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f89c62683a21ce90bd00910d53bfbaee3dee520f | fields made her international debut for australia in | fields made her international debut for australia in a test against india in adelaide in february 2006. she was appointed captain of the australian women's cricket team in 2009, replacing the renowned karen rolton. in doing so, she became the first queensland woman to captain the australian team. fields first game as c... | wikipedia |
d714aa061c68c86b49aae5cf4f68c8bddd1a9d0c | fields grew up in queensland playing boy's and | fields grew up in queensland playing boy's and men's cricket before playing women's cricket while at university. she made her debut for the queensland fire in 2000 and captained the team from the 2008–09 season for six years. during her career, she played 165 domestic limited overs matches and 98 women's national crick... | wikipedia |
07fbdfc7a804edf04883344da02d263ee310a485 | a hoberman mechanism, or hoberman linkage, is a | a hoberman mechanism, or hoberman linkage, is a deployable mechanism that turns linear motion into radial motion. the hoberman mechanism is made of two angulated ridged bars connected at a central point by a revolute joint, making it move much like a scissor mechanism. multiple of these linkages can be joined together ... | wikipedia |
42ecc8755c9816d207eb2eb81e569e133db5a023 | the hoberman mechanism has also been used in | the hoberman mechanism has also been used in larger scale architectural projects. one of these structures is the hoberman arch featured the 2002 winter olympics in utah. the arch was designed by chuck hoberman; it was built to open and close using many interlocked hoberman mechanisms, acting as a mechanical curtain on ... | wikipedia |
45917921082c1514c22ca50cfa541491a94ef20a | the most commonly seen form of the hoberman | the most commonly seen form of the hoberman mechanism is in the toy made by chuck hoberman called the mega sphere or hoberman sphere. the mega sphere is a plastic, sphere shaped toy that expands and retracts as it is pushed and pulled on. the toy is made of six full rings of hoberman mechanisms that are all connected t... | wikipedia |
94eb724ca87b6ef96f0a2139a950ff5b8585b13d | the hoberman mechanism is featured in works of | the hoberman mechanism is featured in works of art, mostly made by artist and inventor of the hoberman mechanism, chuck hoberman. structures designed by chuck hoberman that included the hoberman mechanism were featured in the elaine dannheisser projects series from moma. a hoberman sphere also was on display at the mom... | wikipedia |
8ff5cfe2486e4d99cd2bff62905057322371fe79 | the mobility formula for a single degree of | the mobility formula for a single degree of freedom m = 3(n - 1) - 2j, where m is the degrees of freedom, n is the number of moving elements, and j is the number of joints, predicts that a hoberman mechanism of 12 bars and 18 joints would have -3 degrees of freedom. that makes the hoberman mechanism a over-constrained ... | wikipedia |
27da57a7a9bb1129fab7fb02613303750fe23fc5 | a pair of prrp linkages that share a | a pair of prrp linkages that share a coupler curve at a common coupler point have a single degree of freedom, which is why the hoberman mechanism has a single degree of freedom. the motion that the hoberman mechanism produces is radial motion, even though it looks like linear motion, because the motion follows the coup... | wikipedia |
3e0d6e9a4a019d4a0e239cf620c499424e5299e9 | for parameters {r,r,α}, this equation of the coupler | for parameters {r,r,α}, this equation of the coupler curve follows the equation for a straight line (y=mx). because the two angulated rods that make up a hoberman mechanism are identical, they have the same r and r values and thus the same coupler curve. | wikipedia |
f98206dc42cafd934116ff12a347bf33b3b8f2d0 | the hoberman mechanism is a single degree of | the hoberman mechanism is a single degree of freedom structure meaning that the system can be driven with a single actuator. the mechanism is made of two identical angulated rods joined together by a central revolute pivot and four end pivots constrained to move along a single line. because the four end pivots are rest... | wikipedia |
cb8e02459402d531c1c0b4db44262486678b8880 | the hoberman mechanism is made of two identical | the hoberman mechanism is made of two identical angulated rods joined together at their bends by one central revolute joint. these mechanisms can be linked by connecting the ends of the pairs together with two more revolute joints. due to the mechanism's design, however, the revolute joints act as if they are prismatic... | wikipedia |
32a6cc66f8e209a470b317e77913fc0e67349e38 | the hoberman mechanism originates from the idea of | the hoberman mechanism originates from the idea of making something bigger become smaller. chuck hoberman, a fine arts graduate from cooper union, realized that his lack in knowledge of engineering was holding him back from creating the things he could picture in his head. he enrolled in columbia university to get a ma... | wikipedia |
cc75dadd35390bb0395fd5e67e4b25e7c1643c67 | the hoberman mechanism is made of two angulated | the hoberman mechanism is made of two angulated ridged bars connected at a central point by a revolute joint, making it move much like a scissor mechanism. multiple of these linkages can be joined together at the ends of the angulated bars by more revolute joints, expanding radially to make circle shaped mechanisms. th... | wikipedia |
3c1e94c7d6eb4ad7d90a275c5f48c3114480d464 | once the english football league had been resumed | once the english football league had been resumed kirton lead stoke to their first title challenge in 1946–47, described as the 'heartbeat of the side' kirton's stoke lost their must win match against sheffield united and missed out on the grand prize. stoke recorded record profits that season but little of it filtered... | wikipedia |
cc120dbcd3ebe91e7bedef0c23ed0fd47666d210 | kirton was born in aberdeen and played for | kirton was born in aberdeen and played for st marchers and banks o' dee, winning several scottish schoolboy cap. stoke city 's scottish based scouts recommend him to manager bob mcgrory who signed him in the summer of 1935 and he made a number of appearances as cover for frank soo over the following two seasons. kirton... | wikipedia |
f9246ffebde9579ff163fee10c4d53ce2998976e | john kirton (4 march 1916 – 12 march | john kirton (4 march 1916 – 12 march 1996) was a scottish footballer who played in the english football league for bradford city and stoke city. he made 249 appearances for stoke. | wikipedia |
88cea807c0389a330f0710de69813ad09ab2401c | the nac also worked with darpa on a | the nac also worked with darpa on a network based on the arpanet for military use. the analysis they ran and designs they submitted led to the creation of the project autodin ii which never was realized. it was instead replaced by the defense data network which instead of being separated from arpanet like autodin, used... | wikipedia |
dc8f1c926c1bdf326b2db64f0a5dedd4657dae5e | after finishing his project at the oep, in | after finishing his project at the oep, in 1969, howard frank and dave rosenbaum created the network analysis corporation in an effort to solve similar issues than the ones encountered while working at the oep. dr frank was contacted by lawrence roberts to work on the topological design of the arpanet. the nac, with ho... | wikipedia |
17ce4f0e56da0be20aa089056fce0e3122f0ba94 | after being noticed by a white house official | after being noticed by a white house official at a talk on his breakthrough on paul baran 's work, howard frank was invited to work at the office of emergency preparedness as a consultant. the project he worked on was a proof of concept that an office of analytic planning could have its use in the white house. the grou... | wikipedia |
37ae085063659527feedb1327fc68a6dd3b09a60 | while writing his phd, howard frank stumbled on | while writing his phd, howard frank stumbled on a paper published in the journal of mathematical biophysics on how cells reacted to radiation. he noticed that the mathematical model developed in that research could be applied to work done by paul baran in a series of papers called "on distributed communication". this i... | wikipedia |
aef84e8ef6c1db94576f99453ded81ec92e1e225 | his thesis: "optimum locations on a graph with | his thesis: "optimum locations on a graph with probabilistic demands" which he described as "built on probabilistic graphs of some applications and it was statistical communication type theory, sort of an extension of the von neumann work" was completed in 1965. dr frank was hired as assistant professor of engineering ... | wikipedia |
720d2cb268c550170c754e6b8decb6b6ca12529e | howard frank was an academic from 1965, the | howard frank was an academic from 1965, the year he finished his phd, to 1968 before working for the oep as a consultant. he then went on to found the network analysis corporation a year later along with a business associate. after selling nac to contel corporation, he created network management incorporated in 1986. h... | wikipedia |
48c98fec4f58e85ee201abe4a702da3d8e845c95 | a capacitive humidity sensor detects humidity based on | a capacitive humidity sensor detects humidity based on a change of capacitance between two detection electrodes provided on a semiconductor substrate. the capacitance type humidity sensor detects humidity by measuring the change in the electrostatic capacity of an element corresponding to the ambient humidity. a resist... | wikipedia |
bfa69a15e62c6714e2bcc3e4d9e1b024afc37353 | a humistor has a ceramic composition comprising at | a humistor has a ceramic composition comprising at least one component having a spinel type cubic symmetry selected from the group consisting chromates, stannic or titan oxides of different metals like mgcr o, fecr o, nicr o, cocr o, mncr o, cucr o, mg tio, zn tio, mg sno and zn sno, and, if desired, at least one compo... | wikipedia |
fd654b0365ff85525d76ac0a6df5aacd66941cd2 | hypogymnia congesta is a rare species of foliose | hypogymnia congesta is a rare species of foliose lichen in the family parmeliaceae. found in china, it was formally described as a new species in 2003. the lichen grows on the bark and wood of conifers and bamboo. hypogymnia congesta has a brown to brownish-grey foliose thallus measuring up to 8 cm (3.1 in) long or bro... | wikipedia |
efe0db9a4a1e2f8656a6ad038ab15487c71bfcdd | hypogymnia congesta is unique within its genus for | hypogymnia congesta is unique within its genus for containing virensic acid as a major constituent. virensic acid produces pale violet-gray spots in thin-layer chromatography, with specific retardation factor (rf) values that help identify this unique chemical constituent. other chemical components include atranorin an... | wikipedia |
9f520a491335069232a8d52fc8e3eab78d1bf88f | this lichen species lacks soredia and isidia, but | this lichen species lacks soredia and isidia, but often has lobules. apothecia are common, measuring up to 6 mm in diameter. the ascospores are 7.0–8.0 by 5.0–5.5 μm in size, and pycnidia are also common. spermatia are rod-shaped to weakly bifusiform, with dimensions of 5.0–6.0 by 0.8–1.1 μm. | wikipedia |
f0fb571f1a999acfb46f356443d57670d60b0b16 | the thallus of hypogymnia congest is appressed to | the thallus of hypogymnia congest is appressed to somewhat erect and can reach up to 8 cm (3.1 in) in width or length. it has a cartilaginous texture with variable branching patterns, and the lobes are typically 1.7–3.5 mm wide. the upper surface is smooth to weakly rugose and varies in colour from brown to brownish-gr... | wikipedia |
23ae304405b846883c5cad8b23a874fd297a4175 | hypogymnia congesta was first formally described by lichenologists | hypogymnia congesta was first formally described by lichenologists bruce mccune and chicita f. culberson in 2003. the type specimen was collected near wei den village, behind lou ma deng mountain in wei xi county (yunnan province) at an elevation of 3,000 m (9,800 ft). | wikipedia |
4672ebba7ffb05c2328cbc2c29b9d185b15a31ed | hypogymnia congesta is a rare species of foliose | hypogymnia congesta is a rare species of foliose lichen in the family parmeliaceae. found in china, it was formally described as a new species in 2003. the lichen grows on the bark and wood of conifers and bamboo. hypogymnia congesta has a brown to brownish-grey foliose thallus measuring up to 8 cm (3.1 in) long or bro... | wikipedia |
996e0ec74e27009466ea77225d496634adf68dcf | 2005 - champion - superbikes 1000cc 2006 - | 2005 - champion - superbikes 1000cc 2006 - champion - supersport 600cc 2008 - champion - supersport 600cc 2009 - 3rd - superbikes 1000cc 2010 - 2nd - superbikes 1000cc | wikipedia |
16f4788eda88d3e703b6b075b2e3ea2e531a40d2 | 1998 - champion - honda cbr600 trophy 1999 | 1998 - champion - honda cbr600 trophy 1999 - 5th - supersport 600cc 2000 - 6th - supersport 600cc 2001 - vice-champion - honda cbr600 trophy 2002 - 6th - superstock 1000cc | wikipedia |
321a0cbf885563394d391322bddd171ec94b9826 | 2009 - 3rd - supersport 600cc 2008 - | 2009 - 3rd - supersport 600cc 2008 - 3rd - supersport 600cc 2007 - 4th - supersport 600cc 2005 - 4th - supersport 600cc 2003 - 5th - supersport 600cc | wikipedia |
2d5d7f60eb1517d8435c837773ed7843f05132c1 | 2007 - champion superproduction class - 5th overall | 2007 - champion superproduction class - 5th overall 2007 - le mans 24h - 5th superproduction class - 15th overall 2007 - 6h albacete - winner superproduction class - 8th overall 2007 - 24h orschesleben - 3rd superproduction class - 10th overall 2007 - 8h suzuka - winner superproduction class - 14th overall 2007 - 8h qa... | wikipedia |
963de65054ba9b9d180db8b28b6e6316e789bce9 | helen tracy parsons was an american biochemist and | helen tracy parsons was an american biochemist and nutritionist chiefly known for her early work in vitamin b. parsons developed an interest in biochemistry and nutrition at the university of wisconsin-madision, where she was a graduate student under elmer mccollum. parsons spent most of her own scientific career at th... | wikipedia |
77b13b737d3d5f608129face86fda6b09e145d66 | parsons retired from the university of wisconsin-madison in | parsons retired from the university of wisconsin-madison in 1956 at the age of 70. she remained active in the american institute of nutrition, the american society of biological chemists, the american dietetics association, and the american home economics association. she was 1 of 112 charter members of the american in... | wikipedia |
0b33c7ea62c257816c1efd0ed847293d9089aaf6 | although the yeast company she was working for | although the yeast company she was working for was not happy with the results, they allowed parsons to publish her findings. some of her colleagues were not as fortunate - in her oral history parsons recalls some of their research being suppressed by the larger yeast companies and their papers cancelled for publication... | wikipedia |
00112c39b23e6cdf81f453dbfe1fd906a4ea3510 | parsons' later career revolved around thiamine depletion by | parsons' later career revolved around thiamine depletion by live yeast. in the late 1930s and 1940s, it was popular to drink live yeast cocktails. many yeast companies marketed the mixtures as a good source of nutrients and proteins. however, after talking with her colleagues, parsons began to question validity of the ... | wikipedia |
6fd04238b82c7e98fc3927fb26c05ef015a7a065 | at the time, parsons' egg-white results were controversial | at the time, parsons' egg-white results were controversial within the egg and poultry industry. she recalls being "insulted at the time any of reports" were given at meetings and her results were often called into question by those involved with the industries. | wikipedia |
5171e792cdae4b00888f8d890a8087da8eb35f94 | "it was you, my dear doctor parsons, who | "it was you, my dear doctor parsons, who gave me the best stimulus to unravel the difficult problem of egg-white toxicity and biotin deficiency. your excellent and classical experiments on the identification of bound biotin in the feces of rats fed raw egg-white opened the way to solve the puzzle of egg-white toxicity.... | wikipedia |
4ff83a484818133fe407541b0db283c409461840 | parsons and her group then went on to | parsons and her group then went on to look for foods that could counteract the symptoms of egg-white injury. they found that foods like cooked kidney, cooked liver, yeast, egg yolk, or dried milk contained a 'protective factor' (later found to be biotin) that cured the rats dermatitis and prevented the debilitating eff... | wikipedia |
659317866d5162cff1c725278d8336b1977a2d41 | parsons had noticed during her time at yale | parsons had noticed during her time at yale that rats fed only raw egg-white as their protein diet developed unfavorable physiological effects such as severe dermatitis and neurological dysfunction. if kept on the diet, the rats invariably died after a short period of time. parsons hypothesized that there was an 'anti-... | wikipedia |
f3fa4bc4fac50984fe1e65e7dc3d0bb50c3ec3e5 | parsons returned to the university of wisconsin-madison in | parsons returned to the university of wisconsin-madison in 1928 as an associate professor with an annual salary of $3600 and research funding from the university for her own laboratory. there, she was able to expand work done during her doctoral period and perform experiments critical to the discovery of biotin and avi... | wikipedia |
14ed12471b9c2afcf2df65a661d0de46ddb10b82 | around 1927, parsons went to obtain her ph.d. | around 1927, parsons went to obtain her ph.d. under the direction of lafayette mendel, a biochemical nutritionist working out of the yale physiological chemistry laboratory. in parsons’ second year there, she was awarded the mary pemberton nourse fellowship from the american association of university women. her thesis ... | wikipedia |
0da4df5df20e6f00b8efa1950e2e2f203afdc578 | during this time and until after the late | during this time and until after the late 1920s, the department of home economics was not allowed to have ph.d. candidates. according to parsons, the home economics department was seen as more of a trade school, one where "people did cooking and sewing", and the administration did not want the university "smirched with... | wikipedia |
5aefd782107ce9369d34f8d55971231ccca4c93b | in 1917, mccollum moved to head the biochemistry | in 1917, mccollum moved to head the biochemistry department at the newly established johns hopkins school of hygiene and public health, where parsons chose to follow. working in mccollum's lab, parsons had access to the nation's first colony of white rats for use in nutrition experiments. at johns hopkins, parsons work... | wikipedia |
6c82e004e0d05461328c0a58172658fca882d8ff | after another brief teaching job in oklahoma, parsons | after another brief teaching job in oklahoma, parsons met abby marlatt, head of the home economics department at the university of wisconsin-madison, at a dinner party in 1913. marlatt offered her an assistant job at the university of wisconsin-madison where parsons was intended to be the “bridge between science and ho... | wikipedia |
02f628b1b649f24c5b95df2347d5cbe5fb47c335 | at five years old parsons began attending the | at five years old parsons began attending the second ward school in arkansas city, where her aunt was the principal. she moved with her aunt and uncle to alabama, where she attended a co-ed military high school. parsons returned to arkansas city at age sixteen to teach at a country school. after several years of teachi... | wikipedia |
7c0e97de122210543517c82dbcc0e3ef08213f50 | helen tracy parsons was born on march 26, | helen tracy parsons was born on march 26, 1886, in arkansas city, kansas. her father was a physician who came from a pioneer family in indiana and her mother was born at a mission house to mohegan native americans in new england. both her mother's and father's family believed in education and encouraged scholarly think... | wikipedia |
e10e1f5895a45e2d88e2ac6604571970c32ab50c | helen tracy parsons (march 26, 1886 – december | helen tracy parsons (march 26, 1886 – december 30, 1977) was an american biochemist and nutritionist chiefly known for her early work in vitamin b. parsons developed an interest in biochemistry and nutrition at the university of wisconsin-madision, where she was a graduate student under elmer mccollum. parsons spent mo... | wikipedia |
540e94cf33bc1a55e5b5cc7922b9088b950c8ff7 | hasan ali oglu seyidov was an azerbaijani politician, | hasan ali oglu seyidov was an azerbaijani politician, scientist, chairman of the baku regional executive committee, division chairman of the society of chemists named after d. i. mendeleev and azerbaijan ssr minister of agriculture. | wikipedia |
17999a3fbcf32baca8e14250b95630ec8636ea52 | seyidov was born in 1908 in erivan governorate. | seyidov was born in 1908 in erivan governorate. in 1928, he graduated from the azerbaijan agricultural institute, and in 1931-1934 he received doctoral studies at the moscow all-union scientific-research fertilizer and agro-soil science institute. from 1937 to 1962, he worked as the director of the azerbaijan agricultu... | wikipedia |
f3ee5acbc9644e8c82099f5380b9c95008d5e431 | hasan ali oglu seyidov (azerbaijani: həsən Əli oğlu | hasan ali oglu seyidov (azerbaijani: həsən Əli oğlu seyidov, b. 1908, erivan, erivan governorate - d. 8 june 1999, baku) was an azerbaijani politician, scientist, chairman of the baku regional executive committee, division chairman of the society of chemists named after d. i. mendeleev and azerbaijan ssr minister of ag... | wikipedia |
4a65a8b077f6629bbbbeb01695c143dbcf862de3 | james gillen robertson is a scottish former professional | james gillen robertson is a scottish former professional footballer who played as a winger for cowdenbeath, st mirren, tottenham hotspur, arsenal, ipswich town, stoke city, seattle sounders, walsall and crewe alexandra. he was capped once for scotland. | wikipedia |
05ce95772139fae4258749f69f3f7763a9be858a | robertson then joined up with ipswich town in | robertson then joined up with ipswich town in march 1970 for £50,000. at portman road he became a vital member of bobby robson 's squad as ipswich ensured survival in 1969–70 and 1970–71. during the 1971–72 season robertson helped the club move up to a mid-table position. in july 1972 robertson joined stoke city for a ... | wikipedia |
675c2befd4fb463e9f64cef924d45718d60e4612 | he went on to join spurs' rivals arsenal | he went on to join spurs' rivals arsenal in october 1968, in a straight swap for david jenkins, making him one of the few players to play for both clubs. robertson made his debut for arsenal in a goalless draw against west ham united in october 1968. robertson played 19 league matches in the 1968–69 season. the followi... | wikipedia |
7fa32611c41f66d000b8c39eddb12319092945b4 | robertson was born in cardonald, glasgow, and began | robertson was born in cardonald, glasgow, and began his career playing as a right winger at english club middlesbrough. he was not offered a professional contract at middlesbrough, so returned to scotland and joined up with cowdenbeath. after his stint there he signed for st mirren in 1962. with the "buddies", robertso... | wikipedia |
aa78481ec27b16954973cc9f989f93a0773deb3a | james gillen robertson (born 17 december 1944) is | james gillen robertson (born 17 december 1944) is a scottish former professional footballer who played as a winger for cowdenbeath, st mirren, tottenham hotspur, arsenal, ipswich town, stoke city, seattle sounders, walsall and crewe alexandra. he was capped once for scotland. | wikipedia |
de66b9a9db197fb5edbd63482d8fbf2dde40fb71 | john cromwell mather is an american astrophysicist, cosmologist | john cromwell mather is an american astrophysicist, cosmologist and nobel prize in physics laureate for his work on the cosmic background explorer satellite (cobe) with george smoot. this work helped cement the big-bang theory of the universe. according to the nobel prize committee, "the cobe-project can also be regard... | wikipedia |
fe54223729a10f72d3102d73a67f9a8ae262ffa1 | mather is one of the 20 american recipients | mather is one of the 20 american recipients of the nobel prize in physics to sign a letter addressed to president george w. bush in may 2008, urging him to "reverse the damage done to basic science research in the fiscal year 2008 omnibus appropriations bill" by requesting additional emergency funding for the departmen... | wikipedia |
d893ecb826a592dc4816e3ea1591667e062c23c0 | mather is a senior astrophysicist at the nasa | mather is a senior astrophysicist at the nasa goddard space flight center (gsfc) in maryland and adjunct professor of physics at the university of maryland college of computer, mathematical, and natural sciences. in 2007, time magazine listed mather among the 100 most influential people in the world. in october 2012, h... | wikipedia |
6edf47f67e45d0efadbfeb14d8ce440050282d90 | john cromwell mather (born august 7, 1946, roanoke, | john cromwell mather (born august 7, 1946, roanoke, virginia) is an american astrophysicist, cosmologist and nobel prize in physics laureate for his work on the cosmic background explorer satellite (cobe) with george smoot. | wikipedia |
18d7dd8c4c91d215bcefd5818ccce33b097dc1b0 | hubert ('jim') markl is arguably the most influential | hubert ('jim') markl is arguably the most influential figure in european science policy and a key person influencing the relationship between science and society. he has uniquely served as president of the deutsche forschungsgemeinschaft and the max planck gesellschaft. in these roles he has been an outstanding and bol... | wikipedia |
e7210e513d7e0911f00900e0fe988b3f03e8f73d | he received the lorenz oken medal from the | he received the lorenz oken medal from the society of german natural scientists and doctors in 1984, the karl vossler prize in 1985, the arthur burkhardt prize in 1989, the karl winnacker prize in 1991, and the ernst robert curtius prize in 1995, the bundesverdienstkreuz (officially verdienstorden der bundesrepublik de... | wikipedia |
56606edb956a2db3f902de10774652cd5b4b7a4e | from 1977 to 1983, he was vice president | from 1977 to 1983, he was vice president of the deutsche forschungsgemeinschaft (dfg) and from 1986 to 1991, he was president of the dfg. in 1993, he became president of the newly founded berlin-brandenburg academy of sciences and humanities (berlin-brandenburgische akademie der wissenschaften). from 1996 to 2002, he w... | wikipedia |
d187bddc7e9713863ff56b18ac7c2d9726a04f5e | markl was born on 17 august 1938 in | markl was born on 17 august 1938 in regensburg, germany. he studied biology, chemistry and geography at the ludwig maximilian university of munich. he completed his ph.d. in zoology from the ludwig maximilian university of munich in 1962. he did research internships at harvard university and rockefeller university in 1... | wikipedia |
0a51ccb40a52812743817416c524e3616b5ef79e | heinz (heinrich) ulrich feldmann is a german-american virologist | heinz (heinrich) ulrich feldmann is a german-american virologist who currently serves as the chief of the laboratory of virology at rocky mountain laboratories, niaid and heads the disease modelling and transmission section. his research focuses on highly pathogenic viruses that require strict biocontainment, including... | wikipedia |
68ad35d46226fec6bb0c5a71d0cf70fedfc6d188 | from 1999-2008, he served as the chief of | from 1999-2008, he served as the chief of the special pathogens branch at the national microbiology laboratory at phac. in 2008, he began his tenure as the chief of the laboratory of virology at rocky mountain laboratories at niaid. | wikipedia |
c34d1d2f0f30f06c48a07088b6c26f67858f6e05 | heinz received his md from the university of | heinz received his md from the university of marburg in 1987 and his phd in 1988. his doctoral thesis focused on the structural relationship between alpha-influenzavirus serotype hemagglutinin 10 in mammals and avians. he conducted joint postdoctoral research at the university of marburg and the cdc special pathogens b... | wikipedia |
0a51ccb40a52812743817416c524e3616b5ef79e | heinz (heinrich) ulrich feldmann is a german-american virologist | heinz (heinrich) ulrich feldmann is a german-american virologist who currently serves as the chief of the laboratory of virology at rocky mountain laboratories, niaid and heads the disease modelling and transmission section. his research focuses on highly pathogenic viruses that require strict biocontainment, including... | wikipedia |
a5ebf869aebcc89648c5178e602fb34fa0b4e7d4 | a hoogsteen base pair is a variation of | a hoogsteen base pair is a variation of base-pairing in nucleic acids such as the a•t pair. in this manner, two nucleobases, one on each strand, can be held together by hydrogen bonds in the major groove. a hoogsteen base pair applies the n7 position of the purine base and c6 amino group, which bind the watson–crick (n... | wikipedia |
a9cff486ebd8f763b32fd3c724bf378faf7dcf11 | hoogsteen pairs also allows formation of secondary structures | hoogsteen pairs also allows formation of secondary structures of single stranded dna and rna g-rich called g-quadruplexes (g4-dna and g4-rna). evidence exists for both in vitro and in vivo formation of g4s. genomic g4s have been suggested to regulate gene transcription and at the rna level inhibit protein synthesis thr... | wikipedia |
e18c0bf8aafb3b6fbf0d6fedd5c15c9a0bc86ab7 | this non-watson–crick base-pairing allows the third strands to | this non-watson–crick base-pairing allows the third strands to wind around the duplexes, which are assembled in the watson–crick pattern, and form triple-stranded helices such as (poly(da)2poly(dt)) and (poly(rg)2poly(rc)). it can be also seen in three-dimensional structures of transfer rna, as t54a58 and u8a14. | wikipedia |
0063c2c2de2dd28dab56111dc793be784de9d86d | as distortions in the double helix are themselves | as distortions in the double helix are themselves are dependent on base sequence, proteins are able to recognize dna in a manner similar to the way that they recognize other proteins and small ligand molecules, i.e. via geometric shape (instead of the specific sequence). for example, stretches of a and t bases can lead... | wikipedia |
3ff62a9e0137d9883fdcdaf12d9cacc643b2ce11 | dna has many features that allow its sequence-specific | dna has many features that allow its sequence-specific recognition by proteins. this recognition was originally thought to primarily involve specific hydrogen-bonding interactions between amino-acid side chains and bases. but it soon became clear that there was no identifiable one-to-one correspondence — that is, there... | wikipedia |
f3e13a4be180c9937c725ed14bb406b16aefd8a8 | in some dna sequences, especially ca and ta | in some dna sequences, especially ca and ta dinucleotides, hoogsteen base pairs exist as transient entities that are present in thermal equilibrium with standard watson–crick base pairs. the detection of the transient species required the use of nmr relaxation dispersion spectroscopy applied to macromolecules. | wikipedia |
ebc35a87b1841bbd3c79428da7bac752f85dea0f | hoogsteen pairs have quite different properties from watson–crick | hoogsteen pairs have quite different properties from watson–crick base pairs. the angle between the two glycosidic bonds (ca. 80° in the a t pair) is larger and the c1 ′ – c1 ′ distance (ca. 860 pm or 8.6 Å) is smaller than in the regular geometry. in some cases, called reversed hoogsteen base pair s, one base is rotat... | wikipedia |
a6f4655585af323609acc29a1db0c49af70a70c8 | ten years after james watson and francis crick | ten years after james watson and francis crick published their model of the dna double helix, karst hoogsteen reported a crystal structure of a complex in which analogues of a and t formed a base pair that had a different geometry from that described by watson and crick. similarly, an alternative base-pairing geometry ... | wikipedia |
a95768b8350a91c6f4b60ca81c00c4868c53ecc0 | a hoogsteen base pair is a variation of | a hoogsteen base pair is a variation of base-pairing in nucleic acids such as the at pair. in this manner, two nucleobases, one on each strand, can be held together by hydrogen bonds in the major groove. a hoogsteen base pair applies the n7 position of the purine base (as a hydrogen bond acceptor) and c6 amino group (a... | wikipedia |
9094431a2fb63191f51b649876060549676edced | iron–sulfur proteins are proteins characterized by the presence | iron–sulfur proteins are proteins characterized by the presence of iron–sulfur clusters containing sulfide-linked di-, tri-, and tetrairon centers in variable oxidation states. iron–sulfur clusters are found in a variety of metalloproteins, such as the ferredoxins, as well as nadh dehydrogenase, hydrogenases, coenzyme ... | wikipedia |
c054009ba733768d9c5934e174c4ddc50ea9f3d1 | synthetic analogues of the naturally occurring fe–s clusters | synthetic analogues of the naturally occurring fe–s clusters were first reported by holm and coworkers. treatment of iron salts with a mixture of thiolates and sulfide affords derivatives such as (et n) fe s (sch ph) ]. | wikipedia |
29c6ce3a6764c24ab3bf1c1b37a9c7d425f44a4c | the yeast isc system is the best described. | the yeast isc system is the best described. several proteins constitute the biosynthetic machinery via the isc pathway. the process occurs in two major steps:(1) the fe/s cluster is assembled on a scaffold protein followed by (2) transfer of the preformed cluster to the recipient proteins.the first step of this process... | wikipedia |
04ae75e6fb431ca6cedada7abdbb86a2fa171744 | the biosynthesis of the fe–s clusters has been | the biosynthesis of the fe–s clusters has been well studied. the biogenesis of iron sulfur clusters has been studied most extensively in the bacteria e. coli and a. vinelandii and yeast s. cerevisiae. at least three different biosynthetic systems have been identified so far, namely nif, suf, and isc systems, which were... | wikipedia |
fe05ba123c30cd630410f8c7c6f32b4e3f45b645 | proteins are also known to contain centres, which | proteins are also known to contain centres, which feature one iron less than the more common cores. three sulfide ions bridge two iron ions each, while the fourth sulfide bridges three iron ions. their formal oxidation states may vary from (all-fe form) to (all-fe form). in a number of iron–sulfur proteins, the cluster... | wikipedia |
2d38fa552d2a6938501a3e9a77bb9fc93b735568 | the second cubane shown here with mixed valence | the second cubane shown here with mixed valence pairs (2 fe3+ and 2 fe2+), has a greater stability from covalent communication and strong covalent delocalization of the “extra” electron from the reduced fe2+ that results in full ferromagnetic coupling. | wikipedia |
2bb079bdb495e025afcadfd3930733cc23017451 | some 4fe–4s clusters bind substrates and are thus | some 4fe–4s clusters bind substrates and are thus classified as enzyme cofactors. in aconitase, the fe–s cluster binds aconitate at the one fe centre that lacks a thiolate ligand. the cluster does not undergo redox, but serves as a lewis acid catalyst to convert citrate to isocitrate. in radical sam enzymes, the cluste... | wikipedia |
3dd41cc7f35350e0d054bbc5096a146ec00e03e2 | in hipip, the cluster shuttles between (fe s) | in hipip, the cluster shuttles between (fe s) and (fe s). the potentials for this redox couple range from 0.4 to 0.1 v. in the bacterial ferredoxins, the pair of oxidation states are (fe s) and (fe s). the potentials for this redox couple range from −0.3 to −0.7 v. the two families of 4fe–4s clusters share the fe s oxi... | wikipedia |
ed946667fc1624150d1a4637fb8e75c66916c086 | a common motif features a four iron ions | a common motif features a four iron ions and four sulfide ions placed at the vertices of a cubane-type cluster. the fe centers are typically further coordinated by cysteinyl ligands. the electron-transfer proteins (ferredoxins) may be further subdivided into low-potential (bacterial-type) and high-potential (hipip) fer... | wikipedia |
98a6f4b5f458015c627250cd72f52fe69a779388 | the rieske proteins contain fe–s clusters that coordinate | the rieske proteins contain fe–s clusters that coordinate as a 2fe–2s structure and can be found in the membrane bound cytochrome bc1 complex iii in the mitochondria of eukaryotes and bacteria. they are also a part of the proteins of the chloroplast such as the cytochrome b f complex in photosynthetic organisms. these ... | wikipedia |
0f19eeee1d1d02e77df6a490afdc69557cd67d81 | the simplest polymetallic system, the cluster, is constituted | the simplest polymetallic system, the cluster, is constituted by two iron ions bridged by two sulfide ions and coordinated by four cysteinyl ligands (in fe s ferredoxins) or by two cysteines and two histidines (in rieske proteins). the oxidized proteins contain two fe ions, whereas the reduced proteins contain one fe a... | wikipedia |
029d8f6b4734ce371933a7d1499ae4a493419ccd | the fe 3d orbital energies follow the "inverted" | the fe 3d orbital energies follow the "inverted" bonding scheme which fortuitously has the fe d-orbitals closely matched in energy with the sulfur 3p orbitals, giving high covalency in the resulting bonding molecular orbital. this high covalency lowers the inner sphere reorganization energy and ultimately contributes t... | wikipedia |
c4cb034d6656282451467d352c33e362343d851c | external water molecules positioned close to the iron-sulfur | external water molecules positioned close to the iron-sulfur active site reduces covalency; this can be shown by lyophilization experiments where water is removed from the protein. this reduction is because external water hydrogen bonds with cysteine s, decreasing the latter's lone pair electron donation to the fe by p... | wikipedia |
c5bc320503adfca343cd6767d7f7be904543a3ed | fe -sr bonds have unusually high covalency which | fe -sr bonds have unusually high covalency which is expected. when comparing the covalency of fe with the covalency of fe, fe has almost double the covalency of fe (20% to 38.4%). fe is also much more stabilized than fe. hard ions like fe normally have low covalency because of the energy mismatch of the metal lowest un... | wikipedia |
fa3317bca53e3c48361821375b0e27fafe2b4881 | iron-sulfur proteins are involved in various biological electron | iron-sulfur proteins are involved in various biological electron transport processes, such as photosynthesis and cellular respiration, which require rapid electron transfer to sustain the energy or biochemical needs of the organism. to serve their various biological roles, iron-sulfur proteins effect rapid electron tra... | wikipedia |
a8a182889640cd52789b98a2661267558feef33a | in almost all fe–s proteins, the fe centers | in almost all fe–s proteins, the fe centers are tetrahedral and the terminal ligands are thiolato sulfur centers from cysteinyl residues. the sulfide groups are either two- or three-coordinated. three distinct kinds of fe–s clusters with these features are most common. | wikipedia |
31ba0babbfc12e079d507fae132cd147e2994fe6 | iron–sulfur proteins are proteins characterized by the presence | iron–sulfur proteins are proteins characterized by the presence of iron–sulfur clusters containing sulfide -linked di-, tri-, and tetrairon centers in variable oxidation states. iron–sulfur clusters are found in a variety of metalloproteins, such as the ferredoxins, as well as nadh dehydrogenase, hydrogenases, coenzyme... | wikipedia |
d4b1580a0926acbceb418c3d9762d13c98c9d47e | jan j. trąbka was a full professor of | jan j. trąbka was a full professor of neurological and computer sciences at the jagiellonian university medical college. he went to the faculty of medicine of the kraków academy of medicine and received his md from the academy of medicine, kraków in 1955 and defended his phd in 1961, thesis entitled "bioelectric activi... | wikipedia |
8553e95325e9f942edf741492d3cab84a8b120f1 | jan j. trąbka (21 june 1931 – 27 | jan j. trąbka (21 june 1931 – 27 july 2012) was a full professor of neurological and computer sciences at the jagiellonian university medical college. he went to the faculty of medicine of the kraków academy of medicine and received his md from the academy of medicine, kraków in 1955 and defended his phd in 1961, thesi... | wikipedia |
ee80af852461f7bbd665c8be912c9a752830a363 | in june 2019, ifwat was called up to | in june 2019, ifwat was called up to the 2022 fifa world cup qualification match against timor-leste where he played the entire match in the second leg of the 2022 fifa world cup qualification – afc first round in a 5–1 win. | wikipedia |
d4951b7cbdccfdc717ae19abfb4ece86c2f99f12 | mohd ifwat akmal bin chek kassim (born 10 | mohd ifwat akmal bin chek kassim (born 10 august 1996) is a malaysian professional footballer who plays as goalkeeper for malaysia super league club kedah darul aman and the malaysia national team. | wikipedia |
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