instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
|---|---|---|
<Instruct>: Given the context 'Our results provide evidence for two pathways of L1 cleavage, based on ADAM10 localization, that can be activated differentially: 1) direct cleavage at the cell surface, and 2) release and cleavage in secretory vesicles most likely derived from the Golgi apparatus.', select the correct biomedical concept corresponding to 'adam10'. Answer using one of the provided options. | <Options>: A: adam15 (homo sapiens) (aka adam metallopeptidase domain 15)
B: metalloproteinase adam10-like (xenopus tropicalis) (aka metalloproteinase adam10-like)
C: ad10 (homo sapiens) (adam metallopeptidase domain 10 (homo sapiens)) (aka adam metallopeptidase domain 10)
D: adam30 (homo sapiens) (aka adam metallopeptidase domain 30)
E: disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans) (aka disintegrin and metalloproteinase domain-containing protein 10 homolog)
F: None of the above. | C |
<Instruct>: Given the context 'The findings establish a novel role for ADAM10 as a vesicle-based protease.', select the correct biomedical concept corresponding to 'adam10'. Answer using one of the provided options. | <Options>: A: adam30 (homo sapiens) (aka adam metallopeptidase domain 30)
B: adam15 (homo sapiens) (aka adam metallopeptidase domain 15)
C: adam metallopeptidase domain 10 (homo sapiens) (aka adam metallopeptidase domain 10)
D: adam9 (homo sapiens) (aka adam metallopeptidase domain 9)
E: disintegrin and metalloproteinase domain-containing protein 10 homolog (caenorhabditis elegans) (aka disintegrin and metalloproteinase domain-containing protein 10 homolog)
F: None of the above. | C |
<Instruct>: Given the context 'Yaf2 inhibits Myc biological function.
', select the correct biomedical concept corresponding to 'yaf2'. Answer using one of the provided options. | <Options>: A: yaf1 (saccharomyces cerevisiae s288c) (aka oleate-activated transcription factor oaf1)
B: yaf2 (xenopus tropicalis) (aka yy1 associated factor 2)
C: yaf5 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein pex22)
D: yaf1 (homo sapiens) (aka histone deacetylase 2)
E: yaf2 (homo sapiens) (aka yy1 associated factor 2)
F: None of the above. | E |
<Instruct>: Given the context 'Yaf2 inhibits Myc biological function.
', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
B: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
C: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
D: c-myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
E: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
F: None of the above. | D |
<Instruct>: Given the context 'The proto-oncogenes of the myelocytomatosis viral oncogene homolog (MYC) family, including MYC, MYCN and MYCL, encode nuclear proteins that act as transcription factors.', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: mycl proto-oncogene, bhlh transcription factor (homo sapiens) (aka mycl proto-oncogene, bhlh transcription factor)
B: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
C: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
D: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
E: c-myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
F: None of the above. | E |
<Instruct>: Given the context 'The proto-oncogenes of the myelocytomatosis viral oncogene homolog (MYC) family, including MYC, MYCN and MYCL, encode nuclear proteins that act as transcription factors.', select the correct biomedical concept corresponding to 'mycn'. Answer using one of the provided options. | <Options>: A: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog)
B: mycn (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
C: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
D: mycn proto-oncogene, bhlh transcription factor (danio rerio) (aka mycn proto-oncogene, bhlh transcription factor)
E: mycn proto-oncogene, bhlh transcription factor (rattus norvegicus) (aka mycn proto-oncogene, bhlh transcription factor)
F: None of the above. | B |
<Instruct>: Given the context 'The proto-oncogenes of the myelocytomatosis viral oncogene homolog (MYC) family, including MYC, MYCN and MYCL, encode nuclear proteins that act as transcription factors.', select the correct biomedical concept corresponding to 'mycn'. Answer using one of the provided options. | <Options>: A: mycn proto-oncogene, bhlh transcription factor (xenopus tropicalis) (aka mycn proto-oncogene, bhlh transcription factor)
B: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog)
C: mycn, opposite strand (mus musculus) (aka mycn, opposite strand)
D: mycn (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
E: mycn proto-oncogene, bhlh transcription factor (danio rerio) (aka mycn proto-oncogene, bhlh transcription factor)
F: None of the above. | F |
<Instruct>: Given the context 'The proto-oncogenes of the myelocytomatosis viral oncogene homolog (MYC) family, including MYC, MYCN and MYCL, encode nuclear proteins that act as transcription factors.', select the correct biomedical concept corresponding to 'mycl'. Answer using one of the provided options. | <Options>: A: mycl2 (homo sapiens) (aka mycl pseudogene 1)
B: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
C: mycs-like (mus musculus) (aka cdna sequence, aa543401)
D: l-myc (mus musculus) (aka v-myc avian myelocytomatosis viral oncogene lung carcinoma derived)
E: mycl (homo sapiens) (aka mycl proto-oncogene, bhlh transcription factor)
F: None of the above. | E |
<Instruct>: Given the context 'The Myc protein is the best studied member of this family and is involved in cell cycle regulation, differentiation and cell death.', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
B: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
C: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
D: mycl (homo sapiens) (aka mycl proto-oncogene, bhlh transcription factor)
E: myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
F: None of the above. | E |
<Instruct>: Given the context 'We have previously demonstrated that the zinc-finger protein Yaf2 interacts with the central region of MycN and enhances MycN dependent transcriptional activation.', select the correct biomedical concept corresponding to 'yaf2'. Answer using one of the provided options. | <Options>: A: yaf2 (xenopus tropicalis) (aka yy1 associated factor 2)
B: yaf5 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein pex22)
C: yaf2 (bos taurus) (aka yy1 associated factor 2)
D: yaf2 (sus scrofa) (aka yy1 associated factor 2)
E: yaf2 (homo sapiens) (aka yy1 associated factor 2)
F: None of the above. | E |
<Instruct>: Given the context 'We have previously demonstrated that the zinc-finger protein Yaf2 interacts with the central region of MycN and enhances MycN dependent transcriptional activation.', select the correct biomedical concept corresponding to 'mycn'. Answer using one of the provided options. | <Options>: A: mycn proto-oncogene, bhlh transcription factor (rattus norvegicus) (aka mycn proto-oncogene, bhlh transcription factor)
B: mycn (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
C: n-myc (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
D: mycn proto-oncogene, bhlh transcription factor (danio rerio) (aka mycn proto-oncogene, bhlh transcription factor)
E: mycn, opposite strand (mus musculus) (aka mycn, opposite strand)
F: None of the above. | C |
<Instruct>: Given the context 'We have previously demonstrated that the zinc-finger protein Yaf2 interacts with the central region of MycN and enhances MycN dependent transcriptional activation.', select the correct biomedical concept corresponding to 'mycn'. Answer using one of the provided options. | <Options>: A: mycn proto-oncogene, bhlh transcription factor (xenopus tropicalis) (aka mycn proto-oncogene, bhlh transcription factor)
B: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog)
C: mycn (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
D: mycn, opposite strand (mus musculus) (aka mycn, opposite strand)
E: mycn (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
F: None of the above. | C |
<Instruct>: Given the context 'Here we show that Yaf2 also binds to the Myc protein in vivo and in vitro.', select the correct biomedical concept corresponding to 'yaf2'. Answer using one of the provided options. | <Options>: A: yaf2 (bos taurus) (aka yy1 associated factor 2)
B: yaf5 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein pex22)
C: yaf2 (xenopus tropicalis) (aka yy1 associated factor 2)
D: yaf2 (homo sapiens) (aka yy1 associated factor 2)
E: yaf1 (saccharomyces cerevisiae s288c) (aka oleate-activated transcription factor oaf1)
F: None of the above. | D |
<Instruct>: Given the context 'Here we show that Yaf2 also binds to the Myc protein in vivo and in vitro.', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
B: c-myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
C: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
D: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
E: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
F: None of the above. | B |
<Instruct>: Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', select the correct biomedical concept corresponding to 'mycn'. Answer using one of the provided options. | <Options>: A: mycn proto-oncogene, bhlh transcription factor (homo sapiens) (aka mycn proto-oncogene, bhlh transcription factor)
B: mycn, opposite strand (mus musculus) (aka mycn, opposite strand)
C: mycn proto-oncogene, bhlh transcription factor (xenopus tropicalis) (aka mycn proto-oncogene, bhlh transcription factor)
D: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog)
E: mycn proto-oncogene, bhlh transcription factor (danio rerio) (aka mycn proto-oncogene, bhlh transcription factor)
F: None of the above. | A |
<Instruct>: Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', select the correct biomedical concept corresponding to 'yaf2'. Answer using one of the provided options. | <Options>: A: yaf5 (saccharomyces cerevisiae s288c) (aka ubiquitin-protein transferase activating protein pex22)
B: yaf1 (saccharomyces cerevisiae s288c) (aka oleate-activated transcription factor oaf1)
C: yaf2 (xenopus laevis) (aka yy1 associated factor 2 s homeolog)
D: yaf1 (homo sapiens) (aka histone deacetylase 2)
E: yaf2 (homo sapiens) (aka yy1 associated factor 2)
F: None of the above. | E |
<Instruct>: Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
B: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
C: mycl proto-oncogene, bhlh transcription factor (homo sapiens) (aka mycl proto-oncogene, bhlh transcription factor)
D: myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
E: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
F: None of the above. | D |
<Instruct>: Given the context 'In contrast to the activating effect on MycN function, Yaf2 inhibits Myc mediated transactivation and transformation.', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: mycl (homo sapiens) (aka mycl proto-oncogene, bhlh transcription factor)
B: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
C: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
D: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
E: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
F: None of the above. | F |
<Instruct>: Given the context 'This differential influence on two members of the Myc family gives insight into a new mechanism to modulate the biological activities of Myc transcription factors.', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
B: c-myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
C: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
D: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
E: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
F: None of the above. | B |
<Instruct>: Given the context 'This differential influence on two members of the Myc family gives insight into a new mechanism to modulate the biological activities of Myc transcription factors.', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
B: myc proto-oncogene, bhlh transcription factor (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
C: mycl proto-oncogene, bhlh transcription factor (homo sapiens) (aka mycl proto-oncogene, bhlh transcription factor)
D: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
E: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
F: None of the above. | B |
<Instruct>: Given the context 'Bacteria expressing the kinase domain of the keratinocyte growth factor receptor (bek/fibroblast growth factor receptor 2) were infected with a fibroblast cDNA library in a phagemid prokaryotic expression vector and screened with a monoclonal anti-phosphotyrosine antibody.', select the correct biomedical concept corresponding to 'keratinocyte growth factor receptor'. Answer using one of the provided options. | <Options>: A: hbgfr (homo sapiens) (aka fibroblast growth factor receptor 1)
B: fibroblast growth factor receptor 3 (homo sapiens) (aka fibroblast growth factor receptor 3)
C: fgfr2 (homo sapiens) (aka fibroblast growth factor receptor 2)
D: trkb (homo sapiens) (aka neurotrophic receptor tyrosine kinase 2)
E: None of the above. | C |
<Instruct>: Given the context 'Bacteria expressing the kinase domain of the keratinocyte growth factor receptor (bek/fibroblast growth factor receptor 2) were infected with a fibroblast cDNA library in a phagemid prokaryotic expression vector and screened with a monoclonal anti-phosphotyrosine antibody.', select the correct biomedical concept corresponding to 'bek'. Answer using one of the provided options. | <Options>: A: rabepk (bos taurus) (aka rab9 effector protein with kelch motifs)
B: bek (mus musculus) (aka fibroblast growth factor receptor 2)
C: bek (xenopus tropicalis) (aka fibroblast growth factor receptor 2)
D: elk1 (bos taurus) (aka ets transcription factor elk1)
E: bek (homo sapiens) (aka fibroblast growth factor receptor 2)
F: None of the above. | E |
<Instruct>: Given the context 'Bacteria expressing the kinase domain of the keratinocyte growth factor receptor (bek/fibroblast growth factor receptor 2) were infected with a fibroblast cDNA library in a phagemid prokaryotic expression vector and screened with a monoclonal anti-phosphotyrosine antibody.', select the correct biomedical concept corresponding to 'fibroblast growth factor receptor 2'. Answer using one of the provided options. | <Options>: A: fibroblast growth factor receptor 3 (homo sapiens) (aka fibroblast growth factor receptor 3)
B: fibroblast growth factor receptor 2 (homo sapiens) (aka fibroblast growth factor receptor 2)
C: fibroblast growth factor receptor 1 (homo sapiens) (aka fibroblast growth factor receptor 1)
D: fibroblast growth factor receptor 2 (sus scrofa) (aka fibroblast growth factor receptor 2)
E: None of the above. | B |
<Instruct>: Given the context 'Both serine and tyrosine phosphatase activities were completely abolished by mutagenesis of a single cysteine residue conserved in VH1 and the VH1-related (VHR) human protein.', select the correct biomedical concept corresponding to 'vh1-related (vhr) human protein'. Answer using one of the provided options. | <Options>: A: vhrt (homo sapiens) (aka ventricular heart development associated lncrna)
B: hshvrp1 (homo sapiens) (aka transmembrane protein 266)
C: vhnf1 (homo sapiens) (aka hnf1 homeobox b)
D: vhr (homo sapiens) (aka dual specificity phosphatase 3)
E: vho (homo sapiens) (aka growth differentiation factor 11)
F: None of the above. | D |
<Instruct>: Given the context 'These properties suggest that VHR is capable of regulating intracellular events mediated by both tyrosine and serine phosphorylation.', select the correct biomedical concept corresponding to 'vhr'. Answer using one of the provided options. | <Options>: A: vhx (homo sapiens) (aka dual specificity phosphatase 22)
B: vhr (mus musculus) (aka dual specificity phosphatase 3 (vaccinia virus phosphatase vh1-related))
C: vhr (homo sapiens) (aka dual specificity phosphatase 3)
D: ig heavy chain v region 102-like (rattus norvegicus) (aka ig heavy chain v region 102-like)
E: vho (homo sapiens) (aka growth differentiation factor 11)
F: None of the above. | C |
<Instruct>: Given the context 'Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
', select the correct biomedical concept corresponding to 'ah receptor nuclear translocator'. Answer using one of the provided options. | <Options>: A: aryl hydrocarbon receptor nuclear translocator (gallus gallus) (aka aryl hydrocarbon receptor nuclear translocator)
B: aryl hydrocarbon receptor nuclear translocator homolog (caenorhabditis elegans) (aka aryl hydrocarbon receptor nuclear translocator homolog)
C: aryl hydrocarbon receptor nuclear translocator (rattus norvegicus) (aka aryl hydrocarbon receptor nuclear translocator)
D: arnt1 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
E: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
F: None of the above. | D |
<Instruct>: Given the context 'Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
', select the correct biomedical concept corresponding to 'arnt'. Answer using one of the provided options. | <Options>: A: arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens)) (aka aryl hydrocarbon receptor nuclear translocator)
B: arnt2 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator 2)
C: arno (homo sapiens) (aka cytohesin 2)
D: basic helix-loop-helix arnt like 1 (xenopus tropicalis) (aka basic helix-loop-helix arnt like 1)
E: arno3 (homo sapiens) (aka cytohesin 3)
F: None of the above. | A |
<Instruct>: Given the context 'Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
', select the correct biomedical concept corresponding to 'ah receptor'. Answer using one of the provided options. | <Options>: A: aryl hydrocarbon receptor (rattus norvegicus) (aka aryl hydrocarbon receptor)
B: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
C: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
D: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
E: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
F: None of the above. | D |
<Instruct>: Given the context 'Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.
', select the correct biomedical concept corresponding to 'ah receptor'. Answer using one of the provided options. | <Options>: A: aryl hydrocarbon receptor repressor (homo sapiens) (aka aryl hydrocarbon receptor repressor)
B: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
C: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
D: aryl hydrocarbon receptor (rattus norvegicus) (aka aryl hydrocarbon receptor)
E: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
F: None of the above. | F |
<Instruct>: Given the context 'The Ah (dioxin) receptor binds a number of widely disseminated environmental pollutants, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and polycyclic aromatic hydrocarbons, and mediates their carcinogenic effects.', select the correct biomedical concept corresponding to 'ah (dioxin) receptor'. Answer using one of the provided options. | <Options>: A: ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens)) (aka aryl hydrocarbon receptor repressor)
B: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
C: aryl hydrocarbon receptor protein 1 (caenorhabditis elegans) (aka aryl hydrocarbon receptor protein 1)
D: aryl hydrocarbon receptor 1a (danio rerio) (aka aryl hydrocarbon receptor 1a)
E: ahrr1 (danio rerio) (aka aryl-hydrocarbon receptor repressor a)
F: None of the above. | B |
<Instruct>: Given the context 'The ligand-bound receptor activates Cyp 1a1 gene transcription through interaction with specific DNA sequences, termed xenobiotic responsive elements (XREs).', select the correct biomedical concept corresponding to 'cyp 1a1'. Answer using one of the provided options. | <Options>: A: cyp17a1 (homo sapiens) (aka cytochrome p450 family 17 subfamily a member 1)
B: cytochrome p450 family 1 subfamily b member 1 (homo sapiens) (aka cytochrome p450 family 1 subfamily b member 1)
C: cytochrome p450 family 1 subfamily a member 1 (homo sapiens) (aka cytochrome p450 family 1 subfamily a member 1)
D: cytochrome p450 family 1 subfamily a member 1 (bos taurus) (aka cytochrome p450 family 1 subfamily a member 1)
E: 1a1 (homo sapiens) (aka solute carrier family 45 member 2)
F: None of the above. | C |
<Instruct>: Given the context 'The Ah receptor nuclear translocator protein (Arnt) is required for Ah receptor function.', select the correct biomedical concept corresponding to 'ah receptor nuclear translocator'. Answer using one of the provided options. | <Options>: A: aryl hydrocarbon receptor nuclear translocator (rattus norvegicus) (aka aryl hydrocarbon receptor nuclear translocator)
B: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
C: aryl hydrocarbon receptor nuclear translocator (xenopus tropicalis) (aka aryl hydrocarbon receptor nuclear translocator)
D: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
E: aryl hydrocarbon receptor nuclear translocator 2 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator 2)
F: None of the above. | D |
<Instruct>: Given the context 'The Ah receptor nuclear translocator protein (Arnt) is required for Ah receptor function.', select the correct biomedical concept corresponding to 'arnt'. Answer using one of the provided options. | <Options>: A: basic helix-loop-helix arnt like 1 (xenopus tropicalis) (aka basic helix-loop-helix arnt like 1)
B: arntl (homo sapiens) (aka basic helix-loop-helix arnt like 1)
C: arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens)) (aka aryl hydrocarbon receptor nuclear translocator)
D: arnt (mus musculus) (aka aryl hydrocarbon receptor nuclear translocator)
E: arnt (drosophila melanogaster) (aka tango)
F: None of the above. | C |
<Instruct>: Given the context 'The Ah receptor nuclear translocator protein (Arnt) is required for Ah receptor function.', select the correct biomedical concept corresponding to 'ah receptor'. Answer using one of the provided options. | <Options>: A: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
B: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
C: aryl hydrocarbon receptor nuclear translocator (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
D: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
E: aryl hydrocarbon receptor (rattus norvegicus) (aka aryl hydrocarbon receptor)
F: None of the above. | A |
<Instruct>: Given the context 'Arnt is now shown to be a structural component of the XRE binding form of the Ah receptor.', select the correct biomedical concept corresponding to 'arnt'. Answer using one of the provided options. | <Options>: A: basic helix-loop-helix arnt like 1 (homo sapiens) (aka basic helix-loop-helix arnt like 1)
B: arnt2 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator 2)
C: arnt1 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
D: arnt (mus musculus) (aka aryl hydrocarbon receptor nuclear translocator)
E: basic helix-loop-helix arnt like 1 (xenopus tropicalis) (aka basic helix-loop-helix arnt like 1)
F: None of the above. | C |
<Instruct>: Given the context 'Arnt is now shown to be a structural component of the XRE binding form of the Ah receptor.', select the correct biomedical concept corresponding to 'ah receptor'. Answer using one of the provided options. | <Options>: A: aryl hydrocarbon receptor (bos taurus) (aka aryl hydrocarbon receptor)
B: aryl hydrocarbon receptor (homo sapiens) (aka aryl hydrocarbon receptor)
C: aryl hydrocarbon receptor (rattus norvegicus) (aka aryl hydrocarbon receptor)
D: ahrr (homo sapiens) (cytochrome p450 family 1 subfamily a member 1 (homo sapiens)) (aka cytochrome p450 family 1 subfamily a member 1)
E: ahrr (homo sapiens) (aryl hydrocarbon receptor repressor (homo sapiens)) (aka aryl hydrocarbon receptor repressor)
F: None of the above. | B |
<Instruct>: Given the context 'Furthermore, Arnt and the ligand-binding subunit of the receptor were extracted as a complex from the nuclei of cells treated with ligand.', select the correct biomedical concept corresponding to 'arnt'. Answer using one of the provided options. | <Options>: A: basic helix-loop-helix arnt like 1 (xenopus tropicalis) (aka basic helix-loop-helix arnt like 1)
B: arnt (mus musculus) (aka aryl hydrocarbon receptor nuclear translocator)
C: arno (homo sapiens) (aka cytohesin 2)
D: arno3 (homo sapiens) (aka cytohesin 3)
E: arnt (homo sapiens) (aryl hydrocarbon receptor nuclear translocator (homo sapiens)) (aka aryl hydrocarbon receptor nuclear translocator)
F: None of the above. | E |
<Instruct>: Given the context 'Arnt contains a basic helix-loop-helix motif, which may be responsible for interacting with both the XRE and the ligand-binding subunit.', select the correct biomedical concept corresponding to 'arnt'. Answer using one of the provided options. | <Options>: A: arntl (homo sapiens) (aka basic helix-loop-helix arnt like 1)
B: arnt1 (homo sapiens) (aka aryl hydrocarbon receptor nuclear translocator)
C: arnt (mus musculus) (aka aryl hydrocarbon receptor nuclear translocator)
D: arno3 (homo sapiens) (aka cytohesin 3)
E: arno (homo sapiens) (aka cytohesin 2)
F: None of the above. | B |
<Instruct>: Given the context 'Characterization of SAF-A, a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements.
', select the correct biomedical concept corresponding to 'saf-a'. Answer using one of the provided options. | <Options>: A: saf1 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit saf1)
B: saf-a2 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u like 2)
C: saf-a (drosophila melanogaster) (aka uncharacterized protein)
D: saf-a (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
E: safa (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
F: None of the above. | E |
<Instruct>: Given the context 'Characterization of SAF-A, a novel nuclear DNA binding protein from HeLa cells with high affinity for nuclear matrix/scaffold attachment DNA elements.
', select the correct biomedical concept corresponding to 'saf-a'. Answer using one of the provided options. | <Options>: A: saf-1 (homo sapiens) (aka myc associated zinc finger protein)
B: saf-a (xenopus tropicalis) (aka heterogeneous nuclear ribonucleoprotein u (scaffold attachment factor a))
C: saf1 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit saf1)
D: saf (homo sapiens) (aka fas antisense rna 1)
E: saf-b (homo sapiens) (aka scaffold attachment factor b)
F: None of the above. | F |
<Instruct>: Given the context 'We identified four proteins in nuclear extracts from HeLa cells which specifically bind to a scaffold attachment region (SAR) element from the human genome.', select the correct biomedical concept corresponding to 'scaffold attachment region'. Answer using one of the provided options. | <Options>: A: steroid receptor associated and regulated protein (sus scrofa) (aka steroid receptor associated and regulated protein)
B: clk4 associating serine/arginine rich protein (bos taurus) (aka clk4 associating serine/arginine rich protein)
C: serine/threonine kinase receptor associated protein (sus scrofa) (aka serine/threonine kinase receptor associated protein)
D: clk4 associating serine/arginine rich protein (sus scrofa) (aka clk4 associating serine/arginine rich protein)
E: scaffold protein involved in dna repair (sus scrofa) (aka scaffold protein involved in dna repair)
F: None of the above. | F |
<Instruct>: Given the context 'We identified four proteins in nuclear extracts from HeLa cells which specifically bind to a scaffold attachment region (SAR) element from the human genome.', select the correct biomedical concept corresponding to 'sar'. Answer using one of the provided options. | <Options>: A: sarp (homo sapiens) (aka ankyrin repeat domain 42)
B: sara1 (homo sapiens) (aka secretion associated ras related gtpase 1a)
C: sar1 (arabidopsis thaliana) (suppressor of auxin resistance1 (arabidopsis thaliana)) (aka suppressor of auxin resistance1)
D: small regulatory polypeptide of amino acid response (sus scrofa) (aka small regulatory polypeptide of amino acid response)
E: sar (mus musculus) (sarcosinemia autosomal recessive (mus musculus)) (aka sarcosinemia autosomal recessive)
F: None of the above. | F |
<Instruct>: Given the context 'Of these four proteins, SAF-A (scaffold attachment factor A), shows the highest affinity for several homologous and heterologous SAR elements from vertebrate cells.', select the correct biomedical concept corresponding to 'saf-a'. Answer using one of the provided options. | <Options>: A: saf-a (drosophila melanogaster) (aka uncharacterized protein)
B: saf-b (homo sapiens) (aka scaffold attachment factor b)
C: saf-a (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
D: saf-a2 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u like 2)
E: saf1 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit saf1)
F: None of the above. | C |
<Instruct>: Given the context 'Of these four proteins, SAF-A (scaffold attachment factor A), shows the highest affinity for several homologous and heterologous SAR elements from vertebrate cells.', select the correct biomedical concept corresponding to 'scaffold attachment factor a'. Answer using one of the provided options. | <Options>: A: nucleosome assembly factor asf1 (saccharomyces cerevisiae s288c) (aka nucleosome assembly factor asf1)
B: uv-stimulated scaffold protein a homolog (caenorhabditis elegans) (aka uv-stimulated scaffold protein a homolog)
C: safa (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
D: scaffold attachment factor b (xenopus tropicalis) (aka scaffold attachment factor b)
E: uv stimulated scaffold protein a (xenopus tropicalis) (aka uv stimulated scaffold protein a)
F: None of the above. | C |
<Instruct>: Given the context 'Of these four proteins, SAF-A (scaffold attachment factor A), shows the highest affinity for several homologous and heterologous SAR elements from vertebrate cells.', select the correct biomedical concept corresponding to 'sar'. Answer using one of the provided options. | <Options>: A: sra (drosophila melanogaster) (sarah (drosophila melanogaster)) (aka sarah)
B: small regulatory polypeptide of amino acid response (sus scrofa) (aka small regulatory polypeptide of amino acid response)
C: sarp (homo sapiens) (aka ankyrin repeat domain 42)
D: sar1 (arabidopsis thaliana) (suppressor of auxin resistance1 (arabidopsis thaliana)) (aka suppressor of auxin resistance1)
E: sarnp (homo sapiens) (aka sap domain containing ribonucleoprotein)
F: None of the above. | F |
<Instruct>: Given the context 'SAF-A is an abundant nuclear protein and a constituent of the nuclear matrix and scaffold.', select the correct biomedical concept corresponding to 'saf-a'. Answer using one of the provided options. | <Options>: A: safa (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
B: scf ubiquitin ligase complex subunit saf1 (saccharomyces cerevisiae s288c) (aka scf ubiquitin ligase complex subunit saf1)
C: saf-1 (homo sapiens) (aka myc associated zinc finger protein)
D: saf-a2 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u like 2)
E: saf (homo sapiens) (aka fas antisense rna 1)
F: None of the above. | A |
<Instruct>: Given the context 'SAF-A binds at multiple sites to the human SAR element; competition studies with synthetic polynucleotides indicate that these sites most probably reside in the multitude of A/T-stretches which are distributed throughout this element.', select the correct biomedical concept corresponding to 'saf-a'. Answer using one of the provided options. | <Options>: A: safa (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u)
B: saf-1 (homo sapiens) (aka myc associated zinc finger protein)
C: saf-b (homo sapiens) (aka scaffold attachment factor b)
D: saf-a2 (homo sapiens) (aka heterogeneous nuclear ribonucleoprotein u like 2)
E: saf (homo sapiens) (aka fas antisense rna 1)
F: None of the above. | A |
<Instruct>: Given the context 'SAF-A binds at multiple sites to the human SAR element; competition studies with synthetic polynucleotides indicate that these sites most probably reside in the multitude of A/T-stretches which are distributed throughout this element.', select the correct biomedical concept corresponding to 'sar'. Answer using one of the provided options. | <Options>: A: sara1 (homo sapiens) (aka secretion associated ras related gtpase 1a)
B: sra (drosophila melanogaster) (sarah (drosophila melanogaster)) (aka sarah)
C: sarp (homo sapiens) (aka ankyrin repeat domain 42)
D: sar (mus musculus) (sarcosinemia autosomal recessive (mus musculus)) (aka sarcosinemia autosomal recessive)
E: saraf (homo sapiens) (aka store-operated calcium entry associated regulatory factor)
F: None of the above. | F |
<Instruct>: Given the context 'Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigen.
', select the correct biomedical concept corresponding to 'udp-glcnac:gal beta 1-3-galnac-r (glcnac to galnac) beta 1-6glcnac transferase'. Answer using one of the provided options. | <Options>: A: galnt3 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 3)
B: galnt1 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 1)
C: galnact (homo sapiens) (aka beta-1,4-n-acetyl-galactosaminyltransferase 1)
D: galnt2 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 2)
E: c2glcnact (homo sapiens) (aka glucosaminyl (n-acetyl) transferase 1)
F: None of the above. | E |
<Instruct>: Given the context 'A cDNA encoding UDP-GlcNAc:Gal beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase (EC 2.4.1.102), which forms critical branches in O-glycans, has been isolated by an expression cloning approach using Chinese hamster ovary (CHO) cells.', select the correct biomedical concept corresponding to 'udp-glcnac:gal beta 1-3galnac-r (glcnac to galnac) beta 1-6glcnac transferase'. Answer using one of the provided options. | <Options>: A: galnact2 (homo sapiens) (aka chondroitin sulfate n-acetylgalactosaminyltransferase 2)
B: c2gnt (homo sapiens) (aka glucosaminyl (n-acetyl) transferase 1)
C: galnact (homo sapiens) (aka beta-1,4-n-acetyl-galactosaminyltransferase 1)
D: galnt1 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 1)
E: galnt2 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 2)
F: None of the above. | B |
<Instruct>: Given the context 'A cDNA encoding UDP-GlcNAc:Gal beta 1-3GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase (EC 2.4.1.102), which forms critical branches in O-glycans, has been isolated by an expression cloning approach using Chinese hamster ovary (CHO) cells.', select the correct biomedical concept corresponding to 'udp-glcnac:gal beta 1-3galnac-r (glcnac to galnac) beta 1-6glcnac transferase'. Answer using one of the provided options. | <Options>: A: galnact (homo sapiens) (aka beta-1,4-n-acetyl-galactosaminyltransferase 1)
B: galnt2 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 2)
C: galnt6 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 6)
D: galnt3 (homo sapiens) (aka polypeptide n-acetylgalactosaminyltransferase 3)
E: galnact2 (homo sapiens) (aka chondroitin sulfate n-acetylgalactosaminyltransferase 2)
F: None of the above. | F |
<Instruct>: Given the context 'Because the antibody used was found to detect most efficiently the oligosaccharide products attached to leukosialin, the CHO cells were also stably transfected with leukosialin cDNA.', select the correct biomedical concept corresponding to 'leukosialin'. Answer using one of the provided options. | <Options>: A: galn (homo sapiens) (aka galanin and gmap prepropeptide)
B: granulysin (homo sapiens) (aka granulysin)
C: sialophorin (sus scrofa) (aka sialophorin)
D: spn (homo sapiens) (sialophorin (homo sapiens)) (aka sialophorin)
E: sialophorin (bos taurus) (aka sialophorin)
F: None of the above. | D |
<Instruct>: Given the context 'Because the antibody used was found to detect most efficiently the oligosaccharide products attached to leukosialin, the CHO cells were also stably transfected with leukosialin cDNA.', select the correct biomedical concept corresponding to 'leukosialin'. Answer using one of the provided options. | <Options>: A: granulysin (homo sapiens) (aka granulysin)
B: spn (xenopus tropicalis) (sialophorin (xenopus tropicalis)) (aka sialophorin)
C: sialin (homo sapiens) (aka solute carrier family 17 member 5)
D: spn (homo sapiens) (sialophorin (homo sapiens)) (aka sialophorin)
E: leukosialin-like (rattus norvegicus) (aka leukosialin-like)
F: None of the above. | D |
<Instruct>: Given the context 'The expression of the presumed catalytic domain as a fusion protein with the IgG binding domain of protein A enabled us to demonstrate unequivocally that the cDNA encodes the core 2 beta-1,6-N-acetylglucosaminyltransferase, the enzyme responsible for the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures.', select the correct biomedical concept corresponding to 'core 2 beta-1,6-n-acetylglucosaminyltransferase'. Answer using one of the provided options. | <Options>: A: core-2/i-branching beta-1,6-n-acetylglucosaminyltransferase family protein (caenorhabditis elegans) (aka core-2/i-branching beta-1,6-n-acetylglucosaminyltransferase family protein)
B: c2gnt (homo sapiens) (aka glucosaminyl (n-acetyl) transferase 1)
C: c2gnt2 (homo sapiens) (aka glucosaminyl (n-acetyl) transferase 3, mucin type)
D: b3gnt1, beta-1,3-n-acetylgucosaminyltransferase 1, homolog;glyco_trans_2-like domain-containing protein (caenorhabditis elegans) (aka b3gnt1, beta-1,3-n-acetylgucosaminyltransferase 1, homolog;glyco_trans_2-like domain-containing protein)
E: c2glcnact (mus musculus) (aka glucosaminyl (n-acetyl) transferase 1, core 2)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro.
TNF is a proinflammatory cytokine that has pleiotropic effects on cells and tissues, mediated in large part by alterations in target tissue gene expression.', select the correct biomedical concept corresponding to 'tumor necrosis factor-alpha'. Answer using one of the provided options. | <Options>: A: tnfb (homo sapiens) (aka lymphotoxin alpha)
B: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
C: tumor necrosis factor (xenopus tropicalis) (aka tumor necrosis factor)
D: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
E: tnfc (homo sapiens) (aka lymphotoxin beta)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro.
TNF is a proinflammatory cytokine that has pleiotropic effects on cells and tissues, mediated in large part by alterations in target tissue gene expression.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
B: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
C: tnfa (homo sapiens) (aka tumor necrosis factor)
D: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
E: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
F: None of the above. | C |
<Instruct>: Given the context 'We have used the technique of differential hybridization to identify several primary response genes induced by TNF in human umbilical vein endothelial (HUVE) cells, a cell type that is profoundly activated by cytokine treatment.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: lymphotoxin alpha (homo sapiens) (aka lymphotoxin alpha)
B: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
C: tnfc (homo sapiens) (aka lymphotoxin beta)
D: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
E: tnf (homo sapiens) (aka tumor necrosis factor)
F: None of the above. | E |
<Instruct>: Given the context 'One of these cDNA, designated B94, detects a rapidly and transiently induced 4-kb transcript in TNF-treated HUVE cells, and this transcript is superinduced in the concomitant presence of cycloheximide.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: cp94 (homo sapiens) (aka beaded filament structural protein 1)
B: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
C: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
D: p94 (homo sapiens) (aka calpain 3)
E: b94 (homo sapiens) (aka tnf alpha induced protein 2)
F: None of the above. | E |
<Instruct>: Given the context 'One of these cDNA, designated B94, detects a rapidly and transiently induced 4-kb transcript in TNF-treated HUVE cells, and this transcript is superinduced in the concomitant presence of cycloheximide.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
B: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
C: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
D: tnfa (homo sapiens) (aka tumor necrosis factor)
E: tnfc (homo sapiens) (aka lymphotoxin beta)
F: None of the above. | D |
<Instruct>: Given the context 'Other proinflammatory stimuli including IL-1 beta and LPS are also able to induce B94 mRNA expression.', select the correct biomedical concept corresponding to 'il-1 beta'. Answer using one of the provided options. | <Options>: A: ifnb1 (homo sapiens) (aka interferon beta 1)
B: interleukin 36 beta (homo sapiens) (aka interleukin 36 beta)
C: il1beta (homo sapiens) (aka interleukin 1 beta)
D: None of the above. | C |
<Instruct>: Given the context 'Other proinflammatory stimuli including IL-1 beta and LPS are also able to induce B94 mRNA expression.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: b94 (homo sapiens) (aka tnf alpha induced protein 2)
B: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
C: gpr94 (homo sapiens) (aka purinergic receptor p2y13)
D: rp94 (homo sapiens) (aka spermatogenesis associated 7)
E: ly94 (homo sapiens) (aka natural cytotoxicity triggering receptor 1)
F: None of the above. | A |
<Instruct>: Given the context 'Other proinflammatory stimuli including IL-1 beta and LPS are also able to induce B94 mRNA expression.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: ly94 (homo sapiens) (aka natural cytotoxicity triggering receptor 1)
B: gpr94 (homo sapiens) (aka purinergic receptor p2y13)
C: rp94 (homo sapiens) (aka spermatogenesis associated 7)
D: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
E: p94 (homo sapiens) (aka calpain 3)
F: None of the above. | F |
<Instruct>: Given the context 'Nuclear run-on experiments demonstrate that TNF induction of B94 transcript occurs primarily at the level of transcriptional activation.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
B: tnfb (homo sapiens) (aka lymphotoxin alpha)
C: tnfc (homo sapiens) (aka lymphotoxin beta)
D: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
E: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
F: None of the above. | A |
<Instruct>: Given the context 'Nuclear run-on experiments demonstrate that TNF induction of B94 transcript occurs primarily at the level of transcriptional activation.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: gpr94 (homo sapiens) (aka purinergic receptor p2y13)
B: cp94 (homo sapiens) (aka beaded filament structural protein 1)
C: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
D: b94 (homo sapiens) (aka tnf alpha induced protein 2)
E: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
F: None of the above. | D |
<Instruct>: Given the context 'Further, B94 is shown to be a single copy gene that is evolutionarily conserved.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: gpr94 (homo sapiens) (aka purinergic receptor p2y13)
B: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
C: cp94 (homo sapiens) (aka beaded filament structural protein 1)
D: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
E: b94 (homo sapiens) (aka tnf alpha induced protein 2)
F: None of the above. | E |
<Instruct>: Given the context 'Developmental regulation occurs most prominently in mouse embryonic liver and kidney, and a second smaller form of B94 transcript is detected in the placenta and testes.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: cp94 (homo sapiens) (aka beaded filament structural protein 1)
B: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
C: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
D: b94 (homo sapiens) (aka tnf alpha induced protein 2)
E: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
F: None of the above. | D |
<Instruct>: Given the context 'B94 and other TNF-responsive transcripts are also induced during capillary tube formation suggesting overlap between genes induced by TNF and those induced during angiogenesis.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
B: b94 (homo sapiens) (aka tnf alpha induced protein 2)
C: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
D: rp94 (homo sapiens) (aka spermatogenesis associated 7)
E: ly94 (homo sapiens) (aka natural cytotoxicity triggering receptor 1)
F: None of the above. | B |
<Instruct>: Given the context 'B94 and other TNF-responsive transcripts are also induced during capillary tube formation suggesting overlap between genes induced by TNF and those induced during angiogenesis.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
B: tnfa (homo sapiens) (aka tumor necrosis factor)
C: tnfb (homo sapiens) (aka lymphotoxin alpha)
D: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
E: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
F: None of the above. | B |
<Instruct>: Given the context 'B94 and other TNF-responsive transcripts are also induced during capillary tube formation suggesting overlap between genes induced by TNF and those induced during angiogenesis.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
B: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
C: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
D: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
E: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
F: None of the above. | E |
<Instruct>: Given the context 'Sequence analysis of the B94 cDNA reveals an open reading frame encoding a 73-kDa polypeptide that has no homology to any known protein.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
B: ly94 (homo sapiens) (aka natural cytotoxicity triggering receptor 1)
C: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
D: p94 (homo sapiens) (aka calpain 3)
E: b94 (homo sapiens) (aka tnf alpha induced protein 2)
F: None of the above. | E |
<Instruct>: Given the context 'Polyclonal antisera directed against the carboxyl-terminal portion of the B94 protein immunoprecipitates a protein of the predicted molecular mass both from COS cells transfected with a B94 expression vector and from TNF-treated HUVE cells.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
B: p94 (homo sapiens) (aka calpain 3)
C: b94 (homo sapiens) (aka tnf alpha induced protein 2)
D: hg94 (homo sapiens) (aka olfactory receptor family 7 subfamily e member 2 pseudogene)
E: rp94 (homo sapiens) (aka spermatogenesis associated 7)
F: None of the above. | C |
<Instruct>: Given the context 'Polyclonal antisera directed against the carboxyl-terminal portion of the B94 protein immunoprecipitates a protein of the predicted molecular mass both from COS cells transfected with a B94 expression vector and from TNF-treated HUVE cells.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: b94 (homo sapiens) (aka tnf alpha induced protein 2)
B: p94 (homo sapiens) (aka calpain 3)
C: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
D: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
E: cp94 (homo sapiens) (aka beaded filament structural protein 1)
F: None of the above. | A |
<Instruct>: Given the context 'Polyclonal antisera directed against the carboxyl-terminal portion of the B94 protein immunoprecipitates a protein of the predicted molecular mass both from COS cells transfected with a B94 expression vector and from TNF-treated HUVE cells.', select the correct biomedical concept corresponding to 'b94'. Answer using one of the provided options. | <Options>: A: ly94 (homo sapiens) (aka natural cytotoxicity triggering receptor 1)
B: natural killer cells antigen cd94 (bos taurus) (aka natural killer cells antigen cd94)
C: b94 (mus musculus) (aka tumor necrosis factor, alpha-induced protein 2)
D: cd294 (homo sapiens) (aka prostaglandin d2 receptor 2)
E: p94 (homo sapiens) (aka calpain 3)
F: None of the above. | F |
<Instruct>: Given the context 'Polyclonal antisera directed against the carboxyl-terminal portion of the B94 protein immunoprecipitates a protein of the predicted molecular mass both from COS cells transfected with a B94 expression vector and from TNF-treated HUVE cells.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
B: tnfc (homo sapiens) (aka lymphotoxin beta)
C: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
D: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
E: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
F: None of the above. | A |
<Instruct>: Given the context 'A approximately 35-kDa polypeptide with a unique NH2-terminal sequence has been isolated from bovine lung and found to be present on the surface of endothelial cells where it mediates the binding of AGEs (receptor for advanced glycosylation end product or RAGE).', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
B: en-rage (bos taurus) (aka s100 calcium binding protein a12)
C: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
D: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
E: rage (gallus gallus) (aka mok protein kinase)
F: None of the above. | D |
<Instruct>: Given the context 'Using an oligonucleotide probe based on the amino-terminal sequence of RAGE, an apparently full-length cDNA of 1.5 kilobases was isolated from a bovine lung cDNA library.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
B: rage (gallus gallus) (aka mok protein kinase)
C: en-rage (bos taurus) (aka s100 calcium binding protein a12)
D: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
E: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
F: None of the above. | E |
<Instruct>: Given the context 'A partial clone encoding the human counterpart of RAGE, isolated from a human lung library, was found to be approximately 90% homologous to the bovine molecule.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
B: rage1 (homo sapiens) (aka mok protein kinase)
C: rage (xenopus laevis) (aka mok protein kinase l homeolog)
D: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
E: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
F: None of the above. | E |
<Instruct>: Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
B: rage1 (homo sapiens) (aka mok protein kinase)
C: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
D: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
E: en-rage (bos taurus) (aka s100 calcium binding protein a12)
F: None of the above. | C |
<Instruct>: Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
B: rage (xenopus laevis) (aka mok protein kinase l homeolog)
C: en-rage (bos taurus) (aka s100 calcium binding protein a12)
D: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
E: rage (gallus gallus) (aka mok protein kinase)
F: None of the above. | D |
<Instruct>: Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', select the correct biomedical concept corresponding to 'muc 18'. Answer using one of the provided options. | <Options>: A: muc18 (homo sapiens) (aka melanoma cell adhesion molecule)
B: muc-15 (homo sapiens) (aka mucin 15, cell surface associated)
C: ceacam18 (homo sapiens) (aka cea cell adhesion molecule 18)
D: mucin-18 (gallus gallus) (aka melanoma cell adhesion molecule)
E: major urinary protein 18 (mus musculus) (aka major urinary protein 18)
F: None of the above. | A |
<Instruct>: Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', select the correct biomedical concept corresponding to 'ncam'. Answer using one of the provided options. | <Options>: A: ceacam1 (homo sapiens) (aka cea cell adhesion molecule 1)
B: ncam-l1 (homo sapiens) (aka l1 cell adhesion molecule)
C: ncam (neural cell adhesion molecule) homolog (caenorhabditis elegans) (aka ncam (neural cell adhesion molecule) homolog)
D: ncam1 (homo sapiens) (aka neural cell adhesion molecule 1)
E: ncam-l1 (mus musculus) (aka l1 cell adhesion molecule)
F: None of the above. | D |
<Instruct>: Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', select the correct biomedical concept corresponding to 'cd20'. Answer using one of the provided options. | <Options>: A: cd20 (rattus norvegicus) (aka membrane spanning 4-domains a1)
B: cd20l5 (homo sapiens) (aka membrane spanning 4-domains a8)
C: cd20 (homo sapiens) (membrane spanning 4-domains a1 (homo sapiens)) (aka membrane spanning 4-domains a1)
D: cd208 (homo sapiens) (aka lysosomal associated membrane protein 3)
E: cd20l (homo sapiens) (aka membrane spanning 4-domains a3)
F: None of the above. | C |
<Instruct>: Given the context 'Expression of the RAGE cDNA in 293 cells allowed them to bind 125I-AGE-albumin in a saturable and dose-dependent manner (Kd approximately 100 nM), blocked by antibody to RAGE.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
B: rage1 (homo sapiens) (aka mok protein kinase)
C: rage (xenopus laevis) (aka mok protein kinase l homeolog)
D: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
E: rage-1 (xenopus tropicalis) (aka mok protein kinase)
F: None of the above. | D |
<Instruct>: Given the context 'Expression of the RAGE cDNA in 293 cells allowed them to bind 125I-AGE-albumin in a saturable and dose-dependent manner (Kd approximately 100 nM), blocked by antibody to RAGE.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
B: rage-1 (xenopus tropicalis) (aka mok protein kinase)
C: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
D: rage (gallus gallus) (aka mok protein kinase)
E: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
F: None of the above. | F |
<Instruct>: Given the context 'Expression of the RAGE cDNA in 293 cells allowed them to bind 125I-AGE-albumin in a saturable and dose-dependent manner (Kd approximately 100 nM), blocked by antibody to RAGE.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage (gallus gallus) (aka mok protein kinase)
B: rage-1 (homo sapiens) (aka mok protein kinase)
C: en-rage (bos taurus) (aka s100 calcium binding protein a12)
D: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
E: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
F: None of the above. | E |
<Instruct>: Given the context 'Western blots of 293 cells transfected with RAGE cDNA probed with anti-RAGE IgG demonstrated expression of immunoreactive protein compared to its absence in mock-transfected cells.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage (gallus gallus) (aka mok protein kinase)
B: en-rage (bos taurus) (aka s100 calcium binding protein a12)
C: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
D: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
E: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
F: None of the above. | E |
<Instruct>: Given the context 'Western blots of 293 cells transfected with RAGE cDNA probed with anti-RAGE IgG demonstrated expression of immunoreactive protein compared to its absence in mock-transfected cells.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
B: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
C: rage-1 (homo sapiens) (aka mok protein kinase)
D: en-rage (bos taurus) (aka s100 calcium binding protein a12)
E: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
F: None of the above. | B |
<Instruct>: Given the context 'These results suggest that RAGE functions as a cell surface receptor for AGEs, which could potentially mediate cellular effects of this class of glycosylated proteins.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
B: rage (xenopus laevis) (aka mok protein kinase l homeolog)
C: rage-1 (xenopus tropicalis) (aka mok protein kinase)
D: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
E: rage1 (homo sapiens) (aka mok protein kinase)
F: None of the above. | A |
<Instruct>: Given the context 'Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein.
', select the correct biomedical concept corresponding to 'cd59'. Answer using one of the provided options. | <Options>: A: cd54 (homo sapiens) (aka intercellular adhesion molecule 1)
B: cd5 molecule (homo sapiens) (aka cd5 molecule)
C: cd59 (homo sapiens) (aka cd59 molecule (cd59 blood group))
D: cd58 (homo sapiens) (aka cd58 molecule)
E: cd55 (homo sapiens) (aka cd55 molecule (cromer blood group))
F: None of the above. | C |
<Instruct>: Given the context 'Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein.
', select the correct biomedical concept corresponding to 'ly-6'. Answer using one of the provided options. | <Options>: A: slam family member 6 (homo sapiens) (aka slam family member 6)
B: ly-6d (homo sapiens) (aka lymphocyte antigen 6 family member d)
C: ly-6k (homo sapiens) (aka lymphocyte antigen 6 family member k)
D: lymphocyte antigen 6 family member s (homo sapiens) (aka lymphocyte antigen 6 family member s)
E: lir-6 (homo sapiens) (aka leukocyte immunoglobulin like receptor a1)
F: None of the above. | F |
<Instruct>: Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', select the correct biomedical concept corresponding to 'cd59'. Answer using one of the provided options. | <Options>: A: cd59 molecule (cd59 blood group) (homo sapiens) (aka cd59 molecule (cd59 blood group))
B: cd52 (homo sapiens) (aka cd52 molecule)
C: cd55 (homo sapiens) (aka cd55 molecule (cromer blood group))
D: cd51 (homo sapiens) (aka integrin subunit alpha v)
E: cd58 (homo sapiens) (aka cd58 molecule)
F: None of the above. | A |
<Instruct>: Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', select the correct biomedical concept corresponding to 'membrane inhibitor of reactive lysis'. Answer using one of the provided options. | <Options>: A: migration and invasion inhibitory protein (bos taurus) (aka migration and invasion inhibitory protein)
B: metalloproteinase inhibitor 1-like (bos taurus) (aka metalloproteinase inhibitor 1-like)
C: ribonuclease/angiogenin inhibitor 1 (mus musculus) (aka ribonuclease/angiogenin inhibitor 1)
D: bmp and activin membrane bound inhibitor (homo sapiens) (aka bmp and activin membrane bound inhibitor)
E: cd59 molecule (cd59 blood group) (homo sapiens) (aka cd59 molecule (cd59 blood group))
F: None of the above. | E |
<Instruct>: Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', select the correct biomedical concept corresponding to 'mirl'. Answer using one of the provided options. | <Options>: A: minute-like (drosophila melanogaster) (aka minute-like)
B: mical-like (drosophila melanogaster) (aka mical-like)
C: mir (drosophila melanogaster) (miranda (drosophila melanogaster)) (aka miranda)
D: mirl (homo sapiens) (aka cd59 molecule (cd59 blood group))
E: mir (homo sapiens) (myosin regulatory light chain interacting protein (homo sapiens)) (aka myosin regulatory light chain interacting protein)
F: None of the above. | D |
<Instruct>: Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', select the correct biomedical concept corresponding to 'protectin'. Answer using one of the provided options. | <Options>: A: proprotein convertase subtilisin/kexin type 1 inhibitor (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
B: recoverin (homo sapiens) (aka recoverin)
C: serp1 (homo sapiens) (aka stress associated endoplasmic reticulum protein 1)
D: placentin (homo sapiens) (aka insulin like 4)
E: serpinh2 (homo sapiens) (aka serpin family h member 1)
F: None of the above. | F |
<Instruct>: Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', select the correct biomedical concept corresponding to 'protectin'. Answer using one of the provided options. | <Options>: A: fallotein (homo sapiens) (aka platelet derived growth factor c)
B: proprotein convertase subtilisin/kexin type 1 inhibitor (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
C: serp1 (homo sapiens) (aka stress associated endoplasmic reticulum protein 1)
D: sod (homo sapiens) (aka superoxide dismutase 1)
E: serpinh1 (homo sapiens) (aka serpin family h member 1)
F: None of the above. | F |
<Instruct>: Given the context 'The structure of the CD59 gene is very similar to that encoding Ly-6, a murine glycoprotein with which CD59 has some structural similarity.', select the correct biomedical concept corresponding to 'cd59'. Answer using one of the provided options. | <Options>: A: cd59 (homo sapiens) (aka cd59 molecule (cd59 blood group))
B: cd55 (homo sapiens) (aka cd55 molecule (cromer blood group))
C: cd51 (homo sapiens) (aka integrin subunit alpha v)
D: cd54 (homo sapiens) (aka intercellular adhesion molecule 1)
E: cd52 molecule (homo sapiens) (aka cd52 molecule)
F: None of the above. | A |
<Instruct>: Given the context 'The structure of the CD59 gene is very similar to that encoding Ly-6, a murine glycoprotein with which CD59 has some structural similarity.', select the correct biomedical concept corresponding to 'ly-6'. Answer using one of the provided options. | <Options>: A: slam family member 7 (homo sapiens) (aka slam family member 7)
B: lymphocyte antigen 6 family member h (homo sapiens) (aka lymphocyte antigen 6 family member h)
C: ly5 (homo sapiens) (aka protein tyrosine phosphatase receptor type c)
D: lymphocyte antigen 6 family member s (homo sapiens) (aka lymphocyte antigen 6 family member s)
E: slam family member 6 (homo sapiens) (aka slam family member 6)
F: None of the above. | F |
<Instruct>: Given the context 'The structure of the CD59 gene is very similar to that encoding Ly-6, a murine glycoprotein with which CD59 has some structural similarity.', select the correct biomedical concept corresponding to 'cd59'. Answer using one of the provided options. | <Options>: A: cd5 molecule (homo sapiens) (aka cd5 molecule)
B: cd58 (homo sapiens) (aka cd58 molecule)
C: cd59 (homo sapiens) (aka cd59 molecule (cd59 blood group))
D: cd54 (homo sapiens) (aka intercellular adhesion molecule 1)
E: cd52 (homo sapiens) (aka cd52 molecule)
F: None of the above. | C |
<Instruct>: Given the context 'The striking similarity in gene structure is further evidence that the two proteins belong to a superfamily of proteins that may also include the urokinase plasminogen-activator receptor and a squid glycoprotein of unknown function.', select the correct biomedical concept corresponding to 'urokinase plasminogen-activator receptor'. Answer using one of the provided options. | <Options>: A: urokinase plasminogen activator surface receptor-like (danio rerio) (aka urokinase plasminogen activator surface receptor-like)
B: plasminogen activator, urokinase receptor (homo sapiens) (aka plasminogen activator, urokinase receptor)
C: plasminogen activator, urokinase (homo sapiens) (aka plasminogen activator, urokinase)
D: plasminogen activator, urokinase receptor (rattus norvegicus) (aka plasminogen activator, urokinase receptor)
E: plasminogen activator, urokinase receptor (xenopus tropicalis) (aka plasminogen activator, urokinase receptor)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning and chromosome mapping of the human interleukin-1 receptor antagonist gene.
', select the correct biomedical concept corresponding to 'interleukin-1 receptor antagonist'. Answer using one of the provided options. | <Options>: A: interleukin 36 receptor antagonist (homo sapiens) (aka interleukin 36 receptor antagonist)
B: il1rn (homo sapiens) (aka interleukin 1 receptor antagonist)
C: interleukin 1 receptor antagonist (mus musculus) (aka interleukin 1 receptor antagonist)
D: il11ra (homo sapiens) (aka interleukin 11 receptor subunit alpha)
E: il1rp1 (homo sapiens) (aka interleukin 37)
F: None of the above. | B |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.