instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'Using fluorescent in situ hybridization, we localized hBNPI to the long arm of chromosome 19 (19q13) in close proximity to the late-onset familial Alzheimer's disease locus.', select the correct biomedical concept corresponding to 'hbnpi'. Answer using one of the provided options. | <Options>: A: npipb1p (homo sapiens) (aka nuclear pore complex interacting protein family member b1, pseudogene)
B: hbi (homo sapiens) (aka fkbp prolyl isomerase 4)
C: pni (homo sapiens) (aka serpin family e member 2)
D: bnpi (homo sapiens) (aka solute carrier family 17 member 7)
E: nprbi (homo sapiens) (aka natriuretic peptide receptor 2)
F: None of the above. | D |
<Instruct>: Given the context 'In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase.
Rab8 is a small GTP-binding protein that plays a role in vesicular transport from the trans-Golgi network to the basolateral plasma membrane in polarized epithelial cells (MDCK), and to the dendritic surface in hippocampal neurons.', select the correct biomedical concept corresponding to 'rab8'. Answer using one of the provided options. | <Options>: A: rab8b, member ras oncogene family (homo sapiens) (aka rab8b, member ras oncogene family)
B: rab28, member ras oncogene family (homo sapiens) (aka rab28, member ras oncogene family)
C: rab8 (drosophila melanogaster) (aka rab8)
D: rab8a, member ras oncogene family l homeolog (xenopus laevis) (aka rab8a, member ras oncogene family l homeolog)
E: rab8a (homo sapiens) (aka rab8a, member ras oncogene family)
F: None of the above. | E |
<Instruct>: Given the context 'In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase.
Rab8 is a small GTP-binding protein that plays a role in vesicular transport from the trans-Golgi network to the basolateral plasma membrane in polarized epithelial cells (MDCK), and to the dendritic surface in hippocampal neurons.', select the correct biomedical concept corresponding to 'rab8'. Answer using one of the provided options. | <Options>: A: rab8 (drosophila melanogaster) (aka rab8)
B: rab8 (homo sapiens) (aka rab8a, member ras oncogene family)
C: rab8b, member ras oncogene family (homo sapiens) (aka rab8b, member ras oncogene family)
D: rab28, member ras oncogene family (homo sapiens) (aka rab28, member ras oncogene family)
E: rab8a, member ras oncogene family l homeolog (xenopus laevis) (aka rab8a, member ras oncogene family l homeolog)
F: None of the above. | B |
<Instruct>: Given the context 'As is the case for most other rab proteins, the precise molecular interactions by which rab8 carries out its function remain to be elucidated.', select the correct biomedical concept corresponding to 'rab8'. Answer using one of the provided options. | <Options>: A: rab8 (drosophila melanogaster) (aka rab8)
B: rab8a, member ras oncogene family (mus musculus) (aka rab8a, member ras oncogene family)
C: rab8a, member ras oncogene family (homo sapiens) (aka rab8a, member ras oncogene family)
D: rabin8 (homo sapiens) (aka rab3a interacting protein)
E: rab28, member ras oncogene family (homo sapiens) (aka rab28, member ras oncogene family)
F: None of the above. | C |
<Instruct>: Given the context 'Here we report the identification and the complete cDNA-derived amino acid sequence of a murine rab8-interacting protein (rab8ip) that specifically interacts with rab8 in a GTP-dependent manner.', select the correct biomedical concept corresponding to 'rab8-interacting protein'. Answer using one of the provided options. | <Options>: A: rab8a (homo sapiens) (aka rab8a, member ras oncogene family)
B: rab5ip (homo sapiens) (aka sad1 and unc84 domain containing 2)
C: rab8ip (mus musculus) (aka mitogen-activated protein kinase kinase kinase kinase 2)
D: rab3a interacting protein (xenopus tropicalis) (aka rab3a interacting protein)
E: rab3ip (homo sapiens) (aka rab3a interacting protein)
F: None of the above. | C |
<Instruct>: Given the context 'Here we report the identification and the complete cDNA-derived amino acid sequence of a murine rab8-interacting protein (rab8ip) that specifically interacts with rab8 in a GTP-dependent manner.', select the correct biomedical concept corresponding to 'rab8ip'. Answer using one of the provided options. | <Options>: A: rab8ipl1 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 3)
B: rab8ip (mus musculus) (aka mitogen-activated protein kinase kinase kinase kinase 2)
C: rab3ip (homo sapiens) (aka rab3a interacting protein)
D: rab6ip1 (homo sapiens) (aka denn domain containing 5a)
E: mcm8ip (homo sapiens) (aka homologous recombination factor with ob-fold)
F: None of the above. | B |
<Instruct>: Given the context 'Here we report the identification and the complete cDNA-derived amino acid sequence of a murine rab8-interacting protein (rab8ip) that specifically interacts with rab8 in a GTP-dependent manner.', select the correct biomedical concept corresponding to 'rab8'. Answer using one of the provided options. | <Options>: A: rab8a, member ras oncogene family l homeolog (xenopus laevis) (aka rab8a, member ras oncogene family l homeolog)
B: rab8 (drosophila melanogaster) (aka rab8)
C: rabin8 (homo sapiens) (aka rab3a interacting protein)
D: rab28, member ras oncogene family (homo sapiens) (aka rab28, member ras oncogene family)
E: rab8a, member ras oncogene family (homo sapiens) (aka rab8a, member ras oncogene family)
F: None of the above. | E |
<Instruct>: Given the context 'Rab8ip displays 93% identity with the GC kinase, a serine/threonine protein kinase recently identified in human lymphoid tissue that is activated in the stress response.', select the correct biomedical concept corresponding to 'rab8ip'. Answer using one of the provided options. | <Options>: A: prkm8ip (homo sapiens) (aka mitogen-activated protein kinase 8 interacting protein 1)
B: rab5ip (homo sapiens) (aka sad1 and unc84 domain containing 2)
C: rab8ip (mus musculus) (aka mitogen-activated protein kinase kinase kinase kinase 2)
D: mcm8ip (homo sapiens) (aka homologous recombination factor with ob-fold)
E: rab8ipl1 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 3)
F: None of the above. | C |
<Instruct>: Given the context 'Rab8ip displays 93% identity with the GC kinase, a serine/threonine protein kinase recently identified in human lymphoid tissue that is activated in the stress response.', select the correct biomedical concept corresponding to 'gc kinase'. Answer using one of the provided options. | <Options>: A: gck (xenopus tropicalis) (aka glucokinase (hexokinase 4))
B: gck (homo sapiens) (mitogen-activated protein kinase kinase kinase kinase 2 (homo sapiens)) (aka mitogen-activated protein kinase kinase kinase kinase 2)
C: gck (homo sapiens) (glucokinase (homo sapiens)) (aka glucokinase)
D: gck (xenopus laevis) (aka glucokinase (hexokinase 4) l homeolog)
E: gck-1 (caenorhabditis elegans) (aka germinal center kinase 1;non-specific serine/threonine protein kinase)
F: None of the above. | B |
<Instruct>: Given the context 'Rab8ip displays 93% identity with the GC kinase, a serine/threonine protein kinase recently identified in human lymphoid tissue that is activated in the stress response.', select the correct biomedical concept corresponding to 'gc kinase'. Answer using one of the provided options. | <Options>: A: gck (xenopus tropicalis) (aka glucokinase (hexokinase 4))
B: gnk (homo sapiens) (aka n-acetylglucosamine kinase)
C: eif-2-alpha kinase gcn2 (glycine max) (aka eif-2-alpha kinase gcn2)
D: gck (homo sapiens) (glucokinase (homo sapiens)) (aka glucokinase)
E: serine/threonine-protein kinase gcn2 (saccharomyces cerevisiae s288c) (aka serine/threonine-protein kinase gcn2)
F: None of the above. | F |
<Instruct>: Given the context 'Like the GC kinase, rab8ip has protein kinase activity manifested by autophosphorylation and phosphorylation of the classical serine/threonine protein kinase substrates, myelin basic protein and casein.', select the correct biomedical concept corresponding to 'gc kinase'. Answer using one of the provided options. | <Options>: A: gnk (homo sapiens) (aka n-acetylglucosamine kinase)
B: gck (homo sapiens) (mitogen-activated protein kinase kinase kinase kinase 2 (homo sapiens)) (aka mitogen-activated protein kinase kinase kinase kinase 2)
C: gck (xenopus laevis) (aka glucokinase (hexokinase 4) l homeolog)
D: gck-1 (caenorhabditis elegans) (aka germinal center kinase 1;non-specific serine/threonine protein kinase)
E: gck (homo sapiens) (glucokinase (homo sapiens)) (aka glucokinase)
F: None of the above. | B |
<Instruct>: Given the context 'Like the GC kinase, rab8ip has protein kinase activity manifested by autophosphorylation and phosphorylation of the classical serine/threonine protein kinase substrates, myelin basic protein and casein.', select the correct biomedical concept corresponding to 'rab8ip'. Answer using one of the provided options. | <Options>: A: rab8ip (mus musculus) (aka mitogen-activated protein kinase kinase kinase kinase 2)
B: rab5ip (homo sapiens) (aka sad1 and unc84 domain containing 2)
C: prkm8ip (homo sapiens) (aka mitogen-activated protein kinase 8 interacting protein 1)
D: rab8ip (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 2)
E: rab6ip1 (homo sapiens) (aka denn domain containing 5a)
F: None of the above. | A |
<Instruct>: Given the context 'Like the GC kinase, rab8ip has protein kinase activity manifested by autophosphorylation and phosphorylation of the classical serine/threonine protein kinase substrates, myelin basic protein and casein.', select the correct biomedical concept corresponding to 'myelin basic protein'. Answer using one of the provided options. | <Options>: A: myelin basic protein (bos taurus) (aka myelin basic protein)
B: myelin basic protein (homo sapiens) (aka myelin basic protein)
C: myelin basic protein (rattus norvegicus) (aka myelin basic protein)
D: myelin-associated oligodendrocytic basic protein (mus musculus) (aka myelin-associated oligodendrocytic basic protein)
E: myelin basic protein (xenopus tropicalis) (aka myelin basic protein)
F: None of the above. | B |
<Instruct>: Given the context 'When coexpressed in transfected 293T cells, rab8 and the rab8ip/GC kinase formed a complex that could be recovered by immunoprecipitation with antibodies to rab8.', select the correct biomedical concept corresponding to 'rab8'. Answer using one of the provided options. | <Options>: A: rab8 (drosophila melanogaster) (aka rab8)
B: rabin8 (homo sapiens) (aka rab3a interacting protein)
C: rab8b, member ras oncogene family (homo sapiens) (aka rab8b, member ras oncogene family)
D: rab28, member ras oncogene family (homo sapiens) (aka rab28, member ras oncogene family)
E: rab8a, member ras oncogene family (homo sapiens) (aka rab8a, member ras oncogene family)
F: None of the above. | E |
<Instruct>: Given the context 'When coexpressed in transfected 293T cells, rab8 and the rab8ip/GC kinase formed a complex that could be recovered by immunoprecipitation with antibodies to rab8.', select the correct biomedical concept corresponding to 'rab8ip'. Answer using one of the provided options. | <Options>: A: rab8ip (mus musculus) (aka mitogen-activated protein kinase kinase kinase kinase 2)
B: mcm8ip (homo sapiens) (aka homologous recombination factor with ob-fold)
C: prkm8ip (homo sapiens) (aka mitogen-activated protein kinase 8 interacting protein 1)
D: rab6ip1 (homo sapiens) (aka denn domain containing 5a)
E: rab5ip (homo sapiens) (aka sad1 and unc84 domain containing 2)
F: None of the above. | A |
<Instruct>: Given the context 'When coexpressed in transfected 293T cells, rab8 and the rab8ip/GC kinase formed a complex that could be recovered by immunoprecipitation with antibodies to rab8.', select the correct biomedical concept corresponding to 'gc kinase'. Answer using one of the provided options. | <Options>: A: serine/threonine-protein kinase gcn2 (saccharomyces cerevisiae s288c) (aka serine/threonine-protein kinase gcn2)
B: gck-2 (caenorhabditis elegans) (aka mitogen-activated protein kinase kinase kinase kinase)
C: gck (xenopus laevis) (aka glucokinase (hexokinase 4) l homeolog)
D: eif-2-alpha kinase gcn2 (glycine max) (aka eif-2-alpha kinase gcn2)
E: gck (homo sapiens) (mitogen-activated protein kinase kinase kinase kinase 2 (homo sapiens)) (aka mitogen-activated protein kinase kinase kinase kinase 2)
F: None of the above. | E |
<Instruct>: Given the context 'When coexpressed in transfected 293T cells, rab8 and the rab8ip/GC kinase formed a complex that could be recovered by immunoprecipitation with antibodies to rab8.', select the correct biomedical concept corresponding to 'rab8'. Answer using one of the provided options. | <Options>: A: rab8b, member ras oncogene family (homo sapiens) (aka rab8b, member ras oncogene family)
B: rab8 (drosophila melanogaster) (aka rab8)
C: rab8a, member ras oncogene family (homo sapiens) (aka rab8a, member ras oncogene family)
D: rab8a, member ras oncogene family (mus musculus) (aka rab8a, member ras oncogene family)
E: rabin8 (homo sapiens) (aka rab3a interacting protein)
F: None of the above. | C |
<Instruct>: Given the context 'Cell fractionation and immunofluorescence analyses indicate that in MDCK cells endogenous rab8ip is present both in the cytosol and as a peripheral membrane protein concentrated in the Golgi region and basolateral plasma membrane domains, sites where rab8 itself is also located.', select the correct biomedical concept corresponding to 'rab8ip'. Answer using one of the provided options. | <Options>: A: prkm8ip (homo sapiens) (aka mitogen-activated protein kinase 8 interacting protein 1)
B: rab8ip (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 2)
C: rab8ip (mus musculus) (aka mitogen-activated protein kinase kinase kinase kinase 2)
D: rab3a interacting protein (homo sapiens) (aka rab3a interacting protein)
E: rab5ip (homo sapiens) (aka sad1 and unc84 domain containing 2)
F: None of the above. | C |
<Instruct>: Given the context 'Cell fractionation and immunofluorescence analyses indicate that in MDCK cells endogenous rab8ip is present both in the cytosol and as a peripheral membrane protein concentrated in the Golgi region and basolateral plasma membrane domains, sites where rab8 itself is also located.', select the correct biomedical concept corresponding to 'rab8'. Answer using one of the provided options. | <Options>: A: rab8 (drosophila melanogaster) (aka rab8)
B: rab28, member ras oncogene family (homo sapiens) (aka rab28, member ras oncogene family)
C: rab8a, member ras oncogene family (mus musculus) (aka rab8a, member ras oncogene family)
D: rabin8 (homo sapiens) (aka rab3a interacting protein)
E: rab8 (homo sapiens) (aka rab8a, member ras oncogene family)
F: None of the above. | E |
<Instruct>: Given the context 'In light of recent evidence that rab proteins may act by promoting the stabilization of SNARE complexes, the specific GTP-dependent association of rab8 with the rab8ip/GC kinase raises the possibility that rab-regulated protein phosphorylation is important for vesicle targeting or fusion.', select the correct biomedical concept corresponding to 'rab8'. Answer using one of the provided options. | <Options>: A: rab8a, member ras oncogene family l homeolog (xenopus laevis) (aka rab8a, member ras oncogene family l homeolog)
B: rab8b, member ras oncogene family (homo sapiens) (aka rab8b, member ras oncogene family)
C: mel (homo sapiens) (rab8a, member ras oncogene family (homo sapiens)) (aka rab8a, member ras oncogene family)
D: rab8a, member ras oncogene family (mus musculus) (aka rab8a, member ras oncogene family)
E: rab8 (drosophila melanogaster) (aka rab8)
F: None of the above. | C |
<Instruct>: Given the context 'In light of recent evidence that rab proteins may act by promoting the stabilization of SNARE complexes, the specific GTP-dependent association of rab8 with the rab8ip/GC kinase raises the possibility that rab-regulated protein phosphorylation is important for vesicle targeting or fusion.', select the correct biomedical concept corresponding to 'rab8'. Answer using one of the provided options. | <Options>: A: rab8 (drosophila melanogaster) (aka rab8)
B: rab8a, member ras oncogene family l homeolog (xenopus laevis) (aka rab8a, member ras oncogene family l homeolog)
C: rab8a, member ras oncogene family (mus musculus) (aka rab8a, member ras oncogene family)
D: rab8b, member ras oncogene family (homo sapiens) (aka rab8b, member ras oncogene family)
E: rabin8 (homo sapiens) (aka rab3a interacting protein)
F: None of the above. | F |
<Instruct>: Given the context 'In light of recent evidence that rab proteins may act by promoting the stabilization of SNARE complexes, the specific GTP-dependent association of rab8 with the rab8ip/GC kinase raises the possibility that rab-regulated protein phosphorylation is important for vesicle targeting or fusion.', select the correct biomedical concept corresponding to 'rab8ip'. Answer using one of the provided options. | <Options>: A: rab5ip (homo sapiens) (aka sad1 and unc84 domain containing 2)
B: rab6ip1 (homo sapiens) (aka denn domain containing 5a)
C: rab8ip (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 2)
D: rab8ip (mus musculus) (aka mitogen-activated protein kinase kinase kinase kinase 2)
E: rabin8 (homo sapiens) (aka rab3a interacting protein)
F: None of the above. | D |
<Instruct>: Given the context 'In light of recent evidence that rab proteins may act by promoting the stabilization of SNARE complexes, the specific GTP-dependent association of rab8 with the rab8ip/GC kinase raises the possibility that rab-regulated protein phosphorylation is important for vesicle targeting or fusion.', select the correct biomedical concept corresponding to 'gc kinase'. Answer using one of the provided options. | <Options>: A: gck-1 (caenorhabditis elegans) (aka germinal center kinase 1;non-specific serine/threonine protein kinase)
B: serine/threonine-protein kinase gcn2 (saccharomyces cerevisiae s288c) (aka serine/threonine-protein kinase gcn2)
C: gck (homo sapiens) (glucokinase (homo sapiens)) (aka glucokinase)
D: gck (homo sapiens) (mitogen-activated protein kinase kinase kinase kinase 2 (homo sapiens)) (aka mitogen-activated protein kinase kinase kinase kinase 2)
E: gck (xenopus tropicalis) (aka glucokinase (hexokinase 4))
F: None of the above. | D |
<Instruct>: Given the context 'Moreover, the rab8ip/GC kinase may serve to modulate secretion in response to stress stimuli.', select the correct biomedical concept corresponding to 'rab8ip'. Answer using one of the provided options. | <Options>: A: mcm8ip (homo sapiens) (aka homologous recombination factor with ob-fold)
B: rab3ip (homo sapiens) (aka rab3a interacting protein)
C: rab6ip1 (homo sapiens) (aka denn domain containing 5a)
D: rab5ip (homo sapiens) (aka sad1 and unc84 domain containing 2)
E: rab8ip (mus musculus) (aka mitogen-activated protein kinase kinase kinase kinase 2)
F: None of the above. | E |
<Instruct>: Given the context 'Moreover, the rab8ip/GC kinase may serve to modulate secretion in response to stress stimuli.', select the correct biomedical concept corresponding to 'gc kinase'. Answer using one of the provided options. | <Options>: A: gck-a (xenopus laevis) (aka glucokinase (hexokinase 4) l homeolog)
B: gck (homo sapiens) (mitogen-activated protein kinase kinase kinase kinase 2 (homo sapiens)) (aka mitogen-activated protein kinase kinase kinase kinase 2)
C: gck (homo sapiens) (glucokinase (homo sapiens)) (aka glucokinase)
D: serine/threonine-protein kinase gcn2 (saccharomyces cerevisiae s288c) (aka serine/threonine-protein kinase gcn2)
E: gnk (homo sapiens) (aka n-acetylglucosamine kinase)
F: None of the above. | B |
<Instruct>: Given the context 'The contribution of the two transporter isoforms to monoamine storage in human neuroendocrine tissues was examined with isoform-specific polyclonal antibodies against hVMAT1 and hVMAT2.', select the correct biomedical concept corresponding to 'hvmat1'. Answer using one of the provided options. | <Options>: A: n6amt1 (homo sapiens) (aka hemk methyltransferase 2, etf1 glutamine and histone h4 lysine)
B: vmat1 (homo sapiens) (aka solute carrier family 18 member a1)
C: solute carrier family 18 (vesicular monoamine), member 1 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 1)
D: hvt1 (arabidopsis thaliana) (aka helicase in vascular tissue and tapetum)
E: amino acid transporter avt1j-like (glycine max) (aka amino acid transporter avt1j-like)
F: None of the above. | B |
<Instruct>: Given the context 'The contribution of the two transporter isoforms to monoamine storage in human neuroendocrine tissues was examined with isoform-specific polyclonal antibodies against hVMAT1 and hVMAT2.', select the correct biomedical concept corresponding to 'hvmat2'. Answer using one of the provided options. | <Options>: A: n6amt2 (homo sapiens) (aka eef1a lysine methyltransferase 1)
B: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 (mus musculus) (aka solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2)
C: solute carrier family 9, subfamily b (nha2, cation proton antiporter 2), member 2 (mus musculus) (aka solute carrier family 9, subfamily b (nha2, cation proton antiporter 2), member 2)
D: vat2 (homo sapiens) (aka solute carrier family 18 member a2)
E: avt2 (homo sapiens) (aka solute carrier family 38 member 11)
F: None of the above. | D |
<Instruct>: Given the context 'Central, peripheral, and enteric neurons express only VMAT2.', select the correct biomedical concept corresponding to 'vmat2'. Answer using one of the provided options. | <Options>: A: eaat2 (homo sapiens) (aka solute carrier family 1 member 2)
B: vmat2 (homo sapiens) (aka solute carrier family 18 member a2)
C: slc6a2 (homo sapiens) (aka solute carrier family 6 member 2)
D: vglut2 (homo sapiens) (aka solute carrier family 17 member 6)
E: vmat1 (homo sapiens) (aka solute carrier family 18 member a1)
F: None of the above. | B |
<Instruct>: Given the context 'VMAT1 is expressed exclusively in neuroendocrine, including chromaffin and enterochromaffin, cells.', select the correct biomedical concept corresponding to 'vmat1'. Answer using one of the provided options. | <Options>: A: vmat1 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 1)
B: vmat2 (homo sapiens) (aka solute carrier family 18 member a2)
C: vmat-1 (rattus norvegicus) (aka solute carrier family 18 member a1)
D: slc18a1 (homo sapiens) (aka solute carrier family 18 member a1)
E: viaat (homo sapiens) (aka solute carrier family 32 member 1)
F: None of the above. | D |
<Instruct>: Given the context 'VMAT1 and VMAT2 are coexpressed in all chromaffin cells of the adrenal medulla.', select the correct biomedical concept corresponding to 'vmat1'. Answer using one of the provided options. | <Options>: A: slc18a1 (homo sapiens) (aka solute carrier family 18 member a1)
B: viaat (homo sapiens) (aka solute carrier family 32 member 1)
C: vesicle amine transport 1 (homo sapiens) (aka vesicle amine transport 1)
D: vmat2 (homo sapiens) (aka solute carrier family 18 member a2)
E: vat1 (mus musculus) (solute carrier family 18 (vesicular monoamine), member 1 (mus musculus)) (aka solute carrier family 18 (vesicular monoamine), member 1)
F: None of the above. | A |
<Instruct>: Given the context 'VMAT1 and VMAT2 are coexpressed in all chromaffin cells of the adrenal medulla.', select the correct biomedical concept corresponding to 'vmat2'. Answer using one of the provided options. | <Options>: A: solute carrier family 18 (vesicular monoamine), member 2 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 2)
B: eaat2 (homo sapiens) (aka solute carrier family 1 member 2)
C: vmat2 (homo sapiens) (aka solute carrier family 18 member a2)
D: vmat1 (homo sapiens) (aka solute carrier family 18 member a1)
E: vmat2 (rattus norvegicus) (aka solute carrier family 18 member a2)
F: None of the above. | C |
<Instruct>: Given the context 'VMAT1 and VMAT2 are coexpressed in all chromaffin cells of the adrenal medulla.', select the correct biomedical concept corresponding to 'vmat2'. Answer using one of the provided options. | <Options>: A: vmat2 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 2)
B: eaat2 (homo sapiens) (aka solute carrier family 1 member 2)
C: vmat1 (homo sapiens) (aka solute carrier family 18 member a1)
D: slc6a2 (homo sapiens) (aka solute carrier family 6 member 2)
E: vglut2 (homo sapiens) (aka solute carrier family 17 member 6)
F: None of the above. | F |
<Instruct>: Given the context 'VMAT2 alone is expressed in histamine-storing enterochromaffin-like cells of the oxyntic mucosa of the stomach.', select the correct biomedical concept corresponding to 'vmat2'. Answer using one of the provided options. | <Options>: A: eaat2 (homo sapiens) (aka solute carrier family 1 member 2)
B: vmat1 (homo sapiens) (aka solute carrier family 18 member a1)
C: vglut2 (homo sapiens) (aka solute carrier family 17 member 6)
D: vat2 (homo sapiens) (aka solute carrier family 18 member a2)
E: vmat2 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 2)
F: None of the above. | D |
<Instruct>: Given the context 'Catecholamines exhibit a 3-fold higher affinity, and histamine exhibits a 30-fold higher affinity, for VMAT2.', select the correct biomedical concept corresponding to 'vmat2'. Answer using one of the provided options. | <Options>: A: vat2 (homo sapiens) (aka solute carrier family 18 member a2)
B: vmat2 (rattus norvegicus) (aka solute carrier family 18 member a2)
C: vmat1 (homo sapiens) (aka solute carrier family 18 member a1)
D: eaat2 (homo sapiens) (aka solute carrier family 1 member 2)
E: slc6a2 (homo sapiens) (aka solute carrier family 6 member 2)
F: None of the above. | A |
<Instruct>: Given the context 'Reserpine and ketanserin are slightly more potent inhibitors of VMAT2-mediated transport than of VMAT1-mediated transport, whereas tetrabenazine binds to and inhibits only VMAT2.', select the correct biomedical concept corresponding to 'vmat2'. Answer using one of the provided options. | <Options>: A: solute carrier family 18 (vesicular monoamine), member 2 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 2)
B: vglut2 (homo sapiens) (aka solute carrier family 17 member 6)
C: vmat2 (homo sapiens) (aka solute carrier family 18 member a2)
D: slc6a2 (homo sapiens) (aka solute carrier family 6 member 2)
E: eaat2 (homo sapiens) (aka solute carrier family 1 member 2)
F: None of the above. | C |
<Instruct>: Given the context 'Reserpine and ketanserin are slightly more potent inhibitors of VMAT2-mediated transport than of VMAT1-mediated transport, whereas tetrabenazine binds to and inhibits only VMAT2.', select the correct biomedical concept corresponding to 'vmat1'. Answer using one of the provided options. | <Options>: A: viaat (homo sapiens) (aka solute carrier family 32 member 1)
B: vmat-1 (rattus norvegicus) (aka solute carrier family 18 member a1)
C: vmat2 (homo sapiens) (aka solute carrier family 18 member a2)
D: vat1 (mus musculus) (solute carrier family 18 (vesicular monoamine), member 1 (mus musculus)) (aka solute carrier family 18 (vesicular monoamine), member 1)
E: vat1 (homo sapiens) (solute carrier family 18 member a1 (homo sapiens)) (aka solute carrier family 18 member a1)
F: None of the above. | E |
<Instruct>: Given the context 'Reserpine and ketanserin are slightly more potent inhibitors of VMAT2-mediated transport than of VMAT1-mediated transport, whereas tetrabenazine binds to and inhibits only VMAT2.', select the correct biomedical concept corresponding to 'vmat2'. Answer using one of the provided options. | <Options>: A: slc6a2 (homo sapiens) (aka solute carrier family 6 member 2)
B: vat2 (homo sapiens) (aka solute carrier family 18 member a2)
C: vmat-2 (rattus norvegicus) (aka solute carrier family 18 member a2)
D: solute carrier family 18 (vesicular monoamine), member 2 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 2)
E: vmat1 (homo sapiens) (aka solute carrier family 18 member a1)
F: None of the above. | B |
<Instruct>: Given the context 'N-methyl-4-phenylpyridinium, phenylethylamine, amphetamine, and methylenedioxymethamphetamine are all more potent inhibitors of VMAT2 than of VMAT1, whereas fenfluramine is a more potent inhibitor of VMAT1-mediated monamine transport than of VMAT2-mediated monoamine transport.', select the correct biomedical concept corresponding to 'vmat2'. Answer using one of the provided options. | <Options>: A: vglut2 (homo sapiens) (aka solute carrier family 17 member 6)
B: vmat-2 (rattus norvegicus) (aka solute carrier family 18 member a2)
C: eaat2 (homo sapiens) (aka solute carrier family 1 member 2)
D: solute carrier family 18 (vesicular monoamine), member 2 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 2)
E: vat2 (homo sapiens) (aka solute carrier family 18 member a2)
F: None of the above. | E |
<Instruct>: Given the context 'N-methyl-4-phenylpyridinium, phenylethylamine, amphetamine, and methylenedioxymethamphetamine are all more potent inhibitors of VMAT2 than of VMAT1, whereas fenfluramine is a more potent inhibitor of VMAT1-mediated monamine transport than of VMAT2-mediated monoamine transport.', select the correct biomedical concept corresponding to 'vmat1'. Answer using one of the provided options. | <Options>: A: vmat-1 (rattus norvegicus) (aka solute carrier family 18 member a1)
B: viaat (homo sapiens) (aka solute carrier family 32 member 1)
C: vmat1 (homo sapiens) (aka solute carrier family 18 member a1)
D: vat1 (mus musculus) (solute carrier family 18 (vesicular monoamine), member 1 (mus musculus)) (aka solute carrier family 18 (vesicular monoamine), member 1)
E: vesicle amine transport 1 (homo sapiens) (aka vesicle amine transport 1)
F: None of the above. | C |
<Instruct>: Given the context 'N-methyl-4-phenylpyridinium, phenylethylamine, amphetamine, and methylenedioxymethamphetamine are all more potent inhibitors of VMAT2 than of VMAT1, whereas fenfluramine is a more potent inhibitor of VMAT1-mediated monamine transport than of VMAT2-mediated monoamine transport.', select the correct biomedical concept corresponding to 'vmat1'. Answer using one of the provided options. | <Options>: A: vmat2 (homo sapiens) (aka solute carrier family 18 member a2)
B: solute carrier family 18 (vesicular monoamine), member 1 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 1)
C: viaat (homo sapiens) (aka solute carrier family 32 member 1)
D: vmat-1 (rattus norvegicus) (aka solute carrier family 18 member a1)
E: vat1 (homo sapiens) (solute carrier family 18 member a1 (homo sapiens)) (aka solute carrier family 18 member a1)
F: None of the above. | E |
<Instruct>: Given the context 'N-methyl-4-phenylpyridinium, phenylethylamine, amphetamine, and methylenedioxymethamphetamine are all more potent inhibitors of VMAT2 than of VMAT1, whereas fenfluramine is a more potent inhibitor of VMAT1-mediated monamine transport than of VMAT2-mediated monoamine transport.', select the correct biomedical concept corresponding to 'vmat2'. Answer using one of the provided options. | <Options>: A: eaat2 (homo sapiens) (aka solute carrier family 1 member 2)
B: vmat2 (homo sapiens) (aka solute carrier family 18 member a2)
C: vglut2 (homo sapiens) (aka solute carrier family 17 member 6)
D: vmat-2 (rattus norvegicus) (aka solute carrier family 18 member a2)
E: slc6a2 (homo sapiens) (aka solute carrier family 6 member 2)
F: None of the above. | B |
<Instruct>: Given the context 'The unique distributions of hVMAT1 and hVMAT2 provide new markers for multiple neuroendocrine lineages, and examination of their transport properties provides mechanistic insights into the pharmacology and physiology of amine storage in cardiovascular, endocrine, and central nervous system function.', select the correct biomedical concept corresponding to 'hvmat1'. Answer using one of the provided options. | <Options>: A: solute carrier family 18 (vesicular monoamine), member 1 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 1)
B: vmat1 (homo sapiens) (aka solute carrier family 18 member a1)
C: maat1 (homo sapiens) (aka mitochondrial ribosomal protein l28)
D: amino acid transporter avt1j (glycine max) (aka amino acid transporter avt1j)
E: hvmt1 (mus musculus) (aka heavy metal tolerance protein 1)
F: None of the above. | B |
<Instruct>: Given the context 'The unique distributions of hVMAT1 and hVMAT2 provide new markers for multiple neuroendocrine lineages, and examination of their transport properties provides mechanistic insights into the pharmacology and physiology of amine storage in cardiovascular, endocrine, and central nervous system function.', select the correct biomedical concept corresponding to 'hvmat1'. Answer using one of the provided options. | <Options>: A: amino acid transporter avt1j (glycine max) (aka amino acid transporter avt1j)
B: n6amt1 (homo sapiens) (aka hemk methyltransferase 2, etf1 glutamine and histone h4 lysine)
C: hvmt1 (mus musculus) (aka heavy metal tolerance protein 1)
D: vmat1 (mus musculus) (aka solute carrier family 18 (vesicular monoamine), member 1)
E: maat1 (homo sapiens) (aka mitochondrial ribosomal protein l28)
F: None of the above. | F |
<Instruct>: Given the context 'The unique distributions of hVMAT1 and hVMAT2 provide new markers for multiple neuroendocrine lineages, and examination of their transport properties provides mechanistic insights into the pharmacology and physiology of amine storage in cardiovascular, endocrine, and central nervous system function.', select the correct biomedical concept corresponding to 'hvmat2'. Answer using one of the provided options. | <Options>: A: solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 (mus musculus) (aka solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2)
B: vstm2 (homo sapiens) (aka v-set and transmembrane domain containing 2a)
C: vat2 (homo sapiens) (aka solute carrier family 18 member a2)
D: avt2 (homo sapiens) (aka solute carrier family 38 member 11)
E: n6amt2 (homo sapiens) (aka eef1a lysine methyltransferase 1)
F: None of the above. | C |
<Instruct>: Given the context 'The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.
', select the correct biomedical concept corresponding to 'c/ebpalpha'. Answer using one of the provided options. | <Options>: A: c/ebp-beta (homo sapiens) (aka ccaat enhancer binding protein beta)
B: ccaat enhancer binding protein alpha (homo sapiens) (aka ccaat enhancer binding protein alpha)
C: c/ebpalpha (xenopus tropicalis) (aka ccaat enhancer binding protein alpha)
D: c/ebpbeta (xenopus tropicalis) (aka ccaat enhancer binding protein beta)
E: None of the above. | B |
<Instruct>: Given the context 'The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.
', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: ob (homo sapiens) (leptin (homo sapiens)) (aka leptin)
B: ob1 (gallus gallus) (aka hop homeobox)
C: obp-1 (homo sapiens) (aka kinesin family member 22)
D: obv (drosophila melanogaster) (aka centrosomin)
E: ob (oryctolagus cuniculus) (aka leptin)
F: None of the above. | A |
<Instruct>: Given the context 'The ob gene product, leptin, apparently exclusively expressed in adipose tissue, is a signaling factor regulating body weight homeostasis and energy balance.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: obp (drosophila melanogaster) (aka optix-binding protein)
B: obf (homo sapiens) (aka izumo sperm-oocyte fusion 1)
C: obr (homo sapiens) (aka leptin receptor)
D: ob (homo sapiens) (leptin (homo sapiens)) (aka leptin)
E: ob (oryctolagus cuniculus) (aka leptin)
F: None of the above. | D |
<Instruct>: Given the context 'The ob gene product, leptin, apparently exclusively expressed in adipose tissue, is a signaling factor regulating body weight homeostasis and energy balance.', select the correct biomedical concept corresponding to 'leptin'. Answer using one of the provided options. | <Options>: A: leptin (gallus gallus) (aka leptin)
B: leptin (oryctolagus cuniculus) (aka leptin)
C: leptin, serum levels of (homo sapiens) (aka leptin, serum levels of)
D: leptin (rattus norvegicus) (aka leptin)
E: ob (homo sapiens) (leptin (homo sapiens)) (aka leptin)
F: None of the above. | E |
<Instruct>: Given the context 'ob gene expression is increased in obese rodents and regulated by feeding, insulin, and glucocorticoids, which supports the concept that ob gene expression is under hormonal control, which is expected for a key factor controlling body weight homeostasis and energy balance.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: leptin (homo sapiens) (aka leptin)
B: obv (drosophila melanogaster) (aka centrosomin)
C: ob1 (gallus gallus) (aka hop homeobox)
D: obr (homo sapiens) (aka leptin receptor)
E: obp (drosophila melanogaster) (aka optix-binding protein)
F: None of the above. | A |
<Instruct>: Given the context 'ob gene expression is increased in obese rodents and regulated by feeding, insulin, and glucocorticoids, which supports the concept that ob gene expression is under hormonal control, which is expected for a key factor controlling body weight homeostasis and energy balance.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: obr (homo sapiens) (aka leptin receptor)
B: ob (oryctolagus cuniculus) (aka leptin)
C: ob (homo sapiens) (leptin (homo sapiens)) (aka leptin)
D: obf (homo sapiens) (aka izumo sperm-oocyte fusion 1)
E: obp-1 (homo sapiens) (aka kinesin family member 22)
F: None of the above. | C |
<Instruct>: Given the context 'In humans, ob mRNA expression is increased in gross obesity; however, the effects of the above factors on human ob expression are unknown.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: obp-1 (homo sapiens) (aka kinesin family member 22)
B: ob (homo sapiens) (leptin (homo sapiens)) (aka leptin)
C: ob (drosophila melanogaster) (aka oblique)
D: ob (oryctolagus cuniculus) (aka leptin)
E: obr (homo sapiens) (aka leptin receptor)
F: None of the above. | B |
<Instruct>: Given the context 'In humans, ob mRNA expression is increased in gross obesity; however, the effects of the above factors on human ob expression are unknown.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: obv (drosophila melanogaster) (aka centrosomin)
B: leptin (homo sapiens) (aka leptin)
C: obp-1 (homo sapiens) (aka kinesin family member 22)
D: ob (oryctolagus cuniculus) (aka leptin)
E: ob1 (gallus gallus) (aka hop homeobox)
F: None of the above. | B |
<Instruct>: Given the context 'We describe the structure of the human ob gene and initial functional analysis of its promoter.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: obv (drosophila melanogaster) (aka centrosomin)
B: obf (homo sapiens) (aka izumo sperm-oocyte fusion 1)
C: obp (drosophila melanogaster) (aka optix-binding protein)
D: obp-1 (homo sapiens) (aka kinesin family member 22)
E: leptin (homo sapiens) (aka leptin)
F: None of the above. | E |
<Instruct>: Given the context 'We describe the structure of the human ob gene and initial functional analysis of its promoter.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: obp (drosophila melanogaster) (aka optix-binding protein)
B: obv (drosophila melanogaster) (aka centrosomin)
C: ob (oryctolagus cuniculus) (aka leptin)
D: obr (homo sapiens) (aka leptin receptor)
E: ob (drosophila melanogaster) (aka oblique)
F: None of the above. | F |
<Instruct>: Given the context 'The human ob gene's three exons cover approximately 15 kb of genomic DNA.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: ob (drosophila melanogaster) (aka oblique)
B: obv (drosophila melanogaster) (aka centrosomin)
C: ob (homo sapiens) (leptin (homo sapiens)) (aka leptin)
D: obp (drosophila melanogaster) (aka optix-binding protein)
E: obp-1 (homo sapiens) (aka kinesin family member 22)
F: None of the above. | C |
<Instruct>: Given the context 'Only 217 bp of 5' sequence are required for basal adipose tissue-specific expression of the ob gene as well as enhanced expression by C/EBPalpha.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: ob (homo sapiens) (leptin (homo sapiens)) (aka leptin)
B: obv (drosophila melanogaster) (aka centrosomin)
C: ob (drosophila melanogaster) (aka oblique)
D: obr (homo sapiens) (aka leptin receptor)
E: obp (drosophila melanogaster) (aka optix-binding protein)
F: None of the above. | A |
<Instruct>: Given the context 'Only 217 bp of 5' sequence are required for basal adipose tissue-specific expression of the ob gene as well as enhanced expression by C/EBPalpha.', select the correct biomedical concept corresponding to 'c/ebpalpha'. Answer using one of the provided options. | <Options>: A: c/ebp (xenopus tropicalis) (aka ccaat enhancer binding protein alpha)
B: c/ebp-beta (homo sapiens) (aka ccaat enhancer binding protein beta)
C: c/ebpbeta (xenopus tropicalis) (aka ccaat enhancer binding protein beta)
D: cebpa (homo sapiens) (aka ccaat enhancer binding protein alpha)
E: None of the above. | D |
<Instruct>: Given the context 'Mutation of the single C/EBPalpha site in this region abolished inducibility of the promoter by C/EBPalpha in cotransfection assays.', select the correct biomedical concept corresponding to 'c/ebpalpha'. Answer using one of the provided options. | <Options>: A: c/ebpbeta (xenopus tropicalis) (aka ccaat enhancer binding protein beta)
B: c/ebp-alpha (homo sapiens) (aka ccaat enhancer binding protein alpha)
C: c/ebp (xenopus tropicalis) (aka ccaat enhancer binding protein alpha)
D: c/ebp-beta (homo sapiens) (aka ccaat enhancer binding protein beta)
E: None of the above. | B |
<Instruct>: Given the context 'Mutation of the single C/EBPalpha site in this region abolished inducibility of the promoter by C/EBPalpha in cotransfection assays.', select the correct biomedical concept corresponding to 'c/ebpalpha'. Answer using one of the provided options. | <Options>: A: cebpa (homo sapiens) (aka ccaat enhancer binding protein alpha)
B: c/ebp-beta (homo sapiens) (aka ccaat enhancer binding protein beta)
C: ccaat enhancer binding protein alpha (xenopus tropicalis) (aka ccaat enhancer binding protein alpha)
D: c/ebpbeta (xenopus tropicalis) (aka ccaat enhancer binding protein beta)
E: None of the above. | A |
<Instruct>: Given the context 'The gene structure will facilitate our analysis of ob mutations in human obesity, whereas knowledge of sequence elements and factors regulating ob gene expression should be of major importance in the prevention and treatment of obesity.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: obp (drosophila melanogaster) (aka optix-binding protein)
B: ob (homo sapiens) (leptin (homo sapiens)) (aka leptin)
C: ob (drosophila melanogaster) (aka oblique)
D: ob1 (gallus gallus) (aka hop homeobox)
E: obp-1 (homo sapiens) (aka kinesin family member 22)
F: None of the above. | B |
<Instruct>: Given the context 'The gene structure will facilitate our analysis of ob mutations in human obesity, whereas knowledge of sequence elements and factors regulating ob gene expression should be of major importance in the prevention and treatment of obesity.', select the correct biomedical concept corresponding to 'ob'. Answer using one of the provided options. | <Options>: A: obf (homo sapiens) (aka izumo sperm-oocyte fusion 1)
B: ob (drosophila melanogaster) (aka oblique)
C: ob (homo sapiens) (leptin (homo sapiens)) (aka leptin)
D: ob (oryctolagus cuniculus) (aka leptin)
E: obp-1 (homo sapiens) (aka kinesin family member 22)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.
', select the correct biomedical concept corresponding to 'ara70'. Answer using one of the provided options. | <Options>: A: rpa70 (xenopus laevis) (replication protein a1 s homeolog (xenopus laevis)) (aka replication protein a1 s homeolog)
B: ara70 (mus musculus) (aka nuclear receptor coactivator 4)
C: ara160 (homo sapiens) (aka tata element modulatory factor 1)
D: crsp70 (homo sapiens) (aka mediator complex subunit 26)
E: ara70 (homo sapiens) (aka nuclear receptor coactivator 4)
F: None of the above. | E |
<Instruct>: Given the context 'Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.
', select the correct biomedical concept corresponding to 'androgen receptor'. Answer using one of the provided options. | <Options>: A: thyroid hormone receptor alpha (homo sapiens) (aka thyroid hormone receptor alpha)
B: ar (homo sapiens) (androgen receptor (homo sapiens)) (aka androgen receptor)
C: retinoid x receptor alpha (homo sapiens) (aka retinoid x receptor alpha)
D: androgen receptor (rattus norvegicus) (aka androgen receptor)
E: thra1 (homo sapiens) (aka nuclear receptor subfamily 1 group d member 1)
F: None of the above. | B |
<Instruct>: Given the context 'The androgen receptor (AR) is a member of the steroid receptor superfamily that plays an important role in male sexual differentiation and prostate cell proliferation.', select the correct biomedical concept corresponding to 'androgen receptor'. Answer using one of the provided options. | <Options>: A: nr5a1 (homo sapiens) (aka nuclear receptor subfamily 5 group a member 1)
B: androgen receptor (rattus norvegicus) (aka androgen receptor)
C: ar (homo sapiens) (androgen receptor (homo sapiens)) (aka androgen receptor)
D: thra1 (homo sapiens) (aka nuclear receptor subfamily 1 group d member 1)
E: retinoid x receptor alpha (homo sapiens) (aka retinoid x receptor alpha)
F: None of the above. | C |
<Instruct>: Given the context 'The androgen receptor (AR) is a member of the steroid receptor superfamily that plays an important role in male sexual differentiation and prostate cell proliferation.', select the correct biomedical concept corresponding to 'androgen receptor'. Answer using one of the provided options. | <Options>: A: thra (homo sapiens) (aka thyroid hormone receptor alpha)
B: thra1 (homo sapiens) (aka nuclear receptor subfamily 1 group d member 1)
C: nr5a1 (homo sapiens) (aka nuclear receptor subfamily 5 group a member 1)
D: androgen receptor (rattus norvegicus) (aka androgen receptor)
E: retinoid x receptor alpha (homo sapiens) (aka retinoid x receptor alpha)
F: None of the above. | F |
<Instruct>: Given the context 'The androgen receptor (AR) is a member of the steroid receptor superfamily that plays an important role in male sexual differentiation and prostate cell proliferation.', select the correct biomedical concept corresponding to 'ar'. Answer using one of the provided options. | <Options>: A: ar (drosophila melanogaster) (defective in the avoidance of repellents (drosophila melanogaster)) (aka defective in the avoidance of repellents)
B: ar1 (homo sapiens) (aka transcription factor 20)
C: androgen receptor (homo sapiens) (aka androgen receptor)
D: androgen receptor repeat instability region (homo sapiens) (aka androgen receptor repeat instability region)
E: ar (rattus norvegicus) (androgen receptor (rattus norvegicus)) (aka androgen receptor)
F: None of the above. | C |
<Instruct>: Given the context 'Mutations or abnormal expression of AR in prostate cancer can play a key role in the process that changes prostate cancer from androgen-dependent to an androgen-independent stage.', select the correct biomedical concept corresponding to 'ar'. Answer using one of the provided options. | <Options>: A: ar (rattus norvegicus) (androgen receptor (rattus norvegicus)) (aka androgen receptor)
B: ar1 (arabidopsis thaliana) (aka p450 reductase 1)
C: ar (drosophila melanogaster) (defective in the avoidance of repellents (drosophila melanogaster)) (aka defective in the avoidance of repellents)
D: ar (homo sapiens) (androgen receptor (homo sapiens)) (aka androgen receptor)
E: androgen receptor repeat instability region (homo sapiens) (aka androgen receptor repeat instability region)
F: None of the above. | D |
<Instruct>: Given the context 'Using a yeast two-hybrid system, we were able to isolate a ligand-dependent AR-associated protein (ARA70), which functions as an activator to enhance AR transcriptional activity 10-fold in the presence of 10(-10)', select the correct biomedical concept corresponding to 'ligand-dependent ar-associated protein'. Answer using one of the provided options. | <Options>: A: angiotensin ii receptor associated protein (homo sapiens) (aka angiotensin ii receptor associated protein)
B: transformation/transcription domain associated protein (homo sapiens) (aka transformation/transcription domain associated protein)
C: ligand of ate1 (homo sapiens) (aka ligand of ate1)
D: arl4ap5 (homo sapiens) (aka arf like gtpase 4a pseudogene 5)
E: serine-threonine kinase receptor-associated protein-like (homo sapiens) (aka serine-threonine kinase receptor-associated protein-like)
F: None of the above. | F |
<Instruct>: Given the context 'Using a yeast two-hybrid system, we were able to isolate a ligand-dependent AR-associated protein (ARA70), which functions as an activator to enhance AR transcriptional activity 10-fold in the presence of 10(-10)', select the correct biomedical concept corresponding to 'ara70'. Answer using one of the provided options. | <Options>: A: arc100 (homo sapiens) (aka mediator complex subunit 24)
B: ara70 (homo sapiens) (aka nuclear receptor coactivator 4)
C: ara70 (xenopus laevis) (nuclear receptor coactivator 4 s homeolog (xenopus laevis)) (aka nuclear receptor coactivator 4 s homeolog)
D: ara160 (homo sapiens) (aka tata element modulatory factor 1)
E: ra70 (homo sapiens) (aka src kinase associated phosphoprotein 2)
F: None of the above. | B |
<Instruct>: Given the context 'Using a yeast two-hybrid system, we were able to isolate a ligand-dependent AR-associated protein (ARA70), which functions as an activator to enhance AR transcriptional activity 10-fold in the presence of 10(-10)', select the correct biomedical concept corresponding to 'ar'. Answer using one of the provided options. | <Options>: A: ar (homo sapiens) (androgen receptor (homo sapiens)) (aka androgen receptor)
B: ager1 (homo sapiens) (aka dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit)
C: ar1 (homo sapiens) (aka transcription factor 20)
D: ar (drosophila melanogaster) (defective in the avoidance of repellents (drosophila melanogaster)) (aka defective in the avoidance of repellents)
E: anr1 (arabidopsis thaliana) (aka agamous-like 44)
F: None of the above. | A |
<Instruct>: Given the context 'Our data further indicated that ARA70 Will only slightly induce the transcriptional activity of other steroid receptors such as estrogen receptor, glucocorticoid receptor, and progesterone receptor in DU145 cells.', select the correct biomedical concept corresponding to 'ara70'. Answer using one of the provided options. | <Options>: A: ara70 (xenopus tropicalis) (aka nuclear receptor coactivator 4)
B: ara70 (homo sapiens) (aka nuclear receptor coactivator 4)
C: ara70 (xenopus laevis) (nuclear receptor coactivator 4 s homeolog (xenopus laevis)) (aka nuclear receptor coactivator 4 s homeolog)
D: ra70 (homo sapiens) (aka src kinase associated phosphoprotein 2)
E: rpa70 (homo sapiens) (aka replication protein a1)
F: None of the above. | B |
<Instruct>: Given the context 'Our data further indicated that ARA70 Will only slightly induce the transcriptional activity of other steroid receptors such as estrogen receptor, glucocorticoid receptor, and progesterone receptor in DU145 cells.', select the correct biomedical concept corresponding to 'glucocorticoid receptor'. Answer using one of the provided options. | <Options>: A: nr1c1 (homo sapiens) (aka peroxisome proliferator activated receptor alpha)
B: growth hormone secretagogue receptor (homo sapiens) (aka growth hormone secretagogue receptor)
C: growth hormone releasing hormone receptor (homo sapiens) (aka growth hormone releasing hormone receptor)
D: growth hormone receptor (homo sapiens) (aka growth hormone receptor)
E: nr3c1 (homo sapiens) (aka nuclear receptor subfamily 3 group c member 1)
F: None of the above. | E |
<Instruct>: Given the context 'Our data further indicated that ARA70 Will only slightly induce the transcriptional activity of other steroid receptors such as estrogen receptor, glucocorticoid receptor, and progesterone receptor in DU145 cells.', select the correct biomedical concept corresponding to 'progesterone receptor'. Answer using one of the provided options. | <Options>: A: progesterone receptor (gallus gallus) (aka progesterone receptor)
B: progesterone receptor (xenopus tropicalis) (aka progesterone receptor)
C: pgr (xenopus laevis) (progesterone receptor s homeolog (xenopus laevis)) (aka progesterone receptor s homeolog)
D: prlr (homo sapiens) (aka prolactin receptor)
E: pr (homo sapiens) (progesterone receptor (homo sapiens)) (aka progesterone receptor)
F: None of the above. | E |
<Instruct>: Given the context 'Together, these data suggest that AR may need a specific coactivator(s) such as ARA70 for optimal androgen activity.', select the correct biomedical concept corresponding to 'ar'. Answer using one of the provided options. | <Options>: A: ar (rattus norvegicus) (androgen receptor (rattus norvegicus)) (aka androgen receptor)
B: ar1 (arabidopsis thaliana) (aka p450 reductase 1)
C: ager1 (homo sapiens) (aka dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit)
D: ar (drosophila melanogaster) (defective in the avoidance of repellents (drosophila melanogaster)) (aka defective in the avoidance of repellents)
E: ar (homo sapiens) (androgen receptor (homo sapiens)) (aka androgen receptor)
F: None of the above. | E |
<Instruct>: Given the context 'Together, these data suggest that AR may need a specific coactivator(s) such as ARA70 for optimal androgen activity.', select the correct biomedical concept corresponding to 'ara70'. Answer using one of the provided options. | <Options>: A: ara70 (homo sapiens) (aka nuclear receptor coactivator 4)
B: ara70 (xenopus tropicalis) (aka nuclear receptor coactivator 4)
C: ara70 (mus musculus) (aka nuclear receptor coactivator 4)
D: rpa70 (xenopus laevis) (replication protein a1 s homeolog (xenopus laevis)) (aka replication protein a1 s homeolog)
E: rpa70 (homo sapiens) (aka replication protein a1)
F: None of the above. | A |
<Instruct>: Given the context 'Together, these data suggest that AR may need a specific coactivator(s) such as ARA70 for optimal androgen activity.', select the correct biomedical concept corresponding to 'ara70'. Answer using one of the provided options. | <Options>: A: ra70 (homo sapiens) (aka src kinase associated phosphoprotein 2)
B: ara70 (mus musculus) (aka nuclear receptor coactivator 4)
C: crsp70 (homo sapiens) (aka mediator complex subunit 26)
D: rpa70 (homo sapiens) (aka replication protein a1)
E: ara160 (homo sapiens) (aka tata element modulatory factor 1)
F: None of the above. | F |
<Instruct>: Given the context 'Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family.
', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: evi5 (homo sapiens) (aka ecotropic viral integration site 5)
B: evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis)) (aka mds1 and evi1 complex locus)
C: mds1-evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
D: ev1 (homo sapiens) (aka transmembrane channel like 6)
E: eve-1 (homo sapiens) (aka sh3 domain containing 19)
F: None of the above. | C |
<Instruct>: Given the context 'The EVI1 gene, located at chromosome band 3q26, is overexpressed in some myeloid leukemia patients with breakpoints either 5' of the gene in the t(3;3)(q21;q26) or 3' of the gene in the inv(3)(q21q26).', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: evi3 (homo sapiens) (aka zinc finger protein 521)
B: evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
C: ev1 (homo sapiens) (aka transmembrane channel like 6)
D: evi (homo sapiens) (aka wnt ligand secretion mediator)
E: evi-1 (homo sapiens) (aka runx family transcription factor 1)
F: None of the above. | B |
<Instruct>: Given the context 'EVI1 is also expressed as part of a fusion transcript with the transcription factor AML1 in the t(3;21)(q26;q22), associated with myeloid leukemia.', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: evi (homo sapiens) (aka wnt ligand secretion mediator)
B: evi5 (homo sapiens) (aka ecotropic viral integration site 5)
C: evi-1 (homo sapiens) (aka runx family transcription factor 1)
D: mds1-evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
E: evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis)) (aka mds1 and evi1 complex locus)
F: None of the above. | D |
<Instruct>: Given the context 'EVI1 is also expressed as part of a fusion transcript with the transcription factor AML1 in the t(3;21)(q26;q22), associated with myeloid leukemia.', select the correct biomedical concept corresponding to 'aml1'. Answer using one of the provided options. | <Options>: A: aml2 (homo sapiens) (aka runx family transcription factor 3)
B: aml1 (homo sapiens) (aka runx family transcription factor 1)
C: aml-1 (xenopus tropicalis) (aka runx family transcription factor 1)
D: af1 (homo sapiens) (aka ephrin a5)
E: cbf1 (homo sapiens) (aka recombination signal binding protein for immunoglobulin kappa j region)
F: None of the above. | B |
<Instruct>: Given the context 'In cells with t(3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1.', select the correct biomedical concept corresponding to 'aml1'. Answer using one of the provided options. | <Options>: A: cbf-1 (homo sapiens) (aka recombination signal binding protein for immunoglobulin kappa j region)
B: af1 (homo sapiens) (aka ephrin a5)
C: aml-1 (xenopus tropicalis) (aka runx family transcription factor 1)
D: aml1 (homo sapiens) (aka runx family transcription factor 1)
E: aml3 (homo sapiens) (aka runx family transcription factor 2)
F: None of the above. | D |
<Instruct>: Given the context 'In cells with t(3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1.', select the correct biomedical concept corresponding to 'aml1'. Answer using one of the provided options. | <Options>: A: aml1 (homo sapiens) (aka runx family transcription factor 1)
B: aml2 (homo sapiens) (aka runx family transcription factor 3)
C: af1 (homo sapiens) (aka ephrin a5)
D: aml1t1 (homo sapiens) (aka runx1 partner transcriptional co-repressor 1)
E: aml-1 (xenopus tropicalis) (aka runx family transcription factor 1)
F: None of the above. | A |
<Instruct>: Given the context 'In cells with t(3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1.', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: mds1-evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
B: eve-1 (homo sapiens) (aka sh3 domain containing 19)
C: evi-1 (homo sapiens) (aka runx family transcription factor 1)
D: evi3 (homo sapiens) (aka zinc finger protein 521)
E: evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis)) (aka mds1 and evi1 complex locus)
F: None of the above. | A |
<Instruct>: Given the context 'MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped.', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis)) (aka mds1 and evi1 complex locus)
B: evi5 (homo sapiens) (aka ecotropic viral integration site 5)
C: evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
D: evi-1 (homo sapiens) (aka runx family transcription factor 1)
E: evi3 (homo sapiens) (aka zinc finger protein 521)
F: None of the above. | C |
<Instruct>: Given the context 'MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped.', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
B: evi3 (homo sapiens) (aka zinc finger protein 521)
C: evi-1 (homo sapiens) (aka runx family transcription factor 1)
D: evi5 (homo sapiens) (aka ecotropic viral integration site 5)
E: ev1 (homo sapiens) (aka transmembrane channel like 6)
F: None of the above. | A |
<Instruct>: Given the context 'MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1 We have analyzed the relationship between MDS1 and EVI1 to determine whether they are two separate genes.', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis)) (aka mds1 and evi1 complex locus)
B: evi-1 (homo sapiens) (aka runx family transcription factor 1)
C: mds1-evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
D: eve-1 (homo sapiens) (aka sh3 domain containing 19)
E: evi (homo sapiens) (aka wnt ligand secretion mediator)
F: None of the above. | C |
<Instruct>: Given the context 'MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1 We have analyzed the relationship between MDS1 and EVI1 to determine whether they are two separate genes.', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: evin1 (homo sapiens) (aka transmembrane channel like 6)
B: evi (homo sapiens) (aka wnt ligand secretion mediator)
C: evi5 (homo sapiens) (aka ecotropic viral integration site 5)
D: evi3 (homo sapiens) (aka zinc finger protein 521)
E: evi-1 (homo sapiens) (aka runx family transcription factor 1)
F: None of the above. | F |
<Instruct>: Given the context 'MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1 We have analyzed the relationship between MDS1 and EVI1 to determine whether they are two separate genes.', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: mds1-evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
B: evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis)) (aka mds1 and evi1 complex locus)
C: evi-1 (homo sapiens) (aka runx family transcription factor 1)
D: ev1 (homo sapiens) (aka transmembrane channel like 6)
E: eve-1 (homo sapiens) (aka sh3 domain containing 19)
F: None of the above. | A |
<Instruct>: Given the context 'In this report, we present evidence indicating that MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame.', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
B: evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis)) (aka mds1 and evi1 complex locus)
C: eve-1 (homo sapiens) (aka sh3 domain containing 19)
D: evi (homo sapiens) (aka wnt ligand secretion mediator)
E: evi5 (homo sapiens) (aka ecotropic viral integration site 5)
F: None of the above. | A |
<Instruct>: Given the context 'In this report, we present evidence indicating that MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame.', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: ev1 (homo sapiens) (aka transmembrane channel like 6)
B: evi5 (homo sapiens) (aka ecotropic viral integration site 5)
C: evi-1 (xenopus tropicalis) (mds1 and evi1 complex locus (xenopus tropicalis)) (aka mds1 and evi1 complex locus)
D: mds1-evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
E: evi-1 (homo sapiens) (aka runx family transcription factor 1)
F: None of the above. | D |
<Instruct>: Given the context 'This additional region has about 40% homology at the amino acid level with the PR domain of the retinoblastoma-interacting zinc-finger protein RIZ.', select the correct biomedical concept corresponding to 'retinoblastoma-interacting zinc-finger protein riz'. Answer using one of the provided options. | <Options>: A: riz (xenopus tropicalis) (aka pr domain containing 2, with znf domain)
B: rb associated krab zinc finger (homo sapiens) (aka rb associated krab zinc finger)
C: cdkn1a interacting zinc finger protein 1 (homo sapiens) (aka cdkn1a interacting zinc finger protein 1)
D: riaz (homo sapiens) (aka poz/btb and at hook containing zinc finger 1)
E: riz2 (homo sapiens) (aka pr/set domain 2)
F: None of the above. | E |
<Instruct>: Given the context 'These results are important in view of the fact that EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.', select the correct biomedical concept corresponding to 'evi1'. Answer using one of the provided options. | <Options>: A: eve-1 (homo sapiens) (aka sh3 domain containing 19)
B: evi3 (homo sapiens) (aka zinc finger protein 521)
C: evi1 (homo sapiens) (aka mds1 and evi1 complex locus)
D: evi-1 (homo sapiens) (aka runx family transcription factor 1)
E: evin1 (homo sapiens) (aka transmembrane channel like 6)
F: None of the above. | C |
<Instruct>: Given the context 'MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.
', select the correct biomedical concept corresponding to 'mdc9'. Answer using one of the provided options. | <Options>: A: mda-9 (homo sapiens) (aka syndecan binding protein)
B: mdc9 (mus musculus) (aka adam metallopeptidase domain 9)
C: mdc-l (homo sapiens) (aka adam metallopeptidase domain 28)
D: disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans) (aka disintegrin and metalloproteinase domain-containing protein 10 homolog)
E: adam metallopeptidase domain 9 (homo sapiens) (aka adam metallopeptidase domain 9)
F: None of the above. | E |
<Instruct>: Given the context 'We have cloned and sequenced the mouse and human homologue of a widely expressed cellular disintegrin, which we have termed MDC9 (for metalloprotease/disintegrin/cysteine-rich protein 9).', select the correct biomedical concept corresponding to 'mdc9'. Answer using one of the provided options. | <Options>: A: mdc-l (homo sapiens) (aka adam metallopeptidase domain 28)
B: mdc15 (homo sapiens) (aka adam metallopeptidase domain 15)
C: disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans) (aka disintegrin and metalloproteinase domain-containing protein 10 homolog)
D: mdc9 (homo sapiens) (aka adam metallopeptidase domain 9)
E: adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens) (aka adam metallopeptidase with thrombospondin type 1 motif 9)
F: None of the above. | D |
<Instruct>: Given the context 'We have cloned and sequenced the mouse and human homologue of a widely expressed cellular disintegrin, which we have termed MDC9 (for metalloprotease/disintegrin/cysteine-rich protein 9).', select the correct biomedical concept corresponding to 'metalloprotease/disintegrin/cysteine-rich protein 9'. Answer using one of the provided options. | <Options>: A: adamts9 (homo sapiens) (aka adam metallopeptidase with thrombospondin type 1 motif 9)
B: disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans) (aka disintegrin and metalloproteinase domain-containing protein 10 homolog)
C: disintegrin and metalloproteinase domain-containing protein 9-like (gallus gallus) (aka disintegrin and metalloproteinase domain-containing protein 9-like)
D: cpamd9 (homo sapiens) (aka alpha-2-macroglobulin like 1)
E: mdc9 (homo sapiens) (aka adam metallopeptidase domain 9)
F: None of the above. | E |
<Instruct>: Given the context 'MDC9 contains several distinct protein domains: a signal sequence is followed by a prodomain and a domain with sequence similarity to snake venom metalloproteases, a disintegrin domain, a cysteine-rich region, an EGF repeat, a membrane anchor, and a cytoplasmic tail.', select the correct biomedical concept corresponding to 'mdc9'. Answer using one of the provided options. | <Options>: A: mdc-l (homo sapiens) (aka adam metallopeptidase domain 28)
B: mda-9 (homo sapiens) (aka syndecan binding protein)
C: adam9 (homo sapiens) (aka adam metallopeptidase domain 9)
D: mdc-3 (homo sapiens) (aka adam metallopeptidase domain 23)
E: disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans) (aka disintegrin and metalloproteinase domain-containing protein 10 homolog)
F: None of the above. | C |
<Instruct>: Given the context 'The cytoplasmic tail of MDC9 has two proline-rich sequences which can bind the SH3 domain of Src, and may therefore function as SH3 ligand domains.', select the correct biomedical concept corresponding to 'mdc9'. Answer using one of the provided options. | <Options>: A: disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans) (aka disintegrin and metalloproteinase domain-containing protein 10 homolog)
B: mdc-3 (homo sapiens) (aka adam metallopeptidase domain 23)
C: mda-9 (homo sapiens) (aka syndecan binding protein)
D: mdc-l (homo sapiens) (aka adam metallopeptidase domain 28)
E: mdc9 (homo sapiens) (aka adam metallopeptidase domain 9)
F: None of the above. | E |
<Instruct>: Given the context 'The cytoplasmic tail of MDC9 has two proline-rich sequences which can bind the SH3 domain of Src, and may therefore function as SH3 ligand domains.', select the correct biomedical concept corresponding to 'mdc9'. Answer using one of the provided options. | <Options>: A: mdc9 (mus musculus) (aka adam metallopeptidase domain 9)
B: mda-9 (homo sapiens) (aka syndecan binding protein)
C: adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens) (aka adam metallopeptidase with thrombospondin type 1 motif 9)
D: mdc-3 (homo sapiens) (aka adam metallopeptidase domain 23)
E: mdc-l (homo sapiens) (aka adam metallopeptidase domain 28)
F: None of the above. | F |
<Instruct>: Given the context 'The cytoplasmic tail of MDC9 has two proline-rich sequences which can bind the SH3 domain of Src, and may therefore function as SH3 ligand domains.', select the correct biomedical concept corresponding to 'src'. Answer using one of the provided options. | <Options>: A: src (homo sapiens) (aka src proto-oncogene, non-receptor tyrosine kinase)
B: c-src2 (homo sapiens) (aka fgr proto-oncogene, src family tyrosine kinase)
C: src3 (homo sapiens) (aka nuclear receptor coactivator 3)
D: src1 (homo sapiens) (aka nuclear receptor coactivator 1)
E: src (sus scrofa) (aka src proto-oncogene, non-receptor tyrosine kinase)
F: None of the above. | A |
<Instruct>: Given the context 'Western blot analysis shows that MDC9 is an approximately 84-kD glycoprotein in all mouse tissues examined, and in NIH 3T3 fibroblast and C2C12 myoblast mouse cell lines.', select the correct biomedical concept corresponding to 'mdc9'. Answer using one of the provided options. | <Options>: A: adam metallopeptidase with thrombospondin type 1 motif 9 (homo sapiens) (aka adam metallopeptidase with thrombospondin type 1 motif 9)
B: disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans) (aka disintegrin and metalloproteinase domain-containing protein 10 homolog)
C: mdc15 (homo sapiens) (aka adam metallopeptidase domain 15)
D: mdc9 (mus musculus) (aka adam metallopeptidase domain 9)
E: adam metallopeptidase domain 9 (homo sapiens) (aka adam metallopeptidase domain 9)
F: None of the above. | E |
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