instruction stringlengths 161 2.29k | input stringlengths 80 650 | response stringclasses 6 values |
|---|---|---|
<Instruct>: Given the context 'Muc1 knockout mice (Muc1-/-; MUC1 is human; Muc1 is mouse)', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: macrobiotus sapiens
B: animals (aka metazoa)
C: species
D: human (aka homo sapiens)
E: cellular organisms (biota) (aka cellular organisms)
F: None of the above. | D |
<Instruct>: Given the context 'Muc1 knockout mice (Muc1-/-; MUC1 is human; Muc1 is mouse)', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: avian (aka aves)
B: probles
C: cellular organisms (biota) (aka cellular organisms)
D: humans (aka homo)
E: kingdom
F: None of the above. | F |
<Instruct>: Given the context 'Muc1 knockout mice (Muc1-/-; MUC1 is human; Muc1 is mouse)', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus sp. (mice (aka mus sp.))
B: mouse (aka mus musculus)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mus <genus> (mice (aka mus <genus>))
F: None of the above. | B |
<Instruct>: Given the context 'show a reduction in tumorigenic phenotype when crossed onto mice overexpressing the Wnt-1', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mouse (aka mus <genus>)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mouse (aka mus musculus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | D |
<Instruct>: Given the context 'Materials and methods
Cell culture and siRNA transfection
MDA-MB-468 and BT-20 cells (American Type Culture Collection) were cultured in Dulbecco's modified Eagle's medium (Invitrogen, Carlsbad, CA, USA) plus 10% fetal calf serum, 1% Glutamax (Invitrogen) and 1% penicillin/streptomycin.', select the correct biomedical concept corresponding to 'calf'. Answer using one of the provided options. | <Options>: A: equine (aka equus caballus)
B: bovine (aka bos taurus)
C: equetus
D: bos (cattle) (aka bos)
E: sueus
F: None of the above. | B |
<Instruct>: Given the context 'Non-commercial antibodies used were: BC2, a mouse monoclonal to the MUC1-EX (gift of Dr McGuckin, Queensland University, Queensland, Australia), and CT2, an Armenian hamster monoclonal to the MUC1-CT developed in our lab', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mouse (aka mus musculus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mouse (aka mus <genus>)
D: mus domesticus (aka mus musculus domesticus)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | A |
<Instruct>: Given the context 'Non-commercial antibodies used were: BC2, a mouse monoclonal to the MUC1-EX (gift of Dr McGuckin, Queensland University, Queensland, Australia), and CT2, an Armenian hamster monoclonal to the MUC1-CT developed in our lab', select the correct biomedical concept corresponding to 'armenian hamster'. Answer using one of the provided options. | <Options>: A: romanian hamster (aka mesocricetus newtoni)
B: djungarian hamster (aka phodopus campbelli)
C: chinese hamster (aka cricetulus griseus)
D: cricetus cricetus (black-bellied hamster) (aka cricetus cricetus)
E: grey hamster (aka nothocricetulus migratorius)
F: None of the above. | E |
<Instruct>: Given the context 'Following washing and 2 minute's incubation with 0.1 M Tris to neutralize the acid, cells were re-suspended in FACS buffer (0.5% fetal calf serum in PBS) and stained with Phycoerythrin (PE)-conjugated anti-BrdU according to the manufacturer's protocol for flow cytometry analysis on a FACScan instrument.
', select the correct biomedical concept corresponding to 'calf'. Answer using one of the provided options. | <Options>: A: domestic cow (aka bos taurus)
B: equetus
C: sueus
D: mus spretus (mus musculus spretus) (aka mus spretus)
E: equidae (horses) (aka equidae)
F: None of the above. | A |
<Instruct>: Given the context 'Two human breast cancer cell lines, MDA-MB-468 and BT-20, were transiently transfected with a pool of four siRNA oligonucleotides directed against the MUC1 mRNA (468.siMUC1 and BT.siMUC1), or a control oligonucleotide directed against luciferase (468.siLuc and BT.siLuc).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: species
B: homo sapiens (human) (aka homo sapiens)
C: probles
D: suborder
E: primate (aka primates)
F: None of the above. | B |
<Instruct>: Given the context 'This result disagrees with MUC1 activation of the AKT pathway in rat 3Y1 cells [18], and may reflect regulation more appropriate to breast cancer cells; this is supported by activation of AKT in response to MUC1 siRNA in other lines [21].', select the correct biomedical concept corresponding to 'rat'. Answer using one of the provided options. | <Options>: A: rats (aka rattus) (aka rattus)
B: rats (aka rattus sp.) (aka rattus sp.)
C: rattus norvegicus albus
D: rattus rattoides (aka rattus rattus)
E: rattus rattoides (aka rattus pyctoris)
F: None of the above. | F |
<Instruct>: Given the context 'Interestingly, 468.siMUC1 cells display somewhat decreased invasion on collagen IV, laminin, and fibronectin matrices, and on a no-matrix control (Figure 5c), which is in agreement with the trend towards decreased metastasis observed in Muc1-/- × MMTV-PyV MT mice [8].
', select the correct biomedical concept corresponding to 'mmtv'. Answer using one of the provided options. | <Options>: A: mouse mammary tumor virus (strain gr)
B: mouse mammary tumor virus (strain br6)
C: mouse mammary tumor virus, mmtv (aka mouse mammary tumor virus)
D: exogenous mouse mammary tumor virus
E: hmtv (aka human mammary tumor virus) (aka human mammary tumor virus)
F: None of the above. | C |
<Instruct>: Given the context 'Interestingly, 468.siMUC1 cells display somewhat decreased invasion on collagen IV, laminin, and fibronectin matrices, and on a no-matrix control (Figure 5c), which is in agreement with the trend towards decreased metastasis observed in Muc1-/- × MMTV-PyV MT mice [8].
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus (aka mus <genus>) (aka mus <genus>)
C: mus domesticus (aka mus musculus domesticus)
D: mouse (aka mus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | D |
<Instruct>: Given the context 'Interestingly, 468.siMUC1 cells display somewhat decreased invasion on collagen IV, laminin, and fibronectin matrices, and on a no-matrix control (Figure 5c), which is in agreement with the trend towards decreased metastasis observed in Muc1-/- × MMTV-PyV MT mice [8].
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus sp. (mice (aka mus sp.))
B: eastern european house mouse (aka mus musculus musculus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mus castaneus (aka mus musculus castaneus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | F |
<Instruct>: Given the context 'Discussion
This report describes both the transcriptional alterations seen after transfection with MUC1 siRNA in human breast cancer cells and the effects on events such as apoptosis and proliferation.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo (humans) (aka homo)
B: homo sapiens (human) (aka homo sapiens)
C: genus
D: this
E: biota (aka cellular organisms)
F: None of the above. | B |
<Instruct>: Given the context 'Both lines have epithelial morphology, form tumors slowly in nude mice [37], have mutant p53 [39,40], express EGFR', select the correct biomedical concept corresponding to 'nude mice'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: mice (aka mus <genus>) (aka mus <genus>)
C: delicate mouse (aka mus tenellus)
D: mouse (aka mus musculus)
E: mus molossinus (aka mus musculus molossinus)
F: None of the above. | D |
<Instruct>: Given the context 'First, though MMP-2 levels are increased in mouse mammary tumors, its expression is confined to the stroma', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: house mouse (aka mus musculus)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus molossinus (aka mus musculus molossinus)
E: peromyscus
F: None of the above. | B |
<Instruct>: Given the context 'Similarly, though MUC1 drives mammary oncogenesis in its own right [9] and facilitates tumorigenesis driven by other oncogenes [7,8], Muc1 is selectively down-regulated in c-neu-induced mouse mammary tumors', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: peromyscus
B: house mouse (aka mus musculus)
C: eastern european house mouse (aka mus musculus musculus)
D: western european house mouse (aka mus musculus domesticus)
E: mus <subgenus> (mus (aka mus <subgenus>))
F: None of the above. | B |
<Instruct>: Given the context 'Molecular cloning of four novel murine ribonuclease genes: unusual expansion within the ribonuclease A gene family.
', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: eastern european house mouse (aka mus musculus musculus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
F: None of the above. | A |
<Instruct>: Given the context 'Abstract
We have characterized four novel murine ribonuclease genes that, together with the murine eosinophil-associated ribonucleases 1 and 2, form a distinct and unusual cluster within the RNase A gene superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus domesticus (aka mus musculus domesticus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: house mouse (aka mus musculus)
D: mice (aka mus <genus>) (aka mus <genus>)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | C |
<Instruct>: Given the context 'Abstract
We have characterized four novel murine ribonuclease genes that, together with the murine eosinophil-associated ribonucleases 1 and 2, form a distinct and unusual cluster within the RNase A gene superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus domesticus (aka mus musculus domesticus)
C: mus sp. (mice (aka mus sp.))
D: mouse (aka mus musculus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | D |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus (aka mus <genus>) (aka mus <genus>)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mouse (aka mus musculus)
D: mus cricetus (aka cricetus cricetus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | C |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mice (aka mus <genus>) (aka mus <genus>)
B: mouse (aka mus musculus)
C: mus sp. (mice (aka mus sp.))
D: peromyscus
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | B |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: western european house mouse (aka mus musculus domesticus)
C: mus musculus (house mouse) (aka mus musculus)
D: mus sp. (mice (aka mus sp.))
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | C |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus domesticus (aka mus musculus domesticus)
C: mus cricetus (aka cricetus cricetus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus sp. (mice (aka mus sp.))
F: None of the above. | F |
<Instruct>: Given the context '� 1997 Oxford University Press
Nucleic Acids Research, 1997, Vol. 25, No. 21
4235�4239
Molecular cloning of four novel murine ribonuclease genes: unusual expansion within the Ribonuclease A gene family Dean Batten+, Kimberly D. Dyer, Joseph B. Domachowske� and Helene F. Rosenberg*', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus domesticus (aka mus musculus domesticus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus cricetus (aka cricetus cricetus)
E: mus (aka mus <genus>) (aka mus <genus>)
F: None of the above. | A |
<Instruct>: Given the context 'We have characterized four novel murine ribonuclease genes that, together with the murine eosinophilassociated ribonucleases 1 and 2, form a distinct and unusual cluster within the RNase A gene superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus domesticus (aka mus musculus domesticus)
B: mus sp. (mice (aka mus sp.))
C: mouse (aka mus musculus)
D: mus norvegicus (aka rattus norvegicus)
E: peromyscus
F: None of the above. | C |
<Instruct>: Given the context 'We have characterized four novel murine ribonuclease genes that, together with the murine eosinophilassociated ribonucleases 1 and 2, form a distinct and unusual cluster within the RNase A gene superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mouse (aka mus <genus>)
B: mouse (aka mus musculus)
C: peromyscus
D: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
E: mus <subgenus> (mus (aka mus <subgenus>))
F: None of the above. | B |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | A |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: mus cricetus (aka cricetus cricetus)
C: peromyscus
D: mouse (aka mus musculus)
E: mouse (aka mus <genus>)
F: None of the above. | D |
<Instruct>: Given the context 'Although the amino acid sequence similarities among these murine ribonucleases varies from 60 to 94%, they form a unique cluster, as each sequence is found to be more closely related to another of this group than to either murine angiogenin or to murine pancreatic ribonuclease.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: western european house mouse (aka mus musculus domesticus)
C: mouse (aka mus musculus)
D: mus sp. (mice (aka mus sp.))
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | C |
<Instruct>: Given the context 'INTRODUCTION Ribonuclease A (RNase A, bovine pancreatic ribonuclease) is the prototype of an enlarging family of proteins defined by distinctive elements of conserved primary structure and enzymatic activity (1,2).', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos bubalis (aka bubalus bubalis)
B: bovine (aka bos taurus)
C: bovidae
D: bos indicus (bos primigenius indicus) (aka bos indicus)
E: bovinae
F: None of the above. | B |
<Instruct>: Given the context 'Pancreatic ribonucleases (RNases 1) have been isolated from an extensive array of mammalian species (3,4), and mRNA encoding human pancreatic ribonuclease has been detected in
numerous somatic tissues in addition to pancreas (5).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: probles
B: mammals (aka mammalia)
C: primate (aka primates)
D: genus
E: human (aka homo sapiens)
F: None of the above. | E |
<Instruct>: Given the context 'RNases 2 and 3, eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP), respectively, have been characterized primarily with respect to eosinophil function (6,7), although expression of EDN [also known as RNase Us (8) or human liver ribonuclease (9)] is also widespread (5).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: human (aka homo sapiens)
B: kingdom
C: cellular organisms (biota) (aka cellular organisms)
D: mammals (aka mammalia)
E: macrobiotus sapiens
F: None of the above. | A |
<Instruct>: Given the context 'Recently, Larson and colleagues (15) described cDNAs encoding two highly homologous murine ribonucleases, the murine eosinophil-associated ribonucleases (mEAR) 1 and 2, which were cloned and identified via tryptic peptides isolated from murine eosinophil proteins.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: peromyscus
D: mus <genus> (mice (aka mus <genus>))
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Recently, Larson and colleagues (15) described cDNAs encoding two highly homologous murine ribonucleases, the murine eosinophil-associated ribonucleases (mEAR) 1 and 2, which were cloned and identified via tryptic peptides isolated from murine eosinophil proteins.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus cricetus (aka cricetus cricetus)
C: eastern european house mouse (aka mus musculus musculus)
D: mus norvegicus (aka rattus norvegicus)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | F |
<Instruct>: Given the context 'Recently, Larson and colleagues (15) described cDNAs encoding two highly homologous murine ribonucleases, the murine eosinophil-associated ribonucleases (mEAR) 1 and 2, which were cloned and identified via tryptic peptides isolated from murine eosinophil proteins.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus musculus (house mouse) (aka mus musculus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | B |
<Instruct>: Given the context 'Recently, Larson and colleagues (15) described cDNAs encoding two highly homologous murine ribonucleases, the murine eosinophil-associated ribonucleases (mEAR) 1 and 2, which were cloned and identified via tryptic peptides isolated from murine eosinophil proteins.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mus cricetus (aka cricetus cricetus)
D: mus musculus (house mouse) (aka mus musculus)
E: peromyscus
F: None of the above. | D |
<Instruct>: Given the context 'Although Southern analysis demonstrated that multiple copies of sequence homologous to mEAR-1 and mEAR-2 were present in murine genomic DNA, the precise nature of these copies--as pseudogenes, polymorphisms, or distinct functional genes--was unclear.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mus (aka mus <genus>) (aka mus <genus>)
C: mus sp. (mice (aka mus sp.))
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Together with mEAR-1 and mEAR-2, these six ribonuclease genes form an `mR cluster,' whose members are more closely related to one another than they are to other murine ribonucleases, yet whose position with respect to the defined RNase A lineages remains unclear.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus musculus (house mouse) (aka mus musculus)
E: peromyscus
F: None of the above. | D |
<Instruct>: Given the context 'MATERIALS AND METHODS Isolation of genomic fragments encoding murine ribonucleases by polymerase chain reaction (PCR) Genomic DNA was isolated from cells of the murine 3T3 fibroblast cell line.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: eastern european house mouse (aka mus musculus musculus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: house mouse (aka mus musculus)
E: peromyscus
F: None of the above. | D |
<Instruct>: Given the context 'MATERIALS AND METHODS Isolation of genomic fragments encoding murine ribonucleases by polymerase chain reaction (PCR) Genomic DNA was isolated from cells of the murine 3T3 fibroblast cell line.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: western european house mouse (aka mus musculus domesticus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mouse (aka mus musculus)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | D |
<Instruct>: Given the context 'Email: hr2k@nih.gov Present addresses: +Duke University School of Medicine, Durham, NC 27701, USA and �Department of Pediatrics, State University of New York-Health Sciences Center at Syracuse, Syracuse, NY 13210, USA
4236 Nucleic Acids Research, 1997, Vol. 25, No. 21
Figure 1. (A) Alignment of amino acid sequences encoded by six related murine ribonuclease genes.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mouse (aka mus musculus)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mice (aka mus <genus>) (aka mus <genus>)
D: mus norvegicus (aka rattus norvegicus)
E: mus sp. (mice (aka mus sp.))
F: None of the above. | A |
<Instruct>: Given the context 'GenBank accession numbers: mEAR (murine eosinophil-associated ribonuclease)-1, U72032; mEAR-2, U72031; mR (murine ribonuclease)-3, AF017258; mR-4, AF017259; mR-5, AF017260; mR-6P (pseudogene), AF017261.
', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: western european house mouse (aka mus musculus domesticus)
B: mice (aka mus <genus>) (aka mus <genus>)
C: mus musculus (house mouse) (aka mus musculus)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | C |
<Instruct>: Given the context 'GenBank accession numbers: mEAR (murine eosinophil-associated ribonuclease)-1, U72032; mEAR-2, U72031; mR (murine ribonuclease)-3, AF017258; mR-4, AF017259; mR-5, AF017260; mR-6P (pseudogene), AF017261.
', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: house mouse (aka mus musculus)
C: peromyscus
D: mus (aka mus <genus>) (aka mus <genus>)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | B |
<Instruct>: Given the context 'Northern analysis The murine multi-tissue Northern blot was purchased from Clontech, and pre-hybridized and hybridized as per manufacturer's instructions with radiolabelled oligonucleotide probes.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mus cricetus (aka cricetus cricetus)
D: peromyscus
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Northern analysis The murine multi-tissue Northern blot was purchased from Clontech, and pre-hybridized and hybridized as per manufacturer's instructions with radiolabelled oligonucleotide probes.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mice (aka mus sp.) (aka mus sp.)
D: mouse (aka mus <genus>)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | F |
<Instruct>: Given the context '4237 Nucleic Acids Research, 1997, Vol. 25, No. Nucleic Acids Research, 1994, Vol. 22, No. 121 4237
Figure 2. (A) Dendrogram depicting relationships among the eight characterized murine ribonucleases as determined by a modified UPGMA method (17).', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mus domesticus (aka mus musculus domesticus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mus <genus> (mice (aka mus <genus>))
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: peromyscus
C: eastern european house mouse (aka mus musculus musculus)
D: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus molossinus (aka mus musculus molossinus)
B: mus cricetus (aka cricetus cricetus)
C: house mouse (aka mus musculus)
D: peromyscus
E: mus sp. (mice (aka mus sp.))
F: None of the above. | C |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mice (aka mus sp.) (aka mus sp.)
B: peromyscus
C: mice (aka mus <genus>) (aka mus <genus>)
D: house mouse (aka mus musculus)
E: mus <subgenus> (mus (aka mus <subgenus>))
F: None of the above. | D |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: primate (aka primates)
B: macrobiotus sapiens
C: eutherian mammals (aka eutheria)
D: homo sapiens (human) (aka homo sapiens)
E: cellular organisms (biota) (aka cellular organisms)
F: None of the above. | D |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: kingdom
B: suborder
C: probles
D: homo sapiens (human) (aka homo sapiens)
E: species
F: None of the above. | D |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: species
B: macrobiotus sapiens
C: human (aka homo sapiens)
D: this
E: birds (aka aves)
F: None of the above. | C |
<Instruct>: Given the context 'Abbreviations are as in Figure 1A, also mPR (murine pancreatic ribonuclease, sw:rnp_mouse), mANG (murine angiogenin, U72672), hEDN (human eosinophil-derived neurotoxin, M24157), hECP (human eosinophil cationic protein, X15161), hRK6 (human ribonuclease k6, U64998), pRK6 (porcine kidney ribonuclease (24), and bRK6 (bovine kidney ribonuclease, sw:rnkd_bovin).', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos bubalis bubalis (aka bubalus bubalis bubalis)
B: bos taurus x bos indicus (aka bos indicus x bos taurus)
C: bos bovis (aka bos taurus)
D: bovidae
E: boveria
F: None of the above. | C |
<Instruct>: Given the context 'Amino acid sequence comparisons of murine and human ribonucleases
Sequence analysis All DNA sequence analysis and comparisons were performed with the assistance of the Wisconsin Genetics Computer Group and Sequencher (Gene Codes Corporation) programs available at the National Institutes of Health.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus sp. (mice (aka mus sp.))
B: mus musculus (house mouse) (aka mus musculus)
C: western european house mouse (aka mus musculus domesticus)
D: mus cricetus (aka cricetus cricetus)
E: mus norvegicus (aka rattus norvegicus)
F: None of the above. | B |
<Instruct>: Given the context 'Amino acid sequence comparisons of murine and human ribonucleases
Sequence analysis All DNA sequence analysis and comparisons were performed with the assistance of the Wisconsin Genetics Computer Group and Sequencher (Gene Codes Corporation) programs available at the National Institutes of Health.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: animals (aka metazoa)
B: kingdom
C: suborder
D: homo sapiens (human) (aka homo sapiens)
E: primate (aka primates)
F: None of the above. | D |
<Instruct>: Given the context 'Amino acid sequence comparisons of murine and human ribonucleases
Sequence analysis All DNA sequence analysis and comparisons were performed with the assistance of the Wisconsin Genetics Computer Group and Sequencher (Gene Codes Corporation) programs available at the National Institutes of Health.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: kingdom
B: probles
C: macrobiotus sapiens
D: suborder
E: placental mammals (aka eutheria)
F: None of the above. | F |
<Instruct>: Given the context 'RESULTS Isolation of genomic fragments encoding novel murine ribonucleases The alignment in Figure 1A displays the amino acid sequences encoded by the six related ribonuclease genes.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: peromyscus
C: mus cricetus (aka cricetus cricetus)
D: house mouse (aka mus musculus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | D |
<Instruct>: Given the context 'Murine eosinophil-associated ribonucleases-1 and -2 (mEAR-1 and mEAR-2) are the predicted amino acid sequences from two genes described previously by Larson and colleagues (15); murine ribonucleases 3, 4, 5 and 6-pseudogene (mR-3, mR-4, mR-5 and mR-6P), are the predicted amino acid sequences encoded by novel DNA
hEDN mEAR-1 mEAR-2 mR-3 mR-4 mR-5 mANG mPR 56 56 54 60 60 43 53
hECP 59 59 57 59 58 49 52
hRK6 58 59 59 53 56 49 59
hPR 47 48 49 48 57 55 79
hR4 50 53 51 52 54 57 66
hANG 49 48 51 47 47 80 60
Values are expressed as percent similarity between pairs of amino acid sequences as determined by the BESTFIT algorithm of the Wisconsin Genetics Computer Group program on-line at the National Institutes of Health.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus norvegicus (aka rattus norvegicus)
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mus musculus (house mouse) (aka mus musculus)
E: peromyscus
F: None of the above. | D |
<Instruct>: Given the context 'Murine eosinophil-associated ribonucleases-1 and -2 (mEAR-1 and mEAR-2) are the predicted amino acid sequences from two genes described previously by Larson and colleagues (15); murine ribonucleases 3, 4, 5 and 6-pseudogene (mR-3, mR-4, mR-5 and mR-6P), are the predicted amino acid sequences encoded by novel DNA
hEDN mEAR-1 mEAR-2 mR-3 mR-4 mR-5 mANG mPR 56 56 54 60 60 43 53
hECP 59 59 57 59 58 49 52
hRK6 58 59 59 53 56 49 59
hPR 47 48 49 48 57 55 79
hR4 50 53 51 52 54 57 66
hANG 49 48 51 47 47 80 60
Values are expressed as percent similarity between pairs of amino acid sequences as determined by the BESTFIT algorithm of the Wisconsin Genetics Computer Group program on-line at the National Institutes of Health.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus norvegicus (aka rattus norvegicus)
D: mus musculus (house mouse) (aka mus musculus)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | D |
<Instruct>: Given the context 'Abbreviations are as defined in Figures 1 and 2, and also include hR4 (human ribonuclease 4, sw:rnl4_human), hANG (human angiogenin, M11567), and hPR (human pancreatic ribonuclease, X62946).
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo sapiens (human) (aka homo sapiens)
B: mammals (aka mammalia)
C: primate (aka primates)
D: placental mammals (aka eutheria)
E: macrobiotus sapiens
F: None of the above. | A |
<Instruct>: Given the context 'Abbreviations are as defined in Figures 1 and 2, and also include hR4 (human ribonuclease 4, sw:rnl4_human), hANG (human angiogenin, M11567), and hPR (human pancreatic ribonuclease, X62946).
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: human (aka homo sapiens)
B: this
C: placental mammals (aka eutheria)
D: suborder
E: macrobiotus sapiens
F: None of the above. | A |
<Instruct>: Given the context 'Abbreviations are as defined in Figures 1 and 2, and also include hR4 (human ribonuclease 4, sw:rnl4_human), hANG (human angiogenin, M11567), and hPR (human pancreatic ribonuclease, X62946).
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo sapiens (human) (aka homo sapiens)
B: species
C: avian (aka aves)
D: primate (aka primates)
E: placental mammals (aka eutheria)
F: None of the above. | A |
<Instruct>: Given the context 'Abbreviations are as defined in Figures 1 and 2, and also include hR4 (human ribonuclease 4, sw:rnl4_human), hANG (human angiogenin, M11567), and hPR (human pancreatic ribonuclease, X62946).
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: humans (aka homo)
B: homo sapiens (human) (aka homo sapiens)
C: suborder
D: probles
E: placental mammals (aka eutheria)
F: None of the above. | B |
<Instruct>: Given the context '4238 Nucleic Acids Research, 1997, Vol. 25, No. 21 fragments amplified from murine genomic DNA.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mus domesticus (aka mus musculus domesticus)
C: mouse (aka mus musculus)
D: mus norvegicus (aka rattus norvegicus)
E: mus <genus> (mice (aka mus <genus>))
F: None of the above. | C |
<Instruct>: Given the context 'Relationships among the murine ribonucleases A dendrogram depicting the relationships among several of the murine and human ribonucleases is shown in Figure 2A.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mouse (aka mus musculus)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | D |
<Instruct>: Given the context 'Relationships among the murine ribonucleases A dendrogram depicting the relationships among several of the murine and human ribonucleases is shown in Figure 2A.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mouse (aka mus musculus)
C: mus sp. (mice (aka mus sp.))
D: peromyscus
E: mus (aka mus <genus>) (aka mus <genus>)
F: None of the above. | B |
<Instruct>: Given the context 'Relationships among the murine ribonucleases A dendrogram depicting the relationships among several of the murine and human ribonucleases is shown in Figure 2A.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: western european house mouse (aka mus musculus domesticus)
B: mus sp. (mice (aka mus sp.))
C: mus cricetus (aka cricetus cricetus)
D: mus <genus> (mice (aka mus <genus>))
E: mus norvegicus (aka rattus norvegicus)
F: None of the above. | F |
<Instruct>: Given the context 'Relationships among the murine ribonucleases A dendrogram depicting the relationships among several of the murine and human ribonucleases is shown in Figure 2A.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: birds (aka aves)
B: animals (aka metazoa)
C: mammals (aka mammalia)
D: human (aka homo sapiens)
E: eutherian mammals (aka eutheria)
F: None of the above. | D |
<Instruct>: Given the context 'These six sequences are more closely related to one another than they are to either murine pancreatic ribonuclease (mPR) or to murine angiogenin (mANG) or to any of the three human ribonucleases shown (hEDN, hECP or hRK6).', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus norvegicus (aka rattus norvegicus)
C: mouse (aka mus musculus)
D: mus sp. (mice (aka mus sp.))
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | C |
<Instruct>: Given the context 'These six sequences are more closely related to one another than they are to either murine pancreatic ribonuclease (mPR) or to murine angiogenin (mANG) or to any of the three human ribonucleases shown (hEDN, hECP or hRK6).', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus musculus (house mouse) (aka mus musculus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mus <genus> (mice (aka mus <genus>))
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | B |
<Instruct>: Given the context 'These six sequences are more closely related to one another than they are to either murine pancreatic ribonuclease (mPR) or to murine angiogenin (mANG) or to any of the three human ribonucleases shown (hEDN, hECP or hRK6).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo (humans) (aka homo)
B: kingdom
C: avian (aka aves)
D: macrobiotus sapiens
E: human (aka homo sapiens)
F: None of the above. | E |
<Instruct>: Given the context 'Northern analysis Tissue-specific expression of mRNA encoding these murine ribonucleases is shown in Figure 3.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: house mouse (aka mus musculus)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | C |
<Instruct>: Given the context 'A prominent mRNA of 1.8 kb was also detected in mRNA isolated from murine testicular tissue; fainter hybridizing mRNAs of varying size were detected in lung and skeletal muscle.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: eastern european house mouse (aka mus musculus musculus)
C: mus sp. (mice (aka mus sp.))
D: mus musculus (house mouse) (aka mus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | D |
<Instruct>: Given the context 'The size variation may represent differential splicing of the mR-5-encoding mRNA, or may represent mRNAs encoding one or more as yet undiscovered murine ribonucleases that are more closely related to mR-5 than those whose sequences are reported here.
', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mus cricetus (aka cricetus cricetus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: house mouse (aka mus musculus)
E: peromyscus
F: None of the above. | D |
<Instruct>: Given the context 'Figure 3. (A) Murine RNA probed with a 32 bp oligonucleotide complementary to mEAR-1, mEAR-2 and mR-3 coding sequences.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mus cricetus (aka cricetus cricetus)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context '(C) Same as in (A), probed with a 48 bp oligonucleotide complementary to human actin (16), demonstrating relative loading of each lane.
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo sapiens (human) (aka homo sapiens)
B: this
C: suborder
D: avian (aka aves)
E: probles
F: None of the above. | A |
<Instruct>: Given the context 'Relationship to human ribonucleases The data in Table 1 denote the amino acid sequence similarity between pairs of murine and human ribonucleases of the RNase A superfamily.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: placental mammals (aka eutheria)
B: macrobiotus sapiens
C: homo sapiens (human) (aka homo sapiens)
D: homo (humans) (aka homo)
E: species
F: None of the above. | C |
<Instruct>: Given the context 'Relationship to human ribonucleases The data in Table 1 denote the amino acid sequence similarity between pairs of murine and human ribonucleases of the RNase A superfamily.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: species
B: probles
C: mammals (aka mammalia)
D: kingdom
E: biota (aka cellular organisms)
F: None of the above. | F |
<Instruct>: Given the context 'Relationship to human ribonucleases The data in Table 1 denote the amino acid sequence similarity between pairs of murine and human ribonucleases of the RNase A superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus cricetus (aka cricetus cricetus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: peromyscus
E: house mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Relationship to human ribonucleases The data in Table 1 denote the amino acid sequence similarity between pairs of murine and human ribonucleases of the RNase A superfamily.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: kingdom
B: eutherian mammals (aka eutheria)
C: biota (aka cellular organisms)
D: human (aka homo sapiens)
E: species
F: None of the above. | D |
<Instruct>: Given the context 'Although the sequences of the mEAR-1/mEAR-2/mR-3 subgroup are slightly more similar to ECP and RNase k6, and mR-4 and mR-5, to EDN and ECP, the orthologous relationships of these murine ribonucleases cannot be discerned from these data.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: eastern european house mouse (aka mus musculus musculus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: house mouse (aka mus musculus)
E: mus <genus> (mice (aka mus <genus>))
F: None of the above. | D |
<Instruct>: Given the context 'This stands in direct contrast to mPR and mANG, whose human orthologs can be clearly distinguished on the basis of their amino acid sequence homologies.
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: genus
B: cellular organisms (biota) (aka cellular organisms)
C: probles
D: macrobiotus sapiens
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | E |
<Instruct>: Given the context 'DISCUSSION In this work, we have identified four novel murine ribonuclease genes that, together with mEAR-1 and mEAR-2 defined by Larson and colleagues (15), form an unusual cluster within the RNase A gene superfamily.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: western european house mouse (aka mus musculus domesticus)
C: mouse (aka mus musculus)
D: mouse (aka mus <genus>)
E: mus norvegicus (aka rattus norvegicus)
F: None of the above. | C |
<Instruct>: Given the context 'The six genes within this cluster have varying amino acid sequence homologies to one another, but are clearly more closely related to one another than to either murine pancreatic ribonuclease (mPR) or angiogenin (mANG), or to any of the human ribonucleases of the RNase A family.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: peromyscus
B: house mouse (aka mus musculus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mus norvegicus (aka rattus norvegicus)
E: mus (aka mus <genus>) (aka mus <genus>)
F: None of the above. | B |
<Instruct>: Given the context 'The six genes within this cluster have varying amino acid sequence homologies to one another, but are clearly more closely related to one another than to either murine pancreatic ribonuclease (mPR) or angiogenin (mANG), or to any of the human ribonucleases of the RNase A family.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: animals (aka metazoa)
B: genus
C: cellular organisms (biota) (aka cellular organisms)
D: macrobiotus sapiens
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | E |
<Instruct>: Given the context 'These results suggest that the `mR cluster' emerged via multiple duplications of a gene that had already diverged from those encoding the other murine ribonucleases.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: eastern european house mouse (aka mus musculus musculus)
B: house mouse (aka mus musculus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | B |
<Instruct>: Given the context 'Although this type of expansion is unusual in this gene family, it is actually not unique; similar expansion has occurred in bovine species, with gene duplication resulting in the three closely-related bovine pancreatic, bovine brain (19,20) and bovine seminal (21) ribonucleases.', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos bubalis (aka bubalus bubalis)
B: boveria
C: dairy cow (aka bos taurus)
D: bos taurus x bos indicus (aka bos indicus x bos taurus)
E: bovinae
F: None of the above. | C |
<Instruct>: Given the context 'Although this type of expansion is unusual in this gene family, it is actually not unique; similar expansion has occurred in bovine species, with gene duplication resulting in the three closely-related bovine pancreatic, bovine brain (19,20) and bovine seminal (21) ribonucleases.', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos (cattle) (aka bos)
B: ox (aka bos taurus) (aka bos taurus)
C: boveria
D: bos taurus x bos indicus (aka bos indicus x bos taurus)
E: bos indicus (bos primigenius indicus) (aka bos indicus)
F: None of the above. | B |
<Instruct>: Given the context 'Although this type of expansion is unusual in this gene family, it is actually not unique; similar expansion has occurred in bovine species, with gene duplication resulting in the three closely-related bovine pancreatic, bovine brain (19,20) and bovine seminal (21) ribonucleases.', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bovidae
B: bovinae
C: cattle (aka bos)
D: bos taurus x bos indicus (aka bos indicus x bos taurus)
E: bos sp.
F: None of the above. | F |
<Instruct>: Given the context 'Although this type of expansion is unusual in this gene family, it is actually not unique; similar expansion has occurred in bovine species, with gene duplication resulting in the three closely-related bovine pancreatic, bovine brain (19,20) and bovine seminal (21) ribonucleases.', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: cattle (aka bos)
B: bos taurus indicus (aka bos indicus)
C: bos bovis (aka bos taurus)
D: bos bubalis (aka bubalus bubalis)
E: bovidae
F: None of the above. | C |
<Instruct>: Given the context 'Although this type of expansion is unusual in this gene family, it is actually not unique; similar expansion has occurred in bovine species, with gene duplication resulting in the three closely-related bovine pancreatic, bovine brain (19,20) and bovine seminal (21) ribonucleases.', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos sp.
B: cow (aka bos taurus) (aka bos taurus)
C: boveria
D: bos bubalis bubalis (aka bubalus bubalis bubalis)
E: bos bubalis (aka bubalus bubalis)
F: None of the above. | B |
<Instruct>: Given the context 'One interesting feature of the mR cluster is that its relationship to any of to the six known human RNase A-type genes cannot be
4239 Nucleic Acids Research, 1997, Vol. 25, No.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: placental mammals (aka eutheria)
B: homo sapiens (human) (aka homo sapiens)
C: probles
D: kingdom
E: suborder
F: None of the above. | B |
<Instruct>: Given the context 'Although the amino acid sequences encoded by mEAR-1 and mEAR-2 match those of tryptic peptides derived from murine eosinophil proteins (15), the homology data do not stand in overwhelming support of a unique relationship between any of the mR cluster ribonucleases and the human eosinophil ribonucleases EDN and ECP.', select the correct biomedical concept corresponding to 'murine'. Answer using one of the provided options. | <Options>: A: mouse (aka mus musculus)
B: peromyscus
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mus domesticus (aka mus musculus domesticus)
E: mus norvegicus (aka rattus norvegicus)
F: None of the above. | A |
<Instruct>: Given the context 'Although the amino acid sequences encoded by mEAR-1 and mEAR-2 match those of tryptic peptides derived from murine eosinophil proteins (15), the homology data do not stand in overwhelming support of a unique relationship between any of the mR cluster ribonucleases and the human eosinophil ribonucleases EDN and ECP.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: probles
B: biota (aka cellular organisms)
C: this
D: homo (humans) (aka homo)
E: human (aka homo sapiens)
F: None of the above. | E |
<Instruct>: Given the context 'The existence of an additional, as yet unidentified human ribonuclease (or ribonucleases) more closely related to those of the mR cluster cannot be ruled out.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: animals (aka metazoa)
B: species
C: humans (aka homo)
D: human (aka homo sapiens)
E: avian (aka aves)
F: None of the above. | D |
<Instruct>: Given the context 'On this point, a number of studies have suggested a distinct role for the human ribonuclease ECP in eosinophil-mediated host defense (6,7); in addition, we have recently shown that eosinophil ribonucleases can inhibit retroviral transduction of human target cells (23).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: this
B: suborder
C: kingdom
D: homo (humans) (aka homo)
E: human (aka homo sapiens)
F: None of the above. | E |
<Instruct>: Given the context 'On this point, a number of studies have suggested a distinct role for the human ribonuclease ECP in eosinophil-mediated host defense (6,7); in addition, we have recently shown that eosinophil ribonucleases can inhibit retroviral transduction of human target cells (23).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: genus
B: primate (aka primates)
C: placental mammals (aka eutheria)
D: animals (aka metazoa)
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | E |
<Instruct>: Given the context 'Molecular polymorphism, differentiation and introgression in the period gene between Lutzomyia intermedia and Lutzomyia whitmani
Abstract
Background
Lutzomyia intermedia and Lutzomyia whitmani (Diptera: Psychodidae) are important and very closely related vector species of cutaneous leishmaniasis in Brazil, which are distinguishable by a few morphological differences.', select the correct biomedical concept corresponding to 'lutzomyia intermedia'. Answer using one of the provided options. | <Options>: A: jungermannia intermedia (aka frullania intermedia)
B: lutzomyia (nyssomyia) intermedia (aka nyssomyia intermedia)
C: parolinia intermedia
D: harttiella intermedia
E: lepidodermella intermedia
F: None of the above. | B |
<Instruct>: Given the context 'Molecular polymorphism, differentiation and introgression in the period gene between Lutzomyia intermedia and Lutzomyia whitmani
Abstract
Background
Lutzomyia intermedia and Lutzomyia whitmani (Diptera: Psychodidae) are important and very closely related vector species of cutaneous leishmaniasis in Brazil, which are distinguishable by a few morphological differences.', select the correct biomedical concept corresponding to 'lutzomyia whitmani'. Answer using one of the provided options. | <Options>: A: bavayia whitakeri
B: orobdella whitmani
C: metrosideros whitakeri
D: chionodes whitmanella
E: flebotomus whitmani (aka nyssomyia whitmani)
F: None of the above. | E |
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