instruction stringlengths 225 2.35k | input stringlengths 89 1.5k | response stringclasses 698 values |
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<Instruct>: Given the context 'The ineffectiveness of tobramycin combination therapy in Streptococcus faecium endocarditis.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [streptococcus faecium]
<Options>: A: brachybacterium faecium
B: enterococcus florum
C: streptococcus durans (aka enterococcus durans)
D: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
E: enterococcus hirae
F: None of the above. | [D] |
<Instruct>: Given the context 'Abstract
A patient required mitral valve replacement following ineffective antibiotic treatment of enterococcal endocarditis caused by Streptococcus faecium.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; streptococcus faecium]
<Options>: A: subsection
B: homo sapiens (human) (aka homo sapiens)
C: corynebacterium faecium
D: streptococcus faecalis (aka enterococcus faecalis)
E: aides
F: humans (aka homo)
G: enterococcus hirae
H: proxys
I: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
J: enterococcus florum
K: None of the above. | [B; I] |
<Instruct>: Given the context 'Abstract
A patient required mitral valve replacement following ineffective antibiotic treatment of enterococcal endocarditis caused by Streptococcus faecium.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; streptococcus faecium]
<Options>: A: enterococcus hirae
B: enterococcus avium (streptococcus avium) (aka enterococcus avium)
C: corynebacterium faecium
D: probles
E: circe
F: clostridium faecium
G: streptococcus faecium (aka enterococcus faecium)
H: cancer
I: theraps
J: homo sapiens (human) (aka homo sapiens)
K: None of the above. | [J; G] |
<Instruct>: Given the context 'Initial failure of antibiotic therapy may be related to the known lack of in vitro and in vivo synergy between penicillin and tobramycin against S. faecium.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: enterococcus
B: streptococcus faecalis (aka enterococcus faecalis)
C: enterococcus hirae
D: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
E: streptococcus faecium subsp. casseliflavus (aka enterococcus casseliflavus)
F: None of the above. | [D] |
<Instruct>: Given the context 'THE YALE JOURNAL OF BIOLOGY AND MEDICINE 56 (1983), 243-249
The Ineffectiveness of Tobramycin Combination Therapy
in Streptococcus Faecium Endocarditis
JUDITH A. GOLDSTEIN, M.D.,a HOWARD COHEN, M.D.,a AND
FRANK J. BIA, M.D., M.P.H.a,b
aInfectious Disease Section of the Department of Medicine, and bThe Department of
Laboratory Medicine, Veterans Administration Medical Center,
West Haven, and Yale University School of Medicine,
New Haven, Connecticut
Received July 11, 1983
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [streptococcus faecium]
<Options>: A: clostridium faecium
B: streptococcus faecium (aka enterococcus faecium)
C: enterenecus faecium (aka candidatus enterenecus faecium)
D: streptococcus avium (aka enterococcus avium)
E: sphingobacterium faecium
F: None of the above. | [B] |
<Instruct>: Given the context 'A patient required mitral valve replacement following ineffective antibiotic treatment of enterococcal endocarditis caused by Streptococcusfaecium.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; streptococcusfaecium]
<Options>: A: streptococcus faecavium (aka candidatus streptococcus faecavium)
B: enterococcus florum
C: cancer
D: streptococcus durans (aka enterococcus durans)
E: enterococcus faecalis (streptococcus glycerinaceus) (aka enterococcus faecalis)
F: data
G: kingdom
H: this
I: streptococcus faecium (aka enterococcus faecium)
J: homo sapiens (human) (aka homo sapiens)
K: None of the above. | [J; I] |
<Instruct>: Given the context 'A patient required mitral valve replacement following ineffective antibiotic treatment of enterococcal endocarditis caused by Streptococcusfaecium.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; streptococcusfaecium]
<Options>: A: this
B: streptococcus durans (aka enterococcus durans)
C: homo sapiens (human) (aka homo sapiens)
D: circe
E: data
F: enterococcus plantarum
G: mouse (aka mus musculus)
H: 'staphylococcus faecalis' (aka staphylococcus faecalis)
I: streptococcus faecavium (aka candidatus streptococcus faecavium)
J: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
K: None of the above. | [C; J] |
<Instruct>: Given the context 'Initial failure of antibiotic therapy may be related to the known lack of in vitro and in vivo synergy between penicillin and tobramycin against S. faecium.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: enterococcus
B: enterococcus faecium e155
C: enterococcus hirae
D: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
E: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
F: None of the above. | [E] |
<Instruct>: Given the context 'The group D enterococci include three main species S. faecalis, S. faecium, and S. durans.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecalis; s. faecium; s. durans]
<Options>: A: bacteroides faecalis
B: streptococcus mutans
C: streptococcus faecalis (aka enterococcus faecalis)
D: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
E: streptococcus infantis
F: brachybacterium faecium
G: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
H: streptococcus ovis
I: streptococcus cecorum (aka enterococcus cecorum)
J: streptococcus humanilactis
K: enterococcus durans (streptococcus durans) (aka enterococcus durans)
L: enterococcus
M: enterococcus casseliflavus (streptococcus faecium subsp. casseliflavus) (aka enterococcus casseliflavus)
N: enterococcus plantarum
O: streptococcus suis
P: None of the above. | [C; G; K] |
<Instruct>: Given the context 'The group D enterococci include three main species S. faecalis, S. faecium, and S. durans.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecalis; s. faecium; s. durans]
<Options>: A: streptococcus faecalis (aka enterococcus faecalis)
B: streptococcus fermentans
C: 'escherichia faecalis' (aka escherichia faecalis)
D: streptococcus equi
E: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
F: streptococcus durans (aka enterococcus durans)
G: enterococcus
H: streptococcus entericus
I: streptococcus uberis
J: avispirillum faecium (aka candidatus avispirillum faecium)
K: sphingobacterium faecium
L: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
M: streptococcus faecium (aka enterococcus faecium)
N: enterenecus faecium (aka candidatus enterenecus faecium)
O: enterococcus hirae
P: None of the above. | [A; M; F] |
<Instruct>: Given the context 'The group D enterococci include three main species S. faecalis, S. faecium, and S. durans.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecalis; s. faecium; s. durans]
<Options>: A: streptococcus anginosus subsp. anginosus
B: brachybacterium faecium
C: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
D: 'staphylococcus faecalis' (aka staphylococcus faecalis)
E: enterococcus proteiformis (aka enterococcus faecalis)
F: streptococcus faecium (aka enterococcus faecium)
G: streptococcus fermentans
H: corynebacterium faecium
I: streptococcus infantis
J: streptococcus equisimilis (aka streptococcus dysgalactiae subsp. equisimilis)
K: bacteroides faecium
L: streptococcus durans (aka enterococcus durans)
M: escherichia faecalis ('escherichia faecalis') (aka escherichia faecalis)
N: enterococcus coli (aka escherichia coli)
O: enterococcus plantarum
P: None of the above. | [E; F; L] |
<Instruct>: Given the context 'S. faecium cause a minority of all cases of enterococcal endocarditis, in those instances in which enterococci have been speciated [3], but they have been more resistant both to penicillin and penicillin-aminoglycoside combinations than S. faecalis [4,5,6].
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; s. faecalis]
<Options>: A: enterococcus faecalis (streptococcus glycerinaceus) (aka enterococcus faecalis)
B: enterococcus cecorum (streptococcus cecorum) (aka enterococcus cecorum)
C: enterococcus proteiformis (aka enterococcus faecalis)
D: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
E: clostridium faecium
F: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
G: enterococcus
H: enterenecus faecium (aka candidatus enterenecus faecium)
I: streptococcus mutans
J: None of the above. | [F; A] |
<Instruct>: Given the context 'S. faecium cause a minority of all cases of enterococcal endocarditis, in those instances in which enterococci have been speciated [3], but they have been more resistant both to penicillin and penicillin-aminoglycoside combinations than S. faecalis [4,5,6].
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; s. faecalis]
<Options>: A: enterococcus gallinarum (streptococcus gallinarum) (aka enterococcus gallinarum)
B: enterococcus hirae
C: enterococcus proteiformis (aka enterococcus faecalis)
D: escherichia faecalis ('escherichia faecalis') (aka escherichia faecalis)
E: sphingobacterium faecium
F: bacteroides faecalis
G: streptococcus faecium (aka enterococcus faecium)
H: enterococcus coli (aka escherichia coli)
I: enterococcus florum
J: None of the above. | [G; C] |
<Instruct>: Given the context 'We describe a 64-year-old man with S. faecium endocarditis in whom a six-week course of ampicillin and tobramycin, followed by additional courses of penicillin and other aminoglycosides, failed to eradicate the organism from the patient's mitral valve.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [man; s. faecium; patient]
<Options>: A: enterenecus faecium (aka candidatus enterenecus faecium)
B: this
C: humans (aka homo)
D: clostridium faecium
E: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
F: species
G: suborder
H: mus musculus (house mouse) (aka mus musculus)
I: human (aka homo sapiens)
J: birds (aka aves)
K: streptococcus faecium (aka enterococcus faecium)
L: cancer
M: homo (humans) (aka homo)
N: enterococcus casseliflavus (streptococcus faecium subsp. casseliflavus) (aka enterococcus casseliflavus)
O: None of the above. | [I; K; I] |
<Instruct>: Given the context 'We describe a 64-year-old man with S. faecium endocarditis in whom a six-week course of ampicillin and tobramycin, followed by additional courses of penicillin and other aminoglycosides, failed to eradicate the organism from the patient's mitral valve.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [man; s. faecium; patient]
<Options>: A: macrobiotus sapiens
B: probles
C: 'staphylococcus faecalis' (aka staphylococcus faecalis)
D: streptococcus faecium (aka enterococcus faecium)
E: mus <subgenus> (mus (aka mus <subgenus>))
F: enterococcus florum
G: bacteroides faecium
H: mammals (aka mammalia)
I: enterococcus
J: this
K: human (aka homo sapiens)
L: genus
M: suborder
N: data
O: None of the above. | [K; D; K] |
<Instruct>: Given the context 'We describe a 64-year-old man with S. faecium endocarditis in whom a six-week course of ampicillin and tobramycin, followed by additional courses of penicillin and other aminoglycosides, failed to eradicate the organism from the patient's mitral valve.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [man; s. faecium; patient]
<Options>: A: enterococcus faecium e155
B: this
C: streptococcus faecium (aka enterococcus faecium)
D: mammals (aka mammalia)
E: goes
F: circe
G: genus
H: homo sapiens (human) (aka homo sapiens)
I: sphingobacterium faecium
J: other (aka unidentified)
K: brachybacterium faecium
L: subsection
M: neandertal man (aka homo sapiens neanderthalensis)
N: corynebacterium faecium
O: None of the above. | [H; C; H] |
<Instruct>: Given the context 'We describe a 64-year-old man with S. faecium endocarditis in whom a six-week course of ampicillin and tobramycin, followed by additional courses of penicillin and other aminoglycosides, failed to eradicate the organism from the patient's mitral valve.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [man; s. faecium; patient]
<Options>: A: streptococcus faecium (aka enterococcus faecium)
B: enterococcus faecium e155
C: mammals (aka mammalia)
D: sphingobacterium faecium
E: this
F: brachybacterium faecium
G: circe
H: other (aka unidentified)
I: corynebacterium faecium
J: neandertal man (aka homo sapiens neanderthalensis)
K: subsection
L: genus
M: goes
N: None of the above. | [N; A; N] |
<Instruct>: Given the context 'This case is of interest because therapeutic failure of ampicillin and tobramycin in S. faecium endocarditis has not been reported previously, but might have been predicted on the basis of previous in vitro and in vivo studies [6].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: enterococcus florum
B: enterococcus proteiformis (aka enterococcus faecalis)
C: enterococcus faecium e155
D: streptococcus faecium (aka enterococcus faecium)
E: brachybacterium faecium
F: None of the above. | [D] |
<Instruct>: Given the context 'Although the need for both a penicillin derivative and an aminoglycoside in the therapy of enterococcal endocarditis is widely known, it is important to distinguish between the differing efficacies of penicillin-aminoglycoside combinations for treating various species of enterococci such as S. faecium.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: enterococcus florum
B: avispirillum faecium (aka candidatus avispirillum faecium)
C: brachybacterium faecium
D: enterenecus faecium (aka candidatus enterenecus faecium)
E: streptococcus faecium (aka enterococcus faecium)
F: None of the above. | [E] |
<Instruct>: Given the context 'In March 1981, the patient was admitted to his community hospital where evaluation revealed a new apical systolic murmur radiating to the axilla.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: cancer
B: isolate
C: homo sapiens (human) (aka homo sapiens)
D: theraps
E: data
F: None of the above. | [C] |
<Instruct>: Given the context 'Serum bactericidal titers against the organism, obtained during peak antibiotic levels, were 1:8 or greater on several occasions, and blood cultures were negative while the patient was receiving antibiotics.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: theraps
B: data
C: human (aka homo sapiens)
D: subsection
E: other (aka unidentified)
F: None of the above. | [C] |
<Instruct>: Given the context 'Three separate morphologic colony variants were isolated from blood, each identified as S. faecium by Dr. R.R. Facklam (Center for Disease Control, Atlanta, Georgia).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: brachybacterium faecium
B: corynebacterium faecium
C: enterococcus hirae
D: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
E: bacteroides faecium
F: None of the above. | [D] |
<Instruct>: Given the context 'The patient received intravenous penicillin (20 million units per day) and gentamicin (3 mg per kg per day) for six weeks with improvement.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: theraps
B: genus
C: kingdom
D: probles
E: human (aka homo sapiens)
F: None of the above. | [E] |
<Instruct>: Given the context 'Multiple blood cultures taken while the patient was receiving antibiotics were negative, as were those obtained 48 and 72 hours after discontinuation of antibiotics.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: this
B: isolate
C: human (aka homo sapiens)
D: other (aka unidentified)
E: probles
F: None of the above. | [C] |
<Instruct>: Given the context '244
S. FAECIUM ENDOCARDITIS
Third Admission (August 12-October 4, 1981)
Withing a week following discharge, the patient again developed fever, nocturnal sweats, and malaise.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; patient]
<Options>: A: enterenecus faecium (aka candidatus enterenecus faecium)
B: humans (aka homo)
C: streptococcus faecium var. casseliflavus (aka enterococcus casseliflavus)
D: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
E: bacteroides faecium
F: this
G: other (aka unidentified)
H: streptococcus faecium (aka enterococcus faecium)
I: homo sapiens (human) (aka homo sapiens)
J: subsection
K: None of the above. | [H; I] |
<Instruct>: Given the context '244
S. FAECIUM ENDOCARDITIS
Third Admission (August 12-October 4, 1981)
Withing a week following discharge, the patient again developed fever, nocturnal sweats, and malaise.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; patient]
<Options>: A: sphingobacterium faecium
B: mouse (aka mus musculus)
C: enterococcus faecium e155
D: species
E: homo sapiens (human) (aka homo sapiens)
F: streptococcus faecium (aka enterococcus faecium)
G: corynebacterium faecium
H: enterenecus faecium (aka candidatus enterenecus faecium)
I: cancer
J: isolate
K: None of the above. | [F; E] |
<Instruct>: Given the context 'S. faecium (large colony morphotype, and poorly growing small colony morphotype) grew from six sets of blood cultures obtained on admission.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: streptococcus faecalis (aka enterococcus faecalis)
B: clostridium faecium
C: streptococcus faecium (aka enterococcus faecium)
D: enterococcus florum
E: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
F: None of the above. | [C] |
<Instruct>: Given the context 'The patient underwent mitral valve replacement, receiving a number 31 porcine Hancock bioprosthesis and bypass graft to the midportion of the LAD.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: this
B: kingdom
C: homo sapiens (human) (aka homo sapiens)
D: data
E: goes
F: None of the above. | [C] |
<Instruct>: Given the context 'Bacterial and fungal stains were negative but S. faecium grew from fragments of the resected valve.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
B: streptococcus faecium var. casseliflavus (aka enterococcus casseliflavus)
C: enterococcus faecium e155
D: enterenecus faecium (aka candidatus enterenecus faecium)
E: clostridium faecium
F: None of the above. | [A] |
<Instruct>: Given the context 'Following surgery the patient received six additional weeks parenteral penicillin and streptomycin.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: data
B: genus
C: human (aka homo sapiens)
D: cancer
E: this
F: None of the above. | [C] |
<Instruct>: Given the context 'The minimum inhibitory and bactericidal concentrations of penicillin, ampicillin, and tobramycin against the S. faecium isolated from the patient's blood cultures
TABLE 1
Minimum Inhibitory and Bactericidal Concentrations of Antibiotics,
Against Streptococcus faecium Isolates from Blood Cultures
Date Penicillin Ampicillin Tobramycin
Organism Isolated MIC MIC MBC MIC MBC S. faecium, prior to ampicillin/
tobramycin therapy 3/17/81 2 1 2 >32 >32 S. faecium, after ampicillin/
tobramycin therapy
a.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; patient; streptococcus faecium]
<Options>: A: cancer
B: avispirillum faecium (aka candidatus avispirillum faecium)
C: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
D: streptococcus faecium subsp. casseliflavus (aka enterococcus casseliflavus)
E: human (aka homo sapiens)
F: sphingobacterium faecium
G: enterococcus
H: corynebacterium faecium
I: enterenecus faecium (aka candidatus enterenecus faecium)
J: isolate
K: streptococcus faecalis (aka enterococcus faecalis)
L: humans (aka homo)
M: theraps
N: bacteroides faecium
O: None of the above. | [C; E; C] |
<Instruct>: Given the context 'The minimum inhibitory and bactericidal concentrations of penicillin, ampicillin, and tobramycin against the S. faecium isolated from the patient's blood cultures
TABLE 1
Minimum Inhibitory and Bactericidal Concentrations of Antibiotics,
Against Streptococcus faecium Isolates from Blood Cultures
Date Penicillin Ampicillin Tobramycin
Organism Isolated MIC MIC MBC MIC MBC S. faecium, prior to ampicillin/
tobramycin therapy 3/17/81 2 1 2 >32 >32 S. faecium, after ampicillin/
tobramycin therapy
a.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; patient; streptococcus faecium]
<Options>: A: bacteroides faecium
B: enterenecus faecium (aka candidatus enterenecus faecium)
C: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
D: theraps
E: homo sapiens (human) (aka homo sapiens)
F: proxys
G: species
H: clostridium faecium
I: brachybacterium faecium
J: this
K: corynebacterium faecium
L: enterococcus avium (streptococcus avium) (aka enterococcus avium)
M: 'staphylococcus faecalis' (aka staphylococcus faecalis)
N: None of the above. | [C; E; C] |
<Instruct>: Given the context 'The minimum inhibitory and bactericidal concentrations of penicillin, ampicillin, and tobramycin against the S. faecium isolated from the patient's blood cultures
TABLE 1
Minimum Inhibitory and Bactericidal Concentrations of Antibiotics,
Against Streptococcus faecium Isolates from Blood Cultures
Date Penicillin Ampicillin Tobramycin
Organism Isolated MIC MIC MBC MIC MBC S. faecium, prior to ampicillin/
tobramycin therapy 3/17/81 2 1 2 >32 >32 S. faecium, after ampicillin/
tobramycin therapy
a.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; patient; streptococcus faecium]
<Options>: A: clostridium faecium
B: 'staphylococcus faecalis' (aka staphylococcus faecalis)
C: corynebacterium faecium
D: this
E: enterococcus faecium e155
F: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
G: enterococcus plantarum
H: brachybacterium faecium
I: enterococcus hirae
J: circe
K: homo sapiens (human) (aka homo sapiens)
L: enterenecus faecium (aka candidatus enterenecus faecium)
M: proxys
N: goes
O: None of the above. | [F; K; F] |
<Instruct>: Given the context 'The minimum inhibitory and bactericidal concentrations of penicillin, ampicillin, and tobramycin against the S. faecium isolated from the patient's blood cultures
TABLE 1
Minimum Inhibitory and Bactericidal Concentrations of Antibiotics,
Against Streptococcus faecium Isolates from Blood Cultures
Date Penicillin Ampicillin Tobramycin
Organism Isolated MIC MIC MBC MIC MBC S. faecium, prior to ampicillin/
tobramycin therapy 3/17/81 2 1 2 >32 >32 S. faecium, after ampicillin/
tobramycin therapy
a.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: brachybacterium faecium
B: enterococcus faecium e155
C: enterococcus hirae
D: streptococcus faecium (aka enterococcus faecium)
E: corynebacterium faecium
F: None of the above. | [D] |
<Instruct>: Given the context '3- \ "'' ing the effects of various penicillinO aminoglycoside combinations on S. {73 2- \ >, faecium obtained from the patient's
blood cultures immediately prior to mitral valve excision.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: humans (aka homo)
C: isolate
D: aides
E: circe
F: None of the above. | [A] |
<Instruct>: Given the context 'Twenty-four hour time-kill curves for penicillin in combination with various aminoglycosides were performed by Dr. Robert Moellering on the S. faecium isolated from the patient's blood immediately prior to mitral valve excision and replacement (Fig. 1).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; patient]
<Options>: A: bacteroides faecium
B: kingdom
C: enterenecus faecium (aka candidatus enterenecus faecium)
D: enterococcus faecium e155
E: isolate
F: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
G: 'staphylococcus faecalis' (aka staphylococcus faecalis)
H: human (aka homo sapiens)
I: this
J: goes
K: None of the above. | [F; H] |
<Instruct>: Given the context 'Twenty-four hour time-kill curves for penicillin in combination with various aminoglycosides were performed by Dr. Robert Moellering on the S. faecium isolated from the patient's blood immediately prior to mitral valve excision and replacement (Fig. 1).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; patient]
<Options>: A: this
B: enterococcus faecium e155
C: streptococcus faecium (aka enterococcus faecium)
D: brachybacterium faecium
E: species
F: homo sapiens (human) (aka homo sapiens)
G: proxys
H: sphingobacterium faecium
I: enterococcus hirae
J: circe
K: None of the above. | [C; F] |
<Instruct>: Given the context 'Twenty-four hour time-kill curves for penicillin in combination with various aminoglycosides were performed by Dr. Robert Moellering on the S. faecium isolated from the patient's blood immediately prior to mitral valve excision and replacement (Fig. 1).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; patient]
<Options>: A: this
B: streptococcus faecium (aka enterococcus faecium)
C: enterococcus faecium e155
D: species
E: proxys
F: brachybacterium faecium
G: sphingobacterium faecium
H: circe
I: enterococcus hirae
J: None of the above. | [B; J] |
<Instruct>: Given the context 'Although S. faecalis represents the majority of clinical enterococcal isolates, S. faecium nonetheless comprises 5-10 percent of these isolates in some series [3,4].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecalis; s. faecium]
<Options>: A: enterococcus
B: bacteroides faecalis
C: bacteroides faecium
D: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
E: brachybacterium faecium
F: streptococcus faecium (aka enterococcus faecium)
G: 'escherichia faecalis' (aka escherichia faecalis)
H: 'staphylococcus faecalis' (aka staphylococcus faecalis)
I: enterococcus faecalis (streptococcus glycerinaceus) (aka enterococcus faecalis)
J: enterococcus florum
K: None of the above. | [I; F] |
<Instruct>: Given the context 'Although S. faecalis represents the majority of clinical enterococcal isolates, S. faecium nonetheless comprises 5-10 percent of these isolates in some series [3,4].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecalis; s. faecium]
<Options>: A: streptococcus faecium (aka enterococcus faecium)
B: sphingobacterium faecium
C: enterococcus proteiformis (aka enterococcus faecalis)
D: bacteroides faecalis
E: enterococcus
F: avispirillum faecium (aka candidatus avispirillum faecium)
G: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
H: streptococcus faecalis (aka enterococcus faecalis)
I: streptococcus cecorum (aka enterococcus cecorum)
J: None of the above. | [C; A] |
<Instruct>: Given the context 'The MIC of penicillin against S. faecium is higher and this organism is more resistant to a number of different combinations of penicillin and various aminoglycosides than is S. faecalis', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; s. faecalis]
<Options>: A: streptococcus cecorum (aka enterococcus cecorum)
B: corynebacterium faecium
C: streptococcus faecalis (aka enterococcus faecalis)
D: avispirillum faecium (aka candidatus avispirillum faecium)
E: enterococcus faecium e155
F: 'escherichia faecalis' (aka escherichia faecalis)
G: bacteroides faecium
H: bacteroides faecalis
I: streptococcus faecium (aka enterococcus faecium)
J: None of the above. | [I; C] |
<Instruct>: Given the context 'The MIC of penicillin against S. faecium is higher and this organism is more resistant to a number of different combinations of penicillin and various aminoglycosides than is S. faecalis', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; s. faecalis]
<Options>: A: streptococcus faecium (aka enterococcus faecium)
B: enterenecus faecium (aka candidatus enterenecus faecium)
C: enterococcus florum
D: enterococcus
E: enterococcus plantarum
F: 'escherichia faecalis' (aka escherichia faecalis)
G: enterocoque (aka enterococcus faecalis)
H: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
I: enterococcus proteiformis (aka enterococcus faecalis)
J: enterococcus coli (aka escherichia coli)
K: None of the above. | [A; G] |
<Instruct>: Given the context 'Clinically achievable levels of amino
246
S. FAECIUM ENDOCARDITIS
glycosides are generally ineffective against enterococci.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
B: enterococcus faecium e155
C: avispirillum faecium (aka candidatus avispirillum faecium)
D: enterococcus casseliflavus (streptococcus faecium subsp. casseliflavus) (aka enterococcus casseliflavus)
E: sphingobacterium faecium
F: None of the above. | [A] |
<Instruct>: Given the context 'Plasmid-mediated modifying enzymes have been found in both S. faecalis and S. faecium' [12].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecalis; s. faecium]
<Options>: A: corynebacterium faecium
B: enterococcus proteiformis (aka enterococcus faecalis)
C: enterococcus hirae
D: bacteroides faecalis
E: enterococcus plantarum
F: 'staphylococcus faecalis' (aka staphylococcus faecalis)
G: streptococcus faecium (aka enterococcus faecium)
H: brachybacterium faecium
I: 'escherichia faecalis' (aka escherichia faecalis)
J: enterococcus coli (aka escherichia coli)
K: None of the above. | [B; G] |
<Instruct>: Given the context 'Plasmid-mediated modifying enzymes have been found in both S. faecalis and S. faecium' [12].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecalis; s. faecium]
<Options>: A: streptococcus gallinarum (aka enterococcus gallinarum)
B: enterococcus hirae
C: clostridium faecium
D: enterococcus florum
E: streptococcus faecium (aka enterococcus faecium)
F: streptococcus liquefaciens (aka enterococcus faecalis)
G: enterococcus
H: 'escherichia faecalis' (aka escherichia faecalis)
I: sphingobacterium faecium
J: streptococcus cecorum (aka enterococcus cecorum)
K: None of the above. | [F; E] |
<Instruct>: Given the context 'Combinations of penicillin with kanamycin, tobramycin, sisomicin, and netilmicin have consistently failed to demonstrate synergistic killing of S. faecium in vitro [6].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: enterenecus faecium (aka candidatus enterenecus faecium)
B: clostridium faecium
C: enterococcus hirae
D: streptococcus faecium (aka enterococcus faecium)
E: sphingobacterium faecium
F: None of the above. | [D] |
<Instruct>: Given the context 'Moellering et al. demonstrated in vivo, utilizing the rabbit model of endocarditis, that penicillin and netilmicin were not efficacious in the treatment of endocarditis caused by a low-level aminoglycoside-resistant strain of S. faecium [6].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit; s. faecium]
<Options>: A: streptococcus faecium (aka enterococcus faecium)
B: lepus (hares) (aka lepus)
C: domestic rabbit (aka oryctolagus cuniculus)
D: enterenecus faecium (aka candidatus enterenecus faecium)
E: lepus cuniculus cuniculus (aka oryctolagus cuniculus cuniculus)
F: corynebacterium faecium
G: streptococcus faecium subsp. casseliflavus (aka enterococcus casseliflavus)
H: sphingobacterium faecium
I: european hare (aka lepus europaeus)
J: bovidae
K: None of the above. | [C; A] |
<Instruct>: Given the context 'Moellering et al. demonstrated in vivo, utilizing the rabbit model of endocarditis, that penicillin and netilmicin were not efficacious in the treatment of endocarditis caused by a low-level aminoglycoside-resistant strain of S. faecium [6].', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [rabbit; s. faecium]
<Options>: A: bovidae
B: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
C: lepus cuniculus cuniculus (aka oryctolagus cuniculus cuniculus)
D: enterococcus proteiformis (aka enterococcus faecalis)
E: domestic rabbit (aka oryctolagus cuniculus)
F: lepus europaeus europaeus
G: brachybacterium faecium
H: ox (aka bos taurus) (aka bos taurus)
I: avispirillum faecium (aka candidatus avispirillum faecium)
J: enterococcus hirae
K: None of the above. | [E; B] |
<Instruct>: Given the context 'In the present case, the recurrence of S. faecium endocarditis after six weeks of therapy with ampicillin and tobramycin confirms the therapeutic and clinical significance of their data, and emphasizes that tobramycin is not an aminoglycoside to be used for treatment of serious S. faecium infections.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: brachybacterium faecium
B: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
C: enterococcus florum
D: corynebacterium faecium
E: clostridium faecium
F: None of the above. | [B] |
<Instruct>: Given the context 'Bacterial tolerance has been suggested as a possible basis for therapeutic failures, particularly in the treatment of infections caused by Staphylococcus aureus with defects in the production of autolysins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [staphylococcus aureus]
<Options>: A: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
B: staphylococcus group (aka staphylococcaceae)
C: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus)
D: staphylococcus sp. s
E: staphylococcus aureus str. pa (aka staphylococcus aureus pa)
F: None of the above. | [C] |
<Instruct>: Given the context 'Bacterial tolerance has been suggested as a possible basis for therapeutic failures, particularly in the treatment of infections caused by Staphylococcus aureus with defects in the production of autolysins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [staphylococcus aureus]
<Options>: A: staphylococcus aureus subsp. aureus col (staphylococcus aureus col) (aka staphylococcus aureus subsp. aureus col)
B: staphylococcus aureus str. pa (aka staphylococcus aureus pa)
C: staphylococcus group (aka staphylococcaceae)
D: staphylococcus sp. s
E: None of the above. | [E] |
<Instruct>: Given the context 'Lorian has also described the formation of numerous aberrant cross-walls by S. faecalis grown in the presence of subinhibitory concentrations of penicillin', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecalis]
<Options>: A: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
B: enterococcus cecorum (streptococcus cecorum) (aka enterococcus cecorum)
C: enterococcus plantarum
D: enterococcus faecalis (streptococcus glycerinaceus) (aka enterococcus faecalis)
E: streptococcus mutans
F: None of the above. | [D] |
<Instruct>: Given the context 'MBCs were only slightly higher than MICs for the three S. faecium variants obtained from our patient, and they did not appear to be tolerant strains of S. faecium.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; patient]
<Options>: A: enterococcus proteiformis (aka enterococcus faecalis)
B: bacteroides faecium
C: human (aka homo sapiens)
D: humans (aka homo)
E: corynebacterium faecium
F: streptococcus faecium (aka enterococcus faecium)
G: this
H: streptococcus faecium subsp. casseliflavus (aka enterococcus casseliflavus)
I: theraps
J: proxys
K: None of the above. | [F; C] |
<Instruct>: Given the context 'MBCs were only slightly higher than MICs for the three S. faecium variants obtained from our patient, and they did not appear to be tolerant strains of S. faecium.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium; patient]
<Options>: A: bacteroides faecium
B: circe
C: 'staphylococcus faecalis' (aka staphylococcus faecalis)
D: this
E: enterococcus florum
F: kingdom
G: theraps
H: human (aka homo sapiens)
I: streptococcus faecium (aka enterococcus faecium)
J: enterococcus
K: None of the above. | [I; H] |
<Instruct>: Given the context 'Alternatively, a
'Wennersten C, Moellering RC Jr: Mechanism of resistance to penicillin-aminoglycoside synergism in Streptococcus faecium.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [streptococcus faecium]
<Options>: A: enterenecus faecium (aka candidatus enterenecus faecium)
B: enterococcus faecalis (streptococcus glycerinaceus) (aka enterococcus faecalis)
C: corynebacterium faecium
D: bacteroides faecium
E: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
F: None of the above. | [E] |
<Instruct>: Given the context 'In summary, our patient was treated for Streptococcusfaecium endocarditis with both ampicillin and the aminoglycoside antibiotic, tobramycin.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; streptococcusfaecium]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: circe
C: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
D: streptococcus faecalis (aka enterococcus faecalis)
E: streptococcus faecavium (aka candidatus streptococcus faecavium)
F: kingdom
G: clostridium faecium
H: suborder
I: streptococcus ferus
J: goes
K: None of the above. | [A; C] |
<Instruct>: Given the context 'In summary, our patient was treated for Streptococcusfaecium endocarditis with both ampicillin and the aminoglycoside antibiotic, tobramycin.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; streptococcusfaecium]
<Options>: A: humans (aka homo)
B: enterococcus plantarum
C: enterococcus florum
D: homo sapiens (human) (aka homo sapiens)
E: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
F: enterococcus cecorum (streptococcus cecorum) (aka enterococcus cecorum)
G: data
H: mouse (aka mus musculus)
I: aides
J: sphingobacterium faecium
K: None of the above. | [D; E] |
<Instruct>: Given the context 'In summary, our patient was treated for Streptococcusfaecium endocarditis with both ampicillin and the aminoglycoside antibiotic, tobramycin.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient; streptococcusfaecium]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: data
C: humans (aka homo)
D: enterococcus florum
E: enterococcus plantarum
F: sphingobacterium faecium
G: aides
H: enterococcus cecorum (streptococcus cecorum) (aka enterococcus cecorum)
I: mouse (aka mus musculus)
J: None of the above. | [A; J] |
<Instruct>: Given the context 'The authors also wish to thank Dr. Howard S. Forster for referring this patient to us, Ms. Mary Murray and Deborah Beauvais for manuscript preparation, and Ms. Gertrude Barden, MT (ASCP), MHS, for technical assistance and advice in evaluation of this patient.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [patient]
<Options>: A: isolate
B: human (aka homo sapiens)
C: aides
D: cancer
E: theraps
F: None of the above. | [B] |
<Instruct>: Given the context 'Facklam RR: Recognition of group D streptococcal species of human origin by biochemical and
physiological tests.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [human]
<Options>: A: homo sapiens (human) (aka homo sapiens)
B: biota (aka cellular organisms)
C: macrobiotus sapiens
D: animals (aka metazoa)
E: homo (humans) (aka homo)
F: None of the above. | [A] |
<Instruct>: Given the context 'Shungu DL, Cornett JB, Shockman GD: Morphological and physiological study of autolytic
defective Streptococcus faecium strains.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [streptococcus faecium]
<Options>: A: enterenecus faecium (aka candidatus enterenecus faecium)
B: brachybacterium faecium
C: bacteroides faecium
D: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
E: sphingobacterium faecium
F: None of the above. | [D] |
<Instruct>: Given the context 'Moellering RC Jr, Korzeniowski OM, Sande MA, et al: Species-specific resistance to antimicrobial
synergism in Streptococcusfaecium and Streptococcusfaecalis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [streptococcusfaecium; streptococcusfaecalis]
<Options>: A: enterococcus faecalis (streptococcus glycerinaceus) (aka enterococcus faecalis)
B: bacteroides faecalis
C: 'staphylococcus faecalis' (aka staphylococcus faecalis)
D: streptococcus gallinaceus
E: enterococcus cecorum (streptococcus cecorum) (aka enterococcus cecorum)
F: streptococcus cecorum (aka enterococcus cecorum)
G: streptococcus faecium (aka enterococcus faecium)
H: enterococcus florum
I: None of the above. | [G; A] |
<Instruct>: Given the context 'Moellering RC Jr, Korzeniowski OM, Sande MA, et al: Species-specific resistance to antimicrobial
synergism in Streptococcusfaecium and Streptococcusfaecalis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [streptococcusfaecium; streptococcusfaecalis]
<Options>: A: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
B: sphingobacterium faecium
C: bacteroides faecalis
D: streptococcus faecalis (aka enterococcus faecalis)
E: streptococcus intestinalis (aka streptococcus alactolyticus)
F: streptococcus faecium (aka enterococcus faecium)
G: streptococcus penaeicida
H: 'staphylococcus faecalis' (aka staphylococcus faecalis)
I: streptococcus ferus
J: None of the above. | [F; D] |
<Instruct>: Given the context 'Moellering RC Jr, Murray BE, Schoenbaum SC, et al: A novel mechanism of resistance to penicillin
gentamicin synergism in S. faecalis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecalis]
<Options>: A: streptococcus faecium (aka enterococcus faecium)
B: enterococcus gallinarum (streptococcus gallinarum) (aka enterococcus gallinarum)
C: enterococcus plantarum
D: streptococcus faecalis (aka enterococcus faecalis)
E: enterococcus cecorum (streptococcus cecorum) (aka enterococcus cecorum)
F: None of the above. | [D] |
<Instruct>: Given the context 'Krogstad DJ, Korfhagen TR, Moellering RC Jr, et al: Aminoglycoside-inactivating enzymes in
clinical isolates of Streptococcusfaecalis: An explanation for resistance to antibiotic synergism.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [streptococcusfaecalis]
<Options>: A: streptococcus gallinaceus
B: enterococcus faecalis (streptococcus glycerinaceus) (aka enterococcus faecalis)
C: streptococcus faecavium (aka candidatus streptococcus faecavium)
D: streptococcus ferus
E: streptococcus ovis
F: None of the above. | [B] |
<Instruct>: Given the context 'J Clin Invest 62:480-486, 1978
S. FAECIUM ENDOCARDITIS 249
12.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: enterococcus florum
B: enterenecus faecium (aka candidatus enterenecus faecium)
C: bacteroides faecium
D: streptococcus faecium (aka enterococcus faecium)
E: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
F: None of the above. | [D] |
<Instruct>: Given the context 'J Clin Invest 62:480-486, 1978
S. FAECIUM ENDOCARDITIS 249
12.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [s. faecium]
<Options>: A: enterenecus faecium (aka candidatus enterenecus faecium)
B: bacteroides faecium
C: enterococcus florum
D: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
E: None of the above. | [E] |
<Instruct>: Given the context 'Abstract
A recombinant phage, SpC3, containing a 17 kb genomic DNA insert representing approximately 60% of the 3' portion of the sheep collagen alpha 2 gene, was evaluated by electron microscopic R loop analysis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis aries vignei (aka ovis vignei)
B: sheep (aka ovis aries)
C: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
D: dall's sheep (aka ovis dalli)
E: cow (aka bos taurus) (aka bos taurus)
F: None of the above. | [B] |
<Instruct>: Given the context 'Images
Nucleic Acids Research
Structural organization of a 17 KB segment of the a2 collagen gene: evaluation by R loop mapping Millie P.Schafer, Charles D.Boyd, Paul Tolstoshev and Ronald G.Crystal
Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20205, USA
Received 13 February 1980
ABSTRACT
A recombinant phage, SpC3, containing a 17 kb genomic DNA insert rep
resenting approximately 60% of the 3' portion of the sheep collagen a2 gene, was evaluated by electron microscopic R loop analysis.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis
B: domestic sheep (aka ovis aries)
C: suidae (pigs (aka suidae))
D: cow (aka bos taurus) (aka bos taurus)
E: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
F: None of the above. | [B] |
<Instruct>: Given the context 'The present study further characterizes this portion of the a2
gene by utilizing electron microscopic R loop analysis to map the coding regions (exons) and intervening sequences (introns) contained within the sheep genomic insert of SpC3.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
B: sheep (aka ovis aries)
C: ovis sp.
D: cattle (aka bos)
E: cow (aka bos taurus) (aka bos taurus)
F: None of the above. | [B] |
<Instruct>: Given the context 'The sheep a2 collagen recombinant clone, SpC3, containing a portion of the sheep a2 gene, was isolated as previously described (2).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis dalli (dall's sheep) (aka ovis dalli)
B: suidae (pigs (aka suidae))
C: bovidae
D: ovis aries vignei (aka ovis vignei)
E: wild sheep (aka ovis aries)
F: None of the above. | [E] |
<Instruct>: Given the context 'Briefly,
high molecular weight fetal sheep liver DNA was extracted by the method of Blin and Stafford (3), and 15-20 kb DNA fragments, resulting from partial Eco RI digestion, were isolated and ligated to the left and right arms of Charon 4A.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis
B: cattle (aka bos)
C: bovidae
D: ovis sp.
E: ovis ovis (aka ovis aries)
F: None of the above. | [E] |
<Instruct>: Given the context 'The recombinant DNA was then packaged in vitro and the sheep
genomic library amplified (4-6).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: cow (aka bos taurus) (aka bos taurus)
B: ovis
C: suidae (pigs (aka suidae))
D: lambs (aka ovis aries)
E: cattle (aka bos)
F: None of the above. | [D] |
<Instruct>: Given the context 'Screening of the sheep genomic library was
conducted utilizing [32 P]-labeled fetal sheep tendon type I collagen cDNA and
several positive recombinant phages were isolated.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis ovis (aka ovis aries)
B: ovis
C: cattle (aka bos)
D: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
E: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
F: None of the above. | [A] |
<Instruct>: Given the context 'One recombinant, containing a 17 kb sheep genomic insert, was demonstrated to have coding sequences corresponding to 60% of the 3' end of a2 mRNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
B: cow (aka bos taurus) (aka bos taurus)
C: ovis
D: dall sheep (aka ovis dalli)
E: ovis orientalis aries (aka ovis aries)
F: None of the above. | [E] |
<Instruct>: Given the context 'The construction and screening of the sheep genomic library together with amplification of pCg45 and preparation of high titre lysates of chimaeric
Charon 4A were performed under the physical and biological containment levels specified by the NIH guidelines for recombinant DNA research (11).
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis aries vignei (aka ovis vignei)
B: ovis sp.
C: ovis
D: dall's sheep (aka ovis dalli)
E: sheep (aka ovis aries)
F: None of the above. | [E] |
<Instruct>: Given the context 'Hybridization of fetal sheep tendon type I collagen mRNA to SpC3 DNA
yielded a complex R loop pattern in the region where the sheep genomic insert was expected to be ligated to the arms of the lambda vector, Charon 4A.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis ovis (aka ovis aries)
B: ovis sp.
C: ovis
D: ovis dalli (dall's sheep) (aka ovis dalli)
E: bovidae
F: None of the above. | [A] |
<Instruct>: Given the context 'Hybridization of fetal sheep tendon type I collagen mRNA to SpC3 DNA
yielded a complex R loop pattern in the region where the sheep genomic insert was expected to be ligated to the arms of the lambda vector, Charon 4A.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: bovidae
B: ovis dalli (dall's sheep) (aka ovis dalli)
C: ovis sp.
D: ovis
E: None of the above. | [E] |
<Instruct>: Given the context 'To
confirm that these hybridization events were restricted to the inserted sheep DNA fragment, duplex DNA strands on both sides of this hybridization area were measured.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis aries (ovis orientalis aries) (aka ovis aries)
B: cattle (aka bos)
C: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
D: ovis aries vignei (aka ovis vignei)
E: dall's sheep (aka ovis dalli)
F: None of the above. | [A] |
<Instruct>: Given the context 'Although, by convention, introns are usually sequentially labeled 5' to 3', an opposite order had to be employed in this case as SpC3 does not contain the sequences coding for the 5' end of sheep a2 mRNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis sp.
B: cow (aka bos taurus) (aka bos taurus)
C: ovis ovis (aka ovis aries)
D: suidae (pigs (aka suidae))
E: dall's sheep (aka ovis dalli)
F: None of the above. | [C] |
<Instruct>: Given the context 'A small non-hybridized tail was consistently found in the region where
the right arm of the phage was ligated to the sheep genomic insert (Figure 1).', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis ammon aries (aka ovis aries)
B: ovis sp.
C: ovis dalli (dall's sheep) (aka ovis dalli)
D: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
E: cow (aka bos taurus) (aka bos taurus)
F: None of the above. | [A] |
<Instruct>: Given the context 'Electron microscopic visualization of all 17 introns and 18 exons
from hybrid molecules formed between recombinant clone SpC3 DNA and fetal sheep
tendon a2 mRNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: bovidae
B: dall's sheep (aka ovis dalli)
C: ovis
D: wild sheep (aka ovis aries)
E: ovis aries vignei (aka ovis vignei)
F: None of the above. | [D] |
<Instruct>: Given the context 'Electron microscopic R loop analysis
present in SpC3 DNA1.
of the sheep a2 introns
SpC3 was hybridized to sheep a2 mRNA as described in Materials and Methods; intron lengths were determined by comparison with *X-174 DNA lengths.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis aries (ovis orientalis aries) (aka ovis aries)
B: cow (aka bos taurus) (aka bos taurus)
C: ovis dalli (dall's sheep) (aka ovis dalli)
D: ovis sp.
E: bovidae
F: None of the above. | [A] |
<Instruct>: Given the context 'Electron microscopic R loop analysis of the sheep a2 exons
present in SpC3 DNA1.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: dall's sheep (aka ovis dalli)
B: bovidae
C: ovis aries vignei (aka ovis vignei)
D: sheep (aka ovis aries)
E: ovis
F: None of the above. | [D] |
<Instruct>: Given the context '36 q5 - _ 33 130?47 r5 r 6 78?36
SpC3 was hybridized to sheep a2 mRNA as described in M4aterials and
Methods; exon lengths were determined by comparison with pBR322 DNA lengths.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: bovidae
B: suidae (pigs (aka suidae))
C: lambs (aka ovis aries)
D: cattle (aka bos)
E: ovis
F: None of the above. | [C] |
<Instruct>: Given the context 'The largest exon, "a", located on the extreme 3' end of the sheep genomic insert, contained
approximately 800 bp.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis
B: suidae (pigs (aka suidae))
C: cow (aka bos taurus) (aka bos taurus)
D: cattle (aka bos)
E: sheep (aka ovis aries)
F: None of the above. | [E] |
<Instruct>: Given the context 'Exon "a" and exon "b", the two exons situated on either side of intron 1, coded for around 1000 bases of a2 collagen information; these two
exons contained one-third of the mapped 3,014 DNA bases complementary to a2 mRNA Length distribution and organization of the introns and exons in the sheep genomi c i nsert.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: cow (aka bos taurus) (aka bos taurus)
B: cattle (aka bos)
C: ovis dalli (dall's sheep) (aka ovis dalli)
D: ovis aries (ovis orientalis aries) (aka ovis aries)
E: suidae (pigs (aka suidae))
F: None of the above. | [D] |
<Instruct>: Given the context 'Therefore, only 18% of the mapped 17 kb sheep genetic insert actually contained a2 structural information.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis
B: cow (aka bos taurus) (aka bos taurus)
C: ovis orientalis aries (aka ovis aries)
D: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
E: suidae (pigs (aka suidae))
F: None of the above. | [C] |
<Instruct>: Given the context 'Therefore, only 18% of the mapped 17 kb sheep genetic insert actually contained a2 structural information.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
B: cow (aka bos taurus) (aka bos taurus)
C: ovis
D: suidae (pigs (aka suidae))
E: None of the above. | [E] |
<Instruct>: Given the context 'A minimum of 17 introns interrupt the 3 kb of ca2 genetic information interspersed as 18 exons over 17 kb of sheep DNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: cow (aka bos taurus) (aka bos taurus)
B: bovidae
C: suidae (pigs (aka suidae))
D: domestic sheep (aka ovis aries)
E: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
F: None of the above. | [D] |
<Instruct>: Given the context 'Although the total number of introns present within the 60% 3' portion
of the a2 sheep gene was determined to be 17, variation in the precise number
TRANSRIPTlO
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: cattle (aka bos)
B: dall's sheep (aka ovis dalli)
C: bovidae
D: suidae (pigs (aka suidae))
E: domestic sheep (aka ovis aries)
F: None of the above. | [E] |
<Instruct>: Given the context '5.5 50 4.5 4.0 3.5 3.0 2.5 2.0 1.5 1.0
KILOBASE
Fiue3 Organization of 60% of the 3' end of the sheep a2 collagen gene.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis sp.
B: ovis
C: ovis aries vignei (aka ovis vignei)
D: sheep (aka ovis aries)
E: cow (aka bos taurus) (aka bos taurus)
F: None of the above. | [D] |
<Instruct>: Given the context 'Very small introns have been reported for tRNA genes (12,13),
and it will be necessary to sequence these regions of SpC3 to determine if such introns are present within the a2 sheep genome.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis sp.
B: ovis ovis (aka ovis aries)
C: ovis
D: bovidae
E: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
F: None of the above. | [B] |
<Instruct>: Given the context 'The existence of mRNAs comprised of sequences complementary to noncontiguous regions in a DNA genome was first described for adenovirus (14,15) and
simian virus (16,17) genes.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [adenovirus]
<Options>: A: duck adenovirus
B: adenoviridae
C: adeno-associated virus clade a
D: adeno-associated virus
E: rodent adenovirus
F: None of the above. | [B] |
<Instruct>: Given the context 'The consistent appearance of a small non-hybridized tail, approximately 100 nucleotides in length, in the region where the right arm of the phage was ligated to the sheep genomic insert of SpC3 very likely corresponded to the
3' poly A sequence of the a2 mRNA.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [sheep]
<Options>: A: ovis
B: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
C: ovis ovis (aka ovis aries)
D: ovis aries vignei (aka ovis vignei)
E: bovidae
F: None of the above. | [C] |
<Instruct>: Given the context 'We are also grateful to Margery Sullivan, Laboratory of Molecular Genetics,
National Institute of Child Health and Human Development, for helpful discussions and to Dr. Helga Boedtker, Department of Chemistry, Harvard University, for making available the recombinant plasmid pCg45.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [child; human]
<Options>: A: this
B: circe
C: mammals (aka mammalia)
D: genus
E: species
F: human (aka homo sapiens)
G: macrobiotus sapiens
H: proeces
I: kingdom
J: None of the above. | [F; F] |
<Instruct>: Given the context 'We are also grateful to Margery Sullivan, Laboratory of Molecular Genetics,
National Institute of Child Health and Human Development, for helpful discussions and to Dr. Helga Boedtker, Department of Chemistry, Harvard University, for making available the recombinant plasmid pCg45.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [child; human]
<Options>: A: menetus
B: macrobiotus sapiens
C: homo sapiens (human) (aka homo sapiens)
D: suborder
E: probles
F: primate (aka primates)
G: avian (aka aves)
H: family
I: genus
J: None of the above. | [C; C] |
<Instruct>: Given the context 'We are also grateful to Margery Sullivan, Laboratory of Molecular Genetics,
National Institute of Child Health and Human Development, for helpful discussions and to Dr. Helga Boedtker, Department of Chemistry, Harvard University, for making available the recombinant plasmid pCg45.
', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [child; human]
<Options>: A: probles
B: genus
C: family
D: primate (aka primates)
E: suborder
F: menetus
G: avian (aka aves)
H: macrobiotus sapiens
I: None of the above. | [I; I] |
<Instruct>: Given the context 'Scp160p, a multiple KH-domain protein, is a component of mRNP complexes in yeast
Abstract
Scp160p is a 160 kDa protein in the yeast Saccharomyces cerevisiae that contains 14 repeats of the hnRNP K-homology (KH) domain, and demonstrates significant sequence homology to a family of proteins collectively known as vigilins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yeast; saccharomyces cerevisiae]
<Options>: A: budding yeasts & others (aka saccharomycotina)
B: saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (aka saccharomyces cerevisiae)
C: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
D: saccharomyces cerevisiae x saccharomyces mikatae
E: saccharomyces hansenii (aka debaryomyces hansenii)
F: saccharomyces sp.
G: saccharomyceta
H: saccharomyces cerevisiae synthetic construct
I: None of the above. | [B; B] |
<Instruct>: Given the context 'Scp160p, a multiple KH-domain protein, is a component of mRNP complexes in yeast
Abstract
Scp160p is a 160 kDa protein in the yeast Saccharomyces cerevisiae that contains 14 repeats of the hnRNP K-homology (KH) domain, and demonstrates significant sequence homology to a family of proteins collectively known as vigilins.', select the correct biomedical concept for each mention using the provided options. Answer by listing the selected options, one for each mention, separated by semicolon. | <Mentions>: [yeast; saccharomyces cerevisiae]
<Options>: A: saccharomyces cerevisiae x saccharomyces mikatae
B: mycoderma cerevisiae (aka saccharomyces cerevisiae)
C: saccharomyces cerevisiae x saccharomyces paradoxus
D: saccharomyces sp.
E: saccharomyces albicans (aka candida albicans)
F: saccharomycodes
G: saccharomyces lactis (aka kluyveromyces lactis)
H: saccharomyces hansenii (aka debaryomyces hansenii)
I: None of the above. | [B; B] |
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