instruction stringlengths 225 2.35k | input stringlengths 89 1.5k | response stringclasses 698 values |
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<Instruct>: Given the context 'The initial report by Hirano et al. identified kinectin by screening an aplastic anemia patient for candidate antigens using a Clontech human fetal liver cDNA expression library and it was concluded that seven out of 18 aplastic anemia patients were positive for anti-kinectin while none of the normal or disease controls had this antibody', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; human; patients]
<Options>: A: homo (humans) (aka homo)
B: birds (aka aves)
C: homo sapiens (human) (aka homo sapiens)
D: primate (aka primates)
E: suborder
F: biota (aka cellular organisms)
G: mus <genus> (mice (aka mus <genus>))
H: mouse (aka mus musculus)
I: goes
J: cancer
K: other (aka unidentified)
L: macrobiotus sapiens
M: None of the above. | [C; C; C] |
<Instruct>: Given the context 'The initial report by Hirano et al. identified kinectin by screening an aplastic anemia patient for candidate antigens using a Clontech human fetal liver cDNA expression library and it was concluded that seven out of 18 aplastic anemia patients were positive for anti-kinectin while none of the normal or disease controls had this antibody', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; human; patients]
<Options>: A: goes
B: suborder
C: biota (aka cellular organisms)
D: mus <genus> (mice (aka mus <genus>))
E: homo (humans) (aka homo)
F: mouse (aka mus musculus)
G: birds (aka aves)
H: primate (aka primates)
I: macrobiotus sapiens
J: cancer
K: other (aka unidentified)
L: None of the above. | [L; L; L] |
<Instruct>: Given the context 'The initial report by Hirano et al. identified kinectin by screening an aplastic anemia patient for candidate antigens using a Clontech human fetal liver cDNA expression library and it was concluded that seven out of 18 aplastic anemia patients were positive for anti-kinectin while none of the normal or disease controls had this antibody', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; human; patients]
<Options>: A: kingdom
B: this
C: genus
D: mus <genus> (mice (aka mus <genus>))
E: placental mammals (aka eutheria)
F: species
G: animals (aka metazoa)
H: humans (aka homo)
I: isolate
J: aides
K: mammals (aka mammalia)
L: human (aka homo sapiens)
M: subsection
N: None of the above. | [L; L; L] |
<Instruct>: Given the context 'In their recent report, Hirano et al. reported that anti-kinectin antibodies were found in 39% of aplastic anemia patients from the United States but only in three out of 30 (10%) cases in Japan [38].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: probles
C: humans (aka homo)
D: goes
E: aides
F: None of the above. | [A] |
<Instruct>: Given the context 'In our study reported here, kinectin antibodies were only detected in BD patients and not in normal controls and SLE and SjS disease controls.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: circe
B: cancer
C: probles
D: homo sapiens (human) (aka homo sapiens)
E: goes
F: None of the above. | [D] |
<Instruct>: Given the context 'None of the BD patients with anti-kinectin had signs of HCC or aplastic anemia at the time of diagnosis and at up to 4 years of follow-up.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: kingdom
C: species
D: mouse (aka mus musculus)
E: cancer
F: None of the above. | [A] |
<Instruct>: Given the context 'Giantin, the highest molecular weight Golgi autoantigen reported, is the predominant target of human anti-Golgi complex antibodies and multiple non-cross-reactive epitopes have been mapped spanning the 350 kDa protein', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: genus
B: species
C: mammals (aka mammalia)
D: human (aka homo sapiens)
E: macrobiotus sapiens
F: None of the above. | [D] |
<Instruct>: Given the context 'Conclusion
Here we report the detection of kinectin autoantibody in 23% of Chinese patients with BD.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patients]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: goes
C: human (aka homo sapiens)
D: kingdom
E: cancer
F: None of the above. | [C] |
<Instruct>: Given the context 'In an effort to clarify the association of BD with antibody to kinectin, it is essential to measure antibody to kinectin in larger patient populations including both BD, probable BD and important autoimmune rheumatic diseases such as SLE, SjS, rheumatoid arthritis etc., as well as those diseases not easily differentiated from BD, such as recurrent aphthous oral ulcer, Reiter's syndrome, inflammatory bowel diseases etc.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: human (aka homo sapiens)
B: mouse (aka mus musculus)
C: cancer
D: humans (aka homo)
E: probles
F: None of the above. | [A] |
<Instruct>: Given the context 'A novel DNA-binding protein modulating methicillin resistance in Staphylococcus aureus
Abstract
Background
Methicillin resistance in Staphylococcus aureus is conferred by the mecA-encoded penicillin-binding protein PBP2a.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [staphylococcus aureus]
<Options>: A: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
B: staphylococcus epidermidis (staphylococcus epidermidis albus) (aka staphylococcus epidermidis)
C: staphylococcus sp. s
D: staphylococcus (aurococcus) (aka staphylococcus)
E: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
F: None of the above. | [A] |
<Instruct>: Given the context 'A novel DNA-binding protein modulating methicillin resistance in Staphylococcus aureus
Abstract
Background
Methicillin resistance in Staphylococcus aureus is conferred by the mecA-encoded penicillin-binding protein PBP2a.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [staphylococcus aureus]
<Options>: A: staphylococcus sp. s
B: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
C: staphylococcus (aurococcus) (aka staphylococcus)
D: staphylococcus epidermidis (staphylococcus epidermidis albus) (aka staphylococcus epidermidis)
E: None of the above. | [E] |
<Instruct>: Given the context 'Nonpolar deletion of SA1665, in heterogeneously methicillin resistant S. aureus (MRSA) of different genetic backgrounds, increased methicillin resistance levels in a strain dependent manner.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus; mrsa]
<Options>: A: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
B: staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300) (aka staphylococcus aureus subsp. aureus usa300)
C: staphylococcus simulans bv. staphylolyticus (staphylococcus simulans staphylolyticus) (aka staphylococcus simulans bv. staphylolyticus)
D: staphylococcus aureus m2
E: micrococcus pyogenes (aka staphylococcus aureus)
F: staphylococcus (aurococcus) (aka staphylococcus)
G: staphylococcus sp. s
H: staphylococcus aureus subsp. aureus strain mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
I: staphylococcus group (aka staphylococcaceae)
J: None of the above. | [E; E] |
<Instruct>: Given the context 'Nonpolar deletion of SA1665, in heterogeneously methicillin resistant S. aureus (MRSA) of different genetic backgrounds, increased methicillin resistance levels in a strain dependent manner.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus; mrsa]
<Options>: A: staphylococcus aureus m1
B: micrococcus aureus (aka staphylococcus aureus)
C: staphylococcus sp. s
D: staphylococcus (aurococcus) (aka staphylococcus)
E: staphylococcus staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
F: staphylococcus simulans bv. staphylolyticus (staphylococcus simulans staphylolyticus) (aka staphylococcus simulans bv. staphylolyticus)
G: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
H: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
I: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus aureus pa)
J: None of the above. | [B; B] |
<Instruct>: Given the context 'Conclusion
SA1665 is a new chromosomal factor which influences methicillin resistance in MRSA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus simulans bv. staphylolyticus (staphylococcus simulans staphylolyticus) (aka staphylococcus simulans bv. staphylolyticus)
B: staphylococcus pyogenes aureus (aka staphylococcus aureus)
C: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
D: staphylococcus aureus subsp. aureus strain usa300 (aka staphylococcus aureus subsp. aureus usa300)
E: staphylococcus aureus subsp. aureus str. mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
F: None of the above. | [B] |
<Instruct>: Given the context 'Background
Methicillin resistant S. aureus (MRSA) are an ever increasing threat, both in clinical settings and more recently as an emerging community acquired pathogen.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus; mrsa]
<Options>: A: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
B: staphylococcus (aurococcus) (aka staphylococcus)
C: micrococcus epidermidis (aka staphylococcus epidermidis)
D: staphylococcus aureus subsp. aureus str. usa300 (aka staphylococcus aureus subsp. aureus usa300)
E: staphylococcus group (aka staphylococcaceae)
F: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus aureus pa)
G: staphylococcus aureus m2
H: micrococcus pyogenes (aka staphylococcus aureus)
I: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
J: None of the above. | [H; H] |
<Instruct>: Given the context 'Background
Methicillin resistant S. aureus (MRSA) are an ever increasing threat, both in clinical settings and more recently as an emerging community acquired pathogen.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus; mrsa]
<Options>: A: staphylococcus aureus m2
B: staphylococcus aureus m1
C: staphylococcus sp. s
D: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
E: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
F: staphylococcus aureus strain pa (aka staphylococcus aureus pa)
G: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
H: 'staphylococcus faecalis' (aka staphylococcus faecalis)
I: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
J: None of the above. | [D; D] |
<Instruct>: Given the context 'In S. aureus, methicillin resistance is conferred by an acquired, β-lactam-insensitive penicillin-binding protein (PBP), PBP2a', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus]
<Options>: A: staphylococcus sp. s
B: staphylococcus group (aka staphylococcaceae)
C: staphylococcus simulans bv. staphylolyticus (staphylococcus simulans staphylolyticus) (aka staphylococcus simulans bv. staphylolyticus)
D: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
E: staphylococcus (aurococcus) (aka staphylococcus)
F: None of the above. | [D] |
<Instruct>: Given the context 'In S. aureus, methicillin resistance is conferred by an acquired, β-lactam-insensitive penicillin-binding protein (PBP), PBP2a', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus]
<Options>: A: staphylococcus simulans bv. staphylolyticus (staphylococcus simulans staphylolyticus) (aka staphylococcus simulans bv. staphylolyticus)
B: staphylococcus (aurococcus) (aka staphylococcus)
C: staphylococcus sp. s
D: staphylococcus group (aka staphylococcaceae)
E: None of the above. | [E] |
<Instruct>: Given the context 'Heterogeneously resistant MRSA, when exposed to β-lactam antibiotics, segregate highly resistant subpopulations, which are much more resistant than the majority of the cells [10].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
B: staphylococcus simulans staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
C: micrococcus aureus (aka staphylococcus aureus)
D: staphylococcus aureus m2
E: staphylococcus aureus subsp. aureus str. usa300 (aka staphylococcus aureus subsp. aureus usa300)
F: None of the above. | [C] |
<Instruct>: Given the context 'The vast MIC differences between MRSA strains, the population heterogeneity within single strains and the dependence of resistance levels on external factors are reflected in these many structural genes and global regulators, which can influence resistance levels.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus strain mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
B: staphylococcus aureus m2
C: staphylococcus aureus m1
D: staphylococcus pyogenes aureus (aka staphylococcus aureus)
E: staphylococcus aureus subsp. aureus str. usa300 (aka staphylococcus aureus subsp. aureus usa300)
F: None of the above. | [D] |
<Instruct>: Given the context 'While typically considered nosocomial pathogens, new faster growing and apparently more virulent MRSA have begun spreading in the community.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: micrococcus pyogenes (aka staphylococcus aureus)
B: staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300) (aka staphylococcus aureus subsp. aureus usa300)
C: staphylococcus aureus m2
D: staphylococcus aureus m1
E: staphylococcus aureus subsp. aureus strain mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
F: None of the above. | [A] |
<Instruct>: Given the context 'Interestingly, these emerging strains often express very low methicillin resistance, e.g. the MRSA clone spreading amongst intravenous drug users in the Zurich area, which has an in vitro doubling time of 25 min, but oxacillin MICs of only 0.5 to 4 μg/ml', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus pyogenes aureus (aka staphylococcus aureus)
B: staphylococcus aureus str. pa (aka staphylococcus aureus pa)
C: staphylococcus aureus m2
D: staphylococcus aureus subsp. aureus mrsa_pr1 (staphylococcus aureus subsp. aureus strain mrsa_pr1) (aka staphylococcus aureus subsp. aureus mrsa_pr1)
E: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
F: None of the above. | [A] |
<Instruct>: Given the context 'To identify potential factors involved in mecA regulation or methicillin resistance levels in such an extremely low level resistant MRSA, we performed DNA-binding protein purification assays, using the mecA operator region as bait.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
B: staphylococcus aureus subsp. aureus str. mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
C: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus aureus pa)
D: staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300) (aka staphylococcus aureus subsp. aureus usa300)
E: micrococcus aureus (aka staphylococcus aureus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Results
Identification of SA1665
MRSA strain CHE482 is the type strain for the so-called "drug clone" spreading amongst intravenous drug users in the Zurich area', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus aureus pa)
B: staphylococcus aureus m2
C: staphylococcus aureus subsp. aureus str. usa300 (aka staphylococcus aureus subsp. aureus usa300)
D: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
E: staphylococcus aureus subsp. aureus mrsa_pr1 (staphylococcus aureus subsp. aureus strain mrsa_pr1) (aka staphylococcus aureus subsp. aureus mrsa_pr1)
F: None of the above. | [D] |
<Instruct>: Given the context 'However, like most other low-level resistant MRSA, it can segregate a small proportion of higher resistant subclones in the presence of β-lactams.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus simulans staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
B: staphylococcus aureus m1
C: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
D: staphylococcus aureus str. pa (aka staphylococcus aureus pa)
E: staphylococcus pyogenes aureus (aka staphylococcus aureus)
F: None of the above. | [E] |
<Instruct>: Given the context 'We hypothesized that regulation of methicillin resistance in such low-level resistant clonal lineages may differ qualitatively from classical heterogeneously- or highly-resistant MRSA.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus strain mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
B: staphylococcus aureus subsp. aureus str. usa300 (aka staphylococcus aureus subsp. aureus usa300)
C: staphylococcus aureus m1
D: staphylococcus aureus str. pa (aka staphylococcus aureus pa)
E: micrococcus aureus (aka staphylococcus aureus)
F: None of the above. | [E] |
<Instruct>: Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus; s. haemolyticus; s. epidermidis; s. saprophyticus]
<Options>: A: annulatascus saprophyticus
B: actinobacillus equuli subsp. haemolyticus (actinobacillus equuli-like) (aka actinobacillus equuli subsp. haemolyticus)
C: brevibacterium epidermidis
D: streptomyces saprophyticus
E: micrococcus epidermidis (aka staphylococcus epidermidis)
F: staphylococcus casei (staphylococcus succinus subsp. casei) (aka staphylococcus casei)
G: staphylococcus haemolyticus
H: staphylococcus group (aka staphylococcaceae)
I: haemophilus parahaemolyticus
J: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
K: staphylococcus hominis subsp. hominis
L: staphylococcus epidermidis str. cons (aka staphylococcus epidermidis cons)
M: staphylococcus simulans bv. staphylolyticus (staphylococcus simulans staphylolyticus) (aka staphylococcus simulans bv. staphylolyticus)
N: brachybacterium epidermidis
O: streptococcus humanilactis
P: staphylococcus saprophyticus (staphylococcus saprophyticus subsp. bovis) (aka staphylococcus saprophyticus)
Q: staphylococcus staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
R: staphylococcus pyogenes aureus (aka staphylococcus aureus)
S: staphylococcus sp. s
T: staphylococcus hominis
U: None of the above. | [R; G; E; P] |
<Instruct>: Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus; s. haemolyticus; s. epidermidis; s. saprophyticus]
<Options>: A: bacillus x (aka haemophilus haemolyticus)
B: staphylococcus hominis subsp. hominis
C: streptococcus caprinus (aka streptococcus gallolyticus)
D: roussoella saprophytica
E: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
F: staphylococcus haemolyticus
G: staphylococcus sp. u
H: staphylococcus pyogenes aureus (aka staphylococcus aureus)
I: staphylococcus staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
J: staphylococcus group (aka staphylococcaceae)
K: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus aureus pa)
L: streptococcus hominis
M: albococcus epidermidis (aka staphylococcus epidermidis)
N: staphylococcus (aurococcus) (aka staphylococcus)
O: streptobacterium casei (aka lacticaseibacillus casei)
P: brachybacterium epidermidis
Q: staphylococcus aureus subsp. anaerobius (aka staphylococcus aureus)
R: enterococcus saccharolyticus subsp. saccharolyticus
S: staphylococcus saprophyticus subsp. bovis (aka staphylococcus saprophyticus)
T: None of the above. | [Q; F; M; S] |
<Instruct>: Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus; s. haemolyticus; s. epidermidis; s. saprophyticus]
<Options>: A: staphylococcus sp. s
B: staphylococcus epidermidis str. cons (aka staphylococcus epidermidis cons)
C: staphylococcus (aurococcus) (aka staphylococcus)
D: micrococcus epidermidis (aka staphylococcus epidermidis)
E: streptococcus gallolyticus subsp. gallolyticus
F: annulatascus saprophyticus
G: albococcus epidermidis (aka staphylococcus epidermidis)
H: staphylococcus saprophyticus (staphylococcus saprophyticus subsp. bovis) (aka staphylococcus saprophyticus)
I: haemophilus parahaemolyticus
J: streptococcus saccharolyticus (aka enterococcus saccharolyticus)
K: staphylococcus haemolyticus
L: brachybacterium epidermidis
M: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
N: actinobacillus equuli subsp. haemolyticus (actinobacillus equuli-like) (aka actinobacillus equuli subsp. haemolyticus)
O: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
P: bacillus x (aka haemophilus haemolyticus)
Q: staphylococcus pasteuri
R: micrococcus aureus (aka staphylococcus aureus)
S: streptococcus humanilactis
T: None of the above. | [O; K; G; H] |
<Instruct>: Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus; s. haemolyticus; s. epidermidis; s. saprophyticus]
<Options>: A: streptococcus humanilactis
B: bacillus x (aka haemophilus haemolyticus)
C: micrococcus aureus (aka staphylococcus aureus)
D: staphylococcus saprophyticus (staphylococcus saprophyticus subsp. bovis) (aka staphylococcus saprophyticus)
E: annulatascus saprophyticus
F: actinobacillus equuli subsp. haemolyticus (actinobacillus equuli-like) (aka actinobacillus equuli subsp. haemolyticus)
G: streptococcus saccharolyticus (aka enterococcus saccharolyticus)
H: staphylococcus epidermidis str. cons (aka staphylococcus epidermidis cons)
I: staphylococcus (aurococcus) (aka staphylococcus)
J: streptococcus gallolyticus subsp. gallolyticus
K: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
L: haemophilus parahaemolyticus
M: staphylococcus pasteuri
N: brachybacterium epidermidis
O: micrococcus epidermidis (aka staphylococcus epidermidis)
P: staphylococcus sp. s
Q: staphylococcus haemolyticus
R: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
S: None of the above. | [R; Q; S; D] |
<Instruct>: Given the context 'The amino acid sequence of SA1665 showed 100% identity amongst S. aureus database sequences and 97–98% identity amongst other staphylococci, including S. haemolyticus, S. epidermidis and S. saprophyticus, indicating that SA1665 is highly conserved.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. aureus; s. haemolyticus; s. epidermidis; s. saprophyticus]
<Options>: A: staphylococcus haemolyticus
B: macrococcoides epidermidis (aka macrococcus epidermidis)
C: staphylococcus group (aka staphylococcaceae)
D: streptococcus sp. group b (aka streptococcus sp. 'group b')
E: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
F: micrococcus epidermidis (aka staphylococcus epidermidis)
G: staphylococcus epidermidis (staphylococcus epidermidis albus) (aka staphylococcus epidermidis)
H: staphylococcus hominis
I: staphylococcus saprophyticus subsp. bovis (aka staphylococcus saprophyticus)
J: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
K: streptobacterium casei (aka lacticaseibacillus casei)
L: staphylococcus (aurococcus) (aka staphylococcus)
M: micrococcus aureus (aka staphylococcus aureus)
N: staphylococcus succinus subsp. casei (aka staphylococcus casei)
O: actinobacillus equuli subsp. haemolyticus (actinobacillus equuli-like) (aka actinobacillus equuli subsp. haemolyticus)
P: staphylococcus aureus str. pa (aka staphylococcus aureus pa)
Q: haemophilus haemolyticus (bacillus x) (aka haemophilus haemolyticus)
R: chromobacterium haemolyticum
S: staphylococcus hominis subsp. hominis
T: staphylococcus simulans staphylolyticus (aka staphylococcus simulans bv. staphylolyticus)
U: None of the above. | [J; A; F; I] |
<Instruct>: Given the context 'Conversely, there were no orfs highly similar to SA1665 found in other bacterial species, with the most similar sequences found in Bacillus licheniformis DSM13 and Desulfitobacterium hafniense Y51, which shared only 64% and 59% similarity, respectively.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bacillus licheniformis; desulfitobacterium hafniense y51]
<Options>: A: desulfococcus sp. dsm 8541
B: desulfitobacterium dehalogenans dsm 9161 (aka desulfitobacterium dehalogenans atcc 51507)
C: sulfitobacter sp. sa51
D: bacillus subtilis subsp. niger (bacillus subtilis var. niger) (aka bacillus subtilis subsp. niger)
E: bacillus sp. ly
F: clostridium licheniforme (aka bacillus licheniformis)
G: sulfitobacter sp. sl51
H: bacillus licheniformis dsm 13 (aka bacillus licheniformis dsm 13 = atcc 14580)
I: bacillus licheniformis f1-1
J: desulfitobacterium hafniense y51 (desulfitobacterium hafniense strain y51) (aka desulfitobacterium hafniense y51)
K: None of the above. | [F; J] |
<Instruct>: Given the context 'Conversely, there were no orfs highly similar to SA1665 found in other bacterial species, with the most similar sequences found in Bacillus licheniformis DSM13 and Desulfitobacterium hafniense Y51, which shared only 64% and 59% similarity, respectively.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [bacillus licheniformis; desulfitobacterium hafniense y51]
<Options>: A: omphalina licheniformis
B: desulfitobacterium hafniense str. y51 (aka desulfitobacterium hafniense y51)
C: clostridium licheniforme (aka bacillus licheniformis)
D: bacillus licheniformis f1-1
E: sulfitobacter sp. sa51
F: sulfitobacter sp. sl51
G: bacillus amylosacchariticus (aka bacillus subtilis subsp. amylosacchariticus)
H: bacillus licheniformis atcc 14580 (aka bacillus licheniformis dsm 13 = atcc 14580)
I: desulfitobacterium frappieri (aka desulfitobacterium hafniense)
J: desulfitobacterium hafniense dsm 13498 (aka desulfitobacterium hafniense dp7)
K: None of the above. | [C; B] |
<Instruct>: Given the context 'Crude protein extracts of E. coli strain BL21, carrying the empty plasmid (pET28nHis6) or pME20 (pET28nHis6-SA1665) which expressed nHis6-SA1665 upon induction with IPTG, were incubated with the 161-bp biotinylated-DNA fragment previously used as bait in the DNA-binding protein assay.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli strain bl21]
<Options>: A: escherichia coli mg1657 (escherichia coli strain mg1657) (aka escherichia coli mg1657)
B: escherichia coli strain bl21(de3) (aka escherichia coli bl21(de3))
C: escherichia coli bw25113 (escherichia coli strain bw25113) (aka escherichia coli bw25113)
D: escherichia coli mg1655 (aka escherichia coli str. k-12 substr. mg1655)
E: escherichia coli bl21 (escherichia coli strain bl21) (aka escherichia coli bl21)
F: None of the above. | [E] |
<Instruct>: Given the context 'Effect of SA1665 deletion on β-lactam resistance
To analyse the effect of SA1665 inactivation on methicillin resistance, nonpolar markerless deletions of SA1665 (Figure 1B) were constructed in a selection of clinical MRSA isolates, which varied in their genetic background, SCCmec type, and mecA regulation [24].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus str. mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
B: staphylococcus aureus subsp. aureus str. usa300 (aka staphylococcus aureus subsp. aureus usa300)
C: staphylococcus aureus m1
D: staphylococcus aureus m2
E: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Effect of SA1665 deletion on β-lactam resistance
To analyse the effect of SA1665 inactivation on methicillin resistance, nonpolar markerless deletions of SA1665 (Figure 1B) were constructed in a selection of clinical MRSA isolates, which varied in their genetic background, SCCmec type, and mecA regulation [24].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus m1
B: staphylococcus aureus m2
C: staphylococcus aureus subsp. aureus str. mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
D: staphylococcus aureus subsp. aureus str. usa300 (aka staphylococcus aureus subsp. aureus usa300)
E: None of the above. | [E] |
<Instruct>: Given the context 'Discussion
Methicillin resistance in MRSA is primarily dependent on the presence of the mecA gene, however, resistance levels are generally governed by strain-specific factors including mecA regulatory elements and other chromosomal fem/aux factors which either enhance or repress the expression of resistance.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus str. mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
B: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
C: staphylococcus aureus subsp. aureus str. usa300 (aka staphylococcus aureus subsp. aureus usa300)
D: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
E: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus aureus pa)
F: None of the above. | [D] |
<Instruct>: Given the context 'The impact of deleting SA1665 in MRSA was extremely strain specific, underlining the importance of the genetic background in governing the final methicillin resistance levels of MRSA, and demonstrating the large genomic variability between different strain lineages.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus pyogenes aureus (aka staphylococcus aureus)
B: staphylococcus aureus m2
C: staphylococcus aureus subsp. aureus mrsa131 (staphylococcus aureus subsp. aureus strain mrsa131) (aka staphylococcus aureus subsp. aureus mrsa131)
D: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
E: staphylococcus aureus pa (staphylococcus aureus strain pa) (aka staphylococcus aureus pa)
F: None of the above. | [A] |
<Instruct>: Given the context 'Conclusion
SA1665 is a previously uncharacterised DNA-binding protein that has a negative effect on β-lactam resistance in MRSA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus strain mrsa_pr1 (aka staphylococcus aureus subsp. aureus mrsa_pr1)
B: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
C: staphylococcus aureus subsp. aureus usa300 (staphylococcus aureus subsp. aureus strain usa300) (aka staphylococcus aureus subsp. aureus usa300)
D: staphylococcus aureus m2
E: micrococcus pyogenes (aka staphylococcus aureus)
F: None of the above. | [E] |
<Instruct>: Given the context 'However, while nonpolar deletion of SA1665 was shown to increase oxacillin resistance levels in several heterogeneously resistant MRSA, its deletion had no effect on mecA transcription or PBP2a production.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus strain usa300 (aka staphylococcus aureus subsp. aureus usa300)
B: micrococcus pyogenes (aka staphylococcus aureus)
C: staphylococcus aureus m1
D: staphylococcus aureus str. pa (aka staphylococcus aureus pa)
E: staphylococcus aureus subsp. aureus mrsa_pr1 (staphylococcus aureus subsp. aureus strain mrsa_pr1) (aka staphylococcus aureus subsp. aureus mrsa_pr1)
F: None of the above. | [B] |
<Instruct>: Given the context 'The resulting plasmid, pME20, was transformed into E. coli BL21 for expression of recombinant nHis6-SA1665 protein.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli bl21]
<Options>: A: escherichia virus de3
B: escherichia coli bw25113 (escherichia coli strain bw25113) (aka escherichia coli bw25113)
C: escherichia coli strain 1520 (aka escherichia coli 1520)
D: escherichia coli s17
E: escherichia coli bl21 (escherichia coli strain bl21) (aka escherichia coli bl21)
F: None of the above. | [E] |
<Instruct>: Given the context 'To maximise the abundance of soluble protein produced, cultures were grown in osmotic shock medium at 37°C (1 g/l NaCl, 16 g/l tryptone, 10 g/l yeast, 1 M sorbitol, 10 mM betaine, modified from [33]) to an OD600 nm of 0.5, cooled briefly on ice, then induced by adding 100 μM IPTG and growing overnight at 22°C.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yeast]
<Options>: A: saccharomyces cf. cerevisiae
B: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces cerevisiae)
C: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
D: saccharomyces cerevisiae x saccharomyces mikatae
E: saccharomyces cf. cerevisiae/paradoxus (saccharomyces cerevisiae or paradoxus) (aka saccharomyces cf. cerevisiae/paradoxus)
F: None of the above. | [B] |
<Instruct>: Given the context '[36].
Cloning of SA1665 for complementation
A 1533-bp DNA fragment, containing SA1665 together with 690-bp of upstream and 379-bp of downstream DNA, was amplified from strain CHE482 using primers me94BamHI/me94Asp718 (Table 2) and cloned into the E. coli/S. aureus shuttle vectors pAW17 and pBUS1 [37], creating the complementing plasmids pME26 and pME27, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli; s. aureus]
<Options>: A: enterobacteria (aka enterobacteriaceae)
B: enterobacteriaceae bacterium
C: bacterium coli (aka escherichia coli)
D: staphylococcus group (aka staphylococcaceae)
E: micrococcus pyogenes (aka staphylococcus aureus)
F: escherichia
G: escherichia phage
H: staphylococcus simulans bv. staphylolyticus (staphylococcus simulans staphylolyticus) (aka staphylococcus simulans bv. staphylolyticus)
I: micrococcus epidermidis (aka staphylococcus epidermidis)
J: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
K: None of the above. | [C; E] |
<Instruct>: Given the context '[36].
Cloning of SA1665 for complementation
A 1533-bp DNA fragment, containing SA1665 together with 690-bp of upstream and 379-bp of downstream DNA, was amplified from strain CHE482 using primers me94BamHI/me94Asp718 (Table 2) and cloned into the E. coli/S. aureus shuttle vectors pAW17 and pBUS1 [37], creating the complementing plasmids pME26 and pME27, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli; s. aureus]
<Options>: A: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
B: staphylococcus aureus str. pa (aka staphylococcus aureus pa)
C: micrococcus pyogenes (aka staphylococcus aureus)
D: escherichia phage
E: staphylococcus group (aka staphylococcaceae)
F: unspecified coliform bacterium
G: e. coli (aka escherichia coli)
H: escherichia coli (strain b) (aka escherichia coli b)
I: escherichia
J: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
K: None of the above. | [G; C] |
<Instruct>: Given the context '[36].
Cloning of SA1665 for complementation
A 1533-bp DNA fragment, containing SA1665 together with 690-bp of upstream and 379-bp of downstream DNA, was amplified from strain CHE482 using primers me94BamHI/me94Asp718 (Table 2) and cloned into the E. coli/S. aureus shuttle vectors pAW17 and pBUS1 [37], creating the complementing plasmids pME26 and pME27, respectively.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [e. coli; s. aureus]
<Options>: A: staphylococcus aureus str. pa (aka staphylococcus aureus pa)
B: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
C: unspecified coliform bacterium
D: escherichia
E: escherichia coli (strain b) (aka escherichia coli b)
F: staphylococcus group (aka staphylococcaceae)
G: escherichia phage
H: micrococcus pyogenes (aka staphylococcus aureus)
I: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
J: None of the above. | [J; H] |
<Instruct>: Given the context 'PBP2a detection was performed using monoclonal PBP2a antibody (1:20000) from the MRSA-screen kit (Denka Seiken).
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mrsa]
<Options>: A: staphylococcus aureus subsp. aureus str. usa300 (aka staphylococcus aureus subsp. aureus usa300)
B: micrococcus pyogenes (aka staphylococcus aureus)
C: staphylococcus aureus m1
D: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
E: staphylococcus aureus m2
F: None of the above. | [B] |
<Instruct>: Given the context 'The Caenorhabditis elegans genome contains monomorphic minisatellites and simple sequences.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [caenorhabditis elegans]
<Options>: A: caenorhabditis sp.
B: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
C: cyclostrongylus elegans
D: caenorhabditis
E: caenorhabditis drosophilae (rhabditis drosophilae) (aka caenorhabditis drosophilae)
F: None of the above. | [B] |
<Instruct>: Given the context 'Here we demonstrate the presence of sequences in the genome of the nematode Caenorhabditis elegans which are homologous to two sets of short sequence DNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [caenorhabditis elegans]
<Options>: A: elegans subgroup (in: mosquitos)
B: elegans subgroup (in: flies)
C: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
D: caenorhabditis vulgaris (aka caenorhabditis remanei)
E: drosophila elegans
F: None of the above. | [C] |
<Instruct>: Given the context 'Images
Volume 17 Number 23 1989 Nucleic Acids Research
The Caenorhabds elegans genome contains monomorphic minisatellites and simple sequences Andrd G.Uitterlinden, P.Eline Slagboom, Thomas E.Johnsonl and Jan Vijg
Department of Molecular Biology, TNO Institute for Experimental Gerontology, PO Box 5815, 2280 HV Rijswijk, The Netherlands and lInstitute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA
Received October 27, 1989; Accepted November 3, 1989
ABSTRACT
Many species have been shown to contain tandemly repeated short sequence DNA kinown as minisatellites and simple sequence motifs.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [caenorhabds elegans]
<Options>: A: theocolax elegans
B: uronema elegans
C: aplysinopsis elegans
D: rhabditis elegans (aka caenorhabditis elegans)
E: latrodectus elegans
F: None of the above. | [D] |
<Instruct>: Given the context 'Here we demonstrate the presence of sequences in the genome of the nematode Caenorhabditis elegans which are homologous to two sets of short sequence DNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [caenorhabditis elegans]
<Options>: A: rhabditis elegans (aka caenorhabditis elegans)
B: myzomyia elegans (aka anopheles elegans)
C: theocolax elegans
D: elegans subgroup (in: flies)
E: uronema elegans
F: None of the above. | [A] |
<Instruct>: Given the context 'Here we demonstrate that the genome of the nematode Caenorhabditis elegans contains sequences that are homologous to the minisatellite core sequence 33.6 (1) and to the simple sequence motif (AGC)n.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [caenorhabditis elegans]
<Options>: A: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
B: polyzonia elegans
C: caenorhabditis
D: elegans subgroup (in: flies)
E: drosophila elegans
F: None of the above. | [A] |
<Instruct>: Given the context 'Surprisingly, these sequences did not display polymorphism when two independent C. elegans strains, Bristol and Bergerac, were compared.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
B: elegans subgroup (in: mosquitos)
C: gongylostoma elegans elegans (clausilia elegans elegans) (aka gongylostoma elegans elegans)
D: caenorhabditis vulgaris (aka caenorhabditis remanei)
E: uca elegans (aka tubuca elegans)
F: None of the above. | [A] |
<Instruct>: Given the context 'Nucleic Acids Research
C. elegans
N 0$ 8
_ _
: , s , ..e :*. ,~ :::::
.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: uca elegans (aka tubuca elegans)
B: uronema elegans
C: caenorhabditis drosophilae (rhabditis drosophilae) (aka caenorhabditis drosophilae)
D: cyclostrongylus elegans
E: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
F: None of the above. | [E] |
<Instruct>: Given the context 'I and Eco RI digested genomic DNA isolated from the two C. elegans strains Bristol (N) and Bergerac (B).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: gongylostoma elegans elegans (clausilia elegans elegans) (aka gongylostoma elegans elegans)
B: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
C: caenorhabditis vulgaris (aka caenorhabditis remanei)
D: uca elegans (aka tubuca elegans)
E: cyclostrongylus elegans
F: None of the above. | [B] |
<Instruct>: Given the context 'In Figure 1 the hybridization patterns are shown of C. elegans genomic DNA digested with Hae II, Rsa I and Eco RI, and subsequently hybridized to minisatellite core probe 33.6, the simple sequence probe (AGC)n and Tcl.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: rhabditis elegans (aka caenorhabditis elegans)
B: caenorhabditis vulgaris (aka caenorhabditis remanei)
C: uca elegans (aka tubuca elegans)
D: caenorhabditis
E: elegans subgroup (in: mosquitos)
F: None of the above. | [A] |
<Instruct>: Given the context 'In Figure 1 the hybridization patterns are shown of C. elegans genomic DNA digested with Hae II, Rsa I and Eco RI, and subsequently hybridized to minisatellite core probe 33.6, the simple sequence probe (AGC)n and Tcl.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: caenorhabditis
B: elegans subgroup (in: mosquitos)
C: uca elegans (aka tubuca elegans)
D: caenorhabditis vulgaris (aka caenorhabditis remanei)
E: None of the above. | [E] |
<Instruct>: Given the context 'However, identical hybridization patterns for the two strains with the three enzymes tested indicated that in C. elegans these sequences are monomorphic (Fig. 1).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: caenorhabditis vulgaris (aka caenorhabditis remanei)
B: urocitellus elegans elegans (spermophilus elegans elegans) (aka urocitellus elegans elegans)
C: gongylostoma elegans elegans (clausilia elegans elegans) (aka gongylostoma elegans elegans)
D: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
E: bactris elegans
F: None of the above. | [D] |
<Instruct>: Given the context 'Based on the number of hybridizing bands we estimate the C. elegans genome to contain about 30 33.6 homologous loci and about 20 (AGC)n homologous loci.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: caromyxa elegans (aka mutinus elegans)
B: rhabditis elegans (aka caenorhabditis elegans)
C: caenorhabditis
D: bactris elegans
E: drosophila elegans
F: None of the above. | [B] |
<Instruct>: Given the context 'It should be noted, however, that at least in humans, a substantial part of the minisatellites detected by core probes also displays high levels of monomorphism as analysed by cloning (1) or by two-dimensional DNA fingerprinting (5).
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [humans]
<Options>: A: homo (humans) (aka homo)
B: animals (aka metazoa)
C: birds (aka aves)
D: hominidae (great apes) (aka hominidae)
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'Indeed, Eide and Anderson (7) showed that tandemly repeated duplications in the unc-54 gene of C. elegans revert at high frequencies.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: myzomyia elegans (aka anopheles elegans)
B: uronema elegans
C: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
D: caenorhabditis
E: bactris elegans
F: None of the above. | [C] |
<Instruct>: Given the context 'A more likely explanation for the monomorphic nature of the sequences detected with 33.6 and (AGC)n in C. elegans is selection against sequence variants at these loci.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: caenorhabditis drosophilae (rhabditis drosophilae) (aka caenorhabditis drosophilae)
B: zodarion elegans (enyo elegans) (aka zodarion elegans)
C: gongylostoma elegans elegans (clausilia elegans elegans) (aka gongylostoma elegans elegans)
D: caenorhabditis
E: rhabditis elegans (aka caenorhabditis elegans)
F: None of the above. | [E] |
<Instruct>: Given the context 'An important step in understanding this phenomenon will therefore be the isolation and analysis of individual homologous minisatellite and simple sequence loci from a genomic library of C. elegans.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [c. elegans]
<Options>: A: elegans subgroup (in: flies)
B: cyclostrongylus elegans
C: gongylostoma elegans elegans (clausilia elegans elegans) (aka gongylostoma elegans elegans)
D: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
E: caenorhabditis
F: None of the above. | [D] |
<Instruct>: Given the context 'In the second study, adult (3–6 m) BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: mus musculus (house mouse) (aka mus musculus)
C: mus castaneus (aka mus musculus castaneus)
D: peromyscus
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | [B] |
<Instruct>: Given the context 'On the third day, mice were also injected (i.p.) with saline or Escherichia coli LPS (0.33 mg/kg) and behavior (i.e., sickness and anhedonia) and markers of neuroinflammation (i.e., microglia activation and inflammatory cytokines) were determined.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; escherichia coli]
<Options>: A: peromyscus
B: mus musculus (house mouse) (aka mus musculus)
C: unspecified coliform bacterium
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: escherichia/shigella coli (aka escherichia coli)
F: escherichia phage
G: escherichia coli (strain b) (aka escherichia coli b)
H: escherichia sp.
I: mus (aka mus <subgenus>) (aka mus <subgenus>)
J: mus castaneus (aka mus musculus castaneus)
K: None of the above. | [B; E] |
<Instruct>: Given the context 'On the third day, mice were also injected (i.p.) with saline or Escherichia coli LPS (0.33 mg/kg) and behavior (i.e., sickness and anhedonia) and markers of neuroinflammation (i.e., microglia activation and inflammatory cytokines) were determined.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; escherichia coli]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: mouse (aka mus musculus)
C: bacteria (ex cavalier-smith 1987) (aka bacteria)
D: escherichia coli b (escherichia coli (strain b)) (aka escherichia coli b)
E: peromyscus
F: 'escherichia faecalis' (aka escherichia faecalis)
G: bacillus coli (aka escherichia coli)
H: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
I: enterobacteriaceae bacterium
J: mus cricetus (aka cricetus cricetus)
K: None of the above. | [B; G] |
<Instruct>: Given the context 'In the final study, adult and aged BALB/c mice were treated with the same minocycline and LPS injection regimen and markers of neuroinflammation were determined.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: house mouse (aka mus musculus)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus castaneus (aka mus musculus castaneus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | [B] |
<Instruct>: Given the context 'Moreover, minocycline facilitated the recovery from sickness behavior (i.e., anorexia, weight loss, and social withdrawal) and prevented anhedonia in adult mice challenged with LPS.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus domesticus (aka mus musculus domesticus)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus cricetus (aka cricetus cricetus)
D: mus musculus (house mouse) (aka mus musculus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [D] |
<Instruct>: Given the context 'Finally, in aged mice, where exaggerated neuroinflammation was elicited by LPS, minocycline pretreatment was still effective in markedly reducing mRNA levels of IL-1β, TLR2 and IDO in the hippocampus.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mus castaneus (aka mus musculus castaneus)
C: mouse (aka mus musculus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus sp. (mice (aka mus sp.))
F: None of the above. | [C] |
<Instruct>: Given the context 'Moreover, in the brain of rats, minocycline abrogates microglial expression of CD11b and MHC II through a protein kinase-c dependent mechanism [45].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rats]
<Options>: A: mus norvegicus (aka rattus norvegicus)
B: rattus sp. (rats (aka rattus sp.))
C: rattus (rats (aka rattus))
D: rattus rattoides (aka rattus pyctoris)
E: roof rat (aka rattus rattus)
F: None of the above. | [A] |
<Instruct>: Given the context 'Moreover, our data show that minocycline pretreatment attenuated LPS-induced weight loss, social withdrawal, and anhedonia in adult mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: house mouse (aka mus musculus)
B: mice (aka mus sp.) (aka mus sp.)
C: peromyscus
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [A] |
<Instruct>: Given the context 'The attenuation of sickness behavior was paralleled with minocycline dependent decrease in markers of neuroinflammation (IL-1β, TLR2, and IDO) in adult and aged mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: house mouse (aka mus musculus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mus sp. (mice (aka mus sp.))
D: peromyscus
E: mice (aka mus <genus>) (aka mus <genus>)
F: None of the above. | [A] |
<Instruct>: Given the context 'Methods
Animals
Male BALB/c mice, adults (3 month old) and juvenile (3–4 week old) were purchased from Harlan (Indianapolis, IN).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: house mouse (aka mus musculus)
B: mouse (aka mus <genus>)
C: mus cricetus (aka cricetus cricetus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | [A] |
<Instruct>: Given the context 'For age comparisons, male BALB/c mice (3–4 and 20–22 month old) were purchased from the National Institute on Aging specific pathogen free colony.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mouse (aka mus <genus>)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mouse (aka mus musculus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [C] |
<Instruct>: Given the context 'Upon arrival, mice were individually housed in polypropylene cages and maintained at 21°C under a 12 h light: 12 h dark cycle with ad libitum access to water and rodent chow.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: house mouse (aka mus musculus)
C: mice (aka mus sp.) (aka mus sp.)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [B] |
<Instruct>: Given the context 'Upon arrival, mice were individually housed in polypropylene cages and maintained at 21°C under a 12 h light: 12 h dark cycle with ad libitum access to water and rodent chow.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus <genus> (mice (aka mus <genus>))
B: mus castaneus (aka mus musculus castaneus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mice (aka mus sp.) (aka mus sp.)
E: None of the above. | [E] |
<Instruct>: Given the context 'At the end of each study, mice were examined postmortem for gross signs of disease (e.g., splenomeglia or tumors).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mus musculus (house mouse) (aka mus musculus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: western european house mouse (aka mus musculus domesticus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [B] |
<Instruct>: Given the context 'Data from mice determined to be unhealthy were excluded from analysis (< 5%).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: peromyscus
C: mice (aka mus <genus>) (aka mus <genus>)
D: eastern european house mouse (aka mus musculus musculus)
E: mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Mice were euthanized by CO2 asphyxiation and whole brains were collected.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: mouse (aka mus musculus)
C: mus castaneus (aka mus musculus castaneus)
D: western european house mouse (aka mus musculus domesticus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [B] |
<Instruct>: Given the context 'Sucrose preference
To assess sucrose preference, mice were provided two solutions, water or water supplemented with 2% sucrose, in 50 ml conical tubes with stoppers fitted with ball-type sipper tubes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus sp. (mice (aka mus sp.))
B: mus castaneus (aka mus musculus castaneus)
C: mouse (aka mus musculus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | [C] |
<Instruct>: Given the context 'Prior to testing conditions, all mice were acclimated to the two bottle test choice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: house mouse (aka mus musculus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus castaneus (aka mus musculus castaneus)
E: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
F: None of the above. | [B] |
<Instruct>: Given the context 'All mice drank both the water and the 2% sucrose solution, but preferred drinking the sucrose over the water (data not shown).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus castaneus (aka mus musculus castaneus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: house mouse (aka mus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [D] |
<Instruct>: Given the context 'On the day of testing, mice were fluid and food deprived for 2 h prior to testing [50].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: house mouse (aka mus musculus)
B: mus domesticus (aka mus musculus domesticus)
C: mus cricetus (aka cricetus cricetus)
D: peromyscus
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | [A] |
<Instruct>: Given the context 'In brief, mice were euthanized by CO2 asphyxiation and blood was collected by cardiac puncture into EDTA coated syringes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: mice (aka mus sp.) (aka mus sp.)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mouse (aka mus musculus)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | [D] |
<Instruct>: Given the context 'For all mouse studies, minocycline (Sigma, St. Louis, MO) was dissolved in sterile water and sonicated to ensure complete solubilization.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse]
<Options>: A: mus sp. (mice (aka mus sp.))
B: mouse (aka mus musculus)
C: western european house mouse (aka mus musculus domesticus)
D: mus cricetus (aka cricetus cricetus)
E: peromyscus
F: None of the above. | [B] |
<Instruct>: Given the context 'In the first mouse study, adult male BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; mice]
<Options>: A: mouse (aka mus musculus)
B: mus cricetus (aka cricetus cricetus)
C: mus (aka mus <genus>) (aka mus <genus>)
D: mice (aka mus sp.) (aka mus sp.)
E: mus molossinus (aka mus musculus molossinus)
F: mus castaneus (aka mus musculus castaneus)
G: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
H: mus <subgenus> (mus (aka mus <subgenus>))
I: mus (aka mus <subgenus>) (aka mus <subgenus>)
J: None of the above. | [A; A] |
<Instruct>: Given the context 'In the first mouse study, adult male BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mouse; mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus (aka mus <genus>) (aka mus <genus>)
C: western european house mouse (aka mus musculus domesticus)
D: mus musculus (house mouse) (aka mus musculus)
E: peromyscus
F: mice (aka mus <genus>) (aka mus <genus>)
G: mus <subgenus> (mus (aka mus <subgenus>))
H: mice (aka mus sp.) (aka mus sp.)
I: mus castaneus (aka mus musculus castaneus)
J: None of the above. | [D; D] |
<Instruct>: Given the context 'On the 3rd day, mice were also injected i.p. with saline or Escherichia coli LPS (0.33 mg/kg; serotype 0127:', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; escherichia coli]
<Options>: A: mus domesticus (aka mus musculus domesticus)
B: bacillus coli (aka escherichia coli)
C: mus castaneus (aka mus musculus castaneus)
D: mus cricetus (aka cricetus cricetus)
E: escherichia sp.
F: mus <genus> (mice (aka mus <genus>))
G: house mouse (aka mus musculus)
H: escherichia coli (strain b) (aka escherichia coli b)
I: escherichia coli 1a
J: enterobacteriaceae bacterium
K: None of the above. | [G; B] |
<Instruct>: Given the context 'On the 3rd day, mice were also injected i.p. with saline or Escherichia coli LPS (0.33 mg/kg; serotype 0127:', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice; escherichia coli]
<Options>: A: escherichia coli 1a
B: 'escherichia faecalis' (aka escherichia faecalis)
C: mus musculus (house mouse) (aka mus musculus)
D: western european house mouse (aka mus musculus domesticus)
E: peromyscus
F: eastern european house mouse (aka mus musculus musculus)
G: enterobacteriales (aka enterobacterales)
H: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
I: e. coli (aka escherichia coli)
J: escherichia coli b (escherichia coli (strain b)) (aka escherichia coli b)
K: None of the above. | [C; I] |
<Instruct>: Given the context 'The LPS dosage was selected because it elicits a proinflammatory cytokine response in the brain resulting in mild transient sickness behavior in adult mice [13,53].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus castaneus (aka mus musculus castaneus)
B: mice (aka mus sp.) (aka mus sp.)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: western european house mouse (aka mus musculus domesticus)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'In the second study, adult male BALB/c mice received an i.p. injection with vehicle or minocycline for three consecutive days.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mice (aka mus sp.) (aka mus sp.)
C: eastern european house mouse (aka mus musculus musculus)
D: mus domesticus (aka mus musculus domesticus)
E: house mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'In a related, but separate study, adult mice were treated with minocycline and LPS as described and anhedonia was assessed 24–39 h following i.p. injection of saline or LPS (0.33 mg/kg) (n = 15).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus musculus (house mouse) (aka mus musculus)
B: peromyscus
C: mice (aka mus <genus>) (aka mus <genus>)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [A] |
<Instruct>: Given the context 'In a related, but separate study, adult mice were treated with minocycline and LPS as described and anhedonia was assessed 24–39 h following i.p. injection of saline or LPS (0.33 mg/kg) (n = 15).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mice (aka mus <genus>) (aka mus <genus>)
B: peromyscus
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus castaneus (aka mus musculus castaneus)
E: None of the above. | [E] |
<Instruct>: Given the context 'In the third study, adult BALB/c mice were treated with minocycline and then LPS as described.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mouse (aka mus <genus>)
B: mus castaneus (aka mus musculus castaneus)
C: mus domesticus (aka mus musculus domesticus)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'Mice were euthanized by CO2 asphyxiation 4 later.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: western european house mouse (aka mus musculus domesticus)
E: house mouse (aka mus musculus)
F: None of the above. | [E] |
<Instruct>: Given the context 'In a final study, adult (3–4 month old) or aged (20–22 month old) male BALB/c mice were treated with minocycline and LPS as described and euthanized 4 h later.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mice (aka mus <genus>) (aka mus <genus>)
B: house mouse (aka mus musculus)
C: mus castaneus (aka mus musculus castaneus)
D: mus cricetus (aka cricetus cricetus)
E: mus sp. (mice (aka mus sp.))
F: None of the above. | [B] |
<Instruct>: Given the context 'LPS-induced TLR2 surface expression on microglia is reduced by minocycline
Because minocycline attenuated LPS-induced cytokine secretion and TLR2 mRNA expression in BV-2 cells we next sought to determine if minocycline suppresses markers of microglial activation in the brain of mice.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus (aka mus <genus>) (aka mus <genus>)
B: western european house mouse (aka mus musculus domesticus)
C: peromyscus
D: mouse (aka mus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | [D] |
<Instruct>: Given the context 'Mice were injected i.p.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: mus cricetus (aka cricetus cricetus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: house mouse (aka mus musculus)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | [D] |
<Instruct>: Given the context 'In this experiment, adult mice were treated with minocycline and LPS as described.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: western european house mouse (aka mus musculus domesticus)
B: eastern european house mouse (aka mus musculus musculus)
C: mice (aka mus <genus>) (aka mus <genus>)
D: house mouse (aka mus musculus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | [D] |
<Instruct>: Given the context 'For example, at 8 h post LPS, social exploration was reduced by 35% in minocycline pretreated mice given LPS compared to a 67% reduction in vehicle pretreated mice given LPS (P < 0.001).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mus castaneus (aka mus musculus castaneus)
C: mouse (aka mus musculus)
D: peromyscus
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | [C] |
<Instruct>: Given the context 'While minocycline administration alone reduced food intake and body weight in control mice (P < 0.05, for each), it also protected against LPS-associated anorexia (Mino × LPS interaction, F(1, 60)', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [mice]
<Options>: A: western european house mouse (aka mus musculus domesticus)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mouse (aka mus musculus)
D: peromyscus
E: mus sp. (mice (aka mus sp.))
F: None of the above. | [C] |
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