instruction stringlengths 226 748 | input stringlengths 159 2.15k | response stringlengths 3 12 |
|---|---|---|
<Instruct>: Given the context 'However, hMre11B does not interact with Mre11, Rad50 and Xrs2.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hmre11b; mre11; rad50; xrs2]
<Options>: A: mre11 homolog, double strand break repair nuclease (gallus gallus) (aka mre11 homolog, double strand break repair nuclease)
B: xrn2 (homo sapiens) (aka 5'-3' exoribonuclease 2)
C: or4c11b (mus musculus) (aka olfactory receptor family 4 subfamily c member 11b)
D: mre11 (drosophila melanogaster) (igf-ii mrna-binding protein (drosophila melanogaster)) (aka igf-ii mrna-binding protein)
E: xrs2p (saccharomyces cerevisiae s288c) (aka xrs2p)
F: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
G: hsd11b (homo sapiens) (aka hydroxysteroid 11-beta dehydrogenase 1)
H: rad50 (xenopus tropicalis) (aka rad50 homolog, double strand break repair protein)
I: rad50 (xenopus laevis) (aka rad50 homolog, double strand break repair protein l homeolog)
J: mre11 (mus musculus) (aka mre11a homolog a, double strand break repair nuclease)
K: or2h1b (mus musculus) (aka olfactory receptor family 2 subfamily h member 1b)
L: rad-50 (drosophila melanogaster) (aka rad50)
M: xrn2 (saccharomyces cerevisiae s288c) (aka ssrna exonuclease rat1)
N: xrg2 (homo sapiens) (aka xk related x-linked)
O: xrp2 (homo sapiens) (aka rp2 activator of arl3 gtpase)
P: rad50 (saccharomyces cerevisiae s288c) (aka mrx complex dna-binding subunit)
Q: dna repair protein rad50-like (xenopus tropicalis) (aka dna repair protein rad50-like)
R: mre11 (drosophila melanogaster) (meiotic recombination 11 (drosophila melanogaster)) (aka meiotic recombination 11)
S: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
T: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
U: None of the above. | [T; U; P; E] |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hmre11b; mre11; rad50; xrs2]
<Options>: A: xrn2 (homo sapiens) (aka 5'-3' exoribonuclease 2)
B: rad-50 (drosophila melanogaster) (aka rad50)
C: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
D: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
E: dna repair protein xrcc2-like (xenopus tropicalis) (aka dna repair protein xrcc2-like)
F: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
G: xrg2 (homo sapiens) (aka xk related x-linked)
H: xrs2p (saccharomyces cerevisiae s288c) (aka xrs2p)
I: mre11 (homo sapiens) (aka mre11 double strand break repair nuclease)
J: rad50 (xenopus tropicalis) (aka rad50 homolog, double strand break repair protein)
K: or4c11b (mus musculus) (aka olfactory receptor family 4 subfamily c member 11b)
L: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
M: or2h1b (mus musculus) (aka olfactory receptor family 2 subfamily h member 1b)
N: dna repair protein rad50-like (xenopus tropicalis) (aka dna repair protein rad50-like)
O: mre11 (drosophila melanogaster) (igf-ii mrna-binding protein (drosophila melanogaster)) (aka igf-ii mrna-binding protein)
P: rad50 (saccharomyces cerevisiae s288c) (aka mrx complex dna-binding subunit)
Q: x-ray repair cross complementing 2 (drosophila melanogaster) (aka x-ray repair cross complementing 2)
R: rad50 (xenopus laevis) (aka rad50 homolog, double strand break repair protein l homeolog)
S: hsd11b (homo sapiens) (aka hydroxysteroid 11-beta dehydrogenase 1)
T: mre11 homolog, double strand break repair nuclease (gallus gallus) (aka mre11 homolog, double strand break repair nuclease)
U: None of the above. | [C; U; P; H] |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hmre11b; mre11; rad50; xrs2]
<Options>: A: dna repair protein xrcc2-like (xenopus tropicalis) (aka dna repair protein xrcc2-like)
B: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
C: xrn2 (saccharomyces cerevisiae s288c) (aka ssrna exonuclease rat1)
D: or4c11b (mus musculus) (aka olfactory receptor family 4 subfamily c member 11b)
E: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
F: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
G: rad50 homolog, double strand break repair protein (xenopus tropicalis) (aka rad50 homolog, double strand break repair protein)
H: mre11 (mus musculus) (aka mre11a homolog a, double strand break repair nuclease)
I: dna repair protein rad50-like (xenopus tropicalis) (aka dna repair protein rad50-like)
J: rad50 (drosophila melanogaster) (aka rad50)
K: xrg2 (homo sapiens) (aka xk related x-linked)
L: xrs2 (saccharomyces cerevisiae s288c) (aka xrs2p)
M: mre11 (drosophila melanogaster) (igf-ii mrna-binding protein (drosophila melanogaster)) (aka igf-ii mrna-binding protein)
N: olfactory receptor family 11 subfamily h member 12b (bos taurus) (aka olfactory receptor family 11 subfamily h member 12b)
O: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
P: olfactory receptor family 11 subfamily h member 4b (mus musculus) (aka olfactory receptor family 11 subfamily h member 4b)
Q: xrn2 (homo sapiens) (aka 5'-3' exoribonuclease 2)
R: mre11 homolog, double strand break repair nuclease (gallus gallus) (aka mre11 homolog, double strand break repair nuclease)
S: rad50 (xenopus laevis) (aka rad50 homolog, double strand break repair protein l homeolog)
T: rad50 (saccharomyces cerevisiae s288c) (aka mrx complex dna-binding subunit)
U: None of the above. | [F; U; T; L] |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hmre11b; mre11; rad50; xrs2]
<Options>: A: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
B: rad50 (xenopus laevis) (aka rad50 homolog, double strand break repair protein l homeolog)
C: olfactory receptor family 11 subfamily h member 12b (bos taurus) (aka olfactory receptor family 11 subfamily h member 12b)
D: mre11 homolog, double strand break repair nuclease (rattus norvegicus) (aka mre11 homolog, double strand break repair nuclease)
E: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
F: mre11 double strand break repair nuclease (homo sapiens) (aka mre11 double strand break repair nuclease)
G: dna repair protein rad50-like (xenopus tropicalis) (aka dna repair protein rad50-like)
H: x-ray repair cross complementing 2 (drosophila melanogaster) (aka x-ray repair cross complementing 2)
I: dna repair protein xrcc2-like (xenopus tropicalis) (aka dna repair protein xrcc2-like)
J: mre11 (drosophila melanogaster) (meiotic recombination 11 (drosophila melanogaster)) (aka meiotic recombination 11)
K: xrn2 (saccharomyces cerevisiae s288c) (aka ssrna exonuclease rat1)
L: rad50 (homo sapiens) (aka rad50 double strand break repair protein)
M: or2h1b (mus musculus) (aka olfactory receptor family 2 subfamily h member 1b)
N: xrg2 (homo sapiens) (aka xk related x-linked)
O: rad50 (saccharomyces cerevisiae s288c) (aka mrx complex dna-binding subunit)
P: olfactory receptor family 8 subfamily b member 12b (mus musculus) (aka olfactory receptor family 8 subfamily b member 12b)
Q: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
R: rad50 homolog, double strand break repair protein (xenopus tropicalis) (aka rad50 homolog, double strand break repair protein)
S: or9m1b (mus musculus) (aka olfactory receptor family 9 subfamily m member 1b)
T: xrs2 (saccharomyces cerevisiae s288c) (aka xrs2p)
U: None of the above. | [E; U; O; T] |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hmre11b; mre11; rad50; xrs2]
<Options>: A: or4c11b (mus musculus) (aka olfactory receptor family 4 subfamily c member 11b)
B: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
C: rad50 homolog, double strand break repair protein (xenopus tropicalis) (aka rad50 homolog, double strand break repair protein)
D: olfactory receptor family 11 subfamily h member 4b (mus musculus) (aka olfactory receptor family 11 subfamily h member 4b)
E: dna repair protein xrcc2-like (xenopus tropicalis) (aka dna repair protein xrcc2-like)
F: xrs2p (saccharomyces cerevisiae s288c) (aka xrs2p)
G: rad-50 (drosophila melanogaster) (aka rad50)
H: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
I: xrg2 (homo sapiens) (aka xk related x-linked)
J: olfactory receptor family 11 subfamily h member 12b (bos taurus) (aka olfactory receptor family 11 subfamily h member 12b)
K: dna repair protein rad50-like (xenopus tropicalis) (aka dna repair protein rad50-like)
L: mre11 (drosophila melanogaster) (meiotic recombination 11 (drosophila melanogaster)) (aka meiotic recombination 11)
M: hrad50 (homo sapiens) (aka rad50 double strand break repair protein)
N: xrn2 (saccharomyces cerevisiae s288c) (aka ssrna exonuclease rat1)
O: x-ray repair cross complementing 2 (homo sapiens) (aka x-ray repair cross complementing 2)
P: mre11 (homo sapiens) (aka mre11 double strand break repair nuclease)
Q: rad50 (saccharomyces cerevisiae s288c) (aka mrx complex dna-binding subunit)
R: hsd11b (homo sapiens) (aka hydroxysteroid 11-beta dehydrogenase 1)
S: mre11 homolog, double strand break repair nuclease (gallus gallus) (aka mre11 homolog, double strand break repair nuclease)
T: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
U: None of the above. | [H; U; Q; F] |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hmre11b; mre11]
<Options>: A: mre11 (mus musculus) (aka mre11a homolog a, double strand break repair nuclease)
B: or2h1b (mus musculus) (aka olfactory receptor family 2 subfamily h member 1b)
C: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
D: mre11 (homo sapiens) (aka mre11 double strand break repair nuclease)
E: mre11 (drosophila melanogaster) (meiotic recombination 11 (drosophila melanogaster)) (aka meiotic recombination 11)
F: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
G: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
H: olfactory receptor family 11 subfamily h member 12b (bos taurus) (aka olfactory receptor family 11 subfamily h member 12b)
I: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
J: or9m1b (mus musculus) (aka olfactory receptor family 9 subfamily m member 1b)
K: None of the above. | [F; K] |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hmre11b; mre11]
<Options>: A: mre11 homolog, double strand break repair nuclease (gallus gallus) (aka mre11 homolog, double strand break repair nuclease)
B: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
C: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
D: mre11 (drosophila melanogaster) (igf-ii mrna-binding protein (drosophila melanogaster)) (aka igf-ii mrna-binding protein)
E: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
F: or4c11b (mus musculus) (aka olfactory receptor family 4 subfamily c member 11b)
G: mre11 double strand break repair nuclease (homo sapiens) (aka mre11 double strand break repair nuclease)
H: or2h1b (mus musculus) (aka olfactory receptor family 2 subfamily h member 1b)
I: mre11 (drosophila melanogaster) (meiotic recombination 11 (drosophila melanogaster)) (aka meiotic recombination 11)
J: or11h4b (mus musculus) (aka olfactory receptor family 11 subfamily h member 4b)
K: None of the above. | [E; K] |
<Instruct>: Given the context 'We rule out the hypothesis that the lack of interaction and, in turn of complementation, is due to the absence of sequence homology at the C-terminal domain of hMre11B compared to the yeast Mre11.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hmre11b; mre11]
<Options>: A: or2h1b (mus musculus) (aka olfactory receptor family 2 subfamily h member 1b)
B: mre11 (drosophila melanogaster) (meiotic recombination 11 (drosophila melanogaster)) (aka meiotic recombination 11)
C: or9m1b (mus musculus) (aka olfactory receptor family 9 subfamily m member 1b)
D: olfactory receptor family 8 subfamily b member 12b (mus musculus) (aka olfactory receptor family 8 subfamily b member 12b)
E: mre11a homolog a, double strand break repair nuclease (mus musculus) (aka mre11a homolog a, double strand break repair nuclease)
F: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
G: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
H: mre11 (homo sapiens) (aka mre11 double strand break repair nuclease)
I: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
J: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
K: None of the above. | [F; K] |
<Instruct>: Given the context 'We rule out the hypothesis that the lack of interaction and, in turn of complementation, is due to the absence of sequence homology at the C-terminal domain of hMre11B compared to the yeast Mre11.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hmre11b; mre11]
<Options>: A: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
B: olfactory receptor family 11 subfamily h member 12b (bos taurus) (aka olfactory receptor family 11 subfamily h member 12b)
C: mre11 homolog, double strand break repair nuclease (rattus norvegicus) (aka mre11 homolog, double strand break repair nuclease)
D: olfactory receptor family 8 subfamily b member 12b (mus musculus) (aka olfactory receptor family 8 subfamily b member 12b)
E: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
F: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
G: mre11 homolog, double strand break repair nuclease (gallus gallus) (aka mre11 homolog, double strand break repair nuclease)
H: mre11 (drosophila melanogaster) (igf-ii mrna-binding protein (drosophila melanogaster)) (aka igf-ii mrna-binding protein)
I: or2h1b (mus musculus) (aka olfactory receptor family 2 subfamily h member 1b)
J: mre11a homolog a, double strand break repair nuclease (mus musculus) (aka mre11a homolog a, double strand break repair nuclease)
K: None of the above. | [A; K] |
<Instruct>: Given the context 'Instead, we propose that the C-terminus of hMre11B participates in protein-protein interaction and functions in a species-specific manner.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [hmre11b]
<Options>: A: or4c11b (mus musculus) (aka olfactory receptor family 4 subfamily c member 11b)
B: or9m1b (mus musculus) (aka olfactory receptor family 9 subfamily m member 1b)
C: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
D: hsd11b (homo sapiens) (aka hydroxysteroid 11-beta dehydrogenase 1)
E: or2h1b (mus musculus) (aka olfactory receptor family 2 subfamily h member 1b)
F: None of the above. | [C] |
<Instruct>: Given the context 'XCE, a new member of the endothelin-converting enzyme and neutral endopeptidase family, is preferentially expressed in the CNS.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [xce]
<Options>: A: xct (homo sapiens) (aka solute carrier family 7 member 11)
B: xcxcra (xenopus laevis) (aka c-x-c chemokine receptor type a)
C: xce (homo sapiens) (x chromosome inactivation center (homo sapiens)) (aka x chromosome inactivation center)
D: xce (homo sapiens) (x chromosome controlling element (homo sapiens)) (aka x chromosome controlling element)
E: xcel (xenopus tropicalis) (aka carboxyl ester lipase, gene 2)
F: None of the above. | [F] |
<Instruct>: Given the context 'The predicted amino-acid sequence of this enzyme, termed XCE, consists of 775 amino-acids with a single putative membrane-spanning region, an N-terminal cytoplasmic domain of 59 residues, and a large luminal domain that contains a characteristic zinc-binding motif.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [xce]
<Options>: A: xcenp-e (xenopus laevis) (centromere protein e s homeolog (xenopus laevis)) (aka centromere protein e s homeolog)
B: xce (mus musculus) (x chromosome inactivation center (mus musculus)) (aka x chromosome inactivation center)
C: xct (homo sapiens) (aka solute carrier family 7 member 11)
D: xcca (xenopus laevis) (trna nucleotidyl transferase, cca-adding, 1 s homeolog (xenopus laevis)) (aka trna nucleotidyl transferase, cca-adding, 1 s homeolog)
E: x chromosome controlling element (homo sapiens) (aka x chromosome controlling element)
F: None of the above. | [F] |
<Instruct>: Given the context 'XCE mRNA was found to be predominantly expressed in the central nervous system, sympathetic ganglia and in uterine subepithelial cells.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [xce]
<Options>: A: xcenp-e (xenopus laevis) (centromere protein e s homeolog (xenopus laevis)) (aka centromere protein e s homeolog)
B: xcca (xenopus laevis) (trna nucleotidyl transferase, cca-adding, 1 s homeolog (xenopus laevis)) (aka trna nucleotidyl transferase, cca-adding, 1 s homeolog)
C: xcel (xenopus tropicalis) (aka carboxyl ester lipase, gene 2)
D: xct (homo sapiens) (aka solute carrier family 7 member 11)
E: xcxcra (xenopus laevis) (aka c-x-c chemokine receptor type a)
F: None of the above. | [F] |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.