query string | positive list | negative list | system string |
|---|---|---|---|
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'In human cells, separase activation also coincides with the cleavage of separase, but it is not known if this reaction activates separase, which protease cleaves separase, and how separase cleavage is regulated.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'In human cells, separase activation also coincides with the cleavage of separase, but it is not known if this reaction activates separase, which protease cleaves separase, and how separase cleavage is regulated.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'Inhibition of separase expression in human cells by RNA interference causes the formation of polyploid cells with large lobed nuclei.', answer the user's query. |
What is the biomedical concept corresponding to 'securin'? | [
"pttg1 regulator of sister chromatid separation, securin (homo sapiens)"
] | [
"provisional ortholog of pttg1 regulator of sister chromatid separation, securin (xenopus tropicalis)",
"securin (saccharomyces cerevisiae s288c)",
"securin (xenopus laevis)",
"securin (caenorhabditis elegans)"
] | Given the context 'Inhibitor binding experiments in vitro reveal that securin prevents the access of substrate analogs to the active site of separase.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'Inhibitor binding experiments in vitro reveal that securin prevents the access of substrate analogs to the active site of separase.', answer the user's query. |
What is the biomedical concept corresponding to 'securin'? | [
"pttg1 regulator of sister chromatid separation, securin (homo sapiens)"
] | [
"provisional ortholog of pttg1 regulator of sister chromatid separation, securin (xenopus tropicalis)",
"securin (saccharomyces cerevisiae s288c)",
"securin (xenopus laevis)",
"securin (caenorhabditis elegans)"
] | Given the context 'Upon securin degradation, the active site of full-length separase becomes accessible, allowing rapid autocatalytic cleavage of separase at one of three sites.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'Upon securin degradation, the active site of full-length separase becomes accessible, allowing rapid autocatalytic cleavage of separase at one of three sites.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'Upon securin degradation, the active site of full-length separase becomes accessible, allowing rapid autocatalytic cleavage of separase at one of three sites.', answer the user's query. |
What is the biomedical concept corresponding to 'securin'? | [
"pttg1 regulator of sister chromatid separation, securin (homo sapiens)"
] | [
"provisional ortholog of pttg1 regulator of sister chromatid separation, securin (xenopus tropicalis)",
"securin (saccharomyces cerevisiae s288c)",
"securin (xenopus laevis)",
"securin (caenorhabditis elegans)"
] | Given the context 'The resulting N- and C-terminal fragments remain associated and can be reinhibited by securin.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'A noncleavable separase mutant retains its ability to cleave cohesin in vitro.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'Our results suggest that separase is required for sister chromatid separation during mitosis in human cells.', answer the user's query. |
What is the biomedical concept corresponding to 'securin'? | [
"pttg1 regulator of sister chromatid separation, securin (homo sapiens)"
] | [
"provisional ortholog of pttg1 regulator of sister chromatid separation, securin (xenopus tropicalis)",
"securin (saccharomyces cerevisiae s288c)",
"securin (xenopus laevis)",
"securin (caenorhabditis elegans)"
] | Given the context 'Our data further indicate that securin inhibits separase by blocking the access of substrates to the active site of separase.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'Our data further indicate that securin inhibits separase by blocking the access of substrates to the active site of separase.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'Our data further indicate that securin inhibits separase by blocking the access of substrates to the active site of separase.', answer the user's query. |
What is the biomedical concept corresponding to 'securin'? | [
"pttg1 regulator of sister chromatid separation, securin (homo sapiens)"
] | [
"provisional ortholog of pttg1 regulator of sister chromatid separation, securin (xenopus tropicalis)",
"securin (saccharomyces cerevisiae s288c)",
"securin (xenopus laevis)",
"securin (caenorhabditis elegans)"
] | Given the context 'Securin proteolysis allows autocatalytic processing of separase into a cleaved form, but separase cleavage is not essential for separase activation.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'Securin proteolysis allows autocatalytic processing of separase into a cleaved form, but separase cleavage is not essential for separase activation.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'Securin proteolysis allows autocatalytic processing of separase into a cleaved form, but separase cleavage is not essential for separase activation.', answer the user's query. |
What is the biomedical concept corresponding to 'separase'? | [
"extra spindle pole bodies like 1, separase (homo sapiens)",
"esp1 (homo sapiens) (extra spindle pole bodies like 1, separase (homo sapiens))"
] | [
"separase (saccharomyces cerevisiae s288c)",
"separase (drosophila melanogaster)",
"separin homolog sep-1 (caenorhabditis elegans)",
"separase (candida albicans sc5314)"
] | Given the context 'Securin proteolysis allows autocatalytic processing of separase into a cleaved form, but separase cleavage is not essential for separase activation.', answer the user's query. |
What is the biomedical concept corresponding to 'cd3 gamma'? | [
"cd3 gamma subunit of t-cell receptor complex (homo sapiens)",
"cd3-gammaamma (homo sapiens)",
"cd3g (homo sapiens) (cd3 gamma subunit of t-cell receptor complex (homo sapiens))"
] | [
"cd3g (homo sapiens) (tcr gamma alternate reading frame protein (homo sapiens))",
"interleukin 2 receptor subunit gamma (homo sapiens)",
"cd3 gamma subunit of t-cell receptor complex (bos taurus)",
"cd3 antigen, gamma polypeptide (mus musculus)"
] | Given the context 'Contribution of CD3 gamma to TCR regulation and signaling in human mature T lymphocytes.
', answer the user's query. |
What is the biomedical concept corresponding to 'cd3 gamma'? | [
"cd3 gamma subunit of t-cell receptor complex (homo sapiens)",
"cd3-gammaamma (homo sapiens)",
"cd3g (homo sapiens) (cd3 gamma subunit of t-cell receptor complex (homo sapiens))"
] | [
"cd3g (homo sapiens) (tcr gamma alternate reading frame protein (homo sapiens))",
"interleukin 2 receptor subunit gamma (homo sapiens)",
"cd3 gamma subunit of t-cell receptor complex (bos taurus)",
"cd3 antigen, gamma polypeptide (mus musculus)"
] | Given the context 'We report here on the participation of CD3 gamma in the activation and effector function of human mature T lymphocytes at the antigen recognition checkpoint.', answer the user's query. |
What is the biomedical concept corresponding to 'cd3 gamma'? | [
"cd3 gamma subunit of t-cell receptor complex (homo sapiens)",
"cd3-gammaamma (homo sapiens)",
"cd3g (homo sapiens) (cd3 gamma subunit of t-cell receptor complex (homo sapiens))"
] | [
"cd3g (homo sapiens) (tcr gamma alternate reading frame protein (homo sapiens))",
"interleukin 2 receptor subunit gamma (homo sapiens)",
"cd3 gamma subunit of t-cell receptor complex (bos taurus)",
"cd3 antigen, gamma polypeptide (mus musculus)"
] | Given the context 'Following TCR-CD3 engagement of human CD3 gamma-deficient T cell lines, and despite their lower TCR-CD3 surface levels compared to normal controls, mature T cell responses such as protein tyrosine phosphorylation and the regulation of expression of several cell surface molecules, including the TCR-CD3 itself, were either normal or only slightly affected.', answer the user's query. |
What is the biomedical concept corresponding to 'icam-1'? | [
"icam1 (homo sapiens)",
"intercellular adhesion molecule 1 (homo sapiens)"
] | [
"icam5 (homo sapiens)",
"icam2 (homo sapiens)",
"icam4 (homo sapiens)",
"icam-r (homo sapiens)"
] | Given the context 'In contrast, other physiological responses like the specific adhesion and concomitant cell polarization on ICAM-1-coated dishes were selectively defective, and activation-induced cell death was increased.', answer the user's query. |
What is the biomedical concept corresponding to 'cd3 gamma'? | [
"cd3 gamma subunit of t-cell receptor complex (homo sapiens)",
"cd3-gammaamma (homo sapiens)",
"cd3g (homo sapiens) (cd3 gamma subunit of t-cell receptor complex (homo sapiens))"
] | [
"cd3g (homo sapiens) (tcr gamma alternate reading frame protein (homo sapiens))",
"interleukin 2 receptor subunit gamma (homo sapiens)",
"cd3 gamma subunit of t-cell receptor complex (bos taurus)",
"cd3 antigen, gamma polypeptide (mus musculus)"
] | Given the context 'Our data indicate that CD3 gamma contributes essential specialized signaling functions to certain mature T cell responses.', answer the user's query. |
What is the biomedical concept corresponding to 'adam10'? | [
"adam10 (homo sapiens)",
"adam metallopeptidase domain 10 (homo sapiens)",
"ad10 (homo sapiens) (adam metallopeptidase domain 10 (homo sapiens))"
] | [
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam-ts10 (homo sapiens)",
"adam metallopeptidase with thrombospondin type 1 motif 10 (homo sapiens)",
"metalloproteinase adam10-like (xenopus tropicalis)"
] | Given the context 'ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles.
', answer the user's query. |
What is the biomedical concept corresponding to 'l1 adhesion molecule'? | [
"l1 cell adhesion molecule (homo sapiens)",
"l1cam (homo sapiens)",
"n-cam-l1 (homo sapiens)"
] | [
"adhesion g protein-coupled receptor l1 (homo sapiens)",
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"cell adhesion molecule l1 like (homo sapiens)"
] | Given the context 'ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles.
', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'L1, an important molecule for cell migration of neural and tumor cells, is released by membrane-proximal cleavage, and soluble L1 promotes cell migration.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'L1, an important molecule for cell migration of neural and tumor cells, is released by membrane-proximal cleavage, and soluble L1 promotes cell migration.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'Release of L1 is enhanced by shedding inducers such as phorbol ester and pervanadate, but it is also enhanced by depletion of cellular cholesterol with methyl-beta-cyclodextrin (MCD).', answer the user's query. |
What is the biomedical concept corresponding to 'adam10'? | [
"adam10 (homo sapiens)",
"adam metallopeptidase domain 10 (homo sapiens)",
"ad10 (homo sapiens) (adam metallopeptidase domain 10 (homo sapiens))"
] | [
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam-ts10 (homo sapiens)",
"adam metallopeptidase with thrombospondin type 1 motif 10 (homo sapiens)",
"metalloproteinase adam10-like (xenopus tropicalis)"
] | Given the context 'We show here that ADAM10 is involved in L1 cleavage, which occurs at the cell surface and in the Golgi apparatus.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'We show here that ADAM10 is involved in L1 cleavage, which occurs at the cell surface and in the Golgi apparatus.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'MCD and pervanadate treatment induced the release of microvesicles containing full-length L1 and the active form of ADAM10.', answer the user's query. |
What is the biomedical concept corresponding to 'adam10'? | [
"adam10 (homo sapiens)",
"adam metallopeptidase domain 10 (homo sapiens)",
"ad10 (homo sapiens) (adam metallopeptidase domain 10 (homo sapiens))"
] | [
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam-ts10 (homo sapiens)",
"adam metallopeptidase with thrombospondin type 1 motif 10 (homo sapiens)",
"metalloproteinase adam10-like (xenopus tropicalis)"
] | Given the context 'MCD and pervanadate treatment induced the release of microvesicles containing full-length L1 and the active form of ADAM10.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'L1 cleavage occurred in isolated vesicles.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'L1-containing microvesicles could trigger haptotactic cell migration.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'Only the neural L1 form carrying the RSLE signal for clathrin-dependent endocytosis was recruited and cleaved in vesicles.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'Phorbol ester treatment activated L1 cleavage predominantly at the cell surface.', answer the user's query. |
What is the biomedical concept corresponding to 'l1'? | [
"l1 cell adhesion molecule (homo sapiens)"
] | [
"l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"l(1)l1 (drosophila melanogaster) (lethal (1) l1 (drosophila melanogaster))",
"lethal (1) l1 (drosophila melanogaster)",
"cyclin l1 (homo sapiens)"
] | Given the context 'Our results provide evidence for two pathways of L1 cleavage, based on ADAM10 localization, that can be activated differentially: 1) direct cleavage at the cell surface, and 2) release and cleavage in secretory vesicles most likely derived from the Golgi apparatus.', answer the user's query. |
What is the biomedical concept corresponding to 'adam10'? | [
"adam10 (homo sapiens)",
"adam metallopeptidase domain 10 (homo sapiens)",
"ad10 (homo sapiens) (adam metallopeptidase domain 10 (homo sapiens))"
] | [
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam-ts10 (homo sapiens)",
"adam metallopeptidase with thrombospondin type 1 motif 10 (homo sapiens)",
"metalloproteinase adam10-like (xenopus tropicalis)"
] | Given the context 'Our results provide evidence for two pathways of L1 cleavage, based on ADAM10 localization, that can be activated differentially: 1) direct cleavage at the cell surface, and 2) release and cleavage in secretory vesicles most likely derived from the Golgi apparatus.', answer the user's query. |
What is the biomedical concept corresponding to 'adam10'? | [
"adam10 (homo sapiens)",
"adam metallopeptidase domain 10 (homo sapiens)",
"ad10 (homo sapiens) (adam metallopeptidase domain 10 (homo sapiens))"
] | [
"disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans)",
"adam-ts10 (homo sapiens)",
"adam metallopeptidase with thrombospondin type 1 motif 10 (homo sapiens)",
"metalloproteinase adam10-like (xenopus tropicalis)"
] | Given the context 'The findings establish a novel role for ADAM10 as a vesicle-based protease.', answer the user's query. |
What is the biomedical concept corresponding to 'yaf2'? | [
"yaf2 (homo sapiens)"
] | [
"yaf1 (homo sapiens)",
"yaf2 (xenopus tropicalis)",
"yaf1 (saccharomyces cerevisiae s288c)",
"yaf2-b (xenopus laevis) (yy1 associated factor 2 s homeolog (xenopus laevis))"
] | Given the context 'Yaf2 inhibits Myc biological function.
', answer the user's query. |
What is the biomedical concept corresponding to 'myc'? | [
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (homo sapiens)",
"c-myc (homo sapiens)"
] | [
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))",
"v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus)",
"mycl proto-oncogene, bhlh transcription factor (homo sapiens)",
"c-myc-binding protein homolog (glycine max)"
] | Given the context 'Yaf2 inhibits Myc biological function.
', answer the user's query. |
What is the biomedical concept corresponding to 'myc'? | [
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (homo sapiens)",
"c-myc (homo sapiens)"
] | [
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))",
"v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus)",
"mycl proto-oncogene, bhlh transcription factor (homo sapiens)",
"c-myc-binding protein homolog (glycine max)"
] | Given the context 'The proto-oncogenes of the myelocytomatosis viral oncogene homolog (MYC) family, including MYC, MYCN and MYCL, encode nuclear proteins that act as transcription factors.', answer the user's query. |
What is the biomedical concept corresponding to 'mycn'? | [
"mycn proto-oncogene, bhlh transcription factor (homo sapiens)",
"mycn (homo sapiens)",
"n-myc (homo sapiens)"
] | [
"mycn (mus musculus)",
"v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus)",
"mycn, opposite strand (mus musculus)",
"mycn proto-oncogene, bhlh transcription factor (xenopus tropicalis)"
] | Given the context 'The proto-oncogenes of the myelocytomatosis viral oncogene homolog (MYC) family, including MYC, MYCN and MYCL, encode nuclear proteins that act as transcription factors.', answer the user's query. |
What is the biomedical concept corresponding to 'mycl'? | [
"mycl (homo sapiens)",
"mycl proto-oncogene, bhlh transcription factor (homo sapiens)",
"l-myc (homo sapiens)"
] | [
"mycl (mus musculus)",
"mycs-like (mus musculus)",
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"mycl2 (homo sapiens)"
] | Given the context 'The proto-oncogenes of the myelocytomatosis viral oncogene homolog (MYC) family, including MYC, MYCN and MYCL, encode nuclear proteins that act as transcription factors.', answer the user's query. |
What is the biomedical concept corresponding to 'myc'? | [
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (homo sapiens)",
"c-myc (homo sapiens)"
] | [
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))",
"v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus)",
"mycl proto-oncogene, bhlh transcription factor (homo sapiens)",
"c-myc-binding protein homolog (glycine max)"
] | Given the context 'The Myc protein is the best studied member of this family and is involved in cell cycle regulation, differentiation and cell death.', answer the user's query. |
What is the biomedical concept corresponding to 'yaf2'? | [
"yaf2 (homo sapiens)"
] | [
"yaf1 (homo sapiens)",
"yaf2 (xenopus tropicalis)",
"yaf1 (saccharomyces cerevisiae s288c)",
"yaf2-b (xenopus laevis) (yy1 associated factor 2 s homeolog (xenopus laevis))"
] | Given the context 'We have previously demonstrated that the zinc-finger protein Yaf2 interacts with the central region of MycN and enhances MycN dependent transcriptional activation.', answer the user's query. |
What is the biomedical concept corresponding to 'mycn'? | [
"mycn proto-oncogene, bhlh transcription factor (homo sapiens)",
"mycn (homo sapiens)",
"n-myc (homo sapiens)"
] | [
"mycn (mus musculus)",
"v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus)",
"mycn, opposite strand (mus musculus)",
"mycn proto-oncogene, bhlh transcription factor (xenopus tropicalis)"
] | Given the context 'We have previously demonstrated that the zinc-finger protein Yaf2 interacts with the central region of MycN and enhances MycN dependent transcriptional activation.', answer the user's query. |
What is the biomedical concept corresponding to 'mycn'? | [
"mycn proto-oncogene, bhlh transcription factor (homo sapiens)",
"mycn (homo sapiens)",
"n-myc (homo sapiens)"
] | [
"mycn (mus musculus)",
"v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus)",
"mycn, opposite strand (mus musculus)",
"mycn proto-oncogene, bhlh transcription factor (xenopus tropicalis)"
] | Given the context 'We have previously demonstrated that the zinc-finger protein Yaf2 interacts with the central region of MycN and enhances MycN dependent transcriptional activation.', answer the user's query. |
What is the biomedical concept corresponding to 'yaf2'? | [
"yaf2 (homo sapiens)"
] | [
"yaf1 (homo sapiens)",
"yaf2 (xenopus tropicalis)",
"yaf1 (saccharomyces cerevisiae s288c)",
"yaf2-b (xenopus laevis) (yy1 associated factor 2 s homeolog (xenopus laevis))"
] | Given the context 'Here we show that Yaf2 also binds to the Myc protein in vivo and in vitro.', answer the user's query. |
What is the biomedical concept corresponding to 'myc'? | [
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (homo sapiens)",
"c-myc (homo sapiens)"
] | [
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))",
"v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus)",
"mycl proto-oncogene, bhlh transcription factor (homo sapiens)",
"c-myc-binding protein homolog (glycine max)"
] | Given the context 'Here we show that Yaf2 also binds to the Myc protein in vivo and in vitro.', answer the user's query. |
What is the biomedical concept corresponding to 'mycn'? | [
"mycn proto-oncogene, bhlh transcription factor (homo sapiens)",
"mycn (homo sapiens)",
"n-myc (homo sapiens)"
] | [
"mycn (mus musculus)",
"v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus)",
"mycn, opposite strand (mus musculus)",
"mycn proto-oncogene, bhlh transcription factor (xenopus tropicalis)"
] | Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', answer the user's query. |
What is the biomedical concept corresponding to 'yaf2'? | [
"yaf2 (homo sapiens)"
] | [
"yaf1 (homo sapiens)",
"yaf2 (xenopus tropicalis)",
"yaf1 (saccharomyces cerevisiae s288c)",
"yaf2-b (xenopus laevis) (yy1 associated factor 2 s homeolog (xenopus laevis))"
] | Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', answer the user's query. |
What is the biomedical concept corresponding to 'myc'? | [
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (homo sapiens)",
"c-myc (homo sapiens)"
] | [
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))",
"v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus)",
"mycl proto-oncogene, bhlh transcription factor (homo sapiens)",
"c-myc-binding protein homolog (glycine max)"
] | Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', answer the user's query. |
What is the biomedical concept corresponding to 'myc'? | [
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (homo sapiens)",
"c-myc (homo sapiens)"
] | [
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))",
"v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus)",
"mycl proto-oncogene, bhlh transcription factor (homo sapiens)",
"c-myc-binding protein homolog (glycine max)"
] | Given the context 'This differential influence on two members of the Myc family gives insight into a new mechanism to modulate the biological activities of Myc transcription factors.', answer the user's query. |
What is the biomedical concept corresponding to 'myc'? | [
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (homo sapiens)",
"c-myc (homo sapiens)"
] | [
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))",
"v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus)",
"mycl proto-oncogene, bhlh transcription factor (homo sapiens)",
"c-myc-binding protein homolog (glycine max)"
] | Given the context 'This differential influence on two members of the Myc family gives insight into a new mechanism to modulate the biological activities of Myc transcription factors.', answer the user's query. |
What is the biomedical concept corresponding to 'keratinocyte growth factor receptor'? | [
"kgfr (homo sapiens)",
"fgfr2 (homo sapiens)",
"fibroblast growth factor receptor 2 (homo sapiens)"
] | [
"bfgfr (homo sapiens)",
"fgfbr (homo sapiens)",
"fibroblast growth factor receptor 1 (homo sapiens)",
"fibroblast growth factor receptor 3 (homo sapiens)"
] | Given the context 'Bacteria expressing the kinase domain of the keratinocyte growth factor receptor (bek/fibroblast growth factor receptor 2) were infected with a fibroblast cDNA library in a phagemid prokaryotic expression vector and screened with a monoclonal anti-phosphotyrosine antibody.', answer the user's query. |
What is the biomedical concept corresponding to 'bek'? | [
"bek (homo sapiens)"
] | [
"bek (xenopus tropicalis)",
"bek (mus musculus)",
"ekb (homo sapiens)",
"rabepk (bos taurus)"
] | Given the context 'Bacteria expressing the kinase domain of the keratinocyte growth factor receptor (bek/fibroblast growth factor receptor 2) were infected with a fibroblast cDNA library in a phagemid prokaryotic expression vector and screened with a monoclonal anti-phosphotyrosine antibody.', answer the user's query. |
What is the biomedical concept corresponding to 'fibroblast growth factor receptor 2'? | [
"fibroblast growth factor receptor 2 (homo sapiens)",
"fgfr2 (homo sapiens)"
] | [
"fibroblast growth factor receptor 3 (homo sapiens)",
"fgfbr (homo sapiens)",
"flt-2 (homo sapiens)",
"flt2 (homo sapiens)"
] | Given the context 'Bacteria expressing the kinase domain of the keratinocyte growth factor receptor (bek/fibroblast growth factor receptor 2) were infected with a fibroblast cDNA library in a phagemid prokaryotic expression vector and screened with a monoclonal anti-phosphotyrosine antibody.', answer the user's query. |
What is the biomedical concept corresponding to 'vh1-related (vhr) human protein'? | [
"vhr (homo sapiens)"
] | [
"vhp (homo sapiens)",
"vh5 (homo sapiens)",
"vhx (homo sapiens)",
"hshvrp1 (homo sapiens)"
] | Given the context 'Both serine and tyrosine phosphatase activities were completely abolished by mutagenesis of a single cysteine residue conserved in VH1 and the VH1-related (VHR) human protein.', answer the user's query. |
What is the biomedical concept corresponding to 'vhr'? | [
"vhr (homo sapiens)"
] | [
"vhr (mus musculus)",
"vhr1 (saccharomyces cerevisiae s288c)",
"vhr1p (saccharomyces cerevisiae s288c)",
"vho (homo sapiens)"
] | Given the context 'These properties suggest that VHR is capable of regulating intracellular events mediated by both tyrosine and serine phosphorylation.', answer the user's query. |
What is the biomedical concept corresponding to 'ah receptor nuclear translocator'? | [
"aryl hydrocarbon receptor nuclear translocator (homo sapiens)",
"arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens))",
"arnt1 (homo sapiens)",
"tango (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens))"
] | [
"aryl hydrocarbon receptor nuclear translocator homolog (caenorhabditis elegans)",
"aryl hydrocarbon receptor nuclear translocator (rattus norvegicus)",
"aryl hydrocarbon receptor nuclear translocator (xenopus tropicalis)",
"aryl hydrocarbon receptor (homo sapiens)"
] | Given the context 'Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
', answer the user's query. |
What is the biomedical concept corresponding to 'arnt'? | [
"arnt1 (homo sapiens)",
"arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens))"
] | [
"arnt (drosophila melanogaster)",
"arno (homo sapiens)",
"arntl (homo sapiens)",
"basic helix-loop-helix arnt like 1 (homo sapiens)"
] | Given the context 'Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
', answer the user's query. |
What is the biomedical concept corresponding to 'ah receptor'? | [
"aryl hydrocarbon receptor (homo sapiens)",
"ahr (homo sapiens)"
] | [
"ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens))",
"ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens))",
"ahh (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens))",
"aryl hydrocarbon receptor (rattus norvegicus)"
] | Given the context 'Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
', answer the user's query. |
What is the biomedical concept corresponding to 'ah (dioxin) receptor'? | [
"aryl hydrocarbon receptor (homo sapiens)",
"ahr (homo sapiens)"
] | [
"ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens))",
"ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens))",
"aryl hydrocarbon receptor nuclear translocator homolog (caenorhabditis elegans)",
"aryl hydrocarbon receptor 1a (danio rerio)"
] | Given the context 'The Ah (dioxin) receptor binds a number of widely disseminated environmental pollutants, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and polycyclic aromatic hydrocarbons, and mediates their carcinogenic effects.', answer the user's query. |
What is the biomedical concept corresponding to 'cyp 1a1'? | [
"cytochrome p450 family 1 subfamily a member 1 (homo sapiens)",
"cyp1 (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens))",
"ahh (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens))"
] | [
"cyp1alpha (homo sapiens)",
"1a1 (homo sapiens)",
"cytochrome p450 1a1 (oryctolagus cuniculus)",
"cytochrome p450 family 1 subfamily b member 1 (homo sapiens)"
] | Given the context 'The ligand-bound receptor activates Cyp 1a1 gene transcription through interaction with specific DNA sequences, termed xenobiotic responsive elements (XREs).', answer the user's query. |
What is the biomedical concept corresponding to 'ah receptor nuclear translocator'? | [
"aryl hydrocarbon receptor nuclear translocator (homo sapiens)",
"arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens))",
"arnt1 (homo sapiens)",
"tango (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens))"
] | [
"aryl hydrocarbon receptor nuclear translocator homolog (caenorhabditis elegans)",
"aryl hydrocarbon receptor nuclear translocator (rattus norvegicus)",
"aryl hydrocarbon receptor nuclear translocator (xenopus tropicalis)",
"aryl hydrocarbon receptor (homo sapiens)"
] | Given the context 'The Ah receptor nuclear translocator protein (Arnt) is required for Ah receptor function.', answer the user's query. |
What is the biomedical concept corresponding to 'arnt'? | [
"arnt1 (homo sapiens)",
"arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens))"
] | [
"arnt (drosophila melanogaster)",
"arno (homo sapiens)",
"arntl (homo sapiens)",
"basic helix-loop-helix arnt like 1 (homo sapiens)"
] | Given the context 'The Ah receptor nuclear translocator protein (Arnt) is required for Ah receptor function.', answer the user's query. |
What is the biomedical concept corresponding to 'ah receptor'? | [
"aryl hydrocarbon receptor (homo sapiens)",
"ahr (homo sapiens)"
] | [
"ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens))",
"ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens))",
"ahh (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens))",
"aryl hydrocarbon receptor (rattus norvegicus)"
] | Given the context 'The Ah receptor nuclear translocator protein (Arnt) is required for Ah receptor function.', answer the user's query. |
What is the biomedical concept corresponding to 'arnt'? | [
"arnt1 (homo sapiens)",
"arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens))"
] | [
"arnt (drosophila melanogaster)",
"arno (homo sapiens)",
"arntl (homo sapiens)",
"basic helix-loop-helix arnt like 1 (homo sapiens)"
] | Given the context 'Arnt is now shown to be a structural component of the XRE binding form of the Ah receptor.', answer the user's query. |
What is the biomedical concept corresponding to 'ah receptor'? | [
"aryl hydrocarbon receptor (homo sapiens)",
"ahr (homo sapiens)"
] | [
"ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens))",
"ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens))",
"ahh (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens))",
"aryl hydrocarbon receptor (rattus norvegicus)"
] | Given the context 'Arnt is now shown to be a structural component of the XRE binding form of the Ah receptor.', answer the user's query. |
What is the biomedical concept corresponding to 'arnt'? | [
"arnt1 (homo sapiens)",
"arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens))"
] | [
"arnt (drosophila melanogaster)",
"arno (homo sapiens)",
"arntl (homo sapiens)",
"basic helix-loop-helix arnt like 1 (homo sapiens)"
] | Given the context 'Furthermore, Arnt and the ligand-binding subunit of the receptor were extracted as a complex from the nuclei of cells treated with ligand.', answer the user's query. |
What is the biomedical concept corresponding to 'arnt'? | [
"arnt1 (homo sapiens)",
"arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens))"
] | [
"arnt (drosophila melanogaster)",
"arno (homo sapiens)",
"arntl (homo sapiens)",
"basic helix-loop-helix arnt like 1 (homo sapiens)"
] | Given the context 'Arnt contains a basic helix-loop-helix motif, which may be responsible for interacting with both the XRE and the ligand-binding subunit.', answer the user's query. |
What is the biomedical concept corresponding to 'saf-a'? | [
"saf-a (homo sapiens)",
"safa (homo sapiens)"
] | [
"saf-a (xenopus tropicalis)",
"saf-1 (homo sapiens)",
"saf-b (homo sapiens)",
"scf ubiquitin ligase complex subunit saf1 (saccharomyces cerevisiae s288c)"
] | Given the context 'Characterization of SAF-A, a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements.
', answer the user's query. |
What is the biomedical concept corresponding to 'saf-a'? | [
"saf-a (homo sapiens)",
"safa (homo sapiens)"
] | [
"saf-a (xenopus tropicalis)",
"saf-1 (homo sapiens)",
"saf-b (homo sapiens)",
"scf ubiquitin ligase complex subunit saf1 (saccharomyces cerevisiae s288c)"
] | Given the context 'Of these four proteins, SAF-A (scaffold attachment factor A), shows the highest affinity for several homologous and heterologous SAR elements from vertebrate cells.', answer the user's query. |
What is the biomedical concept corresponding to 'scaffold attachment factor a'? | [
"saf-a (homo sapiens)",
"safa (homo sapiens)"
] | [
"saf-a (xenopus tropicalis)",
"uv-stimulated scaffold protein a homolog (caenorhabditis elegans)",
"uv stimulated scaffold protein a (xenopus tropicalis)",
"scaffold attachment factor b (xenopus tropicalis)"
] | Given the context 'Of these four proteins, SAF-A (scaffold attachment factor A), shows the highest affinity for several homologous and heterologous SAR elements from vertebrate cells.', answer the user's query. |
What is the biomedical concept corresponding to 'saf-a'? | [
"saf-a (homo sapiens)",
"safa (homo sapiens)"
] | [
"saf-a (xenopus tropicalis)",
"saf-1 (homo sapiens)",
"saf-b (homo sapiens)",
"scf ubiquitin ligase complex subunit saf1 (saccharomyces cerevisiae s288c)"
] | Given the context 'SAF-A is an abundant nuclear protein and a constituent of the nuclear matrix and scaffold.', answer the user's query. |
What is the biomedical concept corresponding to 'saf-a'? | [
"saf-a (homo sapiens)",
"safa (homo sapiens)"
] | [
"saf-a (xenopus tropicalis)",
"saf-1 (homo sapiens)",
"saf-b (homo sapiens)",
"scf ubiquitin ligase complex subunit saf1 (saccharomyces cerevisiae s288c)"
] | Given the context 'SAF-A binds at multiple sites to the human SAR element; competition studies with synthetic polynucleotides indicate that these sites most probably reside in the multitude of A/T-stretches which are distributed throughout this element.', answer the user's query. |
What is the biomedical concept corresponding to 'udp-glcnac:gal beta 1-3-galnac-r (glcnac to galnac) beta 1-6glcnac transferase'? | [
"c2glcnact (homo sapiens)",
"c2gnt-l (homo sapiens)"
] | [
"galnt6 (homo sapiens)",
"galnt3 (homo sapiens)",
"galnt1 (homo sapiens)",
"provisional ortholog of core 1 synthase, glycoprotein-n-acetylgalactosamine 3-beta-galactosyltransferase 1 (xenopus tropicalis)"
] | Given the context 'Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen.
', answer the user's query. |
What is the biomedical concept corresponding to 'udp-glcnac:gal beta 1-3galnac-r (glcnac to galnac) beta 1-6glcnac transferase'? | [
"c2glcnact (homo sapiens)",
"c2gnt-l (homo sapiens)",
"c2gnt (homo sapiens)"
] | [
"galnt6 (homo sapiens)",
"galnt1 (homo sapiens)",
"galnt2 (homo sapiens)",
"galnt3 (homo sapiens)"
] | Given the context 'A cDNA encoding UDP-GlcNAc:Gal beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase (EC 2.4.1.102), which forms critical branches in O-glycans, has been isolated by an expression cloning approach using Chinese hamster ovary (CHO) cells.', answer the user's query. |
What is the biomedical concept corresponding to 'leukosialin'? | [
"sialophorin (homo sapiens)",
"spn (homo sapiens) (sialophorin (homo sapiens))"
] | [
"leukosialin-like (rattus norvegicus)",
"sialin (homo sapiens)",
"sialophorin (bos taurus)",
"sialophorin (sus scrofa)"
] | Given the context 'Because the antibody used was found to detect most efficiently the oligosaccharide products attached to leukosialin, the CHO cells were also stably transfected with leukosialin cDNA.', answer the user's query. |
What is the biomedical concept corresponding to 'leukosialin'? | [
"sialophorin (homo sapiens)",
"spn (homo sapiens) (sialophorin (homo sapiens))"
] | [
"leukosialin-like (rattus norvegicus)",
"sialin (homo sapiens)",
"sialophorin (bos taurus)",
"sialophorin (sus scrofa)"
] | Given the context 'Because the antibody used was found to detect most efficiently the oligosaccharide products attached to leukosialin, the CHO cells were also stably transfected with leukosialin cDNA.', answer the user's query. |
What is the biomedical concept corresponding to 'core 2 beta-1,6-n-acetylglucosaminyltransferase'? | [
"c2glcnact (homo sapiens)",
"c2gnt (homo sapiens)",
"c2gnt-l (homo sapiens)"
] | [
"core-2/i-branching beta-1,6-n-acetylglucosaminyltransferase family protein (caenorhabditis elegans)",
"alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase (homo sapiens)",
"b3gnt1, beta-1,3-n-acetylgucosaminyltransferase 1, homolog;glyco_trans_2-like domain-containing protein (caenorhabditis... | Given the context 'The expression of the presumed catalytic domain as a fusion protein with the IgG binding domain of protein A enabled us to demonstrate unequivocally that the cDNA encodes the core 2 beta-1,6-N-acetylglucosaminyltransferase, the enzyme responsible for the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures.', answer the user's query. |
What is the biomedical concept corresponding to 'tumor necrosis factor-alpha'? | [
"tnfa (homo sapiens)",
"tumor necrosis factor (homo sapiens)",
"tnf (homo sapiens)"
] | [
"lymphotoxin alpha (homo sapiens)",
"tnfc (homo sapiens)",
"tumor necrosis factor (xenopus tropicalis)",
"tnfb (homo sapiens)"
] | Given the context 'Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro.
TNF is a proinflammatory cytokine that has pleiotropic effects on cells and tissues, mediated in large part by alterations in target tissue gene expression.', answer the user's query. |
What is the biomedical concept corresponding to 'tnf'? | [
"tnf (homo sapiens)",
"tumor necrosis factor (homo sapiens)",
"tnfa (homo sapiens)"
] | [
"lymphotoxin alpha (homo sapiens)",
"tnfb (homo sapiens)",
"tnfsf1 (homo sapiens)",
"tnf superfamily member 10 (homo sapiens)"
] | Given the context 'Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro.
TNF is a proinflammatory cytokine that has pleiotropic effects on cells and tissues, mediated in large part by alterations in target tissue gene expression.', answer the user's query. |
What is the biomedical concept corresponding to 'tnf'? | [
"tnf (homo sapiens)",
"tumor necrosis factor (homo sapiens)",
"tnfa (homo sapiens)"
] | [
"lymphotoxin alpha (homo sapiens)",
"tnfb (homo sapiens)",
"tnfsf1 (homo sapiens)",
"tnf superfamily member 10 (homo sapiens)"
] | Given the context 'We have used the technique of differential hybridization to identify several primary response genes induced by TNF in human umbilical vein endothelial (HUVE) cells, a cell type that is profoundly activated by cytokine treatment.', answer the user's query. |
What is the biomedical concept corresponding to 'b94'? | [
"b94 (homo sapiens)"
] | [
"b94 (mus musculus)",
"hg94 (homo sapiens)",
"p94 (homo sapiens)",
"rp94 (homo sapiens)"
] | Given the context 'One of these cDNA, designated B94, detects a rapidly and transiently induced 4-kb transcript in TNF-treated HUVE cells, and this transcript is superinduced in the concomitant presence of cycloheximide.', answer the user's query. |
What is the biomedical concept corresponding to 'tnf'? | [
"tnf (homo sapiens)",
"tumor necrosis factor (homo sapiens)",
"tnfa (homo sapiens)"
] | [
"lymphotoxin alpha (homo sapiens)",
"tnfb (homo sapiens)",
"tnfsf1 (homo sapiens)",
"tnf superfamily member 10 (homo sapiens)"
] | Given the context 'One of these cDNA, designated B94, detects a rapidly and transiently induced 4-kb transcript in TNF-treated HUVE cells, and this transcript is superinduced in the concomitant presence of cycloheximide.', answer the user's query. |
What is the biomedical concept corresponding to 'il-1 beta'? | [
"interleukin 1 beta (homo sapiens)",
"il1-beta (homo sapiens)",
"il1beta (homo sapiens)",
"il1b (homo sapiens)",
"il-1 (homo sapiens)"
] | [
"interferon beta 1 (homo sapiens)",
"ifn-beta (homo sapiens)",
"interleukin 36 beta (homo sapiens)",
"ifnb1 (homo sapiens)"
] | Given the context 'Other proinflammatory stimuli including IL-1 beta and LPS are also able to induce B94 mRNA expression.', answer the user's query. |
What is the biomedical concept corresponding to 'b94'? | [
"b94 (homo sapiens)"
] | [
"b94 (mus musculus)",
"hg94 (homo sapiens)",
"p94 (homo sapiens)",
"rp94 (homo sapiens)"
] | Given the context 'Other proinflammatory stimuli including IL-1 beta and LPS are also able to induce B94 mRNA expression.', answer the user's query. |
What is the biomedical concept corresponding to 'tnf'? | [
"tnf (homo sapiens)",
"tumor necrosis factor (homo sapiens)",
"tnfa (homo sapiens)"
] | [
"lymphotoxin alpha (homo sapiens)",
"tnfb (homo sapiens)",
"tnfsf1 (homo sapiens)",
"tnf superfamily member 10 (homo sapiens)"
] | Given the context 'Nuclear run-on experiments demonstrate that TNF induction of B94 transcript occurs primarily at the level of transcriptional activation.', answer the user's query. |
What is the biomedical concept corresponding to 'b94'? | [
"b94 (homo sapiens)"
] | [
"b94 (mus musculus)",
"hg94 (homo sapiens)",
"p94 (homo sapiens)",
"rp94 (homo sapiens)"
] | Given the context 'Nuclear run-on experiments demonstrate that TNF induction of B94 transcript occurs primarily at the level of transcriptional activation.', answer the user's query. |
What is the biomedical concept corresponding to 'b94'? | [
"b94 (homo sapiens)"
] | [
"b94 (mus musculus)",
"hg94 (homo sapiens)",
"p94 (homo sapiens)",
"rp94 (homo sapiens)"
] | Given the context 'Further, B94 is shown to be a single copy gene that is evolutionarily conserved.', answer the user's query. |
What is the biomedical concept corresponding to 'b94'? | [
"b94 (homo sapiens)"
] | [
"b94 (mus musculus)",
"hg94 (homo sapiens)",
"p94 (homo sapiens)",
"rp94 (homo sapiens)"
] | Given the context 'Developmental regulation occurs most prominently in mouse embryonic liver and kidney, and a second smaller form of B94 transcript is detected in the placenta and testes.', answer the user's query. |
What is the biomedical concept corresponding to 'b94'? | [
"b94 (homo sapiens)"
] | [
"b94 (mus musculus)",
"hg94 (homo sapiens)",
"p94 (homo sapiens)",
"rp94 (homo sapiens)"
] | Given the context 'B94 and other TNF-responsive transcripts are also induced during capillary tube formation suggesting overlap between genes induced by TNF and those induced during angiogenesis.', answer the user's query. |
What is the biomedical concept corresponding to 'tnf'? | [
"tnf (homo sapiens)",
"tumor necrosis factor (homo sapiens)",
"tnfa (homo sapiens)"
] | [
"lymphotoxin alpha (homo sapiens)",
"tnfb (homo sapiens)",
"tnfsf1 (homo sapiens)",
"tnf superfamily member 10 (homo sapiens)"
] | Given the context 'B94 and other TNF-responsive transcripts are also induced during capillary tube formation suggesting overlap between genes induced by TNF and those induced during angiogenesis.', answer the user's query. |
What is the biomedical concept corresponding to 'tnf'? | [
"tnf (homo sapiens)",
"tumor necrosis factor (homo sapiens)",
"tnfa (homo sapiens)"
] | [
"lymphotoxin alpha (homo sapiens)",
"tnfb (homo sapiens)",
"tnfsf1 (homo sapiens)",
"tnf superfamily member 10 (homo sapiens)"
] | Given the context 'B94 and other TNF-responsive transcripts are also induced during capillary tube formation suggesting overlap between genes induced by TNF and those induced during angiogenesis.', answer the user's query. |
What is the biomedical concept corresponding to 'b94'? | [
"b94 (homo sapiens)"
] | [
"b94 (mus musculus)",
"hg94 (homo sapiens)",
"p94 (homo sapiens)",
"rp94 (homo sapiens)"
] | Given the context 'Sequence analysis of the B94 cDNA reveals an open reading frame encoding a 73-kDa polypeptide that has no homology to any known protein.', answer the user's query. |
What is the biomedical concept corresponding to 'b94'? | [
"b94 (homo sapiens)"
] | [
"b94 (mus musculus)",
"hg94 (homo sapiens)",
"p94 (homo sapiens)",
"rp94 (homo sapiens)"
] | Given the context 'Polyclonal antisera directed against the carboxyl-terminal portion of the B94 protein immunoprecipitates a protein of the predicted molecular mass both from COS cells transfected with a B94 expression vector and from TNF-treated HUVE cells.', answer the user's query. |
What is the biomedical concept corresponding to 'b94'? | [
"b94 (homo sapiens)"
] | [
"b94 (mus musculus)",
"hg94 (homo sapiens)",
"p94 (homo sapiens)",
"rp94 (homo sapiens)"
] | Given the context 'Polyclonal antisera directed against the carboxyl-terminal portion of the B94 protein immunoprecipitates a protein of the predicted molecular mass both from COS cells transfected with a B94 expression vector and from TNF-treated HUVE cells.', answer the user's query. |
What is the biomedical concept corresponding to 'tnf'? | [
"tnf (homo sapiens)",
"tumor necrosis factor (homo sapiens)",
"tnfa (homo sapiens)"
] | [
"lymphotoxin alpha (homo sapiens)",
"tnfb (homo sapiens)",
"tnfsf1 (homo sapiens)",
"tnf superfamily member 10 (homo sapiens)"
] | Given the context 'Polyclonal antisera directed against the carboxyl-terminal portion of the B94 protein immunoprecipitates a protein of the predicted molecular mass both from COS cells transfected with a B94 expression vector and from TNF-treated HUVE cells.', answer the user's query. |
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