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Surgical Management of Patients With COVID-19 Infection. Recommendations of the Spanish Association of Surgeons | Abstract Due to the current pandemic of respiratory disease known as coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 virus, many patients with confirmed or suspected COVID-19 infection will require elective surgery, surgery that cannot be postponed, or emergency surgical treatment. In these situations, spe... |
Impact of Coronavirus disease-19 (COVID-19) lockdown on physical activity and energy expenditure among physiotherapy professionals and students using web based open E-survey sent through WhatsApp, Facebook and Instagram messengers | BACKGROUND: Coronavirus disease - 19 (COVID-19) spread throughout the world and become pandemic. To stop and control the rapid infection of COVID-19 lockdown is the best option. Sudden lockdown implies change in entire lifestyle of the population. Social isolation affects individual's lives by greater reduction in thei... |
Management of critically ill patients with COVID-19 in ICU: statement from front-line intensive care experts in Wuhan, China | BACKGROUND: The ongoing coronavirus disease 2019 (COVID-2019) pandemic has swept all over the world, posing a great pressure on critical care resources due to large number of patients needing critical care. Statements from front-line experts in the field of intensive care are urgently needed. METHODS: Sixteen front-lin... |
Multidisciplinary management of the burn injured patient during a pandemic -– The role of telemedicine | |
Arapan-S: a fast and highly accurate whole-genome assembly software for viruses and small genomes | BACKGROUND: Genome assembly is considered to be a challenging problem in computational biology, and has been studied extensively by many researchers. It is extremely difficult to build a general assembler that is able to reconstruct the original sequence instead of many contigs. However, we believe that creating specif... |
Do Humidity and Temperature Impact the Spread of the Novel Coronavirus? | |
Rapid Identification of Potential Inhibitors of SARS‐CoV‐2 Main Protease by Deep Docking of 1.3 Billion Compounds | The recently emerged 2019 Novel Coronavirus (SARS‐CoV‐2) and associated COVID‐19 disease cause serious or even fatal respiratory tract infection and yet no approved therapeutics or effective treatment is currently available to effectively combat the outbreak. This urgent situation is pressing the world to respond with ... |
Response and Operating Room Preparation for the COVID-19 Outbreak: A Perspective from the National Heart Centre Singapore | Abstract The outbreak of COVID-19, a respiratory disease from a novel coronavirus that was first detected in Wuhan City, Hubei Province, China is now a public health emergency and fast approaching a pandemic. Singapore, as a major international transportation hub in Asia, is one of the worst hit countries of COVID-19. ... |
COVID-19 in an Adult with Tricuspid Atresia S/P Fontan Palliation | Abstract: December 2019, a pathogenic novel human coronavirus (HCoV), termed SARS-CoV-2, was recognized in Wuhan, China causing significant morbidity and mortality. The illness caused by SARS-CoV-2 is labelled COVID-19 by WHO. We report the first case of COVID-19 in an ACHD patient with Single Ventricle (SV) physiology... |
Recognition and analysis of protein-coding genes in severe acute respiratory syndrome associated coronavirus | Motivation: The recent outbreak of severe acute respiratory syndrome (SARS) caused by SARS coronavirus (SARS-CoV) has necessitated an in-depth molecular understanding of the virus to identify new drug targets. The availability of complete genome sequence of several strains of SARS virus provides the possibility of iden... |
How Volunteers Are Dealing With Coronavirus Issues | |
Clinical characteristics and risk factors of mild‐to‐moderate COVID‐19 patients with false‐negative SARS‐CoV‐2 nucleic acid | This study investigates the clinical and imaging characteristics of coronavirus disease 2019 (COVID‐19) patients with false‐negative nucleic acids. Mild‐to‐moderate COVID‐19 patients, including 19 cases of nucleic acid false‐negative patients and 31 cases of nucleic acid positive patients, were enrolled. Their epidemio... |
Adenovirus behavior in air handling unit fiberglass filters | Viral aerosols can lead to respiratory viral infections with high infectivity. About 90% of people’s time is spent in closed environments. A few studies have pointed out that the ventilation systems in air handling units (AHUs) that treat and transmit a new synthetic clean and conditioned environment can also spread an... |
Detection of the Severe Acute Respiratory Syndrome‐Related Coronavirus and Alphacoronavirus in the Bat Population of Taiwan | Bats have been demonstrated to be natural reservoirs of severe acute respiratory syndrome coronavirus (SARS CoV) and Middle East respiratory syndrome (MERS) CoV. Faecal samples from 248 individuals of 20 bat species were tested for partial RNA‐dependent RNA polymerase gene of CoV and 57 faecal samples from eight bat sp... |
Taiwan quality indicator project and hospital productivity growth | Abstract The Taiwan Quality Indicator Project (TQIP) is a quality management program that measures and monitors the healthcare quality of hospitals in Taiwan. This paper examines the impact of TQIP participation on hospital productivity growth with the application of the Malmquist productivity change index based on dat... |
Characteristics of human metapneumovirus infection in adults hospitalized for community-acquired influenza-like illness in France, 2012-2018: a retrospective observational study | Abstract Objectives To describe the prevalence, clinical features and complications of human metapneumovirus (hMPV) infections in a population of adults hospitalized with influenza-like illness (ILI). Methods This was a retrospective, observational, multicenter cohort study using prospectively collected data from adult... |
A short sequence in the COOH-terminus makes an adenovirus membrane glycoprotein a resident of the endoplasmic reticulum | Abstract The E19 protein of adenoviruses is a transmembrane protein that abrogates the intracellular transport of class I antigens by forming complexes with them in the ER. We show here that the E19 protein is retained in the ER even in the absence of class I antigens. To define the region conferring residency in the E... |
Influence of the coronavirus 2 (SARS-Cov-2) pandemic on acute appendicitis() | INTRODUCTION: Acute appendicitis (AA) is the most common abdominal surgical emergency. No specific studies have been found that evaluate the impact of the coronavirus 2 (SARS-Cov-2) pandemic on AA and its surgical management. An analysis was made on the influence of this new pathology on the clinical course of AA. MATE... |
Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA sequencing | BACKGROUND: Amino acid substitutions in the target enzyme Erg11p of azole antifungals contribute to clinically-relevant azole resistance in Candida albicans. A simple molecular method for rapid detection of ERG11 gene mutations would be an advantage as a screening tool to identify potentially-resistant strains and to t... |
Take Advantage of Lessons Learned During the Pandemic | The COVID‐19 pandemic has had wide‐ranging effects on the water industry, but now you and your colleagues are getting your utility back to “normal,” whatever normal now means. As of this writing in mid‐May, events are still moving unexpectedly and unevenly, so some things still can't be predicted. However, the fundamen... |
Reflection on passive immunotherapy in those who need most: some novel strategic arguments for obtaining safer therapeutic plasma or autologous antibodies from recovered COVID ‐19 infected patients | COVID‐19 pandemic is an emerging new human disease, where no vaccines, or monoclonal antibodies (mAbs), or drugs are currently available for therapy. Active vaccination requires the induction of an immune response against a given agent to a susceptible individual for the purpose of preventing or treating an infectious ... |
Low performance of rapid antigen detection test as frontline testing for COVID-19 diagnosis | BACKGROUND: Ensuring accurate diagnosis is essential to limit the spread of the SARS-CoV-2 and for the clinical management of COVID-19. Although real-time reverse transcription polymerase chain reaction (RT- qPCR) is the current recommended laboratory method to diagnose SARS-CoV-2 acute infection, several factors such ... |
Comparison of a new Eulerian model with a modified Lagrangian approach for particle distribution and deposition indoors | Abstract Understanding of aerosol dispersion characteristics has many scientific and engineering applications. It is recognized that Eulerian or Lagrangian approach has its own merits and limitations. A new Eulerian model has been developed and it adopts a simplified drift–flux methodology in which external forces can ... |
Hospital‐based dental externship during COVID‐19 pandemic: Think virtual! | |
MRI findings of neuronal ceroid lipofuscinosis in a cat | CASE SUMMARY: A 2-year-old male domestic shorthair cat presented to the University of Liverpool Small Animal Teaching Hospital with a 2 week history of altered mentation, blindness and focal epileptic seizures. MRI examination revealed generalised cerebral and cerebellar atrophy, diffuse T2-weighted hyperintensity of t... |
Virus Pathogen Database and Analysis Resource (ViPR): A Comprehensive Bioinformatics Database and Analysis Resource for the Coronavirus Research Community | Several viruses within the Coronaviridae family have been categorized as either emerging or re-emerging human pathogens, with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) being the most well known. The NIAID-sponsored Virus Pathogen Database and Analysis Resource (ViPR, www.viprbrc.org) supports bioinformat... |
The rumouring of SARS during the 2003 epidemic in China | By analysing rumour content as covered by major Chinese newspapers, this article explores the multiple dimensions of SARS‐related rumouring throughout China during the 2003 epidemic. Findings indicate a strong correlation between the scale of SARS infections and level of rumour activities across regions. As for channel... |
Selection of reference genes for quantitative real-time PCR in bovine preimplantation embryos | BACKGROUND: Real-time quantitative PCR is a sensitive and very efficient technique to examine gene transcription patterns in preimplantation embryos, in order to gain information about embryo development and to optimize assisted reproductive technologies. Critical to the succesful application of real-time PCR is carefu... |
Effect of Chicken Egg Yolk Antibodies (IgY) against Diarrhea in Domesticated Animals: A Systematic Review and Meta-Analysis | BACKGROUND: IgY antibodies are serum immunoglobulin in birds, reptiles and amphibians, and are transferred from serum to egg yolk to confer passive immunity to their embryos and offspring. Currently, the oral passive immunization using chicken IgY has been focused as an alternative to antibiotics for the treatment and ... |
Covid19 y cronicidad. Una oportunidad de reinventar los servicios de medicina física y rehabilitación | |
Middle East Respiratory Syndrome Coronavirus Infection in Dromedary Camels in Saudi Arabia | The Middle East respiratory syndrome (MERS) is proposed to be a zoonotic disease; however, the reservoir and mechanism for transmission of the causative agent, the MERS coronavirus, are unknown. Dromedary camels have been implicated through reports that some victims have been exposed to camels, camels in areas where th... |
Recombinase polymerase amplification–nucleic acid lateral flow immunoassays for Newcastle disease virus and infectious bronchitis virus detection | Newcastle disease virus (NDV) and infectious bronchitis virus (IBV) are two poultry pathogens affecting the respiratory tract of chickens, and cause major economic losses in the industry. Rapid detection of these viruses is crucial to inform implementation of appropriate control measures. The objective of our study is ... |
COVID‐19: How Can Rural Community Pharmacies Respond to the Outbreak? | |
Expected immunizations and health protection for Hajj and Umrah 2018 —An overview | Abstract Background The annual Hajj and Umrah are one of the largest recurring religious mass gatherings across the globe drawing pilgrims from more than 185 countries. The living circumstances and activities of the pilgrims may create an environment for the occurrence and spread of communicable diseases. Each year, th... |
Un numéro spécial Covid-19 du Journal de chirurgie viscérale : quels problèmes, quels dangers et quelles solutions sont identifiés? | |
Guide pratique pour la radiothérapie des hémopathies malignes dans la situation d’épidémie de covid-19 : recommandations de l’International Lymphoma Radiation Oncology Group | |
Mechanisms of epithelial damage: are there parallels between bullous skin diseases and asthma? | |
Crystal structures of Nipah and Hendra virus fusion core proteins | The Nipah and Hendra viruses are highly pathogenic paramyxoviruses that recently emerged from flying foxes to cause serious disease outbreaks in humans and livestock in Australia, Malaysia, Singapore and Bangladesh. Their unique genetic constitution, high virulence and wide host range set them apart from other paramyxo... |
Development of a porcine epidemic diarrhea virus M protein-based ELISA for virus detection | A membrane (M), protein-based ELISA was developed to detect porcine epidemic diarrhea virus (PEDV). The M gene of PEDV was expressed in Escherichia coli. The purified recombinant M protein was used to immunize rabbits to generate a polyclonal antibody. Immunofluorescence analysis indicated that the anti-PEDV-M antibody... |
DETECCIÓN VIRAL Y RESPUESTA SEROLÓGICA EN PACIENTES CRÍTICOS INTUBADOS CON SARS-CoV-2. IMPLICACIONES PARA RETIRADA DE AISLAMIENTO | |
Reply to “Indications and timing for tracheostomy in patients with SARS CoV2‐related” by Ferri et al. | |
The Nrf2 Activator (DMF) and Covid-19: Is there a Possible Role? | INTRODUCTION: COVID-19 is a new viral illness that can affect the lungs and airways with lethal consequences leading to the death of the patients. The ACE2 receptors were widely disturbed among body tissues such as lung, kidney, small intestine, heart, and others in different percent and considered a target for the nCO... |
Anti-Infectious Plants of the Thai Karen: A Meta-Analysis | Pharmacology has developed many drugs to treat infections, but many people, especially in developing countries, cannot afford to purchase them, and still depend on traditional knowledge and local medicinal plants to fight off infections. In addition, numerous microbes have developed resistance to the pharmaceutical dru... |
Clinical exacerbation of SARS‐CoV2 infection after fingolimod withdrawal | The role of disease‐modifying therapies in patients with autoimmune disorders during SARS‐CoV2 infection is controversial. Immunocompromised patients could have a more severe COVID‐19 disease, due to the absence of an adequate immune response against the SARS‐CoV‐2. However, therapies that act on immune response could ... |
Endoplasmic Reticulum Stress Interacts With Inflammation in Human Diseases | The endoplasmic reticulum is a critical organelle for normal cell function and homeostasis. Disturbed protein folding process in the ER, termed ER stress, leads to the activation of unfolded protein response (UPR) that encompasses a complex network of intracellular signaling pathways. The UPR can either restore ER home... |
Evaluating Detection of an Inhalational Anthrax Outbreak | Timely detection of an inhalational anthrax outbreak is critical for clinical and public health management. Syndromic surveillance has received considerable investment, but little is known about how it will perform relative to routine clinical case finding for detection of an inhalational anthrax outbreak. We conducted... |
Development and Initial Validation of the COVID Stress Scales | Abstract Research and clinical observations suggest that during times of pandemic many people exhibit stress- or anxiety-related psychopathology that include fear of becoming infected, fear of coming into contact with possibly contaminated objects or surfaces, fear of foreigners who might be carrying infection (i.e., d... |
Drug Repurposing for Japanese Encephalitis Virus Infection by Systems Biology Methods | Japanese encephalitis is a zoonotic disease caused by the Japanese encephalitis virus (JEV). It is mainly epidemic in Asia with an estimated 69,000 cases occurring per year. However, no approved agents are available for the treatment of JEV infection, and existing vaccines cannot control various types of JEV strains. D... |
Six pioneers artistically celebrated by the Andalusian Society of Nuclear Medicine | |
Thinking outside the (acrylic) box: a framework for the local use of custom‐made medical devices | Before the COVID‐19 pandemic, clinicians were already adept at creating workarounds for day‐to‐day shortages of equipment, inventively cobbling together substitute gadgets together to fulfil a clinical need. This is colloquially known as ‘jury‐rigging’ or ‘MacGyvering’, the latter taken from the eponymous 1980s televis... |
COVID-19 Follow up Testing | • Positive cases of SARS-CoV-2 were seen in the Mayo Clinic FL COVID Virtual Clinic. • 70% of patients met CDC guidelines for release from quarantine & still tested (+); • The average time from onset of symptoms to negative testing was 19 days. |
Provision of Speech-Language Pathology Services for the Treatment of Speech and Language Disorders in Children during the COVID-19 Pandemic: Problems, Concerns, and Solutions | Recently, a novel virus has spread worldwide causing the disease called COVID-19. In addition to putting people’s lives at risk and causing mortality, various problems have occurred due to the negative effects of the COVID-19 pandemic. Quarantine, social distancing, and the obligation to use protective tools have led t... |
Endoplasmic Reticulum Calcium Pumps and Tumor Cell Differentiation | Endoplasmic reticulum (ER) calcium homeostasis plays an essential role in cellular calcium signaling, intra-ER protein chaperoning and maturation, as well as in the interaction of the ER with other organelles. Calcium is accumulated in the ER by sarco/endoplasmic reticulum calcium ATPases (SERCA enzymes) that generate ... |
Medical Student Mobilization During a Crisis: Lessons From a COVID-19 Medical Student Response Team | On March 17, 2020, the Association of American Medical Colleges recommended the suspension of all direct patient contact responsibilities for medical students because of the COVID-19 pandemic. Given this change, medical students nationwide had to grapple with how and where they could fill the evolving needs of their sc... |
Coalition: Advocacy for prospective clinical trials to test the post-exposure potential of hydroxychloroquine against COVID-19 | Abstract Our coalition of public health experts, doctors, and scientists worldwide want to draw attention to the need for high-quality evaluation protocols of the potential beneficial effect of hydroxychloroquine (HCQ) as a post-exposure drug for exposed people, meaning people with close contact with positive tested pa... |
Breaking Bad: How Viruses Subvert the Cell Cycle | Interactions between the host and viruses during the course of their co-evolution have not only shaped cellular function and the immune system, but also the counter measures employed by viruses. Relatively small genomes and high replication rates allow viruses to accumulate mutations and continuously present the host w... |
Chilblain‐like lesions in pediatrics dermatological outpatients during the COVID‐19 outbreak | |
Back to the spring of Wuhan: facts and hope of COVID-19 outbreak | |
Factors Associated with Hospitalization and Disease Severity in a Racially and Ethnically Diverse Population of COVID-19 Patients | Background: The coronavirus disease (COVID-19) first identified in Wuhan in December 2019 became a pandemic within a few months of its discovery. The impact of COVID-19 is due to both its rapid spread and its severity, but the determinants of severity have not been fully delineated. Objective: Identify factors associat... |
Human Coronavirus Infections in Rural Thailand: A Comprehensive Study Using Real-Time Reverse-Transcription Polymerase Chain Reaction Assays | Background. We sought to determine whether infections with human coronaviruses (HCoVs) 229E, OC43, HKU1, and NL63 are associated with pneumonia and to define the epidemiology of HCoV infection in rural Thailand. Methods. We developed a real-time reverse-transcription polymerase chain reaction (RT-PCR) assay panel for t... |
A comparative epidemiologic analysis of SARS in Hong Kong, Beijing and Taiwan | BACKGROUND: The 2002-2003 Severe Acute Respiratory Syndrome (SARS) outbreak infected 8,422 individuals leading to 916 deaths around the world. However, there have been few epidemiological studies of SARS comparing epidemiologic features across regions. The aim of this study is to identify similarities and differences i... |
Carbochips: a new energy for old biobuilders | Abstract Microarray technology has come of age for use in high-throughput operations and large-scale studies. It allows rapid and simultaneous detection of thousands of parameters within a single experiment. Recent developments in the field of carbohydrate microarray technology facilitate applications for different typ... |
Does genetic diversity limit disease spread in natural host populations? | It is a commonly held view that genetically homogenous host populations are more vulnerable to infection than genetically diverse populations. The underlying idea, known as the ‘monoculture effect,' is well documented in agricultural studies. Low genetic diversity in the wild can result from bottlenecks (that is, found... |
Capacity and the COVID Surge | |
Systematic review with meta-analysis of the accuracy of diagnostic tests for COVID-19 | OBJECTIVE: . To collate the evidence on the accuracy parameters of all available diagnostic methods for detecting SARS-CoV-2. METHODS: . A systematic review with meta-analysis was performed. Searches were conducted in Pubmed and Scopus (April 2020). Studies reporting data on sensitivity or specificity of diagnostic tes... |
Early childhood environmental education: A systematic review of the research literature | Abstract Environmental education focused on the early-childhood years is experiencing dynamic growth in research and practice due to persistent environmental challenges coupled with burgeoning interest in the documented benefits of nature-rich experiences for infants and children. To better understand the landscape of ... |
Making prevention pay | Funding for biodefense is spurring new vaccine and anti-infective programs at several biotech companies. |
Characterization and membrane gene-based phylogenetic analysis of avian infectious bronchitis virus Chinese strain HH06 | A Chinese isolate of avian infectious bronchitis virus (IBV) designated HH06 was isolated from the kidney tissues of a chicken flock experiencing an outbreak of nephritis. In vivo pathogenicity of the IBV isolate HH06 was determined by inoculating specific pathogen-free (SPF) chickens. The clinical signs and related gr... |
High‐cell‐passage canine coronavirus vaccine providing sterilising immunity | Objectives: To evaluate the ability of a high‐cell‐passage canine coronavirus vaccine to immunise dogs against challenge with a field isolate of the virus. Methods: Three dogs that had previously tested seronegative and virus‐negative for canine coronavirus were inoculated twice, at 21‐day intervals, with the vaccine a... |
Management of Pemphigus in COVID-19 Pandemic Era; a Review Article | The novel coronavirus is rapidly spreading around the world. Since the public announcement of the COVID-19 outbreak, several concerns have been raised by dermatologists as well as pemphigus patients who take immunosuppressive drugs. In this paper, we review the literature about the common treatment of pemphigus with a ... |
CD133作为肺癌干细胞标记物的应用及其局限性 | Lung cancer is one of the most common tumor, which lacks of effective clinical treatment to lead to desirable prognosis. According to cancer stem cell hypothesis, lung cancer stem cells are considered to be responsible for carcinogenesis, development, metastasis, recurrence, invasion, resistance to chemotherapy and rad... |
Reply to correspondence: Vaginal Delivery in a Woman Infected With SARS-CoV-2 - The First Case Reported in Portugal | |
Managing Cancer Care during the COVID-19 Pandemic and Beyond | Abstract COVID-19 pandemic has posed insurmountable challenges to health care systems globally. Cancer therapy is complex, and outcomes are centered on timing. Many oncology societies and health ministries have issued guidelines for cancer care to enable oncologists and patients navigate the crisis. Lessons learned sho... |
Multihospital Outbreak of a Middle East Respiratory Syndrome Coronavirus Deletion Variant, Jordan: A Molecular, Serologic, and Epidemiologic Investigation | BACKGROUND: An outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) in Jordan in 2015 involved a variant virus that acquired distinctive deletions in the accessory open reading frames. We conducted a molecular and seroepidemiologic investigation to describe the deletion variant’s transmission patterns an... |
Porcine adenovirus as a delivery system for swine vaccines and immunotherapeutics | Abstract Porcine adenovirus (PAdV) has many qualities which make it an ideal choice for use as a delivery vector in swine. It is a low grade pathogen, present almost world-wide in a number of serotypes varying in their virulence and tissue tropism, which may allow for serotype specific vaccine targeting. PAdV is specie... |
II n’y a pas de parallélisme entre les susceptibilités bactériologiques in vitro et la réponse clinique après une cure antibiotique intraveineuse dans la mucoviscidose A.L. Smith | Unknown |
Antibodies to coronaviruses are higher in older compared with younger adults and binding antibodies are more sensitive than neutralizing antibodies in identifying coronavirus‐associated illnesses | Human coronaviruses (HCoV) are common causes of respiratory illnesses (RI) despite preexisting humoral immunity. Sera were obtained near the onset of RI and 3 to 4 weeks later as part of a prospective study of 200 subjects evaluated for RI from 2009 to 2013. Antibodies against common HCoV strains were measured by enzym... |
Molecular methods for pathogen and microbial community detection and characterization: Current and potential application in diagnostic microbiology | Abstract Clinical microbiology laboratories worldwide have historically relied on phenotypic methods (i.e., culture and biochemical tests) for detection, identification and characterization of virulence traits (e.g., antibiotic resistance genes, toxins) of human pathogens. However, limitations to implementation of mole... |
Risk factors for a poor outcome among children admitted with clinically severe pneumonia to a university hospital in Rabat, Morocco | Summary Objectives Data on prognostic factors among children with severe pneumonia are scarce in middle-income countries. We investigated prognostic factors for an adverse outcome among children admitted to the Hôpital d’Enfants de Rabat, Morocco with World Health Organization-defined clinically severe pneumonia (CSP).... |
Identification of coronavirus sequences in carp cDNA from Wuhan, China | Severe acute respiratory syndrome (SARS)‐like coronavirus sequences were identified in two separate complementary DNA (cDNA) pools. The first pool was from a Carassius auratus (crusian carp) cell line and the second was from Ctenopharyngodon idella (grass carp) head kidney tissue. BLAST analysis suggests that these seq... |
The Neurobiology of Social Distance | Abstract Never before have we experienced social isolation on such a massive scale as we have in response to COVID-19. Yet we know that the social environment has a dramatic impact on our sense of life satisfaction and well-being. In times of distress, crisis, or disaster, human resilience depends on the richness and s... |
Post-SARS infection control in the hospital and clinic | Summary The recent severe acute respiratory syndrome (SARS) outbreak has almost mandated a re-evaluation of infection control practices in hospitals, clinics, schools and domestic environments, especially for patients with respiratory tract symptoms. Triage, early case detection followed by prompt isolation and quarant... |
A Feminist Perspective on COVID‐19 and the Value of Care Work Globally | The shared response to the COVID‐19 crisis demonstrates that the vast majority of society believes human well‐being ‐ not economic growth ‐ should be at the center of policy. COVID‐19 exposes the foundational role of care work, both paid and unpaid, to functioning societies and economies. Focusing on "production" inste... |
Low-level Circulation of Enterovirus D68–Associated Acute Respiratory Infections, Germany, 2014 | We used physician sentinel surveillance to identify 25 (7.7%) mild to severe infections with enterovirus D68 (EV-D68) in children and adults among 325 outpatients with acute respiratory infections in Germany during August–October 2014. Results suggested low-level circulation of enterovirus D68 in Germany. Viruses were ... |
Rewriting the rules for care of MDS and AML patients in the time of COVID-19 | Abstract The care of patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) has been radically altered by COVID-19, especially in New York City, the epicenter of the pandemic. Here we summarize how telemedicine, virtual visits, delayed transfusions, and chemotherapy, preferably selecting self-ad... |
Testing for SARS-CoV-2 (COVID-19): a systematic review and clinical guide to molecular and serological in-vitro diagnostic assays | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated Coronavirus disease 2019 (COVID-19) pandemic has demanded rapid upscaling of in-vitro diagnostic assays to enable mass screening and testing of high-risk groups, and simultaneous ascertainment of robust data on past SARS-CoV-2 exposure ... |
Documento de consenso sobre el diagnóstico y tratamiento de la faringoamigdalitis aguda | Resumen La faringoamigdalitis aguda (FAA) es una de las enfermedades más comunes en la infancia. La etiología más frecuente es vírica. Entre las causas bacterianas, el principal agente responsable es Streptococcus pyogenes o estreptococo beta hemolítico del grupo A (EbhGA). Las escalas de valoración clínica son una bue... |
The Stirling Protocol – Putting the environment at the heart of prosperity and social inclusion | Abstract While the global coronavirus crisis impacts society and the economy in a myriad of ways, it provides, what is likely to be, a once in a lifetime opportunity for us to rethink our response to climate change. According to the 2020 Global Risk Register, extreme weather and climate action failure are the two most ... |
A multipurpose portable negative air flow isolation chamber for aerosol generating medical procedures during the COVID-19 pandemic | |
Phosphorylation events during viral infections provide potential therapeutic targets | For many medically relevant viruses, there is now considerable evidence that both viral and cellular kinases play important roles in viral infection. Ultimately, these kinases, and the cellular signaling pathways that they exploit, may serve as therapeutic targets for treating patients. Currently, small molecule inhibi... |
Impact of the Autophagy Machinery on Hepatitis C Virus Infection | Autophagy is a cellular process that catabolizes cytoplasmic components and maintains energy homeostasis. As a stress response, the autophagy machinery interconnects a wide range of cellular pathways, enhancing the spread of certain pathogens while limiting others, and has become a highly active research area over the ... |
COVID-19 and One-Lung Ventilation | |
Lack of transmission among healthcare workers in contact with a case of Middle East respiratory syndrome coronavirus infection in Thailand | INTRODUCTION: A hospital-associated outbreak of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was reported. We aimed to assess the effectiveness of infection control measures among healthcare workers (HCWs) who were exposed to a MERS patient and/or his body fluids in our institute. METHODS: A descriptive stud... |
Priorisierung von Pflegeheimbewohnern aus notfallmedizinischer Sicht: Corona-Pandemie 2020 | Aus notfallmedizinischer Sicht sollten geriatrische Patienten in Pflege- und Seniorenheimen bereits vor einem „Massenanfall von infizierten Personen” eine Priorisierung auf der Basis des ACP(Advance Care Planning)-Konzepts erfahren. |
Epidemiology and Phylogenetic Analysis of Viral Respiratory Infections in Vietnam | Acute respiratory infections (ARIs) impose a major public health burden on fragile healthcare systems of developing Southeast Asian countries such as Vietnam. The epidemiology, genetic diversity and transmission patterns of respiratory viral pathogens that circulate in this region are not well characterized. We used RT... |
Anthropology: Anklebone kicks up primate debate | |
A case of mucolipidosis II presenting with prenatal skeletal dysplasia and severe secondary hyperparathyroidism at birth | Mucolipidosis II (ML II) or inclusion cell disease (I-cell disease) is a rarely occurring autosomal recessive lysosomal enzyme-targeting disease. This disease is usually found to occur in individuals aged between 6 and 12 months, with a clinical phenotype resembling that of Hurler syndrome and radiological findings res... |
Clinicopathological Phenotype of Autosomal Recessive Cholesterol Deficiency in Holstein Cattle | BACKGROUND: Cholesterol deficiency (CD), a newly identified autosomal recessive genetic defect in Holstein cattle, is associated with clinical signs of diarrhea, failure to thrive, and hypocholesterolemia. HYPOTHESIS/OBJECTIVES: The objective is to describe the clinicopathological phenotype of affected Holstein cattle ... |
Rotavirus I in feces of a cat with diarrhea | A divergent rotavirus I was detected using viral metagenomics in the feces of a cat with diarrhea. The eleven segments of rotavirus I strain Felis catus encoded non-structural and structural proteins with amino acid identities ranging from 25 to 79% to the only two currently sequenced members of that viral species both... |
New Metrics for Evaluating Viral Respiratory Pathogenesis | Viral pathogenesis studies in mice have relied on markers of severe systemic disease, rather than clinically relevant measures, to evaluate respiratory virus infection; thus confounding connections to human disease. Here, whole-body plethysmography was used to directly measure changes in pulmonary function during two r... |
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