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Diagnostic accuracy of two point‐of‐care kits for the diagnosis of Giardia species infection in dogs | OBJECTIVES: The objective of this study was to compare results obtained by ZnSO(4) Flotation and SNAP (®)Giardia to those generated by the new point‐of‐care tests Single and Triple Rapid. METHODS: Prospective study evaluating 51 canine faecal samples submitted at a reference laboratory for the presence of Giardia spp. ... |
Hospital Preparation for Severe Acute Respiratory Syndrome Using a Multidisciplinary Task Force | Abstract BACKGROUND: In March 2003, the severe acute respiratory syndrome (SARS) epidemic was recognized in China. The disease quickly spread to countries around the world and was transmitted in healthcare settings. Infection control professionals had to formulate a response to potential cases of SARS presenting to hea... |
Scientific Opinion on porcine epidemic diarrhoea and emerging porcine deltacoronavirus | In the last decade, many porcine epidemic diarrhoea (PED) outbreaks have been reported by several countries in Asia whereas only a few Member States of the European Union (EU) have reported PED clinical cases and/or PED virus (PEDV)‐seropositive animals. This alphacoronavirus was first reported in the USA in May 2013, ... |
Suppression of Coronavirus Replication by Cyclophilin Inhibitors | Coronaviruses infect a variety of mammalian and avian species and cause serious diseases in humans, cats, mice, and birds in the form of severe acute respiratory syndrome (SARS), feline infectious peritonitis (FIP), mouse hepatitis, and avian infectious bronchitis, respectively. No effective vaccine or treatment has be... |
Sex Differences in Mortality from COVID-19 Pandemic: Are Men Vulnerable and Women Protected? | Abstract Sex disaggregated data is an important for reducing health inequities in medicine. Global data suggests that is a sex difference in mortality from COVID-19. In this report, we explore plausible reasons for this sex difference including the contribution of underlying cardiovascular risk factors, high risk behav... |
Bench-to-bedside review: Rare and common viral infections in the intensive care unit – linking pathophysiology to clinical presentation | Viral infections are common causes of respiratory tract disease in the outpatient setting but much less common in the intensive care unit. However, a finite number of viral agents cause respiratory tract disease in the intensive care unit. Some viruses, such as influenza, respiratory syncytial virus (RSV), cytomegalovi... |
Broad-spectrum coronavirus antiviral drug discovery | Introduction: The highly pathogenic coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) are lethal zoonotic viruses that have emerged into human populations these past 15 years. These coronaviruses are associated with novel respiratory syndr... |
A Cured COVID-19 case of 86-year-old with 13 chronic diseases: A Case Report | |
Role of Glutathionylation in Infection and Inflammation | Glutathionylation, that is, the formation of mixed disulfides between protein cysteines and glutathione (GSH) cysteines, is a reversible post-translational modification catalyzed by different cellular oxidoreductases, by which the redox state of the cell modulates protein function. So far, most studies on the identific... |
Environmental Health and Bioterrorism☆ | Abstract Environment has complex and permanent relations with the biological warfare in comparison to other war types (conventional, nuclear, chemical). Changes of the environment interfere with many of the major determinants of biological warfare. The most probable type and the key issue of biological war is bioterror... |
Colonization and infection of the respiratory tract: What do we know? | |
Development and optimization of plaque assays for rat coronaviruses | Abstract Plaque assays under Sephadex or agarose overlays are described for rat coronaviruses (RCVs) grown in L2 mouse fibroblasts. A plaque assay using Sephadex was simple; however, viable plaques could not be collected for propagation, and fixation was necessary before evaluation. Plaque formation under agarose was o... |
SARS-CoV nucleocapsid protein interacts with cellular pyruvate kinase protein and inhibits its activity | The pathogenesis of SARS-CoV remains largely unknown. To study the function of the SARS-CoV nucleocapsid protein, we have conducted a yeast two-hybrid screening experiment to identify cellular proteins that may interact with the SARS-CoV nucleocapsid protein. Pyruvate kinase (liver) was found to interact with SARS-CoV ... |
Análisis de las coinfecciones detectadas entre los virus gripales A y B y otros virus respiratorios, 2012-2013 | |
Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates | The novel coronavirus SARS-CoV-2 is the cause of Coronavirus Disease-2019 (COVID-19). The main receptor of SARS-CoV-2, angiotensin I converting enzyme 2 (ACE2), is now undergoing extensive scrutiny to understand the routes of transmission and sensitivity in different species. Here, we utilized a unique dataset of 410 v... |
Enablers of, and barriers to, optimal glove and mask use for routine care in the emergency department: an ethnographic study of Australian clinicians | Abstract Background The risk of healthcare-acquired infection increases during outbreaks of novel infectious diseases. Emergency department (ED) clinicians are at high risk of exposure to both these and common communicable diseases. Personal protective equipment (PPE) is recommended to protect clinicians from acquiring... |
Clinical analysis of pregnant women with 2019 novel coronavirus pneumonia | The aim is to evaluate pregnant women infected with coronavirus disease 2019 (COVID‐19) and provide help for clinical prevention and treatment. All five cases of pregnant women confirmed COVID‐19 were collected among patients who admitted to the Maternal and Child Hospital of Hubei Province between January 20 and Febru... |
Alternative Care Sites: An Option in Disasters | During the current COVID-19 pandemic, the limited surge capacity of the healthcare system is being quickly overwhelmed. Similar scenarios play out when an institution’s systems fail, or when local or regional disasters occur. In these situations, it becomes necessary to use one or more alternative care sites (ACS). Sit... |
Ancient recombination events and the origins of hepatitis E virus | BACKGROUND: Hepatitis E virus (HEV) is an enteric, single-stranded, positive sense RNA virus and a significant etiological agent of hepatitis, causing sporadic infections and outbreaks globally. Tracing the evolutionary ancestry of HEV has proved difficult since its identification in 1992, it has been reclassified seve... |
COVID-19: Role of neutrophil extracellular traps in acute lung injury | Abstract The COVID-19 pandemic has caused significant disease and loss of life worldwide. SARS-CoV-2 causes respiratory infection with pneumonia, acute respiratory distress syndrome (ARDS), coagulopathy, and multiorgan failure in a significant number of patients. The pathophysiology of this disease is still unknown. Ne... |
Tracking Nosocomial Diseases at Individual Level with a Real-Time Indoor Positioning System | Our research is motivated by the rapidly-evolving outbreaks of rare and fatal infectious diseases, for example, the severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome. In many of these outbreaks, main transmission routes were healthcare facility-associated and through person-to-person con... |
Reorienting entrepreneurial support infrastructure to tackle a social crisis: A rapid response | Abstract Chile is experiencing its worst economic and social crisis in decades, which is adversely impacting entrepreneurs and SMEs. Chile’s Economic Development Agency is seeking to support recovery efforts by reorienting its entrepreneurship programs and ecosystem support capacity. What makes the reorientation especi... |
Vitamin intervention for cytokine storm in the patients with coronavirus disease 2019 | |
Origin time and epidemic dynamics of the 2019 novel coronavirus | The 2019 novel coronavirus (2019-nCoV) have emerged from Wuhan, China. Studying the epidemic dynamics is crucial for further surveillance and control of the outbreak. We employed a Bayesian framework to infer the time-calibrated phylogeny and the epidemic dynamics represented by the effective reproductive number (Re) c... |
COVID-19 prevalence and fatality rates in association with air pollution emission concentrations and emission sources() | The novel coronavirus disease (COVID-19) is primarily respiratory in nature, and as such, there is interest in examining whether air pollution might contribute to disease susceptibility or outcome. We merged data on COVID-19 cumulative prevalence and fatality rates as of May 31, 2020 with 2014–2019 pollution data from ... |
The Fate of Mengovirus on Fiberglass Filter of Air Handling Units | One of the most important topics that occupy public health problems is the air quality. That is the reason why mechanical ventilation and air handling units (AHU) were imposed by the different governments in the collective or individual buildings. Many buildings create an artificial climate using heating, ventilation, ... |
Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial | OBJECTIVES: The hypothesis of the proposed intervention is that Granulocyte-macrophage colony-stimulating factor (GM-CSF) has profound effects on antiviral immunity, and can provide the stimulus to restore immune homeostasis in the lung with acute lung injury post COVID-19, and can promote lung repair mechanisms, that ... |
Protests in Hong Kong (2019–2020): a Perspective Based on Quality of Life and Well-Being | Triggered by the Fugitive Offenders and Mutual Legal Assistance in Criminal Matters Legislation (Amendment) Bill 2019 in Hong Kong (Extradition Bill), many protests have taken place in Hong Kong in 2019–2020. Using a perspective based on quality of life and well-being in different ecological systems, it is argued that ... |
Antiviral and antiretroviral use in pregnancy | The history of antiviral and antiretroviral therapy is recent compared with many other medical therapies, including traditional antibiotics in pregnancy. There are few long-term data on which to base decisions of management in pregnancy. Accessing up-to-date information is critical to optimizing the safety of care for ... |
Invisibility and the extractive-pandemic nexus | • Covid-19 is reshaping the world economy. • Visibility of mining issues and social impacts is limited by the remote nature of extraction. • The pandemic is providing a platform for unchecked corporate self-ascriptions of virtue. • Regulatory control through public scrutiny has been suspended. • In this environment, sc... |
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring | Despite widespread concern for cytokine storms leading to severe morbidity in COVID-19, rapid cytokine assays are not routinely available for monitoring critically ill patients. We report the clinical application of a machine learning-based digital protein microarray platform for rapid multiplex quantification of cytok... |
Mechanisms of Innate Immune Evasion In Re-Emerging RNA Viruses | Recent outbreaks of Ebola, West Nile, Chikungunya, Middle Eastern Respiratory and other emerging/re-emerging RNA viruses continue to highlight the need to further understand the virus-host interactions that govern disease severity and infection outcome. As part of the early host antiviral defense, the innate immune sys... |
How COVID-19’s Disruption of the U.S. Correctional System Provides an Opportunity for Decarceration | The COVID-19 pandemic has amplified decades of vulnerabilities, disparities, and injustices within the U.S. correctional system. The spread of the coronavirus poses a particularly serious threat to those that comprise the system, including personnel, attorneys, prisoners, their families and extends into the communities... |
Multifunctional roles of leader protein of foot-and-mouth disease viruses in suppressing host antiviral responses | Foot-and-mouth disease virus (FMDV) leader protein (L(pro)) is a papain-like proteinase, which plays an important role in FMDV pathogenesis. L(pro) exists as two forms, Lab and Lb, due to translation being initiated from two different start codons separated by 84 nucleotides. L(pro) self-cleaves from the nascent viral ... |
Pig trade networks through live pig markets in Guangdong Province, China | This study used social network analysis to investigate the indirect contact network between counties through the movement of live pigs through four wholesale live pig markets in Guangdong Province, China. All 14,118 trade records for January and June 2016 were collected from the markets and the patterns of pig trade in... |
Chapter 9 Viral Strategies to Subvert the Mammalian Translation Machinery | Abstract Viruses do not carry their own protein biosynthesis machinery and the translation of viral proteins therefore requires that the virus usurps the machinery of the host cell. To allow optimal translation of viral proteins at the expense of cellular proteins, virus families have evolved a variety of methods to re... |
Active fractions of mannoproteins derived from yeast cell wall stimulate innate and acquired immunity of adult and elderly dogs | Abstract Nutritional intervention in older dogs aims to increase lifespan and improve life quality as well as delay the development of diseases related to ageing. It is believed that active fractions of mannoproteins (AFMs) obtained through extraction and fractionation of yeast cell walls (Saccharomyces cerevisiae) may... |
La batalla contra la enfermedad del Coronavirus 2019 (COVID-19): Manejo de Emergencia y Control de Infecciones en un Departamento de Radiología | Objetivo Describir las estrategias, manejo de emergencias y los procedimientos de control de infecciones de nuestro departamento durante el brote de la enfermedad por coronavirus 2019 (COVID-19). Métodos Creamos un equipo de manejo de emergencias. El equipo estableció varias medidas: Reconfiguración del flujo de trabaj... |
Viral infections in patients with acute respiratory infection in Northwest of Iran | INTRODUCTION: Acute respiratory infection (ARI) is one of the main causes of morbidity and mortality all around the world. The aim of this study was to determine the frequency, mortality and association with clinical entities of influenza virus type A, influenza virus type B, respiratory syncytial virus (RSV), coronavi... |
Nasal Infection of Enterovirus D68 Leading to Lower Respiratory Tract Pathogenesis in Ferrets (Mustela putorius furo) | Data from EV-D68-infected patients demonstrate that pathological changes in the lower respiratory tract are principally characterized by severe respiratory illness in children and acute flaccid myelitis. However, lack of a suitable animal model for EV-D68 infection has limited the study on the pathogenesis of this crit... |
Multiple gastric involvement by myeloid antigen CD13‐positive non‐secretory plasma cell leukaemia | Gastrointestinal tract involvement is a rare complication of plasma cell neoplasia. We present a case of non‐secretory type primary plasma cell leukaemia (PCL) with multiple gastric involvement. Dual surface antigen analysis of bone marrow cells revealed that atypical plasma cells coexpressed CD38 and myeloid antigen C... |
The determinants of Chinese visitors to Australia: A dynamic demand analysis | Although China has progressively become an important inbound tourism market for Australia, its demand elasticities have been little studied to date. This study examines the determinants of Chinese visitors to Australia using a dynamic time-series estimator. Interesting findings include a high income elasticity as a sou... |
Clinical features, diagnostics, and outcomes of patients presenting with acute respiratory illness: a comparison of patients with and without COVID-19 | BACKGROUND: Emerging data on the clinical presentation, diagnostics, and outcomes of patients with COVID-19 have largely been presented as case series. Few studies have compared these clinical features and outcomes of COVID-19 to other acute respiratory illnesses. METHODS: We examined all patients presenting to an emer... |
Integrating Biomedical, Ecological, and Sustainability Sciences to Manage Emerging Infectious Diseases | Globalization accelerates the mobilization of microorganisms via international trade and transport. Growth in population, increasing connectivity, and rapid urbanization all exacerbate the consequent risk of pandemics of zoonotic diseases. Global problems require global solutions, particularly the co-ordination of inte... |
Comment on “Central Nervous System Involvement by Severe Acute Respiratory Syndrome Coronavirus ‐2 (SARS‐CoV‐2)” | A very interesting report, for the first time, provided direct evidence that the ongoing pandemic etiological agent, SARS‐CoV‐2, may be able to directly infect central nervous system (CNS) through an endothelial route. If proven true, this may explain frequent neurological symptoms associated with severe COVID‐19 disea... |
Diagnostic Evaluation of Pulmonary Abnormalities in Patients with Hematologic Malignancies and Hematopoietic Cell Transplantation | Pulmonary complications (PC) of hematologic malignancies and their treatments are common causes of morbidity and mortality. Early diagnosis is challenging due to host risk factors, clinical instability, and provider preference. Delayed diagnosis impairs targeted treatment and may contribute to poor outcomes. An integra... |
Ad astra per aspera (Through Hardships to the Stars): Lessons Learned from the First National Virtual APDS Meeting, 2020 | OBJECTIVE: After COVID-19 rendered in-person meetings for national societies impossible in the spring of 2020, the leadership of the Association of Program Directors in Surgery (APDS) innovated via a virtual format in order to hold its national meeting. DESIGN: APDS leadership pre-emptively considered factors that woul... |
Review of international efforts to strengthen the global outbreak response system since the 2014–16 West Africa Ebola Epidemic | The 2014–16 West Africa Ebola epidemic was a watershed moment for global health. The outbreak galvanized global action around strengthening infectious disease prevention, detection and response capabilities. We examined the nascent landscape of international programmes, initiatives and institutions established in the a... |
Oil and Gas in the Age of COVID‐19 —Where Do They Go From Here? | Within the global financial chaos caused by the impacts of COVID‐19, the oil and natural gas production industry has been hit unusually hard. At the onset of the pandemic, oil was already experiencing severe market distress, as global supply exceeded global demand. OPEC had tried to craft a cutback in production, which... |
ACE2 and prognosis of COVID‐19. Insights from Bartter's and Gitelman's syndromes patients | The relationship between Renin‐Angiotensin system (RAS) and COVID‐19 pandemic and, in particular, RAS as part of the CoV‐2 infection process via Angiotensin Converting Enzyme 2 (ACE2), the entry point of SARS‐CoV‐2, has resulted in conflicting suggestions regarding how RAS and its role(s) should inform treating COVID‐1... |
Bracing for impact: operational upshots from the National Centre for Infectious Diseases Screening Centre (Singapore) during the COVID‐19 outbreak | To combat the ongoing COVID‐19 pandemic, Singapore has adopted a rigorous screening approach that involves aggressive contact tracing, rapid isolation of confirmed or suspect cases, and immediate ring‐fencing of emerging local clusters and hotspots. Our screening centre team has been involved in running Singapore's des... |
Interleukin-35 as an Emerging Player in Tumor Microenvironment | IL-35 is the newest member of IL-12 family. A dimeric protein consisting of two separate subunits has manifested suppressive actions on immune system, which is counterproductive in the context of cancers. Various reports have confirmed its inhibitory role on immune system which is carried out via formation of IL-35-pro... |
Q & A | Victorian corpse displays sparked John Troyer's interest in how humans use technology around dead bodies. He explores our fascination with death and its impact on life |
Microbiologic Methods in the Diagnostics of Upper Respiratory Tract Pathogens | Upper respiratory tract infection (URI) is a nonspecific term used to describe acute infections involving the nose, paranasal sinuses, pharynx, and larynx above the vocal cords. The aim of this study was to provide a summary of the most common pathogens of URI and to compare advantages and disadvantages of traditional ... |
Severe Acute Respiratory Syndrome: Pertinent Clinical Characteristics and Therapy | Severe acute respiratory syndrome (SARS) is a newly emerged infection that is caused by a previously unrecognized virus–a novel coronavirus designated as SARS-associated coronavirus (SARS-CoV). From November 2002 to July 2003 the cumulative number of worldwide cases was >8000, with a mortality rate of close to 10%. The... |
Effects of forced air warming systems on the airflow and sanitation quality of operating rooms with non-laminar airflow systems | BACKGROUND: : Previous studies have demonstrated that forced air warming (FAW) can be used safely in operating rooms with laminar airflow (LAF) ventilation systems. However, the effects of FAW on the airflow at surgical sites under non-LAF (nLAF) ventilation systems remain unclear, as nLAF systems generate outlet-to-in... |
Recombinant nucleocapsid protein-based IgG enzyme-linked immunosorbent assay for the serological diagnosis of SARS | Abstract The recombinant nucleocapsid protein (rNP) of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) was expressed in a baculovirus system. The purified SARS-CoV rNP was used as an antigen for detection of SARS-CoV antibodies in IgG enzyme-linked immunosorbent assay (ELISA). The ELISA was evaluated in... |
Leukoerythroblastic reaction in a patient with COVID‐19 infection | |
Imported and locally transmitted mild SARS-CoV-2 pneumonia cases in Japan | Abstract Here, we describe two mild SARS-CoV-2 pneumonia cases. One was imported from Wuhan, and the other was locally transmitted in Japan without recent travel to China. In both cases, lower respiratory tract symptoms were observed first, and high fever progressed in about one week. The laboratory findings revealed n... |
Measures to Prevent Healtcare Workers from Contracting Severe Acute Respiratory Syndrome During High-Risk Surgical Procedures | |
Abnormal liver tests in patients hospitalized with Coronavirus disease 2019: should we worry? | While several studies from China have reported COVID‐19‐related liver injury, there are currently no data on liver dysfunction in hospitalized COVID‐19 patients in Europe. The aim of this study was to describe the prevalence and predictive value of abnormal liver function in patients hospitalized with COVID‐19. This wa... |
Risk of coronavirus infections among medical personnel | |
Porcine Epidemic Diarrhea Virus Induces Autophagy to Benefit Its Replication | The new porcine epidemic diarrhea (PED) has caused devastating economic losses to the swine industry worldwide. Despite extensive research on the relationship between autophagy and virus infection, the concrete role of autophagy in porcine epidemic diarrhea virus (PEDV) infection has not been reported. In this study, a... |
Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study | BACKGROUND: The risk of severe COVID-19 if an individual becomes infected is known to be higher in older individuals and those with underlying health conditions. Understanding the number of individuals at increased risk of severe COVID-19 and how this varies between countries should inform the design of possible strate... |
Zoonoses in the Emergence of Human Viral Diseases | Viral zoonoses have represented a significant public health problem throughout history, affecting all continents. Furthermore, many viral zoonoses have emerged or reemerged in recent years, highlighting the importance of such diseases. Emerging viral zoonoses encompass a vast number of different viruses and many differ... |
Viral etiology of respiratory infections in children in southwestern Saudi Arabia using multiplex reverse-transcriptase polymerase chain reaction | OBJECTIVES: To investigate 15 respiratory viruses in children with acute respiratory tract infections (ARTIs) using multiplex reverse-transcriptase polymerase chain reaction (RT-PCR), and to analyze the clinical and epidemiological features of these viruses. METHODS: In a cross-sectional study, 135 children, ≤5 years o... |
Eliminating Visual Acuity and Dilated Fundus Exams Improves Cost Efficiency of Performing OCT-Guided Intravitreal Injections | PURPOSE: The clinic efficiency and cost savings achieved by eliminating formal visual acuity (VA) and dilated fundus exams (DFEs) were assessed for established patients receiving OCT-guided intravitreal injections. DESIGN: Comparative cost analysis METHODS: Two different treatment models were evaluated. The first model... |
Risks of ACE Inhibitor and ARB Usage in COVID‐19: Evaluating the Evidence | Concerns have been raised regarding the safety of angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) in patients with coronavirus disease of 2019 (COVID‐19), based on the hypothesis that such medications may raise expression of ACE2, the receptor for severe acute respiratory syndr... |
Indications and Findings on Transthoracic Echocardiogram in COVID-19 | ABSTRACT Background Despite growing evidence of cardiovascular complications associated with novel 2019 coronavirus disease (COVID-19), there is little data regarding the performance of transthoracic echocardiography (TTE) and spectrum of echocardiographic findings in this disease. Methods We performed a retrospective ... |
Plagues, Public Health, and Politics | |
Prevalence and Seasonal Distribution of Respiratory Viruses During the 2014 - 2015 Season in Istanbul | BACKGROUND: Acute respiratory tract infection (ARTI) is one of the most common infections worldwide, causing significant morbidity and mortality. OBJECTIVES: This study was conducted to determine the prevalence and seasonal distribution of respiratory viruses in our region, in children and adults with a pre-diagnosis o... |
Shedding of Neospora caninum oocysts by dogs fed different tissues from naturally infected cattle | Abstract Neospora caninum is one of the most important causes of abortion in dairy cattle worldwide. The distribution of N. caninum in tissues of adult cattle is unknown and the parasite has not been demonstrated histologically in tissues of cows. In the present study the distribution of N. caninum in different tissues... |
Group C Betacoronavirus in Bat Guano Fertilizer, Thailand | |
Bluetongue virus – 23 stimulates inducible nitric oxide synthase expression and nitric oxide production in mononuclear cells of blood and/or regional lymphoid organs | Mononuclear leukocytes of peripheral blood mononuclear cells (PBMCs) and regional lymphoid organs (RLOs) play a critical role in primary BTV replication and subsequent viral dissemination to distant systemic organs. The lesions in animals develop primarily as a result of vascular insult, presumably induced by the activ... |
Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation | Knowledge of the host factors required for norovirus replication has been hindered by the challenges associated with culturing human noroviruses. We have combined proteomic analysis of the viral translation and replication complexes with a CRISPR screen, to identify host factors required for norovirus infection. The co... |
The role of electron microscopy in the rapid diagnosis of viral infections — review | Electron microscopy (EM) allows fast visualization of viruses in a wide range of clinical specimens. Viruses are grouped into families based on their morphology. Viruses from various families look distinctly and these morphological variances are the basis for identification of viruses by EM. The identification to the f... |
Aligning the “Manifesto for a European Research Network into Problematic Usage of the Internet” with the Diverse Needs of the Professional and Consumer Communities Affected by Problematic Usage of Pornography | The Manifesto for a European research network into Problematic Usage of the Internet was published in May 2018. It was written from the perspective of the COST Action Network, a programme of the European Cooperation in Science and Technology CA16207 and is expected to have significant influence on research funding prio... |
Two outbreaks of SARS-CoV-2 in department of surgery in a Wuhan hospital | Summary The outbreak of SARS-CoV-2 in China, attracted a large number of medical staff to help in the city's hospitals and this put them at a high risk of infection. We describe twenty medical staff who were diagnosed with COVID-19 within one week in the department of surgery in a Wuhan hospital. Epidemiological invest... |
Vector competence of anthropophilic mosquitoes for a new mesonivirus in Senegal | The mesoniviruses (MESOVs) belong to the newly described Mesoniviridae family (Order: Nidovirales). They have never been reported in Senegal until recently during a study in arbovirus emergence with the detection of a new species of MESOV named Dianke virus (DKV) from common mosquitoes from eastern Senegal. Actually, t... |
The care of patients with Duchenne, Becker, and other muscular dystrophies in the COVID‐19 pandemic | The coronavirus disease 2019 (COVID‐19) pandemic has resulted in the reorganization of health‐care settings affecting clinical care delivery to patients with Duchenne and Becker muscular dystrophy (DBMD) as well as other inherited muscular dystrophies. The magnitude of the impact of this public health emergency on the ... |
Coinfections in Hospitalized Children With Community-Acquired Pneumonia: What Does This Mean for the Clinician? | |
V Repiratory Tract | Publisher Summary This chapter discusses respiratory tract. This chapter illustrates that a complex array of defensive mechanisms protect the lungs against the adverse effects of airborne substances and pathogenic organisms. In contrast to the adverse pulmonary effects of cigarette smoke and industrial pollutants, ther... |
Covid‐19 and neurodegeneration. What can we learn from the past? | Coronaviridae (CoVs) are single stranded RNA viruses. βeta‐CoVs encompasses Bat coronavirus (BCoV), the human Severe Acute Respiratory Syndrome (SARS) virus and the Middle Eastern Respiratory Syndrome (MERS) virus. In December 2019, a new βeta‐CoVs was identified in Wuhan, China, SARS‐CoV‐2. The genome sequencing demon... |
Vitamin D(3) and gargling for the prevention of upper respiratory tract infections: a randomized controlled trial | BACKGROUND: We undertook a 2X2 factorial, randomized controlled trial (RCT) to assess whether vitamin D(3) supplementation (10,000 international units per week) versus placebo and gargling versus no gargling could prevent viral, clinical upper respiratory tract infection (URTI) in university students. METHODS: We rando... |
COVID-19 Worries and Behavior Changes in Older and Younger Men and Women | OBJECTIVES: The case fatality rate of coronavirus disease 2019 (COVID-19) is higher among older adults than younger adults and is also higher among men than women. However, worry, which is a key motivator of behavioral health changes, occurs less frequently for older than younger adults, and less frequently for men tha... |
Algal Lectins as Potential HIV Microbicide Candidates | The development and use of topical microbicides potentially offers an additional strategy to reduce the spread of the Human Immunodeficiency Virus (HIV). Carbohydrate-binding agents (CBAs) that show specificity for high mannose carbohydrates on the surface of the heavily glycosylated envelope of HIV are endowed with po... |
Effect of Pullet Vaccination on Development and Longevity of Immunity | Avian respiratory disease causes significant economic losses in commercial poultry. Because of the need to protect long-lived poultry against respiratory tract pathogens from an early age, vaccination programs for pullets typically involve serial administration of a variety of vaccines, including infectious bronchitis ... |
T-01: Taux élevé d’infections respiratoires virales chez les patients hospitalisés et le personnel soignant, hiver 2014 | Introduction – objectifs Déterminer la prévalence des infections respiratoires virales symptomatiques ou non parmi les patients et les soignants d’un service de maladies infectieuses. Rechercher les facteurs associés à la transmission nosocomiale. Matériels et méthodes Les patients hospitalisés entre le 15/01 (S1) et l... |
Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review | At this time of the COVID-19 pandemic, potentially effective treatments are currently under urgent investigation. Benefits of chloroquine and hydroxychloroquine for the treatment of COVID-19 infection have been proposed and clinical trials are underway. Chloroquine and hydroxychloroquine, typically used for the treatme... |
The Emergence of Ebola as a Global Health Security Threat: From ‘Lessons Learned’ to Coordinated Multilateral Containment Efforts | First reported in remote villages of Africa in the 1970s, the Ebolavirus was originally believed to be transmitted to people from wild animals. Ebolavirus (EBOV) causes a severe, frequently fatal hemorrhagic syndrome in humans. Each outbreak of the Ebolavirus over the last three decades has perpetuated fear and economi... |
Serosurveys and convalescent plasma in COVID-19 | |
Factors Affecting the Effectiveness of Hospital Incident Command System; Findings from a Systematic Review | OBJECTIVE: To examine all aspects affecting the functioning of the system and the most important factors in its assessment through a systematic review during 1990 to 2017. METHODS: This systematic review of the current literature study was conducted during July 2017, and all articles, books, guidelines, manuals and dis... |
Multivesicular Bodies (MVB) Mimicking SARS-CoV-2 in patients without COVID-19 | |
Mouse hepatitis virus strain — Related patterns of tissue tropism in suckling mice | The pattern of tissue tropism for several prototype and uncharacterized strains of mouse hepatitis virus (MHV) was studied by intranasal inoculation of each virus strain into groups of neonatal Swiss mice under otherwise identical conditions. Mice were killed at intervals up to 18 days after inoculation, and their tiss... |
Viral and bacterial etiology of severe acute respiratory illness among children < 5 years of age without influenza in Niger | BACKGROUND: Globally, pneumonia is the leading cause of morbidity and mortality in children, with the highest burden experienced in sub-Saharan Africa and Asia. However, there is a dearth of information on the etiology of severe acute respiratory illness (SARI) in Africa, including Niger. METHODS: We implemented a retr... |
Newcastle disease virus-based MERS-CoV candidate vaccine elicits high-level and lasting neutralizing antibodies in Bactrian camels | Abstract Middle East respiratory syndrome coronavirus (MERS-CoV), a member of the Coronaviridae family, is the causative pathogen for MERS that is characterized by high fever, pneumonia, acute respiratory distress syndrome (ARDS), as well as extrapulmonary manifestations. Currently, there are no approved treatment regi... |
Redefining Pathways into Acute Rehabilitation during the COVID‐19 Crisis | The coronavirus disease 2019 (COVID‐19) pandemic has necessitated drastic changes across the spectrum of health care, all of which have occurred with unprecedented rapidity. The need to accommodate change on such a large scale has required ingenuity and decisive thinking. The field of physical medicine and rehabilitati... |
Cardiovascular disease potentially contributes to the progression and poor prognosis of COVID-19 | Abstract Background A novel coronavirus severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) caused pneumonia, Coronavirus Disease 2019 (COVID-19), outbroke in Wuhan, China in December 2019, and spread all over the world. Patients with COVID-19 showed huge differences in the hospital stays, progression and pro... |
Plans to Reactivate Gastroenterology Practices Following the COVID-19 Pandemic: A Survey of North American Centers | Abstract: Background and Aims Practices dramatically reduced endoscopy services due to the COVID-19 pandemic. As practices are now considering reintroduction of elective endoscopy, we conducted a survey of North American practices to identify reactivation barriers and strategies. Methods We designed and electronically ... |
Decisions in HCT and wine-making |
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