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<Instruct>: Given the context 'The results showed that of the total 14 miRNAs encoded by MDV1, MDV1-miR-M3 significantly promoted cell survival under treatment with cisplatin, a widely used chemotherapy drug.', select the correct biomedical concept corresponding to 'mdv1'. Answer using one of the provided options.
<Options>: A: murine adenovirus type 1 mav1 (aka murine adenovirus 1) B: maryland calicivirus 1 (mdv1 (aka maryland calicivirus 1)) C: marten adenovirus type 1 D: marek's disease virus mdv (aka gallid alphaherpesvirus 2) E: medway virus F: None of the above.
D
<Instruct>: Given the context 'MDV1-miR-M3 suppressed cisplatin-induced apoptosis by directly downregulating expression at the protein but not the mRNA level of Smad2, a critical component in the transforming growth factor Beta signal pathway.', select the correct biomedical concept corresponding to 'mdv1'. Answer using one of the provided options.
<Options>: A: marr virus B: marten adenovirus type 1 C: medway virus D: marek's disease virus serotype 1 mdv-1 (aka gallid alphaherpesvirus 2) E: human mastadenovirus 1 (aka human adenovirus 1) F: None of the above.
D
<Instruct>: Given the context 'Differentially expressed genes in silkworm cell cultures in response to infection by Wolbachia and Cardinium endosymbionts. ', select the correct biomedical concept corresponding to 'silkworm'. Answer using one of the provided options.
<Options>: A: beet armyworm (aka spodoptera exigua) B: bombyx C: bombyx timon (aka pygaera timon) D: domestic silkworm (aka bombyx mori) E: bombus morio (apis morio) (aka bombus morio) F: None of the above.
D
<Instruct>: Given the context 'Here we studied differentially expressed genes in Wolbachia- and Cardinium-infected Bm-aff3 silkworm cells using a silkworm microarray.', select the correct biomedical concept corresponding to 'silkworm'. Answer using one of the provided options.
<Options>: A: bombus hortorum (apis hortorum) (aka bombus hortorum) B: cotton bollworm (aka helicoverpa armigera) C: domestic silkworm (aka bombyx mori) D: silkworm moths (aka bombycidae) E: beet armyworm (aka spodoptera exigua) F: None of the above.
C
<Instruct>: Given the context 'Here we studied differentially expressed genes in Wolbachia- and Cardinium-infected Bm-aff3 silkworm cells using a silkworm microarray.', select the correct biomedical concept corresponding to 'silkworm'. Answer using one of the provided options.
<Options>: A: silk moth (aka bombyx mori) B: bombyx timon (aka pygaera timon) C: bombyx catax (aka eriogaster catax) D: wild silkworm (aka bombyx mandarina) E: bombyx F: None of the above.
A
<Instruct>: Given the context 'We present the characterization of the PEVK domain in two dragonflies and in human lice.', select the correct biomedical concept corresponding to 'human lice'. Answer using one of the provided options.
<Options>: A: licinus B: chewing lice (aka ischnocera) C: human head louse (aka pediculus humanus capitis) D: head lice (aka pediculus humanus) E: body lice (aka pediculidae) F: None of the above.
D
<Instruct>: Given the context 'T cell-mediated protection against lethal 2009 pandemic H1N1 influenza virus infection in a mouse model. ', select the correct biomedical concept corresponding to 'lethal 2009 pandemic h1n1 influenza virus'. Answer using one of the provided options.
<Options>: A: influenza b virus (b/california/01/2009) B: influenza a virus (a/california/11/2009(h1n1)) C: influenza a virus (a/england/751/2009(h1n1)) D: influenza a virus (human influenza a virus) (aka influenza a virus) E: influenza a virus (a/england/712/2009(h1n1)) F: None of the above.
D
<Instruct>: Given the context 'Genetic mutation and reassortment of influenza virus gene segments, in particular those of hemagglutinin (HA) and neuraminidase (NA), that lead to antigenic drift and shift are the major strategies for influenza virus to escape preexisting immunity.', select the correct biomedical concept corresponding to 'influenza virus'. Answer using one of the provided options.
<Options>: A: influenza virus type a (aka influenza a virus) B: influenza virus (aka unidentified influenza virus) C: swine influenza virus D: equine influenza virus E: alphainfluenzavirus (influenzavirus a) (aka alphainfluenzavirus) F: None of the above.
B
<Instruct>: Given the context 'Genetic mutation and reassortment of influenza virus gene segments, in particular those of hemagglutinin (HA) and neuraminidase (NA), that lead to antigenic drift and shift are the major strategies for influenza virus to escape preexisting immunity.', select the correct biomedical concept corresponding to 'influenza virus'. Answer using one of the provided options.
<Options>: A: influenza b virus (influenza virus type b) (aka influenza b virus) B: swine influenza virus C: influenza virus type c (aka influenza c virus) D: influenzavirus a (aka alphainfluenzavirus) E: influenzavirus c (aka gammainfluenzavirus) F: None of the above.
F
<Instruct>: Given the context 'Genetic mutation and reassortment of influenza virus gene segments, in particular those of hemagglutinin (HA) and neuraminidase (NA), that lead to antigenic drift and shift are the major strategies for influenza virus to escape preexisting immunity.', select the correct biomedical concept corresponding to 'influenza virus'. Answer using one of the provided options.
<Options>: A: swine influenza virus B: influenzavirus (aka unidentified influenza virus) C: influenzavirus c (aka gammainfluenzavirus) D: influenza virus type c (aka influenza c virus) E: equine influenza virus F: None of the above.
B
<Instruct>: Given the context 'The most recent example of such phenomena is the first pandemic of H1N1 influenza of the 21st century, which started in 2009.', select the correct biomedical concept corresponding to 'h1n1 influenza'. Answer using one of the provided options.
<Options>: A: h1n1 swine influenza virus B: influenzavirus a (aka alphainfluenzavirus) C: influenza a virus (a/china) D: human influenza a virus (aka influenza a virus) E: flubv (aka influenza b virus) F: None of the above.
D
<Instruct>: Given the context 'Cross-reactive antibodies raised against H1N1 viruses circulating before 1930 show protective activity against the 2009 pandemic virus.', select the correct biomedical concept corresponding to 'h1n1 viruses'. Answer using one of the provided options.
<Options>: A: fluruvirus B: h1n1 swine influenza virus C: swine influenza virus D: human influenza a virus (aka influenza a virus) E: influenza b virus (influenza virus type b) (aka influenza b virus) F: None of the above.
D
<Instruct>: Given the context 'Cross-reactive antibodies raised against H1N1 viruses circulating before 1930 show protective activity against the 2009 pandemic virus.', select the correct biomedical concept corresponding to '2009 pandemic virus'. Answer using one of the provided options.
<Options>: A: h1n1 swine influenza virus B: fluav (aka influenza a virus) C: influenza a virus (a/england/759/2009(h1n1)) D: influenza b virus (b/california/02/2009) E: influenza b virus (b/california/01/2009) F: None of the above.
B
<Instruct>: Given the context 'To explore the protection mechanisms in vivo, we primed mice with H1 and H3 influenza virus isolates and rechallenged them with a virus derived from the 2009 H1N1 A/CA/04/09 virus, named CA/E3/09.', select the correct biomedical concept corresponding to 'h1'. Answer using one of the provided options.
<Options>: A: h11n4 subtype B: h1n2 (aka h1n2 subtype) (aka h1n2 subtype) C: h1n9 subtype D: h11n5 subtype E: h11n6 subtype F: None of the above.
F
<Instruct>: Given the context 'To explore the protection mechanisms in vivo, we primed mice with H1 and H3 influenza virus isolates and rechallenged them with a virus derived from the 2009 H1N1 A/CA/04/09 virus, named CA/E3/09.', select the correct biomedical concept corresponding to 'h3 influenza virus'. Answer using one of the provided options.
<Options>: A: human influenza a virus (aka influenza a virus) B: influenza virus type c (aka influenza c virus) C: h3n8 equine influenza virus (aka equine influenza virus h3n8) D: avian influenza virus (aka unidentified influenza virus) E: h1n1 swine influenza virus F: None of the above.
A
<Instruct>: Given the context 'To explore the protection mechanisms in vivo, we primed mice with H1 and H3 influenza virus isolates and rechallenged them with a virus derived from the 2009 H1N1 A/CA/04/09 virus, named CA/E3/09.', select the correct biomedical concept corresponding to '2009 h1n1 a/ca/04/09 virus'. Answer using one of the provided options.
<Options>: A: influenza a virus (a/california/07-00001/2009(h1n1)) B: influenza a virus (a/california/07-00005/2009(h1n1)) C: influenza a virus (a/california/vrdl4/2009(h1n1)) D: influenza b virus (b/california/01/2009) E: influenza a virus (a/california/09/2010(h1n1)) F: None of the above.
F
<Instruct>: Given the context 'We found that priming with influenza viruses of both H1 and H3 homo- and heterosubtypes protected against lethal CA/E3/09 virus challenge.', select the correct biomedical concept corresponding to 'h1'. Answer using one of the provided options.
<Options>: A: h11n3 subtype B: h11n4 subtype C: h1n4 subtype D: h1n7 subtype E: h1n6 subtype F: None of the above.
F
<Instruct>: Given the context 'Taken together, these results indicate that cross-reactive T cells established after initial priming with distally related viruses can be a vital component for prevention of disease and control of pandemic H1N1 influenza virus infection.', select the correct biomedical concept corresponding to 'pandemic h1n1 influenza virus'. Answer using one of the provided options.
<Options>: A: influenza a virus (a/china) B: h1n1 swine influenza virus C: influenza virus type b (aka influenza b virus) D: influenza virus (aka unidentified influenza virus) E: influenza a virus (human influenza a virus) (aka influenza a virus) F: None of the above.
E
<Instruct>: Given the context 'Dermamoeba algensis n. sp. (Amoebozoa, Dermamoebidae): an algivorous lobose amoeba with complex cell coat and unusual feeding mode. ', select the correct biomedical concept corresponding to 'dermamoeba algensis n. sp.'. Answer using one of the provided options.
<Options>: A: entamoeba muris B: dermamoebida sp. C: dermamoeba algensis D: entamoeba sp. do E: entamoeba insolita F: None of the above.
C
<Instruct>: Given the context 'Dermamoeba algensis n. sp. (Amoebozoa, Dermamoebidae): an algivorous lobose amoeba with complex cell coat and unusual feeding mode. ', select the correct biomedical concept corresponding to 'dermamoeba algensis n. sp.'. Answer using one of the provided options.
<Options>: A: entamoeba insolita B: entamoeba dispar C: acanthamoeba griffini D: entamoeba ecuadoriensis E: entamoeba bovis F: None of the above.
F
<Instruct>: Given the context 'In this paper we describe a third species of this genus, D. algensis n. sp.', select the correct biomedical concept corresponding to 'd. algensis n. sp.'. Answer using one of the provided options.
<Options>: A: dientamoeba fragilis B: hedera algeriensis C: daphniopsis queenslandensis (aka daphnia queenslandensis) D: daphnia muddensis E: dermamoeba algensis F: None of the above.
E
<Instruct>: Given the context 'Accordingly, D. algensis has a wide range of salinity tolerance. ', select the correct biomedical concept corresponding to 'd. algensis'. Answer using one of the provided options.
<Options>: A: dermamoeba algensis B: drepanepteryx algida C: daphnia muddensis D: daphnia nivalis E: kordia algicida F: None of the above.
A
<Instruct>: Given the context 'Clinical management of Staphylococcus aureus bacteraemia. Staphylococcus aureus bacteraemia is one of the most common serious bacterial infections worldwide.', select the correct biomedical concept corresponding to 'staphylococcus aureus'. Answer using one of the provided options.
<Options>: A: 'staphylococcus faecalis' (aka staphylococcus faecalis) B: staphylococcus epidermidis albus (aka staphylococcus epidermidis) C: micrococcus aureus (aka staphylococcus aureus) D: staphylococcus equorum E: staphylococcus hominis F: None of the above.
C
<Instruct>: Given the context 'Clinical management of Staphylococcus aureus bacteraemia. Staphylococcus aureus bacteraemia is one of the most common serious bacterial infections worldwide.', select the correct biomedical concept corresponding to 'staphylococcus aureus'. Answer using one of the provided options.
<Options>: A: staphylococcus pyogenes aureus (aka staphylococcus aureus) B: 'staphylococcus faecalis' (aka staphylococcus faecalis) C: staphylococcus equorum D: staphylococcus haemolyticus E: streptomyces aureus F: None of the above.
A
<Instruct>: Given the context 'To date, fewer than 1500 patients with S aureus bacteraemia have been recruited to 16 controlled trials of antimicrobial therapy.', select the correct biomedical concept corresponding to 's aureus'. Answer using one of the provided options.
<Options>: A: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus) B: staphylococcus haemolyticus C: staphylococcus (aurococcus) (aka staphylococcus) D: staphylococcus epidermidis (staphylococcus epidermidis albus) (aka staphylococcus epidermidis) E: arthrobacter aureus ('arthrobacter aureus') (aka arthrobacter aureus) F: None of the above.
A
<Instruct>: Given the context 'Here, we propose and review ten unanswered clinical questions commonly posed by those managing S aureus bacteraemia.', select the correct biomedical concept corresponding to 's aureus'. Answer using one of the provided options.
<Options>: A: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis) B: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus) C: agaribacillus aureus D: staphylococcus epidermidis (staphylococcus epidermidis albus) (aka staphylococcus epidermidis) E: staphylococcus haemolyticus F: None of the above.
B
<Instruct>: Given the context 'Our findings define the major areas of uncertainty in the management of S aureus bacteraemia and highlight just two key principles.', select the correct biomedical concept corresponding to 's aureus'. Answer using one of the provided options.
<Options>: A: staphylococcus aureus (staphylococcus aureus subsp. anaerobius) (aka staphylococcus aureus) B: streptococcus hemolyticus (aka streptococcus pyogenes) C: arthrobacter aureus ('arthrobacter aureus') (aka arthrobacter aureus) D: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis) E: streptomyces aureus F: None of the above.
A
<Instruct>: Given the context 'Beyond this, the best drugs, dose, mode of delivery, and duration of therapy are uncertain, a situation compounded by emerging S aureus strains that are resistant to old and new antibiotics.', select the correct biomedical concept corresponding to 's aureus'. Answer using one of the provided options.
<Options>: A: streptomyces aureus B: micrococcus aureus (aka staphylococcus aureus) C: staphylococcus equorum D: staphylococcus epidermidis albus (aka staphylococcus epidermidis) E: staphylococcus aureus strain pa (aka staphylococcus aureus pa) F: None of the above.
B
<Instruct>: Given the context 'Key data gaps include incidence and case-fatality ratios for all ages, the contribution of influenza towards admission of adults to hospital for ARI, representative seasonality data, economic burden, and the interaction of influenza with prevalent disorders in Africa, such as malaria, HIV, and malnutrition. ', select the correct biomedical concept corresponding to 'hiv'. Answer using one of the provided options.
<Options>: A: aids virus (aka human immunodeficiency virus 2) B: human immunodeficiency virus 3 (hiv (aka human immunodeficiency virus 3)) C: human immunodeficiency virus (hiv (aka human immunodeficiency virus)) D: human immunodeficiency virus 1 (human immunodeficiency virus type 1, hiv-1) (aka human immunodeficiency virus 1) E: None of the above.
C
<Instruct>: Given the context 'Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection. ', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options.
<Options>: A: human immunodeficiency virus type 1 hiv 1 (aka human immunodeficiency virus 1) B: human immunodeficiency virus type 1 (kb-1 isolate) C: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus) D: None of the above.
A
<Instruct>: Given the context 'Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection. ', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options.
<Options>: A: human immunodeficiency virus (hiv (aka human immunodeficiency virus)) B: human immunodeficiency virus type 1 (kb-1 isolate) C: None of the above.
C
<Instruct>: Given the context 'Type 1 interferons (IFNs) induce the expression of the tripartite interaction motif (TRIM) family of E3 ligases, but the contribution of these antiviral factors to HIV pathogenesis is not completely understood.', select the correct biomedical concept corresponding to 'hiv'. Answer using one of the provided options.
<Options>: A: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus) B: aids virus (aka human immunodeficiency virus 2) C: hiv (aka human immunodeficiency virus 3) (aka human immunodeficiency virus 3) D: human immunodeficiency virus type 1 hiv-1 (aka human immunodeficiency virus 1) E: None of the above.
D
<Instruct>: Given the context 'We hypothesized that the increased expression of select type 1 IFN and TRIM isoforms is associated with a significantly lower likelihood of HIV-1 acquisition and viral control during primary HIV-1 infection.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options.
<Options>: A: aids virus (aka human immunodeficiency virus) B: human immunodeficiency virus type 1 (kb-1 isolate) C: human immunodeficiency virus type 1, hiv-1 (aka human immunodeficiency virus 1) D: None of the above.
C
<Instruct>: Given the context 'We hypothesized that the increased expression of select type 1 IFN and TRIM isoforms is associated with a significantly lower likelihood of HIV-1 acquisition and viral control during primary HIV-1 infection.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options.
<Options>: A: aids virus (aka human immunodeficiency virus) B: human immunodeficiency virus type-1 hiv-1 (aka human immunodeficiency virus 1) C: human immunodeficiency virus type 1 (kb-1 isolate) D: None of the above.
B
<Instruct>: Given the context 'We measured IFN-alpha, IFN-Beta, myxovirus resistance protein A (MxA), human TRIM5alpha (huTRIM5alpha), and TRIM22 mRNA levels in peripheral blood mononuclear cells (PBMCs) of high-risk, HIV-1-uninfected participants and HIV-1-positive study participants.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options.
<Options>: A: human (aka homo sapiens) B: pediculus humanus humanus (aka pediculus humanus corporis) C: human louse (aka pediculus humanus) D: homo (humans) (aka homo) E: cardium humanum (aka glossus humanus) F: None of the above.
A
<Instruct>: Given the context 'We measured IFN-alpha, IFN-Beta, myxovirus resistance protein A (MxA), human TRIM5alpha (huTRIM5alpha), and TRIM22 mRNA levels in peripheral blood mononuclear cells (PBMCs) of high-risk, HIV-1-uninfected participants and HIV-1-positive study participants.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options.
<Options>: A: human immunodeficiency virus (hiv (aka human immunodeficiency virus)) B: human immunodeficiency virus type 1 (kb-1 isolate) C: human immunodeficiency virus type 1 hiv1 (aka human immunodeficiency virus 1) D: None of the above.
C
<Instruct>: Given the context 'We measured IFN-alpha, IFN-Beta, myxovirus resistance protein A (MxA), human TRIM5alpha (huTRIM5alpha), and TRIM22 mRNA levels in peripheral blood mononuclear cells (PBMCs) of high-risk, HIV-1-uninfected participants and HIV-1-positive study participants.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options.
<Options>: A: human immunodeficiency virus 1 hiv-1 (aka human immunodeficiency virus 1) B: human immunodeficiency virus type 1 (kb-1 isolate) C: human immunodeficiency virus (hiv (aka human immunodeficiency virus)) D: None of the above.
A
<Instruct>: Given the context 'HIV-1-positive participants had higher levels of IFN-Beta (P = 0.0005), MxA (P = 0.007), and TRIM22 (P = 0.01) and lower levels of huTRIM5alpha (P &lt; 0.001) than did HIV-1-negative participants.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options.
<Options>: A: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus) B: hiv-1 (aka human immunodeficiency virus 1) C: human immunodeficiency virus type 1 (kb-1 isolate) D: None of the above.
B
<Instruct>: Given the context 'HIV-1-positive participants had higher levels of IFN-Beta (P = 0.0005), MxA (P = 0.007), and TRIM22 (P = 0.01) and lower levels of huTRIM5alpha (P &lt; 0.001) than did HIV-1-negative participants.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options.
<Options>: A: aids virus (aka human immunodeficiency virus) B: human immunodeficiency virus type 1 (kb-1 isolate) C: human immunodeficiency virus type 1, hiv-1 (aka human immunodeficiency virus 1) D: None of the above.
C
<Instruct>: Given the context 'In vitro studies revealed that HIV infection induced TRIM22 expression in PBMCs obtained from HIV-negative donors.', select the correct biomedical concept corresponding to 'hiv'. Answer using one of the provided options.
<Options>: A: aids virus (aka human immunodeficiency virus 2) B: hiv-1 (aka human immunodeficiency virus 1) C: hiv (aka human immunodeficiency virus 3) (aka human immunodeficiency virus 3) D: aids virus (aka human immunodeficiency virus) E: None of the above.
B
<Instruct>: Given the context 'In vitro studies revealed that HIV infection induced TRIM22 expression in PBMCs obtained from HIV-negative donors.', select the correct biomedical concept corresponding to 'hiv'. Answer using one of the provided options.
<Options>: A: human immunodeficiency virus (hiv (aka human immunodeficiency virus)) B: human immunodeficiency virus 3 (hiv (aka human immunodeficiency virus 3)) C: hiv-1 (aka human immunodeficiency virus 1) D: aids virus (aka human immunodeficiency virus 2) E: None of the above.
C
<Instruct>: Given the context 'In vitro studies revealed that HIV infection induced TRIM22 expression in PBMCs obtained from HIV-negative donors.', select the correct biomedical concept corresponding to 'hiv'. Answer using one of the provided options.
<Options>: A: aids virus (aka human immunodeficiency virus 2) B: human immunodeficiency virus 3 (hiv (aka human immunodeficiency virus 3)) C: aids virus (aka human immunodeficiency virus) D: None of the above.
D
<Instruct>: Given the context 'Stable TRIM22 knockdown resulted in increased HIV-1 particle release and replication in Jurkat reporter cells.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options.
<Options>: A: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus) B: human immunodeficiency virus type 1 (kb-1 isolate) C: human immunodeficiency virus type 1 (aka human immunodeficiency virus 1) D: None of the above.
C
<Instruct>: Given the context 'Interbacterial macromolecular transfer by the Campylobacter fetus subsp. venerealis type IV secretion system. ', select the correct biomedical concept corresponding to 'campylobacter fetus subsp. venerealis'. Answer using one of the provided options.
<Options>: A: campylobacter fetus subsp. venerealis bv. venerealis B: vibrio fetus (aka campylobacter fetus) C: campylobacter jejuni-like bacterium D: campylobacter fetus subsp. venerealis cfvi03/293 E: campylobacter fetus subsp. venerealis bv. intermedius F: None of the above.
B
<Instruct>: Given the context 'We report here the first demonstration of intra- and interspecies conjugative plasmid DNA transfer for Campylobacter fetus.', select the correct biomedical concept corresponding to 'campylobacter fetus'. Answer using one of the provided options.
<Options>: A: vibrio jejuni (aka campylobacter jejuni) B: campylobacter fetus (spirillum fetus) (aka campylobacter fetus) C: campylobacter D: campylobacter suis E: campylobacter vicugnae (campylobacter ovis) (aka campylobacter vicugnae) F: None of the above.
B
<Instruct>: Given the context 'Gene regions carried by a Campylobacter coli plasmid were identified that are sufficient for conjugative mobilization to Escherichia coli and C. fetus recipients.', select the correct biomedical concept corresponding to 'campylobacter coli'. Answer using one of the provided options.
<Options>: A: bacterium coli (aka escherichia coli) B: vibrio jejuni (aka campylobacter jejuni) C: campylobacter concisus D: campylobacter hyoilei (aka campylobacter coli) E: campylobacter F: None of the above.
D
<Instruct>: Given the context 'Gene regions carried by a Campylobacter coli plasmid were identified that are sufficient for conjugative mobilization to Escherichia coli and C. fetus recipients.', select the correct biomedical concept corresponding to 'escherichia coli'. Answer using one of the provided options.
<Options>: A: escherichia faecalis ('escherichia faecalis') (aka escherichia faecalis) B: escherichia C: escherichia freundii (aka citrobacter freundii) D: entamoeba coli E: bacterium coli commune (aka escherichia coli) F: None of the above.
E
<Instruct>: Given the context 'Gene regions carried by a Campylobacter coli plasmid were identified that are sufficient for conjugative mobilization to Escherichia coli and C. fetus recipients.', select the correct biomedical concept corresponding to 'c. fetus'. Answer using one of the provided options.
<Options>: A: campylobacter ovis (aka campylobacter vicugnae) B: chordifex abortivus (restio abortivus) (aka chordifex abortivus) C: cytauxzoon felis D: campylobacter fetus (spirillum fetus) (aka campylobacter fetus) E: afrocloetus F: None of the above.
D
<Instruct>: Given the context 'Efficient DNA transfer involves the virB9 and virD4 genes of the type IV bacterial secretion system encoded by a pathogenicity island of C. fetus subsp. venerealis.', select the correct biomedical concept corresponding to 'c. fetus subsp. venerealis'. Answer using one of the provided options.
<Options>: A: campylobacter fetus subsp. venerealis cfvb10 B: campylobacter fetus subsp. venerealis cfvi01/165 C: vibrio fetus (aka campylobacter fetus) D: campylobacter fetus subsp. venereus (aka campylobacter fetus subsp. venerealis) E: campylobacter fetus subsp. venerealis cfvi97/532 F: None of the above.
C
<Instruct>: Given the context 'Complementation of these phenotypes from expression constructions based on the promoter of the C. fetus surface antigen protein (sap) locus was temperature dependent, and a temperature regulation of the sap promoter was subsequently confirmed under laboratory conditions.', select the correct biomedical concept corresponding to 'c. fetus'. Answer using one of the provided options.
<Options>: A: cytauxzoon felis B: campylobacter ovis (aka campylobacter vicugnae) C: cichlidogyrus gallus D: cixius cunicularius (cicada cunicularius) (aka cixius cunicularius) E: campylobacter fetus (spirillum fetus) (aka campylobacter fetus) F: None of the above.
E
<Instruct>: Given the context 'Gene transfer was sensitive to surface or entry exclusion functions in potential recipient cells carrying IncPalpha plasmid RP4 implying functional relatedness to C. fetus proteins.', select the correct biomedical concept corresponding to 'c. fetus'. Answer using one of the provided options.
<Options>: A: cryptosporidium bovis B: cixius cunicularius (cicada cunicularius) (aka cixius cunicularius) C: cryptosporidium felis D: campylobacter fetus (spirillum fetus) (aka campylobacter fetus) E: cytauxzoon felis F: None of the above.
D
<Instruct>: Given the context 'The virB/virD4 locus is also known to be involved in bacterial invasion and killing of cultured human cells in vitro.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options.
<Options>: A: pediculus humanus corporis (pediculus humanus humanus) (aka pediculus humanus corporis) B: sphaeria humana (aka sordaria humana) C: gymnopleurus humanus D: human (aka homo sapiens) E: macrobiotus sapiens F: None of the above.
D
<Instruct>: Given the context 'The virB/virD4 locus is also known to be involved in bacterial invasion and killing of cultured human cells in vitro.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options.
<Options>: A: neanderthal man (aka homo sapiens neanderthalensis) B: human body louse (aka pediculus humanus corporis) C: carcharhinus humani D: pediculus humanus (human louse) (aka pediculus humanus) E: humans (aka homo) F: None of the above.
F
<Instruct>: Given the context 'Two putative effector proteins carrying an FIC domain conserved in a few bacterial type III and type IV secreted proteins of pathogens were analyzed for secretion by the C. fetus or heterologous conjugative systems.', select the correct biomedical concept corresponding to 'c. fetus'. Answer using one of the provided options.
<Options>: A: cryptorhynchus gravis (aka sternochetus gravis) B: cryptosporidium felis C: chorioptes ovis (aka chorioptes bovis) D: campylobacter fetus (spirillum fetus) (aka campylobacter fetus) E: chorizococcus F: None of the above.
D
<Instruct>: Given the context 'Serinicoccus profundi sp. nov., an actinomycete isolated from deep-sea sediment, and emended description of the genus Serinicoccus. ', select the correct biomedical concept corresponding to 'serinicoccus profundi sp. nov.'. Answer using one of the provided options.
<Options>: A: serinicoccus profundi B: serinicoccus C: oceanobacillus profundus D: serinicoccus sp. 13-12-5 E: streptomyces profundus F: None of the above.
A
<Instruct>: Given the context 'A Gram-reaction-positive bacterial strain of the genus Serinicoccus, designated MCCC 1A05965(T), was isolated from a deep-sea (5368 m) sediment of the Indian Ocean.', select the correct biomedical concept corresponding to 'mccc 1a05965'. Answer using one of the provided options.
<Options>: A: uncultured organism meddcm-oct-s12-c71 B: uncultured prochlorococcus marinus clone hot0m-5c8 C: uncultured organism meddcm-oct-s12-c54 D: uncultured archaeon meddcm-oct-s05-c10 E: uncultured organism meddcm-oct-s08-c100 F: None of the above.
F
<Instruct>: Given the context 'Comparison of 16S rRNA gene sequences revealed that the isolate shared 97.6 % sequence similarity with Serinicoccus marinus JC1078(T), the type strain of the only described species of the genus Serinicoccus.', select the correct biomedical concept corresponding to 'serinicoccus marinus'. Answer using one of the provided options.
<Options>: A: amphileptus marinus B: roseovarius marinus (aka pacificibacter marinus) C: serinicoccus marinus D: staphylinus marinus (aka micralymma marinum) E: gelatiniphilus marinus F: None of the above.
C
<Instruct>: Given the context 'Other characteristics of strain MCCC 1A05965(T) were consistent with those of the genus Serinicoccus.', select the correct biomedical concept corresponding to 'mccc 1a05965'. Answer using one of the provided options.
<Options>: A: uncultured organism meddcm-oct-s08-c51 B: uncultured organism meddcm-oct-s12-c54 C: uncultured organism meddcm-oct-s11-c1587 D: uncultured micrococcus mc5 E: pasteurella aerogenes mccm 01550 F: None of the above.
F
<Instruct>: Given the context 'Strain MCCC 1A05965(T)', select the correct biomedical concept corresponding to 'mccc 1a05965'. Answer using one of the provided options.
<Options>: A: uncultured organism meddcm-oct-s04-c100 B: uncultured organism meddcm-oct-s08-c51 C: uncultured micrococcus mc5 D: micrococcus sp. mccc 1a09815 E: pasteurella aerogenes mccm 01551 F: None of the above.
F
<Instruct>: Given the context '=CGMCC 4.5582(T)) is assigned as the type strain of a novel species, for which the name Serinicoccus profundi sp. nov. is proposed. ', select the correct biomedical concept corresponding to 'serinicoccus profundi sp. nov'. Answer using one of the provided options.
<Options>: A: streptomyces profundus B: serinicoccus hydrothermalis C: novosphingobium profundi D: serinicoccus profundi E: serinicoccus sediminis F: None of the above.
D
<Instruct>: Given the context 'High-titer autologous neutralizing antibody responses have been demonstrated during early subtype C human immunodeficiency virus type 1 (HIV-1) infection.', select the correct biomedical concept corresponding to 'human immunodeficiency virus type 1'. Answer using one of the provided options.
<Options>: A: human immunodeficiency virus type 1 (new york-5 isolate) B: human immunodeficiency virus 1 (human immunodeficiency virus type 1, hiv-1) (aka human immunodeficiency virus 1) C: human immunodeficiency virus (hiv (aka human immunodeficiency virus)) D: None of the above.
B
<Instruct>: Given the context 'High-titer autologous neutralizing antibody responses have been demonstrated during early subtype C human immunodeficiency virus type 1 (HIV-1) infection.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options.
<Options>: A: human immunodeficiency virus type 1 (kb-1 isolate) B: human immunodeficiency virus type i hiv-1 (aka human immunodeficiency virus 1) C: human immunodeficiency virus (hiv (aka human immunodeficiency virus)) D: None of the above.
B
<Instruct>: Given the context 'Poliovirus RNA is released from the capsid near a twofold symmetry axis. ', select the correct biomedical concept corresponding to 'poliovirus'. Answer using one of the provided options.
<Options>: A: murine poliovirus (aka theiler's encephalomyelitis virus) B: poliovirus (aka enterovirus c) C: pv1 (aka poliovirus 1) (aka poliovirus 1) D: p virus E: poliovirus serotype 3 (aka poliovirus 3) F: None of the above.
B
<Instruct>: Given the context 'Poliovirus RNA is released from the capsid near a twofold symmetry axis. ', select the correct biomedical concept corresponding to 'poliovirus'. Answer using one of the provided options.
<Options>: A: human poliovirus type 2 (aka poliovirus 2) B: unidentified poliovirus C: polio virus 1 (aka poliovirus 1) D: murine poliovirus (aka theiler's encephalomyelitis virus) E: p virus F: None of the above.
F
<Instruct>: Given the context 'After recognizing and binding to its host cell, poliovirus (like other nonenveloped viruses) faces the challenge of translocating its genome across a cellular membrane and into the cytoplasm.', select the correct biomedical concept corresponding to 'poliovirus'. Answer using one of the provided options.
<Options>: A: unidentified poliovirus B: poliovirus type 2 (aka poliovirus 2) C: polio virus 3 (aka poliovirus 3) D: poliovirus (aka enterovirus c) E: pv1 (aka poliovirus 1) (aka poliovirus 1) F: None of the above.
D
<Instruct>: Given the context 'To help to elucidate the mechanism of infection, we have used single-particle cryo-electron microscopy and tomography to reconstruct conformationally altered intermediates that are formed by the poliovirion at various stages of the poliovirus infection process.', select the correct biomedical concept corresponding to 'poliovirus'. Answer using one of the provided options.
<Options>: A: p virus B: unidentified poliovirus C: poliovirus 3 (human poliovirus type 3) (aka poliovirus 3) D: murine poliovirus (aka theiler's encephalomyelitis virus) E: poliovirus (aka enterovirus c) F: None of the above.
E
<Instruct>: Given the context 'Yeast-elicited cross-reactive antibodies to HIV Env glycans efficiently neutralize virions expressing exclusively high-mannose N-linked glycans. ', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options.
<Options>: A: saccharomyces ovalis (aka malassezia furfur) B: saccharomyces globosus (aka saccharomyces uvarum) C: saccharomyces marxianus (aka kluyveromyces marxianus) D: saccharomyces drosophilarum (aka kluyveromyces lactis) E: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces cerevisiae) F: None of the above.
E
<Instruct>: Given the context 'Yeast-elicited cross-reactive antibodies to HIV Env glycans efficiently neutralize virions expressing exclusively high-mannose N-linked glycans. ', select the correct biomedical concept corresponding to 'hiv'. Answer using one of the provided options.
<Options>: A: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus) B: aids virus (aka human immunodeficiency virus 2) C: human immunodeficiency virus-1 hiv-1 (aka human immunodeficiency virus 1) D: hiv (aka human immunodeficiency virus 3) (aka human immunodeficiency virus 3) E: None of the above.
A
<Instruct>: Given the context 'We have described a triple mutant Saccharomyces cerevisiae strain that expresses high-mannose glycoproteins that bind to 2G12.', select the correct biomedical concept corresponding to 'saccharomyces cerevisiae'. Answer using one of the provided options.
<Options>: A: saccharomyces paradoxus B: saccharomyces oviformis (aka saccharomyces cerevisiae) C: saccharomyces ovalis (aka malassezia furfur) D: saccharomyces rouxii (aka zygosaccharomyces rouxii) E: saccharomyces drosophilarum (aka kluyveromyces lactis) F: None of the above.
B
<Instruct>: Given the context 'When used to immunize rabbits, this yeast elicits antibodies that bind to gp120-associated glycans but fail to neutralize virus.', select the correct biomedical concept corresponding to 'rabbits'. Answer using one of the provided options.
<Options>: A: riverine rabbit (aka bunolagus monticularis) B: lepus saxatilis (scrub hare) (aka lepus saxatilis) C: lepus cuniculus (aka oryctolagus cuniculus) D: rabbits and hares (aka leporidae) E: marsh rabbit (aka sylvilagus palustris) F: None of the above.
C
<Instruct>: Given the context 'When used to immunize rabbits, this yeast elicits antibodies that bind to gp120-associated glycans but fail to neutralize virus.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options.
<Options>: A: saccharomyces marxianus (aka kluyveromyces marxianus) B: saccharomyces oviformis (aka saccharomyces cerevisiae) C: torulaspora lactis (aka kluyveromyces lactis) D: saccharomyces globosus (aka saccharomyces uvarum) E: saccharomyces fermentati (aka torulaspora delbrueckii) F: None of the above.
B
<Instruct>: Given the context 'Affinity purification of sera over columns conjugated with three 2G12-reactive yeast glycoproteins showed that these proteins could adsorb 80% of the antibodies that bind to gp120 glycans.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options.
<Options>: A: baker's yeast (aka saccharomyces cerevisiae) B: saccharomyces marxianus (aka kluyveromyces marxianus) C: saccharomyces rouxii (aka zygosaccharomyces rouxii) D: saccharomyces lactis (aka kluyveromyces lactis) E: saccharomyces albicans (aka candida albicans) F: None of the above.
A
<Instruct>: Given the context 'Combined, these data show that the triple mutant yeast strain elicits antibodies that bind to high-mannose glycans presented on the HIV envelope, but only when they are displayed in a manner not found on native Env trimers.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options.
<Options>: A: saccharomyces globosus (aka saccharomyces uvarum) B: saccharomyces albicans (aka candida albicans) C: saccharomyces rouxii (aka zygosaccharomyces rouxii) D: saccharomycodes E: mycoderma cerevisiae (aka saccharomyces cerevisiae) F: None of the above.
E
<Instruct>: Given the context 'Here, we report the sequencing of the small RNAs in rat cytomegalovirus (RCMV)-infected fibroblasts and persistently infected salivary glands.', select the correct biomedical concept corresponding to 'rat cytomegalovirus'. Answer using one of the provided options.
<Options>: A: mouse cytomegalovirus B: rodent herpesvirus C: murid betaherpesvirus 2 (rat cytomegalovirus) (aka murid betaherpesvirus 2) D: rat minute virus E: cytomegalovirus F: None of the above.
C
<Instruct>: Given the context 'Here, we report the sequencing of the small RNAs in rat cytomegalovirus (RCMV)-infected fibroblasts and persistently infected salivary glands.', select the correct biomedical concept corresponding to 'rat cytomegalovirus'. Answer using one of the provided options.
<Options>: A: rattus norvegicus adenovirus B: rat minute virus C: rattus rat parvovirus D: cynomys herpesvirus E: mus rat parvovirus F: None of the above.
F
<Instruct>: Given the context 'Here, we report the sequencing of the small RNAs in rat cytomegalovirus (RCMV)-infected fibroblasts and persistently infected salivary glands.', select the correct biomedical concept corresponding to 'rcmv'. Answer using one of the provided options.
<Options>: A: rat minute virus B: replication competent viruses C: cgrmv (aka cherry green ring mottle virus) D: red clover mottle virus (rcmv (aka red clover mottle virus)) E: carnation mottle virus (carmv) (aka carnation mottle virus) F: None of the above.
F
<Instruct>: Given the context 'The RCMV miRNAs are distributed across the viral genome on both the positive and negative strands, with clusters of miRNAs at a number of locations, including near viral genes r1 and r111.', select the correct biomedical concept corresponding to 'rcmv'. Answer using one of the provided options.
<Options>: A: catharanthus mosaic virus B: crmav (aka cherry rusty mottle associated virus) C: replication competent viruses D: cnrmv (aka cherry necrotic rusty mottle virus) E: rattus gemycircularvirus F: None of the above.
F
<Instruct>: Given the context 'The RCMV miRNAs have a genomic positional orientation similar to that of the miRNAs described for mouse cytomegalovirus, but they do not share any substantial sequence conservation.', select the correct biomedical concept corresponding to 'rcmv'. Answer using one of the provided options.
<Options>: A: carmel mito-like virus B: marr virus C: cgrmv (aka cherry green ring mottle virus) D: crv (aka cowbone ridge virus) (aka cowbone ridge virus) E: crmav (aka cherry rusty mottle associated virus) F: None of the above.
F
<Instruct>: Given the context 'The RCMV miRNAs have a genomic positional orientation similar to that of the miRNAs described for mouse cytomegalovirus, but they do not share any substantial sequence conservation.', select the correct biomedical concept corresponding to 'mouse cytomegalovirus'. Answer using one of the provided options.
<Options>: A: mouse thymic virus (aka murid herpesvirus 3) B: mouse cytomegalovirus C: murine parvovirus (aka minute virus of mice) D: mouse herpesvirus 68 (aka murid gammaherpesvirus 4) E: murine cytomegalovirus (mcmv) (aka murid betaherpesvirus 1) F: None of the above.
E
<Instruct>: Given the context 'Similar to other reported miRNAs, the RCMV miRNAs had considerable variation at their 3' and 5' ends.', select the correct biomedical concept corresponding to 'rcmv'. Answer using one of the provided options.
<Options>: A: ribgrass mosaic virus B: marr virus C: replication competent viruses D: rattus gemycircularvirus E: rat minute virus F: None of the above.
F
<Instruct>: Given the context 'We determined by real-time PCR that expression of the RCMV miRNA miR-r111.1-2 is highly expressed in the salivary glands and that miR-R87-1 is expressed in most tissues during the acute infection phase.', select the correct biomedical concept corresponding to 'rcmv'. Answer using one of the provided options.
<Options>: A: cabmv (aka cowpea aphid-borne mosaic virus) B: carmel mito-like virus C: crmav (aka cherry rusty mottle associated virus) D: rcmv (aka red clover mottle virus) (aka red clover mottle virus) E: rattus gemycircularvirus F: None of the above.
F
<Instruct>: Given the context 'Our study identified the miRNAs expressed by RCMV in vitro and in vivo and demonstrated that expression is tissue specific and associated with a stage of viral infection. ', select the correct biomedical concept corresponding to 'rcmv'. Answer using one of the provided options.
<Options>: A: crv (aka cowbone ridge virus) (aka cowbone ridge virus) B: carnation mottle virus (carmv) (aka carnation mottle virus) C: cabmv (aka cowpea aphid-borne mosaic virus) D: catharanthus mosaic virus E: cnrmv (aka cherry necrotic rusty mottle virus) F: None of the above.
F
<Instruct>: Given the context 'Furthermore, infection of mice with rJPVDeltaSH induced more TNF-alpha expression, indicating that SH plays a role in blocking TNF-alpha expression in vivo. ', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options.
<Options>: A: eastern european house mouse (aka mus musculus musculus) B: mus famulus (servant mouse) (aka mus famulus) C: mus terricolor (earth-colored mouse) (aka mus terricolor) D: house mouse (aka mus musculus) E: mus <genus> (mice (aka mus <genus>)) F: None of the above.
D
<Instruct>: Given the context 'Translational control of the abundance of cytoplasmic poly(A) binding protein in human cytomegalovirus-infected cells. ', select the correct biomedical concept corresponding to 'human cytomegalovirus'. Answer using one of the provided options.
<Options>: A: human gammaherpesvirus 4 (human herpesvirus 4 (epstein-barr virus)) (aka human gammaherpesvirus 4) B: rat cytomegalovirus (aka murid betaherpesvirus 2) C: human herpesvirus 5 (aka human betaherpesvirus 5) D: human herpesvirus 2 (aka human alphaherpesvirus 2) E: human herpesvirus 8 (aka human gammaherpesvirus 8) F: None of the above.
C
<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept corresponding to 'herpes simplex virus type 1'. Answer using one of the provided options.
<Options>: A: herpes simplexvirus B: human alphaherpesvirus 1 strain f (herpes simplex virus (type 1 / strain f)) (aka human alphaherpesvirus 1 strain f) C: herpes simplex virus ii (aka human alphaherpesvirus 2) D: human herpesvirus 1 (aka human alphaherpesvirus 1) E: human alphaherpesvirus 1 strain kos (herpes simplex virus (type 1 / strain kos)) (aka human alphaherpesvirus 1 strain kos) F: None of the above.
D
<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept corresponding to 'herpes simplex virus type 1'. Answer using one of the provided options.
<Options>: A: human alphaherpesvirus 1 strain kos (herpes simplex virus (type 1 / strain kos)) (aka human alphaherpesvirus 1 strain kos) B: human alphaherpesvirus 1 strain f (herpes simplex virus (type 1 / strain f)) (aka human alphaherpesvirus 1 strain f) C: herpes simplex virus (type 2) (aka human alphaherpesvirus 2) D: herpes simplexvirus E: None of the above.
E
<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept corresponding to 'kaposi's sarcoma herpesvirus'. Answer using one of the provided options.
<Options>: A: kaptombes virus B: hhv-3 (aka human alphaherpesvirus 3) C: kaposi's sarcoma herpesvirus (aka human gammaherpesvirus 8) D: phocid herpesvirus 1 (aka phocid alphaherpesvirus 1) E: human herpesvirus 7 (aka human betaherpesvirus 7) F: None of the above.
C
<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept corresponding to 'human cytomegalovirus'. Answer using one of the provided options.
<Options>: A: cytomegalovirus B: unidentified cytomegalovirus C: human gammaherpesvirus 4 (human herpesvirus 4 (epstein-barr virus)) (aka human gammaherpesvirus 4) D: human cytomegalovirus (aka human betaherpesvirus 5) E: murine cytomegalovirus (aka murid betaherpesvirus 1) F: None of the above.
D
<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept corresponding to 'hcmv'. Answer using one of the provided options.
<Options>: A: human herpesvirus 6b (aka human betaherpesvirus 6b) B: herpes virus b (aka macacine alphaherpesvirus 1) C: japanese cytomegalovirus D: porcine cytomegalovirus (aka suid betaherpesvirus 2) E: human cytomegalovirus (aka human betaherpesvirus 5) F: None of the above.
E
<Instruct>: Given the context 'Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP).', select the correct biomedical concept corresponding to 'hcmv'. Answer using one of the provided options.
<Options>: A: herpesvirus m (aka saimiriine alphaherpesvirus 1) B: human herpesvirus 8 (aka human gammaherpesvirus 8) C: human herpesvirus type 1 (aka human alphaherpesvirus 1) D: unidentified cytomegalovirus E: human herpesvirus 5 (aka human betaherpesvirus 5) F: None of the above.
E
<Instruct>: Given the context 'Here, we demonstrate that the increase in translation factor concentration was readily detected in an asynchronous population of HCMV-infected primary human fibroblasts, abolished by prior UV inactivation of virus, and genetically dependent upon viral immediate-early genes.', select the correct biomedical concept corresponding to 'hcmv'. Answer using one of the provided options.
<Options>: A: human cytomegalovirus (aka human betaherpesvirus 5) B: porcine cytomegalovirus (aka suid betaherpesvirus 2) C: murine cytomegalovirus (aka murid betaherpesvirus 1) D: herpes virus b (aka macacine alphaherpesvirus 1) E: human herpesvirus 8 (aka human gammaherpesvirus 8) F: None of the above.
A
<Instruct>: Given the context 'Here, we demonstrate that the increase in translation factor concentration was readily detected in an asynchronous population of HCMV-infected primary human fibroblasts, abolished by prior UV inactivation of virus, and genetically dependent upon viral immediate-early genes.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options.
<Options>: A: homo sapiens (human) (aka homo sapiens) B: macrobiotus sapiens C: human louse (aka pediculus humanus) D: gymnopleurus humanus E: carcharhinus humani F: None of the above.
A
<Instruct>: Given the context 'Strikingly, while increased mRNA steady-state levels accompanied the rise in eIF4E and eIF4G protein levels, the overall abundance of PABP mRNA, together with the half-life of the polypeptide it encodes, remained relatively unchanged by HCMV infection.', select the correct biomedical concept corresponding to 'hcmv'. Answer using one of the provided options.
<Options>: A: unidentified cytomegalovirus B: human herpesvirus 1 (aka human alphaherpesvirus 1) C: human betaherpesvirus 5 (human herpesvirus type 5) (aka human betaherpesvirus 5) D: japanese cytomegalovirus E: human herpesvirus 6b (aka human betaherpesvirus 6b) F: None of the above.
C
<Instruct>: Given the context 'Instead, HCMV-induced PABP accumulation resulted from new protein synthesis and was sensitive to the mTORC1-selective inhibitor rapamycin, which interferes with phosphorylation of the mTORC1 substrate p70 S6K and the translational repressor 4E-BP1.', select the correct biomedical concept corresponding to 'hcmv'. Answer using one of the provided options.
<Options>: A: japanese cytomegalovirus B: porcine cytomegalovirus (aka suid betaherpesvirus 2) C: human betaherpesvirus 5 (human herpesvirus type 5) (aka human betaherpesvirus 5) D: herpesvirus m (aka saimiriine alphaherpesvirus 1) E: human herpesvirus 8 (aka human gammaherpesvirus 8) F: None of the above.
C
<Instruct>: Given the context 'Finally, unlike the situation in alpha- or gammaherpesvirus-infected cells, where PABP is redistributed to nuclei, PABP accumulated in the cytoplasm of HCMV-infected cells.', select the correct biomedical concept corresponding to 'hcmv'. Answer using one of the provided options.
<Options>: A: cytomegalovirus B: human herpesvirus type 1 (aka human alphaherpesvirus 1) C: human herpesvirus 5 strain ad169 (human cytomegalovirus (strain ad169)) (aka human herpesvirus 5 strain ad169) D: human herpesvirus 5 (aka human betaherpesvirus 5) E: japanese cytomegalovirus F: None of the above.
D
<Instruct>: Given the context 'Thus, cytoplasmic PABP accumulation is translationally controlled in HCMV-infected cells via a mechanism requiring mTORC1-mediated inhibition of the cellular 4E-BP1 translational repressor. ', select the correct biomedical concept corresponding to 'hcmv'. Answer using one of the provided options.
<Options>: A: cytomegalovirus B: human herpesvirus 6b (aka human betaherpesvirus 6b) C: human herpesvirus 8 (aka human gammaherpesvirus 8) D: rodent herpesvirus E: human herpesvirus type 5 (aka human betaherpesvirus 5) F: None of the above.
E
<Instruct>: Given the context 'Thus, cytoplasmic PABP accumulation is translationally controlled in HCMV-infected cells via a mechanism requiring mTORC1-mediated inhibition of the cellular 4E-BP1 translational repressor. ', select the correct biomedical concept corresponding to 'hcmv'. Answer using one of the provided options.
<Options>: A: human herpesvirus 6b (aka human betaherpesvirus 6b) B: herpesvirus m (aka saimiriine alphaherpesvirus 1) C: japanese cytomegalovirus D: porcine cytomegalovirus (aka suid betaherpesvirus 2) E: human herpesvirus 8 (aka human gammaherpesvirus 8) F: None of the above.
F
<Instruct>: Given the context 'A new model of Epstein-Barr virus infection reveals an important role for earlylytic viral protein expression in the development of lymphomas. Epstein-Barr virus (EBV) infects cells in latent or lytic forms, but the roleof lytic infection in EBV-induced lymphomas is unclear.', select the correct biomedical concept corresponding to 'epstein-barr virus'. Answer using one of the provided options.
<Options>: A: rhesus epstein barr virus (aka macacine gammaherpesvirus 4) B: human gammaherpesvirus 4 (human herpesvirus 4 (epstein-barr virus)) (aka human gammaherpesvirus 4) C: epstein-barr virus (strain raji) (aka human herpesvirus 4 strain raji) D: bovine herpesvirus 2 (aka bovine alphaherpesvirus 2) E: epstein-barr virus-2 ebv-2 (aka human herpesvirus 4 type 2) F: None of the above.
B
<Instruct>: Given the context 'A new model of Epstein-Barr virus infection reveals an important role for earlylytic viral protein expression in the development of lymphomas. Epstein-Barr virus (EBV) infects cells in latent or lytic forms, but the roleof lytic infection in EBV-induced lymphomas is unclear.', select the correct biomedical concept corresponding to 'epstein-barr virus'. Answer using one of the provided options.
<Options>: A: rhesus epstein barr virus (aka macacine gammaherpesvirus 4) B: bohv-1 (aka bovine alphaherpesvirus 1) C: human herpesvirus 4 (epstein-barr virus) (aka human gammaherpesvirus 4) D: bovine herpesvirus 2 (aka bovine alphaherpesvirus 2) E: epstein-barr virus (strain raji) (aka human herpesvirus 4 strain raji) F: None of the above.
C
<Instruct>: Given the context 'A new model of Epstein-Barr virus infection reveals an important role for earlylytic viral protein expression in the development of lymphomas. Epstein-Barr virus (EBV) infects cells in latent or lytic forms, but the roleof lytic infection in EBV-induced lymphomas is unclear.', select the correct biomedical concept corresponding to 'ebv'. Answer using one of the provided options.
<Options>: A: epstein-barr virus ebv (aka human gammaherpesvirus 4) B: bat gammaherpesvirus C: beult virus D: bovine lymphotropic herpesvirus (blhv (aka bovine lymphotropic herpesvirus)) E: bohnovirus F: None of the above.
A