query string | positive list | negative list | system string |
|---|---|---|---|
What is the biomedical concept corresponding to 'cnp'? | [
"cnp2 (homo sapiens)",
"cnp (homo sapiens) (natriuretic peptide c (homo sapiens))"
] | [
"cnp (xenopus tropicalis) (natriuretic peptide c (xenopus tropicalis))",
"cnp (xenopus laevis) (natriuretic peptide c s homeolog (xenopus laevis))",
"c-type natriuretic peptide-like (xenopus tropicalis)",
"cnp-3 (caenorhabditis elegans)"
] | Given the context 'TSC-22 significantly enhanced CNP promoter activity in GH3 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'tsc-22'? | [
"tsc22 (homo sapiens)"
] | [
"tsc-22 (mus musculus)",
"tsc-22 (xenopus tropicalis)",
"tsc-22 (drosophila melanogaster)",
"tsc-22 (rattus norvegicus)"
] | Given the context 'We further cloned a 1.8-kb full-length human TSC-22 cDNA from a fetal kidney cDNA library by a combination of polymerase chain reaction and the rapid amplification of the cDNA ends technique.', answer the user's query. |
What is the biomedical concept corresponding to 'tsc-22'? | [
"tsc22 (homo sapiens)"
] | [
"tsc-22 (mus musculus)",
"tsc-22 (xenopus tropicalis)",
"tsc-22 (drosophila melanogaster)",
"tsc-22 (rattus norvegicus)"
] | Given the context 'In adults, human TSC-22 mRNA was highly expressed in brain, lung and heart.', answer the user's query. |
What is the biomedical concept corresponding to 'tsc-22'? | [
"tsc22 (homo sapiens)"
] | [
"tsc-22 (mus musculus)",
"tsc-22 (xenopus tropicalis)",
"tsc-22 (drosophila melanogaster)",
"tsc-22 (rattus norvegicus)"
] | Given the context 'TSC-22 gene expression in GH3 and human aortic endothelial cells was stimulated by cytokines including TGF-beta, in correlation with the CNP mRNA increase.', answer the user's query. |
What is the biomedical concept corresponding to 'cnp'? | [
"cnp2 (homo sapiens)",
"cnp (homo sapiens) (natriuretic peptide c (homo sapiens))"
] | [
"cnp (xenopus tropicalis) (natriuretic peptide c (xenopus tropicalis))",
"cnp (xenopus laevis) (natriuretic peptide c s homeolog (xenopus laevis))",
"c-type natriuretic peptide-like (xenopus tropicalis)",
"cnp-3 (caenorhabditis elegans)"
] | Given the context 'TSC-22 gene expression in GH3 and human aortic endothelial cells was stimulated by cytokines including TGF-beta, in correlation with the CNP mRNA increase.', answer the user's query. |
What is the biomedical concept corresponding to 'tsc-22'? | [
"tsc22 (homo sapiens)"
] | [
"tsc-22 (mus musculus)",
"tsc-22 (xenopus tropicalis)",
"tsc-22 (drosophila melanogaster)",
"tsc-22 (rattus norvegicus)"
] | Given the context 'These results suggest that TSC-22 is a transcriptional regulator of the CNP gene and transmits signals from cytokines, such as TGF-beta, to CNP gene expression.', answer the user's query. |
What is the biomedical concept corresponding to 'cnp'? | [
"cnp2 (homo sapiens)",
"cnp (homo sapiens) (natriuretic peptide c (homo sapiens))"
] | [
"cnp (xenopus tropicalis) (natriuretic peptide c (xenopus tropicalis))",
"cnp (xenopus laevis) (natriuretic peptide c s homeolog (xenopus laevis))",
"c-type natriuretic peptide-like (xenopus tropicalis)",
"cnp-3 (caenorhabditis elegans)"
] | Given the context 'These results suggest that TSC-22 is a transcriptional regulator of the CNP gene and transmits signals from cytokines, such as TGF-beta, to CNP gene expression.', answer the user's query. |
What is the biomedical concept corresponding to 'cnp'? | [
"cnp2 (homo sapiens)",
"cnp (homo sapiens) (natriuretic peptide c (homo sapiens))"
] | [
"cnp (xenopus tropicalis) (natriuretic peptide c (xenopus tropicalis))",
"cnp (xenopus laevis) (natriuretic peptide c s homeolog (xenopus laevis))",
"c-type natriuretic peptide-like (xenopus tropicalis)",
"cnp-3 (caenorhabditis elegans)"
] | Given the context 'These results suggest that TSC-22 is a transcriptional regulator of the CNP gene and transmits signals from cytokines, such as TGF-beta, to CNP gene expression.', answer the user's query. |
What is the biomedical concept corresponding to 'rep-8'? | [
"rep8 (homo sapiens)"
] | [
"rep-8 (mus musculus)",
"rep8 (xenopus laevis)",
"rep8 (xenopus tropicalis)",
"rep-1 (homo sapiens)"
] | Given the context 'Cloning and characterization of Rep-8 (D8S2298E) in the human chromosome 8p11.2-p12.
', answer the user's query. |
What is the biomedical concept corresponding to 'd8s2298e'? | [
"d8s2298e (homo sapiens)"
] | [
"d0h8s2298e (mus musculus)",
"d17s978e (homo sapiens)",
"d6s228e (homo sapiens)",
"d18s892e (homo sapiens)"
] | Given the context 'Cloning and characterization of Rep-8 (D8S2298E) in the human chromosome 8p11.2-p12.
', answer the user's query. |
What is the biomedical concept corresponding to 'rep-8'? | [
"rep8 (homo sapiens)"
] | [
"rep-8 (mus musculus)",
"rep8 (xenopus laevis)",
"rep8 (xenopus tropicalis)",
"rep-1 (homo sapiens)"
] | Given the context 'A novel human gene referred to as the Rep-8 gene (D8S2298E) was cloned by a combination of exon trapping, thermal asymmetric interlaced-PCR, and screening of a cDNA library.', answer the user's query. |
What is the biomedical concept corresponding to 'd8s2298e'? | [
"d8s2298e (homo sapiens)"
] | [
"d0h8s2298e (mus musculus)",
"d17s978e (homo sapiens)",
"d6s228e (homo sapiens)",
"d18s892e (homo sapiens)"
] | Given the context 'A novel human gene referred to as the Rep-8 gene (D8S2298E) was cloned by a combination of exon trapping, thermal asymmetric interlaced-PCR, and screening of a cDNA library.', answer the user's query. |
What is the biomedical concept corresponding to 'glutathione s-reductase'? | [
"glutathione-disulfide reductase (homo sapiens)",
"gsr (homo sapiens)"
] | [
"glutathione-disulfide reductase (sus scrofa)",
"glutathione synthetase (homo sapiens)",
"gshs (homo sapiens)",
"glutathione reductase (glycine max)"
] | Given the context 'The gene consists of eight exons and spans about 20 kb between the glutathione S-reductase and the protein phosphatase 2A beta subunit genes.', answer the user's query. |
What is the biomedical concept corresponding to 'rep-8'? | [
"rep8 (homo sapiens)"
] | [
"rep-8 (mus musculus)",
"rep8 (xenopus laevis)",
"rep8 (xenopus tropicalis)",
"rep-1 (homo sapiens)"
] | Given the context 'The full-length Rep-8 gene contains 1483 nucleotides and codes for a protein of 270 amino acids.', answer the user's query. |
What is the biomedical concept corresponding to 'rep-8'? | [
"rep8 (homo sapiens)"
] | [
"rep-8 (mus musculus)",
"rep8 (xenopus laevis)",
"rep8 (xenopus tropicalis)",
"rep-1 (homo sapiens)"
] | Given the context 'Southern blot experiments showed that the Rep-8 gene exists as a single copy per haploid.', answer the user's query. |
What is the biomedical concept corresponding to 'rep-8'? | [
"rep8 (homo sapiens)"
] | [
"rep-8 (mus musculus)",
"rep8 (xenopus laevis)",
"rep8 (xenopus tropicalis)",
"rep-1 (homo sapiens)"
] | Given the context 'With a zoo blot analysis, human Rep-8 DNA hybridized strongly with the monkey DNA, but only weakly with the DNAs of species other than Homo sapiens.', answer the user's query. |
What is the biomedical concept corresponding to 'rep-8'? | [
"rep8 (homo sapiens)"
] | [
"rep-8 (mus musculus)",
"rep8 (xenopus laevis)",
"rep8 (xenopus tropicalis)",
"rep-1 (homo sapiens)"
] | Given the context 'Northern blot analysis showed that it is expressed abundantly in the testis and ovary, suggesting that the Rep-8 gene product may play a role in reproduction.', answer the user's query. |
What is the biomedical concept corresponding to 'kit'? | [
"kit proto-oncogene, receptor tyrosine kinase (homo sapiens)",
"c-kit (homo sapiens)",
"kit (homo sapiens)",
"cd117 (homo sapiens)"
] | [
"kit ligand (homo sapiens)",
"kit proto-oncogene receptor tyrosine kinase (mus musculus)",
"kit proto-oncogene, receptor tyrosine kinase (gallus gallus)",
"kitl (homo sapiens)"
] | Given the context 'Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes.
', answer the user's query. |
What is the biomedical concept corresponding to 'fms'? | [
"fms (homo sapiens)",
"c-fms (homo sapiens)",
"csf1r (homo sapiens)",
"colony stimulating factor 1 receptor (homo sapiens)"
] | [
"fms related receptor tyrosine kinase 1 (homo sapiens)",
"fms related receptor tyrosine kinase 3 (homo sapiens)",
"fms related receptor tyrosine kinase 4 (homo sapiens)",
"fms (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes.
', answer the user's query. |
What is the biomedical concept corresponding to 'kit'? | [
"kit proto-oncogene, receptor tyrosine kinase (homo sapiens)",
"c-kit (homo sapiens)",
"kit (homo sapiens)",
"cd117 (homo sapiens)"
] | [
"kit ligand (homo sapiens)",
"kit proto-oncogene receptor tyrosine kinase (mus musculus)",
"kit proto-oncogene, receptor tyrosine kinase (gallus gallus)",
"kitl (homo sapiens)"
] | Given the context 'The KIT and FMS tyrosine kinase receptors, which are implicated in the control of cell growth and differentiation, stem through duplications from a common ancestor.', answer the user's query. |
What is the biomedical concept corresponding to 'fms'? | [
"fms (homo sapiens)",
"c-fms (homo sapiens)",
"csf1r (homo sapiens)",
"colony stimulating factor 1 receptor (homo sapiens)"
] | [
"fms related receptor tyrosine kinase 1 (homo sapiens)",
"fms related receptor tyrosine kinase 3 (homo sapiens)",
"fms related receptor tyrosine kinase 4 (homo sapiens)",
"fms (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'The KIT and FMS tyrosine kinase receptors, which are implicated in the control of cell growth and differentiation, stem through duplications from a common ancestor.', answer the user's query. |
What is the biomedical concept corresponding to 'kit'? | [
"kit proto-oncogene, receptor tyrosine kinase (homo sapiens)",
"c-kit (homo sapiens)",
"kit (homo sapiens)",
"cd117 (homo sapiens)"
] | [
"kit ligand (homo sapiens)",
"kit proto-oncogene receptor tyrosine kinase (mus musculus)",
"kit proto-oncogene, receptor tyrosine kinase (gallus gallus)",
"kitl (homo sapiens)"
] | Given the context 'We have conducted a detailed structural analysis of the two loci containing the KIT and FMS genes.', answer the user's query. |
What is the biomedical concept corresponding to 'fms'? | [
"fms (homo sapiens)",
"c-fms (homo sapiens)",
"csf1r (homo sapiens)",
"colony stimulating factor 1 receptor (homo sapiens)"
] | [
"fms related receptor tyrosine kinase 1 (homo sapiens)",
"fms related receptor tyrosine kinase 3 (homo sapiens)",
"fms related receptor tyrosine kinase 4 (homo sapiens)",
"fms (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'We have conducted a detailed structural analysis of the two loci containing the KIT and FMS genes.', answer the user's query. |
What is the biomedical concept corresponding to 'kit'? | [
"kit proto-oncogene, receptor tyrosine kinase (homo sapiens)",
"c-kit (homo sapiens)",
"kit (homo sapiens)",
"cd117 (homo sapiens)"
] | [
"kit ligand (homo sapiens)",
"kit proto-oncogene receptor tyrosine kinase (mus musculus)",
"kit proto-oncogene, receptor tyrosine kinase (gallus gallus)",
"kitl (homo sapiens)"
] | Given the context 'The sequence of the approximately 90-kb KIT locus reveals the position and size of the 21 introns and of the 5' regulatory region of the KIT gene.', answer the user's query. |
What is the biomedical concept corresponding to 'kit'? | [
"kit proto-oncogene, receptor tyrosine kinase (homo sapiens)",
"c-kit (homo sapiens)",
"kit (homo sapiens)",
"cd117 (homo sapiens)"
] | [
"kit ligand (homo sapiens)",
"kit proto-oncogene receptor tyrosine kinase (mus musculus)",
"kit proto-oncogene, receptor tyrosine kinase (gallus gallus)",
"kitl (homo sapiens)"
] | Given the context 'The sequence of the approximately 90-kb KIT locus reveals the position and size of the 21 introns and of the 5' regulatory region of the KIT gene.', answer the user's query. |
What is the biomedical concept corresponding to 'kit'? | [
"kit proto-oncogene, receptor tyrosine kinase (homo sapiens)",
"c-kit (homo sapiens)",
"kit (homo sapiens)",
"cd117 (homo sapiens)"
] | [
"kit ligand (homo sapiens)",
"kit proto-oncogene receptor tyrosine kinase (mus musculus)",
"kit proto-oncogene, receptor tyrosine kinase (gallus gallus)",
"kitl (homo sapiens)"
] | Given the context 'The introns and the 3'-untranslated parts of KIT and FMS have been analyzed in parallel.', answer the user's query. |
What is the biomedical concept corresponding to 'fms'? | [
"fms (homo sapiens)",
"c-fms (homo sapiens)",
"csf1r (homo sapiens)",
"colony stimulating factor 1 receptor (homo sapiens)"
] | [
"fms related receptor tyrosine kinase 1 (homo sapiens)",
"fms related receptor tyrosine kinase 3 (homo sapiens)",
"fms related receptor tyrosine kinase 4 (homo sapiens)",
"fms (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'The introns and the 3'-untranslated parts of KIT and FMS have been analyzed in parallel.', answer the user's query. |
What is the biomedical concept corresponding to 'fms'? | [
"fms (homo sapiens)",
"c-fms (homo sapiens)",
"csf1r (homo sapiens)",
"colony stimulating factor 1 receptor (homo sapiens)"
] | [
"fms related receptor tyrosine kinase 1 (homo sapiens)",
"fms related receptor tyrosine kinase 3 (homo sapiens)",
"fms related receptor tyrosine kinase 4 (homo sapiens)",
"fms (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'These programs led us to identify a novel gene, designated SMF, immediately downstream of FMS, in the opposite orientation.', answer the user's query. |
What is the biomedical concept corresponding to '56 kda selenium binding protein'? | [
"selenium binding protein 1 (homo sapiens)",
"sbp56 (homo sapiens)",
"selenbp1 (homo sapiens)"
] | [
"sbp56 (xenopus laevis) (selenium binding protein 1 s homeolog (xenopus laevis))",
"sp56 (xenopus laevis) (selenium binding protein 1 s homeolog (xenopus laevis))",
"sbp56 (xenopus laevis) (selenium binding protein 1 l homeolog (xenopus laevis))",
"sp56 (xenopus laevis) (selenium binding protein 1 l homeolog ... | Given the context 'We have isolated the full-length human 56 kDa selenium binding protein (hSP56) cDNA clone, which is the human homolog of mouse 56 kDa selenium binding protein.', answer the user's query. |
What is the biomedical concept corresponding to 'hsp56'? | [
"sp56 (homo sapiens)",
"sbp56 (homo sapiens)"
] | [
"hsp56 (homo sapiens)",
"pp5656 (homo sapiens)",
"ppp1r56 (homo sapiens)",
"prss56 (homo sapiens)"
] | Given the context 'We have isolated the full-length human 56 kDa selenium binding protein (hSP56) cDNA clone, which is the human homolog of mouse 56 kDa selenium binding protein.', answer the user's query. |
What is the biomedical concept corresponding to '56 kda selenium binding protein'? | [
"selenium binding protein 1 (homo sapiens)",
"sbp56 (homo sapiens)",
"selenbp1 (homo sapiens)"
] | [
"sbp56 (xenopus laevis) (selenium binding protein 1 s homeolog (xenopus laevis))",
"sp56 (xenopus laevis) (selenium binding protein 1 s homeolog (xenopus laevis))",
"sbp56 (xenopus laevis) (selenium binding protein 1 l homeolog (xenopus laevis))",
"sp56 (xenopus laevis) (selenium binding protein 1 l homeolog ... | Given the context 'Using Northern blot hybridization, we found that this 56 kDa selenium binding protein is expressed in mouse heart with an intermediate level between those found in liver/lung/kidney and intestine.', answer the user's query. |
What is the biomedical concept corresponding to 'hsp56'? | [
"sp56 (homo sapiens)",
"sbp56 (homo sapiens)"
] | [
"hsp56 (homo sapiens)",
"pp5656 (homo sapiens)",
"ppp1r56 (homo sapiens)",
"prss56 (homo sapiens)"
] | Given the context 'We have also successfully expressed hSP56 in Escherichia coli using the expression vector-pAED4.', answer the user's query. |
What is the biomedical concept corresponding to 'hsp56'? | [
"sp56 (homo sapiens)",
"sbp56 (homo sapiens)"
] | [
"hsp56 (homo sapiens)",
"pp5656 (homo sapiens)",
"ppp1r56 (homo sapiens)",
"prss56 (homo sapiens)"
] | Given the context 'The hSP56 gene is located at human chromosome 1q21-22).', answer the user's query. |
What is the biomedical concept corresponding to 'pk428'? | [
"pk428 (homo sapiens)"
] | [
"pk428 (rattus norvegicus)",
"l(2)k05428 (drosophila melanogaster)",
"cell-pk42 (drosophila melanogaster)",
"cg32428 (drosophila melanogaster)"
] | Given the context 'We have cloned a novel serine/threonine protein kinase (PK428) which is highly related (65%) within the kinase domain to the myotonic dystrophy protein kinase (DM-PK), as well as the cyclic AMP-dependent protein kinase (33%).', answer the user's query. |
What is the biomedical concept corresponding to 'myotonic dystrophy protein kinase'? | [
"dm1 protein kinase (homo sapiens)",
"dm1pk (homo sapiens)",
"dm1 (homo sapiens) (dm1 protein kinase (homo sapiens))"
] | [
"dystrophia myotonica-protein kinase (mus musculus)",
"dm (mus musculus) (dystrophia myotonica-protein kinase (mus musculus))",
"deoxythymidylate kinase (mus musculus)",
"dm1 protein kinase (xenopus tropicalis)"
] | Given the context 'We have cloned a novel serine/threonine protein kinase (PK428) which is highly related (65%) within the kinase domain to the myotonic dystrophy protein kinase (DM-PK), as well as the cyclic AMP-dependent protein kinase (33%).', answer the user's query. |
What is the biomedical concept corresponding to 'pk428'? | [
"pk428 (homo sapiens)"
] | [
"pk428 (rattus norvegicus)",
"l(2)k05428 (drosophila melanogaster)",
"cell-pk42 (drosophila melanogaster)",
"cg32428 (drosophila melanogaster)"
] | Given the context 'Northern blots demonstrate that PK428 mRNA is distributed widely among tissues and is expressed at the highest levels in pancreas, heart, and skeletal muscle, with lower levels in liver and lung.', answer the user's query. |
What is the biomedical concept corresponding to 'pk428'? | [
"pk428 (homo sapiens)"
] | [
"pk428 (rattus norvegicus)",
"l(2)k05428 (drosophila melanogaster)",
"cell-pk42 (drosophila melanogaster)",
"cg32428 (drosophila melanogaster)"
] | Given the context 'Two PK428 mRNAs 10 and 3.8 kilobase pairs in size are seen in a number of cell lines, including hematopoietic and breast cancer cells.', answer the user's query. |
What is the biomedical concept corresponding to 'pk428'? | [
"pk428 (homo sapiens)"
] | [
"pk428 (rattus norvegicus)",
"l(2)k05428 (drosophila melanogaster)",
"cell-pk42 (drosophila melanogaster)",
"cg32428 (drosophila melanogaster)"
] | Given the context 'Immunoprecipitation of the transiently expressed PK428 protein and incubation with [gamma-32P]ATP demonstrate that it is capable of autophosphorylation.', answer the user's query. |
What is the biomedical concept corresponding to 'pk428'? | [
"pk428 (homo sapiens)"
] | [
"pk428 (rattus norvegicus)",
"l(2)k05428 (drosophila melanogaster)",
"cell-pk42 (drosophila melanogaster)",
"cg32428 (drosophila melanogaster)"
] | Given the context 'In addition, immunoprecipitates of the PK428 protein kinase also phosphorylated histone H1 and a peptide encoding a cyclic AMP-dependent protein kinase substrate.', answer the user's query. |
What is the biomedical concept corresponding to 'pk428'? | [
"pk428 (homo sapiens)"
] | [
"pk428 (rattus norvegicus)",
"l(2)k05428 (drosophila melanogaster)",
"cell-pk42 (drosophila melanogaster)",
"cg32428 (drosophila melanogaster)"
] | Given the context 'The gene corresponding to the 3.8-kb PK428 mRNA, and its corresponding 65-kDa protein, was isolated by polymerase chain reaction screening of a P1 phage human genomic library.', answer the user's query. |
What is the biomedical concept corresponding to 'pk428'? | [
"pk428 (homo sapiens)"
] | [
"pk428 (rattus norvegicus)",
"l(2)k05428 (drosophila melanogaster)",
"cell-pk42 (drosophila melanogaster)",
"cg32428 (drosophila melanogaster)"
] | Given the context 'Using this P1 phage clone as a probe, the PK428 gene was located on 1q41-42, a possible location for a human senescence gene, a gene associated with Rippling muscle disease, as well as a region associated with genetically acquired mental retardation.', answer the user's query. |
What is the biomedical concept corresponding to 'a gene associated with rippling muscle disease'? | [
"rippling muscle disease 1 (homo sapiens)",
"rmd1 (homo sapiens) (rippling muscle disease 1 (homo sapiens))"
] | [
"reactive intermediate imine deaminase a homolog (gallus gallus)",
"reactive intermediate imine deaminase a homolog (mus musculus)",
"adipose differentiation related protein, pseudogene (mus musculus)",
"peptidase domain containing associated with muscle regeneration 1 (mus musculus)"
] | Given the context 'Using this P1 phage clone as a probe, the PK428 gene was located on 1q41-42, a possible location for a human senescence gene, a gene associated with Rippling muscle disease, as well as a region associated with genetically acquired mental retardation.', answer the user's query. |
What is the biomedical concept corresponding to 'prk2'? | [
"prk2 (homo sapiens)",
"pkn2 (homo sapiens)",
"pak-2 (homo sapiens)"
] | [
"prka2 (homo sapiens)",
"pkc2 (homo sapiens)",
"pk2 (homo sapiens)",
"pkk2 (homo sapiens)"
] | Given the context 'Isolation and characterization of a structural homologue of human PRK2 from rat liver.', answer the user's query. |
What is the biomedical concept corresponding to 'protein kinase c (pkc)-related kinase-2'? | [
"prk2 (homo sapiens)",
"pkn2 (homo sapiens)",
"prkcl2 (homo sapiens)"
] | [
"g protein-coupled receptor kinase 2 (homo sapiens)",
"pkk2 (homo sapiens)",
"pkc2 (homo sapiens)",
"protein kinase c-like 2 (xenopus tropicalis)"
] | Given the context 'A homologue of human protein kinase C (PKC)-related kinase-2, PRK2, which had previously escaped identification in normal mammalian tissues, was isolated from rat liver as the protease-activated kinase (PAK) originally named PAK-2.', answer the user's query. |
What is the biomedical concept corresponding to 'prk2'? | [
"prk2 (homo sapiens)",
"pkn2 (homo sapiens)",
"pak-2 (homo sapiens)"
] | [
"prka2 (homo sapiens)",
"pkc2 (homo sapiens)",
"pk2 (homo sapiens)",
"pkk2 (homo sapiens)"
] | Given the context 'A homologue of human protein kinase C (PKC)-related kinase-2, PRK2, which had previously escaped identification in normal mammalian tissues, was isolated from rat liver as the protease-activated kinase (PAK) originally named PAK-2.', answer the user's query. |
What is the biomedical concept corresponding to '130-kda human pkc-related kinase'? | [
"stk7 (homo sapiens) (protein kinase n2 (homo sapiens))",
"protein kinase n2 (homo sapiens)"
] | [
"dnapkc (homo sapiens)",
"ndpkc (homo sapiens)",
"snf related kinase (homo sapiens)",
"p90-rsk2 (homo sapiens)"
] | Given the context 'The 130-kDa cytosolic enzyme was purified to homogeneity and shown by tryptic peptide and reverse transcriptase- polymerase chain reaction (RT-PCR)-amplified rat cDNA sequence analyses to be structurally related to the 116-kDa rat hepatic PAK-1/protein kinase N (PKN) and, even more closely (95% sequence identity) to the 130-kDa human PKC-related kinase, PRK2.', answer the user's query. |
What is the biomedical concept corresponding to 'prk2'? | [
"prk2 (homo sapiens)",
"pkn2 (homo sapiens)",
"pak-2 (homo sapiens)"
] | [
"prka2 (homo sapiens)",
"pkc2 (homo sapiens)",
"pk2 (homo sapiens)",
"pkk2 (homo sapiens)"
] | Given the context 'The 130-kDa cytosolic enzyme was purified to homogeneity and shown by tryptic peptide and reverse transcriptase- polymerase chain reaction (RT-PCR)-amplified rat cDNA sequence analyses to be structurally related to the 116-kDa rat hepatic PAK-1/protein kinase N (PKN) and, even more closely (95% sequence identity) to the 130-kDa human PKC-related kinase, PRK2.', answer the user's query. |
What is the biomedical concept corresponding to 'prk2'? | [
"prk2 (homo sapiens)",
"pkn2 (homo sapiens)",
"pak-2 (homo sapiens)"
] | [
"prka2 (homo sapiens)",
"pkc2 (homo sapiens)",
"pk2 (homo sapiens)",
"pkk2 (homo sapiens)"
] | Given the context 'Rat myeloma RNA was used as the RT-PCR template because of its relative abundance in PAK-2/PRK2 mRNA compared with liver and other rat tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'prk2'? | [
"prk2 (homo sapiens)",
"pkn2 (homo sapiens)",
"pak-2 (homo sapiens)"
] | [
"prka2 (homo sapiens)",
"pkc2 (homo sapiens)",
"pk2 (homo sapiens)",
"pkk2 (homo sapiens)"
] | Given the context 'The catalytic properties of PAK-2/PRK2 in many respects resembled those of hepatic PAK-1/PKN, but were distinguished by more favorable kinetics with several peptide substrates, and greater sensitivity to PKC pseudosubstrate and polybasic amino acid inhibitors.', answer the user's query. |
What is the biomedical concept corresponding to 'prk2'? | [
"prk2 (homo sapiens)",
"pkn2 (homo sapiens)",
"pak-2 (homo sapiens)"
] | [
"prka2 (homo sapiens)",
"pkc2 (homo sapiens)",
"pk2 (homo sapiens)",
"pkk2 (homo sapiens)"
] | Given the context 'PAK-2/PRK2 was also activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids.', answer the user's query. |
What is the biomedical concept corresponding to 'prk2'? | [
"prk2 (homo sapiens)",
"pkn2 (homo sapiens)",
"pak-2 (homo sapiens)"
] | [
"prka2 (homo sapiens)",
"pkc2 (homo sapiens)",
"pk2 (homo sapiens)",
"pkk2 (homo sapiens)"
] | Given the context 'It was concluded that PAK-2 is the rat homologue of human PRK2, with biochemical properties distinct from although overlapping those of the PAK-1/PKN/PRK1 isoform.', answer the user's query. |
What is the biomedical concept corresponding to 'prk1'? | [
"pkn1 (homo sapiens)",
"pkn-alpha (homo sapiens)",
"prk1 (homo sapiens) (protein kinase n1 (homo sapiens))",
"prkcl1 (homo sapiens)",
"pkn (homo sapiens)"
] | [
"prk (homo sapiens)",
"prka1 (homo sapiens)",
"prkn (homo sapiens)",
"prkaa1 (homo sapiens)"
] | Given the context 'It was concluded that PAK-2 is the rat homologue of human PRK2, with biochemical properties distinct from although overlapping those of the PAK-1/PKN/PRK1 isoform.', answer the user's query. |
What is the biomedical concept corresponding to 'dipeptidyl-peptidase i'? | [
"dpp-i (homo sapiens)",
"dppi (homo sapiens)",
"dpp1 (homo sapiens)"
] | [
"dipeptidyl peptidase family member 1 (caenorhabditis elegans)",
"dipeptidase 1 (homo sapiens)",
"dppii (homo sapiens)",
"tripeptidyl peptidase 1 (homo sapiens)"
] | Given the context 'Human dipeptidyl-peptidase I. Gene characterization, localization, and expression.
Dipeptidyl-peptidase I, a lysosomal cysteine proteinase, is important in intracellular degradation of proteins and appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells.', answer the user's query. |
What is the biomedical concept corresponding to 'dipeptidyl-peptidase i'? | [
"dpp-i (homo sapiens)",
"dppi (homo sapiens)",
"dpp1 (homo sapiens)"
] | [
"dipeptidyl peptidase family member 1 (caenorhabditis elegans)",
"dipeptidase 1 (homo sapiens)",
"dppii (homo sapiens)",
"tripeptidyl peptidase 1 (homo sapiens)"
] | Given the context 'Human dipeptidyl-peptidase I. Gene characterization, localization, and expression.
Dipeptidyl-peptidase I, a lysosomal cysteine proteinase, is important in intracellular degradation of proteins and appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells.', answer the user's query. |
What is the biomedical concept corresponding to 'dipeptidyl-peptidase i'? | [
"dpp-i (homo sapiens)",
"dppi (homo sapiens)",
"dpp1 (homo sapiens)"
] | [
"dipeptidyl peptidase family member 1 (caenorhabditis elegans)",
"dipeptidase 1 (homo sapiens)",
"dppii (homo sapiens)",
"tripeptidyl peptidase 1 (homo sapiens)"
] | Given the context 'In the present investigation the gene for dipeptidyl-peptidase I was cloned and characterized.', answer the user's query. |
What is the biomedical concept corresponding to 'dipeptidyl-peptidase i'? | [
"dpp-i (homo sapiens)",
"dppi (homo sapiens)",
"dpp1 (homo sapiens)"
] | [
"dipeptidyl peptidase family member 1 (caenorhabditis elegans)",
"dipeptidase 1 (homo sapiens)",
"dppii (homo sapiens)",
"tripeptidyl peptidase 1 (homo sapiens)"
] | Given the context 'Northern analyses demonstrated that the dipeptidyl-peptidase I message is expressed at high levels in lung, kidney, and placenta, at moderate to low levels in many organs, and at barely detectable levels in the brain, suggesting tissue-specific regulation.', answer the user's query. |
What is the biomedical concept corresponding to 'interleukin-2'? | [
"interleukin 2 (homo sapiens)",
"il-2 (homo sapiens)",
"il2 (homo sapiens)"
] | [
"ilf2 (homo sapiens)",
"colony stimulating factor 2 (homo sapiens)",
"csf2 (homo sapiens)",
"il22 (homo sapiens)"
] | Given the context 'Treatment of lymphocytes with interleukin-2 resulted in a significant increase in dipeptidyl-peptidase I mRNA levels, suggesting that this gene is subjected to transcriptional regulation.', answer the user's query. |
What is the biomedical concept corresponding to 'dipeptidyl-peptidase i'? | [
"dpp-i (homo sapiens)",
"dppi (homo sapiens)",
"dpp1 (homo sapiens)"
] | [
"dipeptidyl peptidase family member 1 (caenorhabditis elegans)",
"dipeptidase 1 (homo sapiens)",
"dppii (homo sapiens)",
"tripeptidyl peptidase 1 (homo sapiens)"
] | Given the context 'Treatment of lymphocytes with interleukin-2 resulted in a significant increase in dipeptidyl-peptidase I mRNA levels, suggesting that this gene is subjected to transcriptional regulation.', answer the user's query. |
What is the biomedical concept corresponding to 'dipeptidyl-peptidase i'? | [
"dpp-i (homo sapiens)",
"dppi (homo sapiens)",
"dpp1 (homo sapiens)"
] | [
"dipeptidyl peptidase family member 1 (caenorhabditis elegans)",
"dipeptidase 1 (homo sapiens)",
"dppii (homo sapiens)",
"tripeptidyl peptidase 1 (homo sapiens)"
] | Given the context 'The results provide initial insights into the molecular basis for the regulation of human dipeptidyl-peptidase I.', answer the user's query. |
What is the biomedical concept corresponding to 'osteoprotegerin'? | [
"opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens))"
] | [
"rankl (homo sapiens)",
"opgl (homo sapiens)",
"trailr-1 (homo sapiens)",
"tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (mus musculus)"
] | Given the context 'Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.
', answer the user's query. |
What is the biomedical concept corresponding to 'osteoprotegerin'? | [
"opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens))"
] | [
"rankl (homo sapiens)",
"opgl (homo sapiens)",
"trailr-1 (homo sapiens)",
"tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (mus musculus)"
] | Given the context 'The protein, termed Osteoprotegerin (OPG), is a novel member of the TNF receptor superfamily.', answer the user's query. |
What is the biomedical concept corresponding to 'opg'? | [
"opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens))"
] | [
"opgl (homo sapiens)",
"opgl (rattus norvegicus)",
"opg (rattus norvegicus)",
"rankl (homo sapiens)"
] | Given the context 'The protein, termed Osteoprotegerin (OPG), is a novel member of the TNF receptor superfamily.', answer the user's query. |
What is the biomedical concept corresponding to 'opg'? | [
"opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens))"
] | [
"opgl (homo sapiens)",
"opgl (rattus norvegicus)",
"opg (rattus norvegicus)",
"rankl (homo sapiens)"
] | Given the context 'In vivo, hepatic expression of OPG in transgenic mice results in a profound yet nonlethal osteopetrosis, coincident with a decrease in later stages of osteoclast differentiation.', answer the user's query. |
What is the biomedical concept corresponding to 'opg'? | [
"opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens))"
] | [
"opgl (homo sapiens)",
"opgl (rattus norvegicus)",
"opg (rattus norvegicus)",
"rankl (homo sapiens)"
] | Given the context 'These same effects are observed upon administration of recombinant OPG into normal mice.', answer the user's query. |
What is the biomedical concept corresponding to 'opg'? | [
"opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens))"
] | [
"opgl (homo sapiens)",
"opgl (rattus norvegicus)",
"opg (rattus norvegicus)",
"rankl (homo sapiens)"
] | Given the context 'In vitro, osteoclast differentiation from precursor cells is blocked in a dose-dependent manner by recombinant OPG.', answer the user's query. |
What is the biomedical concept corresponding to 'opg'? | [
"opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens))"
] | [
"opgl (homo sapiens)",
"opgl (rattus norvegicus)",
"opg (rattus norvegicus)",
"rankl (homo sapiens)"
] | Given the context 'Furthermore, OPG blocks ovariectomy-associated bone loss in rats.', answer the user's query. |
What is the biomedical concept corresponding to 'opg'? | [
"opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens))"
] | [
"opgl (homo sapiens)",
"opgl (rattus norvegicus)",
"opg (rattus norvegicus)",
"rankl (homo sapiens)"
] | Given the context 'These data show that OPG can act as a soluble factor in the regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity.', answer the user's query. |
What is the biomedical concept corresponding to 'opg'? | [
"opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens))"
] | [
"opgl (homo sapiens)",
"opgl (rattus norvegicus)",
"opg (rattus norvegicus)",
"rankl (homo sapiens)"
] | Given the context 'These data show that OPG can act as a soluble factor in the regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity.', answer the user's query. |
What is the biomedical concept corresponding to 'rhohp1'? | [
"rhohp1 (homo sapiens)"
] | [
"rho (drosophila melanogaster) (rho1 (drosophila melanogaster))",
"rho family gtpase 1 (homo sapiens)",
"rhoh (homo sapiens)",
"rhox homeobox family member 1 (homo sapiens)"
] | Given the context 'Isolation of a novel human cDNA (rhoHP1) homologous to rho genes.
', answer the user's query. |
What is the biomedical concept corresponding to 'rhohp1'? | [
"rhohp1 (homo sapiens)"
] | [
"rho (drosophila melanogaster) (rho1 (drosophila melanogaster))",
"rho family gtpase 1 (homo sapiens)",
"rhoh (homo sapiens)",
"rhox homeobox family member 1 (homo sapiens)"
] | Given the context 'In view of its degree of homology to members of the Rho family of molecules (50-54% identical amino acids, 60-63% identical nucleotides within the coding region), the predicted product was designated RhoHP1(Rho-related protein HP1).', answer the user's query. |
What is the biomedical concept corresponding to 'rho-related protein hp1'? | [
"rhohp1 (homo sapiens)"
] | [
"rhoh (homo sapiens)",
"rhoc (homo sapiens)",
"rho family gtpase 1 (homo sapiens)",
"rho family gtpase 2 (homo sapiens)"
] | Given the context 'In view of its degree of homology to members of the Rho family of molecules (50-54% identical amino acids, 60-63% identical nucleotides within the coding region), the predicted product was designated RhoHP1(Rho-related protein HP1).', answer the user's query. |
What is the biomedical concept corresponding to 'i kappa b epsilon'? | [
"inhibitor of nuclear factor kappa b kinase subunit epsilon (homo sapiens)",
"ikk-e (homo sapiens)"
] | [
"i-kappa-b-epsilon (mus musculus)",
"nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus)",
"nfkb inhibitor epsilon (homo sapiens)",
"nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis)"
] | Given the context 'I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity.
', answer the user's query. |
What is the biomedical concept corresponding to 'rela'? | [
"rela (homo sapiens)",
"rela proto-oncogene, nf-kb subunit (homo sapiens)",
"p65 (homo sapiens) (rela proto-oncogene, nf-kb subunit (homo sapiens))"
] | [
"rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens)",
"rel proto-oncogene, nf-kb subunit (homo sapiens)",
"v-rel avian reticuloendotheliosis viral oncogene homolog (xenopus tropicalis)",
"nf-kappab (homo sapiens)"
] | Given the context 'I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity.
', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kappa b'? | [
"nf-kb (homo sapiens)",
"nf-kappab (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"nuclear factor kappa b subunit 1 (homo sapiens)",
"nf-kappabeta (homo sapiens)"
] | [
"rela proto-oncogene, nf-kb subunit (homo sapiens)",
"nuclear factor kappa b subunit 2 (homo sapiens)",
"relb proto-oncogene, nf-kb subunit (homo sapiens)",
"nfkbib (homo sapiens)"
] | Given the context 'I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity.
', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kappa b'? | [
"nf-kb (homo sapiens)",
"nf-kappab (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"nuclear factor kappa b subunit 1 (homo sapiens)",
"nf-kappabeta (homo sapiens)"
] | [
"rela proto-oncogene, nf-kb subunit (homo sapiens)",
"nuclear factor kappa b subunit 2 (homo sapiens)",
"relb proto-oncogene, nf-kb subunit (homo sapiens)",
"nfkbib (homo sapiens)"
] | Given the context 'We have isolated a human cDNA which encodes a novel I kappa B family member using a yeast two-hybrid screen for proteins able to interact with the p52 subunit of the transcription factor NF-kappa B.', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kappa b'? | [
"nf-kb (homo sapiens)",
"nf-kappab (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"nuclear factor kappa b subunit 1 (homo sapiens)",
"nf-kappabeta (homo sapiens)"
] | [
"rela proto-oncogene, nf-kb subunit (homo sapiens)",
"nuclear factor kappa b subunit 2 (homo sapiens)",
"relb proto-oncogene, nf-kb subunit (homo sapiens)",
"nfkbib (homo sapiens)"
] | Given the context 'The protein is found in many cell types and its expression is up-regulated following NF-kappa B activation and during myelopoiesis.', answer the user's query. |
What is the biomedical concept corresponding to 'i kappa b-epsilon'? | [
"inhibitor of nuclear factor kappa b kinase subunit epsilon (homo sapiens)",
"ikk-e (homo sapiens)"
] | [
"i-kappa-b-epsilon (mus musculus)",
"nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus)",
"nfkb inhibitor epsilon (homo sapiens)",
"nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis)"
] | Given the context 'Consistent with its proposed role as an I kappa B molecule, I kappa B-epsilon is able to inhibit NF-kappa B-directed transactivation via cytoplasmic retention of rel proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kappa b'? | [
"nf-kb (homo sapiens)",
"nf-kappab (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"nuclear factor kappa b subunit 1 (homo sapiens)",
"nf-kappabeta (homo sapiens)"
] | [
"rela proto-oncogene, nf-kb subunit (homo sapiens)",
"nuclear factor kappa b subunit 2 (homo sapiens)",
"relb proto-oncogene, nf-kb subunit (homo sapiens)",
"nfkbib (homo sapiens)"
] | Given the context 'Consistent with its proposed role as an I kappa B molecule, I kappa B-epsilon is able to inhibit NF-kappa B-directed transactivation via cytoplasmic retention of rel proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'i kappa b-epsilon'? | [
"inhibitor of nuclear factor kappa b kinase subunit epsilon (homo sapiens)",
"ikk-e (homo sapiens)"
] | [
"i-kappa-b-epsilon (mus musculus)",
"nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus)",
"nfkb inhibitor epsilon (homo sapiens)",
"nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis)"
] | Given the context 'I kappa B-epsilon translation initiates from an internal ATG codon to give rise to a protein of 45 kDa, which exists as multiple phosphorylated isoforms in resting cells.', answer the user's query. |
What is the biomedical concept corresponding to 'rela'? | [
"rela (homo sapiens)",
"rela proto-oncogene, nf-kb subunit (homo sapiens)",
"p65 (homo sapiens) (rela proto-oncogene, nf-kb subunit (homo sapiens))"
] | [
"rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens)",
"rel proto-oncogene, nf-kb subunit (homo sapiens)",
"v-rel avian reticuloendotheliosis viral oncogene homolog (xenopus tropicalis)",
"nf-kappab (homo sapiens)"
] | Given the context 'Unlike the other inhibitors, it is found almost exclusively in complexes containing RelA and/or cRel.', answer the user's query. |
What is the biomedical concept corresponding to 'i kappa b-epsilon'? | [
"inhibitor of nuclear factor kappa b kinase subunit epsilon (homo sapiens)",
"ikk-e (homo sapiens)"
] | [
"i-kappa-b-epsilon (mus musculus)",
"nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus)",
"nfkb inhibitor epsilon (homo sapiens)",
"nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis)"
] | Given the context 'Upon activation, I kappa B-epsilon protein is degraded with slow kinetics by a proteasome-dependent mechanism.', answer the user's query. |
What is the biomedical concept corresponding to 'i kappa b-alpha'? | [
"nfkbia (homo sapiens)",
"nfkbi (homo sapiens)",
"ikba (homo sapiens)"
] | [
"nuclear factor kappa b subunit 1 (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"ikka (homo sapiens)",
"rela proto-oncogene, nf-kb subunit (homo sapiens)"
] | Given the context 'Similarly to I kappa B-alpha', answer the user's query. |
What is the biomedical concept corresponding to 'i kappa b-epsilon'? | [
"inhibitor of nuclear factor kappa b kinase subunit epsilon (homo sapiens)",
"ikk-e (homo sapiens)"
] | [
"i-kappa-b-epsilon (mus musculus)",
"nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus)",
"nfkb inhibitor epsilon (homo sapiens)",
"nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis)"
] | Given the context 'and I kappa B, I kappa B-epsilon contains multiple ankyrin repeats and two conserved serines which are necessary for signal-induced degradation of the molecule.', answer the user's query. |
What is the biomedical concept corresponding to 'i kappa b- alpha'? | [
"nfkbia (homo sapiens)",
"nfkbi (homo sapiens)",
"ikba (homo sapiens)"
] | [
"nuclear factor kappa b subunit 1 (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"ikka (homo sapiens)",
"rela proto-oncogene, nf-kb subunit (homo sapiens)"
] | Given the context 'Unlike I kappa B- alpha and I kappa B-beta, I kappa B-epsilon does not contain a C-terminal PEST-like sequence.', answer the user's query. |
What is the biomedical concept corresponding to 'i kappa b-beta'? | [
"nfkbib (homo sapiens)",
"nfkb inhibitor beta (homo sapiens)"
] | [
"ikkb (homo sapiens)",
"ikk-beta (homo sapiens)",
"nuclear factor kappa b subunit 2 (homo sapiens)",
"nfkbi (homo sapiens)"
] | Given the context 'Unlike I kappa B- alpha and I kappa B-beta, I kappa B-epsilon does not contain a C-terminal PEST-like sequence.', answer the user's query. |
What is the biomedical concept corresponding to 'i kappa b-epsilon'? | [
"inhibitor of nuclear factor kappa b kinase subunit epsilon (homo sapiens)",
"ikk-e (homo sapiens)"
] | [
"i-kappa-b-epsilon (mus musculus)",
"nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus)",
"nfkb inhibitor epsilon (homo sapiens)",
"nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis)"
] | Given the context 'Unlike I kappa B- alpha and I kappa B-beta, I kappa B-epsilon does not contain a C-terminal PEST-like sequence.', answer the user's query. |
What is the biomedical concept corresponding to 'i kappa b-epsilon'? | [
"inhibitor of nuclear factor kappa b kinase subunit epsilon (homo sapiens)",
"ikk-e (homo sapiens)"
] | [
"i-kappa-b-epsilon (mus musculus)",
"nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus)",
"nfkb inhibitor epsilon (homo sapiens)",
"nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis)"
] | Given the context 'I kappa B-epsilon would, therefore, appear to regulate a late, transient activation of a subset of genes, regulated by RelA/cRel NF-kappa B complexes, distinct from those regulated by other I kappa B proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'rela'? | [
"rela (homo sapiens)",
"rela proto-oncogene, nf-kb subunit (homo sapiens)",
"p65 (homo sapiens) (rela proto-oncogene, nf-kb subunit (homo sapiens))"
] | [
"rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens)",
"rel proto-oncogene, nf-kb subunit (homo sapiens)",
"v-rel avian reticuloendotheliosis viral oncogene homolog (xenopus tropicalis)",
"nf-kappab (homo sapiens)"
] | Given the context 'I kappa B-epsilon would, therefore, appear to regulate a late, transient activation of a subset of genes, regulated by RelA/cRel NF-kappa B complexes, distinct from those regulated by other I kappa B proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kappa b'? | [
"nf-kb (homo sapiens)",
"nf-kappab (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"nuclear factor kappa b subunit 1 (homo sapiens)",
"nf-kappabeta (homo sapiens)"
] | [
"rela proto-oncogene, nf-kb subunit (homo sapiens)",
"nuclear factor kappa b subunit 2 (homo sapiens)",
"relb proto-oncogene, nf-kb subunit (homo sapiens)",
"nfkbib (homo sapiens)"
] | Given the context 'I kappa B-epsilon would, therefore, appear to regulate a late, transient activation of a subset of genes, regulated by RelA/cRel NF-kappa B complexes, distinct from those regulated by other I kappa B proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'vps41'? | [
"vps41p (saccharomyces cerevisiae s288c)",
"vps41 (saccharomyces cerevisiae s288c)"
] | [
"vacuolar protein sorting-associated protein 41 homolog (caenorhabditis elegans)",
"vps41 (homo sapiens)",
"vps41 subunit of hops complex (homo sapiens)",
"transmembrane protein 41 homolog (caenorhabditis elegans)"
] | Given the context 'Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast.
', answer the user's query. |
What is the biomedical concept corresponding to 'vps41'? | [
"vps41p (saccharomyces cerevisiae s288c)",
"vps41 (saccharomyces cerevisiae s288c)"
] | [
"vacuolar protein sorting-associated protein 41 homolog (caenorhabditis elegans)",
"vps41 (homo sapiens)",
"vps41 subunit of hops complex (homo sapiens)",
"transmembrane protein 41 homolog (caenorhabditis elegans)"
] | Given the context 'Mutations in the yeast gene VPS41 give rise to poor growth on low iron medium, severe alterations in vacuolar morphology, and cause the missorting of membranous and soluble vacuolar proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'vps41'? | [
"vps41p (saccharomyces cerevisiae s288c)",
"vps41 (saccharomyces cerevisiae s288c)"
] | [
"vacuolar protein sorting-associated protein 41 homolog (caenorhabditis elegans)",
"vps41 (homo sapiens)",
"vps41 subunit of hops complex (homo sapiens)",
"transmembrane protein 41 homolog (caenorhabditis elegans)"
] | Given the context 'Our studies predict that VPS41 encodes a hydrophilic protein of 992 amino acids that contains no obvious signal sequence or hydrophobic domains.', answer the user's query. |
What is the biomedical concept corresponding to 'vps41p'? | [
"vps41p (saccharomyces cerevisiae s288c)",
"vps41 (saccharomyces cerevisiae s288c)"
] | [
"hvps41p (homo sapiens)",
"vacuolar protein sorting-associated protein 41 homolog (caenorhabditis elegans)",
"vps41 (homo sapiens)",
"vps41p (candida albicans sc5314)"
] | Given the context 'The deduced Vps41p sequence contains a domain rich in glutamic and aspartic residues, as well as a domain with resemblance to a region of clathrin heavy chain.', answer the user's query. |
What is the biomedical concept corresponding to 'vps41'? | [
"vps41p (saccharomyces cerevisiae s288c)",
"vps41 (saccharomyces cerevisiae s288c)"
] | [
"vacuolar protein sorting-associated protein 41 homolog (caenorhabditis elegans)",
"vps41 (homo sapiens)",
"vps41 subunit of hops complex (homo sapiens)",
"transmembrane protein 41 homolog (caenorhabditis elegans)"
] | Given the context 'The VPS41 homologues (but not the yeast VPS41 itself) contain a conserved cysteine-rich RING-H2 zinc finger at their COOH termini.', answer the user's query. |
What is the biomedical concept corresponding to 'vps41'? | [
"vps41p (saccharomyces cerevisiae s288c)",
"vps41 (saccharomyces cerevisiae s288c)"
] | [
"vacuolar protein sorting-associated protein 41 homolog (caenorhabditis elegans)",
"vps41 (homo sapiens)",
"vps41 subunit of hops complex (homo sapiens)",
"transmembrane protein 41 homolog (caenorhabditis elegans)"
] | Given the context 'The VPS41 homologues (but not the yeast VPS41 itself) contain a conserved cysteine-rich RING-H2 zinc finger at their COOH termini.', answer the user's query. |
What is the biomedical concept corresponding to 'vps41'? | [
"vps41p (saccharomyces cerevisiae s288c)",
"vps41 (saccharomyces cerevisiae s288c)"
] | [
"vacuolar protein sorting-associated protein 41 homolog (caenorhabditis elegans)",
"vps41 (homo sapiens)",
"vps41 subunit of hops complex (homo sapiens)",
"transmembrane protein 41 homolog (caenorhabditis elegans)"
] | Given the context 'Biochemical experiments suggest that VPS41 functions in post-Golgi protein processing: the deletion mutant exhibits defective high affinity transport due to impaired Fet3p activity and also exhibits defects in the processing and sorting of multiple vacuolar hydrolases.', answer the user's query. |
What is the biomedical concept corresponding to 'fet3p'? | [
"fet3 (saccharomyces cerevisiae s288c)",
"ferroxidase fet3 (saccharomyces cerevisiae s288c)"
] | [
"fer3 (drosophila melanogaster) (ferritin 3 heavy chain homologue (drosophila melanogaster))",
"etf1p3 (homo sapiens)",
"fthl3p (homo sapiens)",
"fer3-like bhlh transcription factor (xenopus tropicalis)"
] | Given the context 'Biochemical experiments suggest that VPS41 functions in post-Golgi protein processing: the deletion mutant exhibits defective high affinity transport due to impaired Fet3p activity and also exhibits defects in the processing and sorting of multiple vacuolar hydrolases.', answer the user's query. |
What is the biomedical concept corresponding to 'wnt7a'? | [
"wnt7a (homo sapiens)",
"wnt family member 7a (homo sapiens)",
"wnt-7a (homo sapiens)"
] | [
"wnt family member 7a (gallus gallus)",
"wnt family member 7a (xenopus tropicalis)",
"wnt family member 7b (homo sapiens)",
"wnt7a (gallus gallus)"
] | Given the context 'Isolation of a full-length human WNT7A gene implicated in limb development and cell transformation, and mapping to chromosome 3p25.
', answer the user's query. |
What is the biomedical concept corresponding to 'wnt7a'? | [
"wnt7a (homo sapiens)",
"wnt family member 7a (homo sapiens)",
"wnt-7a (homo sapiens)"
] | [
"wnt family member 7a (gallus gallus)",
"wnt family member 7a (xenopus tropicalis)",
"wnt family member 7b (homo sapiens)",
"wnt7a (gallus gallus)"
] | Given the context 'One mouse member, Wnt7a, is vital for limb development in vivo and also possesses transforming ability in vitro.', answer the user's query. |
What is the biomedical concept corresponding to 'wnt7a'? | [
"wnt7a (homo sapiens)",
"wnt family member 7a (homo sapiens)",
"wnt-7a (homo sapiens)"
] | [
"wnt family member 7a (gallus gallus)",
"wnt family member 7a (xenopus tropicalis)",
"wnt family member 7b (homo sapiens)",
"wnt7a (gallus gallus)"
] | Given the context 'This study reports the isolation of a full length of human homologue of mouse Wnt7a gene by library screening.', answer the user's query. |
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