query
string
positive
list
negative
list
system
string
What is the biomedical concept corresponding to 'wnt7a'?
[ "wnt7a (homo sapiens)", "wnt family member 7a (homo sapiens)", "wnt-7a (homo sapiens)" ]
[ "wnt family member 7a (gallus gallus)", "wnt family member 7a (xenopus tropicalis)", "wnt family member 7b (homo sapiens)", "wnt7a (gallus gallus)" ]
Given the context 'Yeast artificial chromosome-fluorescence in situ hybridisation (YAC-FISH) mapped the WNT7A gene to chromosome 3p25.', answer the user's query.
What is the biomedical concept corresponding to 'wnt7a'?
[ "wnt7a (homo sapiens)", "wnt family member 7a (homo sapiens)", "wnt-7a (homo sapiens)" ]
[ "wnt family member 7a (gallus gallus)", "wnt family member 7a (xenopus tropicalis)", "wnt family member 7b (homo sapiens)", "wnt7a (gallus gallus)" ]
Given the context 'Human WNT7A had an ORF encoding a deduced protein of 349 aa that exhibited 97% and 92% identity to mouse Wnt7a at the aa and nucleic acid levels, respectively.', answer the user's query.
What is the biomedical concept corresponding to 'wnt7a'?
[ "wnt7a (homo sapiens)", "wnt family member 7a (homo sapiens)", "wnt-7a (homo sapiens)" ]
[ "wnt family member 7a (gallus gallus)", "wnt family member 7a (xenopus tropicalis)", "wnt family member 7b (homo sapiens)", "wnt7a (gallus gallus)" ]
Given the context 'Human WNT7A had an ORF encoding a deduced protein of 349 aa that exhibited 97% and 92% identity to mouse Wnt7a at the aa and nucleic acid levels, respectively.', answer the user's query.
What is the biomedical concept corresponding to 'smad7'?
[ "smad family member 7 (homo sapiens)", "smad7 (homo sapiens)" ]
[ "smad family member 7 (mus musculus)", "smad7 (mus musculus)", "smad7 (drosophila melanogaster)", "smad family member 6 (homo sapiens)" ]
Given the context 'The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. ', answer the user's query.
What is the biomedical concept corresponding to 'smad2'?
[ "smad2 (homo sapiens)", "smad family member 2 (homo sapiens)", "hsmad2 (homo sapiens) (smad family member 2 (homo sapiens))", "madr2 (homo sapiens)", "madh2 (homo sapiens)" ]
[ "smad2 (mus musculus)", "smad family member 2 (mus musculus)", "smad-2 (mus musculus)", "smad2 (drosophila melanogaster)" ]
Given the context 'TGFbeta signaling is initiated when the type I receptor phosphorylates the MAD-related protein, Smad2, on C-terminal serine residues.', answer the user's query.
What is the biomedical concept corresponding to 'smad2'?
[ "smad2 (homo sapiens)", "smad family member 2 (homo sapiens)", "hsmad2 (homo sapiens) (smad family member 2 (homo sapiens))", "madr2 (homo sapiens)", "madh2 (homo sapiens)" ]
[ "smad2 (mus musculus)", "smad family member 2 (mus musculus)", "smad-2 (mus musculus)", "smad2 (drosophila melanogaster)" ]
Given the context 'This leads to Smad2 association with Smad4, translocation to the nucleus, and regulation of transcriptional responses.', answer the user's query.
What is the biomedical concept corresponding to 'smad4'?
[ "smad4 (homo sapiens)", "smad family member 4 (homo sapiens)", "dpc4 (homo sapiens)", "madh4 (homo sapiens)" ]
[ "smad4 (mus musculus)", "smad family member 4 (mus musculus)", "smad family member 5 (homo sapiens)", "smad family member 4 (xenopus tropicalis)" ]
Given the context 'This leads to Smad2 association with Smad4, translocation to the nucleus, and regulation of transcriptional responses.', answer the user's query.
What is the biomedical concept corresponding to 'smad7'?
[ "smad family member 7 (homo sapiens)", "smad7 (homo sapiens)" ]
[ "smad family member 7 (mus musculus)", "smad7 (mus musculus)", "smad7 (drosophila melanogaster)", "smad family member 6 (homo sapiens)" ]
Given the context 'Here we demonstrate that Smad7 is an inhibitor of TGFbeta signaling.', answer the user's query.
What is the biomedical concept corresponding to 'smad7'?
[ "smad family member 7 (homo sapiens)", "smad7 (homo sapiens)" ]
[ "smad family member 7 (mus musculus)", "smad7 (mus musculus)", "smad7 (drosophila melanogaster)", "smad family member 6 (homo sapiens)" ]
Given the context 'Smad7 prevents TGFbeta-dependent formation of Smad2/Smad4 complexes and inhibits the nuclear accumulation of Smad2.', answer the user's query.
What is the biomedical concept corresponding to 'smad2'?
[ "smad2 (homo sapiens)", "smad family member 2 (homo sapiens)", "hsmad2 (homo sapiens) (smad family member 2 (homo sapiens))", "madr2 (homo sapiens)", "madh2 (homo sapiens)" ]
[ "smad2 (mus musculus)", "smad family member 2 (mus musculus)", "smad-2 (mus musculus)", "smad2 (drosophila melanogaster)" ]
Given the context 'Smad7 prevents TGFbeta-dependent formation of Smad2/Smad4 complexes and inhibits the nuclear accumulation of Smad2.', answer the user's query.
What is the biomedical concept corresponding to 'smad4'?
[ "smad4 (homo sapiens)", "smad family member 4 (homo sapiens)", "dpc4 (homo sapiens)", "madh4 (homo sapiens)" ]
[ "smad4 (mus musculus)", "smad family member 4 (mus musculus)", "smad family member 5 (homo sapiens)", "smad family member 4 (xenopus tropicalis)" ]
Given the context 'Smad7 prevents TGFbeta-dependent formation of Smad2/Smad4 complexes and inhibits the nuclear accumulation of Smad2.', answer the user's query.
What is the biomedical concept corresponding to 'smad2'?
[ "smad2 (homo sapiens)", "smad family member 2 (homo sapiens)", "hsmad2 (homo sapiens) (smad family member 2 (homo sapiens))", "madr2 (homo sapiens)", "madh2 (homo sapiens)" ]
[ "smad2 (mus musculus)", "smad family member 2 (mus musculus)", "smad-2 (mus musculus)", "smad2 (drosophila melanogaster)" ]
Given the context 'Smad7 prevents TGFbeta-dependent formation of Smad2/Smad4 complexes and inhibits the nuclear accumulation of Smad2.', answer the user's query.
What is the biomedical concept corresponding to 'smad7'?
[ "smad family member 7 (homo sapiens)", "smad7 (homo sapiens)" ]
[ "smad family member 7 (mus musculus)", "smad7 (mus musculus)", "smad7 (drosophila melanogaster)", "smad family member 6 (homo sapiens)" ]
Given the context 'Smad7 interacts stably with the activated TGFbeta type I receptor, thereby blocking the association, phosphorylation, and activation of Smad2.', answer the user's query.
What is the biomedical concept corresponding to 'tgfbeta type i receptor'?
[ "transforming growth factor beta receptor 1 (homo sapiens)", "tgfr-1 (homo sapiens)", "tgfbr1 (homo sapiens)", "tbetar-i (homo sapiens)" ]
[ "tgfbeta-rii (homo sapiens)", "transforming growth factor beta receptor i (xenopus tropicalis)", "transforming growth factor beta receptor 1 (bos taurus)", "tbrii (homo sapiens)" ]
Given the context 'Smad7 interacts stably with the activated TGFbeta type I receptor, thereby blocking the association, phosphorylation, and activation of Smad2.', answer the user's query.
What is the biomedical concept corresponding to 'smad2'?
[ "smad2 (homo sapiens)", "smad family member 2 (homo sapiens)", "hsmad2 (homo sapiens) (smad family member 2 (homo sapiens))", "madr2 (homo sapiens)", "madh2 (homo sapiens)" ]
[ "smad2 (mus musculus)", "smad family member 2 (mus musculus)", "smad-2 (mus musculus)", "smad2 (drosophila melanogaster)" ]
Given the context 'Smad7 interacts stably with the activated TGFbeta type I receptor, thereby blocking the association, phosphorylation, and activation of Smad2.', answer the user's query.
What is the biomedical concept corresponding to 'smad7'?
[ "smad family member 7 (homo sapiens)", "smad7 (homo sapiens)" ]
[ "smad family member 7 (mus musculus)", "smad7 (mus musculus)", "smad7 (drosophila melanogaster)", "smad family member 6 (homo sapiens)" ]
Given the context 'Furthermore, mutations in Smad7 that interfere with receptor binding disrupt its inhibitory activity.', answer the user's query.
What is the biomedical concept corresponding to 'sox22'?
[ "sox22 (homo sapiens)" ]
[ "sox2 (homo sapiens)", "sox25 (homo sapiens)", "transcription factor sox-2-like (homo sapiens)", "sox21 (homo sapiens)" ]
Given the context 'SOX22 is a new member of the SOX gene family, mainly expressed in human nervous tissue. ', answer the user's query.
What is the biomedical concept corresponding to 'sry'?
[ "sry (homo sapiens)", "sex determining region y (homo sapiens)" ]
[ "sry (drosophila melanogaster) (sprouty (drosophila melanogaster))", "sry (xenopus laevis) (sry-box 3 s homeolog (xenopus laevis))", "sex determining region y (sus scrofa)", "sex-determining region y protein (sus scrofa)" ]
Given the context 'SOX (SRY box-containing) genes share a particular DNA-binding domain, called HMG, with the mammalian testis-determining gene SRY Several SOX genes have already been shown to be transcription factors involved in the decision of important cell fates during development.', answer the user's query.
What is the biomedical concept corresponding to 'sox22'?
[ "sox22 (homo sapiens)" ]
[ "sox2 (homo sapiens)", "sox25 (homo sapiens)", "transcription factor sox-2-like (homo sapiens)", "sox21 (homo sapiens)" ]
Given the context 'Here we report the cloning of a new human member of the SOX gene family, SOX22.', answer the user's query.
What is the biomedical concept corresponding to 'sox22'?
[ "sox22 (homo sapiens)" ]
[ "sox2 (homo sapiens)", "sox25 (homo sapiens)", "transcription factor sox-2-like (homo sapiens)", "sox21 (homo sapiens)" ]
Given the context 'The SOX22 gene maps to chromosome 20 on band p13 and does not appear to be clustered with any other SOX gene mapped to date.', answer the user's query.
What is the biomedical concept corresponding to 'sox22'?
[ "sox22 (homo sapiens)" ]
[ "sox2 (homo sapiens)", "sox25 (homo sapiens)", "transcription factor sox-2-like (homo sapiens)", "sox21 (homo sapiens)" ]
Given the context 'SOX22 mRNA is expressed in various fetal and adult organs and tissues, suggesting that this gene plays roles in both differentiation and maintenance of several cell types.', answer the user's query.
What is the biomedical concept corresponding to 'retinal degeneration c'?
[ "retinal degeneration c (drosophila melanogaster)" ]
[ "retinal degeneration h (drosophila melanogaster)", "retinal degeneration d (drosophila melanogaster)", "retinal degeneration g (drosophila melanogaster)", "primary retinal dysplasia (homo sapiens)" ]
Given the context 'A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin. ', answer the user's query.
What is the biomedical concept corresponding to 'rdgc'?
[ "rdgc (drosophila melanogaster)" ]
[ "rdgb (homo sapiens)", "rdgca (homo sapiens)", "retinal pigment epithelium-derived rhodopsin homolog (xenopus tropicalis)", "retinal degeneration g (drosophila melanogaster)" ]
Given the context 'A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin. ', answer the user's query.
What is the biomedical concept corresponding to 'retinal degeneration c'?
[ "retinal degeneration c (drosophila melanogaster)" ]
[ "retinal degeneration h (drosophila melanogaster)", "retinal degeneration d (drosophila melanogaster)", "retinal degeneration g (drosophila melanogaster)", "primary retinal dysplasia (homo sapiens)" ]
Given the context 'Through our transcriptional mapping effort in the Xp22 region, we have isolated by exon trapping a new transcript highly homologous to the Drosophila retinal degeneration C (rdgC) gene.', answer the user's query.
What is the biomedical concept corresponding to 'rdgc'?
[ "rdgc (drosophila melanogaster)" ]
[ "rdgb (homo sapiens)", "rdgca (homo sapiens)", "retinal pigment epithelium-derived rhodopsin homolog (xenopus tropicalis)", "retinal degeneration g (drosophila melanogaster)" ]
Given the context 'Through our transcriptional mapping effort in the Xp22 region, we have isolated by exon trapping a new transcript highly homologous to the Drosophila retinal degeneration C (rdgC) gene.', answer the user's query.
What is the biomedical concept corresponding to 'rdgc'?
[ "rdgc (drosophila melanogaster)" ]
[ "rdgb (homo sapiens)", "rdgca (homo sapiens)", "retinal pigment epithelium-derived rhodopsin homolog (xenopus tropicalis)", "retinal degeneration g (drosophila melanogaster)" ]
Given the context 'rdgC encodes a serine/threonine phosphatase protein and is required in Drosophila to prevent light-induced retinal degeneration.', answer the user's query.
What is the biomedical concept corresponding to 'ppef'?
[ "ppef (homo sapiens)", "ppef1 (homo sapiens)" ]
[ "ppef2 (homo sapiens)", "epf (homo sapiens)", "ppef1 (xenopus tropicalis)", "pedf (homo sapiens)" ]
Given the context 'This human gene is the first mammalian member of the serine-threonine phosphatase with EF hand motif gene family, and was thus named PPEF (Protein Phosphatase with EF calcium-binding domain).', answer the user's query.
What is the biomedical concept corresponding to 'ppef'?
[ "ppef-1 (mus musculus)", "ppef1 (mus musculus)" ]
[ "ppef (homo sapiens)", "ppef1 (homo sapiens)", "ppef2 (homo sapiens)", "epf (homo sapiens)" ]
Given the context 'The expression pattern of the mouse Ppef gene was studied by RNA in situ hybridization on embryonic tissue sections.', answer the user's query.
What is the biomedical concept corresponding to 'rdgc'?
[ "rdgc (drosophila melanogaster)" ]
[ "rdgb (homo sapiens)", "rdgca (homo sapiens)", "retinal pigment epithelium-derived rhodopsin homolog (xenopus tropicalis)", "retinal degeneration g (drosophila melanogaster)" ]
Given the context 'While rdgC is expressed in the visual system of the fly, as well as in the mushroom bodies of the central brain, we found that Ppef is highly expressed in sensory neurons of the dorsal root ganglia (DRG) and neural crest-derived cranial ganglia.', answer the user's query.
What is the biomedical concept corresponding to 'ppef'?
[ "ppef-1 (mus musculus)", "ppef1 (mus musculus)" ]
[ "ppef (homo sapiens)", "ppef1 (homo sapiens)", "ppef2 (homo sapiens)", "epf (homo sapiens)" ]
Given the context 'While rdgC is expressed in the visual system of the fly, as well as in the mushroom bodies of the central brain, we found that Ppef is highly expressed in sensory neurons of the dorsal root ganglia (DRG) and neural crest-derived cranial ganglia.', answer the user's query.
What is the biomedical concept corresponding to 'ppef'?
[ "ppef (homo sapiens)", "ppef1 (homo sapiens)" ]
[ "ppef2 (homo sapiens)", "epf (homo sapiens)", "ppef1 (xenopus tropicalis)", "pedf (homo sapiens)" ]
Given the context 'The selective pattern of expression makes PPEF an important marker for sensory neuron differentiation and suggests a role for serine-threonine phosphatases in mammalian development.', answer the user's query.
What is the biomedical concept corresponding to 'hogg1'?
[ "hogg1 (homo sapiens)", "ogg1 (homo sapiens)", "8-oxoguanine dna glycosylase (homo sapiens)", "ogh1 (homo sapiens)" ]
[ "hoga1 (homo sapiens)", "hhg1 (homo sapiens)", "homg1 (homo sapiens)", "hspg1 (homo sapiens)" ]
Given the context 'Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae. ', answer the user's query.
What is the biomedical concept corresponding to 'fpg'?
[ "fpg (escherichia coli str. k-12 substr. mg1655)" ]
[ "fpg1 (homo sapiens)", "fpgs (homo sapiens)", "fpgt (homo sapiens)", "fpg2 (homo sapiens)" ]
Given the context 'The OGG1 gene of Saccharomyces cerevisiae encodes a DNA glycosylase activity that is a functional analog of the Fpg protein from Escherichia coli and excises 7,8-dihydro-8-oxoguanine (8-oxoG) from damaged DNA.', answer the user's query.
What is the biomedical concept corresponding to 'endonuclease iii'?
[ "endonuclease iii (escherichia coli str. k-12 substr. mg1655)" ]
[ "endonuclease iii homolog (caenorhabditis elegans)", "dna-(apurinic or apyrimidinic site) endonuclease;exodeoxyribonuclease iii (caenorhabditis elegans)", "endonuclease v (homo sapiens)", "endo-i (drosophila melanogaster) (uncharacterized protein (drosophila melanogaster))" ]
Given the context 'This protein shares a 38% sequence identity with the yeast Ogg1 protein, adding this novel human gene product to the growing family of enzymes that the repair of oxidatively damaged bases and are related to the E. coli endonuclease III.', answer the user's query.
What is the biomedical concept corresponding to 'fpg'?
[ "fpg (escherichia coli str. k-12 substr. mg1655)" ]
[ "fpg1 (homo sapiens)", "fpgs (homo sapiens)", "fpgt (homo sapiens)", "fpg2 (homo sapiens)" ]
Given the context 'The cloned coding sequence was expressed in an E. coli strain that carried a disrupted fpg gene, the bacterial functional analog of OGG1.', answer the user's query.
What is the biomedical concept corresponding to 'hogg1'?
[ "hogg1 (homo sapiens)", "ogg1 (homo sapiens)", "8-oxoguanine dna glycosylase (homo sapiens)", "ogh1 (homo sapiens)" ]
[ "hoga1 (homo sapiens)", "hhg1 (homo sapiens)", "homg1 (homo sapiens)", "hspg1 (homo sapiens)" ]
Given the context 'These results make this novel gene (hOGG1) a strong candidate for the human homolog of the yeast OGG1 and suggest an important role of its product in the protection of the genome from the mutagenic effects of the oxidatively damaged purines.', answer the user's query.
What is the biomedical concept corresponding to 'mink'?
[ "mink (homo sapiens) (potassium voltage-gated channel subfamily e regulatory subunit 1 (homo sapiens))" ]
[ "mink (drosophila melanogaster)", "mink1 (homo sapiens)", "mink (mus musculus) (potassium voltage-gated channel, isk-related subfamily, member 1 (mus musculus))", "min (mus musculus)" ]
Given the context 'A minK-HERG complex regulates the cardiac potassium current I(Kr). MinK is a widely expressed protein of relative molecular mass approximately 15K that forms potassium channels by aggregation with other membrane proteins.', answer the user's query.
What is the biomedical concept corresponding to 'herg'?
[ "herg (homo sapiens)", "herg1 (homo sapiens)" ]
[ "herg2 (homo sapiens)", "herg-2 (homo sapiens)", "kcnrg (homo sapiens)", "girk1 (homo sapiens)" ]
Given the context 'A minK-HERG complex regulates the cardiac potassium current I(Kr). MinK is a widely expressed protein of relative molecular mass approximately 15K that forms potassium channels by aggregation with other membrane proteins.', answer the user's query.
What is the biomedical concept corresponding to 'mink'?
[ "mink (homo sapiens) (potassium voltage-gated channel subfamily e regulatory subunit 1 (homo sapiens))" ]
[ "mink (drosophila melanogaster)", "mink1 (homo sapiens)", "mink (mus musculus) (potassium voltage-gated channel, isk-related subfamily, member 1 (mus musculus))", "min (mus musculus)" ]
Given the context 'A minK-HERG complex regulates the cardiac potassium current I(Kr). MinK is a widely expressed protein of relative molecular mass approximately 15K that forms potassium channels by aggregation with other membrane proteins.', answer the user's query.
What is the biomedical concept corresponding to 'mink'?
[ "mink (homo sapiens) (potassium voltage-gated channel subfamily e regulatory subunit 1 (homo sapiens))" ]
[ "mink (drosophila melanogaster)", "mink1 (homo sapiens)", "mink (mus musculus) (potassium voltage-gated channel, isk-related subfamily, member 1 (mus musculus))", "min (mus musculus)" ]
Given the context 'MinK governs ion channel activation, regulation by second messengers, and the function and structure of the ion conduction pathway.', answer the user's query.
What is the biomedical concept corresponding to 'mink'?
[ "mink (homo sapiens) (potassium voltage-gated channel subfamily e regulatory subunit 1 (homo sapiens))" ]
[ "mink (drosophila melanogaster)", "mink1 (homo sapiens)", "mink (mus musculus) (potassium voltage-gated channel, isk-related subfamily, member 1 (mus musculus))", "min (mus musculus)" ]
Given the context 'Association of minK with a channel protein known as KvLQT1 produces a voltage-gated outward K+ current (I[sK]) resembling the slow cardiac repolarization current (I[Ks]).', answer the user's query.
What is the biomedical concept corresponding to 'kvlqt1'?
[ "kvlqt1 (homo sapiens)" ]
[ "kvlqt1 (xenopus laevis) (potassium channel, voltage gated kqt-like subfamily q, member 1 l homeolog (xenopus laevis))", "kvlqt1 (mus musculus)", "kvlqt1 (rattus norvegicus)", "potassium voltage-gated channel subfamily kqt member 1 (xenopus tropicalis)" ]
Given the context 'Association of minK with a channel protein known as KvLQT1 produces a voltage-gated outward K+ current (I[sK]) resembling the slow cardiac repolarization current (I[Ks]).', answer the user's query.
What is the biomedical concept corresponding to 'herg'?
[ "herg (homo sapiens)", "herg1 (homo sapiens)" ]
[ "herg2 (homo sapiens)", "herg-2 (homo sapiens)", "kcnrg (homo sapiens)", "girk1 (homo sapiens)" ]
Given the context 'HERG, a human homologue of the ether-a-go-go gene of the fruitfly Drosophila melanogaster, encodes a protein that produces the rapidly activating cardiac delayed rectifier (I[Kr]).', answer the user's query.
What is the biomedical concept corresponding to 'ether-a-go-go'?
[ "ether a go-go (drosophila melanogaster)" ]
[ "gone early (drosophila melanogaster)", "gogo (drosophila melanogaster)", "goe (drosophila melanogaster)", "go-alpha (drosophila melanogaster)" ]
Given the context 'HERG, a human homologue of the ether-a-go-go gene of the fruitfly Drosophila melanogaster, encodes a protein that produces the rapidly activating cardiac delayed rectifier (I[Kr]).', answer the user's query.
What is the biomedical concept corresponding to 'herg'?
[ "herg (homo sapiens)", "herg1 (homo sapiens)" ]
[ "herg2 (homo sapiens)", "herg-2 (homo sapiens)", "kcnrg (homo sapiens)", "girk1 (homo sapiens)" ]
Given the context 'Although heterologously expressed HERG channels are largely indistinguishable from native cardiac I(Kr), a role for minK in this current is suggested by the diminished I(Kr) in an atrial tumour line subjected to minK antisense suppression.', answer the user's query.
What is the biomedical concept corresponding to 'mink'?
[ "mink (homo sapiens) (potassium voltage-gated channel subfamily e regulatory subunit 1 (homo sapiens))" ]
[ "mink (drosophila melanogaster)", "mink1 (homo sapiens)", "mink (mus musculus) (potassium voltage-gated channel, isk-related subfamily, member 1 (mus musculus))", "min (mus musculus)" ]
Given the context 'Although heterologously expressed HERG channels are largely indistinguishable from native cardiac I(Kr), a role for minK in this current is suggested by the diminished I(Kr) in an atrial tumour line subjected to minK antisense suppression.', answer the user's query.
What is the biomedical concept corresponding to 'mink'?
[ "mink (homo sapiens) (potassium voltage-gated channel subfamily e regulatory subunit 1 (homo sapiens))" ]
[ "mink (drosophila melanogaster)", "mink1 (homo sapiens)", "mink (mus musculus) (potassium voltage-gated channel, isk-related subfamily, member 1 (mus musculus))", "min (mus musculus)" ]
Given the context 'Although heterologously expressed HERG channels are largely indistinguishable from native cardiac I(Kr), a role for minK in this current is suggested by the diminished I(Kr) in an atrial tumour line subjected to minK antisense suppression.', answer the user's query.
What is the biomedical concept corresponding to 'herg'?
[ "herg (homo sapiens)", "herg1 (homo sapiens)" ]
[ "herg2 (homo sapiens)", "herg-2 (homo sapiens)", "kcnrg (homo sapiens)", "girk1 (homo sapiens)" ]
Given the context 'Here we show that HERG and minK form a stable complex, and that this heteromultimerization regulates I(Kr) activity.', answer the user's query.
What is the biomedical concept corresponding to 'mink'?
[ "mink (homo sapiens) (potassium voltage-gated channel subfamily e regulatory subunit 1 (homo sapiens))" ]
[ "mink (drosophila melanogaster)", "mink1 (homo sapiens)", "mink (mus musculus) (potassium voltage-gated channel, isk-related subfamily, member 1 (mus musculus))", "min (mus musculus)" ]
Given the context 'Here we show that HERG and minK form a stable complex, and that this heteromultimerization regulates I(Kr) activity.', answer the user's query.
What is the biomedical concept corresponding to 'mink'?
[ "mink (homo sapiens) (potassium voltage-gated channel subfamily e regulatory subunit 1 (homo sapiens))" ]
[ "mink (drosophila melanogaster)", "mink1 (homo sapiens)", "mink (mus musculus) (potassium voltage-gated channel, isk-related subfamily, member 1 (mus musculus))", "min (mus musculus)" ]
Given the context 'MinK, through the formation of heteromeric channel complexes, is thus central to the control of the heart rate and rhythm.', answer the user's query.
What is the biomedical concept corresponding to 'x-linked iap'?
[ "x-linked inhibitor of apoptosis (homo sapiens)" ]
[ "c-iap1 (xenopus laevis) (baculoviral iap repeat containing 2 s homeolog (xenopus laevis))", "c-iap1 (xenopus laevis) (baculoviral iap repeat containing 2 l homeolog (xenopus laevis))", "iap-1 (homo sapiens)", "baculoviral iap repeat-containing protein 1-like (xenopus laevis)" ]
Given the context 'X-linked IAP is a direct inhibitor of cell-death proteases. ', answer the user's query.
What is the biomedical concept corresponding to 'x-chromosome-linked iap'?
[ "x-linked inhibitor of apoptosis (homo sapiens)" ]
[ "c-iap1 (xenopus laevis) (baculoviral iap repeat containing 2 s homeolog (xenopus laevis))", "c-iap1 (xenopus laevis) (baculoviral iap repeat containing 2 l homeolog (xenopus laevis))", "baculoviral iap repeat-containing protein 1-like (xenopus laevis)", "c-iap1 (xenopus tropicalis)" ]
Given the context 'Here we show that human X-chromosome-linked IAP directly inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.', answer the user's query.
What is the biomedical concept corresponding to 'caspase-3'?
[ "casp3 (homo sapiens)", "caspase 3 (homo sapiens)" ]
[ "caspase 3 (drosophila melanogaster) (death related ice-like caspase (drosophila melanogaster))", "ich-3 (homo sapiens)", "ice-lap3 (homo sapiens)", "caspase-3 (mus musculus)" ]
Given the context 'Here we show that human X-chromosome-linked IAP directly inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.', answer the user's query.
What is the biomedical concept corresponding to 'caspase-7'?
[ "casp-7 (homo sapiens)", "casp7 (homo sapiens)", "caspase 7 (homo sapiens)" ]
[ "casp-8 (homo sapiens)", "caspase-7 (mus musculus)", "casp8 (homo sapiens)", "casp5 (homo sapiens)" ]
Given the context 'Here we show that human X-chromosome-linked IAP directly inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.', answer the user's query.
What is the biomedical concept corresponding to 'fxr1'?
[ "fxr1 (homo sapiens)" ]
[ "fxr (homo sapiens)", "fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis))", "fxr1 (xenopus tropicalis)", "fxr1 (xenopus laevis)" ]
Given the context 'Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis. ', answer the user's query.
What is the biomedical concept corresponding to 'fxr2'?
[ "fxr2 (homo sapiens)", "fmr1 autosomal homolog 2 (homo sapiens)" ]
[ "fxr (homo sapiens)", "fxrb (homo sapiens)", "fxr1 (homo sapiens)", "nr1f2 (homo sapiens)" ]
Given the context 'Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis. ', answer the user's query.
What is the biomedical concept corresponding to 'fragile x mental retardation protein'?
[ "fmr1 (homo sapiens) (fragile x messenger ribonucleoprotein 1 (homo sapiens))", "fmrp (homo sapiens)", "fragile x messenger ribonucleoprotein 1 (homo sapiens)", "fraxa (homo sapiens) (fragile x messenger ribonucleoprotein 1 (homo sapiens))" ]
[ "fmr1 (homo sapiens) (fragile site, folic acid type, rare, fra(x)(q27.3) a (homo sapiens))", "fxr (drosophila melanogaster) (fragile x messenger ribonucleoprotein 1 (drosophila melanogaster))", "fraxf (homo sapiens)", "fmr1 autosomal homolog 1 (homo sapiens)" ]
Given the context 'Lack of expression of the fragile X mental retardation protein (FMRP) results in mental retardation and macroorchidism, seen as the major pathological symptoms in fragile X patients.', answer the user's query.
What is the biomedical concept corresponding to 'fmrp'?
[ "fmrp (homo sapiens)", "fmr1 (homo sapiens) (fragile x messenger ribonucleoprotein 1 (homo sapiens))" ]
[ "fmrp (drosophila melanogaster)", "fmrp (mus musculus)", "fxr (drosophila melanogaster) (fragile x messenger ribonucleoprotein 1 (drosophila melanogaster))", "fragile x messenger ribonucleoprotein 1 (drosophila melanogaster)" ]
Given the context 'Lack of expression of the fragile X mental retardation protein (FMRP) results in mental retardation and macroorchidism, seen as the major pathological symptoms in fragile X patients.', answer the user's query.
What is the biomedical concept corresponding to 'fmrp'?
[ "fmrp (homo sapiens)", "fmr1 (homo sapiens) (fragile x messenger ribonucleoprotein 1 (homo sapiens))" ]
[ "fmrp (drosophila melanogaster)", "fmrp (mus musculus)", "fxr (drosophila melanogaster) (fragile x messenger ribonucleoprotein 1 (drosophila melanogaster))", "fragile x messenger ribonucleoprotein 1 (drosophila melanogaster)" ]
Given the context 'FMRP is a cytoplasmic RNA-binding protein which cosediments with the 60S ribosomal subunit.', answer the user's query.
What is the biomedical concept corresponding to 'fmrp'?
[ "fmrp (homo sapiens)", "fmr1 (homo sapiens) (fragile x messenger ribonucleoprotein 1 (homo sapiens))" ]
[ "fmrp (drosophila melanogaster)", "fmrp (mus musculus)", "fxr (drosophila melanogaster) (fragile x messenger ribonucleoprotein 1 (drosophila melanogaster))", "fragile x messenger ribonucleoprotein 1 (drosophila melanogaster)" ]
Given the context 'Recently, two proteins homologous to FMRP were discovered: FXR1 and FXR2.', answer the user's query.
What is the biomedical concept corresponding to 'fxr1'?
[ "fxr1 (homo sapiens)" ]
[ "fxr (homo sapiens)", "fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis))", "fxr1 (xenopus tropicalis)", "fxr1 (xenopus laevis)" ]
Given the context 'Recently, two proteins homologous to FMRP were discovered: FXR1 and FXR2.', answer the user's query.
What is the biomedical concept corresponding to 'fxr2'?
[ "fxr2 (homo sapiens)", "fmr1 autosomal homolog 2 (homo sapiens)" ]
[ "fxr (homo sapiens)", "fxrb (homo sapiens)", "fxr1 (homo sapiens)", "nr1f2 (homo sapiens)" ]
Given the context 'Recently, two proteins homologous to FMRP were discovered: FXR1 and FXR2.', answer the user's query.
What is the biomedical concept corresponding to 'fmrp'?
[ "fmrp (homo sapiens)", "fmr1 (homo sapiens) (fragile x messenger ribonucleoprotein 1 (homo sapiens))" ]
[ "fmrp (drosophila melanogaster)", "fmrp (mus musculus)", "fxr (drosophila melanogaster) (fragile x messenger ribonucleoprotein 1 (drosophila melanogaster))", "fragile x messenger ribonucleoprotein 1 (drosophila melanogaster)" ]
Given the context 'These novel proteins interact with FMRP and with each other and they are also associated with the 60S ribosomal subunit.', answer the user's query.
What is the biomedical concept corresponding to 'fxr1'?
[ "fxr1 (homo sapiens)" ]
[ "fxr (homo sapiens)", "fxr1-a (xenopus laevis) (fmr1 autosomal homolog 1 s homeolog (xenopus laevis))", "fxr1 (xenopus tropicalis)", "fxr1 (xenopus laevis)" ]
Given the context 'In adult brain, FMR1, FXR1 and FXR2 proteins are coexpressed in the cytoplasm of specific differentiated neurons only.', answer the user's query.
What is the biomedical concept corresponding to 'fxr2'?
[ "fxr2 (homo sapiens)", "fmr1 autosomal homolog 2 (homo sapiens)" ]
[ "fxr (homo sapiens)", "fxrb (homo sapiens)", "fxr1 (homo sapiens)", "nr1f2 (homo sapiens)" ]
Given the context 'In adult brain, FMR1, FXR1 and FXR2 proteins are coexpressed in the cytoplasm of specific differentiated neurons only.', answer the user's query.
What is the biomedical concept corresponding to 'phog'?
[ "phog1 (homo sapiens)" ]
[ "phop (escherichia coli str. k-12 substr. mg1655)", "pp2cg (homo sapiens)", "phoh (escherichia coli str. k-12 substr. mg1655)", "phosphoglycolate phosphatase (homo sapiens)" ]
Given the context 'PHOG, a candidate gene for involvement in the short stature of Turner syndrome. ', answer the user's query.
What is the biomedical concept corresponding to 'phog'?
[ "phog1 (homo sapiens)" ]
[ "phop (escherichia coli str. k-12 substr. mg1655)", "pp2cg (homo sapiens)", "phoh (escherichia coli str. k-12 substr. mg1655)", "phosphoglycolate phosphatase (homo sapiens)" ]
Given the context 'We have named the gene PHOG, for pseudoautosomal homeobox-containing osteogenic gene.', answer the user's query.
What is the biomedical concept corresponding to 'pseudoautosomal homeobox-containing osteogenic gene'?
[ "shox homeobox (homo sapiens)", "shox (homo sapiens)", "shoxy (homo sapiens)" ]
[ "shox homeobox s homeolog (xenopus laevis)", "provisional ortholog of chitinase acidic s homeolog (xenopus laevis)", "sulfite oxidase pseudogene (homo sapiens)", "ooep-as (homo sapiens)" ]
Given the context 'We have named the gene PHOG, for pseudoautosomal homeobox-containing osteogenic gene.', answer the user's query.
What is the biomedical concept corresponding to 'phog'?
[ "phog1 (homo sapiens)" ]
[ "phop (escherichia coli str. k-12 substr. mg1655)", "pp2cg (homo sapiens)", "phoh (escherichia coli str. k-12 substr. mg1655)", "phosphoglycolate phosphatase (homo sapiens)" ]
Given the context 'Its deletion in patients with short stature, the predicted altered dosage in 45,X individuals, along with the nature of the encoded protein and its expression pattern, make PHOG an attractive candidate for involvement in the short stature of Turner syndrome.', answer the user's query.
What is the biomedical concept corresponding to 'phog'?
[ "phog1 (homo sapiens)" ]
[ "phop (escherichia coli str. k-12 substr. mg1655)", "pp2cg (homo sapiens)", "phoh (escherichia coli str. k-12 substr. mg1655)", "phosphoglycolate phosphatase (homo sapiens)" ]
Given the context 'We have also found that the mouse homolog of PHOG is autosomal, which may help to explain the lack of a growth abnormality in mice with monosomy X.', answer the user's query.
What is the biomedical concept corresponding to 'stat4'?
[ "stat4 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
[ "stati4 (homo sapiens)", "il-4-statb (homo sapiens)", "signal transducer and activator of transcription 4 (xenopus tropicalis)", "cis4 (homo sapiens)" ]
Given the context 'cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3. ', answer the user's query.
What is the biomedical concept corresponding to 'stat4'?
[ "stat4 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
[ "stati4 (homo sapiens)", "il-4-statb (homo sapiens)", "signal transducer and activator of transcription 4 (xenopus tropicalis)", "cis4 (homo sapiens)" ]
Given the context 'cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3. ', answer the user's query.
What is the biomedical concept corresponding to 'stat1'?
[ "stat1 (homo sapiens)", "signal transducer and activator of transcription 1 (homo sapiens)", "isgf-3 (homo sapiens) (signal transducer and activator of transcription 1 (homo sapiens))", "stat91 (homo sapiens)" ]
[ "signal transducer and activator of transcription 1 (xenopus tropicalis)", "stat3 (homo sapiens)", "signal transducer and activator of transcription 2 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
Given the context 'cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3. ', answer the user's query.
What is the biomedical concept corresponding to 'stat4'?
[ "stat4 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
[ "stati4 (homo sapiens)", "il-4-statb (homo sapiens)", "signal transducer and activator of transcription 4 (xenopus tropicalis)", "cis4 (homo sapiens)" ]
Given the context 'STAT4 is phosphorylated following interleukin (IL)-12 stimulation and is essential for IL-12 signal transduction.', answer the user's query.
What is the biomedical concept corresponding to 'stat4'?
[ "stat4 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
[ "stati4 (homo sapiens)", "il-4-statb (homo sapiens)", "signal transducer and activator of transcription 4 (xenopus tropicalis)", "cis4 (homo sapiens)" ]
Given the context 'The human STAT4 cDNA was cloned, and both STAT4 and STAT1 genes were mapped to human chromosome bands 2q32.2-->q32.3 by fluorescence in situ hybridization.', answer the user's query.
What is the biomedical concept corresponding to 'stat4'?
[ "stat4 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
[ "stati4 (homo sapiens)", "il-4-statb (homo sapiens)", "signal transducer and activator of transcription 4 (xenopus tropicalis)", "cis4 (homo sapiens)" ]
Given the context 'The human STAT4 cDNA was cloned, and both STAT4 and STAT1 genes were mapped to human chromosome bands 2q32.2-->q32.3 by fluorescence in situ hybridization.', answer the user's query.
What is the biomedical concept corresponding to 'stat1'?
[ "stat1 (homo sapiens)", "signal transducer and activator of transcription 1 (homo sapiens)", "isgf-3 (homo sapiens) (signal transducer and activator of transcription 1 (homo sapiens))", "stat91 (homo sapiens)" ]
[ "signal transducer and activator of transcription 1 (xenopus tropicalis)", "stat3 (homo sapiens)", "signal transducer and activator of transcription 2 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
Given the context 'The human STAT4 cDNA was cloned, and both STAT4 and STAT1 genes were mapped to human chromosome bands 2q32.2-->q32.3 by fluorescence in situ hybridization.', answer the user's query.
What is the biomedical concept corresponding to 'stat4'?
[ "stat4 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
[ "stati4 (homo sapiens)", "il-4-statb (homo sapiens)", "signal transducer and activator of transcription 4 (xenopus tropicalis)", "cis4 (homo sapiens)" ]
Given the context 'These results suggest that STAT4 and STAT1 may have arisen via a tandem gene duplication.', answer the user's query.
What is the biomedical concept corresponding to 'stat1'?
[ "stat1 (homo sapiens)", "signal transducer and activator of transcription 1 (homo sapiens)", "isgf-3 (homo sapiens) (signal transducer and activator of transcription 1 (homo sapiens))", "stat91 (homo sapiens)" ]
[ "signal transducer and activator of transcription 1 (xenopus tropicalis)", "stat3 (homo sapiens)", "signal transducer and activator of transcription 2 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
Given the context 'These results suggest that STAT4 and STAT1 may have arisen via a tandem gene duplication.', answer the user's query.
What is the biomedical concept corresponding to 'stat1'?
[ "stat1 (homo sapiens)", "signal transducer and activator of transcription 1 (homo sapiens)", "isgf-3 (homo sapiens) (signal transducer and activator of transcription 1 (homo sapiens))", "stat91 (homo sapiens)" ]
[ "signal transducer and activator of transcription 1 (xenopus tropicalis)", "stat3 (homo sapiens)", "signal transducer and activator of transcription 2 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
Given the context 'However, human STAT1 is expressed ubiquitously, whereas human STAT4 is expressed in several tissues including spleen, heart, brain, peripheral blood cells, and testis.', answer the user's query.
What is the biomedical concept corresponding to 'stat4'?
[ "stat4 (homo sapiens)", "signal transducer and activator of transcription 4 (homo sapiens)" ]
[ "stati4 (homo sapiens)", "il-4-statb (homo sapiens)", "signal transducer and activator of transcription 4 (xenopus tropicalis)", "cis4 (homo sapiens)" ]
Given the context 'However, human STAT1 is expressed ubiquitously, whereas human STAT4 is expressed in several tissues including spleen, heart, brain, peripheral blood cells, and testis.', answer the user's query.
What is the biomedical concept corresponding to 'rab7l1'?
[ "rab7l1 (homo sapiens)", "rab7l (homo sapiens)" ]
[ "rab7l1 (drosophila melanogaster)", "rab7l (drosophila melanogaster)", "rab7 (xenopus laevis) (rab7a, member ras oncogene family l homeolog (xenopus laevis))", "rab7l1 (bos taurus)" ]
Given the context 'Cloning and chromosome assignment to 1q32 of a human cDNA (RAB7L1) encoding a small GTP-binding protein, a member of the RAS superfamily. ', answer the user's query.
What is the biomedical concept corresponding to 'rab7'?
[ "rab7 (homo sapiens) (rab7a, member ras oncogene family (homo sapiens))", "rab7a (homo sapiens)", "rab7a, member ras oncogene family (homo sapiens)" ]
[ "rab7 (homo sapiens) (rab7b, member ras oncogene family (homo sapiens))", "rab7b, member ras oncogene family (homo sapiens)", "rab-7 (drosophila melanogaster)", "rab7b (homo sapiens)" ]
Given the context 'A full-length cDNA homologous to RAB7, a member of the RAB-related GTP-binding protein subfamily, was isolated from a human placenta cDNA library.', answer the user's query.
What is the biomedical concept corresponding to 'rab7l1'?
[ "rab7l1 (homo sapiens)", "rab7l (homo sapiens)" ]
[ "rab7l1 (drosophila melanogaster)", "rab7l (drosophila melanogaster)", "rab7 (xenopus laevis) (rab7a, member ras oncogene family l homeolog (xenopus laevis))", "rab7l1 (bos taurus)" ]
Given the context 'This cDNA, designated RAB7L1, has an open reading frame of 609 nucleotides encoding 203 amino acids.', answer the user's query.
What is the biomedical concept corresponding to 'beta-arrestin2'?
[ "arrestin beta 2 (homo sapiens)", "arb2 (homo sapiens) (arrestin beta 2 (homo sapiens))", "arrb2 (homo sapiens)", "arr2 (homo sapiens)" ]
[ "arr (drosophila melanogaster) (arrestin 2 (drosophila melanogaster))", "arrestin 2 (drosophila melanogaster)", "arrestin beta 1 (homo sapiens)", "arrestin beta 2 (bos taurus)" ]
Given the context 'In this work we provide a novel approach to this problem using a beta-arrestin2/green fluorescent protein conjugate (betaarr2-GFP).', answer the user's query.
What is the biomedical concept corresponding to 'betaarr2'?
[ "arrestin beta 2 (homo sapiens)", "arb2 (homo sapiens) (arrestin beta 2 (homo sapiens))", "arrb2 (homo sapiens)", "arr2 (homo sapiens)" ]
[ "arb2 (homo sapiens) (adrenoceptor beta 2 (homo sapiens))", "betaarr2 (xenopus tropicalis)", "grin2b (homo sapiens)", "arrb2 (rattus norvegicus) (arrestin, beta 2, pseudogene (rattus norvegicus))" ]
Given the context 'In this work we provide a novel approach to this problem using a beta-arrestin2/green fluorescent protein conjugate (betaarr2-GFP).', answer the user's query.
What is the biomedical concept corresponding to 'betaarr2'?
[ "arrestin beta 2 (homo sapiens)", "arb2 (homo sapiens) (arrestin beta 2 (homo sapiens))", "arrb2 (homo sapiens)", "arr2 (homo sapiens)" ]
[ "arb2 (homo sapiens) (adrenoceptor beta 2 (homo sapiens))", "betaarr2 (xenopus tropicalis)", "grin2b (homo sapiens)", "arrb2 (rattus norvegicus) (arrestin, beta 2, pseudogene (rattus norvegicus))" ]
Given the context 'Confocal microscopy demonstrates the translocation of betaarr2-GFP to more than 15 different ligand-activated GPCRs.', answer the user's query.
What is the biomedical concept corresponding to 'betaarr2'?
[ "arrestin beta 2 (homo sapiens)", "arb2 (homo sapiens) (arrestin beta 2 (homo sapiens))", "arrb2 (homo sapiens)", "arr2 (homo sapiens)" ]
[ "arb2 (homo sapiens) (adrenoceptor beta 2 (homo sapiens))", "betaarr2 (xenopus tropicalis)", "grin2b (homo sapiens)", "arrb2 (rattus norvegicus) (arrestin, beta 2, pseudogene (rattus norvegicus))" ]
Given the context 'The use of betaarr2-GFP as a biosensor to recognize the activation of pharmacologically distinct GPCRs should accelerate the identification of orphan receptors and permit the optical study of their signal transduction biology intractable to ordinary biochemical methods.', answer the user's query.
What is the biomedical concept corresponding to 'hepatocyte growth factor activator inhibitor type 2'?
[ "serine peptidase inhibitor, kunitz type 2 (homo sapiens)", "hai2 (homo sapiens)", "hai-2 (homo sapiens)" ]
[ "pai2 (homo sapiens)", "pai-2 (homo sapiens)", "serpin family i member 2 (homo sapiens)", "serpina2 (homo sapiens)" ]
Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor. Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', answer the user's query.
What is the biomedical concept corresponding to 'hepatocyte growth factor (hgf) activator'?
[ "hgf activator (homo sapiens)", "hgfa (homo sapiens)", "hgfac (homo sapiens)" ]
[ "hepatocyte growth factor activator (mus musculus)", "hepatocyte growth factor (homo sapiens)", "hgf (homo sapiens) (hepatocyte growth factor (homo sapiens))", "hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens))" ]
Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor. Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', answer the user's query.
What is the biomedical concept corresponding to 'hgf'?
[ "hepatocyte growth factor (homo sapiens)", "hgf (homo sapiens) (hepatocyte growth factor (homo sapiens))", "sf (homo sapiens) (hepatocyte growth factor (homo sapiens))" ]
[ "hgfa (homo sapiens)", "hgf (homo sapiens) (interleukin 6 (homo sapiens))", "hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens))", "hgf activator (homo sapiens)" ]
Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor. Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', answer the user's query.
What is the biomedical concept corresponding to 'hgf'?
[ "hepatocyte growth factor (homo sapiens)", "hgf (homo sapiens) (hepatocyte growth factor (homo sapiens))", "sf (homo sapiens) (hepatocyte growth factor (homo sapiens))" ]
[ "hgfa (homo sapiens)", "hgf (homo sapiens) (interleukin 6 (homo sapiens))", "hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens))", "hgf activator (homo sapiens)" ]
Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor. Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', answer the user's query.
What is the biomedical concept corresponding to 'hgf activator'?
[ "hgf activator (homo sapiens)", "hgfa (homo sapiens)", "hgfac (homo sapiens)" ]
[ "hepatocyte growth factor activator (mus musculus)", "hgf (homo sapiens) (hepatocyte growth factor (homo sapiens))", "hepatocyte growth factor (homo sapiens)", "hgfal (homo sapiens)" ]
Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', answer the user's query.
What is the biomedical concept corresponding to 'hgf activator inhibitor type 1'?
[ "serine peptidase inhibitor, kunitz type 1 (homo sapiens)", "hai1 (homo sapiens)", "hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens))" ]
[ "agti (homo sapiens)", "antizyme inhibitor 1 (homo sapiens)", "hypoxia inducible factor 1 subunit alpha inhibitor (homo sapiens)", "pai1 (homo sapiens)" ]
Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', answer the user's query.
What is the biomedical concept corresponding to 'hai-1'?
[ "hai1 (homo sapiens)", "hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens))" ]
[ "hait1 (homo sapiens)", "haip1 (homo sapiens)", "hai-2 (homo sapiens)", "hai2 (homo sapiens)" ]
Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', answer the user's query.
What is the biomedical concept corresponding to 'hai-1'?
[ "hai1 (homo sapiens)", "hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens))" ]
[ "hait1 (homo sapiens)", "haip1 (homo sapiens)", "hai-2 (homo sapiens)", "hai2 (homo sapiens)" ]
Given the context 'HAI-1 is a novel member of the Kunitz family of serine protease inhibitors.', answer the user's query.
What is the biomedical concept corresponding to 'hgf activator'?
[ "hgf activator (homo sapiens)", "hgfa (homo sapiens)", "hgfac (homo sapiens)" ]
[ "hepatocyte growth factor activator (mus musculus)", "hgf (homo sapiens) (hepatocyte growth factor (homo sapiens))", "hepatocyte growth factor (homo sapiens)", "hgfal (homo sapiens)" ]
Given the context 'In the present study, we purified a second type of HGF activator inhibitor (HAI-2) from the conditioned medium of MKN45 cells and molecularly cloned its cDNA.', answer the user's query.
What is the biomedical concept corresponding to 'hai-2'?
[ "hai-2 (homo sapiens)", "hai2 (homo sapiens)", "serine peptidase inhibitor, kunitz type 2 (homo sapiens)" ]
[ "itih2 (homo sapiens)", "hcinf2 (homo sapiens)", "inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens)", "iti-hc2 (homo sapiens)" ]
Given the context 'In the present study, we purified a second type of HGF activator inhibitor (HAI-2) from the conditioned medium of MKN45 cells and molecularly cloned its cDNA.', answer the user's query.
What is the biomedical concept corresponding to 'hai-2'?
[ "hai-2 (homo sapiens)", "hai2 (homo sapiens)", "serine peptidase inhibitor, kunitz type 2 (homo sapiens)" ]
[ "itih2 (homo sapiens)", "hcinf2 (homo sapiens)", "inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens)", "iti-hc2 (homo sapiens)" ]
Given the context 'The cDNA sequence revealed that HAI-2 is derived from a precursor protein of 252 amino acids and contains two Kunitz domains, indicating that HAI-2 is also a member of the Kunitz family of serine protease inhibitors.', answer the user's query.
What is the biomedical concept corresponding to 'hai-2'?
[ "hai-2 (homo sapiens)", "hai2 (homo sapiens)", "serine peptidase inhibitor, kunitz type 2 (homo sapiens)" ]
[ "itih2 (homo sapiens)", "hcinf2 (homo sapiens)", "inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens)", "iti-hc2 (homo sapiens)" ]
Given the context 'The cDNA sequence revealed that HAI-2 is derived from a precursor protein of 252 amino acids and contains two Kunitz domains, indicating that HAI-2 is also a member of the Kunitz family of serine protease inhibitors.', answer the user's query.