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66539386639c2ef44245400c08de8e21fa9acfc3 | between 1937 and 1948, mcalinden made 5 appearances | between 1937 and 1948, mcalinden made 5 appearances for the ifa xi, making his international debut in a 1–1 draw with scotland at pittodrie stadium on 10 november 1937. his ifa xi appearances also include the 8–4 defeat against a combined services xi at windsor park on 9 september 1944. this team was basically a great ... | wikipedia |
935d31cb67dc21545d62b8f01dbff60992ea8298 | when mcalinden began his international career in 1937 | when mcalinden began his international career in 1937 there were in effect, two ireland teams, chosen by two rival associations. both associations, the northern ireland – based ifa and the irish free state – based fai claimed jurisdiction over the whole of ireland and selected players from the whole island. as a result... | wikipedia |
7a058280861098daf3ecf64accbc045fd3f6b8dd | in 1948 southend united signed mcalinden from stoke | in 1948 southend united signed mcalinden from stoke city for a fee of £8,000. he continued to play for united until 1954 and during his time with the club he served as club captain. he also became something of a cult hero among the club's fans and is remembered as being possibly the best player ever to play for the clu... | wikipedia |
b8df4a4290bbf23a5eae38d5e1b59ad6fae75e53 | mcalinden joined stoke city in september 1947 for | mcalinden joined stoke city in september 1947 for a then club record fee of £7,000. he became regular inside forward under manager bob mcgrory in 1947–48 playing in 33 matches scoring just twice against aston villa and huddersfield town. his lack of goals saw him fall out of favour at the victoria ground and he was sol... | wikipedia |
0a83d7ef0a577ecde5daf854bad13bc25e5b9f07 | following the end of his second spell with | following the end of his second spell with belfast celtic and before he rejoined portsmouth, mcalinden signed for shamrock rovers in september 1945. he made his debut against shelbourne at milltown on 16 september. while playing for rovers his teammates included paddy coad, peter farrell and tommy eglington. during his... | wikipedia |
ab225588e9f7aeb708f4a1702f8c93cbbb1d880a | in december 1938 mcalinden signed for portsmouth for | in december 1938 mcalinden signed for portsmouth for a fee of £7.500. he made his debut for the club against chelsea and went onto became a regular in the side. within six months of his arrival at the club, he helped them win the 1939 fa cup final, beating wolves 4–1. after the outbreak of the second world war, he play... | wikipedia |
90852cc8318f13c3fa37766cac6c3c82e32e302a | in 1934, aged 16, mcalinden was playing for | in 1934, aged 16, mcalinden was playing for glentoran reserves, when after a game against their reserves, he was offered a professional contract by belfast celtic. mcalinden, together with jackie vernon, tommy breen, billy mcmillan and charlie tully, subsequently became a prominent member of the celtic team managed by ... | wikipedia |
9f9717aaa212ba9c84c6d61acb1231f2e394728d | james mcalinden (27 december 1917 – 15 november | james mcalinden (27 december 1917 – 15 november 1993) was an irish footballer who played as a forward for several clubs, most notably, belfast celtic, portsmouth, shamrock rovers and southend united. as an international, mcalinden also played for both ireland teams – the ifa xi and the fai xi. after retiring as a playe... | wikipedia |
1f3ebe929ba13754571704586dd16b3109f5606e | gpsr is a geo routing method, which means | gpsr is a geo routing method, which means that data packages are not sent to a special receiver but to coordinates. the packages should be relayed to the node that's geographically closest to the coordinates. this assumes that every node knows its own position. | wikipedia |
f7960edcdc80c9f22d749513d0b8d9ce5a0be9ee | graeme bonham-carter is a uk-born canadian mathematical geologist. | graeme bonham-carter is a uk-born canadian mathematical geologist. he served as president of the international association for mathematical geosciences (iamg) from 2000 to 2004. he was editor-in-chief of the journal computers & geosciences from 1996 to 2005. he received the william christian krumbein medal in 1998 from... | wikipedia |
daa994e60f6f51409a8c3f7ee8ef9840422996db | graeme bonham-carter (born in 1939) is a uk-born | graeme bonham-carter (born in 1939) is a uk-born canadian mathematical geologist. he served as president of the international association for mathematical geosciences (iamg) from 2000 to 2004. he was editor-in-chief of the journal computers & geosciences from 1996 to 2005. he received the william christian krumbein med... | wikipedia |
ba4627ff4578d1888d48133b51644a5d0bb49609 | hypoxanthine-guanine phosphoribosyltransferase (hgprt) is an enzyme encoded in | hypoxanthine-guanine phosphoribosyltransferase (hgprt) is an enzyme encoded in humans by the hprt1 gene. hgprt is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate. this reaction transfers the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosph... | wikipedia |
ee6c9b5e33fd8bfd82de484c90922772d07a60d7 | hybridomas are immortal (immune to cellular senescence), hgprt | hybridomas are immortal (immune to cellular senescence), hgprt cells that result from fusion of mortal, hgprt plasma cells and immortal, hgprt myeloma cells. they are created to produce monoclonal antibodies in biotechnology. hat medium inhibits de novo synthesis of nucleic acids, killing myeloma cells that cannot swit... | wikipedia |
3fa400985808126463b301e8fb4bc6676a74c574 | comparative homology modelling of this enzyme in l. | comparative homology modelling of this enzyme in l. donovani suggest that among all of the computationally screened compounds, pentamidine, 1,3-dinitro adamantane, acyclovir and analogs of acyclovir had higher binding affinities than the real substrate (guanosine monophosphate). the in silico and in-vitro correlation o... | wikipedia |
68eccdd71eb475d968f60c2d147d74488144aeb1 | hgprtase functions primarily to salvage purines from degraded | hgprtase functions primarily to salvage purines from degraded dna to reintroduce into purine synthetic pathways. in this role, it catalyzes the reaction between guanine and phosphoribosyl pyrophosphate (prpp) to form gmp, or between hypoxanthine and phosphoribosyl pyrophosphate (prpp) to form inosine monophosphate. | wikipedia |
e3f75b3cc1eb2c1ddebbb568e2e44daa70d75dc6 | hgprt is a transferase that catalyzes conversion of | hgprt is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate. this reaction transfers the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate (prpp) to the purine. hgprt plays a central role in the generation of purine nucleotides through the ... | wikipedia |
02ea72165950673feb9aa1a8289b8ab1bacd0eb8 | in fact, magnetostriction is more complex and depends | in fact, magnetostriction is more complex and depends on the direction of the crystal axes. in iron, the axes are the directions of easy magnetization, while there is little magnetization along the directions (unless the magnetization becomes close to the saturation magnetization, leading to the change of the domain or... | wikipedia |
ec6d381f329d2fc81b44a9286e5d3bbfb0ee2398 | where λ s {\displaystyle \lambda _{s}} is the | where λ s {\displaystyle \lambda _{s}} is the magnetostrictive expansion at saturation, and θ {\displaystyle \theta } is the angle between the saturation magnetization and the stress's direction. when λ s {\displaystyle \lambda _{s}} and σ {\displaystyle \sigma } are both positive (like in iron under tension), the ener... | wikipedia |
f1d11c45d2f270b2ca8a30b4c1bde2d451e22ca4 | this means, that when the product σ λ | this means, that when the product σ λ s {\displaystyle \sigma \lambda _{s}} is positive, the flux density b {\displaystyle b} increases under stress. on the other hand, when the product σ λ s {\displaystyle \sigma \lambda _{s}} is negative, the flux density b {\displaystyle b} decreases under stress. this effect was co... | wikipedia |
38ffae4b2ad7414376ac8de79640e54354e120c9 | (d λ d h) σ = (d b | (d λ d h) σ = (d b d σ) h {\displaystyle \left({\frac {d\lambda }{dh}}\right)_{\sigma }=\left({\frac {db}{d\sigma }}\right)_{h}} | wikipedia |
6acd29af962ff35da2c343bb9cab5d83c99aa101 | under a given uni-axial mechanical stress σ {\displaystyle | under a given uni-axial mechanical stress σ {\displaystyle \sigma }, the flux density b {\displaystyle b} for a given magnetizing field strength h {\displaystyle h} may increase or decrease. the way in which a material responds to stresses depends on its saturation magnetostriction λ s {\displaystyle \lambda _{s}}. for... | wikipedia |
14c06d0e4c4235e7148b9855cb241dae802508bf | the magnetostriction λ {\displaystyle \lambda } characterizes the | the magnetostriction λ {\displaystyle \lambda } characterizes the shape change of a ferromagnetic material during magnetization, whereas the inverse magnetostrictive effect characterizes the change of sample magnetization m {\displaystyle m} (for given magnetizing field strength h {\displaystyle h}) when mechanical str... | wikipedia |
44dd135c8a6e662a56a666fc9132312e59bd55ec | he featured in four unofficial matches with the | he featured in four unofficial matches with the belgium national team between 1901 and 1904, in which he represented belgium in friendly cup duels against the netherlands. he scored 12 goals in those 4 caps, resulting in a strike rate of 3 goals per game. | wikipedia |
5dab52d6c887a8d81a5ec2e42ca200ed574ae31b | he was the topscorer in the belgian first | he was the topscorer in the belgian first division in the 1900–01 and 1901–02 seasons, with 26 and 16 goals respectively, with the former tally possible being a record at the time until gustave vanderstappen broke it with 30 goals in the 1903–04 season. | wikipedia |
d55e1ec60b5120c58a9e73369ac084acbf1ecb32 | this series was formerly designed as a line | this series was formerly designed as a line of cabinet-size solutions, prior to the more compact and affordable rack-mount ds6000 series. in 2015 the ds6000 line were discontinued, and the all-flash entry-level ds8882f model was released as a rack-mount successor of ds6000 line. | wikipedia |
62b3eaa17ce698ff4d43835748689818cd3c060b | hokkeguchi station opened on march 3, 1915. the | hokkeguchi station opened on march 3, 1915. the station building and platform were registered by the national government as a national registered tangible cultural property in 2014. the outhouse toilet of the station also received protection as a registered tangible cultural property at the same time. | wikipedia |
a1a3a30c3b8416d5aef35ab2f4ded866632302b0 | hokkeguchi station (法華口駅, hokkeguchi-eki) is a passenger railway | hokkeguchi station (法華口駅, hokkeguchi-eki) is a passenger railway station located in the city of kasai, hyōgo prefecture, japan, operated by the third-sector hōjō railway company. | wikipedia |
14e65bd51e1afcfed611d02bea29866fa866d3bb | kornelia polyak is a professor of medicine at | kornelia polyak is a professor of medicine at harvard medical school and an internationally recognized breast cancer expert. polyak earned her md from albert szent-gyorgyi medical university in szeged, hungary, and her phd from weill cornell graduate school of medical sciences/sloan-kettering cancer center in new york ... | wikipedia |
512eb100b306e56fb77be4a58aacb6bf644e1497 | polyak earned her md from albert szent-gyorgyi medical | polyak earned her md from albert szent-gyorgyi medical university in szeged, hungary, and her phd from weill cornell graduate school of medical sciences / sloan-kettering cancer center in new york city. she then did a fellowship in cancer genetics at johns hopkins oncology center with bert vogelstein and kenneth kinzle... | wikipedia |
62331e3bc336b994ed417ccf00c250b244970095 | hendrik (henk) koppelaar is a dutch computer scientist | hendrik (henk) koppelaar is a dutch computer scientist and emeritus professor at the delft university of technology, knows for his work in knowledge engineering. koppelaar started his studies at the utrecht university in 1971, where he graduated in physics in 1976. in 1981 he started his graduate study at the universit... | wikipedia |
48fddece9ed94083f3dc12df4a6859086546cf7b | early research of koppelaar focussed on automatic recognition | early research of koppelaar focussed on automatic recognition of handprinted characters, where they had developed a method of syntactic pattern recognition using fuzzy set theory. their research had focussed on handwritten capitals. later in the 1980s his research had focussed the application of chaos theory in the soc... | wikipedia |
7bc21bc321020c38fa88b66fd2dc10816d86eecd | koppelaar was appointed professor at the university of | koppelaar was appointed professor at the university of amsterdam in 1986. in 1986 he moved to delft university of technology, where he served as professor of the computer science until 2004. in 1986 he was founder of the dutch artificial intelligence association, which merged into the belgian dutch artificial intellige... | wikipedia |
cb1ac84c33d7868cce8fda9c46d3f11c0c3a54d0 | koppelaar started his studies at the utrecht university | koppelaar started his studies at the utrecht university in 1971, where he graduated in physics in 1976. in 1981 he started his graduate study at the university of amsterdam, where he obtained his phd in computer and information sciences and support services in 1984. under supervision of gideon j. mellenbergh and j.k. d... | wikipedia |
2507a550b998eb6d167046ec1ca3b8cdbba4087b | hilda judith koopman is a linguist who does | hilda judith koopman is a linguist who does research and fieldwork in the areas of syntax and morphology. she is a professor in the department of linguistics at the university of california, los angeles, and is the director of the sswl database. the sswl, which she together with dennis shasha inherited from chris colli... | wikipedia |
c65604ed34a9ad7ce55e0416627ea985ffde7b55 | koopman has been a professor of linguistics at | koopman has been a professor of linguistics at ucla since 1985. she served on the editorial boards of oxford university press (comparative syntax), studies in natural language and linguistic theory, kluwer academic publishers (book series), natural language and linguistic theory, and the journal of comparative germanic... | wikipedia |
5330304b5e227e8f7d11ee9165abdf5a57932548 | hilda koopman is interested in both theoretical linguistics | hilda koopman is interested in both theoretical linguistics and field linguistics. her area of specialization includes linguistic theory, fieldwork, syntax, morphology, comparative syntax as a field linguists, she has worked on various (un(der)described) languages. some of the languages and language family she has work... | wikipedia |
af21269b579746eefed050ca1d673beea75fdd09 | hilda judith koopman is a linguist who does | hilda judith koopman is a linguist who does research and fieldwork in the areas of syntax and morphology. she is a professor in the department of linguistics at the university of california, los angeles, and is the director of the sswl (syntactic and semantic structures of the world's languages) database. the sswl, whi... | wikipedia |
6e5079ee1662dc049eadcc0a8f741182013a41a5 | joseph r. volpicelli is an american psychiatrist, research | joseph r. volpicelli is an american psychiatrist, research scientist, medical academic, and expert in the treatment of addictive disorders. he is professor emeritus, perelman school of medicine at the university of pennsylvania. he is board certified in neurology, psychiatry and addiction psychiatry. he currently is me... | wikipedia |
36cb8b7e21192419096a23b06d63320cb8d572ad | as of may 2023, volpicelli has authored two | as of may 2023, volpicelli has authored two books and over 100 peer-reviewed research publications. in april 2000, volpicelli's first book, recovery options: the complete guide, with maia szalavitz, was released. later, march 2001, volpicelli and co-authors helen pettinati, a.thomas mclellan and charles p. o'brien rele... | wikipedia |
ea8245cdf0c2b15f11bcfdccc5f8cdb690f2277d | this study was published in the archives of | this study was published in the archives of general psychiatry in 1992, by volpicelli with his colleagues al alterman, motoi hayashida, and charles p. o'brien. based on the results of this and another study conducted at yale by stephanie o'mally, in 1994, the fda approved the use of naltrexone to treat alcohol dependen... | wikipedia |
84d44fad597a86adae0f7a96bbb42bc74dac45c5 | based on his early experimental research with an | based on his early experimental research with an animal model of alcohol drinking, he designed and conducted the first clinical trial of naltrexone in the treatment of alcohol dependence. with the support of his mentor, charles p. o'brien, and funding from the u.s. veterans administration substance abuse center in phil... | wikipedia |
26e1a9ba28e0caa45e1129b81c42683cd483c365 | during this time, he also designed a treatment | during this time, he also designed a treatment modality called the brenda approach. each letter in the acronym brenda represents a step in the process. b(biopsychosocial evaluation), r(report findings to patient), e(empathize), n(what are the needs of the patient), d(direct advice), a(assess patient's response to advic... | wikipedia |
a075a58ae701dd8ecee190e5326f78ec8980e0fc | volpicelli attended dickinson college for his undergraduate education | volpicelli attended dickinson college for his undergraduate education where he double majored in biology and psychology. he earned his md and phd degrees from perelman school of medicine at the university of pennsylvania in 1981. following this, he went on to complete a psychiatry residency at hospital of the universit... | wikipedia |
dae33aae28765d0994c7c36f3dad133c0df6135d | joseph r. volpicelli (born june 25, 1953) is | joseph r. volpicelli (born june 25, 1953) is an american psychiatrist, research scientist, medical academic, and expert in the treatment of addictive disorders. he is professor emeritus, perelman school of medicine at the university of pennsylvania. he is board certified in neurology, psychiatry and addiction psychiatr... | wikipedia |
7d7b133c5397e95106efbacb0089f239ad1e20cb | a jumping library clone is composed of two | a jumping library clone is composed of two stretches of dna that are usually located many kilobases away from each other. the stretch of dna located between these two "ends" is deleted by a series of biochemical manipulations carried out at the start of this cloning technique. | wikipedia |
6b03735d93718af26b7dc9b231c9bb85ea8d2491 | in metagenomics, regions of the genomes that are | in metagenomics, regions of the genomes that are shared between strains are typically longer than the reads. this complicates the assembly process and makes reconstructing individual genomes for a species a daunting task. chimeric pairs that are mapped far apart in the genome can facilitate the de novo assembly process... | wikipedia |
0e39f3b8c80a5e690e6a558ed7dc79fa7f2446de | conventional cyto genetic testing cannot offer the gene-level | conventional cyto genetic testing cannot offer the gene-level resolution required to predict the outcome of a pregnancy and whole genome deep sequencing is not practical for routine prenatal diagnosis. whole-genome jumping library could complement conventional prenatal testing. this novel method was successfully applie... | wikipedia |
c6e90f27a53fa071925780342ade069f5b1814f9 | talkowski et al. compared different approaches to detect | talkowski et al. compared different approaches to detect balanced chromosome alterations, and showed that modified jumping library in combination with next generation dna sequencing is an accurate method for mapping chromosomal breakpoints. two varieties of jumping libraries (short-jump libraries and custom barcoded ju... | wikipedia |
c3e5ecae543013daaf6013fa73309a888bf07688 | a jumping library ngs combined approach can be | a jumping library ngs combined approach can be applied to identify such genomic changes. for example, slade et al. applied this method to fine map a de novo balanced translocation in a child with wilms' tumor. for this study, 50 million reads were generated, but only 11.6% of these could be mapped uniquely to the refer... | wikipedia |
3a06f24e1341dcbeda9a005c1f142e38155f92ae | balanced chromosomal rearrangements can have a significant contribution | balanced chromosomal rearrangements can have a significant contribution to diseases, as demonstrated by the studies of leukemia. however, many of them are undetected by chromosomal microarray. karyotyping and fish can identify balanced translocations and inversions but are labor-intensive and provide low resolution (sm... | wikipedia |
c8113f390e9b6f6fbebc970fe1575f0c659e0f40 | in the early days, chromosome walking from genetically | in the early days, chromosome walking from genetically linked dna markers was used to identify and clone disease genes. however, the large molecular distance between known markers and the gene of interest was complicating the cloning process. in 1987, a human chromosome jumping library was constructed to clone the cyst... | wikipedia |
535eb78163d8dba6e762e7c9c6e42399e14604c6 | different assembly tools have been developed to handle | different assembly tools have been developed to handle jumping library data. one example is delly. delly was developed to discover genomic structural variants and "integrates short insert paired-ends, long-range mate-pairs and split-read alignments" to detect rearrangements at sequence level. | wikipedia |
fef0b9438a2041c00dfb1f16327e2249bef25528 | the segments resulting from circularization during constructing jumping | the segments resulting from circularization during constructing jumping library are cleaved, and dna fragments with markers will be enriched and subjected to paired-end sequencing.these dna fragments are sequenced from both ends and generate pairs of reads. the genomic distance between the reads in each pair is approxi... | wikipedia |
40a87ec2cfb38bef957427bfbc37257dfe0ef965 | this library construction process is also similar to | this library construction process is also similar to that of short-jump library except that transfection using the e. coli vector is required for amplification of large (40 kb) dna fragments. in addition, the fosmids can be modified to facilitate the conversion into jumping library compatible with certain next generati... | wikipedia |
df40bfad977db1c9bc8462ee59d2dde8500942c0 | this jumping library uses adaptors containing markers for | this jumping library uses adaptors containing markers for fragment selection in combination with barcodes for multiplexing. the protocol was developed by talkowski et al. and based on mate-pair library preparation for solid sequencing. the selected dna fragment size is 3.5 – 4.5 kb. two adaptors were involved: one cont... | wikipedia |
1a5813ac42bcccb3e2f3b3e53ec8d83a0431f862 | there are two issues related to short-jump libraries. | there are two issues related to short-jump libraries. first, a read can pass through the biotinylated circularization junction and reduce the effective read length. second, reads from non-jumped fragments (i.e. fragments without the circularization junction) are sequenced and reduce genomic coverage. it has been report... | wikipedia |
b3288bf2f7a2c6c86404252a8848f5efbdbfd663 | in a short-jump library, 3 kb genomic dna | in a short-jump library, 3 kb genomic dna fragments are ligated with biotinylate ends and circularized. the circular segments are then sheared into small fragments and the biotinylated fragments are selected by affinity assay for paired-end sequencing. | wikipedia |
55fe00efb0637600a335ee9ce39b600dec43975b | a library is often prepared by random fragmentation | a library is often prepared by random fragmentation of dna and ligation of common adaptor sequences. however, the generated short reads challenge the identification of structural variants, such as indels, translocations, and duplication. large regions of simple repeats can further complicate the alignment. alternativel... | wikipedia |
050c433acd5d41c7265d7ec5681247c409257a44 | second-generation or "next-gen" (ngs) techniques have evolved radically: | second-generation or "next-gen" (ngs) techniques have evolved radically: the sequencing capacity has increased more than ten thousandfold and the cost has dropped by over one million-fold since 2007(national human genome research institute). ngs has revolutionized the genetic field in many ways. | wikipedia |
389c7d9e42a715b14e82bd6d45eaf12f86c80690 | in 1991, zabarovsky et al. proposed a new | in 1991, zabarovsky et al. proposed a new approach for construction of jumping libraries. this approach included the use of two separate λ vectors for library construction, and a partial filling-in reaction that removes the need for a selectable marker. this filling-in reaction worked by destroying the specific cohesiv... | wikipedia |
8a22d32e6d127ecac9f38e940ba4078ad2d6494b | poustka and lehrach suggested that full digestion with | poustka and lehrach suggested that full digestion with rare-cutting restrictions enzymes (such as noti) should be used for the first step of the library construction instead of partial digestion with a frequently cutting restriction enzyme. this would significantly reduce the number of clones from millions to thousands... | wikipedia |
4e44cd4e0283d8468ea73a74c2caecefa985a2e1 | collins and weissman's method described above encountered some | collins and weissman's method described above encountered some early limitations. the main concern was with avoiding non-circularized fragments. two solutions were suggested: either screening junction fragments with a given probe or adding a second size-selection step after the ligation to separate single circular clon... | wikipedia |
3e57c148da85bde7d4dc2fb64665f7ec7ee32ca0 | the original technique of chromosome jumping was developed | the original technique of chromosome jumping was developed in the laboratories of collins and weissman at yale university in new haven, u.s. and the laboratories of poustka and lehrach at the european molecular biology laboratory in heidelberg, germany. | wikipedia |
f206b1c55ae4531cadd92511166276c6879c7d1a | this technique is an extension of "chromosome walking" | this technique is an extension of "chromosome walking" that allows larger "steps" along the chromosome.if steps of length n kb are desired, very high molecular weight dna is necessary. once isolated, it is partially digested with a frequent-cutting restriction enzyme (such as mboi or bamhi). next, obtained fragments ar... | wikipedia |
841a0b4f756d9b0c44ae44f1c4410ffd2ebb4c6b | chromosome jumping (or chromosome hopping) was first described | chromosome jumping (or chromosome hopping) was first described in 1984 by collins and weissman. at the time, cloning techniques allowed for generation of clones of limited size (up to 240kb), and cytogenetic techniques allowed for mapping such clones to a small region of a particular chromosome to a resolution of aroun... | wikipedia |
523ae6488aaa2c86b7d69931584218ce93ba3ec1 | jumping libraries or junction-fragment libraries are collections of | jumping libraries or junction-fragment libraries are collections of genomic dna fragments generated by chromosome jumping. these libraries allow the analysis of large areas of the genome and overcome distance limitations in common cloning techniques.a jumping library clone is composed of two stretches of dna that are u... | wikipedia |
e5426ac13db99ae6bd6f8fc32f5a32c39b72afd3 | igoris pankratjevas is a lithuanian professional football coach | igoris pankratjevas is a lithuanian professional football coach and a former player. he made his debut in the soviet top league in 1983 for fk Žalgiris vilnius. igoris pankratjevas coached several top lithuanian football clubs. in 2010 season he was voted best coach of the year after winning bronze medals with a promot... | wikipedia |
e8b700131e6b0db1b7622a20e5b27dc9eb2d5597 | igoris pankratjevas coached several top lithuanian football clubs. | igoris pankratjevas coached several top lithuanian football clubs. in 2010 season he was voted best coach of the year after winning bronze medals with a promoted fk Žalgiris vilnius side. appointed lithuania assistant coach in march 2012, before taking over as caretaker in september 2013 and then giving a permanent hea... | wikipedia |
8d7086d3d6c8d2b79adc3281f9b44d08aa522e4f | igoris pankratjevas (born 9 august 1964) is a | igoris pankratjevas (born 9 august 1964) is a lithuanian professional football coach and a former player. he made his debut in the soviet top league in 1983 for fk Žalgiris vilnius. | wikipedia |
080f164b7b6dde127c9c47d9097088307e90627b | human systems integration (hsi) is an interdisciplinary managerial | human systems integration (hsi) is an interdisciplinary managerial and technical approach to developing and sustaining systems which focuses on the interfaces between humans and modern technical systems. the objective of hsi is to provide equal weight to human, hardware, and software elements of system design throughou... | wikipedia |
f0481c9332d375db50dbf0dc3cab574bb63c0ce7 | habitability is the application of human centered design | habitability is the application of human centered design to the physical environment (living areas, personal hygiene facilities, working areas, living areas, and personnel support areas) to sustain and optimize morale, safety, health, comfort and quality of life of personnel. design aspects such as lighting; space; ven... | wikipedia |
7ee76b172b70e41ca97c194ca6519af16dc63b58 | survivability is design features that reduce the risk | survivability is design features that reduce the risk of fratricide, detection and probability of an attack, and enable the crew to continue the mission and avoid acute or chronic illness, severe injury, disability or death in hostile environments. elements of survivability include reducing susceptibility to a mishap o... | wikipedia |
aec0d3e8ae00c6249c7d5f7c3c37bac53cddfe9e | systems safety is grounded in a risk management | systems safety is grounded in a risk management process but safety risk management has a unique set of processes and procedures. for example, identified hazards should be designed out of the system whenever possible, either through selecting a different design, or altering the design to eliminate the hazard. if a desig... | wikipedia |
0853dc777333ac084ab8568aa72a0dd19e465d84 | a health hazard analysis should be performed periodically | a health hazard analysis should be performed periodically during the system lifecycle to identify risks, initiating the risk management process. in dod programs, program managers must prepare a programmatic environmental, safety and occupational health evaluation (peshe) which is an overall evaluation of esoh risks for... | wikipedia |
ff1282b06d71174fdda1bd3560a218ab7e3a0b95 | the environment, safety and occupational health domain is | the environment, safety and occupational health domain is focused on determining system design characteristics that minimize risks to human health and physical wellbeing such as acute or chronic illness, disability death, or injury. in a physical system design, systems safety works closely with systems engineers to ide... | wikipedia |
3bf00abef5a0a65d44f167416c860bbe1e06ba9a | the training domain is concerned with giving the | the training domain is concerned with giving the target audience the opportunity to acquire, gain or enhance the knowledge, skills and abilities needed to operate, maintain and support a system. the target audience may be individuals or groups; training in a systems engineering / acquisition setting is focused on job-r... | wikipedia |
f53de0e91974abf008480a8278eae8eca948542b | the personnel domain is concerned with the human | the personnel domain is concerned with the human performance characteristics of the user population (cognitive, sensory and physical skills, knowledge, experience and abilities) of operators, maintainers and support staff required for a system. cost effective engineering designs minimize personnel requirements, and kee... | wikipedia |
d61425125ac44ef125713c4413137ed4dd27dcca | manpower focuses on evaluating and defining the right | manpower focuses on evaluating and defining the right mix of personnel (sometimes referred to as "spaces") for people to operate, maintain and support a system. manpower requirements should be based on task analysis and consider workload, fatigue, physical and sensory overload, environmental conditions (heat/cold) and ... | wikipedia |
5c0a1376465f78b9120191a108fb8dd14fb293de | human factors engineering (hfe) is an engineering discipline | human factors engineering (hfe) is an engineering discipline that ensures human capabilities and limitations in areas such as perception, cognition, sensory and physical attributes are incorporated into requirements and design. effective hfe ensures that systems design capitalizes on, and does not exceed, the abilities... | wikipedia |
fea4fac313e1f92ee2a073d74e280b8914bd171c | design interface (including hsi) is the integration of | design interface (including hsi) is the integration of quantitative systems design characteristics with functional integrated product support elements. in this element of logistics, the systems design parameters drive product support resource requirements. product support requirements are derived to ensure the system m... | wikipedia |
95d1cd40c00188c9d44f273a6716159fd49c67a3 | planning and management for cost and performance across | planning and management for cost and performance across the lifecycle of a system are accomplished through lifecycle logistics and integrated product support. these activities ensure that the system will meet sustainment objectives and satisfy user sustainment objectives. product support management covers three focus a... | wikipedia |
e92328d73ba086e68ad508691dac1f84bcc361ef | the incose systems engineering handbook provides an authoritative | the incose systems engineering handbook provides an authoritative reference to understand the discipline of systems engineering for student and practicing professionals. the human part of the system is associated with systems engineering activities from start to finish: from requirements development, to architectural d... | wikipedia |
703f9559f511cc63c9fae91cc90a7b1ffbec4629 | the standard practice for human systems integration (sae | the standard practice for human systems integration (sae 6906) was issued in 2019, and defines standard practices for procurement activities related to hsi. the standard is provided for industry to apply hsi during system design, through disposal and all related activities. this standard includes an overview of hsi and... | wikipedia |
c6ee39ca818564615f2aaec3dfe168b7067b92a4 | the defense acquisition guidebook, first published in 2002, | the defense acquisition guidebook, first published in 2002, devotes an entire chapter to manpower planning and hsi. in addition to focused discussion on each domain, the dag emphasizes viewing hsi from a total system perspective, viewing the human components of a system as integral to the total system as any other comp... | wikipedia |
f1f2e98046664b28c68e2eddc343b13cf34ba80a | dod acquisition policy to formalize manpower, personnel, training | dod acquisition policy to formalize manpower, personnel, training and safety processes started in 1988. hsi as a distinct focus area was first addressed in the operation of the defense acquisition system (dodinst 5000.02) issued in 2003. updated in 2008, this policy expanded the six domains in the manprint program to s... | wikipedia |
5036b5e914f4d96480e0c52dbafa5a2078508dd3 | the us navy initiated the military manpower versus | the us navy initiated the military manpower versus hardware (hardman) methodology in 1977 to address problems with manpower, personnel and training in the service. in 1980, the national academies of sciences, engineering, and medicine established the committee on human factors, which was later renamed the committee on ... | wikipedia |
ac5abedc83157c4a74738c38de9d939e1cef5829 | the us navy initiated the military manpower versus | the national transportation safety board) and nasa ames research center also address hsi. the united kingdom, canada, australia and new zealand have hsi programs similarly rooted in human factors and modeled after the army manprint program. in europe hsi is known as human factors integration. | wikipedia |
1c11afa5593fa1ec7d5df560b7f0f00ea0360e1f | hsi is a total systems approach that focuses | hsi is a total systems approach that focuses on the comprehensive integration across the hsi domains, and across systems engineering and logistics support processes. the domains of hsi are interrelated: a focus on integration allows tradeoffs between domains, resulting in improved manpower utilization, reduced training... | wikipedia |
132413a1cc23b4f38e944a98a5068f2596ba8008 | human systems integration (hsi) is an interdisciplinary managerial | human systems integration (hsi) is an interdisciplinary managerial and technical approach to developing and sustaining systems which focuses on the interfaces between humans and modern technical systems. the objective of hsi is to provide equal weight to human, hardware, and software elements of system design throughou... | wikipedia |
d99e26fb207b0cbd02987194cd653e617110717b | janne jokila is a finnish former professional ice | janne jokila is a finnish former professional ice hockey player who last played for milton keynes lightning in the english premier ice hockey league. his former teams include hc tps of the sm-liiga and syracuse crunch of the ahl. his career began with hc tps before moving to north america in 2002 after taking part in t... | wikipedia |
6c3e0587390f81b386e16fce87722a3cfa725a9f | his career began with hc tps before moving | his career began with hc tps before moving to north america in 2002 after taking part in the 2000 nhl entry draft, being selected by the columbus blue jackets, although he would never go on to play in the nhl. he returned to finland in 2005 and moved to the uk in 2012. | wikipedia |
6c605ceb1ac2b0c5a557e137df9137f02fd28b47 | janne jokila (born april 22, 1982) is a | janne jokila (born april 22, 1982) is a finnish former professional ice hockey player who last played for milton keynes lightning in the english premier ice hockey league. his former teams include hc tps of the sm-liiga and syracuse crunch of the ahl. | wikipedia |
9b0bd0d4cde2053cd36a14ebc3bc0ff9f30a8feb | james pollard espy was a u.s. meteorologist. espy | james pollard espy was a u.s. meteorologist. espy developed a convection theory of storms, explaining it in 1836 before the american philosophical society and in 1840 before the french académie des sciences and the british royal society. his theory was published in 1840 as the philosophy of storms. he became meteorolog... | wikipedia |
ed6148d4477cd84e6b70beb1418d17ea146b5b60 | his work in washington, d. c. was concluded | his work in washington, d. c. was concluded in 1859 and he then spent some time in visiting his relatives and friends in ohio and pennsylvania. while on a visit to cincinnati, ohio, professor espy was stricken with paralysis january 17, 1860 and died at the residence of his nephew, john westcott, january 24. he was bur... | wikipedia |
403e5d9bedde50fd10fbaba3a2e9c5718a015c68 | in 1843 he was appointed the first meteorologist | in 1843 he was appointed the first meteorologist of the u.s. government and was assigned to duty, first under the surgeon general of the army, next under the secretary of the navy and finally in 1848 under the secretary of the smithsonian institution. | wikipedia |
6678ffa19349f7e5dac14158f2f92afb102d2eec | in 1836 he abandoned the profession of teaching | in 1836 he abandoned the profession of teaching and began lecturing before scientific bodies and popular audiences. these lectures caused him to be popularly known as the storm king. in 1840 he visited europe and presented his theory of storms before the british science association and the french academy of science. it... | wikipedia |
806d6ea8b9154361aacbd00b32e49612e87ca114 | in 1834 espy became meteorologist for both the | in 1834 espy became meteorologist for both the franklin institute and the american philosophical society (aps) of philadelphia. as chair of a joint committee, he established a network of weather observers to study storms. he convinced the pennsylvania legislature to appropriate $4,000 to equip an observer in each count... | wikipedia |
3e16b5b0bd2f564ceefbac5a48e94c60ab52d37f | espy had an ardent desire for knowledge and | espy had an ardent desire for knowledge and commenced teaching school as a means to obtaining a classical education at transylvania university, lexington, kentucky. after leaving the university in 1808 he taught an academy at cumberland, maryland. he studied law and practiced that profession four years at xenia, ohio. ... | wikipedia |
a8fbe4d5b282da82e772cfe9a2944f248f48978d | james pollard espy (or the storm king) (may | james pollard espy (or the storm king) (may 9, 1785 – january 24, 1860) was a u.s. meteorologist. espy developed a convection theory of storms, explaining it in 1836 before the american philosophical society and in 1840 before the french académie des sciences and the british royal society. his theory was published in 1... | wikipedia |
fa3ec6169ad26a319a5c61c679d388a0077553bc | hyman worked at the vineland training school (then | hyman worked at the vineland training school (then known as the american institute for mental studies) as chief of clinical services from 1966 to 1967. he then briefly taught at newark state college before joining the faculty of temple university in 1968. he was initially an associate professor of school psychology at ... | wikipedia |
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