query string | positive list | negative list | system string |
|---|---|---|---|
What is the biomedical concept corresponding to 'monokine induced by ifn-gamma'? | [
"mig (homo sapiens)"
] | [
"mip2g (homo sapiens)",
"mip-1d (homo sapiens)",
"mip-2g (homo sapiens)",
"mig-6 (homo sapiens)"
] | Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC chemokine receptor 3 (CXCR3), which is known to be expressed predominately on memory and activated T lymphocytes, is a receptor for both interferon gamma (IFN-gamma)-inducible protein 10 (gamma IP-10) and monokine induced by IFN-gamma (Mig).', answer the user's query. |
What is the biomedical concept corresponding to 'mig'? | [
"mig (homo sapiens)"
] | [
"mig-6 (homo sapiens)",
"mig1 (homo sapiens)",
"mig10 (homo sapiens)",
"mig9 (homo sapiens)"
] | Given the context 'CXC chemokine receptor 3 expression on CD34(+) hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon gamma-inducible protein 10 and monokine induced by interferon gamma.
CXC chemokine receptor 3 (CXCR3), which is known to be expressed predominately on memory and activated T lymphocytes, is a receptor for both interferon gamma (IFN-gamma)-inducible protein 10 (gamma IP-10) and monokine induced by IFN-gamma (Mig).', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr3'? | [
"cxcr3 (homo sapiens)",
"c-x-c motif chemokine receptor 3 (homo sapiens)"
] | [
"cc-ckr-3 (homo sapiens)",
"c-x3-c motif chemokine receptor 1 (homo sapiens)",
"cc-ckr-9 (homo sapiens)",
"c-c motif chemokine receptor 3 (homo sapiens)"
] | Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'granulocyte-macrophage colony-stimulating factor'? | [
"colony stimulating factor 2 (homo sapiens)",
"gmcsf (homo sapiens)",
"csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))",
"csf2 (homo sapiens)"
] | [
"colony stimulating factor 1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)",
"csf-1 (homo sapiens)",
"myeloid derived growth factor (homo sapiens)"
] | Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'gm-csf'? | [
"colony stimulating factor 2 (homo sapiens)",
"gmcsf (homo sapiens)",
"csf2 (homo sapiens)",
"csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)",
"csf-1 (homo sapiens)",
"multi-csf (homo sapiens)"
] | Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'We report the novel finding that CXCR3 is also expressed on CD34(+) hematopoietic progenitors from human cord blood stimulated with granulocyte-macrophage colony-stimulating factor (GM-CSF) but not on freshly isolated CD34(+) progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr3'? | [
"cxcr3 (homo sapiens)",
"c-x-c motif chemokine receptor 3 (homo sapiens)"
] | [
"cc-ckr-3 (homo sapiens)",
"c-x3-c motif chemokine receptor 1 (homo sapiens)",
"cc-ckr-9 (homo sapiens)",
"c-c motif chemokine receptor 3 (homo sapiens)"
] | Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', answer the user's query. |
What is the biomedical concept corresponding to 'gm-csf'? | [
"colony stimulating factor 2 (homo sapiens)",
"gmcsf (homo sapiens)",
"csf2 (homo sapiens)",
"csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)",
"csf-1 (homo sapiens)",
"multi-csf (homo sapiens)"
] | Given the context 'Freshly isolated CD34(+) progenitors expressed low levels of CXCR3 messenger RNA, but this expression was highly up-regulated by GM-CSF, as indicated by a real-time quantitative reverse transcriptase-polymerase chain reaction technique.', answer the user's query. |
What is the biomedical concept corresponding to 'gamma ip-10'? | [
"ip-10 (homo sapiens)",
"c-x-c motif chemokine ligand 10 (homo sapiens)",
"gip-10 (homo sapiens)",
"ifi10 (homo sapiens)"
] | [
"interleukin 1 family member 10 (homo sapiens)",
"interleukin 10 (homo sapiens)",
"il-10c (homo sapiens)",
"interferon alpha 10 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', answer the user's query. |
What is the biomedical concept corresponding to 'mig'? | [
"mig (homo sapiens)"
] | [
"mig-6 (homo sapiens)",
"mig1 (homo sapiens)",
"mig10 (homo sapiens)",
"mig9 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', answer the user's query. |
What is the biomedical concept corresponding to 'gm-csf'? | [
"colony stimulating factor 2 (homo sapiens)",
"gmcsf (homo sapiens)",
"csf2 (homo sapiens)",
"csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)",
"csf-1 (homo sapiens)",
"multi-csf (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr3'? | [
"cxcr3 (homo sapiens)",
"c-x-c motif chemokine receptor 3 (homo sapiens)"
] | [
"cc-ckr-3 (homo sapiens)",
"c-x3-c motif chemokine receptor 1 (homo sapiens)",
"cc-ckr-9 (homo sapiens)",
"c-c motif chemokine receptor 3 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr3'? | [
"cxcr3 (homo sapiens)",
"c-x-c motif chemokine receptor 3 (homo sapiens)"
] | [
"cc-ckr-3 (homo sapiens)",
"c-x3-c motif chemokine receptor 1 (homo sapiens)",
"cc-ckr-9 (homo sapiens)",
"c-c motif chemokine receptor 3 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', answer the user's query. |
What is the biomedical concept corresponding to 'gamma ip-10'? | [
"ip-10 (homo sapiens)",
"c-x-c motif chemokine ligand 10 (homo sapiens)",
"gip-10 (homo sapiens)",
"ifi10 (homo sapiens)"
] | [
"interleukin 1 family member 10 (homo sapiens)",
"interleukin 10 (homo sapiens)",
"il-10c (homo sapiens)",
"interferon alpha 10 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', answer the user's query. |
What is the biomedical concept corresponding to 'mig'? | [
"mig (homo sapiens)"
] | [
"mig-6 (homo sapiens)",
"mig1 (homo sapiens)",
"mig10 (homo sapiens)",
"mig9 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'gamma IP-10 and Mig induced chemotaxis of GM-CSF-stimulated CD34(+) progenitors by means of CXCR3, since an anti-CXCR3 monoclonal antibody (mAb) was found to block gamma IP-10-induced and Mig-induced CD34(+) progenitor chemotaxis.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'These chemotactic attracted CD34(+)', answer the user's query. |
What is the biomedical concept corresponding to 'gamma ip-10'? | [
"ip-10 (homo sapiens)",
"c-x-c motif chemokine ligand 10 (homo sapiens)",
"gip-10 (homo sapiens)",
"ifi10 (homo sapiens)"
] | [
"interleukin 1 family member 10 (homo sapiens)",
"interleukin 10 (homo sapiens)",
"il-10c (homo sapiens)",
"interferon alpha 10 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', answer the user's query. |
What is the biomedical concept corresponding to 'mig'? | [
"mig (homo sapiens)"
] | [
"mig-6 (homo sapiens)",
"mig1 (homo sapiens)",
"mig10 (homo sapiens)",
"mig9 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', answer the user's query. |
What is the biomedical concept corresponding to 'gm-csf'? | [
"colony stimulating factor 2 (homo sapiens)",
"gmcsf (homo sapiens)",
"csf2 (homo sapiens)",
"csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)",
"csf-1 (homo sapiens)",
"multi-csf (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr3'? | [
"cxcr3 (homo sapiens)",
"c-x-c motif chemokine receptor 3 (homo sapiens)"
] | [
"cc-ckr-3 (homo sapiens)",
"c-x3-c motif chemokine receptor 1 (homo sapiens)",
"cc-ckr-9 (homo sapiens)",
"c-c motif chemokine receptor 3 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr3'? | [
"cxcr3 (homo sapiens)",
"c-x-c motif chemokine receptor 3 (homo sapiens)"
] | [
"cc-ckr-3 (homo sapiens)",
"c-x3-c motif chemokine receptor 1 (homo sapiens)",
"cc-ckr-9 (homo sapiens)",
"c-c motif chemokine receptor 3 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', answer the user's query. |
What is the biomedical concept corresponding to 'gammaip-10'? | [
"ip-10 (homo sapiens)",
"gip-10 (homo sapiens)",
"ifi10 (homo sapiens)",
"c-x-c motif chemokine ligand 10 (homo sapiens)"
] | [
"interleukin 1 family member 10 (homo sapiens)",
"interleukin 10 (homo sapiens)",
"il-10c (homo sapiens)",
"il-10a (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', answer the user's query. |
What is the biomedical concept corresponding to 'mig'? | [
"mig (homo sapiens)"
] | [
"mig-6 (homo sapiens)",
"mig1 (homo sapiens)",
"mig10 (homo sapiens)",
"mig9 (homo sapiens)"
] | Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', answer the user's query. |
What is the biomedical concept corresponding to 'chemokine stromal cell-derived factor 1 alpha'? | [
"sdf1 (homo sapiens)"
] | [
"mip-1-alpha (homo sapiens)",
"sdf-1a (xenopus tropicalis)",
"sdf1a (xenopus tropicalis)",
"sdf1 (xenopus tropicalis)"
] | Given the context 'gamma IP-10 and Mig also induced GM-CSF-stimulated CD34(+) progenitor adhesion and aggregation by means of CXCR3, a finding confirmed by the observation that anti-CXCR3 mAb blocked these functions of gammaIP-10 and Mig but not of chemokine stromal cell-derived factor 1 alpha.', answer the user's query. |
What is the biomedical concept corresponding to 'gamma ip-10'? | [
"ip-10 (homo sapiens)",
"c-x-c motif chemokine ligand 10 (homo sapiens)",
"gip-10 (homo sapiens)",
"ifi10 (homo sapiens)"
] | [
"interleukin 1 family member 10 (homo sapiens)",
"interleukin 10 (homo sapiens)",
"il-10c (homo sapiens)",
"interferon alpha 10 (homo sapiens)"
] | Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', answer the user's query. |
What is the biomedical concept corresponding to 'mig'? | [
"mig (homo sapiens)"
] | [
"mig-6 (homo sapiens)",
"mig1 (homo sapiens)",
"mig10 (homo sapiens)",
"mig9 (homo sapiens)"
] | Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', answer the user's query. |
What is the biomedical concept corresponding to 'cd49a'? | [
"cd49a (homo sapiens)"
] | [
"itga9 (homo sapiens)",
"cd49fa (homo sapiens)",
"integrin subunit alpha 9 (homo sapiens)",
"cd49b (homo sapiens)"
] | Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', answer the user's query. |
What is the biomedical concept corresponding to 'cd49b'? | [
"cd49b (homo sapiens)"
] | [
"cd49c (homo sapiens)",
"cd41b (homo sapiens)",
"cd49e (homo sapiens)",
"glycoprotein ib platelet subunit beta (homo sapiens)"
] | Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', answer the user's query. |
What is the biomedical concept corresponding to 'gm-csf'? | [
"colony stimulating factor 2 (homo sapiens)",
"gmcsf (homo sapiens)",
"csf2 (homo sapiens)",
"csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)",
"csf-1 (homo sapiens)",
"multi-csf (homo sapiens)"
] | Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'gamma IP-10-induced and Mig-induced up-regulation of integrins (CD49a and CD49b) was found to play a crucial role in adhesion of GM-CSF-stimulated CD34(+)', answer the user's query. |
What is the biomedical concept corresponding to 'gamma ip-10'? | [
"ip-10 (homo sapiens)",
"c-x-c motif chemokine ligand 10 (homo sapiens)",
"gip-10 (homo sapiens)",
"ifi10 (homo sapiens)"
] | [
"interleukin 1 family member 10 (homo sapiens)",
"interleukin 10 (homo sapiens)",
"il-10c (homo sapiens)",
"interferon alpha 10 (homo sapiens)"
] | Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'mig'? | [
"mig (homo sapiens)"
] | [
"mig-6 (homo sapiens)",
"mig1 (homo sapiens)",
"mig10 (homo sapiens)",
"mig9 (homo sapiens)"
] | Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr3'? | [
"cxcr3 (homo sapiens)",
"c-x-c motif chemokine receptor 3 (homo sapiens)"
] | [
"cc-ckr-3 (homo sapiens)",
"c-x3-c motif chemokine receptor 1 (homo sapiens)",
"cc-ckr-9 (homo sapiens)",
"c-c motif chemokine receptor 3 (homo sapiens)"
] | Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'gm-csf'? | [
"colony stimulating factor 2 (homo sapiens)",
"gmcsf (homo sapiens)",
"csf2 (homo sapiens)",
"csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)",
"csf-1 (homo sapiens)",
"multi-csf (homo sapiens)"
] | Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'Moreover, gamma IP-10 and Mig stimulated CXCR3 redistribution and cellular polarization in GM-CSF-stimulated CD34(+) progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr3'? | [
"cxcr3 (homo sapiens)",
"c-x-c motif chemokine receptor 3 (homo sapiens)"
] | [
"cc-ckr-3 (homo sapiens)",
"c-x3-c motif chemokine receptor 1 (homo sapiens)",
"cc-ckr-9 (homo sapiens)",
"c-c motif chemokine receptor 3 (homo sapiens)"
] | Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progenitors into lymphoid and myeloid stem cells, subsequently immune and inflammatory cells.', answer the user's query. |
What is the biomedical concept corresponding to 'gamma ip-10'? | [
"ip-10 (homo sapiens)",
"c-x-c motif chemokine ligand 10 (homo sapiens)",
"gip-10 (homo sapiens)",
"ifi10 (homo sapiens)"
] | [
"interleukin 1 family member 10 (homo sapiens)",
"interleukin 10 (homo sapiens)",
"il-10c (homo sapiens)",
"interferon alpha 10 (homo sapiens)"
] | Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progenitors into lymphoid and myeloid stem cells, subsequently immune and inflammatory cells.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr3'? | [
"cxcr3 (homo sapiens)",
"c-x-c motif chemokine receptor 3 (homo sapiens)"
] | [
"cc-ckr-3 (homo sapiens)",
"c-x3-c motif chemokine receptor 1 (homo sapiens)",
"cc-ckr-9 (homo sapiens)",
"c-c motif chemokine receptor 3 (homo sapiens)"
] | Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progenitors into lymphoid and myeloid stem cells, subsequently immune and inflammatory cells.', answer the user's query. |
What is the biomedical concept corresponding to 'mig'? | [
"mig (homo sapiens)"
] | [
"mig-6 (homo sapiens)",
"mig1 (homo sapiens)",
"mig10 (homo sapiens)",
"mig9 (homo sapiens)"
] | Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progenitors into lymphoid and myeloid stem cells, subsequently immune and inflammatory cells.', answer the user's query. |
What is the biomedical concept corresponding to 'gm-csf'? | [
"colony stimulating factor 2 (homo sapiens)",
"gmcsf (homo sapiens)",
"csf2 (homo sapiens)",
"csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)",
"csf-1 (homo sapiens)",
"multi-csf (homo sapiens)"
] | Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progenitors into lymphoid and myeloid stem cells, subsequently immune and inflammatory cells.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'These results indicate that CXCR3-gamma IP-10 and CXCR3-Mig receptor-ligand pairs, as well as the effects of GM-CSF on them, may be especially important in the cytokine/chemokine environment for the physiologic and pathophysiologic events of differentiation of CD34(+) hematopoietic progenitors into lymphoid and myeloid stem cells, subsequently immune and inflammatory cells.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 (gallus gallus)",
"cd34 molecule (gallus gallus)",
"cd34 (sus scrofa)"
] | Given the context 'These processes include transmigration, relocation, differentiation, and maturation of CD34(+) hematopoietic progenitors.', answer the user's query. |
What is the biomedical concept corresponding to 'gp120'? | [
"env (human immunodeficiency virus 1)",
"envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1)"
] | [
"gp120 (homo sapiens)",
"nef (human immunodeficiency virus 1)",
"envelope glycoprotein c (human alphaherpesvirus 1)",
"vif (human immunodeficiency virus 1)"
] | Given the context 'HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases.
', answer the user's query. |
What is the biomedical concept corresponding to 'gp160'? | [
"envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1)"
] | [
"gp160 (homo sapiens)",
"gp160 (mus musculus)",
"mg160 (homo sapiens)",
"gp160 (rattus norvegicus)"
] | Given the context 'HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases.
', answer the user's query. |
What is the biomedical concept corresponding to 'alpha-chemokine receptor cxcr4'? | [
"cxcr4 (homo sapiens)",
"c-x-c motif chemokine receptor 4 (homo sapiens)"
] | [
"c-x-c motif chemokine receptor 4 (xenopus tropicalis)",
"c-c motif chemokine receptor 4 (homo sapiens)",
"atypical chemokine receptor 4 (xenopus tropicalis)",
"c-c chemokine receptor type 8 (xenopus tropicalis)"
] | Given the context 'Recently, the alpha-chemokine receptor CXCR4 has been reported to mediate apoptosis in neuronal cells and in CD4(+) and CD8(+) T cells after its binding to HIV-1 envelope proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'gp120/160'? | [
"envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1)",
"env (human immunodeficiency virus 1)"
] | [
"gp160 (homo sapiens)",
"hhv5wtgp160 (human betaherpesvirus 5)",
"mg-160 (rattus norvegicus)",
"gp120 (homo sapiens)"
] | Given the context 'In the current study, it was observed that human umbilical vein endothelial cells (HUVEC) undergo apoptosis after their treatment with the HIV-1 envelope proteins gp120/160.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr4'? | [
"cxcr4 (homo sapiens)",
"c-x-c motif chemokine receptor 4 (homo sapiens)"
] | [
"c-x-c motif chemokine receptor 4 (xenopus tropicalis)",
"c-c motif chemokine receptor 4 (homo sapiens)",
"atypical chemokine receptor 4 (xenopus tropicalis)",
"cc-ckr-4 (homo sapiens)"
] | Given the context 'Anti-CXCR4 monoclonal antibody decreased HIV-1 gp120/160-induced apoptosis, suggesting that the CXCR4 chemokine receptor mediates the apoptotic effects of these HIV envelope glycoproteins.', answer the user's query. |
What is the biomedical concept corresponding to 'gp120/160'? | [
"envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1)",
"env (human immunodeficiency virus 1)"
] | [
"gp160 (homo sapiens)",
"hhv5wtgp160 (human betaherpesvirus 5)",
"mg-160 (rattus norvegicus)",
"gp120 (homo sapiens)"
] | Given the context 'Anti-CXCR4 monoclonal antibody decreased HIV-1 gp120/160-induced apoptosis, suggesting that the CXCR4 chemokine receptor mediates the apoptotic effects of these HIV envelope glycoproteins.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr4'? | [
"cxcr4 (homo sapiens)",
"c-x-c motif chemokine receptor 4 (homo sapiens)"
] | [
"c-x-c motif chemokine receptor 4 (xenopus tropicalis)",
"c-c motif chemokine receptor 4 (homo sapiens)",
"atypical chemokine receptor 4 (xenopus tropicalis)",
"cc-ckr-4 (homo sapiens)"
] | Given the context 'Anti-CXCR4 monoclonal antibody decreased HIV-1 gp120/160-induced apoptosis, suggesting that the CXCR4 chemokine receptor mediates the apoptotic effects of these HIV envelope glycoproteins.', answer the user's query. |
What is the biomedical concept corresponding to 'gp120/160'? | [
"envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1)",
"env (human immunodeficiency virus 1)"
] | [
"gp160 (homo sapiens)",
"hhv5wtgp160 (human betaherpesvirus 5)",
"mg-160 (rattus norvegicus)",
"gp120 (homo sapiens)"
] | Given the context 'Further studies revealed that caspases play an important role in this process because the pretreatment of cells with a general caspase enzyme inhibitor decreased the extent of HUVEC apoptosis induced by gp120/160.', answer the user's query. |
What is the biomedical concept corresponding to 'caspase-3'? | [
"casp3 (homo sapiens)",
"caspase 3 (homo sapiens)"
] | [
"caspase 3 (drosophila melanogaster) (death related ice-like caspase (drosophila melanogaster))",
"ich-3 (homo sapiens)",
"ice-lap3 (homo sapiens)",
"caspase-3 (mus musculus)"
] | Given the context 'In addition, it was found that caspase-3 was activated on HIV-1 gp120/160 treatment of these cells.', answer the user's query. |
What is the biomedical concept corresponding to 'gp120/160'? | [
"envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1)",
"env (human immunodeficiency virus 1)"
] | [
"gp160 (homo sapiens)",
"hhv5wtgp160 (human betaherpesvirus 5)",
"mg-160 (rattus norvegicus)",
"gp120 (homo sapiens)"
] | Given the context 'In addition, it was found that caspase-3 was activated on HIV-1 gp120/160 treatment of these cells.', answer the user's query. |
What is the biomedical concept corresponding to 'gp120/160'? | [
"envelope surface glycoprotein gp160, precursor (human immunodeficiency virus 1)",
"env (human immunodeficiency virus 1)"
] | [
"gp160 (homo sapiens)",
"hhv5wtgp160 (human betaherpesvirus 5)",
"mg-160 (rattus norvegicus)",
"gp120 (homo sapiens)"
] | Given the context 'It was also observed that gp120/160 treatment slightly increased the expression of the pro-apoptotic molecule Bax.', answer the user's query. |
What is the biomedical concept corresponding to 'bax'? | [
"bax (homo sapiens)",
"bcl2 associated x, apoptosis regulator (homo sapiens)"
] | [
"bak1 (homo sapiens)",
"bak-like (homo sapiens)",
"bcl-x (homo sapiens)",
"bak (homo sapiens)"
] | Given the context 'It was also observed that gp120/160 treatment slightly increased the expression of the pro-apoptotic molecule Bax.', answer the user's query. |
What is the biomedical concept corresponding to 'cxcr4'? | [
"cxcr4 (homo sapiens)",
"c-x-c motif chemokine receptor 4 (homo sapiens)"
] | [
"c-x-c motif chemokine receptor 4 (xenopus tropicalis)",
"c-c motif chemokine receptor 4 (homo sapiens)",
"atypical chemokine receptor 4 (xenopus tropicalis)",
"cc-ckr-4 (homo sapiens)"
] | Given the context 'These results suggest that HIV-1 envelope glycoproteins can disrupt endothelial integrity through the interaction with CXCR4, thereby facilitating virus transit out of the bloodstream and contributing to the vascular injury syndromes seen in acquired immunodeficiency syndrome.', answer the user's query. |
What is the biomedical concept corresponding to 'collagen xviii'? | [
"collagen type xviii alpha 1 chain (homo sapiens)"
] | [
"collagen type xviii alpha 1 (xenopus tropicalis)",
"collagen alpha-1(xxviii) chain (xenopus tropicalis)",
"collagen alpha-1(xxviii) chain (xenopus laevis)",
"collagen, type xxviii, alpha 1 (xenopus tropicalis)"
] | Given the context 'Collagen XVIII, containing an endogenous inhibitor of angiogenesis and tumor growth, plays a critical role in the maintenance of retinal structure and in neural tube closure (Knobloch syndrome).
', answer the user's query. |
What is the biomedical concept corresponding to 'col18a1'? | [
"col18a1 (homo sapiens)"
] | [
"col18a1 (xenopus tropicalis)",
"col18a1 (xenopus laevis)",
"col18a1 (bos taurus)",
"col18a1a (danio rerio)"
] | Given the context 'We reconstructed the haplotypes of this family with ten additional markers (five were novel) and narrowed the candidate interval to a region of < 245 kb, which contains 24 expressed sequence tags, the KIAA0958 gene and the 5' end of the COL18A1 gene.', answer the user's query. |
What is the biomedical concept corresponding to 'col18a1'? | [
"col18a1 (homo sapiens)"
] | [
"col18a1 (xenopus tropicalis)",
"col18a1 (xenopus laevis)",
"col18a1 (bos taurus)",
"col18a1a (danio rerio)"
] | Given the context 'We identified a homozygous mutation at the AG consensus acceptor splice site of COL18A1 intron 1 exclusively among the 12 KS patients, which was not found among 140 control chromosomes.', answer the user's query. |
What is the biomedical concept corresponding to 'alpha1(xviii) collagen'? | [
"collagen type xviii alpha 1 chain (homo sapiens)"
] | [
"collagen alpha-1(xxviii) chain (xenopus laevis)",
"collagen alpha-1(xxviii) chain (xenopus tropicalis)",
"collagen type xviii alpha 1 (xenopus tropicalis)",
"collagen type xxviii alpha 1 chain (homo sapiens)"
] | Given the context 'This mutation predicts the creation of a stop codon in exon 4 and therefore the truncation of the alpha1(XVIII) collagen short form, which was expressed in human adult retina.', answer the user's query. |
What is the biomedical concept corresponding to 'col18a1'? | [
"col18a1 (homo sapiens)"
] | [
"col18a1 (xenopus tropicalis)",
"col18a1 (xenopus laevis)",
"col18a1 (bos taurus)",
"col18a1a (danio rerio)"
] | Given the context 'These findings provide evidence that KS is caused by mutations in COL18A1 which, therefore, has a major role in determining the retinal structure as well as in the closure of the neural tube.', answer the user's query. |
What is the biomedical concept corresponding to 'ciks'? | [
"ciks (homo sapiens)"
] | [
"ciks (mus musculus)",
"cisk (homo sapiens)",
"citk (homo sapiens)",
"adapter protein ciks (xenopus tropicalis)"
] | Given the context 'CIKS, a connection to Ikappa B kinase and stress-activated protein kinase.
', answer the user's query. |
What is the biomedical concept corresponding to 'ikkalpha'? | [
"ikk-alpha (homo sapiens)",
"ikka (homo sapiens)",
"ikk-1 (homo sapiens)",
"ikk1 (homo sapiens)"
] | [
"ikk-i (homo sapiens)",
"ikki (homo sapiens)",
"ikkb (homo sapiens)",
"nfkbia (homo sapiens)"
] | Given the context 'IKKalpha and IKKbeta are two catalytic subunits of a core IKK complex that also contains the regulatory subunit NEMO (NF-kappaB essential modulator)/IKKgamma.', answer the user's query. |
What is the biomedical concept corresponding to 'ikkbeta'? | [
"ikk-beta (homo sapiens)",
"ikkb (homo sapiens)",
"ikk-2 (homo sapiens)",
"nfkbikb (homo sapiens)",
"ikk2 (homo sapiens)"
] | [
"nfkbib (homo sapiens)",
"ikk-beta (mus musculus)",
"ikk-beta (xenopus tropicalis)",
"ikkbeta (mus musculus)"
] | Given the context 'IKKalpha and IKKbeta are two catalytic subunits of a core IKK complex that also contains the regulatory subunit NEMO (NF-kappaB essential modulator)/IKKgamma.', answer the user's query. |
What is the biomedical concept corresponding to 'nemo'? | [
"nemo (homo sapiens)"
] | [
"nemo (mus musculus)",
"nemo (drosophila melanogaster)",
"nemep (mus musculus)",
"nemo/nlk (drosophila melanogaster)"
] | Given the context 'IKKalpha and IKKbeta are two catalytic subunits of a core IKK complex that also contains the regulatory subunit NEMO (NF-kappaB essential modulator)/IKKgamma.', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kappab essential modulator'? | [
"nemo (homo sapiens)"
] | [
"nemo (drosophila melanogaster)",
"nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus)",
"nemo/nlk (drosophila melanogaster)",
"nemep (homo sapiens)"
] | Given the context 'IKKalpha and IKKbeta are two catalytic subunits of a core IKK complex that also contains the regulatory subunit NEMO (NF-kappaB essential modulator)/IKKgamma.', answer the user's query. |
What is the biomedical concept corresponding to 'ikkgamma'? | [
"ikk-gamma (homo sapiens)",
"ikkg (homo sapiens)"
] | [
"ikkgamma (drosophila melanogaster)",
"ikk-alpha (homo sapiens)",
"ikk-beta (homo sapiens)",
"ikkgammabeta (drosophila melanogaster)"
] | Given the context 'IKKalpha and IKKbeta are two catalytic subunits of a core IKK complex that also contains the regulatory subunit NEMO (NF-kappaB essential modulator)/IKKgamma.', answer the user's query. |
What is the biomedical concept corresponding to 'ciks'? | [
"ciks (homo sapiens)"
] | [
"ciks (mus musculus)",
"cisk (homo sapiens)",
"citk (homo sapiens)",
"adapter protein ciks (xenopus tropicalis)"
] | Given the context 'Here we describe the molecular cloning of CIKS (connection to IKK and SAPK/JNK), a previously unknown protein that directly interacts with NEMO/IKKgamma in cells.', answer the user's query. |
What is the biomedical concept corresponding to 'nemo'? | [
"nemo (homo sapiens)"
] | [
"nemo (mus musculus)",
"nemo (drosophila melanogaster)",
"nemep (mus musculus)",
"nemo/nlk (drosophila melanogaster)"
] | Given the context 'Here we describe the molecular cloning of CIKS (connection to IKK and SAPK/JNK), a previously unknown protein that directly interacts with NEMO/IKKgamma in cells.', answer the user's query. |
What is the biomedical concept corresponding to 'ikkgamma'? | [
"ikk-gamma (homo sapiens)",
"ikkg (homo sapiens)"
] | [
"ikkgamma (drosophila melanogaster)",
"ikk-alpha (homo sapiens)",
"ikk-beta (homo sapiens)",
"ikkgammabeta (drosophila melanogaster)"
] | Given the context 'Here we describe the molecular cloning of CIKS (connection to IKK and SAPK/JNK), a previously unknown protein that directly interacts with NEMO/IKKgamma in cells.', answer the user's query. |
What is the biomedical concept corresponding to 'ciks'? | [
"ciks (homo sapiens)"
] | [
"ciks (mus musculus)",
"cisk (homo sapiens)",
"citk (homo sapiens)",
"adapter protein ciks (xenopus tropicalis)"
] | Given the context 'When ectopically expressed, CIKS stimulates IKK and SAPK/JNK kinases and it transactivates an NF-kappaB-dependent reporter.', answer the user's query. |
What is the biomedical concept corresponding to 'ciks'? | [
"ciks (homo sapiens)"
] | [
"ciks (mus musculus)",
"cisk (homo sapiens)",
"citk (homo sapiens)",
"adapter protein ciks (xenopus tropicalis)"
] | Given the context 'CIKS may help to connect upstream signaling events to IKK and SAPK/JNK modules.', answer the user's query. |
What is the biomedical concept corresponding to 'ciks'? | [
"ciks (homo sapiens)"
] | [
"ciks (mus musculus)",
"cisk (homo sapiens)",
"citk (homo sapiens)",
"adapter protein ciks (xenopus tropicalis)"
] | Given the context 'CIKS could coordinate the activation of two stress-induced signaling pathways, functions reminiscent of those noted for tumor necrosis factor receptor-associated factor adaptor proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'smad4'? | [
"smad4 (homo sapiens)",
"smad family member 4 (homo sapiens)",
"dpc4 (homo sapiens)",
"madh4 (homo sapiens)"
] | [
"smad4 (mus musculus)",
"smad family member 4 (mus musculus)",
"smad family member 5 (homo sapiens)",
"smad family member 4 (xenopus tropicalis)"
] | Given the context 'Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4.
', answer the user's query. |
What is the biomedical concept corresponding to 'smad3'? | [
"smad3 (homo sapiens)",
"smad family member 3 (homo sapiens)",
"mad3 (homo sapiens) (smad family member 3 (homo sapiens))",
"madh3 (homo sapiens)"
] | [
"smad3 (mus musculus)",
"mad-3 (homo sapiens)",
"smad3 (xenopus laevis) (smad family member 3 s homeolog (xenopus laevis))",
"smad family member 3 (mus musculus)"
] | Given the context 'Certain of these mutations affect the Smad amino-terminal domain, which, in the case of Smad3 and Smad4, binds DNA.', answer the user's query. |
What is the biomedical concept corresponding to 'smad4'? | [
"smad4 (homo sapiens)",
"smad family member 4 (homo sapiens)",
"dpc4 (homo sapiens)",
"madh4 (homo sapiens)"
] | [
"smad4 (mus musculus)",
"smad family member 4 (mus musculus)",
"smad family member 5 (homo sapiens)",
"smad family member 4 (xenopus tropicalis)"
] | Given the context 'Certain of these mutations affect the Smad amino-terminal domain, which, in the case of Smad3 and Smad4, binds DNA.', answer the user's query. |
What is the biomedical concept corresponding to 'smad4'? | [
"smad4 (homo sapiens)",
"smad family member 4 (homo sapiens)",
"dpc4 (homo sapiens)",
"madh4 (homo sapiens)"
] | [
"smad4 (mus musculus)",
"smad family member 4 (mus musculus)",
"smad family member 5 (homo sapiens)",
"smad family member 4 (xenopus tropicalis)"
] | Given the context 'We investigated the functional consequences of four missense mutations in the Smad4 amino-terminal domain found in human tumors.', answer the user's query. |
What is the biomedical concept corresponding to 'smad3'? | [
"smad3 (homo sapiens)",
"smad family member 3 (homo sapiens)",
"mad3 (homo sapiens) (smad family member 3 (homo sapiens))",
"madh3 (homo sapiens)"
] | [
"smad3 (mus musculus)",
"mad-3 (homo sapiens)",
"smad3 (xenopus laevis) (smad family member 3 s homeolog (xenopus laevis))",
"smad family member 3 (mus musculus)"
] | Given the context 'The mutant proteins were found to have impaired abilities to bind DNA although they were fully capable of forming complexes with Smad3.', answer the user's query. |
What is the biomedical concept corresponding to 'smad4'? | [
"smad4 (homo sapiens)",
"smad family member 4 (homo sapiens)",
"dpc4 (homo sapiens)",
"madh4 (homo sapiens)"
] | [
"smad4 (mus musculus)",
"smad family member 4 (mus musculus)",
"smad family member 5 (homo sapiens)",
"smad family member 4 (xenopus tropicalis)"
] | Given the context 'All four Smad4 mutants showed decreased protein stability compared to wild-type Smad4.', answer the user's query. |
What is the biomedical concept corresponding to 'smad4'? | [
"smad4 (homo sapiens)",
"smad family member 4 (homo sapiens)",
"dpc4 (homo sapiens)",
"madh4 (homo sapiens)"
] | [
"smad4 (mus musculus)",
"smad family member 4 (mus musculus)",
"smad family member 5 (homo sapiens)",
"smad family member 4 (xenopus tropicalis)"
] | Given the context 'All four Smad4 mutants showed decreased protein stability compared to wild-type Smad4.', answer the user's query. |
What is the biomedical concept corresponding to 'smad4'? | [
"smad4 (homo sapiens)",
"smad family member 4 (homo sapiens)",
"dpc4 (homo sapiens)",
"madh4 (homo sapiens)"
] | [
"smad4 (mus musculus)",
"smad family member 4 (mus musculus)",
"smad family member 5 (homo sapiens)",
"smad family member 4 (xenopus tropicalis)"
] | Given the context 'Two of the Smad4 mutants (G65V and P130S) were translocated to the nucleus and were capable of transactivating a Smad-dependent promoter in a ligand-dependent manner.', answer the user's query. |
What is the biomedical concept corresponding to 'smad3'? | [
"smad3 (homo sapiens)",
"smad family member 3 (homo sapiens)",
"mad3 (homo sapiens) (smad family member 3 (homo sapiens))",
"madh3 (homo sapiens)"
] | [
"smad3 (mus musculus)",
"mad-3 (homo sapiens)",
"smad3 (xenopus laevis) (smad family member 3 s homeolog (xenopus laevis))",
"smad family member 3 (mus musculus)"
] | Given the context 'Moreover, we demonstrate here the critical importance of two basic residues in the beta-hairpin loop of Smad3 or Smad4 for DNA binding, consistent with predictions from the Smad3 crystal structure.', answer the user's query. |
What is the biomedical concept corresponding to 'smad4'? | [
"smad4 (homo sapiens)",
"smad family member 4 (homo sapiens)",
"dpc4 (homo sapiens)",
"madh4 (homo sapiens)"
] | [
"smad4 (mus musculus)",
"smad family member 4 (mus musculus)",
"smad family member 5 (homo sapiens)",
"smad family member 4 (xenopus tropicalis)"
] | Given the context 'Moreover, we demonstrate here the critical importance of two basic residues in the beta-hairpin loop of Smad3 or Smad4 for DNA binding, consistent with predictions from the Smad3 crystal structure.', answer the user's query. |
What is the biomedical concept corresponding to 'smad3'? | [
"smad3 (homo sapiens)",
"smad family member 3 (homo sapiens)",
"mad3 (homo sapiens) (smad family member 3 (homo sapiens))",
"madh3 (homo sapiens)"
] | [
"smad3 (mus musculus)",
"mad-3 (homo sapiens)",
"smad3 (xenopus laevis) (smad family member 3 s homeolog (xenopus laevis))",
"smad family member 3 (mus musculus)"
] | Given the context 'Moreover, we demonstrate here the critical importance of two basic residues in the beta-hairpin loop of Smad3 or Smad4 for DNA binding, consistent with predictions from the Smad3 crystal structure.', answer the user's query. |
What is the biomedical concept corresponding to 'smad4'? | [
"smad4 (homo sapiens)",
"smad family member 4 (homo sapiens)",
"dpc4 (homo sapiens)",
"madh4 (homo sapiens)"
] | [
"smad4 (mus musculus)",
"smad family member 4 (mus musculus)",
"smad family member 5 (homo sapiens)",
"smad family member 4 (xenopus tropicalis)"
] | Given the context 'In addition, our results reveal that in the TGF-beta-induced heteromeric signaling complex, loss of DNA binding of Smad4 can be compensated by Smad3, however, both Smad3 and Smad4 are needed for efficient DNA binding and signaling.', answer the user's query. |
What is the biomedical concept corresponding to 'smad3'? | [
"smad3 (homo sapiens)",
"smad family member 3 (homo sapiens)",
"mad3 (homo sapiens) (smad family member 3 (homo sapiens))",
"madh3 (homo sapiens)"
] | [
"smad3 (mus musculus)",
"mad-3 (homo sapiens)",
"smad3 (xenopus laevis) (smad family member 3 s homeolog (xenopus laevis))",
"smad family member 3 (mus musculus)"
] | Given the context 'In addition, our results reveal that in the TGF-beta-induced heteromeric signaling complex, loss of DNA binding of Smad4 can be compensated by Smad3, however, both Smad3 and Smad4 are needed for efficient DNA binding and signaling.', answer the user's query. |
What is the biomedical concept corresponding to 'smad3'? | [
"smad3 (homo sapiens)",
"smad family member 3 (homo sapiens)",
"mad3 (homo sapiens) (smad family member 3 (homo sapiens))",
"madh3 (homo sapiens)"
] | [
"smad3 (mus musculus)",
"mad-3 (homo sapiens)",
"smad3 (xenopus laevis) (smad family member 3 s homeolog (xenopus laevis))",
"smad family member 3 (mus musculus)"
] | Given the context 'In addition, our results reveal that in the TGF-beta-induced heteromeric signaling complex, loss of DNA binding of Smad4 can be compensated by Smad3, however, both Smad3 and Smad4 are needed for efficient DNA binding and signaling.', answer the user's query. |
What is the biomedical concept corresponding to 'smad4'? | [
"smad4 (homo sapiens)",
"smad family member 4 (homo sapiens)",
"dpc4 (homo sapiens)",
"madh4 (homo sapiens)"
] | [
"smad4 (mus musculus)",
"smad family member 4 (mus musculus)",
"smad family member 5 (homo sapiens)",
"smad family member 4 (xenopus tropicalis)"
] | Given the context 'In addition, our results reveal that in the TGF-beta-induced heteromeric signaling complex, loss of DNA binding of Smad4 can be compensated by Smad3, however, both Smad3 and Smad4 are needed for efficient DNA binding and signaling.', answer the user's query. |
What is the biomedical concept corresponding to 'smad4'? | [
"smad4 (homo sapiens)",
"smad family member 4 (homo sapiens)",
"dpc4 (homo sapiens)",
"madh4 (homo sapiens)"
] | [
"smad4 (mus musculus)",
"smad family member 4 (mus musculus)",
"smad family member 5 (homo sapiens)",
"smad family member 4 (xenopus tropicalis)"
] | Given the context 'In conclusion, mutations in the amino-terminal domain of Smad4, that are found in cancer, show loss of multiple functional properties which may contribute to tumorigenesis.', answer the user's query. |
What is the biomedical concept corresponding to 'lis1'? | [
"lis1 (homo sapiens)"
] | [
"lissencephaly-1 homolog (caenorhabditis elegans)",
"lis3 (homo sapiens)",
"lis7 (homo sapiens)",
"lis-1 (drosophila melanogaster)"
] | Given the context 'Interaction between LIS1 and doublecortin, two lissencephaly gene products.
', answer the user's query. |
What is the biomedical concept corresponding to 'doublecortin'? | [
"doublecortin (homo sapiens)",
"dcx (homo sapiens)"
] | [
"doublecortin (xenopus tropicalis)",
"doublecortin domain containing 2 (homo sapiens)",
"doublecortin (rattus norvegicus)",
"doublecortin (bos taurus)"
] | Given the context 'Interaction between LIS1 and doublecortin, two lissencephaly gene products.
', answer the user's query. |
What is the biomedical concept corresponding to 'lis1'? | [
"lis1 (homo sapiens)"
] | [
"lissencephaly-1 homolog (caenorhabditis elegans)",
"lis3 (homo sapiens)",
"lis7 (homo sapiens)",
"lis-1 (drosophila melanogaster)"
] | Given the context 'Mutations in either LIS1 or DCX are the most common cause for type I lissencephaly.', answer the user's query. |
What is the biomedical concept corresponding to 'dcx'? | [
"dcx (homo sapiens)",
"doublecortin (homo sapiens)"
] | [
"dcxr (homo sapiens)",
"dcx (rattus norvegicus)",
"doublecortin (xenopus tropicalis)",
"dcx (oryctolagus cuniculus)"
] | Given the context 'Mutations in either LIS1 or DCX are the most common cause for type I lissencephaly.', answer the user's query. |
What is the biomedical concept corresponding to 'type i lissencephaly'? | [
"lis1 (homo sapiens)"
] | [
"lissencephaly-1 homolog (caenorhabditis elegans)",
"lis7 (homo sapiens)",
"lis3 (homo sapiens)",
"lis1a (danio rerio)"
] | Given the context 'Mutations in either LIS1 or DCX are the most common cause for type I lissencephaly.', answer the user's query. |
What is the biomedical concept corresponding to 'lis1'? | [
"lis1 (homo sapiens)"
] | [
"lissencephaly-1 homolog (caenorhabditis elegans)",
"lis3 (homo sapiens)",
"lis7 (homo sapiens)",
"lis-1 (drosophila melanogaster)"
] | Given the context 'Here we report that LIS1 and DCX interact physically both in vitro and in vivo.', answer the user's query. |
What is the biomedical concept corresponding to 'dcx'? | [
"dcx (homo sapiens)",
"doublecortin (homo sapiens)"
] | [
"dcxr (homo sapiens)",
"dcx (rattus norvegicus)",
"doublecortin (xenopus tropicalis)",
"dcx (oryctolagus cuniculus)"
] | Given the context 'Here we report that LIS1 and DCX interact physically both in vitro and in vivo.', answer the user's query. |
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