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9203cf919aef2c2ac9c3b7cdcdf87b9465c42d6c
thus by using the riemann–silberstein vector, it is
thus by using the riemann–silberstein vector, it is possible to reexpress the maxwell's equations for a medium with constant ε = ε (r, t) {\displaystyle \varepsilon =\varepsilon (\mathbf {r},t)} and μ = μ (r, t) {\displaystyle \mu =\mu (\mathbf {r},t)} as a pair of constitutive equations.
wikipedia
4aabb509c9510c410f8814b325d95417bb45efff
if for a certain medium ε = ε
if for a certain medium ε = ε (r, t) {\displaystyle \varepsilon =\varepsilon (\mathbf {r},t)} and μ = μ (r, t) {\displaystyle \mu =\mu (\mathbf {r},t)} are scalar constants (or can be treated as local scalar constants under certain approximations), then the vectors f ± (r, t) {\displaystyle {\mathbf {f} }^{\pm }(\mathb...
wikipedia
7177922523d0f86faad07ad004fd6702e37854de
in vacuum, ε 0 = {\displaystyle \varepsilon _{0}=\,}
in vacuum, ε 0 = {\displaystyle \varepsilon _{0}=\,} 8.85 × 10 c ·n ·m and μ 0 = 4 π {\displaystyle \mu _{0}=4\pi \,} × 10 h·m
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96f7c2c8c8deae948533a4dd87beff0d717f110e
where scalar ε = ε (r, t) {\displaystyle
where scalar ε = ε (r, t) {\displaystyle \varepsilon =\varepsilon (\mathbf {r},t)} is the permittivity of the medium and scalar μ = μ (r, t) {\displaystyle \mu =\mu (\mathbf {r},t)} the permeability of the medium (see constitutive equation). for a homogeneous medium ε {\displaystyle \varepsilon } and μ {\displaystyle \...
wikipedia
ba2bff43f7adde5e6212d3583918b52d05f641df
in electromagnetism, a branch of fundamental physics, the
in electromagnetism, a branch of fundamental physics, the matrix representations of the maxwell's equations are a formulation of maxwell's equations using matrices, complex numbers, and vector calculus. these representations are for a homogeneous medium, an approximation in an inhomogeneous medium. a matrix representat...
wikipedia
5430e39b7e5ac682bbc42c11c7305f859c41f776
jiaodong kingdom was a kingdom of the han
jiaodong kingdom was a kingdom of the han dynasty, located in what is now eastern shandong. zichuan was separated from the qi kingdom in 165 bc and granted to liu xiongqu (劉熊渠), son of liu fei, king of qi. xiongqu was killed in the rebellion of the seven states, and was succeeded by liu che, son of emperor jing, and th...
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caebb58db8980bdd798aedbff711691d81c04472
liu yin (劉殷), 14 bc – 8 ad.
liu yin (劉殷), 14 bc – 8 ad. the last king of jiaodong was deposed after the usurpation of wang mang. after the restoration of eastern han, jiaodong was merged into beihai commandery. in late western han, jiaodong consisted of 8 counties, namely jimo (即墨), changwu (昌武), xiami (下密), zhuangwu (壯武), yuzhi (郁秩), ting (挺), g...
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dc829e3dae4c9ce0604f2f8db9c04497ebed8e11
in late western han, jiaodong consisted of 8
in late western han, jiaodong consisted of 8 counties, namely jimo (即墨), changwu (昌武), xiami (下密), zhuangwu (壯武), yuzhi (郁秩), ting (挺), guanyang (觀陽) and zoulu (鄒盧). the population in 2 ad was 323,331, or 72,002 households.
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d52066b240c103b8fabae75af8b8f02403b5bdef
zichuan was separated from the qi kingdom in
zichuan was separated from the qi kingdom in 165 bc and granted to liu xiongqu (劉熊渠), son of liu fei, king of qi. xiongqu was killed in the rebellion of the seven states, and was succeeded by liu che, son of emperor jing, and the future emperor wu. after che was designated as the heir to the han throne, jiaodong was co...
wikipedia
dadbb54712f2896400d56a9e02e52a73bb0ad9c0
kronenberg was elected a fellow of the american
kronenberg was elected a fellow of the american association for the advancement of science in 2015. he received the distinguished service award from the american association of immunologists (aai) and was elected a distinguished fellow of the aai in 2019.
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e264aa1f187603f4b229b0b7085d2609f6b54f51
kronenberg's work had a major impact in defining
kronenberg's work had a major impact in defining how glycolipid antigens are taken into cells and processed in lysosomes and unraveled the intracellular traffic of cd1d, which is the mhc class i molecule that presents lipid antigens. he has led the field in defining microbial antigens from environmental bacteria and fr...
wikipedia
64b88923910835b2ebc1ff0fc3f0347f28b86181
the kronenberg lab focuses on understanding innate-like lymphocytes,
the kronenberg lab focuses on understanding innate-like lymphocytes, mainly natural killer t (nkt) cells, a subset of t cells that recognizes glycolipids and is involved in a variety of immune responses including autoimmune, anti-tumoral responses and antimicrobial responses. kronenberg also has research in mucosal imm...
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67b2d6bd44380611461c7d9f2a9ce09b1e5be8fa
kronenberg is an adjunct professor of biology at
kronenberg is an adjunct professor of biology at uc san diego and co-directs the program in immunology, a collaborative effort between la jolla institute and uc san diego. during his leadership, lji formalized its ties with uc san diego, maintained its relationship with kyowa kirin, expanded its core facilities and tec...
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60c246038350d1094a872c0ce39205ba72199ab1
in 1986, kronenberg joined the faculty at ucla,
in 1986, kronenberg joined the faculty at ucla, where he rose through the ranks and was promoted to full professor in 1997. in 1997, he moved to la jolla institute for immunology (lji) to head the division of developmental immunology. he was appointed president and chief scientific officer of lji in 2003.
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c6555b3c5af8155a3db9b6a7ded32aa633a7a1dc
mitchell kronenberg (born december 12, 1951) is an
mitchell kronenberg (born december 12, 1951) is an american immunologist and the chief scientific officer at la jolla institute for immunology. he served as president of the institute from 2003 to 2021.
wikipedia
b82543833d5fd787a997a343acbad918a74f05b7
miyamura station (宮村駅, miyamura-eki) is a passenger railway
miyamura station (宮村駅, miyamura-eki) is a passenger railway station in located in the city of miyazu, kyoto prefecture, japan, operated by the private railway company willer trains (kyoto tango railway).
wikipedia
ecee7eecc7a5025c32ae4d3d0a96596eea9abc6d
hirohata station (広畑駅, hirohata-eki) is a passenger railway
hirohata station (広畑駅, hirohata-eki) is a passenger railway station located in the city of himeji, hyōgo prefecture, japan, operated by the private sanyo electric railway.
wikipedia
8a51fbff321929215b9acc5146618022522df960
after three seasons with klagenfurt, lammers opted to
after three seasons with klagenfurt, lammers opted to join rivals ec vsv on a one-year contract as a free agent on april 8, 2014. in the 2014–15 season with vsv, lammers contributed with 13 goals and 36 points in 54 games.
wikipedia
e128854587c2eb2f31e0dd8856933f9a0bdf1bb0
john lammers (born january 29, 1986) is a
john lammers (born january 29, 1986) is a canadian professional ice hockey forward who currently plays for esv kaufbeuren in the del2. he was selected by the dallas stars in the 3rd round (86th overall) of the 2004 nhl entry draft.
wikipedia
52a1f0cf789b3997a3cb50658622c12d6312cfc0
ishinomaki station opened on october 28, 1912 on
ishinomaki station opened on october 28, 1912 on what would become the ishinomaki line. on november 22, 1928, miyaden-ishinomaki station (宮電石巻駅) opened, served by the miyagi electric railway (the present-day senseki line). on may 1, 1944, the miyagi electric railway was nationalized and miyaden-ishinomaki station was r...
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9efd362b695747094f92a33c73ada17628dca04a
the station has one bay platform for the
the station has one bay platform for the senseki line with two bays, and a side platform and an island platform for the ishinomaki line. the platforms are connected by a footbridge. the station has a " midori no madoguchi " staffed ticket office.
wikipedia
f568dbed862f5e589a910a83a88cca7f265186b6
ishinomaki station is served by both the ishinomaki
ishinomaki station is served by both the ishinomaki line and the senseki line / senseki-tōhoku line, for which it is a terminal station. it is located 27.9 kilometers from the terminus of the ishinomaki line at kogota station and 49.0 kilometers from the opposing terminus of the senseki line at aoba-dōri station, and 4...
wikipedia
b2be1757d05c7334e364a0849165b94270acadd1
ishinomaki station (石巻駅, ishinomaki-eki) is a junction railway
ishinomaki station (石巻駅, ishinomaki-eki) is a junction railway station located in the city of ishinomaki, miyagi, japan, operated by east japan railway company (jr east).
wikipedia
78b676b2a55dc61d03a9a8ff782caa76bad0dbd3
jan rath is a dutch social scientist who
jan rath is a dutch social scientist who is holding a chair in urban sociology in the university of amsterdam, the netherlands. his academic studies have focused on the nexus of urban structures and processes on the one hand and their social, ethnic and religious dimensions on the other. his work is highly cited in the...
wikipedia
6588e1f2a1815b2a3f3b30f0cf3f5fa5f8f54698
in a later phase, rath together with the
in a later phase, rath together with the economic geographer robert kloosterman and colleagues, he developed the mixed embeddedness approach to the study of small (ethnic) entrepreneurship. the ‘mixed embeddedness’ approach is an attempt to develop a theory that combines agency factors with structural conditions in a m...
wikipedia
0b7b58582a0ad266575cd5443700032fddf26513
in the early phases of his career, rath
in the early phases of his career, rath positioned himself in the international debate on racism and discrimination. at the time, many students of racism put the colonial model central in their considerations and assumed that the only or the most important racism is that which has black people as its object. rath, howe...
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e5f3ac269ffd60f5a6de45c6dd13dce1459a5d93
in the early phases of his career, rath
represented as races apart but as minorities apart. the crux is that in the dutch case these socio-cultural features are not regarded as fixed or naturalized. as a matter of fact, the state and private institutions had done their utmost to integrate and assimilate these people, in other words, to change them.
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f137c42381fed38cbda89819447fa70c38b8c458
moreover, he has been the chair of metropolis
moreover, he has been the chair of metropolis international, a member of the imiscoe research network, an associate of the world economic forum, and a member of the advisory board of the centre on migration, policy, and society (compas) within the university of oxford. he has been an advisor of a wide array of local, n...
wikipedia
77cd59b6db7b17fcc1da974263392e4447524e39
in between, he was a visiting scholar at
in between, he was a visiting scholar at the university of california los angeles (ucla), massey university in auckland, new zealand, and koç university and nit in istanbul. moreover, during his fellowship at the netherlands institute of advanced study (nias-knaw), he was appointed as the holder of the prof. dr. j.a.a....
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3e1510c5e54d284fc6e9af663bd00d343bf44bfc
he held academic posts at the center for
he held academic posts at the center for the study of social conflicts (comt) in leiden university (1982-1986), the center for the study of multi-ethnic society (smes) in utrecht university (1986-1990), the institute for the sociology of law in the catholic university of nijmegen (currently named radboud university), (...
wikipedia
a3e5e0fbaf795b5fa8c9bf846eeb90867ffaeda4
after attending secondary school, rath spent two years
after attending secondary school, rath spent two years doing all sorts of jobs (packing tomatoes, moving furniture, x-raying industrial installations, and counting bus passengers) and traveling. thereafter, he decided to enroll in the anthropology and urban studies programs at utrecht university. he received his ma deg...
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41ff553fe5df1fa954a31098fbaeb118bbd9550c
jan rath was born in the city of
jan rath was born in the city of rotterdam, the netherlands, and grew up in a lower-class family in afrikaanderwijk and hillesluis, both poor blue-color neighborhoods located close to the ports in the southern part of the city.
wikipedia
78b676b2a55dc61d03a9a8ff782caa76bad0dbd3
jan rath is a dutch social scientist who
jan rath is a dutch social scientist who is holding a chair in urban sociology in the university of amsterdam, the netherlands. his academic studies have focused on the nexus of urban structures and processes on the one hand and their social, ethnic and religious dimensions on the other. his work is highly cited in the...
wikipedia
6d3da241af3f1ac8bc5a955d1d736e37b2516dc2
the station was opened on november 3, 1925
the station was opened on november 3, 1925 as kuchiōno station (口大野駅, kuchiōno-eki). on may 24, 1963 it was renamed tango-Ōmiya station (丹後大宮駅, tango-Ōmiya-eki), and renamed again to its present name on march 31, 2015.
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ff11b9b8ece7d39988d013d929ab85ced3172e82
kyōtango-Ōmiya station (京丹後大宮駅, kyōtango-Ōmiya-eki) is a passenger railway
kyōtango-Ōmiya station (京丹後大宮駅, kyōtango-Ōmiya-eki) is a passenger railway station in located in the city of kyōtango, kyoto prefecture, japan, operated by the private railway company willer trains (kyoto tango railway).
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2caa7263adabbca84f8c74615c5d7d91264dbf30
following his release from newcastle united grieve signed
following his release from newcastle united grieve signed for hometown club ashington, signed for darlington 1883, and then returned to ashington. he then moved to celtic nation f.c in september 2013 and later played for whickham in the ebac northern league 1st division.
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e65717e6561ae59fe2d727d320fe70e87efe9645
on 7 january 2011 he joined stockport county
on 7 january 2011 he joined stockport county on loan for a month, and was given the number 26 shirt. he made his football league debut the following day in a 5–1 home defeat to gillingham. three days later, in his second match for the club, he scored an own goal in a match against rotherham united. he returned to his p...
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4c1e4bd36cee66b264e7b6d797bbd310b7b45649
he joined the newcastle united academy in july
he joined the newcastle united academy in july 2007, having completing his education and having already played for the club at all levels between under 14 and under 18. he played for the under 18 team at the age of 15, and was named in the reserves at the end of the 2006–07 season. he made his reserve team debut agains...
wikipedia
db485d3f17b5a52de889ffe43400d2ffb78ff80f
this article lists various water polo records and
this article lists various water polo records and statistics in relation to the japan men's national water polo team at the summer olympics. the japan men's national water polo team has participated in 9 of 27 official men's water polo tournaments.
wikipedia
9ea39c3a88c38a2d3b2852c03d21e6aec38836ea
the following table is pre-sorted by number of
the following table is pre-sorted by number of total sprints won (in descending order), year of the last olympic appearance (in ascending order), year of the first olympic appearance (in ascending order), name of the sprinter (in ascending order), respectively.
wikipedia
2fcdaaea367ac05e845c0f8532b7081fa4f03c02
the following table is pre-sorted by number of
the following table is pre-sorted by number of total goals (in descending order), year of the last olympic appearance (in ascending order), year of the first olympic appearance (in ascending order), name of the player (in ascending order), respectively.
wikipedia
bcf6c9e4203468e8d35c53406f612afc57416ff9
the following table is pre-sorted by number of
the following table is pre-sorted by number of olympic appearances (in descending order), year of the last olympic appearance (in ascending order), year of the first olympic appearance (in ascending order), date of birth (in ascending order), name of the player (in ascending order), respectively.
wikipedia
80465efe953da15bd1c6b75bb14d41cdc94ad5bf
kp1019, or indazole trans-[tetrachlorobis(1h-indazole)ruthenate(iii)], is one of four
kp1019, or indazole trans-[tetrachlorobis(1h-indazole)ruthenate(iii)], is one of four ruthenium anti-cancer drugs to enter into phase i clinical trials, the others being bold-100, nami-a and tld-1433. research into ruthenium-based drugs has provided novel alternatives for platinum-based chemotherapeutics such as cispla...
wikipedia
0c2375b4e96069bfefe59ccc7a5eef50c4798ed9
kp1019 was administered to patients twice weekly in
kp1019 was administered to patients twice weekly in doses ranging from 25 mg to 600 mg for three weeks. patients had advanced solid tumors. five out of six patients saw disease stabilization for up to 10 weeks. no serious side effects of kp1019 were reported.
wikipedia
6165830307ca87e7d1dcabcce8fae6e8096fa6ea
kp1019 and kp1339 both induce apoptosis in colorectal
kp1019 and kp1339 both induce apoptosis in colorectal tumor cell lines sw480 and ht29. this is induced predominantly by a loss of mitochondrial membrane potential in a high percentage of cells. dna strand breaks are not believed to be the cause of the major damage. this is due to kp1019-induced death being independent ...
wikipedia
4b724e2ed5451913d5e0a1bf1ce073f2cb40bddf
most metal-based anti-tumor compounds interact strongly with dna.
most metal-based anti-tumor compounds interact strongly with dna. binding assays of kp1019 with the four common nucleotide bases reveal a preference for guanosine 5’-monophosphate and adenosine 5’-monophosphate. kp1019 is able to untwist and bend dna weakly. while pt-based compounds also target purines, kp1019's dna le...
wikipedia
94c8b4ab23d480a1acb858753edd34098c127171
human serum albumin, the most present protein in
human serum albumin, the most present protein in blood plasma, binds to kp1019 in a 1:4 protein:drug ratio. in plasma, it is almost exclusively bound to protein, up to 90%. it is possible that albumin serves to bind available ru drugs until they are transported into the cell by tf.
wikipedia
29c312c9b6ac17b03ec288e7473be0dca53c8317
kp1019 binds transferrin (tf), a 700 amino acid
kp1019 binds transferrin (tf), a 700 amino acid glycoprotein, in the pocket usually bound to 2 atoms of fe. the transferrin protein binds to the transferrin receptor and is taken into the cell by endocytosis. this protein and its receptors are overexpressed in cancer cells owing to their increased demand for iron, and ...
wikipedia
11db236f85a5f74a16c9fe657e0dd1c8aaeaae6c
the active form of kp1019 has ru in
the active form of kp1019 has ru in its 2+ state. the hypoxic environment of cancer cell tissue facilitates this reduction and the specific action on cancer cells over healthy cells. the intracellular reducing agent is unknown, but glutathione is a good candidate as it reduces promiscuously and has a reduction potentia...
wikipedia
8ed15059796a46f2ef9a89cc3af9a25bdb5640c5
kp1019 is synthesized by refluxing rucl -3h o
kp1019 is synthesized by refluxing rucl -3h o with hcl and ethanol. the ethanol is removed and indazole is allowed to react with the solution at 70 °c. the resulting solid is collected by filtration and its purity is evaluate by uv-visible spectroscopy, elemental analysis, and determination of reduction potential.
wikipedia
2d9ba59360a63e5db87d2f6c7328af00328b6227
due to its low solubility in water, kp1019
due to its low solubility in water, kp1019 is often prepared as its sodium salt, the basis for kp-1339 and bold-100. by replacing the indazole rings with imidazole rings the derivative kp418 is formed. kp418 also exhibits anti-cancer activity, however it has not completed phase i clinical testing. kp418 exhibits slower...
wikipedia
d0694114b718953aa9af67d49d38fd62c1036b57
kp1019 has an octahedral structure with two trans
kp1019 has an octahedral structure with two trans n-donor indazole and four chloride ligands in the equatorial plane. it has a low solubility in water, which makes it difficult to transport in the bloodstream. the ru-cl bonds are labile and kp1019 readily exchanges its chloro ligands in the presence of water.
wikipedia
15c596ef71ae68f570b47ea27eac9a759baa69c5
kp1019, or indazole trans -, is one of
kp1019, or indazole trans -, is one of four ruthenium anti-cancer drugs to enter into phase i clinical trials, the others being bold-100, nami-a and tld-1433. research into ruthenium-based drugs has provided novel alternatives for platinum-based chemotherapeutics such as cisplatin and its derivatives. kp1019 is useful ...
wikipedia
e47b87ed622f721f5307f99f8ce15e2ec8788295
hugh victor perkins jr. was an american educator,
hugh victor perkins jr. was an american educator, author, and emeritus professor of education at the department of human development, university of maryland - college park. he has been recognized as one of the most important educational thinkers in history. his influence on developmental psychology, teaching, learning,...
wikipedia
3d7acd1983ff40cad0909113b837053a4f1e0d79
in 1958–1959, perkins received a fulbright fellowship to
in 1958–1959, perkins received a fulbright fellowship to give workshops and lectures all over pakistan. his child development course in karachi is considered the first of its kind for educators and parents in pakistan. perkins served as deputy director of the institute for child study in the college of education at the...
wikipedia
0336ae0cd245f9698485a8eb7bc56e0cabc34775
perkins was born in toledo, ohio, and raised
perkins was born in toledo, ohio, and raised in cleveland heights, ohio. his mother was frances adams perkins and his father, hugh v. perkins sr., was a vice principal at cleveland heights high school and received his ph.d. in education from western reserve university. hugh v. jr. ("vic") graduated oberlin college with...
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2775c771e1a133446c013b6742362fb050d82142
hugh victor perkins jr. (june 9, 1918 –
hugh victor perkins jr. (june 9, 1918 – february 10, 1988) was an american educator, author, and emeritus professor of education at the department of human development, university of maryland - college park. he has been recognized as one of the most important educational thinkers in history. his influence on developmen...
wikipedia
4c66c03b696289db6beb3ba02e58dacf711fdd02
it++ is a c++ library of classes and
it++ is a c++ library of classes and functions for linear algebra, numerical optimization, signal processing, communications, and statistics. it is being developed by researchers in these areas and is widely used by researchers, both in the communications industry and universities. the it++ library originates from the ...
wikipedia
80adeba27845858db298d49acef212b194ecdb47
acml - includes blas, lapack and fft routines.
acml - includes blas, lapack and fft routines. it is possible to compile and use it++ without any of the above-listed libraries, but the functionality will be reduced. it++ works on linux, solaris, windows and os x operating systems.
wikipedia
555ab13e9409508c9df8b29e164d277b430d7de6
it is possible to compile and use it++
it is possible to compile and use it++ without any of the above-listed libraries, but the functionality will be reduced. it++ works on linux, solaris, windows (with cygwin, mingw/msys, or microsoft visual c++) and os x operating systems.
wikipedia
ae72a4f11c8fd9174c35d8391897beb818591970
the kernel of the it++ library is templated
the kernel of the it++ library is templated vector and matrix classes, and a set of accompanying functions. such a kernel makes it++ library similar to matlab / octave. for increased functionality, speed and accuracy, it++ can make extensive use of existing free and open source libraries, especially blas, lapack and ff...
wikipedia
68d105352990abd146f812999f6a16a299015590
it++ is a c++ library of classes and
it++ is a c++ library of classes and functions for linear algebra, numerical optimization, signal processing, communications, and statistics. it is being developed by researchers in these areas and is widely used by researchers, both in the communications industry and universities. the it++ library originates from the ...
wikipedia
7ac9f5981b7b037a120995523012235e44033d97
an i-1 visa is a non-immigrant visa issued
an i-1 visa is a non-immigrant visa issued by the united states for foreign media representatives and journalists who travel to the united states for the purpose of working exclusively in their profession. all applicants must meet eligibility criteria, which requires them to be residents of foreign countries, working f...
wikipedia
9432b4cca05b587c5b621ee0cee6551ee253325e
the number of i visas issued varies from
the number of i visas issued varies from year to year: 13,674 were granted in fy 2014; 14,447 in fy 2015; 14,536 in fy 2016; 14,126 in fy 2017; and 11,874 in fy 2018. in 2018, the nations with the largest number of i visa recipients were the united kingdom (1,768 visas granted); japan (1,205); germany (888); mexico (70...
wikipedia
c8617c80211b735d8b61abe4c2fe5d2d018d26ba
change of the i visa holder's status from
change of the i visa holder's status from one nonimmigrant category to another is conducted through filing an application to extend/change nonimmigrant status (form i-539). an applicant must gather necessary documentation, undergo the prescribed procedure and pay necessary fees, as well as to provide evidence of their ...
wikipedia
aeaf495c07eb628b8dd6068b4d89aef76fc552cc
the i visa holder has a right to
the i visa holder has a right to extend their stay in the united states for an unlimited amount of time by filing an application to extend/change nonimmigrant status (form i-539) and providing the necessary documentation and fees. the procedure of extension does not require the holder of a media visa to leave the count...
wikipedia
861500c898139606cca487b4341c83455c55bda8
the i visa is usually issued for one
the i visa is usually issued for one year. upon arrival to the us port-of-entry, every i visa holder is provided with form i-94 and a stamp that determines a time frame of their authorized stay in the country. i visa holders are not required to leave or re-enter the country during their stay, but must leave the united ...
wikipedia
c27209d626b1012f9272b001f331cef4312377b1
spouses and children of the i visa holder
spouses and children of the i visa holder can legally travel to the united states with them after obtaining the same type of visa (derivative visa). immediate family members are allowed to study, but they are not allowed to take any job while staying in the united states.
wikipedia
44021477220365400db3b05438b6ba4761b0aa4b
every foreign media representative who is willing to
every foreign media representative who is willing to visit the united states to engage in the media profession must apply for the i visa. american immigration law does not allow holders of other visa types or those visiting the united states under any other status or programs, such as the visa waiver program., to work ...
wikipedia
ac0cfc52696269660e50102b9b4edd69c919483f
applicants for the i-1 visa must be able
applicants for the i-1 visa must be able to prove that their activities in the united states are of great value to the employing organization. these activities must not have any commercial motive, such as entertainment or advertising, while the organization itself must represent press, radio, film, print or other types...
wikipedia
12fef7510d7c1acba2c524bdab7f586a0c1de114
the i-1 visa does not grant anyone guaranteed
the i-1 visa does not grant anyone guaranteed entry to the united states. it initially gives the holder permission to travel to the united states port-of-entry for an interview with a representative of the united states citizenship and immigration services, who decides whether or not the holder should be given the righ...
wikipedia
0c56bd04826f9d73c19d442a5807298cd7561d88
an i-1 visa is a non-immigrant visa issued
an i-1 visa is a non-immigrant visa issued by the united states for foreign media representatives and journalists who travel to the united states for the purpose of working exclusively in their profession. all applicants must meet eligibility criteria, which requires them to be residents of foreign countries, working f...
wikipedia
788ac514c281185bee67cb32aac0244fa0f222b9
the moray bridge, also known as the moray
the moray bridge, also known as the moray channel bridge, and formerly the middle arm bridge, is a crossing over the middle arm of the fraser river in metro vancouver. richard moody, who would name geographical features, such as this channel, after acquaintances, honoured jonathan moray (1824–84), a sergeant in the cor...
wikipedia
4139d7c9b516a534b447b75a920d5500e14eec57
the single lane each way, 1957–2001, was subject
the single lane each way, 1957–2001, was subject to traffic congestion from vehicle accidents, swing span openings for boats, or rush hour volumes. linking sea island way on lulu island and miller rd on sea island, the roadway intersected airport rd. on construction in the late 1970s, russ baker way became the new inte...
wikipedia
a87387d921b6864f093c22462bab95c55964a0bd
prior to the 1969 opening of the dinsmore
prior to the 1969 opening of the dinsmore bridge, the moray bridge was the only crossing in existence.consequently, when the span malfunctioned, as it did twice in 1961, traffic could be trapped for several hours. the non-arrival of passengers and crew delayed some airport flights. mechanical and electrical issues cont...
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c9d5b9a0d27bb0b4ceda441fa63e7ab25c7f8133
within a few years of construction, scouring required
within a few years of construction, scouring required repairing and surrounding the protection piers with rock. the expansion joints were repaired in 1962–63. attached to the western approach, the tender house was replaced the following year. this small building houses the human operator of the swing-span controls. in ...
wikipedia
4d58df1d368663e128efa5380f0b3d47ee38eadd
the concrete and steel second bridge across the
the concrete and steel second bridge across the moray channel cost about $1m, of which the federal government contributed $400,000. the ministry of transportation and infrastructure for bc owns and maintains this low-level two-lane bridge. the centre swing span is 53 metres, and the approaches are 170 metres on lulu is...
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741ca0c8da7f026bc27d53ecd6a23a9eaa663cdf
opened in july 1957, the same date as
opened in july 1957, the same date as the oak street bridge, these links replaced the marpole bridge (road). the new configuration created a more circuitous route between vancouver and vancouver international airport (yvr), not restored until the arthur laing bridge opened in 1975.
wikipedia
788ac514c281185bee67cb32aac0244fa0f222b9
the moray bridge, also known as the moray
the moray bridge, also known as the moray channel bridge, and formerly the middle arm bridge, is a crossing over the middle arm of the fraser river in metro vancouver. richard moody, who would name geographical features, such as this channel, after acquaintances, honoured jonathan moray (1824–84), a sergeant in the cor...
wikipedia
3a42168cb135924b0d483555f5c1e0854ac7222c
wilkes did an undergraduate degree at the university
wilkes did an undergraduate degree at the university of sydney and a dphil at the university of oxford in 1984. she then taught at monash university in melbourne and then the university of auckland. she became a professor in 2013. she specialises in women writers whose recognition has faded.
wikipedia
6434fe557a7df8faf0f56d157c98a30bee13be6a
karl theodor menke was a german malacologist and
karl theodor menke was a german malacologist and balneologist who was a native of bremen. he is remembered for his research on snails. menke studied medicine at the university of göttingen, and worked as a physician at the spa in bad pyrmont. in 1831 he was elected a member of the academy of sciences leopoldina. in 184...
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42279c936f5796c381a0f03bc59d8d37285d4e57
the sea snail species; cerithium menkei and natica
the sea snail species; cerithium menkei and natica menkeana are named in honor of menke.also in 1843, menkea a genus of flowering plants from australia, belonging to the family brassicaceae was published and named in his honour.
wikipedia
b6b318f9713135c86912188fd77743752ae2ef7d
menke studied medicine at the university of göttingen
menke studied medicine at the university of göttingen (with promotion in 1814), and worked as a physician at the spa in bad pyrmont. in 1831 he was elected a member of the academy of sciences leopoldina. in 1844 he founded the journal zeitschrift für malakozoologie (from 1854 titled malakozoologische blätter). with lud...
wikipedia
8cb6ff8a9f4cb7d83f357827888676f52c19e16f
microbial arene oxidation (mao) refers to the process
microbial arene oxidation (mao) refers to the process by which microbial enzymes convert aromatic compounds into more oxidized products. the initial intermediates are arene oxides. a number of oxidized products are possible, the most commonly employed for organic synthesis are cis-1,2-dihydroxy-cyclohexa-3,5-dienes ("d...
wikipedia
2788281abdf2efcc880aaaed97a6391a6b0d5dd5
benzoic acid dioxygenases (bzds) the substrate specificity of
benzoic acid dioxygenases (bzds) the substrate specificity of these enzymes is low. enantiomeric purities in excess of 90% are routine but varies with substrate. for instance, 1,4-substituted benzenes often render diols of lower enantiomeric purity. however, accessing the "unnatural" enantiomer of product is often diff...
wikipedia
3f5c8d6300f1415a5766b7e5b124be55863655fe
conditions of mao reactions require handling microbes in
conditions of mao reactions require handling microbes in an aseptic environment. often, specialized bacterial strains are needed to effect particular transformations. dihydrodiols themselves must be stored under basic conditions (ph > 9) to prevent acid-catalyzed dehydration.
wikipedia
fc57f4fb447be56aba4aa24b7df4aaa13fabc652
because of concerns about the efficiency and selectivity
because of concerns about the efficiency and selectivity of oxidation of more complex substrates, mao is usually carried out early in synthetic sequences. however, simple dihydrodiols may be manipulated to give complex products through a variety of methods. in addition, the microbial oxidation process is compatible wit...
wikipedia
0e3062343cf75c752c2389492a1174e24f510096
an important limitation of the reaction is that
an important limitation of the reaction is that only a single enantiomer of product is available when the wild type enzyme is used. enzymes that generate "unnatural" enantiomers must be engineered via site-directed mutagenesis or other biochemical techniques. the development of organisms and enzymes that exhibit "unnat...
wikipedia
b5d274a7f760b39165a75868ad0f19ae91302eb3
undesirable oxidized side products are often observed during
undesirable oxidized side products are often observed during microbial arene oxidations, particularly for "unnatural" substrates. benzylic oxidation has been noted in a number of cases. sulfides are always oxidized to sulfoxides.
wikipedia
0238259deff3ac336c72d1f2f45b1fa3dd5c24e1
toluene dioxygenase oxidizes toluene to 1,2-dihydroxyl-6-methylcyclohexa-3,5-diene. aromatic esters
toluene dioxygenase oxidizes toluene to 1,2-dihydroxyl-6-methylcyclohexa-3,5-diene. aromatic esters are also good substrates for these enzymes, giving dihydrodiols in moderate yields along with some other oxidation products (see equation (8) below).
wikipedia
493afc5187360b3b8541a9793c9661a2c36f8241
a reliable model has been developed that accounts
a reliable model has been developed that accounts for the stereo- and site selectivity of the reaction. with the large substituent of the arene pointing up and other substituents pointed leftward, approach of dioxygen occurs to the top face of the arene, on the right-hand side. this model breaks down for some highly su...
wikipedia
9d42bb57b79f34b042b7559f15e121f3db7eb44f
oxidations by bacterial dioxygenases give cis -dihydrodiols. this
oxidations by bacterial dioxygenases give cis -dihydrodiols. this outcome sets the mechanism of bacterial oxidation apart from mammalian and fungal versions of the process, which yield trans -dihydrodiols. the cis configuration of the product together with isotopic labeling studies implicate a dioxetane intermediate. t...
wikipedia
5773a3b9530a792befd99701cdecdf5822e5c6a5
the substrate specificity of these enzymes is low.
the substrate specificity of these enzymes is low. enantiomeric purities in excess of 90% are routine but varies with substrate. for instance, 1,4-substituted benzenes often render diols of lower enantiomeric purity. however, accessing the "unnatural" enantiomer of product is often difficult without tailored enzymes.
wikipedia
9ea3827cd2cb2c0154ae5f77d33747dac1fca6cc
the oxidation of aromatic compounds to dearomatized products
the oxidation of aromatic compounds to dearomatized products is a step in the processing of arenes. since seminal study by gibson on enzymes in pseudomonas putida, four classes of enzymes have been identified that accomplish arene oxidation to dihydrodiols:
wikipedia
89b98c97412e618e003f8798ec26b232215fd1d0
microbial arene oxidation (mao) refers to the process
microbial arene oxidation (mao) refers to the process by which microbial enzymes convert aromatic compounds into more oxidized products. the initial intermediates are arene oxides. a number of oxidized products are possible, the most commonly employed for organic synthesis are cis -1,2-dihydroxy-cyclohexa-3,5-dienes ("...
wikipedia
6846b773a7ee8e8a8a6c17c24592899bfbf61dff
homospermidine synthase is an enzyme with systematic name
homospermidine synthase is an enzyme with systematic name putrescine:putrescine 4-aminobutyltransferase (ammonia-forming). this enzyme catalyses the following chemical reaction the reaction of this enzyme occurs in three steps.
wikipedia
ce9511a3f3ffb9b8abd63b8ad5f2a0eb7de55e77
homospermidine synthase (ec 2.5.1.44) is an enzyme with
homospermidine synthase (ec 2.5.1.44) is an enzyme with systematic name putrescine:putrescine 4-aminobutyltransferase (ammonia-forming). this enzyme catalyses the following chemical reaction
wikipedia
2c0c49059b12f3855e64fb8bc3df4a9cc18722d3
he arrived in london on 10 july 1777.
he arrived in london on 10 july 1777. he became associated with sir joseph banks and, following the death of swedish naturalist daniel solander in 1782, was the librarian of the royal society and vice-president of the linnean society of london.
wikipedia
caaca8d08a1a29470b3a4a1b4d6de349ef5ad43d
dryander was born in gothenburg, sweden. he was
dryander was born in gothenburg, sweden. he was the son of carl leonard dryander and brita maria montin. he was a pupil of carl linnaeus at uppsala university. he entered lund university in 1778 and received his master of philosophy in 1778.
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c264c78cd627f31feb95c892f6063e48fe914086
in july 2010, acosta signed a one-year contract
in july 2010, acosta signed a one-year contract which would take him offshore to the k-league, as a summer transfer for daegu fc. he made his debut as a substitute in a 2 – 0 loss against the pohang steelers, and made a further substitute appearance the following week. acosta was a starter for the match against seongna...
wikipedia