instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'Contrarily, the alpha1A channel with NP (alpha1A(+NP)), corresponding to Q-type channel, with 28 polyglutamines exhibited a positive shift of 5 mV. These results suggest that altered function of alpha1A(-NP) may contribute to degeneration of Purkinje cells, which express predominantly alpha1A(-NP), due to the reduced Ca(2+) influx resulting from the negative shift of voltage-dependent inactivation.', select the correct biomedical concept corresponding to 'alpha1a'. Answer using one of the provided options. | <Options>: A: hemoglobin subunit alpha 1 (homo sapiens) (aka hemoglobin subunit alpha 1)
B: alpha1 (homo sapiens) (aka adrenoceptor alpha 1d)
C: integrin subunit alpha 1 (homo sapiens) (aka integrin subunit alpha 1)
D: calcium voltage-gated channel subunit alpha1 a (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
E: amylase alpha 1a (homo sapiens) (aka amylase alpha 1a)
F: None of the above. | D |
<Instruct>: Given the context 'Contrarily, the alpha1A channel with NP (alpha1A(+NP)), corresponding to Q-type channel, with 28 polyglutamines exhibited a positive shift of 5 mV. These results suggest that altered function of alpha1A(-NP) may contribute to degeneration of Purkinje cells, which express predominantly alpha1A(-NP), due to the reduced Ca(2+) influx resulting from the negative shift of voltage-dependent inactivation.', select the correct biomedical concept corresponding to 'alpha1a'. Answer using one of the provided options. | <Options>: A: alpha1aar (homo sapiens) (aka adrenoceptor alpha 1a)
B: alpha1 (homo sapiens) (aka adrenoceptor alpha 1d)
C: integrin subunit alpha 1 (homo sapiens) (aka integrin subunit alpha 1)
D: amylase alpha 1a (homo sapiens) (aka amylase alpha 1a)
E: calcium voltage-gated channel subunit alpha1 i (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 i)
F: None of the above. | F |
<Instruct>: Given the context 'Contrarily, the alpha1A channel with NP (alpha1A(+NP)), corresponding to Q-type channel, with 28 polyglutamines exhibited a positive shift of 5 mV. These results suggest that altered function of alpha1A(-NP) may contribute to degeneration of Purkinje cells, which express predominantly alpha1A(-NP), due to the reduced Ca(2+) influx resulting from the negative shift of voltage-dependent inactivation.', select the correct biomedical concept corresponding to 'alpha1a'. Answer using one of the provided options. | <Options>: A: calcium voltage-gated channel subunit alpha1 a (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
B: calcium voltage-gated channel subunit alpha1 i (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 i)
C: alpha1aar (homo sapiens) (aka adrenoceptor alpha 1a)
D: hemoglobin subunit alpha 1 (homo sapiens) (aka hemoglobin subunit alpha 1)
E: a1a (homo sapiens) (aka serpin family a member 1)
F: None of the above. | A |
<Instruct>: Given the context 'Contrarily, the alpha1A channel with NP (alpha1A(+NP)), corresponding to Q-type channel, with 28 polyglutamines exhibited a positive shift of 5 mV. These results suggest that altered function of alpha1A(-NP) may contribute to degeneration of Purkinje cells, which express predominantly alpha1A(-NP), due to the reduced Ca(2+) influx resulting from the negative shift of voltage-dependent inactivation.', select the correct biomedical concept corresponding to 'alpha1a'. Answer using one of the provided options. | <Options>: A: hemoglobin subunit alpha 1 (homo sapiens) (aka hemoglobin subunit alpha 1)
B: calcium voltage-gated channel subunit alpha1 a (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
C: integrin subunit alpha 1 (homo sapiens) (aka integrin subunit alpha 1)
D: a1a (homo sapiens) (aka serpin family a member 1)
E: alpha1aar (homo sapiens) (aka adrenoceptor alpha 1a)
F: None of the above. | B |
<Instruct>: Given the context 'On the other hand, other types of neurons, expressing both alpha1A(-NP) and alpha1A(+NP), may survive because the positive shift of voltage-dependent inactivation of alpha1A(+NP) compensates Ca(2+) influx.', select the correct biomedical concept corresponding to 'alpha1a'. Answer using one of the provided options. | <Options>: A: calcium voltage-gated channel subunit alpha1 a (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
B: adra1a (homo sapiens) (adrenoceptor alpha 1a (homo sapiens)) (aka adrenoceptor alpha 1a)
C: alpha1 (homo sapiens) (aka adrenoceptor alpha 1d)
D: integrin subunit alpha 1 (homo sapiens) (aka integrin subunit alpha 1)
E: a1a (homo sapiens) (aka serpin family a member 1)
F: None of the above. | A |
<Instruct>: Given the context 'On the other hand, other types of neurons, expressing both alpha1A(-NP) and alpha1A(+NP), may survive because the positive shift of voltage-dependent inactivation of alpha1A(+NP) compensates Ca(2+) influx.', select the correct biomedical concept corresponding to 'alpha1a'. Answer using one of the provided options. | <Options>: A: hemoglobin subunit alpha 1 (homo sapiens) (aka hemoglobin subunit alpha 1)
B: tubulin alpha 1a (homo sapiens) (aka tubulin alpha 1a)
C: integrin subunit alpha 1 (homo sapiens) (aka integrin subunit alpha 1)
D: alpha1 (homo sapiens) (aka adrenoceptor alpha 1d)
E: calcium voltage-gated channel subunit alpha1 a (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
F: None of the above. | E |
<Instruct>: Given the context 'On the other hand, other types of neurons, expressing both alpha1A(-NP) and alpha1A(+NP), may survive because the positive shift of voltage-dependent inactivation of alpha1A(+NP) compensates Ca(2+) influx.', select the correct biomedical concept corresponding to 'alpha1a'. Answer using one of the provided options. | <Options>: A: a1a (homo sapiens) (aka serpin family a member 1)
B: amylase alpha 1a (homo sapiens) (aka amylase alpha 1a)
C: calcium voltage-gated channel subunit alpha1 a (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
D: integrin subunit alpha 1 (homo sapiens) (aka integrin subunit alpha 1)
E: hemoglobin subunit alpha 1 (homo sapiens) (aka hemoglobin subunit alpha 1)
F: None of the above. | C |
<Instruct>: Given the context 'Structure, mapping and expression of the human gene encoding the homeodomain protein, SIX2.
', select the correct biomedical concept corresponding to 'six2'. Answer using one of the provided options. | <Options>: A: six2 (homo sapiens) (aka six homeobox 2)
B: six2 (mus musculus) (aka sine oculis-related homeobox 2)
C: six4 (homo sapiens) (aka six homeobox 4)
D: six3 (homo sapiens) (aka six homeobox 3)
E: hairy and enhancer of split 5, gene 2 (xenopus tropicalis) (aka hairy and enhancer of split 5, gene 2)
F: None of the above. | A |
<Instruct>: Given the context 'Vertebrate genes with sequence similarity to the Drosophila homeobox gene, sine oculis (so), constitute the SIX family.', select the correct biomedical concept corresponding to 'sine oculis'. Answer using one of the provided options. | <Options>: A: dood (homo sapiens) (aka atpase h+ transporting v1 subunit b2)
B: otx (drosophila melanogaster) (aka ocelliless)
C: sine oculis (drosophila melanogaster) (aka sine oculis)
D: oculus-parvus (drosophila melanogaster) (aka oculus parvus)
E: otxa (xenopus laevis) (orthodenticle homeobox 2 s homeolog (xenopus laevis)) (aka orthodenticle homeobox 2 s homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'Vertebrate genes with sequence similarity to the Drosophila homeobox gene, sine oculis (so), constitute the SIX family.', select the correct biomedical concept corresponding to 'so'. Answer using one of the provided options. | <Options>: A: soga (homo sapiens) (aka microtubule crosslinking factor 2)
B: sok1 (homo sapiens) (aka serine/threonine kinase 25)
C: soho (danio rerio) (aka h6 family homeobox 4)
D: soh1 (homo sapiens) (aka mediator complex subunit 31)
E: so (drosophila melanogaster) (aka sine oculis)
F: None of the above. | E |
<Instruct>: Given the context 'Mutations in three of these genes in man (SIX5, SIX6 and SIX3) are associated with severe phenotypes, and therefore, the cloning of other human genes from this family is of interest.', select the correct biomedical concept corresponding to 'six5'. Answer using one of the provided options. | <Options>: A: hairy and enhancer of split 5 gene 5 (xenopus tropicalis) (aka hairy and enhancer of split 5 gene 5)
B: six6 (homo sapiens) (aka six homeobox 6)
C: six5 (mus musculus) (aka sine oculis-related homeobox 5)
D: six homeobox 5 (homo sapiens) (aka six homeobox 5)
E: six5 (gallus gallus) (aka six homeobox 5)
F: None of the above. | D |
<Instruct>: Given the context 'Mutations in three of these genes in man (SIX5, SIX6 and SIX3) are associated with severe phenotypes, and therefore, the cloning of other human genes from this family is of interest.', select the correct biomedical concept corresponding to 'six6'. Answer using one of the provided options. | <Options>: A: hoxa6 (homo sapiens) (aka homeobox a6)
B: paired box protein 6 homolog (caenorhabditis elegans) (aka paired box protein 6 homolog)
C: enhancer of seven in absentia 6 (drosophila melanogaster) (aka enhancer of seven in absentia 6)
D: six6 (homo sapiens) (aka six homeobox 6)
E: six6 (xenopus tropicalis) (aka six homeobox 6)
F: None of the above. | D |
<Instruct>: Given the context 'Mutations in three of these genes in man (SIX5, SIX6 and SIX3) are associated with severe phenotypes, and therefore, the cloning of other human genes from this family is of interest.', select the correct biomedical concept corresponding to 'six6'. Answer using one of the provided options. | <Options>: A: enhancer of seven in absentia 6 (drosophila melanogaster) (aka enhancer of seven in absentia 6)
B: six5 (homo sapiens) (aka six homeobox 5)
C: hoxa6 (homo sapiens) (aka homeobox a6)
D: six homeobox 6 (xenopus tropicalis) (aka six homeobox 6)
E: six6 (xenopus laevis) (aka six homeobox 6 l homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Mutations in three of these genes in man (SIX5, SIX6 and SIX3) are associated with severe phenotypes, and therefore, the cloning of other human genes from this family is of interest.', select the correct biomedical concept corresponding to 'six3'. Answer using one of the provided options. | <Options>: A: enhancer of seven in absentia 3 (drosophila melanogaster) (aka enhancer of seven in absentia 3)
B: hairy and enhancer of split 3 (xenopus tropicalis) (aka hairy and enhancer of split 3)
C: six3 (xenopus tropicalis) (aka six homeobox 3)
D: six3 (homo sapiens) (aka six homeobox 3)
E: six3 (gallus gallus) (aka six homeobox 3)
F: None of the above. | D |
<Instruct>: Given the context 'We have cloned and characterised the gene that encodes human SIX2, elucidated its gene structure and conducted expression studies in a range of tissues.', select the correct biomedical concept corresponding to 'six2'. Answer using one of the provided options. | <Options>: A: six2 (mus musculus) (aka sine oculis-related homeobox 2)
B: six2 (xenopus tropicalis) (aka six homeobox 2)
C: six6 (homo sapiens) (aka six homeobox 6)
D: six homeobox 2 (homo sapiens) (aka six homeobox 2)
E: hairy and enhancer of split 5, gene 2 (xenopus tropicalis) (aka hairy and enhancer of split 5, gene 2)
F: None of the above. | D |
<Instruct>: Given the context 'SIX2 is widely expressed in the late first-trimester fetus, but has a limited range of expression sites in the adult.', select the correct biomedical concept corresponding to 'six2'. Answer using one of the provided options. | <Options>: A: six homeobox 2 (homo sapiens) (aka six homeobox 2)
B: six2 (gallus gallus) (aka six homeobox 2)
C: six4 (homo sapiens) (aka six homeobox 4)
D: hairy and enhancer of split 5, gene 2 (xenopus tropicalis) (aka hairy and enhancer of split 5, gene 2)
E: six2 (mus musculus) (aka sine oculis-related homeobox 2)
F: None of the above. | A |
<Instruct>: Given the context 'The expression pattern of SIX2 and its localisation to chromosome 2p15-p16 will be of use in assessing its candidacy in human developmental disorders.', select the correct biomedical concept corresponding to 'six2'. Answer using one of the provided options. | <Options>: A: six2 (gallus gallus) (aka six homeobox 2)
B: six2 (homo sapiens) (aka six homeobox 2)
C: six2 (xenopus tropicalis) (aka six homeobox 2)
D: six4 (homo sapiens) (aka six homeobox 4)
E: six6 (homo sapiens) (aka six homeobox 6)
F: None of the above. | B |
<Instruct>: Given the context 'Enhanced growth of MCF-7 breast cancer cells overexpressing parathyroid hormone-related peptide.
PTH-related peptide (PTHrP) is a secreted protein produced by breast cancer cells both in vivo and in vitro.', select the correct biomedical concept corresponding to 'parathyroid hormone-related peptide'. Answer using one of the provided options. | <Options>: A: hptp (homo sapiens) (aka protein tyrosine phosphatase receptor type d)
B: pthrp (homo sapiens) (aka parathyroid hormone like hormone)
C: parathyroid hormone-related protein-like (xenopus laevis) (aka parathyroid hormone-related protein-like)
D: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
E: pth promoter region (homo sapiens) (aka pth promoter region)
F: None of the above. | B |
<Instruct>: Given the context 'Enhanced growth of MCF-7 breast cancer cells overexpressing parathyroid hormone-related peptide.
PTH-related peptide (PTHrP) is a secreted protein produced by breast cancer cells both in vivo and in vitro.', select the correct biomedical concept corresponding to 'pth-related peptide'. Answer using one of the provided options. | <Options>: A: pth promoter region (homo sapiens) (aka pth promoter region)
B: pthrp (homo sapiens) (aka parathyroid hormone like hormone)
C: pro-trh (homo sapiens) (aka thyrotropin releasing hormone)
D: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
E: hptp (homo sapiens) (aka protein tyrosine phosphatase receptor type d)
F: None of the above. | B |
<Instruct>: Given the context 'Enhanced growth of MCF-7 breast cancer cells overexpressing parathyroid hormone-related peptide.
PTH-related peptide (PTHrP) is a secreted protein produced by breast cancer cells both in vivo and in vitro.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
B: pth promoter region (homo sapiens) (aka pth promoter region)
C: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
D: parathyroid hormone like hormone (homo sapiens) (aka parathyroid hormone like hormone)
E: pthr1 (homo sapiens) (aka parathyroid hormone 1 receptor)
F: None of the above. | D |
<Instruct>: Given the context 'Because of its structural similarity to PTH at the amino terminus, the two proteins interact with a common cell surface receptor, the PTH/PTHrP receptor.', select the correct biomedical concept corresponding to 'pth'. Answer using one of the provided options. | <Options>: A: hptp (homo sapiens) (aka protein tyrosine phosphatase receptor type d)
B: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
C: hpt (homo sapiens) (aka hypoparathyroidism)
D: parathyroid hormone like hormone (homo sapiens) (aka parathyroid hormone like hormone)
E: pth (homo sapiens) (parathyroid hormone (homo sapiens)) (aka parathyroid hormone)
F: None of the above. | E |
<Instruct>: Given the context 'Because of its structural similarity to PTH at the amino terminus, the two proteins interact with a common cell surface receptor, the PTH/PTHrP receptor.', select the correct biomedical concept corresponding to 'pth/pthrp receptor'. Answer using one of the provided options. | <Options>: A: parathyroid hormone 1 receptor (bos taurus) (aka parathyroid hormone 1 receptor)
B: thyrotropin releasing hormone receptor (homo sapiens) (aka thyrotropin releasing hormone receptor)
C: pth2r (homo sapiens) (aka parathyroid hormone 2 receptor)
D: pthr1 (homo sapiens) (aka parathyroid hormone 1 receptor)
E: None of the above. | D |
<Instruct>: Given the context 'When overproduced by tumor cells, PTHrP enters the circulation, giving rise to the common paraneoplastic syndrome of humoral hypercalcemia of malignancy.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pthr (homo sapiens) (parathyroid hormone 1 receptor (homo sapiens)) (aka parathyroid hormone 1 receptor)
B: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
C: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
D: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
E: parathyroid hormone like hormone (homo sapiens) (aka parathyroid hormone like hormone)
F: None of the above. | E |
<Instruct>: Given the context 'When overproduced by tumor cells, PTHrP enters the circulation, giving rise to the common paraneoplastic syndrome of humoral hypercalcemia of malignancy.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pthr1 (homo sapiens) (aka parathyroid hormone 1 receptor)
B: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
C: pthrp (bos taurus) (aka parathyroid hormone like hormone)
D: pth promoter region (homo sapiens) (aka pth promoter region)
E: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Although initially discovered in malignancies, PTHrP is now known to be produced by most cells and tissues in the body.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pthrp (bos taurus) (aka parathyroid hormone like hormone)
B: pth promoter region (homo sapiens) (aka pth promoter region)
C: pthr (homo sapiens) (parathyroid hormone like hormone (homo sapiens)) (aka parathyroid hormone like hormone)
D: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
E: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
F: None of the above. | C |
<Instruct>: Given the context 'It acts as an autocrine and paracrine mediator of cell proliferation and differentiation, effects which are mediated via the PTH/PTHrP receptor.', select the correct biomedical concept corresponding to 'pth/pthrp receptor'. Answer using one of the provided options. | <Options>: A: parathyroid hormone 2 receptor (homo sapiens) (aka parathyroid hormone 2 receptor)
B: pth1r (homo sapiens) (aka parathyroid hormone 1 receptor)
C: trhr (homo sapiens) (aka thyrotropin releasing hormone receptor)
D: parathyroid hormone 1 receptor (bos taurus) (aka parathyroid hormone 1 receptor)
E: None of the above. | B |
<Instruct>: Given the context 'Recent evidence also has shown that, directly after translation, PTHrP is able to enter the nucleus and/or nucleolus and influence cell cycle progression and apoptosis.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pth promoter region (homo sapiens) (aka pth promoter region)
B: pthr (homo sapiens) (parathyroid hormone like hormone (homo sapiens)) (aka parathyroid hormone like hormone)
C: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
D: pthr (homo sapiens) (parathyroid hormone 1 receptor (homo sapiens)) (aka parathyroid hormone 1 receptor)
E: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
F: None of the above. | B |
<Instruct>: Given the context 'In this study, we have either overproduced PTHrP or inhibited endogenous PTHrP production in the breast cancer cell line, MCF-7.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
B: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
C: pth promoter region (homo sapiens) (aka pth promoter region)
D: parathyroid hormone like hormone (homo sapiens) (aka parathyroid hormone like hormone)
E: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
F: None of the above. | D |
<Instruct>: Given the context 'In this study, we have either overproduced PTHrP or inhibited endogenous PTHrP production in the breast cancer cell line, MCF-7.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pthr (homo sapiens) (parathyroid hormone 1 receptor (homo sapiens)) (aka parathyroid hormone 1 receptor)
B: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
C: pthrp (homo sapiens) (aka parathyroid hormone like hormone)
D: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
E: pth promoter region (homo sapiens) (aka pth promoter region)
F: None of the above. | C |
<Instruct>: Given the context 'Overexpression of PTHrP was associated with an increase in mitogenesis, whereas inhibiting endogenous PTHrP production resulted in decreased cell proliferation.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
B: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
C: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
D: parathyroid hormone like hormone (homo sapiens) (aka parathyroid hormone like hormone)
E: pthr (homo sapiens) (parathyroid hormone 1 receptor (homo sapiens)) (aka parathyroid hormone 1 receptor)
F: None of the above. | D |
<Instruct>: Given the context 'Overexpression of PTHrP was associated with an increase in mitogenesis, whereas inhibiting endogenous PTHrP production resulted in decreased cell proliferation.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
B: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
C: pthr1 (homo sapiens) (aka parathyroid hormone 1 receptor)
D: pthrp (homo sapiens) (aka parathyroid hormone like hormone)
E: pthrp (bos taurus) (aka parathyroid hormone like hormone)
F: None of the above. | D |
<Instruct>: Given the context 'In contrast, PTHrP interaction with the cell surface PTH/PTHrP receptor resulted in decreased cell proliferation in the same cell line.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pth promoter region (homo sapiens) (aka pth promoter region)
B: pthrp (homo sapiens) (aka parathyroid hormone like hormone)
C: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
D: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
E: pthrp (bos taurus) (aka parathyroid hormone like hormone)
F: None of the above. | B |
<Instruct>: Given the context 'In contrast, PTHrP interaction with the cell surface PTH/PTHrP receptor resulted in decreased cell proliferation in the same cell line.', select the correct biomedical concept corresponding to 'pth/pthrp receptor'. Answer using one of the provided options. | <Options>: A: pthr1 (homo sapiens) (aka parathyroid hormone 1 receptor)
B: parathyroid hormone 2 receptor (homo sapiens) (aka parathyroid hormone 2 receptor)
C: parathyroid hormone 1 receptor (bos taurus) (aka parathyroid hormone 1 receptor)
D: trhr (homo sapiens) (aka thyrotropin releasing hormone receptor)
E: None of the above. | A |
<Instruct>: Given the context 'This latter effect is dependent on interaction with the receptor, in that exogenously added PTHrP moieties known not to interact with the receptor had no effect on cell growth.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
B: parathyroid hormone like hormone (homo sapiens) (aka parathyroid hormone like hormone)
C: pthr (homo sapiens) (parathyroid hormone 1 receptor (homo sapiens)) (aka parathyroid hormone 1 receptor)
D: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
E: pthrp (bos taurus) (aka parathyroid hormone like hormone)
F: None of the above. | B |
<Instruct>: Given the context 'This latter effect is dependent on interaction with the receptor, in that exogenously added PTHrP moieties known not to interact with the receptor had no effect on cell growth.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
B: pth promoter region (homo sapiens) (aka pth promoter region)
C: pthrp (bos taurus) (aka parathyroid hormone like hormone)
D: pthr (homo sapiens) (parathyroid hormone 1 receptor (homo sapiens)) (aka parathyroid hormone 1 receptor)
E: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Furthermore, neutralization of added peptide with an anti-PTHrP antiserum completely abolished the growth inhibitory effects.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pthrp (bos taurus) (aka parathyroid hormone like hormone)
B: pth promoter region (homo sapiens) (aka pth promoter region)
C: pthr (homo sapiens) (parathyroid hormone like hormone (homo sapiens)) (aka parathyroid hormone like hormone)
D: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
E: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'In contrast, this antibody has no effect on the increased proliferation rate of the MCF-7 transfectants that overexpress PTHrP, compared with control cells.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pthrp (bos taurus) (aka parathyroid hormone like hormone)
B: pth promoter region (homo sapiens) (aka pth promoter region)
C: pthrp (homo sapiens) (aka parathyroid hormone like hormone)
D: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
E: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
F: None of the above. | C |
<Instruct>: Given the context 'The net effect of autocrine/paracrine and intracrine effects of PTHrP in MCF-7 cells overproducing the peptide is accelerated cell growth.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pth promoter region (homo sapiens) (aka pth promoter region)
B: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
C: pthr (homo sapiens) (parathyroid hormone like hormone (homo sapiens)) (aka parathyroid hormone like hormone)
D: pthrp (bos taurus) (aka parathyroid hormone like hormone)
E: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'These findings have critical implications regarding the role of PTHrP in breast cancer, and they suggest that controlling PTHrP production in breast cancer may be useful therapeutically.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: pthrp (bos taurus) (aka parathyroid hormone like hormone)
B: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
C: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
D: parathyroid hormone like hormone (homo sapiens) (aka parathyroid hormone like hormone)
E: pth1 (homo sapiens) (aka peptidyl-trna hydrolase 1 homolog)
F: None of the above. | D |
<Instruct>: Given the context 'These findings have critical implications regarding the role of PTHrP in breast cancer, and they suggest that controlling PTHrP production in breast cancer may be useful therapeutically.', select the correct biomedical concept corresponding to 'pthrp'. Answer using one of the provided options. | <Options>: A: parathyroid hormone like hormone (homo sapiens) (aka parathyroid hormone like hormone)
B: pthr (homo sapiens) (parathyroid hormone 1 receptor (homo sapiens)) (aka parathyroid hormone 1 receptor)
C: pthrp (bos taurus) (aka parathyroid hormone like hormone)
D: parathyroid hormone (homo sapiens) (aka parathyroid hormone)
E: pthrp (xenopus laevis) (aka parathyroid hormone-like hormone l homeolog)
F: None of the above. | A |
<Instruct>: Given the context 'Intracellular parasitism by the human granulocytic ehrlichiosis bacterium through the P-selectin ligand, PSGL-1.
', select the correct biomedical concept corresponding to 'p-selectin ligand'. Answer using one of the provided options. | <Options>: A: selp (homo sapiens) (selectin p (homo sapiens)) (aka selectin p)
B: selectin l (homo sapiens) (aka selectin l)
C: selectin p ligand (sus scrofa) (aka selectin p ligand)
D: selectin e (homo sapiens) (aka selectin e)
E: selectin p ligand (homo sapiens) (aka selectin p ligand)
F: None of the above. | E |
<Instruct>: Given the context 'Intracellular parasitism by the human granulocytic ehrlichiosis bacterium through the P-selectin ligand, PSGL-1.
', select the correct biomedical concept corresponding to 'psgl-1'. Answer using one of the provided options. | <Options>: A: psg5 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 5)
B: psg3 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 3)
C: psbg-1 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 1)
D: psgl1 (homo sapiens) (aka selectin p ligand)
E: psg4 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 4)
F: None of the above. | D |
<Instruct>: Given the context 'Monoclonal antibodies against the P-selectin binding domain of the leukocyte P-selectin glycoprotein ligand, PSGL-1, prevented HGE cell binding and infection, as did enzymatic digestion of PSGL-1.', select the correct biomedical concept corresponding to 'p-selectin'. Answer using one of the provided options. | <Options>: A: selectin p (sus scrofa) (aka selectin p)
B: selectin p ligand (homo sapiens) (aka selectin p ligand)
C: selectin l (homo sapiens) (aka selectin l)
D: selp (homo sapiens) (selectin p (homo sapiens)) (aka selectin p)
E: selectin-e (homo sapiens) (aka selectin e)
F: None of the above. | D |
<Instruct>: Given the context 'Monoclonal antibodies against the P-selectin binding domain of the leukocyte P-selectin glycoprotein ligand, PSGL-1, prevented HGE cell binding and infection, as did enzymatic digestion of PSGL-1.', select the correct biomedical concept corresponding to 'p-selectin glycoprotein ligand'. Answer using one of the provided options. | <Options>: A: selectin-e (homo sapiens) (aka selectin e)
B: selectin p (sus scrofa) (aka selectin p)
C: selectin p ligand (sus scrofa) (aka selectin p ligand)
D: selectin p (homo sapiens) (aka selectin p)
E: selectin p ligand (homo sapiens) (aka selectin p ligand)
F: None of the above. | E |
<Instruct>: Given the context 'Monoclonal antibodies against the P-selectin binding domain of the leukocyte P-selectin glycoprotein ligand, PSGL-1, prevented HGE cell binding and infection, as did enzymatic digestion of PSGL-1.', select the correct biomedical concept corresponding to 'psgl-1'. Answer using one of the provided options. | <Options>: A: psg3 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 3)
B: psgl1 (homo sapiens) (aka selectin p ligand)
C: psg4 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 4)
D: psg1 (homo sapiens) (pregnancy specific beta-1-glycoprotein 7 (homo sapiens)) (aka pregnancy specific beta-1-glycoprotein 7)
E: psbg-1 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 1)
F: None of the above. | B |
<Instruct>: Given the context 'Monoclonal antibodies against the P-selectin binding domain of the leukocyte P-selectin glycoprotein ligand, PSGL-1, prevented HGE cell binding and infection, as did enzymatic digestion of PSGL-1.', select the correct biomedical concept corresponding to 'psgl-1'. Answer using one of the provided options. | <Options>: A: psg5 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 5)
B: psggb (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 6)
C: psg1 (homo sapiens) (pregnancy specific beta-1-glycoprotein 7 (homo sapiens)) (aka pregnancy specific beta-1-glycoprotein 7)
D: psbg-1 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 1)
E: psg3 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 3)
F: None of the above. | F |
<Instruct>: Given the context 'Monoclonal antibodies against the P-selectin binding domain of the leukocyte P-selectin glycoprotein ligand, PSGL-1, prevented HGE cell binding and infection, as did enzymatic digestion of PSGL-1.', select the correct biomedical concept corresponding to 'psgl-1'. Answer using one of the provided options. | <Options>: A: psgl1 (homo sapiens) (aka selectin p ligand)
B: psggb (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 6)
C: psgb-5-1 (homo sapiens) (aka cytochrome b5 type a pseudogene 3)
D: psg1 (homo sapiens) (pregnancy specific beta-1-glycoprotein 7 (homo sapiens)) (aka pregnancy specific beta-1-glycoprotein 7)
E: psbg-1 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 1)
F: None of the above. | A |
<Instruct>: Given the context 'Furthermore, simultaneous neoexpression in nonsusceptible cells of complementary DNAs for both PSGL-1 and its modifying alpha-(1,3) fucosyltransferase, Fuc-TVII, allowed binding and infection by HGE.', select the correct biomedical concept corresponding to 'psgl-1'. Answer using one of the provided options. | <Options>: A: psg5 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 5)
B: psgb-5-1 (homo sapiens) (aka cytochrome b5 type a pseudogene 3)
C: psgl-1 (homo sapiens) (aka selectin p ligand)
D: psg1 (homo sapiens) (pregnancy specific beta-1-glycoprotein 7 (homo sapiens)) (aka pregnancy specific beta-1-glycoprotein 7)
E: psg1 (homo sapiens) (pregnancy specific beta-1-glycoprotein 1 (homo sapiens)) (aka pregnancy specific beta-1-glycoprotein 1)
F: None of the above. | C |
<Instruct>: Given the context 'Furthermore, simultaneous neoexpression in nonsusceptible cells of complementary DNAs for both PSGL-1 and its modifying alpha-(1,3) fucosyltransferase, Fuc-TVII, allowed binding and infection by HGE.', select the correct biomedical concept corresponding to 'alpha-(1,3) fucosyltransferase'. Answer using one of the provided options. | <Options>: A: fuct1 (homo sapiens) (aka solute carrier family 35 member c1)
B: alpha-(1,3)-fucosyltransferase fut-1 (caenorhabditis elegans) (aka alpha-(1,3)-fucosyltransferase fut-1)
C: fucosyltransferase 10 (alpha (1,3) fucosyltransferase) (xenopus tropicalis) (aka fucosyltransferase 10 (alpha (1,3) fucosyltransferase))
D: fucosyltransferase 7 (homo sapiens) (aka fucosyltransferase 7)
E: alpha1,6-fucosyltransferase (drosophila melanogaster) (aka alpha1,6-fucosyltransferase)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, simultaneous neoexpression in nonsusceptible cells of complementary DNAs for both PSGL-1 and its modifying alpha-(1,3) fucosyltransferase, Fuc-TVII, allowed binding and infection by HGE.', select the correct biomedical concept corresponding to 'fuc-tvii'. Answer using one of the provided options. | <Options>: A: fuct-vii (homo sapiens) (aka fucosyltransferase 7)
B: fuc-tvi (homo sapiens) (aka fucosyltransferase 6)
C: fuct-iii (homo sapiens) (aka fucosyltransferase 3 (lewis blood group))
D: fuc-tvii (mus musculus) (aka fucosyltransferase 7)
E: fuct-vii (xenopus tropicalis) (aka fucosyltransferase 7 (alpha (1,3) fucosyltransferase))
F: None of the above. | A |
<Instruct>: Given the context 'Thus, the HGE bacterium specifically bound to fucosylated leukocyte PSGL-1.', select the correct biomedical concept corresponding to 'psgl-1'. Answer using one of the provided options. | <Options>: A: psg4 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 4)
B: psggb (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 6)
C: psgb-5-1 (homo sapiens) (aka cytochrome b5 type a pseudogene 3)
D: psgl-1 (homo sapiens) (aka selectin p ligand)
E: psg5 (homo sapiens) (aka pregnancy specific beta-1-glycoprotein 5)
F: None of the above. | D |
<Instruct>: Given the context '3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins.
', select the correct biomedical concept corresponding to '3-methyladenine-dna glycosylase'. Answer using one of the provided options. | <Options>: A: n-methylpurine-dna glycosylase (mus musculus) (aka n-methylpurine-dna glycosylase)
B: n-methylpurine dna glycosylase (homo sapiens) (aka n-methylpurine dna glycosylase)
C: thymine dna glycosylase (mus musculus) (aka thymine dna glycosylase)
D: 8-oxoguanine dna-glycosylase 1 (mus musculus) (aka 8-oxoguanine dna-glycosylase 1)
E: uracil dna glycosylase (mus musculus) (aka uracil dna glycosylase)
F: None of the above. | B |
<Instruct>: Given the context '3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins.
', select the correct biomedical concept corresponding to 'mpg'. Answer using one of the provided options. | <Options>: A: ppg (mus musculus) (aka glucagon)
B: mpg (oryctolagus cuniculus) (aka n-methylpurine dna glycosylase)
C: mpg1 (homo sapiens) (aka macrophage expressed 1)
D: mpg (homo sapiens) (aka n-methylpurine dna glycosylase)
E: mpg-1 (mus musculus) (aka macrophage expressed gene 1)
F: None of the above. | D |
<Instruct>: Given the context 'Human 3-methyladenine-DNA glycosylase (MPG protein) initiates base excision repair by severing the glycosylic bond of numerous damaged bases.', select the correct biomedical concept corresponding to '3-methyladenine-dna glycosylase'. Answer using one of the provided options. | <Options>: A: aag (mus musculus) (n-methylpurine-dna glycosylase (mus musculus)) (aka n-methylpurine-dna glycosylase)
B: n-methylpurine dna glycosylase (homo sapiens) (aka n-methylpurine dna glycosylase)
C: uracil dna glycosylase (mus musculus) (aka uracil dna glycosylase)
D: muty dna glycosylase (mus musculus) (aka muty dna glycosylase)
E: 8-oxoguanine dna-glycosylase 1 (mus musculus) (aka 8-oxoguanine dna-glycosylase 1)
F: None of the above. | B |
<Instruct>: Given the context 'Human 3-methyladenine-DNA glycosylase (MPG protein) initiates base excision repair by severing the glycosylic bond of numerous damaged bases.', select the correct biomedical concept corresponding to 'mpg'. Answer using one of the provided options. | <Options>: A: mgp (homo sapiens) (aka matrix gla protein)
B: mpg (mus musculus) (aka n-methylpurine-dna glycosylase)
C: mpg (homo sapiens) (aka n-methylpurine dna glycosylase)
D: mp (mus musculus) (aka micropinna microphthalmia)
E: ppg (mus musculus) (aka glucagon)
F: None of the above. | C |
<Instruct>: Given the context 'In comparison, homologues of the Rad23 proteins (hHR23) and the hXPC protein are involved in the recognition of damaged bases in global genome repair, a subset of nucleotide excision repair.', select the correct biomedical concept corresponding to 'hxpc'. Answer using one of the provided options. | <Options>: A: hypc (xenopus tropicalis) (aka pre-mrna processing factor 40 homolog a)
B: cphx (homo sapiens) (aka tmem254 antisense rna 1)
C: hcypx (homo sapiens) (aka peptidylprolyl isomerase like 1)
D: hppc (homo sapiens) (aka alkaline phosphatase, biomineralization associated)
E: hppcn (homo sapiens) (aka acidic nuclear phosphoprotein 32 family member a)
F: None of the above. | F |
<Instruct>: Given the context 'In comparison, homologues of the Rad23 proteins (hHR23) and the hXPC protein are involved in the recognition of damaged bases in global genome repair, a subset of nucleotide excision repair.', select the correct biomedical concept corresponding to 'hxpc'. Answer using one of the provided options. | <Options>: A: cphx (homo sapiens) (aka tmem254 antisense rna 1)
B: hppc (homo sapiens) (aka alkaline phosphatase, biomineralization associated)
C: hcypx (homo sapiens) (aka peptidylprolyl isomerase like 1)
D: humpcp (homo sapiens) (aka prolylcarboxypeptidase)
E: hcph (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 6)
F: None of the above. | F |
<Instruct>: Given the context 'In this report, we show that the hHR23A and -B also interact with the MPG protein and can serve as accessory proteins for DNA damage recognition in base excision repair.', select the correct biomedical concept corresponding to 'mpg'. Answer using one of the provided options. | <Options>: A: mp (mus musculus) (aka micropinna microphthalmia)
B: mpg (mus musculus) (aka n-methylpurine-dna glycosylase)
C: mpg (homo sapiens) (aka n-methylpurine dna glycosylase)
D: mgp (homo sapiens) (aka matrix gla protein)
E: mgp (mus musculus) (aka matrix gla protein)
F: None of the above. | C |
<Instruct>: Given the context 'Furthermore, the MPG.hHR23 protein complex elevates the rate of MPG protein-catalyzed excision from hypoxanthine-containing substrates.', select the correct biomedical concept corresponding to 'mpg'. Answer using one of the provided options. | <Options>: A: mpg-1 (mus musculus) (aka macrophage expressed gene 1)
B: mpg (mus musculus) (aka n-methylpurine-dna glycosylase)
C: mpg (homo sapiens) (aka n-methylpurine dna glycosylase)
D: mgp (homo sapiens) (aka matrix gla protein)
E: mpg (oryctolagus cuniculus) (aka n-methylpurine dna glycosylase)
F: None of the above. | C |
<Instruct>: Given the context 'Furthermore, the MPG.hHR23 protein complex elevates the rate of MPG protein-catalyzed excision from hypoxanthine-containing substrates.', select the correct biomedical concept corresponding to 'mpg'. Answer using one of the provided options. | <Options>: A: mp (mus musculus) (aka micropinna microphthalmia)
B: ppg (mus musculus) (aka glucagon)
C: mpg-1 (mus musculus) (aka macrophage expressed gene 1)
D: mpg (homo sapiens) (aka n-methylpurine dna glycosylase)
E: mpg-1 (homo sapiens) (aka macrophage expressed 1)
F: None of the above. | D |
<Instruct>: Given the context 'This increased excision rate is correlated with a greater binding affinity of the MPG protein-hHR23 protein complex for damaged DNA.', select the correct biomedical concept corresponding to 'mpg'. Answer using one of the provided options. | <Options>: A: mpg-1 (mus musculus) (aka macrophage expressed gene 1)
B: mgp (homo sapiens) (aka matrix gla protein)
C: mpg (homo sapiens) (aka n-methylpurine dna glycosylase)
D: mp (mus musculus) (aka micropinna microphthalmia)
E: mpg (mus musculus) (aka n-methylpurine-dna glycosylase)
F: None of the above. | C |
<Instruct>: Given the context 'Expression, purification, and functional analysis of the human serine protease HtrA2.
HumHtrA2 or Omi is a recently described member of a novel family of mammalian serine proteases homologous to the Escherichia coli htrA gene product.', select the correct biomedical concept corresponding to 'htra2'. Answer using one of the provided options. | <Options>: A: htra2-beta (homo sapiens) (aka transformer 2 beta homolog)
B: htra2 (sus scrofa) (aka htra serine peptidase 2)
C: htra serine peptidase 2 (mus musculus) (aka htra serine peptidase 2)
D: htr2 (homo sapiens) (aka 5-hydroxytryptamine receptor 2a)
E: htra serine peptidase 2 (homo sapiens) (aka htra serine peptidase 2)
F: None of the above. | E |
<Instruct>: Given the context 'Expression, purification, and functional analysis of the human serine protease HtrA2.
HumHtrA2 or Omi is a recently described member of a novel family of mammalian serine proteases homologous to the Escherichia coli htrA gene product.', select the correct biomedical concept corresponding to 'humhtra2'. Answer using one of the provided options. | <Options>: A: atoh2 (homo sapiens) (aka neuronal differentiation 6)
B: thrap2 (homo sapiens) (aka mediator complex subunit 13l)
C: arb2a (homo sapiens) (aka arb2 cotranscriptional regulator a)
D: hthtr2 (homo sapiens) (aka solute carrier family 19 member 3)
E: mxra2 (homo sapiens) (aka parvin alpha)
F: None of the above. | F |
<Instruct>: Given the context 'Expression, purification, and functional analysis of the human serine protease HtrA2.
HumHtrA2 or Omi is a recently described member of a novel family of mammalian serine proteases homologous to the Escherichia coli htrA gene product.', select the correct biomedical concept corresponding to 'omi'. Answer using one of the provided options. | <Options>: A: omi (homo sapiens) (aka htra serine peptidase 2)
B: om-1 (mus musculus) (aka importin 8)
C: omi (mus musculus) (aka htra serine peptidase 2)
D: ommatidialess (drosophila melanogaster) (aka ommatidialess)
E: om (drosophila melanogaster) (aka ommatidia)
F: None of the above. | A |
<Instruct>: Given the context 'In this report we describe the overexpression of humHtrA2 in two heterologous systems comparing the merits of each.', select the correct biomedical concept corresponding to 'humhtra2'. Answer using one of the provided options. | <Options>: A: mxra2 (homo sapiens) (aka parvin alpha)
B: thrap2 (homo sapiens) (aka mediator complex subunit 13l)
C: hthtr2 (homo sapiens) (aka solute carrier family 19 member 3)
D: tra2a (homo sapiens) (aka transformer 2 alpha homolog)
E: atoh2 (homo sapiens) (aka neuronal differentiation 6)
F: None of the above. | F |
<Instruct>: Given the context 'By means of fluorescently labeled substrates alpha- and beta-casein and zymography, the proteolytic activity of recombinant HumHtrA2 was also demonstrated.', select the correct biomedical concept corresponding to 'humhtra2'. Answer using one of the provided options. | <Options>: A: htpcr2 (homo sapiens) (aka olfactory receptor family 7 subfamily a member 5)
B: thralpha2 (homo sapiens) (aka thyroid hormone receptor alpha)
C: thrap2 (homo sapiens) (aka mediator complex subunit 13l)
D: tra2a (homo sapiens) (aka transformer 2 alpha homolog)
E: mxra2 (homo sapiens) (aka parvin alpha)
F: None of the above. | F |
<Instruct>: Given the context 'Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein.
IL-2 is the major autocrine and paracrine growth factor produced by T cells upon T cell stimulation.', select the correct biomedical concept corresponding to 'il-2'. Answer using one of the provided options. | <Options>: A: csf2 (homo sapiens) (aka colony stimulating factor 2)
B: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
C: ilf2 (homo sapiens) (aka interleukin enhancer binding factor 2)
D: il22 (homo sapiens) (aka interleukin 22)
E: il2 (homo sapiens) (aka interleukin 2)
F: None of the above. | E |
<Instruct>: Given the context 'Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein.
IL-2 is the major autocrine and paracrine growth factor produced by T cells upon T cell stimulation.', select the correct biomedical concept corresponding to 'il-2'. Answer using one of the provided options. | <Options>: A: interleukin 3 (homo sapiens) (aka interleukin 3)
B: colony stimulating factor 2 (homo sapiens) (aka colony stimulating factor 2)
C: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
D: interleukin enhancer binding factor 2 (homo sapiens) (aka interleukin enhancer binding factor 2)
E: il22 (homo sapiens) (aka interleukin 22)
F: None of the above. | F |
<Instruct>: Given the context 'Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein.
IL-2 is the major autocrine and paracrine growth factor produced by T cells upon T cell stimulation.', select the correct biomedical concept corresponding to 'p21snft'. Answer using one of the provided options. | <Options>: A: hsnfs (homo sapiens) (aka swi/snf related baf chromatin remodeling complex subunit b1)
B: ntf2 (saccharomyces cerevisiae s288c) (aka ran gtpase-binding protein ntf2)
C: rft1 homolog (rattus norvegicus) (aka rft1 homolog)
D: snft (homo sapiens) (aka basic leucine zipper atf-like transcription factor 3)
E: nst1 (saccharomyces cerevisiae s288c) (aka nst1p)
F: None of the above. | D |
<Instruct>: Given the context 'Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein.
IL-2 is the major autocrine and paracrine growth factor produced by T cells upon T cell stimulation.', select the correct biomedical concept corresponding to 'il-2'. Answer using one of the provided options. | <Options>: A: colony stimulating factor 2 (homo sapiens) (aka colony stimulating factor 2)
B: il22 (homo sapiens) (aka interleukin 22)
C: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
D: ilf2 (homo sapiens) (aka interleukin enhancer binding factor 2)
E: il-2 (homo sapiens) (aka interleukin 2)
F: None of the above. | E |
<Instruct>: Given the context 'The inducible expression of IL-2 is highly regulated by multiple transcription factors, particularly AP-1, which coordinately activate the promoter.', select the correct biomedical concept corresponding to 'il-2'. Answer using one of the provided options. | <Options>: A: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
B: il22 (homo sapiens) (aka interleukin 22)
C: csf2 (homo sapiens) (aka colony stimulating factor 2)
D: interleukin 3 (homo sapiens) (aka interleukin 3)
E: il-2 (homo sapiens) (aka interleukin 2)
F: None of the above. | E |
<Instruct>: Given the context 'Described here is the ability of the novel basic leucine zipper protein p21SNFT to repress AP-1 activity and IL-2 transcription.', select the correct biomedical concept corresponding to 'p21snft'. Answer using one of the provided options. | <Options>: A: snft (homo sapiens) (aka basic leucine zipper atf-like transcription factor 3)
B: putative multidrug transporter nft1 (saccharomyces cerevisiae s288c) (aka putative multidrug transporter nft1)
C: ntf2 (saccharomyces cerevisiae s288c) (aka ran gtpase-binding protein ntf2)
D: cstf2t (homo sapiens) (aka cleavage stimulation factor subunit 2 tau variant)
E: nst1 (saccharomyces cerevisiae s288c) (aka nst1p)
F: None of the above. | A |
<Instruct>: Given the context 'Described here is the ability of the novel basic leucine zipper protein p21SNFT to repress AP-1 activity and IL-2 transcription.', select the correct biomedical concept corresponding to 'il-2'. Answer using one of the provided options. | <Options>: A: il2 (homo sapiens) (aka interleukin 2)
B: csf2 (homo sapiens) (aka colony stimulating factor 2)
C: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
D: il22 (homo sapiens) (aka interleukin 22)
E: ilf2 (homo sapiens) (aka interleukin enhancer binding factor 2)
F: None of the above. | A |
<Instruct>: Given the context 'A detailed analysis of the repression by p21SNFT repression on the IL-2 promoter distal NF-AT/AP-1 site demonstrates that it can bind DNA with NF-AT and Jun, strongly suggesting that it represses NF-AT/AP-1 activity by competing with Fos proteins for Jun dimerization.', select the correct biomedical concept corresponding to 'p21snft'. Answer using one of the provided options. | <Options>: A: rft1 homolog (rattus norvegicus) (aka rft1 homolog)
B: hsnfs (homo sapiens) (aka swi/snf related baf chromatin remodeling complex subunit b1)
C: nft1 (saccharomyces cerevisiae s288c) (uncharacterized protein (saccharomyces cerevisiae s288c)) (aka uncharacterized protein)
D: putative multidrug transporter nft1 (saccharomyces cerevisiae s288c) (aka putative multidrug transporter nft1)
E: snft (homo sapiens) (aka basic leucine zipper atf-like transcription factor 3)
F: None of the above. | E |
<Instruct>: Given the context 'A detailed analysis of the repression by p21SNFT repression on the IL-2 promoter distal NF-AT/AP-1 site demonstrates that it can bind DNA with NF-AT and Jun, strongly suggesting that it represses NF-AT/AP-1 activity by competing with Fos proteins for Jun dimerization.', select the correct biomedical concept corresponding to 'il-2'. Answer using one of the provided options. | <Options>: A: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
B: il22 (homo sapiens) (aka interleukin 22)
C: interleukin 3 (homo sapiens) (aka interleukin 3)
D: il-2 (homo sapiens) (aka interleukin 2)
E: csf2 (homo sapiens) (aka colony stimulating factor 2)
F: None of the above. | D |
<Instruct>: Given the context 'A detailed analysis of the repression by p21SNFT repression on the IL-2 promoter distal NF-AT/AP-1 site demonstrates that it can bind DNA with NF-AT and Jun, strongly suggesting that it represses NF-AT/AP-1 activity by competing with Fos proteins for Jun dimerization.', select the correct biomedical concept corresponding to 'jun'. Answer using one of the provided options. | <Options>: A: juno (homo sapiens) (aka izumo1 receptor, juno)
B: junb proto-oncogene, ap-1 transcription factor subunit (homo sapiens) (aka junb proto-oncogene, ap-1 transcription factor subunit)
C: jund proto-oncogene, ap-1 transcription factor subunit (homo sapiens) (aka jund proto-oncogene, ap-1 transcription factor subunit)
D: jun (mus musculus) (aka jun proto-oncogene)
E: jun (homo sapiens) (aka jun proto-oncogene, ap-1 transcription factor subunit)
F: None of the above. | E |
<Instruct>: Given the context 'A detailed analysis of the repression by p21SNFT repression on the IL-2 promoter distal NF-AT/AP-1 site demonstrates that it can bind DNA with NF-AT and Jun, strongly suggesting that it represses NF-AT/AP-1 activity by competing with Fos proteins for Jun dimerization.', select the correct biomedical concept corresponding to 'fos'. Answer using one of the provided options. | <Options>: A: fos (mus musculus) (aka fbj osteosarcoma oncogene)
B: fos like 2, ap-1 transcription factor subunit (homo sapiens) (aka fos like 2, ap-1 transcription factor subunit)
C: fosb proto-oncogene, ap-1 transcription factor subunit (homo sapiens) (aka fosb proto-oncogene, ap-1 transcription factor subunit)
D: fos (homo sapiens) (aka fos proto-oncogene, ap-1 transcription factor subunit)
E: c-fos (xenopus laevis) (fbj murine osteosarcoma viral oncogene homolog s homeolog (xenopus laevis)) (aka fbj murine osteosarcoma viral oncogene homolog s homeolog)
F: None of the above. | D |
<Instruct>: Given the context 'A detailed analysis of the repression by p21SNFT repression on the IL-2 promoter distal NF-AT/AP-1 site demonstrates that it can bind DNA with NF-AT and Jun, strongly suggesting that it represses NF-AT/AP-1 activity by competing with Fos proteins for Jun dimerization.', select the correct biomedical concept corresponding to 'jun'. Answer using one of the provided options. | <Options>: A: jun proto-oncogene, ap-1 transcription factor subunit (homo sapiens) (aka jun proto-oncogene, ap-1 transcription factor subunit)
B: juno (homo sapiens) (aka izumo1 receptor, juno)
C: jun (mus musculus) (aka jun proto-oncogene)
D: jund (homo sapiens) (aka jund proto-oncogene, ap-1 transcription factor subunit)
E: junb proto-oncogene, ap-1 transcription factor subunit (homo sapiens) (aka junb proto-oncogene, ap-1 transcription factor subunit)
F: None of the above. | A |
<Instruct>: Given the context 'A detailed analysis of the repression by p21SNFT repression on the IL-2 promoter distal NF-AT/AP-1 site demonstrates that it can bind DNA with NF-AT and Jun, strongly suggesting that it represses NF-AT/AP-1 activity by competing with Fos proteins for Jun dimerization.', select the correct biomedical concept corresponding to 'jun'. Answer using one of the provided options. | <Options>: A: jun (mus musculus) (aka jun proto-oncogene)
B: juno (homo sapiens) (aka izumo1 receptor, juno)
C: jund (homo sapiens) (aka jund proto-oncogene, ap-1 transcription factor subunit)
D: junb proto-oncogene, ap-1 transcription factor subunit (homo sapiens) (aka junb proto-oncogene, ap-1 transcription factor subunit)
E: None of the above. | E |
<Instruct>: Given the context 'The importance of this repression is that p21SNFT inhibits the trans-activation potential of protein complexes that contain Jun, thereby demonstrating an additional level of control for the highly regulated, ubiquitous AP-1 transcription factor and the IL-2 gene.', select the correct biomedical concept corresponding to 'p21snft'. Answer using one of the provided options. | <Options>: A: nst1 (saccharomyces cerevisiae s288c) (aka nst1p)
B: cstf2t (homo sapiens) (aka cleavage stimulation factor subunit 2 tau variant)
C: rft1 homolog (rattus norvegicus) (aka rft1 homolog)
D: snft (homo sapiens) (aka basic leucine zipper atf-like transcription factor 3)
E: nft1 (saccharomyces cerevisiae s288c) (uncharacterized protein (saccharomyces cerevisiae s288c)) (aka uncharacterized protein)
F: None of the above. | D |
<Instruct>: Given the context 'The importance of this repression is that p21SNFT inhibits the trans-activation potential of protein complexes that contain Jun, thereby demonstrating an additional level of control for the highly regulated, ubiquitous AP-1 transcription factor and the IL-2 gene.', select the correct biomedical concept corresponding to 'jun'. Answer using one of the provided options. | <Options>: A: ap-1 (homo sapiens) (jun proto-oncogene, ap-1 transcription factor subunit (homo sapiens)) (aka jun proto-oncogene, ap-1 transcription factor subunit)
B: jun (mus musculus) (aka jun proto-oncogene)
C: junb proto-oncogene, ap-1 transcription factor subunit (homo sapiens) (aka junb proto-oncogene, ap-1 transcription factor subunit)
D: juno (homo sapiens) (aka izumo1 receptor, juno)
E: jund (homo sapiens) (aka jund proto-oncogene, ap-1 transcription factor subunit)
F: None of the above. | A |
<Instruct>: Given the context 'The importance of this repression is that p21SNFT inhibits the trans-activation potential of protein complexes that contain Jun, thereby demonstrating an additional level of control for the highly regulated, ubiquitous AP-1 transcription factor and the IL-2 gene.', select the correct biomedical concept corresponding to 'il-2'. Answer using one of the provided options. | <Options>: A: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
B: interleukin 3 (homo sapiens) (aka interleukin 3)
C: csf2 (homo sapiens) (aka colony stimulating factor 2)
D: il2 (homo sapiens) (aka interleukin 2)
E: il22 (homo sapiens) (aka interleukin 22)
F: None of the above. | D |
<Instruct>: Given the context 'Identification of distinct surface-expressed and intracellular CXC-chemokine receptor 2 glycoforms in neutrophils: N-glycosylation is essential for maintenance of receptor surface expression.
', select the correct biomedical concept corresponding to 'cxc-chemokine receptor 2'. Answer using one of the provided options. | <Options>: A: chemokine (c-c motif) receptor 2 (xenopus tropicalis) (aka chemokine (c-c motif) receptor 2)
B: c-x-c motif chemokine receptor 1 (homo sapiens) (aka c-x-c motif chemokine receptor 1)
C: cmkbr2 (homo sapiens) (aka c-c motif chemokine receptor 2)
D: atypical chemokine receptor 2 (homo sapiens) (aka atypical chemokine receptor 2)
E: il8r2 (homo sapiens) (aka c-x-c motif chemokine receptor 2)
F: None of the above. | E |
<Instruct>: Given the context 'The G protein-coupled CXC-chemokine receptor CXCR-2 mediates activation of neutrophil effector functions in response to multiple ligands, including IL-8 and neutrophil-activating peptide 2 (NAP-2).', select the correct biomedical concept corresponding to 'cxcr-2'. Answer using one of the provided options. | <Options>: A: cmkbr2 (homo sapiens) (aka c-c motif chemokine receptor 2)
B: c-x-c motif chemokine receptor 2 (homo sapiens) (aka c-x-c motif chemokine receptor 2)
C: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
D: None of the above. | B |
<Instruct>: Given the context 'The G protein-coupled CXC-chemokine receptor CXCR-2 mediates activation of neutrophil effector functions in response to multiple ligands, including IL-8 and neutrophil-activating peptide 2 (NAP-2).', select the correct biomedical concept corresponding to 'il-8'. Answer using one of the provided options. | <Options>: A: il1f8 (homo sapiens) (aka interleukin 36 beta)
B: cxcl8 (homo sapiens) (aka c-x-c motif chemokine ligand 8)
C: ck-8 (homo sapiens) (aka keratin 8)
D: scya8 (homo sapiens) (aka c-c motif chemokine ligand 8)
E: fgf-8 (homo sapiens) (aka fibroblast growth factor 8)
F: None of the above. | B |
<Instruct>: Given the context 'The G protein-coupled CXC-chemokine receptor CXCR-2 mediates activation of neutrophil effector functions in response to multiple ligands, including IL-8 and neutrophil-activating peptide 2 (NAP-2).', select the correct biomedical concept corresponding to 'neutrophil-activating peptide 2'. Answer using one of the provided options. | <Options>: A: mip-2g (homo sapiens) (aka c-x-c motif chemokine ligand 14)
B: nap-2 (homo sapiens) (aka pro-platelet basic protein)
C: mip-2b (homo sapiens) (aka c-x-c motif chemokine ligand 3)
D: leukocyte cell derived chemotaxin 2 (homo sapiens) (aka leukocyte cell derived chemotaxin 2)
E: neutrophil cytosolic factor 2 (homo sapiens) (aka neutrophil cytosolic factor 2)
F: None of the above. | B |
<Instruct>: Given the context 'The G protein-coupled CXC-chemokine receptor CXCR-2 mediates activation of neutrophil effector functions in response to multiple ligands, including IL-8 and neutrophil-activating peptide 2 (NAP-2).', select the correct biomedical concept corresponding to 'nap-2'. Answer using one of the provided options. | <Options>: A: ngfi-a binding protein 2 (homo sapiens) (aka ngfi-a binding protein 2)
B: nap2l (homo sapiens) (aka nucleosome assembly protein 1 like 4)
C: nac-2 (homo sapiens) (aka nacc family member 2)
D: nap-2 (homo sapiens) (aka pro-platelet basic protein)
E: napp2 (homo sapiens) (aka peroxisomal biogenesis factor 14)
F: None of the above. | D |
<Instruct>: Given the context 'Although CXCR-2 has been successfully cloned and expressed in several cell lines, the molecular properties of the native neutrophil-expressed receptor have remained largely undefined.', select the correct biomedical concept corresponding to 'cxcr-2'. Answer using one of the provided options. | <Options>: A: il8r2 (homo sapiens) (aka c-x-c motif chemokine receptor 2)
B: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
C: cc-ckr-2 (homo sapiens) (aka c-c motif chemokine receptor 2)
D: None of the above. | A |
<Instruct>: Given the context 'Here we report on the identification and characterization of distinct CXCR-2 glycoforms and their subcellular distribution in neutrophils.', select the correct biomedical concept corresponding to 'cxcr-2'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
B: c-c motif chemokine receptor 2 (homo sapiens) (aka c-c motif chemokine receptor 2)
C: c-x-c motif chemokine receptor 2 (homo sapiens) (aka c-x-c motif chemokine receptor 2)
D: None of the above. | C |
<Instruct>: Given the context 'Here we report on the identification and characterization of distinct CXCR-2 glycoforms and their subcellular distribution in neutrophils.', select the correct biomedical concept corresponding to 'cxcr-2'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
B: ckr2 (homo sapiens) (aka c-c motif chemokine receptor 2)
C: None of the above. | C |
<Instruct>: Given the context 'Immunoprecipitation and Western blot analyses of surface-expressed receptors covalently linked to IL-8 or NAP-2 as well as in their unloaded state revealed the occurrence of a single CXCR-2 variant with an apparent size of 56 kDa.', select the correct biomedical concept corresponding to 'il-8'. Answer using one of the provided options. | <Options>: A: c-x-c motif chemokine ligand 8 (homo sapiens) (aka c-x-c motif chemokine ligand 8)
B: scya8 (homo sapiens) (aka c-c motif chemokine ligand 8)
C: il18 (homo sapiens) (aka interleukin 18)
D: fgf-8 (homo sapiens) (aka fibroblast growth factor 8)
E: ck-8 (homo sapiens) (aka keratin 8)
F: None of the above. | A |
<Instruct>: Given the context 'Immunoprecipitation and Western blot analyses of surface-expressed receptors covalently linked to IL-8 or NAP-2 as well as in their unloaded state revealed the occurrence of a single CXCR-2 variant with an apparent size of 56 kDa.', select the correct biomedical concept corresponding to 'nap-2'. Answer using one of the provided options. | <Options>: A: nap-2 (homo sapiens) (aka pro-platelet basic protein)
B: nac-2 (homo sapiens) (aka nacc family member 2)
C: nap2l (homo sapiens) (aka nucleosome assembly protein 1 like 4)
D: nipsnap homolog 2 (xenopus tropicalis) (aka nipsnap homolog 2)
E: ngfi-a binding protein 2 (homo sapiens) (aka ngfi-a binding protein 2)
F: None of the above. | A |
<Instruct>: Given the context 'Immunoprecipitation and Western blot analyses of surface-expressed receptors covalently linked to IL-8 or NAP-2 as well as in their unloaded state revealed the occurrence of a single CXCR-2 variant with an apparent size of 56 kDa.', select the correct biomedical concept corresponding to 'cxcr-2'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
B: il8rb (homo sapiens) (aka c-x-c motif chemokine receptor 2)
C: cmkbr2 (homo sapiens) (aka c-c motif chemokine receptor 2)
D: None of the above. | B |
<Instruct>: Given the context 'According to deglycosylation experiments surface-expressed CXCR-2 carries two N-linked 9-kDa carbohydrate moieties that are both of complex structure.', select the correct biomedical concept corresponding to 'cxcr-2'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
B: cmkbr2 (homo sapiens) (aka c-c motif chemokine receptor 2)
C: c-x-c motif chemokine receptor 2 (homo sapiens) (aka c-x-c motif chemokine receptor 2)
D: None of the above. | C |
<Instruct>: Given the context 'In addition, two other CXCR-2 variants of 38 and 40 kDa were found to occur exclusively intracellular and to carry N-glycosylations of high mannose or hybrid type.', select the correct biomedical concept corresponding to 'cxcr-2'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
B: il8rb (homo sapiens) (aka c-x-c motif chemokine receptor 2)
C: ckr2 (homo sapiens) (aka c-c motif chemokine receptor 2)
D: None of the above. | B |
<Instruct>: Given the context 'These receptors did not participate in ligand-induced receptor trafficking, while surface-expressed CXCR-2 was internalized and re-expressed following stimulation with NAP-2.', select the correct biomedical concept corresponding to 'cxcr-2'. Answer using one of the provided options. | <Options>: A: il8r2 (homo sapiens) (aka c-x-c motif chemokine receptor 2)
B: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
C: ckr2 (homo sapiens) (aka c-c motif chemokine receptor 2)
D: None of the above. | A |
<Instruct>: Given the context 'These receptors did not participate in ligand-induced receptor trafficking, while surface-expressed CXCR-2 was internalized and re-expressed following stimulation with NAP-2.', select the correct biomedical concept corresponding to 'nap-2'. Answer using one of the provided options. | <Options>: A: nabp2 (homo sapiens) (aka nucleic acid binding protein 2)
B: ngfi-a binding protein 2 (homo sapiens) (aka ngfi-a binding protein 2)
C: nipsnap homolog 2 (xenopus tropicalis) (aka nipsnap homolog 2)
D: nap2l (homo sapiens) (aka nucleosome assembly protein 1 like 4)
E: nap-2 (homo sapiens) (aka pro-platelet basic protein)
F: None of the above. | E |
<Instruct>: Given the context 'By enzymatic removal of one 9-kDa carbohydrate moiety in surface-expressed CXCR-2 we can show that neither NAP-2-induced trafficking nor signaling of the receptor is dependent on its full glycosylation.', select the correct biomedical concept corresponding to 'cxcr-2'. Answer using one of the provided options. | <Options>: A: c-x-c motif chemokine receptor 2 (homo sapiens) (aka c-x-c motif chemokine receptor 2)
B: cmkbr2 (homo sapiens) (aka c-c motif chemokine receptor 2)
C: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
D: None of the above. | A |
<Instruct>: Given the context 'By enzymatic removal of one 9-kDa carbohydrate moiety in surface-expressed CXCR-2 we can show that neither NAP-2-induced trafficking nor signaling of the receptor is dependent on its full glycosylation.', select the correct biomedical concept corresponding to 'nap-2'. Answer using one of the provided options. | <Options>: A: nipsnap homolog 2 (homo sapiens) (aka nipsnap homolog 2)
B: nap2l (homo sapiens) (aka nucleosome assembly protein 1 like 4)
C: ngfi-a binding protein 2 (homo sapiens) (aka ngfi-a binding protein 2)
D: nap-2 (homo sapiens) (aka pro-platelet basic protein)
E: napp2 (homo sapiens) (aka peroxisomal biogenesis factor 14)
F: None of the above. | D |
<Instruct>: Given the context 'Instead, glycosylation was found to protect CXCR-2 from proteolytic attack, as even partial deglycosylation is associated with serine protease-mediated disappearance of the receptor from the neutrophil surface.', select the correct biomedical concept corresponding to 'cxcr-2'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
B: cxcr2 (homo sapiens) (aka c-x-c motif chemokine receptor 2)
C: c-c motif chemokine receptor 2 (homo sapiens) (aka c-c motif chemokine receptor 2)
D: None of the above. | B |
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