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<Instruct>: Given the context 'A new model of Epstein-Barr virus infection reveals an important role for earlylytic viral protein expression in the development of lymphomas.
Epstein-Barr virus (EBV) infects cells in latent or lytic forms, but the roleof lytic infection in EBV-induced lymphomas is unclear.', select the correct biomedical concept corresponding to 'ebv'. Answer using one of the provided options. | <Options>: A: bat gammaherpesvirus
B: beult virus
C: bohnovirus
D: epstein-barr virus type 1 ebv-1 (aka human herpesvirus 4 type 1)
E: epstein-barr virus (aka human gammaherpesvirus 4)
F: None of the above. | E |
<Instruct>: Given the context 'Here, we have used anew humanized mouse model, in which both human fetal CD34(+) hematopoietic stemcells and thymus/liver tissue are transplanted, to compare EBV pathogenesis andlymphoma formation following infection with a lytic replication-defectiveBZLF1-deleted (Z-KO) virus or a lytically active BZLF1(+) control.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mouse (aka mus <genus>)
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: eastern european house mouse (aka mus musculus musculus)
D: house mouse (aka mus musculus)
E: mus terricolor (earth-colored mouse) (aka mus terricolor)
F: None of the above. | D |
<Instruct>: Given the context 'Here, we have used anew humanized mouse model, in which both human fetal CD34(+) hematopoietic stemcells and thymus/liver tissue are transplanted, to compare EBV pathogenesis andlymphoma formation following infection with a lytic replication-defectiveBZLF1-deleted (Z-KO) virus or a lytically active BZLF1(+) control.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: hominidae (great apes) (aka hominidae)
B: pediculus humanus corporis (pediculus humanus humanus) (aka pediculus humanus corporis)
C: homo sapiens (human) (aka homo sapiens)
D: glossus humanus (cardium humanum) (aka glossus humanus)
E: gymnopleurus humanus
F: None of the above. | C |
<Instruct>: Given the context 'Here, we have used anew humanized mouse model, in which both human fetal CD34(+) hematopoietic stemcells and thymus/liver tissue are transplanted, to compare EBV pathogenesis andlymphoma formation following infection with a lytic replication-defectiveBZLF1-deleted (Z-KO) virus or a lytically active BZLF1(+) control.', select the correct biomedical concept corresponding to 'ebv'. Answer using one of the provided options. | <Options>: A: bohxovirus
B: bohxovirus oralis
C: ebv (aka human gammaherpesvirus 4) (aka human gammaherpesvirus 4)
D: bat betaherpesvirus
E: bovine torovirus
F: None of the above. | C |
<Instruct>: Given the context 'Specific immune responses against EBV-infected B cellswere generated in mice infected with either the control virus or the Z-KOvirus.', select the correct biomedical concept corresponding to 'ebv'. Answer using one of the provided options. | <Options>: A: burke virus
B: bohxovirus
C: epstein-barr virus type 1 ebv-1 (aka human herpesvirus 4 type 1)
D: epstein-barr virus (aka human gammaherpesvirus 4)
E: bat herpesvirus
F: None of the above. | D |
<Instruct>: Given the context 'Specific immune responses against EBV-infected B cellswere generated in mice infected with either the control virus or the Z-KOvirus.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
C: mus domesticus (aka mus musculus domesticus)
D: mus famulus (servant mouse) (aka mus famulus)
E: western wild mouse (aka mus spretus)
F: None of the above. | A |
<Instruct>: Given the context 'These results point to animportant role for lytic EBV infection in the development of B cell lymphomasin the context of an active host immune response.
', select the correct biomedical concept corresponding to 'ebv'. Answer using one of the provided options. | <Options>: A: bat herpesvirus
B: beult virus
C: epstein barr virus (aka human gammaherpesvirus 4)
D: gb virus
E: bat betaherpesvirus
F: None of the above. | C |
<Instruct>: Given the context 'These results point to animportant role for lytic EBV infection in the development of B cell lymphomasin the context of an active host immune response.
', select the correct biomedical concept corresponding to 'ebv'. Answer using one of the provided options. | <Options>: A: epstein-barr virus type 1 ebv-1 (aka human herpesvirus 4 type 1)
B: bovine lymphotropic herpesvirus (blhv (aka bovine lymphotropic herpesvirus))
C: bat gammaherpesvirus
D: bohwovirus
E: bohxovirus
F: None of the above. | F |
<Instruct>: Given the context 'Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: western wild mouse (aka mus spretus)
B: mus domesticus (aka mus musculus domesticus)
C: mus terricolor (earth-colored mouse) (aka mus terricolor)
D: eastern european house mouse (aka mus musculus musculus)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.
', select the correct biomedical concept corresponding to 'severe acute respiratory syndrome coronavirus'. Answer using one of the provided options. | <Options>: A: bat sars coronavirus (aka sars bat coronavirus)
B: sars-related bat coronavirus (aka bat sars-like coronavirus)
C: severe acute respiratory syndrome-related coronavirus (sars (aka severe acute respiratory syndrome-related coronavirus))
D: swine acute diarrhea syndrome coronavirus
E: sars2 (aka severe acute respiratory syndrome coronavirus 2)
F: None of the above. | C |
<Instruct>: Given the context 'Newly emerging viruses often circulate as a heterogeneous swarm in wild animal reservoirs prior to their emergence in humans, and their antigenic identities are often unknown until an outbreak situation.', select the correct biomedical concept corresponding to 'humans'. Answer using one of the provided options. | <Options>: A: gymnopleurus humanus
B: glossus humanus (cardium humanum) (aka glossus humanus)
C: pediculus humanus humanus (aka pediculus humanus corporis)
D: human (aka homo sapiens)
E: homo (humans) (aka homo)
F: None of the above. | D |
<Instruct>: Given the context 'The newly emerging severe acute respiratory syndrome coronavirus (SARS-CoV) and reemerging influenza virus cause disproportionate disease in the aged, who are also notoriously difficult to successfully vaccinate, likely due to immunosenescence.', select the correct biomedical concept corresponding to 'severe acute respiratory syndrome coronavirus'. Answer using one of the provided options. | <Options>: A: sars2 (aka severe acute respiratory syndrome coronavirus 2)
B: sars-cov (aka severe acute respiratory syndrome coronavirus)
C: sars coronavirus as
D: sars bat coronavirus (bat sars coronavirus) (aka sars bat coronavirus)
E: sars-related coronavirus (aka severe acute respiratory syndrome-related coronavirus)
F: None of the above. | E |
<Instruct>: Given the context 'The newly emerging severe acute respiratory syndrome coronavirus (SARS-CoV) and reemerging influenza virus cause disproportionate disease in the aged, who are also notoriously difficult to successfully vaccinate, likely due to immunosenescence.', select the correct biomedical concept corresponding to 'sars-cov'. Answer using one of the provided options. | <Options>: A: recombinant sars coronavirus
B: sars bat coronavirus (bat sars coronavirus) (aka sars bat coronavirus)
C: sars coronavirus as
D: sars-related coronavirus (aka severe acute respiratory syndrome-related coronavirus)
E: sars-cov (urbani strain) (aka sars coronavirus urbani)
F: None of the above. | D |
<Instruct>: Given the context 'From initial studies, we hypothesized that attenuated Venezuelan equine encephalitis virus (VEE) replicon particle (VRP) vaccine glycoproteins mediated vaccine failure in the aged.', select the correct biomedical concept corresponding to 'venezuelan equine encephalitis virus'. Answer using one of the provided options. | <Options>: A: veev (aka venezuelan equine encephalitis virus) (aka venezuelan equine encephalitis virus)
B: rio negro virus (venezuelan equine encephalitis virus vi) (aka rio negro virus)
C: venezuelan equine encephalitis virus iv (aka pixuna virus)
D: venezuelan equine encephalitis virus (strain trinidad donkey)
E: eastern equine encephalitis virus (eastern equine encephalomyelitis virus eeev) (aka eastern equine encephalitis virus)
F: None of the above. | A |
<Instruct>: Given the context 'From initial studies, we hypothesized that attenuated Venezuelan equine encephalitis virus (VEE) replicon particle (VRP) vaccine glycoproteins mediated vaccine failure in the aged.', select the correct biomedical concept corresponding to 'vee'. Answer using one of the provided options. | <Options>: A: veia
B: equine abortion virus (aka equid alphaherpesvirus 1)
C: equine encephalosis virus (equine encephalosis virus (eev)) (aka equine encephalosis virus)
D: vee (aka venezuelan equine encephalitis virus) (aka venezuelan equine encephalitis virus)
E: vebetovirus
F: None of the above. | D |
<Instruct>: Given the context 'We then compared the efficacies of vaccines bearing attenuated (VRP(3014)) or wild-type VEE glycoproteins (VRP(3000)) in young and aged mice within novel models of severe SARS-CoV pathogenesis.', select the correct biomedical concept corresponding to 'vee'. Answer using one of the provided options. | <Options>: A: bovine enterovirus (aka enterovirus e)
B: erve virus
C: vebetovirus
D: venezuelan equine encephalitis virus vee (aka venezuelan equine encephalitis virus)
E: equine encephalosis virus (eev) (aka equine encephalosis virus)
F: None of the above. | D |
<Instruct>: Given the context 'We then compared the efficacies of vaccines bearing attenuated (VRP(3014)) or wild-type VEE glycoproteins (VRP(3000)) in young and aged mice within novel models of severe SARS-CoV pathogenesis.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus californicus (aka peromyscus californicus)
B: mouse (aka mus <genus>)
C: mus molossinus (aka mus musculus molossinus)
D: mus terricolor (earth-colored mouse) (aka mus terricolor)
E: house mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'We then compared the efficacies of vaccines bearing attenuated (VRP(3014)) or wild-type VEE glycoproteins (VRP(3000)) in young and aged mice within novel models of severe SARS-CoV pathogenesis.', select the correct biomedical concept corresponding to 'sars-cov'. Answer using one of the provided options. | <Options>: A: sars-cov (aka severe acute respiratory syndrome coronavirus)
B: human coronavirus (strain sars) (aka severe acute respiratory syndrome-related coronavirus)
C: recombinant sars coronavirus
D: sars-related bat coronavirus (aka bat sars-like coronavirus)
E: sars coronavirus as
F: None of the above. | B |
<Instruct>: Given the context 'We then compared the efficacies of vaccines bearing attenuated (VRP(3014)) or wild-type VEE glycoproteins (VRP(3000)) in young and aged mice within novel models of severe SARS-CoV pathogenesis.', select the correct biomedical concept corresponding to 'sars-cov'. Answer using one of the provided options. | <Options>: A: sars-cov (urbani strain) (aka sars coronavirus urbani)
B: sars bat coronavirus (bat sars coronavirus) (aka sars bat coronavirus)
C: sars-related bat coronavirus (aka bat sars-like coronavirus)
D: sars coronavirus as
E: recombinant sars coronavirus
F: None of the above. | F |
<Instruct>: Given the context 'Aged animals receiving VRP(3000)-based vaccines were protected from SARS-CoV disease, while animals receiving the VRP(3014)-based vaccines were not.', select the correct biomedical concept corresponding to 'sars-cov'. Answer using one of the provided options. | <Options>: A: sarsrcov (aka severe acute respiratory syndrome-related coronavirus)
B: sars-cov (aka severe acute respiratory syndrome coronavirus)
C: sars-cov (urbani strain) (aka sars coronavirus urbani)
D: sars-related bat coronavirus (aka bat sars-like coronavirus)
E: recombinant sars coronavirus
F: None of the above. | A |
<Instruct>: Given the context 'Exploration into the mechanism(s) of successful vaccination in the immunosenescent should aid in the development of successful vaccine strategies for other viral diseases disproportionately affecting the elderly, like West Nile virus, influenza virus, norovirus, or other emerging viruses of the future.
', select the correct biomedical concept corresponding to 'west nile virus'. Answer using one of the provided options. | <Options>: A: northway virus
B: dengue virus
C: west nile virus 2 (west nile virus lineage 2) (aka west nile virus 2)
D: wnv (aka west nile virus) (aka west nile virus)
E: west nile virus lineage 1 (aka west nile virus 1)
F: None of the above. | D |
<Instruct>: Given the context 'Neutralizing antibody-resistant hepatitis C virus cell-to-cell transmission.
', select the correct biomedical concept corresponding to 'hepatitis c virus'. Answer using one of the provided options. | <Options>: A: hcv (aka hepacivirus hominis) (aka hepacivirus hominis)
B: hepatitis c viruses (aka hepacivirus)
C: human hepatitis a virus (hhav (aka human hepatitis a virus))
D: human hepatitis b virus hbv (aka hepatitis b virus)
E: hepatitis b virus type c (aka hepatitis b virus genotype c)
F: None of the above. | A |
<Instruct>: Given the context 'Hepatitis C virus (HCV) can initiate infection by cell-free particle and cell-cell contact-dependent transmission.', select the correct biomedical concept corresponding to 'hcv'. Answer using one of the provided options. | <Options>: A: hepatitis c viruses (aka hepacivirus)
B: human hepatitis c virus (aka hepacivirus hominis)
C: hcv-h (aka hepatitis c virus (isolate h))
D: human hepatitis circovirus
E: hcv-hun (aka hepatitis c virus (isolate hunan))
F: None of the above. | B |
<Instruct>: Given the context 'Cell-to-cell transmission is relatively resistant to anti-HCV glycoprotein monoclonal antibodies and polyclonal immunoglobulin isolated from infected individuals, providing an effective strategy for escaping host humoral immune responses.', select the correct biomedical concept corresponding to 'anti-hcv'. Answer using one of the provided options. | <Options>: A: hepatitis c virus 08.80.014
B: hepatitis b virus (subtype adr) (aka hepatitis b virus subtype adr)
C: antichiropus
D: hepatitis c virus hcv (aka hepacivirus hominis)
E: hcv-hun (aka hepatitis c virus (isolate hunan))
F: None of the above. | D |
<Instruct>: Given the context 'Chimeric viruses expressing the structural proteins representing the seven major HCV genotypes demonstrate neutralizing antibody-resistant cell-to-cell transmission.', select the correct biomedical concept corresponding to 'hcv'. Answer using one of the provided options. | <Options>: A: human hepatitis c virus (aka hepacivirus hominis)
B: human hepatitis b virus (aka hepatitis b virus)
C: hepatitis c virus (isolate japanese)
D: hepatovirus c
E: hepatitis c virus hcv-kf (hepatitis c virus (isolate hcv-kf)) (aka hepatitis c virus hcv-kf)
F: None of the above. | A |
<Instruct>: Given the context 'HCV entry is a multistep process involving numerous receptors.', select the correct biomedical concept corresponding to 'hcv'. Answer using one of the provided options. | <Options>: A: hepatitis c viruses (aka hepacivirus)
B: human hepatitis c virus hcv (aka hepacivirus hominis)
C: hepatitis c virus (isolate japanese)
D: human hepatitis circovirus
E: hhav (aka human hepatitis a virus) (aka human hepatitis a virus)
F: None of the above. | B |
<Instruct>: Given the context 'Reovirus infection or ectopic expression of outer capsid protein micro1 induces apoptosis independently of the cellular proapoptotic proteins Bax and Bak.
Mammalian orthoreoviruses induce apoptosis in vivo and in vitro; however, the specific mechanism by which apoptosis is induced is not fully understood.', select the correct biomedical concept corresponding to 'mammalian orthoreoviruses'. Answer using one of the provided options. | <Options>: A: mammalian orthoreovirus 4
B: orthonoravirus
C: avian orthoreovirus (avian reovirus) (aka avian orthoreovirus)
D: mammalian orthoreovirus
E: respirovirus
F: None of the above. | D |
<Instruct>: Given the context 'Additionally, mu1- or reovirus-induced release of cytochrome c occurred efficiently in Bax(-/-)Bak(-/-) mouse embryonic fibroblasts (MEFs).', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: western european house mouse (aka mus musculus domesticus)
B: western wild mouse (aka mus spretus)
C: mus terricolor (earth-colored mouse) (aka mus terricolor)
D: mouse (aka mus musculus)
E: mice (aka mus <genus>) (aka mus <genus>)
F: None of the above. | D |
<Instruct>: Given the context 'Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff.
Chikungunya virus (CHIKV) is an arthritogenic mosquito-transmitted alphavirus that is undergoing reemergence in areas around the Indian Ocean.', select the correct biomedical concept corresponding to 'chikungunya virus'. Answer using one of the provided options. | <Options>: A: chikungunya virus strain nagpur
B: chikungunya virus
C: chiba virus
D: chize virus
E: chikungunya virus strain senegal 37997
F: None of the above. | B |
<Instruct>: Given the context 'Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff.
Chikungunya virus (CHIKV) is an arthritogenic mosquito-transmitted alphavirus that is undergoing reemergence in areas around the Indian Ocean.', select the correct biomedical concept corresponding to 'chikungunya virus'. Answer using one of the provided options. | <Options>: A: chijiahe virus
B: chibugado virus
C: chikungunya virus strain nagpur
D: crimean-congo hemorrhagic virus (aka orthonairovirus haemorrhagiae)
E: chuzan virus
F: None of the above. | F |
<Instruct>: Given the context 'Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff.
Chikungunya virus (CHIKV) is an arthritogenic mosquito-transmitted alphavirus that is undergoing reemergence in areas around the Indian Ocean.', select the correct biomedical concept corresponding to 'chikungunya virus'. Answer using one of the provided options. | <Options>: A: chiqui virus
B: chikungunya virus strain senegal 37997
C: chivirus chi (salmonella virus chi) (aka chivirus chi)
D: hongshan virus
E: chikungunya virus
F: None of the above. | E |
<Instruct>: Given the context 'Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoff.
Chikungunya virus (CHIKV) is an arthritogenic mosquito-transmitted alphavirus that is undergoing reemergence in areas around the Indian Ocean.', select the correct biomedical concept corresponding to 'chikv'. Answer using one of the provided options. | <Options>: A: chiba virus
B: chikungunya virus
C: chibugado virus
D: chikungunya virus strain nagpur
E: king virus
F: None of the above. | B |
<Instruct>: Given the context 'Despite the current and potential danger posed by this virus, we know surprisingly little about the induction and evasion of CHIKV-associated antiviral immune responses.', select the correct biomedical concept corresponding to 'chikv'. Answer using one of the provided options. | <Options>: A: chijiahe virus
B: dengue virus
C: crimean-congo haemorrhagic fever virus (aka orthonairovirus haemorrhagiae)
D: chibugado virus
E: chikungunya virus
F: None of the above. | E |
<Instruct>: Given the context 'With this in mind we investigated innate immune reactions to CHIKV in human fibroblasts, a demonstrable in vivo target of virus replication and spread.', select the correct biomedical concept corresponding to 'chikv'. Answer using one of the provided options. | <Options>: A: chikungunya virus
B: canya virus
C: chilibre virus
D: culex japonicus (aka aedes japonicus)
E: crimean-congo haemorrhagic fever virus (aka orthonairovirus haemorrhagiae)
F: None of the above. | A |
<Instruct>: Given the context 'With this in mind we investigated innate immune reactions to CHIKV in human fibroblasts, a demonstrable in vivo target of virus replication and spread.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: human body louse (aka pediculus humanus corporis)
B: sphaeria humana (aka sordaria humana)
C: human (aka homo sapiens)
D: hominidae (great apes) (aka hominidae)
E: glossus humanus (cardium humanum) (aka glossus humanus)
F: None of the above. | C |
<Instruct>: Given the context 'We show that CHIKV infection leads to activation of the transcription factor interferon regulatory factor 3 (IRF3) and subsequent transcription of IRF3-dependent antiviral genes, including beta interferon (IFN-Beta).', select the correct biomedical concept corresponding to 'chikv'. Answer using one of the provided options. | <Options>: A: chiba virus
B: chikungunya virus
C: chibugado virus
D: chize virus
E: king virus
F: None of the above. | B |
<Instruct>: Given the context 'We further demonstrate that translation of cellular (but not viral) genes is blocked during infection and that although CHIKV is found to trigger inactivation of the translational molecule eukaryotic initiation factor subunit 2alpha by way of the double-stranded RNA sensor protein kinase R, this response is not required for the block to protein synthesis.', select the correct biomedical concept corresponding to 'chikv'. Answer using one of the provided options. | <Options>: A: chize virus
B: hunchun nairovirus
C: chibugado virus
D: chiba virus
E: chikungunya virus
F: None of the above. | E |
<Instruct>: Given the context 'Furthermore, overall diminution of cellular RNA synthesis is also observed in the presence of CHIKV and transcription of IRF3-dependent antiviral genes appears specifically blocked late in infection.', select the correct biomedical concept corresponding to 'chikv'. Answer using one of the provided options. | <Options>: A: hunchun nairovirus
B: chikungunya virus
C: culex japonicus (aka aedes japonicus)
D: king virus
E: karelian fever virus
F: None of the above. | B |
<Instruct>: Given the context 'We hypothesize that the observed absence of IFN-Beta and antiviral proteins during infection results from an evasion mechanism exhibited by CHIKV that is dependent on widespread shutoff of cellular protein synthesis and a targeted block to late synthesis of antiviral mRNA transcripts.
', select the correct biomedical concept corresponding to 'chikv'. Answer using one of the provided options. | <Options>: A: canya virus
B: oya virus
C: chikungunya virus
D: culex japonicus (aka aedes japonicus)
E: chijiahe virus
F: None of the above. | C |
<Instruct>: Given the context 'Dominant inhibition of Akt/protein kinase B signaling by the matrix protein of a negative-strand RNA virus.
Vesicular stomatitis virus (VSV) is a rhabdovirus that alters host nuclear and cytoplasmic function upon infection.', select the correct biomedical concept corresponding to 'vesicular stomatitis virus'. Answer using one of the provided options. | <Options>: A: vesicular stomatitis indiana virus (strain 94gub central america)
B: vesicular stomatitis alagoas virus (vsav (aka vesicular stomatitis alagoas virus))
C: vesicular stomatitis indiana virus (strain 85clb south america)
D: vesicular stomatitis virus (serotype new jersey / strain ogden)
E: vesicular stomatitis virus vsv (aka vesicular stomatitis virus)
F: None of the above. | E |
<Instruct>: Given the context 'Dominant inhibition of Akt/protein kinase B signaling by the matrix protein of a negative-strand RNA virus.
Vesicular stomatitis virus (VSV) is a rhabdovirus that alters host nuclear and cytoplasmic function upon infection.', select the correct biomedical concept corresponding to 'vesicular stomatitis virus'. Answer using one of the provided options. | <Options>: A: vesicular stomatitis new jersey virus (vsnjv) (aka vesicular stomatitis new jersey virus)
B: vesicular stomatitis indiana virus (strain 85clb south america)
C: vesicular stomatitis indiana virus (vsiv (aka vesicular stomatitis indiana virus))
D: swine vesicular exanthema virus (aka vesicular exanthema of swine virus)
E: vesicular stomatitis virus (serotype new jersey / strain ogden)
F: None of the above. | F |
<Instruct>: Given the context 'Dominant inhibition of Akt/protein kinase B signaling by the matrix protein of a negative-strand RNA virus.
Vesicular stomatitis virus (VSV) is a rhabdovirus that alters host nuclear and cytoplasmic function upon infection.', select the correct biomedical concept corresponding to 'vsv'. Answer using one of the provided options. | <Options>: A: swinepox virus
B: vesicular stomatitis virus (serotype new jersey / strain missouri)
C: vesicular stomatitis indiana virus (strain 98coe north america)
D: south river virus (sorv (aka south river virus))
E: vesicular stomatitis virus vsv (aka vesicular stomatitis virus)
F: None of the above. | E |
<Instruct>: Given the context 'We have investigated the effect of VSV infection on cellular signaling through the phosphatidylinositol-3 kinase (PI3k)/Akt signaling pathway.', select the correct biomedical concept corresponding to 'vsv'. Answer using one of the provided options. | <Options>: A: vesicular stomatitis indiana virus (strain 94gub central america)
B: avisivirus
C: vesicular stomatitis alagoas virus (vsav (aka vesicular stomatitis alagoas virus))
D: swine vesicular disease virus (strain h/3 '76)
E: vesicular stomatitis virus (vesicular stomatitis virus, vsv) (aka vesicular stomatitis virus)
F: None of the above. | E |
<Instruct>: Given the context 'Akt phosphorylation at both threonine 308 (Thr308) and serine 473 (Ser473) was inhibited in cells infected with VSV.', select the correct biomedical concept corresponding to 'vsv'. Answer using one of the provided options. | <Options>: A: vesicular stomatitis virus (vesicular stomatitis virus, vsv) (aka vesicular stomatitis virus)
B: swinepox virus
C: vesicular stomatitis virus (serotype new jersey / strain missouri)
D: gran virus
E: swine vesicular disease virus
F: None of the above. | A |
<Instruct>: Given the context 'These data illustrate that VSV utilizes a novel mechanism to alter this central player in cell signaling and oncogenesis.', select the correct biomedical concept corresponding to 'vsv'. Answer using one of the provided options. | <Options>: A: swinepox virus
B: swine vesicular disease virus (strain ukg/27/72)
C: vesicular stomatitis virus vsv (aka vesicular stomatitis virus)
D: vsav (aka vesicular stomatitis alagoas virus) (aka vesicular stomatitis alagoas virus)
E: sunguru virus
F: None of the above. | C |
<Instruct>: Given the context 'It also suggests an inside-out model of signal transduction where VSV interruption of nuclear events has a rapid and significant effect on membrane signaling events.
', select the correct biomedical concept corresponding to 'vsv'. Answer using one of the provided options. | <Options>: A: swine vesicular disease virus (strain h/3 '76)
B: sorv (aka south river virus) (aka south river virus)
C: avisivirus
D: vesicular stomatitis indiana virus (strain 94gub central america)
E: vesicular stomatitis virus, vsv (aka vesicular stomatitis virus)
F: None of the above. | E |
<Instruct>: Given the context 'Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu.
', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus 1 hiv-1 (aka human immunodeficiency virus 1)
B: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus)
C: human immunodeficiency virus type 1 (kb-1 isolate)
D: None of the above. | A |
<Instruct>: Given the context 'The HIV-1 protein Vpu counteracts the antiviral activity of the innate restriction factor BST-2/tetherin by a mechanism that partly depends on its interaction with Beta-TrCP, a substrate adaptor for an SCF (Skp-Cullin 1-F box) E3 ubiquitin ligase complex.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: human immunodeficiency virus hiv-1 (aka human immunodeficiency virus 1)
C: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus)
D: None of the above. | B |
<Instruct>: Given the context 'Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis.
Varicella-zoster virus (VZV) is a neurotropic alphaherpesvirus.', select the correct biomedical concept corresponding to 'varicella-zoster virus'. Answer using one of the provided options. | <Options>: A: small pox virus (aka variola virus)
B: varicellaria
C: variola
D: horsepox virus
E: human alphaherpesvirus 3 (vzv (aka human alphaherpesvirus 3))
F: None of the above. | E |
<Instruct>: Given the context 'Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis.
Varicella-zoster virus (VZV) is a neurotropic alphaherpesvirus.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo sapiens (human) (aka homo sapiens)
B: carcharhinus humani
C: macrobiotus sapiens
D: human body louse (aka pediculus humanus corporis)
E: human louse (aka pediculus humanus)
F: None of the above. | A |
<Instruct>: Given the context 'Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis.
Varicella-zoster virus (VZV) is a neurotropic alphaherpesvirus.', select the correct biomedical concept corresponding to 'varicella-zoster virus'. Answer using one of the provided options. | <Options>: A: horsepox virus
B: swinepox virus
C: vaccinia virus vv (aka vaccinia virus)
D: varicella zoster virus vzv (aka human alphaherpesvirus 3)
E: variola
F: None of the above. | D |
<Instruct>: Given the context 'Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis.
Varicella-zoster virus (VZV) is a neurotropic alphaherpesvirus.', select the correct biomedical concept corresponding to 'varicella-zoster virus'. Answer using one of the provided options. | <Options>: A: horsepox virus
B: swinepox virus
C: vaccinia virus vv (aka vaccinia virus)
D: simian varicella virus (aka cercopithecine alphaherpesvirus 9)
E: smallpox virus (aka variola virus)
F: None of the above. | F |
<Instruct>: Given the context 'Varicella-zoster virus glycoprotein E is a critical determinant of virulence in the SCID mouse-human model of neuropathogenesis.
Varicella-zoster virus (VZV) is a neurotropic alphaherpesvirus.', select the correct biomedical concept corresponding to 'vzv'. Answer using one of the provided options. | <Options>: A: varicella-zoster virus (strain dumas) (aka human herpesvirus 3 strain dumas)
B: varicella-zoster virus vzv (aka human alphaherpesvirus 3)
C: simian varicella virus (aka cercopithecine alphaherpesvirus 9)
D: smallpox virus (aka variola virus)
E: zebra herpesvirus
F: None of the above. | B |
<Instruct>: Given the context 'VZV infection of human dorsal root ganglion (DRG) xenografts in immunodeficient mice models the infection of sensory ganglia.', select the correct biomedical concept corresponding to 'vzv'. Answer using one of the provided options. | <Options>: A: varicella-zoster virus (strain dumas) (aka human herpesvirus 3 strain dumas)
B: human herpesvirus 3 vzv-32
C: smallpox (aka variola virus)
D: gallid herpesvirus
E: human alphaherpesvirus 3 (vzv (aka human alphaherpesvirus 3))
F: None of the above. | E |
<Instruct>: Given the context 'VZV infection of human dorsal root ganglion (DRG) xenografts in immunodeficient mice models the infection of sensory ganglia.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: sphaeria humana (aka sordaria humana)
B: human louse (aka pediculus humanus)
C: glossus humanus (cardium humanum) (aka glossus humanus)
D: human body louse (aka pediculus humanus corporis)
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | E |
<Instruct>: Given the context 'We examined DRG infection with recombinant VZV (recombinant Oka [rOka]) and the following gE mutants: gEDelta27-90, gEDeltaCys, gE-AYRV, and gE-SSTT.', select the correct biomedical concept corresponding to 'vzv'. Answer using one of the provided options. | <Options>: A: varicella-zoster virus (strain dumas) (aka human herpesvirus 3 strain dumas)
B: gallid herpesvirus
C: vzv (aka human alphaherpesvirus 3) (aka human alphaherpesvirus 3)
D: variola
E: herpesvirus pan (aka panine gammaherpesvirus 1)
F: None of the above. | C |
<Instruct>: Given the context 'Since neural cells express IDE, the gE/IDE interaction was dispensable for VZV neurotropism.', select the correct biomedical concept corresponding to 'vzv'. Answer using one of the provided options. | <Options>: A: zebra herpesvirus
B: herpesvirus pan (aka panine gammaherpesvirus 1)
C: human herpesvirus 3 strain dumas (varicella-zoster virus (strain dumas)) (aka human herpesvirus 3 strain dumas)
D: variola
E: varicellaria
F: None of the above. | F |
<Instruct>: Given the context 'These experiments suggest that the gE interaction with cellular IDE, gE targeting to TGN sites of virion envelopment, and phosphorylation at SSTT are dispensable for VZV DRG infection, whereas the gE/gI interaction is critical for VZV neurovirulence.
', select the correct biomedical concept corresponding to 'vzv'. Answer using one of the provided options. | <Options>: A: rabbitpox virus
B: smallpox virus (aka variola virus)
C: human orf virus
D: gallid herpesvirus
E: variola
F: None of the above. | F |
<Instruct>: Given the context 'Domain structure of Lassa virus L protein.
', select the correct biomedical concept corresponding to 'lassa virus'. Answer using one of the provided options. | <Options>: A: lassa virus (aka mammarenavirus lassaense)
B: swinepox virus
C: swine pneumovirus
D: porcine orthorubulavirus (aka orthorubulavirus suis)
E: swine influenza virus
F: None of the above. | A |
<Instruct>: Given the context 'This study aimed at providing evidence for the domain structure of L protein by combining bioinformatics with a stepwise mutagenesis approach using the Lassa virus minireplicon system.', select the correct biomedical concept corresponding to 'lassa virus'. Answer using one of the provided options. | <Options>: A: swine fever virus (aka classical swine fever virus)
B: lassa virus (aka mammarenavirus lassaense)
C: little sussex virus
D: swinepox virus
E: lasallevirus
F: None of the above. | B |
<Instruct>: Given the context 'Insertion of 5 or 10 amino acid residues was tolerated at seven sites (S407, G446, G467, G774, G939, S1952, and V2074 in Lassa virus AV).', select the correct biomedical concept corresponding to 'lassa virus av'. Answer using one of the provided options. | <Options>: A: little sussex virus
B: sierra nevada virus
C: swine orthopneumovirus
D: gill-associated virus
E: lassa virus (aka mammarenavirus lassaense)
F: None of the above. | E |
<Instruct>: Given the context 'In conclusion, this study demonstrates two interdomain linkers in Lassa virus L protein, at G467 and G939, suggesting that L protein is composed of at least three structural domains spanning residues 1 to 467, 467 to 939, and 939 to 2220.', select the correct biomedical concept corresponding to 'lassa virus'. Answer using one of the provided options. | <Options>: A: swine fever virus (aka classical swine fever virus)
B: landiras virus
C: lassa virus (aka mammarenavirus lassaense)
D: orthorubulavirus suis (porcine orthorubulavirus) (aka orthorubulavirus suis)
E: swine pneumovirus
F: None of the above. | C |
<Instruct>: Given the context 'In conclusion, this study demonstrates two interdomain linkers in Lassa virus L protein, at G467 and G939, suggesting that L protein is composed of at least three structural domains spanning residues 1 to 467, 467 to 939, and 939 to 2220.', select the correct biomedical concept corresponding to 'lassa virus'. Answer using one of the provided options. | <Options>: A: little sussex virus
B: swine pneumovirus
C: landiras virus
D: lasigmu virus
E: swine influenza virus
F: None of the above. | F |
<Instruct>: Given the context 'Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization.
Human immunodeficiency virus type 1 (HIV-1) infection is dependent on the proper disassembly of the viral capsid, or "uncoating," in target cells.', select the correct biomedical concept corresponding to 'human immunodeficiency virus type 1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus type 1 hiv-1 (aka human immunodeficiency virus 1)
B: human immunodeficiency virus type 1 (new york-5 isolate)
C: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
D: None of the above. | A |
<Instruct>: Given the context 'Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization.
Human immunodeficiency virus type 1 (HIV-1) infection is dependent on the proper disassembly of the viral capsid, or "uncoating," in target cells.', select the correct biomedical concept corresponding to 'human immunodeficiency virus type 1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus type-1 hiv-1 (aka human immunodeficiency virus 1)
B: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
C: human immunodeficiency virus type 1 (new york-5 isolate)
D: None of the above. | A |
<Instruct>: Given the context 'Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization.
Human immunodeficiency virus type 1 (HIV-1) infection is dependent on the proper disassembly of the viral capsid, or "uncoating," in target cells.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: aids virus (aka human immunodeficiency virus)
B: hiv (aka human immunodeficiency virus 1) (aka human immunodeficiency virus 1)
C: human immunodeficiency virus type 1 (kb-1 isolate)
D: None of the above. | B |
<Instruct>: Given the context 'The HIV-1 capsid consists of a conical multimeric complex of the viral capsid protein (CA) arranged in a hexagonal lattice.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
B: human immunodeficiency virus type i hiv-1 (aka human immunodeficiency virus 1)
C: human immunodeficiency virus type 1 (kb-1 isolate)
D: None of the above. | B |
<Instruct>: Given the context 'We describe here the mechanism of action of a small molecule HIV-1 inhibitor, PF-3450074 (PF74), which targets CA.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: human immunodeficiency virus hiv-1 (aka human immunodeficiency virus 1)
C: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
D: None of the above. | B |
<Instruct>: Given the context 'PF74 acts at an early stage of HIV-1 infection and inhibits reverse transcription in target cells.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: aids virus (aka human immunodeficiency virus)
C: hiv-1 (aka human immunodeficiency virus 1)
D: None of the above. | C |
<Instruct>: Given the context 'We show that PF74 binds specifically to HIV-1 particles, and substitutions in CA that confer resistance to the compound prevent binding.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
C: hiv (aka human immunodeficiency virus 1) (aka human immunodeficiency virus 1)
D: None of the above. | C |
<Instruct>: Given the context 'A single point mutation in CA that stabilizes the HIV-1 core also conferred strong resistance to the virus without inhibiting compound binding.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: aids virus (aka human immunodeficiency virus)
B: human immunodeficiency virus type 1 (kb-1 isolate)
C: hiv1 (aka human immunodeficiency virus 1) (aka human immunodeficiency virus 1)
D: None of the above. | C |
<Instruct>: Given the context 'Treatment of HIV-1 particles or purified cores with PF74 destabilized the viral capsid in vitro.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus type 1 (aka human immunodeficiency virus 1)
B: human immunodeficiency virus type 1 (kb-1 isolate)
C: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
D: None of the above. | A |
<Instruct>: Given the context 'Furthermore, the compound induced the rapid dissolution of the HIV-1 capsid in target cells.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
C: human immunodeficiency virus type 1 hiv 1 (aka human immunodeficiency virus 1)
D: None of the above. | C |
<Instruct>: Given the context 'Furthermore, the compound induced the rapid dissolution of the HIV-1 capsid in target cells.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: hiv (aka human immunodeficiency virus) (aka human immunodeficiency virus)
B: human immunodeficiency virus type 1 (kb-1 isolate)
C: None of the above. | C |
<Instruct>: Given the context 'PF74 antiviral activity was promoted by binding of the host protein cyclophilin A to the HIV-1 capsid, and PF74 and cyclosporine exhibited mutual antagonism.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: human immunodeficiency virus type 1 (aka human immunodeficiency virus 1)
C: aids virus (aka human immunodeficiency virus)
D: None of the above. | B |
<Instruct>: Given the context 'Our data suggest that PF74 triggers premature HIV-1 uncoating in target cells, thereby mimicking the activity of the retrovirus restriction factor TRIM5alpha.', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: human immunodeficiency virus type 1 (kb-1 isolate)
B: human immunodeficiency virus (hiv (aka human immunodeficiency virus))
C: human immunodeficiency virus 1 hiv-1 (aka human immunodeficiency virus 1)
D: None of the above. | C |
<Instruct>: Given the context 'This study highlights uncoating as a step in the HIV-1 life cycle that is susceptible to small molecule intervention.
', select the correct biomedical concept corresponding to 'hiv-1'. Answer using one of the provided options. | <Options>: A: lav-1 (aka human immunodeficiency virus 1)
B: human immunodeficiency virus type 1 (kb-1 isolate)
C: aids virus (aka human immunodeficiency virus)
D: None of the above. | A |
<Instruct>: Given the context 'Mice lacking both B7.1 and B7.2 showed reduced early expansion of CMV-specific CD4 T cells, consequently allowing for enhanced levels of persistent virus replication.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus californicus (aka peromyscus californicus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mus molossinus (aka mus musculus molossinus)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Novel F141L pre-S2 mutation in hepatitis B virus increases the risk of hepatocellular carcinoma in patients with chronic genotype C infections.
', select the correct biomedical concept corresponding to 'hepatitis b virus'. Answer using one of the provided options. | <Options>: A: duck hepatitis b virus (dhbv (aka duck hepatitis b virus))
B: hepatitis b virus (hbv) (aka hepatitis b virus)
C: hepatovirus b
D: hepatitis b virus (subtype ayw) (aka hepatitis b virus subtype ayw)
E: horseshoe bat hepatitis b virus (hbhbv) (aka horseshoe bat hepatitis b virus)
F: None of the above. | B |
<Instruct>: Given the context 'Several lines of evidence have suggested that some naturally occurring mutations of hepatitis B virus (HBV) play a critical role in hepatocellular carcinoma (HCC).', select the correct biomedical concept corresponding to 'hepatitis b virus'. Answer using one of the provided options. | <Options>: A: hepatitis b virus hbv (aka hepatitis b virus)
B: hepatitis b virus 2
C: horseshoe bat hepatitis b virus (hbhbv) (aka horseshoe bat hepatitis b virus)
D: hepatitis a virus (aka hepatovirus a)
E: gb virus-b (hepatitis gb virus b) (aka gb virus-b)
F: None of the above. | A |
<Instruct>: Given the context 'Several lines of evidence have suggested that some naturally occurring mutations of hepatitis B virus (HBV) play a critical role in hepatocellular carcinoma (HCC).', select the correct biomedical concept corresponding to 'hbv'. Answer using one of the provided options. | <Options>: A: hbv (aka hepatitis b virus) (aka hepatitis b virus)
B: non-human hbv
C: horseshoe bat hepatitis b virus (hbhbv) (aka horseshoe bat hepatitis b virus)
D: hepatitis b virus genotype b (hbv genotype b) (aka hepatitis b virus genotype b)
E: hepatitis b-type viruses (aka hepadnaviridae)
F: None of the above. | A |
<Instruct>: Given the context 'Poliovirus-mediated disruption of cytoplasmic processing bodies.
', select the correct biomedical concept corresponding to 'poliovirus'. Answer using one of the provided options. | <Options>: A: pv1 (aka poliovirus 1) (aka poliovirus 1)
B: p virus
C: poliovirus (aka enterovirus c)
D: unidentified poliovirus
E: poliovirus 2 (human poliovirus type 2) (aka poliovirus 2)
F: None of the above. | C |
<Instruct>: Given the context 'Poliovirus (PV) is a plus-strand RNA virus containing a genome that is a functional mRNA; thus, we investigated if PV antagonizes the processes that lead to formation of these structures.', select the correct biomedical concept corresponding to 'poliovirus'. Answer using one of the provided options. | <Options>: A: murine poliovirus (aka theiler's encephalomyelitis virus)
B: pv1 (aka poliovirus 1) (aka poliovirus 1)
C: human poliovirus 2 (aka poliovirus 2)
D: poliovirus (aka enterovirus c)
E: unidentified poliovirus
F: None of the above. | D |
<Instruct>: Given the context 'Poliovirus (PV) is a plus-strand RNA virus containing a genome that is a functional mRNA; thus, we investigated if PV antagonizes the processes that lead to formation of these structures.', select the correct biomedical concept corresponding to 'pv'. Answer using one of the provided options. | <Options>: A: pestivirus p
B: porcine parvovirus (ppv (aka porcine parvovirus))
C: pestivirus o
D: perrin park virus
E: pestivirus
F: None of the above. | F |
<Instruct>: Given the context 'Poliovirus (PV) is a plus-strand RNA virus containing a genome that is a functional mRNA; thus, we investigated if PV antagonizes the processes that lead to formation of these structures.', select the correct biomedical concept corresponding to 'pv'. Answer using one of the provided options. | <Options>: A: pestivirus c (aka pestivirus suis)
B: plasmid ppv
C: penalva
D: perrin park virus
E: pestivirus o
F: None of the above. | F |
<Instruct>: Given the context 'Poliovirus (PV) is a plus-strand RNA virus containing a genome that is a functional mRNA; thus, we investigated if PV antagonizes the processes that lead to formation of these structures.', select the correct biomedical concept corresponding to 'pv'. Answer using one of the provided options. | <Options>: A: pv1 (aka poliovirus 1) (aka poliovirus 1)
B: pestivirus f (aka pestivirus australiaense)
C: transformation vector pv1
D: penalva
E: pestivirus
F: None of the above. | F |
<Instruct>: Given the context 'We have previously shown that PV infection inhibits the ability of cells to form stress granules by cleaving RasGAP-SH3-binding protein (G3BP).', select the correct biomedical concept corresponding to 'pv'. Answer using one of the provided options. | <Options>: A: porcine parvovirus (ppv (aka porcine parvovirus))
B: pv1 (aka poliovirus 1) (aka poliovirus 1)
C: p virus
D: pestivirus d (aka pestivirus ovis)
E: perrin park virus
F: None of the above. | F |
<Instruct>: Given the context 'Here, we show that P bodies are also disrupted during PV infection in cells by 4 h postinfection.', select the correct biomedical concept corresponding to 'pv'. Answer using one of the provided options. | <Options>: A: pestivirus
B: pestivirus a (aka pestivirus bovis)
C: transformation vector pv1
D: transfection vector pvv
E: porcine pestivirus
F: None of the above. | F |
<Instruct>: Given the context 'Two factors involved in 5'-end mRNA decapping and degradation, Xrn1 and Dcp1a, and the 3' deadenylase complex component Pan3 underwent accelerated degradation during infection, and Dcp1a may be a direct substrate of PV 3C proteinase.', select the correct biomedical concept corresponding to 'pv'. Answer using one of the provided options. | <Options>: A: pv1 (aka poliovirus 1) (aka poliovirus 1)
B: veprecula
C: pestivirus
D: pestivirus p
E: transfection vector pvv
F: None of the above. | F |
<Instruct>: Given the context 'Several other key factors proposed to be essential for P body formation, GW182, Edc3, and Edc4, were unaffected by poliovirus infection.', select the correct biomedical concept corresponding to 'poliovirus'. Answer using one of the provided options. | <Options>: A: unidentified poliovirus
B: human poliovirus 3 (aka poliovirus 3)
C: murine poliovirus (aka theiler's encephalomyelitis virus)
D: p virus
E: poliovirus (aka enterovirus c)
F: None of the above. | E |
<Instruct>: Given the context 'The magnitude of local immunity in the lungs of mice induced by live attenuated influenza vaccines is determined by local viral replication and induction of cytokines.
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: eastern european house mouse (aka mus musculus musculus)
C: mice (aka mus sp.) (aka mus sp.)
D: mus molossinus (aka mus musculus molossinus)
E: western wild mouse (aka mus spretus)
F: None of the above. | A |
<Instruct>: Given the context 'While live attenuated influenza vaccines (LAIVs) have been shown to be efficacious and have been licensed for human use, the surface glycoproteins hemagglutinin (HA) and neuraminidase (NA) have to be updated for optimal protective efficacy.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: sphaeria humana (aka sordaria humana)
B: great apes (aka hominidae)
C: pediculus humanus (human louse) (aka pediculus humanus)
D: human (aka homo sapiens)
E: gymnopleurus humanus
F: None of the above. | D |
<Instruct>: Given the context 'A panel of LAIVs that share the internal protein genes, with unique HA and NA gene segments from different influenza subtypes, was rescued by reverse genetics, and a comparative study of immune responses induced by these vaccines was conducted in mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: mus musculus (house mouse) (aka mus musculus)
D: mus famulus (servant mouse) (aka mus famulus)
E: western wild mouse (aka mus spretus)
F: None of the above. | C |
<Instruct>: Given the context 'A qualitative analysis of immune responses induced by a single dose of an H5N1 LAIV revealed that the vaccine induced robust systemic and mucosal immunity in mice.', select the correct biomedical concept corresponding to 'h5n1'. Answer using one of the provided options. | <Options>: A: equine influenza virus
B: influenza virus type a (aka influenza a virus)
C: alphainfluenzavirus influenzae
D: avian influenza virus (aka unidentified influenza virus)
E: avian influenza virus h5n1 (aka h5n1 subtype)
F: None of the above. | B |
<Instruct>: Given the context 'A qualitative analysis of immune responses induced by a single dose of an H5N1 LAIV revealed that the vaccine induced robust systemic and mucosal immunity in mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus musculus castaneus (southeastern asian house mouse) (aka mus musculus castaneus)
C: mice (aka mus sp.) (aka mus sp.)
D: mus molossinus (aka mus musculus molossinus)
E: mus famulus (servant mouse) (aka mus famulus)
F: None of the above. | A |
<Instruct>: Given the context 'A qualitative analysis of immune responses induced by a single dose of an H5N1 LAIV revealed that the vaccine induced robust systemic and mucosal immunity in mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: western wild mouse (aka mus spretus)
B: southeastern asian house mouse (aka mus musculus castaneus)
C: mus domesticus (aka mus musculus domesticus)
D: mus famulus (servant mouse) (aka mus famulus)
E: mus terricolor (earth-colored mouse) (aka mus terricolor)
F: None of the above. | F |
<Instruct>: Given the context 'In addition, antibodies and memory lymphocytes established in the lungs following vaccination were required for protection against lethal challenge with homologous and heterologous H5N1 viruses.', select the correct biomedical concept corresponding to 'h5n1 viruses'. Answer using one of the provided options. | <Options>: A: gammainfluenzavirus influenzae
B: influenza c viruses (aka influenza c virus)
C: influenza virus (aka unidentified influenza virus)
D: fluav (aka influenza a virus)
E: duck influenza virus
F: None of the above. | D |
<Instruct>: Given the context 'Transgenic expression of the RNA-dependent RNA polymerase 3D(pol) inhibited infection of Theiler's murine encephalitis virus (TMEV), a picornavirus from which it was derived.', select the correct biomedical concept corresponding to 'theiler's murine encephalitis virus'. Answer using one of the provided options. | <Options>: A: murray valley encephalitis virus
B: cardiovirus b1 (theiler's murine encephalomyocarditis virus) (aka cardiovirus b1)
C: theiler's murine encephalomyelitis virus tmev (aka theiler's encephalomyelitis virus)
D: tick-borne encephalitis virus tbev (aka tick-borne encephalitis virus)
E: mev (aka mink enteritis virus) (aka mink enteritis virus)
F: None of the above. | F |
<Instruct>: Given the context 'Transgenic expression of the RNA-dependent RNA polymerase 3D(pol) inhibited infection of Theiler's murine encephalitis virus (TMEV), a picornavirus from which it was derived.', select the correct biomedical concept corresponding to 'tmev'. Answer using one of the provided options. | <Options>: A: turkey meningoencephalitis virus
B: mott virus
C: tmuv (aka tembusu virus) (aka tembusu virus)
D: tt virus (aka torque teno virus)
E: telmo virus
F: None of the above. | F |
<Instruct>: Given the context 'Here, we infected 3D(pol) transgenic mice with another picornavirus, as well as an alphaherpesvirus and a rhabdovirus.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus famulus (servant mouse) (aka mus famulus)
B: mice (aka mus sp.) (aka mus sp.)
C: mus californicus (aka peromyscus californicus)
D: mus musculus castaneus (southeastern asian house mouse) (aka mus musculus castaneus)
E: mouse (aka mus musculus)
F: None of the above. | E |
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