amino acid peptide NAC (non-A beta component of AD amyloid) and its precursor NACP.', answer the user's query.
What is the biomedical concept corresponding to 'nacp'?
[ "nacp (homo sapiens)" ]
[ "naca (homo sapiens)", "nacap1 (homo sapiens)", "nac1a (homo sapiens)", "nac domain protein nac1 (glycine max)" ]
Given the context 'We tentatively named this 35-amino acid peptide NAC (non-A beta component of AD amyloid) and its precursor NACP.', answer the user's query.
What is the biomedical concept corresponding to 'nac'?
[ "nacp (homo sapiens)" ]
[ "naca (homo sapiens)", "beta-naca (homo sapiens)", "nac (escherichia coli str. k-12 substr. mg1655)", "nac (drosophila melanogaster) (neuronally altered carbohydrate (drosophila melanogaster))" ]
Given the context 'NAC is the second component, after A beta, identified chemically in the purified AD amyloid preparation.', answer the user's query.
What is the biomedical concept corresponding to 'nac'?
[ "nacp (homo sapiens)" ]
[ "naca (homo sapiens)", "beta-naca (homo sapiens)", "nac (escherichia coli str. k-12 substr. mg1655)", "nac (drosophila melanogaster) (neuronally altered carbohydrate (drosophila melanogaster))" ]
Given the context 'Secondary structure predictions indicate that the NAC peptide sequence has a strong tendency to form beta-structures consistent with its association with amyloid.', answer the user's query.
What is the biomedical concept corresponding to 'nacp'?
[ "nacp (homo sapiens)" ]
[ "naca (homo sapiens)", "nacap1 (homo sapiens)", "nac1a (homo sapiens)", "nac domain protein nac1 (glycine max)" ]
Given the context 'NACP is detected as a M(r) 19,000 protein in the cytosolic fraction of brain homogenates and comigrates on immunoblots with NACP synthesized in Escherichia coli from NACP cDNA.', answer the user's query.
What is the biomedical concept corresponding to 'nacp'?
[ "nacp (homo sapiens)" ]
[ "naca (homo sapiens)", "nacap1 (homo sapiens)", "nac1a (homo sapiens)", "nac domain protein nac1 (glycine max)" ]
Given the context 'NACP is detected as a M(r) 19,000 protein in the cytosolic fraction of brain homogenates and comigrates on immunoblots with NACP synthesized in Escherichia coli from NACP cDNA.', answer the user's query.
What is the biomedical concept corresponding to 'nacp'?
[ "nacp (homo sapiens)" ]
[ "naca (homo sapiens)", "nacap1 (homo sapiens)", "nac1a (homo sapiens)", "nac domain protein nac1 (glycine max)" ]
Given the context 'NACP is detected as a M(r) 19,000 protein in the cytosolic fraction of brain homogenates and comigrates on immunoblots with NACP synthesized in Escherichia coli from NACP cDNA.', answer the user's query.
What is the biomedical concept corresponding to 'nacp'?
[ "nacp (homo sapiens)" ]
[ "naca (homo sapiens)", "nacap1 (homo sapiens)", "nac1a (homo sapiens)", "nac domain protein nac1 (glycine max)" ]
Given the context 'NACP mRNA is expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver, suggesting its ubiquitous and brain-specific functions.', answer the user's query.
What is the biomedical concept corresponding to 'nacp'?
[ "nacp (homo sapiens)" ]
[ "naca (homo sapiens)", "nacap1 (homo sapiens)", "nac1a (homo sapiens)", "nac domain protein nac1 (glycine max)" ]
Given the context 'The availability of the cDNA encoding full-length NACP should help to elucidate the mechanisms of amyloidosis in AD.', answer the user's query.
What is the biomedical concept corresponding to 'nrf1'?
[ "nrf-1 (homo sapiens)", "nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))" ]
[ "nrf (homo sapiens)", "nuclear respiratory factor 1 (homo sapiens)", "nrf1 (homo sapiens) (nuclear respiratory factor 1 (homo sapiens))", "nrbf1 (homo sapiens)" ]
Given the context 'Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast. ', answer the user's query.
What is the biomedical concept corresponding to 'nrf1'?
[ "nrf-1 (homo sapiens)", "nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))" ]
[ "nrf (homo sapiens)", "nuclear respiratory factor 1 (homo sapiens)", "nrf1 (homo sapiens) (nuclear respiratory factor 1 (homo sapiens))", "nrbf1 (homo sapiens)" ]
Given the context 'We have devised a complementation assay in yeast to clone mammalian transcriptional activators and have used it to identify a human basic leucine-zipper transcription factor that we have designated Nrf1 for NF-E2-related factor 1.', answer the user's query.
What is the biomedical concept corresponding to 'nf-e2-related factor 1'?
[ "nfe2 like bzip transcription factor 1 (homo sapiens)", "nfe2l1 (homo sapiens)", "nrf-1 (homo sapiens)" ]
[ "nfe2 like bzip transcription factor 1 (rattus norvegicus)", "nfe2l1_retired (rattus norvegicus)", "nfe2 like bzip transcription factor 1 (xenopus tropicalis)", "nfe2l1 (rattus norvegicus)" ]
Given the context 'We have devised a complementation assay in yeast to clone mammalian transcriptional activators and have used it to identify a human basic leucine-zipper transcription factor that we have designated Nrf1 for NF-E2-related factor 1.', answer the user's query.
What is the biomedical concept corresponding to 'nrf1'?
[ "nrf-1 (homo sapiens)", "nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))" ]
[ "nrf (homo sapiens)", "nuclear respiratory factor 1 (homo sapiens)", "nrf1 (homo sapiens) (nuclear respiratory factor 1 (homo sapiens))", "nrbf1 (homo sapiens)" ]
Given the context 'Nrf1 potentially encodes a 742-aa protein and displays marked homology to the mouse and human NF-E2 transcription factors.', answer the user's query.
What is the biomedical concept corresponding to 'nrf1'?
[ "nrf-1 (homo sapiens)", "nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))" ]
[ "nrf (homo sapiens)", "nuclear respiratory factor 1 (homo sapiens)", "nrf1 (homo sapiens) (nuclear respiratory factor 1 (homo sapiens))", "nrbf1 (homo sapiens)" ]
Given the context 'Nrf1 activates transcription via NF-E2 binding sites in yeast cells.', answer the user's query.
What is the biomedical concept corresponding to 'nrf1'?
[ "nrf-1 (homo sapiens)", "nrf1 (homo sapiens) (nfe2 like bzip transcription factor 1 (homo sapiens))" ]
[ "nrf (homo sapiens)", "nuclear respiratory factor 1 (homo sapiens)", "nrf1 (homo sapiens) (nuclear respiratory factor 1 (homo sapiens))", "nrbf1 (homo sapiens)" ]
Given the context 'The ubiquitous expression pattern of Nrf1 and the range of promoters containing the NF-E2 binding motif suggest that this gene may play a role in the regulation of heme synthesis and ferritin genes.', answer the user's query.
What is the biomedical concept corresponding to 'beta-subunit of rod phosphodiesterase'?
[ "pdeb (homo sapiens)", "gmp-pdebeta (homo sapiens)", "pde6b (homo sapiens)" ]
[ "phosphodiesterase 1b (homo sapiens)", "pde1b (homo sapiens)", "pdeivb (homo sapiens)", "phosphodiesterase 6b, cgmp-specific, rod, beta (danio rerio)" ]
Given the context 'Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa. ', answer the user's query.
What is the biomedical concept corresponding to 'beta-subunit of rod cgmp phosphodiesterase'?
[ "gmp-pdebeta (homo sapiens)", "pdeb (homo sapiens)", "pde6b (homo sapiens)" ]
[ "pde1b (homo sapiens)", "phosphodiesterase 1b (homo sapiens)", "pde3b (homo sapiens)", "pdeivb (homo sapiens)" ]
Given the context 'We have found four mutations in the human gene encoding the beta-subunit of rod cGMP phosphodiesterase (PDE beta) that cosegregate with autosomal recessive retinitis pigmentosa, a degenerative disease of photoreceptors.', answer the user's query.
What is the biomedical concept corresponding to 'pde beta'?
[ "pdeb (homo sapiens)", "gmp-pdebeta (homo sapiens)", "pde6b (homo sapiens)" ]
[ "pde1b (homo sapiens)", "pde3b (homo sapiens)", "phosphodiesterase 1b (homo sapiens)", "pdeivb (homo sapiens)" ]
Given the context 'We have found four mutations in the human gene encoding the beta-subunit of rod cGMP phosphodiesterase (PDE beta) that cosegregate with autosomal recessive retinitis pigmentosa, a degenerative disease of photoreceptors.', answer the user's query.
What is the biomedical concept corresponding to 'pde beta'?
[ "pdeb (homo sapiens)", "gmp-pdebeta (homo sapiens)", "pde6b (homo sapiens)" ]
[ "pde1b (homo sapiens)", "pde3b (homo sapiens)", "phosphodiesterase 1b (homo sapiens)", "pdeivb (homo sapiens)" ]
Given the context 'PDE beta is the second member of the phototransduction cascade besides rhodopsin that is absent or altered as a cause of retinitis pigmentosa, suggesting that other members of this pathway may be defective in other forms of this disease.', answer the user's query.
What is the biomedical concept corresponding to 'rhodopsin'?
[ "rhodopsin (homo sapiens)", "rho (homo sapiens) (rhodopsin (homo sapiens))" ]
[ "retinal pigment epithelium-derived rhodopsin homolog (xenopus tropicalis)", "retinal pigment epithelium-derived rhodopsin homolog (homo sapiens)", "rh (drosophila melanogaster) (rhodopsin 3 (drosophila melanogaster))", "retinal pigment epithelium-derived rhodopsin homolog (bos taurus)" ]
Given the context 'PDE beta is the second member of the phototransduction cascade besides rhodopsin that is absent or altered as a cause of retinitis pigmentosa, suggesting that other members of this pathway may be defective in other forms of this disease.', answer the user's query.
What is the biomedical concept corresponding to 'c-rel'?
[ "c-rel (homo sapiens)", "rel proto-oncogene, nf-kb subunit (homo sapiens)", "rel (homo sapiens)" ]
[ "rel-b (homo sapiens)", "relb proto-oncogene, nf-kb subunit (homo sapiens)", "v-rel avian reticuloendotheliosis viral oncogene homolog (xenopus tropicalis)", "i-rel (homo sapiens)" ]
Given the context 'Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization. ', answer the user's query.
What is the biomedical concept corresponding to 'nf-kappa bp50'?
[ "nfkb-p50 (homo sapiens)", "nf-kappa-b1 (homo sapiens)", "nf-kb (homo sapiens)", "nfkb-p105 (homo sapiens)", "nuclear factor kappa b subunit 1 (homo sapiens)" ]
[ "rela proto-oncogene, nf-kb subunit (homo sapiens)", "rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens)", "nuclear factor kappa b subunit 2 (homo sapiens)", "relb proto-oncogene, nf-kb subunit (homo sapiens)" ]
Given the context 'Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization. ', answer the user's query.
What is the biomedical concept corresponding to 'nf-kappa bp65'?
[ "rela proto-oncogene, nf-kb subunit (homo sapiens)", "p65 (homo sapiens) (rela proto-oncogene, nf-kb subunit (homo sapiens))" ]
[ "nuclear factor kappa b subunit 2 (homo sapiens)", "nf-kb (homo sapiens)", "nf-kb2 (homo sapiens)", "nf-kappab (homo sapiens)" ]
Given the context 'Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization. ', answer the user's query.
What is the biomedical concept corresponding to 'lyt-10'?
[ "lyt-10 (homo sapiens)", "lyt10 (homo sapiens)" ]
[ "interleukin 10 (homo sapiens)", "lyt-10 (xenopus tropicalis)", "ip-10 (homo sapiens)", "interleukin 1 family member 10 (homo sapiens)" ]
Given the context 'Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization. ', answer the user's query.
What is the biomedical concept corresponding to 'c-rel'?
[ "c-rel (homo sapiens)", "rel proto-oncogene, nf-kb subunit (homo sapiens)", "rel (homo sapiens)" ]
[ "rel-b (homo sapiens)", "relb proto-oncogene, nf-kb subunit (homo sapiens)", "v-rel avian reticuloendotheliosis viral oncogene homolog (xenopus tropicalis)", "i-rel (homo sapiens)" ]
Given the context 'We have used fluorescence in situ hybridization (FISH) to perform precise chromosomal mapping of the genes encoding the transcription factors c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10.', answer the user's query.
What is the biomedical concept corresponding to 'nf-kappa bp50'?
[ "nfkb-p50 (homo sapiens)", "nf-kappa-b1 (homo sapiens)", "nf-kb (homo sapiens)", "nfkb-p105 (homo sapiens)", "nuclear factor kappa b subunit 1 (homo sapiens)" ]
[ "rela proto-oncogene, nf-kb subunit (homo sapiens)", "rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens)", "nuclear factor kappa b subunit 2 (homo sapiens)", "relb proto-oncogene, nf-kb subunit (homo sapiens)" ]
Given the context 'We have used fluorescence in situ hybridization (FISH) to perform precise chromosomal mapping of the genes encoding the transcription factors c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10.', answer the user's query.
What is the biomedical concept corresponding to 'nf-kappa bp65'?
[ "rela proto-oncogene, nf-kb subunit (homo sapiens)", "p65 (homo sapiens) (rela proto-oncogene, nf-kb subunit (homo sapiens))" ]
[ "nuclear factor kappa b subunit 2 (homo sapiens)", "nf-kb (homo sapiens)", "nf-kb2 (homo sapiens)", "nf-kappab (homo sapiens)" ]
Given the context 'We have used fluorescence in situ hybridization (FISH) to perform precise chromosomal mapping of the genes encoding the transcription factors c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10.', answer the user's query.
What is the biomedical concept corresponding to 'lyt-10'?
[ "lyt-10 (homo sapiens)", "lyt10 (homo sapiens)" ]
[ "interleukin 10 (homo sapiens)", "lyt-10 (xenopus tropicalis)", "ip-10 (homo sapiens)", "interleukin 1 family member 10 (homo sapiens)" ]
Given the context 'We have used fluorescence in situ hybridization (FISH) to perform precise chromosomal mapping of the genes encoding the transcription factors c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10.', answer the user's query.
What is the biomedical concept corresponding to 'c-rel'?
[ "c-rel (homo sapiens)", "rel proto-oncogene, nf-kb subunit (homo sapiens)", "rel (homo sapiens)" ]
[ "rel-b (homo sapiens)", "relb proto-oncogene, nf-kb subunit (homo sapiens)", "v-rel avian reticuloendotheliosis viral oncogene homolog (xenopus tropicalis)", "i-rel (homo sapiens)" ]
Given the context 'The previously published assignments of c-rel and NF-kappa Bp50 have been refined to specific bands.', answer the user's query.
What is the biomedical concept corresponding to 'nf-kappa bp50'?
[ "nfkb-p50 (homo sapiens)", "nf-kappa-b1 (homo sapiens)", "nf-kb (homo sapiens)", "nfkb-p105 (homo sapiens)", "nuclear factor kappa b subunit 1 (homo sapiens)" ]
[ "rela proto-oncogene, nf-kb subunit (homo sapiens)", "rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens)", "nuclear factor kappa b subunit 2 (homo sapiens)", "relb proto-oncogene, nf-kb subunit (homo sapiens)" ]
Given the context 'The previously published assignments of c-rel and NF-kappa Bp50 have been refined to specific bands.', answer the user's query.
What is the biomedical concept corresponding to 'lyt-10'?
[ "lyt-10 (homo sapiens)", "lyt10 (homo sapiens)" ]
[ "interleukin 10 (homo sapiens)", "lyt-10 (xenopus tropicalis)", "ip-10 (homo sapiens)", "interleukin 1 family member 10 (homo sapiens)" ]
Given the context 'The map position of lyt-10, inferred from its isolation from a t(10;14)(q24;q32) translocation, has been confirmed.', answer the user's query.
What is the biomedical concept corresponding to 'nf-kappa bp65'?
[ "rela proto-oncogene, nf-kb subunit (homo sapiens)", "p65 (homo sapiens) (rela proto-oncogene, nf-kb subunit (homo sapiens))" ]
[ "nuclear factor kappa b subunit 2 (homo sapiens)", "nf-kb (homo sapiens)", "nf-kb2 (homo sapiens)", "nf-kappab (homo sapiens)" ]
Given the context 'NF-kappa Bp65 has now been mapped to 11q13, a site of frequent involvement in aberration in multiple tumor types.', answer the user's query.
What is the biomedical concept corresponding to 'valyl-trna synthetase'?
[ "valyl-trna synthetase 1 (homo sapiens)" ]
[ "valyl-trna synthetase / valine-trna ligase (valrs) (arabidopsis thaliana)", "valine--trna ligase (saccharomyces cerevisiae s288c)", "valyl-trna synthetase (drosophila melanogaster)", "valyl trna synthetase (arabidopsis thaliana)" ]
Given the context 'Cloning, sequencing and expression of a cDNA encoding mammalian valyl-tRNA synthetase. ', answer the user's query.
What is the biomedical concept corresponding to 'trsval'?
[ "trsval (rattus norvegicus)" ]
[ "valine--trna ligase (saccharomyces cerevisiae s288c)", "valyl-trna synthetase 1 (bos taurus)", "valyl-trna synthetase 1 (homo sapiens)", "valyl-trna synthetase / valine-trna ligase (valrs) (arabidopsis thaliana)" ]
Given the context 'A fragment of the cDNA encoding a rat valyl-tRNA synthetase (TrsVal)-like protein was cloned from a rat cDNA library in lambda gt11 using an oligodeoxyribonucleotide (oligo) probe.', answer the user's query.
What is the biomedical concept corresponding to 'trsval'?
[ "valyl-trna synthetase 1 (homo sapiens)" ]
[ "valine--trna ligase (saccharomyces cerevisiae s288c)", "valyl-trna synthetase 1 (bos taurus)", "valyl-trna synthetase / valine-trna ligase (valrs) (arabidopsis thaliana)", "valyl-trna synthetase / valine-trna ligase-like protein (arabidopsis thaliana)" ]
Given the context 'Three independent plaque clones containing the human TrsVal cDNA were then isolated from a lambda gt10 human erythroleukemia cDNA library using the rat cDNA fragment as the hybridization probe.', answer the user's query.
What is the biomedical concept corresponding to 'trsval'?
[ "valine--trna ligase (saccharomyces cerevisiae s288c)" ]
[ "valyl-trna synthetase 1 (bos taurus)", "valyl-trna synthetase 1 (homo sapiens)", "valyl-trna synthetase / valine-trna ligase (valrs) (arabidopsis thaliana)", "valyl-trna synthetase / valine-trna ligase-like protein (arabidopsis thaliana)" ]
Given the context 'The deduced 1051-amino-acid sequence shares 65% identity with yeast TrsVal, and contains a highly basic N-terminal region, a newly evolved protease-sensitive region in sequence close to the C terminus, and several sites for protein kinase C phosphorylation.', answer the user's query.
What is the biomedical concept corresponding to 'trsval'?
[ "valyl-trna synthetase 1 (homo sapiens)" ]
[ "valine--trna ligase (saccharomyces cerevisiae s288c)", "valyl-trna synthetase 1 (bos taurus)", "valyl-trna synthetase / valine-trna ligase (valrs) (arabidopsis thaliana)", "valyl-trna synthetase / valine-trna ligase-like protein (arabidopsis thaliana)" ]
Given the context 'A 3-kb cDNA fragment was sub-cloned into plasmid pSVL and expressed in COS-7 cells; up to a sevenfold increase in TrsVal activity was obtained.', answer the user's query.
What is the biomedical concept corresponding to 'trsval'?
[ "valyl-trna synthetase 1 (homo sapiens)" ]
[ "valine--trna ligase (saccharomyces cerevisiae s288c)", "valyl-trna synthetase 1 (bos taurus)", "valyl-trna synthetase / valine-trna ligase (valrs) (arabidopsis thaliana)", "valyl-trna synthetase / valine-trna ligase-like protein (arabidopsis thaliana)" ]
Given the context 'These results confirm the cloning and sequencing of a human TrsVal-encoding cDNA.', answer the user's query.
What is the biomedical concept corresponding to 'calmodulin-like protein clp'?
[ "calmodulin like 3 (homo sapiens)", "clp (homo sapiens) (calmodulin like 3 (homo sapiens))" ]
[ "calmodulin-like protein;ef-hand domain-containing protein (caenorhabditis elegans)", "calmodulin like 6 (homo sapiens)", "calmodulin like 4 (homo sapiens)", "calmodulin-like protein (arabidopsis thaliana)" ]
Given the context 'Localization of the intronless gene coding for calmodulin-like protein CLP to human chromosome 10p13-ter. ', answer the user's query.
What is the biomedical concept corresponding to 'calmodulin-like protein'?
[ "calmodulin like 3 (homo sapiens)" ]
[ "calmodulin-like protein (arabidopsis thaliana)", "calmodulin-like (glycine max)", "calmodulin-like protein;ef-hand domain-containing protein (caenorhabditis elegans)", "calmodulin like 5 (homo sapiens)" ]
Given the context 'The functional intronless gene coding for a calmodulin-like protein (CLP) has been localized to human chromosome 10p13-ter.', answer the user's query.
What is the biomedical concept corresponding to 'cytochrome p-450 family 4'?
[ "cyp4f (homo sapiens)", "cytochrome p450 family 4 subfamily f member 3 (homo sapiens)", "cyp4f3 (homo sapiens)" ]
[ "cytochrome p450, family 4, subfamily f, polypeptide 4 (rattus norvegicus)", "cytochrome p450 family 4 subfamily f member 8 (homo sapiens)", "cyp4f-se4[6:7:8] (homo sapiens)", "cyp4f44p (homo sapiens)" ]
Given the context 'A novel form of cytochrome P-450 family 4 in human polymorphonuclear leukocytes.', answer the user's query.
What is the biomedical concept corresponding to 'leukotriene b4 omega-hydroxylase'?
[ "ltb4h (homo sapiens)" ]
[ "leukotriene-b(4) omega-hydroxylase 2-like (bos taurus)", "lta4h (homo sapiens)", "ltb4dh (homo sapiens)", "leukotriene a-4 hydrolase-like (glycine max)" ]
Given the context 'cDNA cloning and expression of leukotriene B4 omega-hydroxylase. ', answer the user's query.
What is the biomedical concept corresponding to 'leukotriene b4 (ltb4) omega-hydroxylase'?
[ "ltb4h (homo sapiens)" ]
[ "lta4h (homo sapiens)", "leukotriene-b(4) omega-hydroxylase 2-like (bos taurus)", "ltb4dh (homo sapiens)", "leukotriene a4 hydrolase (homo sapiens)" ]
Given the context 'Isolation of cDNA clones for human leukotriene B4 (LTB4) omega-hydroxylase clearly demonstrates that the hydroxylase is a member of the cytochrome P-450 (CYP) superfamily.', answer the user's query.
What is the biomedical concept corresponding to 'ltb4 omega-hydroxylase'?
[ "ltb4h (homo sapiens)" ]
[ "lta4h (homo sapiens)", "arachidonate 5-lipoxygenase (homo sapiens)", "ltb4dh (homo sapiens)", "cyp2b4 (oryctolagus cuniculus)" ]
Given the context 'The microsomes from yeast cells transfected with an expression vector pAAH5 carrying isolated cDNA catalyzed the omega-hydroxylation of LTB4 with a Km value of 0.71 microM, and its activity was significantly inhibited by carbon monoxide and by antisera against CYP4A4, consistent with the properties previously reported with LTB4 omega-hydroxylase in human polymorphonuclear leukocytes.', answer the user's query.
What is the biomedical concept corresponding to 'ltb4 omega-hydroxylase'?
[ "ltb4h (homo sapiens)" ]
[ "lta4h (homo sapiens)", "arachidonate 5-lipoxygenase (homo sapiens)", "ltb4dh (homo sapiens)", "cyp2b4 (oryctolagus cuniculus)" ]
Given the context 'The amino acid sequence of LTB4 omega-hydroxylase (P-450LTB omega) shows 31-44% similarity to those of CYP4A, CYP4B, and CYP4C, whereas less than 25% similarity was observed with any of the other P-450 families.', answer the user's query.