instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'The discovery of this new RX response element provides a means for distinguishing between the two retinoid receptor systems and suggests that an RXR-mediated pathway exists for modulating vitamin A metabolism.', select the correct biomedical concept corresponding to 'rxr'. Answer using one of the provided options. | <Options>: A: rxrbeta (homo sapiens) (aka retinoid x receptor beta)
B: rxr-alpha (homo sapiens) (aka retinoid x receptor alpha)
C: rxrc (homo sapiens) (aka retinoid x receptor gamma)
D: nr1h2 (homo sapiens) (aka nuclear receptor subfamily 1 group h member 2)
E: nr1b2 (homo sapiens) (aka retinoic acid receptor beta)
F: None of the above. | B |
<Instruct>: Given the context 'We have isolated a mouse cDNA of 5.7 kb, encoding a new member of the family of receptor-like protein tyrosine phosphatases, termed mRPTP mu.', select the correct biomedical concept corresponding to 'mrptp mu'. Answer using one of the provided options. | <Options>: A: r-ptp-u (mus musculus) (aka protein tyrosine phosphatase receptor type u)
B: lmptp (mus musculus) (aka acid phosphatase 1, soluble)
C: p-ptp-mu (xenopus tropicalis) (aka protein tyrosine phosphatase, receptor type m)
D: r-ptp-mu (homo sapiens) (aka protein tyrosine phosphatase receptor type m)
E: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
F: None of the above. | E |
<Instruct>: Given the context 'In addition, we have cloned the human homologue, hRPTP mu, which shows 98.7% amino acid identity to mRPTP mu.', select the correct biomedical concept corresponding to 'hrptp mu'. Answer using one of the provided options. | <Options>: A: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
B: rptprho (mus musculus) (aka protein tyrosine phosphatase receptor type t)
C: r-ptp-mu (homo sapiens) (aka protein tyrosine phosphatase receptor type m)
D: r-ptp-h (mus musculus) (aka protein tyrosine phosphatase receptor type h)
E: hprt (mus musculus) (aka hypoxanthine phosphoribosyltransferase 1)
F: None of the above. | C |
<Instruct>: Given the context 'In addition, we have cloned the human homologue, hRPTP mu, which shows 98.7% amino acid identity to mRPTP mu.', select the correct biomedical concept corresponding to 'mrptp mu'. Answer using one of the provided options. | <Options>: A: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
B: r-ptp-u (mus musculus) (aka protein tyrosine phosphatase receptor type u)
C: mtrpol (mus musculus) (aka polymerase (rna) mitochondrial (dna directed))
D: p-ptp-mu (xenopus tropicalis) (aka protein tyrosine phosphatase, receptor type m)
E: mtppt1 (mus musculus) (aka solute carrier family 44, member 4)
F: None of the above. | A |
<Instruct>: Given the context 'In addition, we have cloned the human homologue, hRPTP mu, which shows 98.7% amino acid identity to mRPTP mu.', select the correct biomedical concept corresponding to 'mrptp mu'. Answer using one of the provided options. | <Options>: A: p-ptp-mu (xenopus tropicalis) (aka protein tyrosine phosphatase, receptor type m)
B: mrptprho (mus musculus) (aka protein tyrosine phosphatase receptor type t)
C: lmptp (mus musculus) (aka acid phosphatase 1, soluble)
D: mtppt1 (mus musculus) (aka solute carrier family 44, member 4)
E: r-ptp-mu (homo sapiens) (aka protein tyrosine phosphatase receptor type m)
F: None of the above. | F |
<Instruct>: Given the context 'The predicted mRPTP mu protein consists of a 722 amino acid extracellular region, containing 13 potential N-glycosylation sites, a single transmembrane domain and a 688 amino acid intracellular part containing 2 tandem repeats homologous to the catalytic domains of other tyrosine phosphatases.', select the correct biomedical concept corresponding to 'mrptp mu'. Answer using one of the provided options. | <Options>: A: mrptprho (mus musculus) (aka protein tyrosine phosphatase receptor type t)
B: lmptp (mus musculus) (aka acid phosphatase 1, soluble)
C: mtrpol (mus musculus) (aka polymerase (rna) mitochondrial (dna directed))
D: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
E: mtppt1 (mus musculus) (aka solute carrier family 44, member 4)
F: None of the above. | D |
<Instruct>: Given the context 'Transfection of the mRPTP mu cDNA into COS cells results in the synthesis of a protein with an apparent Mr of 195,000, as detected in immunoblots using an antipeptide antibody.', select the correct biomedical concept corresponding to 'mrptp mu'. Answer using one of the provided options. | <Options>: A: lmptp (mus musculus) (aka acid phosphatase 1, soluble)
B: rptpmu (mus musculus) (aka protein tyrosine phosphatase receptor type m)
C: mtppt1 (mus musculus) (aka solute carrier family 44, member 4)
D: r-ptp-mu (homo sapiens) (aka protein tyrosine phosphatase receptor type m)
E: p-ptp-mu (xenopus tropicalis) (aka protein tyrosine phosphatase, receptor type m)
F: None of the above. | B |
<Instruct>: Given the context 'The human RPTP mu gene is localized on chromosome 18pter-q11, a region with frequent abnormalities implicated in human cancer.', select the correct biomedical concept corresponding to 'rptp mu'. Answer using one of the provided options. | <Options>: A: protein tyrosine phosphatase receptor type u (homo sapiens) (aka protein tyrosine phosphatase receptor type u)
B: p-ptp-mu (xenopus tropicalis) (aka protein tyrosine phosphatase, receptor type m)
C: rptpalpha (mus musculus) (aka protein tyrosine phosphatase receptor type a)
D: ptp (mus musculus) (protein tyrosine phosphatase receptor type u (mus musculus)) (aka protein tyrosine phosphatase receptor type u)
E: r-ptp-mu (homo sapiens) (aka protein tyrosine phosphatase receptor type m)
F: None of the above. | E |
<Instruct>: Given the context 'Cytotoxic lymphocyte maturation factor (CLMF) is a disulfide-bonded heterodimeric lymphokine that (i) acts as a growth factor for activated T cells independent of interleukin 2 and (ii) synergizes with suboptimal concentrations of interleukin 2 to induce lymphokine-activated killer cells.', select the correct biomedical concept corresponding to 'interleukin 2'. Answer using one of the provided options. | <Options>: A: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
B: interleukin 7 (homo sapiens) (aka interleukin 7)
C: il-2 (homo sapiens) (aka interleukin 2)
D: interleukin 3 (homo sapiens) (aka interleukin 3)
E: ilf2 (homo sapiens) (aka interleukin enhancer binding factor 2)
F: None of the above. | C |
<Instruct>: Given the context 'Cytotoxic lymphocyte maturation factor (CLMF) is a disulfide-bonded heterodimeric lymphokine that (i) acts as a growth factor for activated T cells independent of interleukin 2 and (ii) synergizes with suboptimal concentrations of interleukin 2 to induce lymphokine-activated killer cells.', select the correct biomedical concept corresponding to 'interleukin 2'. Answer using one of the provided options. | <Options>: A: ilf2 (homo sapiens) (aka interleukin enhancer binding factor 2)
B: interleukin 7 (homo sapiens) (aka interleukin 7)
C: il2 (homo sapiens) (aka interleukin 2)
D: colony stimulating factor 2 (homo sapiens) (aka colony stimulating factor 2)
E: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
F: None of the above. | C |
<Instruct>: Given the context 'Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
B: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
C: bcm1 (homo sapiens) (aka cd48 molecule)
D: bcrm1 (homo sapiens) (aka sideroflexin 4)
E: bcm-1 (mus musculus) (aka cd48 antigen)
F: None of the above. | E |
<Instruct>: Given the context 'Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen.', select the correct biomedical concept corresponding to 'ox45'. Answer using one of the provided options. | <Options>: A: gpr45 (oryctolagus cuniculus) (aka g protein-coupled receptor 45)
B: of45 (rattus norvegicus) (aka matrix extracellular phosphoglycoprotein)
C: g protein-coupled receptor 45 (rattus norvegicus) (aka g protein-coupled receptor 45)
D: olfactory receptor family 4 subfamily c member 45 (gene/pseudogene) (homo sapiens) (aka olfactory receptor family 4 subfamily c member 45 (gene/pseudogene))
E: vacuolar protein sorting 45 homolog (oryctolagus cuniculus) (aka vacuolar protein sorting 45 homolog)
F: None of the above. | F |
<Instruct>: Given the context 'Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen.', select the correct biomedical concept corresponding to 'blast-1'. Answer using one of the provided options. | <Options>: A: hcpeb-1 (homo sapiens) (aka cytoplasmic polyadenylation element binding protein 1)
B: blast (homo sapiens) (aka cd48 molecule)
C: kit ligand (homo sapiens) (aka kit ligand)
D: bm-001 (homo sapiens) (aka cyclin l1)
E: blast1 (mus musculus) (aka cd48 antigen)
F: None of the above. | E |
<Instruct>: Given the context 'Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.
', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
B: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
C: bcrm1 (homo sapiens) (aka sideroflexin 4)
D: bcm1 (homo sapiens) (aka cd48 molecule)
E: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
F: None of the above. | D |
<Instruct>: Given the context 'Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.
', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd22 (homo sapiens) (aka cd22 molecule)
B: cd2 (bos taurus) (aka cd2 molecule)
C: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
D: cd228 (homo sapiens) (aka melanotransferrin)
E: cd2 molecule (homo sapiens) (aka cd2 molecule)
F: None of the above. | E |
<Instruct>: Given the context 'Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.
', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 (bos taurus) (aka cd2 molecule)
B: cd2 (gallus gallus) (aka cd2 molecule)
C: cd21 (homo sapiens) (aka complement c3d receptor 2)
D: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
E: cd22 (homo sapiens) (aka cd22 molecule)
F: None of the above. | F |
<Instruct>: Given the context 'Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.
', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: cd11a (homo sapiens) (aka integrin subunit alpha l)
B: integrin subunit alpha 3 (homo sapiens) (aka integrin subunit alpha 3)
C: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
D: lfa3 (homo sapiens) (aka cd58 molecule)
E: leu-3 (homo sapiens) (aka cd4 molecule)
F: None of the above. | D |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm1 (homo sapiens) (aka cd48 molecule)
B: bcm-1 (mus musculus) (aka cd48 antigen)
C: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
D: bcrm1 (homo sapiens) (aka sideroflexin 4)
E: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
F: None of the above. | B |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'ox45'. Answer using one of the provided options. | <Options>: A: gpr45 (rattus norvegicus) (aka g protein-coupled receptor 45)
B: olfactory receptor family 4 subfamily c member 45 (gene/pseudogene) (homo sapiens) (aka olfactory receptor family 4 subfamily c member 45 (gene/pseudogene))
C: vacuolar protein sorting 45 homolog (oryctolagus cuniculus) (aka vacuolar protein sorting 45 homolog)
D: of45 (rattus norvegicus) (aka matrix extracellular phosphoglycoprotein)
E: olr45 (rattus norvegicus) (aka olfactory receptor family 52 subfamily k member 2)
F: None of the above. | F |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'blast-1'. Answer using one of the provided options. | <Options>: A: bm-001 (homo sapiens) (aka cyclin l1)
B: kit ligand (homo sapiens) (aka kit ligand)
C: bsf-1 (homo sapiens) (aka interleukin 4)
D: blast-1 (mus musculus) (aka cd48 antigen)
E: blast1 (homo sapiens) (aka cd48 molecule)
F: None of the above. | E |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcrm1 (homo sapiens) (aka sideroflexin 4)
B: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
C: bcm-1 (mus musculus) (aka cd48 antigen)
D: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
E: bcm1 (homo sapiens) (aka cd48 molecule)
F: None of the above. | E |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: lfa-3 (homo sapiens) (aka cd58 molecule)
B: lfa-2 (homo sapiens) (aka cd2 molecule)
C: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
D: cd11a (homo sapiens) (aka integrin subunit alpha l)
E: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
F: None of the above. | A |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 (gallus gallus) (aka cd2 molecule)
B: cd2 molecule (homo sapiens) (aka cd2 molecule)
C: cd2 (bos taurus) (aka cd2 molecule)
D: cd22 (homo sapiens) (aka cd22 molecule)
E: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
F: None of the above. | B |
<Instruct>: Given the context 'Mouse BCM1 is widely expressed on leukocytes and is likely to be anchored to the cell surface by a glycosyl-phosphatidylinositol anchor, as is the case for rat and human BCM1 antigen.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm1 (homo sapiens) (aka cd48 molecule)
B: bcm-1 (mus musculus) (aka cd48 antigen)
C: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
D: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
E: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
F: None of the above. | A |
<Instruct>: Given the context 'Mouse BCM1 is widely expressed on leukocytes and is likely to be anchored to the cell surface by a glycosyl-phosphatidylinositol anchor, as is the case for rat and human BCM1 antigen.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm1 (homo sapiens) (aka cd48 molecule)
B: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
C: bcm-1 (mus musculus) (aka cd48 antigen)
D: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
E: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
F: None of the above. | A |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
B: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
C: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
D: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
E: bcm1 (mus musculus) (aka cd48 antigen)
F: None of the above. | E |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
B: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
C: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
D: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
E: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
F: None of the above. | F |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept corresponding to 'bcm-1'. Answer using one of the provided options. | <Options>: A: bcm-1 (mus musculus) (aka cd48 antigen)
B: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
C: mb-1 (homo sapiens) (aka cd79a molecule)
D: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
E: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
F: None of the above. | A |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept corresponding to 'atpa-3'. Answer using one of the provided options. | <Options>: A: atpa-3 (mus musculus) (aka atpase, na+/k+ transporting, alpha 2 polypeptide)
B: atp3 (saccharomyces cerevisiae s288c) (aka f1f0 atp synthase subunit gamma)
C: atp synthase f1 subunit alpha pseudogene 3 (homo sapiens) (aka atp synthase f1 subunit alpha pseudogene 3)
D: atpaf1 (homo sapiens) (aka atp synthase mitochondrial f1 complex assembly factor 1)
E: atp13a3 (homo sapiens) (aka atpase 13a3)
F: None of the above. | A |
<Instruct>: Given the context 'A similar relationship was established between the human BCM1 locus (BCM1) and ATP1A2, and other markers on chromosome 1q.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcrm1 (homo sapiens) (aka sideroflexin 4)
B: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
C: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
D: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
E: bcm1 (homo sapiens) (aka cd48 molecule)
F: None of the above. | E |
<Instruct>: Given the context 'A similar relationship was established between the human BCM1 locus (BCM1) and ATP1A2, and other markers on chromosome 1q.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcrm1 (homo sapiens) (aka sideroflexin 4)
B: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
C: bcm1 (homo sapiens) (aka cd48 molecule)
D: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
E: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
F: None of the above. | C |
<Instruct>: Given the context 'A similar relationship was established between the human BCM1 locus (BCM1) and ATP1A2, and other markers on chromosome 1q.', select the correct biomedical concept corresponding to 'atp1a2'. Answer using one of the provided options. | <Options>: A: atp1a2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 2)
B: atp2a2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
C: atp1a2 (rattus norvegicus) (aka atpase na+/k+ transporting subunit alpha 2)
D: atp1a2 (mus musculus) (aka atpase, na+/k+ transporting, alpha 2 polypeptide)
E: atp6a2 (homo sapiens) (aka atpase h+ transporting v0 subunit a2)
F: None of the above. | A |
<Instruct>: Given the context 'A similar situation is seen in the region of the CD2 and LFA3 genes between mouse chromosome 3 and human chromosome 1p.', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
B: cd21 (homo sapiens) (aka complement c3d receptor 2)
C: cd2 molecule (bos taurus) (aka cd2 molecule)
D: cd2 molecule (homo sapiens) (aka cd2 molecule)
E: cd228 (homo sapiens) (aka melanotransferrin)
F: None of the above. | D |
<Instruct>: Given the context 'A similar situation is seen in the region of the CD2 and LFA3 genes between mouse chromosome 3 and human chromosome 1p.', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
B: cd11a (homo sapiens) (aka integrin subunit alpha l)
C: lfa-2 (homo sapiens) (aka cd2 molecule)
D: lfa3 (homo sapiens) (aka cd58 molecule)
E: leu-3 (homo sapiens) (aka cd4 molecule)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 molecule (bos taurus) (aka cd2 molecule)
B: cd2 (gallus gallus) (aka cd2 molecule)
C: cd2 molecule (homo sapiens) (aka cd2 molecule)
D: cd21 (homo sapiens) (aka complement c3d receptor 2)
E: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
F: None of the above. | C |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: leu-3 (homo sapiens) (aka cd4 molecule)
B: itga3 (homo sapiens) (aka integrin subunit alpha 3)
C: lfa-2 (homo sapiens) (aka cd2 molecule)
D: lfa3 (homo sapiens) (aka cd58 molecule)
E: cd11a (homo sapiens) (aka integrin subunit alpha l)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'atpa-1'. Answer using one of the provided options. | <Options>: A: atp6a (homo sapiens) (aka atpase h+/k+ transporting subunit alpha)
B: atpi (homo sapiens) (aka atp synthase inhibitory factor subunit 1)
C: atp synthase f1 subunit alpha pseudogene 1 (homo sapiens) (aka atp synthase f1 subunit alpha pseudogene 1)
D: atp6n1a (homo sapiens) (aka atpase h+ transporting v0 subunit a1)
E: atp synthase f1 subunit alpha (homo sapiens) (aka atp synthase f1 subunit alpha)
F: None of the above. | F |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'atpa-1'. Answer using one of the provided options. | <Options>: A: atp synthase f1 subunit alpha pseudogene 1 (homo sapiens) (aka atp synthase f1 subunit alpha pseudogene 1)
B: atpiia (homo sapiens) (aka atpase phospholipid transporting 9a (putative))
C: atp6a (homo sapiens) (aka atpase h+/k+ transporting subunit alpha)
D: atpaf1 (homo sapiens) (aka atp synthase mitochondrial f1 complex assembly factor 1)
E: atpia (homo sapiens) (aka atpase phospholipid transporting 8a1)
F: None of the above. | F |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'atp1a1'. Answer using one of the provided options. | <Options>: A: atpase na+/k+ transporting subunit alpha 1 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 1)
B: atp1al1 (homo sapiens) (aka atpase h+/k+ transporting non-gastric alpha2 subunit)
C: atp1a1 (rattus norvegicus) (aka atpase na+/k+ transporting subunit alpha 1)
D: atp1a1os (homo sapiens) (aka atp1a1 antisense rna 1)
E: atp6n1a (homo sapiens) (aka atpase h+ transporting v0 subunit a1)
F: None of the above. | A |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm-1'. Answer using one of the provided options. | <Options>: A: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
B: bcsc-1 (homo sapiens) (aka von willebrand factor a domain containing 5a)
C: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
D: bcm-1 (mus musculus) (aka cd48 antigen)
E: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
B: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
C: bcm1 (homo sapiens) (aka cd48 molecule)
D: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
E: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
F: None of the above. | C |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'atpa-3'. Answer using one of the provided options. | <Options>: A: atp13a3 (homo sapiens) (aka atpase 13a3)
B: atpase na+/k+ transporting subunit alpha 3 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 3)
C: atpa-3 (mus musculus) (aka atpase, na+/k+ transporting, alpha 2 polypeptide)
D: atpap3 (arabidopsis thaliana) (aka purple acid phosphatase 3)
E: atp13a3 (xenopus tropicalis) (aka atpase type 13a3)
F: None of the above. | C |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'atp1a2'. Answer using one of the provided options. | <Options>: A: atp1al2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 4)
B: atp1a2 (mus musculus) (aka atpase, na+/k+ transporting, alpha 2 polypeptide)
C: atpase na+/k+ transporting subunit alpha 2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 2)
D: atp1a2 (rattus norvegicus) (aka atpase na+/k+ transporting subunit alpha 2)
E: atp2a1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1)
F: None of the above. | C |
<Instruct>: Given the context 'Taken together, the data suggest duplication of a chromosome region including the precursors of the genes for BCM1, CD2, and LFA3, and the ATPase genes to give rise to the linkage groups now observed.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
B: bcm1 (homo sapiens) (aka cd48 molecule)
C: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
D: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
E: bcrm1 (homo sapiens) (aka sideroflexin 4)
F: None of the above. | B |
<Instruct>: Given the context 'Taken together, the data suggest duplication of a chromosome region including the precursors of the genes for BCM1, CD2, and LFA3, and the ATPase genes to give rise to the linkage groups now observed.', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 (gallus gallus) (aka cd2 molecule)
B: cd2 molecule (homo sapiens) (aka cd2 molecule)
C: cd22 molecule (homo sapiens) (aka cd22 molecule)
D: cd21 (homo sapiens) (aka complement c3d receptor 2)
E: cd2 (bos taurus) (aka cd2 molecule)
F: None of the above. | B |
<Instruct>: Given the context 'Taken together, the data suggest duplication of a chromosome region including the precursors of the genes for BCM1, CD2, and LFA3, and the ATPase genes to give rise to the linkage groups now observed.', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: lfa-3 (homo sapiens) (aka cd58 molecule)
B: lfa1a (homo sapiens) (aka integrin subunit alpha l)
C: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
D: leu-3 (homo sapiens) (aka cd4 molecule)
E: lfa-2 (homo sapiens) (aka cd2 molecule)
F: None of the above. | A |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 (homo sapiens) (aka cd2 molecule)
B: cd2 (gallus gallus) (aka cd2 molecule)
C: cd22 (homo sapiens) (aka cd22 molecule)
D: cd228 (homo sapiens) (aka melanotransferrin)
E: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
F: None of the above. | A |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
B: lfa-2 (homo sapiens) (aka cd2 molecule)
C: lfa1a (homo sapiens) (aka integrin subunit alpha l)
D: lfa3 (homo sapiens) (aka cd58 molecule)
E: integrin subunit alpha 3 (homo sapiens) (aka integrin subunit alpha 3)
F: None of the above. | D |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
B: itga3 (homo sapiens) (aka integrin subunit alpha 3)
C: leu-3 (homo sapiens) (aka cd4 molecule)
D: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
E: lfa-2 (homo sapiens) (aka cd2 molecule)
F: None of the above. | F |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm-1 (mus musculus) (aka cd48 antigen)
B: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
C: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
D: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
E: bcm1 (homo sapiens) (aka cd48 molecule)
F: None of the above. | E |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: integrin subunit alpha 3 (homo sapiens) (aka integrin subunit alpha 3)
B: lfa-3 (homo sapiens) (aka cd58 molecule)
C: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
D: lfa-2 (homo sapiens) (aka cd2 molecule)
E: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
F: None of the above. | B |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd22 molecule (homo sapiens) (aka cd22 molecule)
B: cd2 molecule (homo sapiens) (aka cd2 molecule)
C: cd2 molecule (bos taurus) (aka cd2 molecule)
D: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
E: cd21 (homo sapiens) (aka complement c3d receptor 2)
F: None of the above. | B |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: lfa1a (homo sapiens) (aka integrin subunit alpha l)
B: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
C: lfa3 (homo sapiens) (aka cd58 molecule)
D: lfa-2 (homo sapiens) (aka cd2 molecule)
E: integrin subunit alpha 3 (homo sapiens) (aka integrin subunit alpha 3)
F: None of the above. | C |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
B: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
C: bcm1 (homo sapiens) (aka cd48 molecule)
D: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
E: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
F: None of the above. | C |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm-1'. Answer using one of the provided options. | <Options>: A: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
B: mbt-1 (homo sapiens) (aka l3mbtl histone methyl-lysine binding protein 3)
C: bcm1 (homo sapiens) (aka cd48 molecule)
D: bcsc-1 (homo sapiens) (aka von willebrand factor a domain containing 5a)
E: bcm-1 (mus musculus) (aka cd48 antigen)
F: None of the above. | E |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
B: bcm1 (homo sapiens) (aka cd48 molecule)
C: bcm-1 (mus musculus) (aka cd48 antigen)
D: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
E: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
F: None of the above. | B |
<Instruct>: Given the context 'The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.
', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnf-r (homo sapiens) (aka tnf receptor superfamily member 1a)
B: tnfr-rp (homo sapiens) (aka lymphotoxin beta receptor)
C: tnfr2 (homo sapiens) (aka tnf receptor superfamily member 1b)
D: None of the above. | A |
<Instruct>: Given the context 'Two proteins which specifically bind tumor necrosis factor (TNF) have recently been isolated from human urine in our laboratory.', select the correct biomedical concept corresponding to 'tumor necrosis factor'. Answer using one of the provided options. | <Options>: A: tnfc (homo sapiens) (aka lymphotoxin beta)
B: tumor necrosis factor (oryctolagus cuniculus) (aka tumor necrosis factor)
C: tnf (homo sapiens) (aka tumor necrosis factor)
D: tumor necrosis factor (xenopus tropicalis) (aka tumor necrosis factor)
E: tnfb (homo sapiens) (aka lymphotoxin alpha)
F: None of the above. | C |
<Instruct>: Given the context 'Two proteins which specifically bind tumor necrosis factor (TNF) have recently been isolated from human urine in our laboratory.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnfc (homo sapiens) (aka lymphotoxin beta)
B: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
C: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
D: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
E: tnfa (homo sapiens) (aka tumor necrosis factor)
F: None of the above. | E |
<Instruct>: Given the context 'Two proteins which specifically bind tumor necrosis factor (TNF) have recently been isolated from human urine in our laboratory.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
B: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
C: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
D: tnfc (homo sapiens) (aka lymphotoxin beta)
E: None of the above. | E |
<Instruct>: Given the context 'Antibodies against one of the two TNF binding proteins (TBPI) were found to have effects characteristic of TNF, including stimulating phosphorylation of specific cellular proteins.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
B: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
C: tnfc (homo sapiens) (aka lymphotoxin beta)
D: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
E: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
F: None of the above. | A |
<Instruct>: Given the context 'Oligonucleotide probes designed on the basis of the NH2-terminal amino acid sequence of TBPI were used to clone the cDNA for the structurally related cell surface type 1 TNF-R. It is notable that although this receptor can signal the phosphorylation of cellular proteins, it appears from its amino acid sequence to be devoid of intrinsic protein kinase activity.', select the correct biomedical concept corresponding to 'cell surface type 1 tnf-r'. Answer using one of the provided options. | <Options>: A: dcr1-tnfr (homo sapiens) (aka tnf receptor superfamily member 10c)
B: tnfr-rp (homo sapiens) (aka lymphotoxin beta receptor)
C: tnfbr (homo sapiens) (aka tnf receptor superfamily member 1b)
D: tnf receptor superfamily member 1a (homo sapiens) (aka tnf receptor superfamily member 1a)
E: None of the above. | D |
<Instruct>: Given the context 'The extracellular domain of the receptor is composed of four internal cysteine-rich repeats, homologous to structures repeated four times in the extracellular domains of the nerve growth factor receptor and the B lymphocytes surface antigen CDw40.', select the correct biomedical concept corresponding to 'nerve growth factor receptor'. Answer using one of the provided options. | <Options>: A: p75tnfr (homo sapiens) (aka tnf receptor superfamily member 1b)
B: ngfr (xenopus tropicalis) (nerve growth factor receptor (xenopus tropicalis)) (aka nerve growth factor receptor)
C: ciliary neurotrophic factor receptor (rattus norvegicus) (aka ciliary neurotrophic factor receptor)
D: ngfr (rattus norvegicus) (aka nerve growth factor receptor)
E: ngfr (homo sapiens) (aka nerve growth factor receptor)
F: None of the above. | E |
<Instruct>: Given the context 'The extracellular domain of the receptor is composed of four internal cysteine-rich repeats, homologous to structures repeated four times in the extracellular domains of the nerve growth factor receptor and the B lymphocytes surface antigen CDw40.', select the correct biomedical concept corresponding to 'cdw40'. Answer using one of the provided options. | <Options>: A: tp40 (homo sapiens) (aka cd7 molecule)
B: interleukin 4 receptor (homo sapiens) (aka interleukin 4 receptor)
C: cd40 molecule (homo sapiens) (aka cd40 molecule)
D: il-40 (homo sapiens) (aka chromosome 17 open reading frame 99)
E: ox40 (homo sapiens) (aka tnf receptor superfamily member 4)
F: None of the above. | C |
<Instruct>: Given the context 'The amino acid composition and size of the extracellular domain of the type I TNF-R closely resemble those of TBPI.', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnfcr (homo sapiens) (aka lymphotoxin beta receptor)
B: tnf-r-ii (homo sapiens) (aka tnf receptor superfamily member 1b)
C: tnf receptor superfamily member 1a (homo sapiens) (aka tnf receptor superfamily member 1a)
D: None of the above. | C |
<Instruct>: Given the context 'The COOH-terminal amino acid sequence of the four cysteine rich repeats within the extracellular domain of the type I TNF-R matches the COOH-terminal sequence of TBPI.', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnfr-rp (homo sapiens) (aka lymphotoxin beta receptor)
B: tnf-r (homo sapiens) (aka tnf receptor superfamily member 1a)
C: tnfr2 (homo sapiens) (aka tnf receptor superfamily member 1b)
D: None of the above. | B |
<Instruct>: Given the context 'On the other hand, amino acid sequences in the soluble form of the type II TNF-R (TBPII), while indicating a marked homology of structure, did not suggest any identity between this protein and the extracellular domain of the type I TNF-R. CHO cells transfected with type I TNF-R cDNA produced both cell surface and soluble forms of the receptor.', select the correct biomedical concept corresponding to 'type ii tnf-r'. Answer using one of the provided options. | <Options>: A: tnfbr (homo sapiens) (aka tnf receptor superfamily member 1b)
B: trail-r2 (homo sapiens) (aka tnf receptor superfamily member 10b)
C: tnfr2-rp (homo sapiens) (aka lymphotoxin beta receptor)
D: tnf-r (homo sapiens) (aka tnf receptor superfamily member 1a)
E: None of the above. | A |
<Instruct>: Given the context 'On the other hand, amino acid sequences in the soluble form of the type II TNF-R (TBPII), while indicating a marked homology of structure, did not suggest any identity between this protein and the extracellular domain of the type I TNF-R. CHO cells transfected with type I TNF-R cDNA produced both cell surface and soluble forms of the receptor.', select the correct biomedical concept corresponding to 'tbpii'. Answer using one of the provided options. | <Options>: A: tbpii (homo sapiens) (aka tnf receptor superfamily member 1b)
B: tbp2 (xenopus laevis) (aka tata-box binding protein like 2 l homeolog)
C: tbpl2 (homo sapiens) (aka tata-box binding protein like 2)
D: tbp-b (xenopus tropicalis) (aka tata-box binding protein)
E: tbp-b (xenopus laevis) (tata-box binding protein s homeolog (xenopus laevis)) (aka tata-box binding protein s homeolog)
F: None of the above. | A |
<Instruct>: Given the context 'On the other hand, amino acid sequences in the soluble form of the type II TNF-R (TBPII), while indicating a marked homology of structure, did not suggest any identity between this protein and the extracellular domain of the type I TNF-R. CHO cells transfected with type I TNF-R cDNA produced both cell surface and soluble forms of the receptor.', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnfr-rp (homo sapiens) (aka lymphotoxin beta receptor)
B: tnf receptor superfamily member 1a (homo sapiens) (aka tnf receptor superfamily member 1a)
C: tnfr2 (homo sapiens) (aka tnf receptor superfamily member 1b)
D: None of the above. | B |
<Instruct>: Given the context 'On the other hand, amino acid sequences in the soluble form of the type II TNF-R (TBPII), while indicating a marked homology of structure, did not suggest any identity between this protein and the extracellular domain of the type I TNF-R. CHO cells transfected with type I TNF-R cDNA produced both cell surface and soluble forms of the receptor.', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnf-r-ii (homo sapiens) (aka tnf receptor superfamily member 1b)
B: tnfr-rp (homo sapiens) (aka lymphotoxin beta receptor)
C: tnfar (homo sapiens) (aka tnf receptor superfamily member 1a)
D: None of the above. | C |
<Instruct>: Given the context 'On the other hand, amino acid sequences in the soluble form of the type II TNF-R (TBPII), while indicating a marked homology of structure, did not suggest any identity between this protein and the extracellular domain of the type I TNF-R. CHO cells transfected with type I TNF-R cDNA produced both cell surface and soluble forms of the receptor.', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnfr2 (homo sapiens) (aka tnf receptor superfamily member 1b)
B: tnfcr (homo sapiens) (aka lymphotoxin beta receptor)
C: None of the above. | C |
<Instruct>: Given the context 'A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
TSG-6 cDNA was isolated by differential screening of a lambda cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
B: tnf alpha induced protein 6 (homo sapiens) (aka tnf alpha induced protein 6)
C: tex6 (homo sapiens) (aka rna polymerase i subunit h)
D: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
E: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
F: None of the above. | B |
<Instruct>: Given the context 'A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
TSG-6 cDNA was isolated by differential screening of a lambda cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts.', select the correct biomedical concept corresponding to 'cd44'. Answer using one of the provided options. | <Options>: A: cd44 molecule (sus scrofa) (aka cd44 molecule)
B: cd44 molecule (in blood group) (oryctolagus cuniculus) (aka cd44 molecule (in blood group))
C: cd44 (homo sapiens) (aka cd44 molecule (in blood group))
D: hyaluronan mediated motility receptor (homo sapiens) (aka hyaluronan mediated motility receptor)
E: cd44 molecule (in blood group) (xenopus tropicalis) (aka cd44 molecule (in blood group))
F: None of the above. | C |
<Instruct>: Given the context 'A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
TSG-6 cDNA was isolated by differential screening of a lambda cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
B: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
C: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
D: tsg-6 (homo sapiens) (aka tnf alpha induced protein 6)
E: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
F: None of the above. | D |
<Instruct>: Given the context 'A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
TSG-6 cDNA was isolated by differential screening of a lambda cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts.', select the correct biomedical concept corresponding to 'tumor necrosis factor'. Answer using one of the provided options. | <Options>: A: tnfc (homo sapiens) (aka lymphotoxin beta)
B: tnfa (homo sapiens) (aka tumor necrosis factor)
C: tnfb (homo sapiens) (aka lymphotoxin alpha)
D: tumor necrosis factor (xenopus tropicalis) (aka tumor necrosis factor)
E: tumor necrosis factor (oryctolagus cuniculus) (aka tumor necrosis factor)
F: None of the above. | B |
<Instruct>: Given the context 'A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
TSG-6 cDNA was isolated by differential screening of a lambda cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
B: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
C: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
D: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
E: tnfb (homo sapiens) (aka lymphotoxin alpha)
F: None of the above. | C |
<Instruct>: Given the context 'We show that TSG-6 mRNA was not detectable in untreated cells, but became readily induced by TNF in normal human fibroblast lines and in peripheral blood mononuclear cells.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tex6 (homo sapiens) (aka rna polymerase i subunit h)
B: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
C: tsg6 (homo sapiens) (aka tnf alpha induced protein 6)
D: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
E: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
F: None of the above. | C |
<Instruct>: Given the context 'We show that TSG-6 mRNA was not detectable in untreated cells, but became readily induced by TNF in normal human fibroblast lines and in peripheral blood mononuclear cells.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
B: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
C: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
D: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
E: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
F: None of the above. | C |
<Instruct>: Given the context 'In contrast, TSG-6 mRNA was undetectable in either control or TNF-treated human vascular endothelial cells and a variety of tumor-derived or virus-transformed cell lines.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
B: tnf alpha induced protein 6 (homo sapiens) (aka tnf alpha induced protein 6)
C: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
D: melanoma-associated transcript 6 (homo sapiens) (aka melanoma-associated transcript 6)
E: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
F: None of the above. | B |
<Instruct>: Given the context 'In contrast, TSG-6 mRNA was undetectable in either control or TNF-treated human vascular endothelial cells and a variety of tumor-derived or virus-transformed cell lines.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
B: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
C: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
D: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
E: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
F: None of the above. | C |
<Instruct>: Given the context 'The sequence of full-length TSG-6 cDNA revealed one major open reading frame predicting a polypeptide of 277 amino acids, including a typical cleavable signal peptide.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
B: tsg6 (homo sapiens) (aka tnf alpha induced protein 6)
C: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
D: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
E: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
F: None of the above. | B |
<Instruct>: Given the context 'The sequence of full-length TSG-6 cDNA revealed one major open reading frame predicting a polypeptide of 277 amino acids, including a typical cleavable signal peptide.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
B: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
C: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
D: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
E: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
F: None of the above. | F |
<Instruct>: Given the context 'The NH2-terminal half of the predicted TSG-6 protein sequence shows a significant homology with a region implicated in hyaluronate binding, present in cartilage link protein, proteoglycan core proteins, and the adhesion receptor CD44.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-6 (homo sapiens) (aka tnf alpha induced protein 6)
B: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
C: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
D: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
E: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
F: None of the above. | A |
<Instruct>: Given the context 'The NH2-terminal half of the predicted TSG-6 protein sequence shows a significant homology with a region implicated in hyaluronate binding, present in cartilage link protein, proteoglycan core proteins, and the adhesion receptor CD44.', select the correct biomedical concept corresponding to 'cartilage link protein'. Answer using one of the provided options. | <Options>: A: protein linkin (caenorhabditis elegans) (aka protein linkin)
B: hyaluronan and proteoglycan link protein 3 (xenopus tropicalis) (aka hyaluronan and proteoglycan link protein 3)
C: link-a (homo sapiens) (aka long intergenic non-protein coding rna 1139)
D: cap-gly domain-containing linker protein 1 homolog (caenorhabditis elegans) (aka cap-gly domain-containing linker protein 1 homolog)
E: hyaluronan and proteoglycan link protein 1 (homo sapiens) (aka hyaluronan and proteoglycan link protein 1)
F: None of the above. | E |
<Instruct>: Given the context 'The NH2-terminal half of the predicted TSG-6 protein sequence shows a significant homology with a region implicated in hyaluronate binding, present in cartilage link protein, proteoglycan core proteins, and the adhesion receptor CD44.', select the correct biomedical concept corresponding to 'cd44'. Answer using one of the provided options. | <Options>: A: cd44 molecule (in blood group) (homo sapiens) (aka cd44 molecule (in blood group))
B: hyaluronan mediated motility receptor (homo sapiens) (aka hyaluronan mediated motility receptor)
C: cd44 molecule (sus scrofa) (aka cd44 molecule)
D: cd44 molecule (in blood group) (oryctolagus cuniculus) (aka cd44 molecule (in blood group))
E: cd44 molecule (in blood group) (xenopus tropicalis) (aka cd44 molecule (in blood group))
F: None of the above. | A |
<Instruct>: Given the context 'The most extensive sequence homology exists between the predicted TSG-6 protein and CD44.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
B: melanoma-associated transcript 6 (homo sapiens) (aka melanoma-associated transcript 6)
C: tex6 (homo sapiens) (aka rna polymerase i subunit h)
D: tsg-6 (homo sapiens) (aka tnf alpha induced protein 6)
E: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
F: None of the above. | D |
<Instruct>: Given the context 'The most extensive sequence homology exists between the predicted TSG-6 protein and CD44.', select the correct biomedical concept corresponding to 'cd44'. Answer using one of the provided options. | <Options>: A: hyaluronan mediated motility receptor (homo sapiens) (aka hyaluronan mediated motility receptor)
B: cd44 molecule (in blood group) (xenopus tropicalis) (aka cd44 molecule (in blood group))
C: cd44 (homo sapiens) (aka cd44 molecule (in blood group))
D: cd44 (mus musculus) (aka cd44 antigen)
E: cd44 molecule (in blood group) (oryctolagus cuniculus) (aka cd44 molecule (in blood group))
F: None of the above. | C |
<Instruct>: Given the context 'Western blot analysis with an antiserum raised against a TSG-6 fusion protein detected a 39-kD glycoprotein in the supernatants of TNF-treated FS-4 cells and of cells transfected with TSG-6 cDNA.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: melanoma-associated transcript 6 (homo sapiens) (aka melanoma-associated transcript 6)
B: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
C: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
D: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
E: tsg-6 (homo sapiens) (aka tnf alpha induced protein 6)
F: None of the above. | E |
<Instruct>: Given the context 'Western blot analysis with an antiserum raised against a TSG-6 fusion protein detected a 39-kD glycoprotein in the supernatants of TNF-treated FS-4 cells and of cells transfected with TSG-6 cDNA.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
B: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
C: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
D: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
E: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
F: None of the above. | E |
<Instruct>: Given the context 'Western blot analysis with an antiserum raised against a TSG-6 fusion protein detected a 39-kD glycoprotein in the supernatants of TNF-treated FS-4 cells and of cells transfected with TSG-6 cDNA.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
B: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
C: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
D: melanoma-associated transcript 6 (homo sapiens) (aka melanoma-associated transcript 6)
E: tsg-6 (homo sapiens) (aka tnf alpha induced protein 6)
F: None of the above. | E |
<Instruct>: Given the context 'Binding of the TSG-6 protein to hyaluronate was demonstrated by coprecipitation.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg6 (homo sapiens) (aka tnf alpha induced protein 6)
B: melanoma-associated transcript 6 (homo sapiens) (aka melanoma-associated transcript 6)
C: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
D: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
E: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
F: None of the above. | A |
<Instruct>: Given the context 'Our data indicate that the inflammatory cytokine (TNF or IL-1)-inducible, secretory TSG-6 protein is a novel member of the family of hyaluronate binding proteins, possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnf (homo sapiens) (aka tumor necrosis factor)
B: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
C: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
D: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
E: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
F: None of the above. | A |
<Instruct>: Given the context 'Our data indicate that the inflammatory cytokine (TNF or IL-1)-inducible, secretory TSG-6 protein is a novel member of the family of hyaluronate binding proteins, possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
B: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
C: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
D: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
E: None of the above. | E |
<Instruct>: Given the context 'Our data indicate that the inflammatory cytokine (TNF or IL-1)-inducible, secretory TSG-6 protein is a novel member of the family of hyaluronate binding proteins, possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.', select the correct biomedical concept corresponding to 'il-1'. Answer using one of the provided options. | <Options>: A: il-1 (homo sapiens) (aka interleukin 1 beta)
B: il-1h1 (homo sapiens) (aka interleukin 36 gamma)
C: il-1h (homo sapiens) (aka interleukin 37)
D: ifn1@ (homo sapiens) (aka interferon, type 1, cluster)
E: ilf-1 (homo sapiens) (aka forkhead box k2)
F: None of the above. | A |
<Instruct>: Given the context 'Our data indicate that the inflammatory cytokine (TNF or IL-1)-inducible, secretory TSG-6 protein is a novel member of the family of hyaluronate binding proteins, possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-6 (homo sapiens) (aka tnf alpha induced protein 6)
B: melanoma-associated transcript 6 (homo sapiens) (aka melanoma-associated transcript 6)
C: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
D: tex6 (homo sapiens) (aka rna polymerase i subunit h)
E: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
F: None of the above. | A |
<Instruct>: Given the context 'Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis.
', select the correct biomedical concept corresponding to 'cdc2'. Answer using one of the provided options. | <Options>: A: cdc2 (homo sapiens) (cyclin dependent kinase 1 (homo sapiens)) (aka cyclin dependent kinase 1)
B: cdc21 (saccharomyces cerevisiae s288c) (aka thymidylate synthase)
C: anaphase promoting complex subunit cdc27 (saccharomyces cerevisiae s288c) (aka anaphase promoting complex subunit cdc27)
D: cdc28 (saccharomyces cerevisiae s288c) (aka cyclin-dependent serine/threonine-protein kinase cdc28)
E: cdc2 (homo sapiens) (dna polymerase delta 1, catalytic subunit (homo sapiens)) (aka dna polymerase delta 1, catalytic subunit)
F: None of the above. | A |
<Instruct>: Given the context 'We now present cloning of a cDNA coding for CHED (cholinesterase-related cell division controller), a human homolog of the Schizosaccharomyces pombe cell division cycle 2 (cdc2)-like kinases, universal controllers of the mitotic cell cycle.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: choline dehydrogenase (homo sapiens) (aka choline dehydrogenase)
B: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
C: ched (xenopus laevis) (aka cyclin-dependent kinase 13 l homeolog)
D: chedda (homo sapiens) (aka atrophin 1)
E: chegdd (homo sapiens) (aka oxidation resistance 1)
F: None of the above. | B |
<Instruct>: Given the context 'We now present cloning of a cDNA coding for CHED (cholinesterase-related cell division controller), a human homolog of the Schizosaccharomyces pombe cell division cycle 2 (cdc2)-like kinases, universal controllers of the mitotic cell cycle.', select the correct biomedical concept corresponding to 'cholinesterase-related cell division controller'. Answer using one of the provided options. | <Options>: A: crescerin-like protein che-12 (caenorhabditis elegans) (aka crescerin-like protein che-12)
B: ches-1-like (drosophila melanogaster) (aka checkpoint suppressor 1-like)
C: hdc homolog, cell cycle regulator (xenopus tropicalis) (aka hdc homolog, cell cycle regulator)
D: ched-related (drosophila melanogaster) (aka uncharacterized protein)
E: copper homeostasis protein cutc homolog (caenorhabditis elegans) (aka copper homeostasis protein cutc homolog)
F: None of the above. | F |
<Instruct>: Given the context 'Library screening, RNA blot hybridization, and direct PCR amplification of cDNA reverse-transcribed from cellular mRNA revealed that CHED mRNA is expressed in multiple tissues, including bone marrow.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: ched (xenopus laevis) (aka cyclin-dependent kinase 13 l homeolog)
B: choline dehydrogenase (homo sapiens) (aka choline dehydrogenase)
C: ched1 (homo sapiens) (aka ovo like zinc finger 2)
D: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
E: chedda (homo sapiens) (aka atrophin 1)
F: None of the above. | D |
<Instruct>: Given the context 'The CHED protein includes the consensus ATP binding and phosphorylation domains characteristic of kinases, displays 34-42% identically aligned amino acid residues with other cdc2-related kinases, and is considerably longer at its amino and carboxyl termini.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: cesd (homo sapiens) (aka lipase a, lysosomal acid type)
B: chrd (gallus gallus) (aka chordin)
C: choline dehydrogenase (homo sapiens) (aka choline dehydrogenase)
D: chegdd (homo sapiens) (aka oxidation resistance 1)
E: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
F: None of the above. | E |
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