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683e504890731168399bdef2ae12bba30073d9d6 | patrick m. regan taught at binghamton university 1997-2013 | patrick m. regan taught at binghamton university 1997-2013 and is currently a faculty member at the university of notre dame. he has also held positions at the university of canterbury in new zealand and boğaziçi university in istanbul, turkey. from 2004 to 2005, he also served as a fulbright scholar at the internation... | wikipedia |
b408f85449651308d408e6a1e25121a7a6117f2d | regan has traveled the world extensively. his research | regan has traveled the world extensively. his research has brought him to several conflict-ravaged including palestine and central america. his research has been funded by the national science foundation and the world bank. he is on the editorial boards of international studies quarterly and is an associate editor of t... | wikipedia |
5c2bd7dc50c8733da6e565439782809c282b0a2f | regan married margaret mitzel in june 1988 in | regan married margaret mitzel in june 1988 in bloomfield hills, michigan. their son, shane, was born in detroit, michigan in 1991 and their daughter, kaitlin, was born in christchurch, new zealand in 1994. | wikipedia |
e11e3d7135a773a302c7bd05a01038bd0e82122f | regan was born in dearborn, michigan and is | regan was born in dearborn, michigan and is one of five children born to michael and susanne regan. regan attended western michigan university for his bachelor's degree, new york university for his master's degree and university of michigan for his phd. he was also a member of the peace corps after receiving his underg... | wikipedia |
3f258d8ef8db8c73d53c9b0ec7f52d3e975dd6c1 | alkylglycerol monooxygenase (agmo) (ec 1.14.16.5) is an enzyme | alkylglycerol monooxygenase (agmo) (ec 1.14.16.5) is an enzyme that catalyzes the hydroxylation of alkylglycerols, a specific subclass of ether lipids. this enzyme was first described in 1964 as a pteridine-dependent ether lipid cleaving enzyme. in 2010 finally, the gene coding for alkylglycerol monooxygenase was disco... | wikipedia |
f1783e8eecf7007e6e8393c117dadf7b6c45a6b7 | the systematic name for this enzyme is 1-alkyl-sn-glycerol,tetrahydrobiopterin:oxygen | the systematic name for this enzyme is 1-alkyl-sn-glycerol,tetrahydrobiopterin:oxygen oxidoreductase. other names in use are glyceryl-ether monooxygenase, glyceryl-ether cleaving enzyme, glyceryl ether oxygenase, glyceryl etherase, and o-alkylglycerol monooxygenase. | wikipedia |
842eb70a2cfdba9c33f9002e8b9b4ab531016dca | alkylglycerol monooxygenase is a membrane-bound mixed-function oxidase and | alkylglycerol monooxygenase is a membrane-bound mixed-function oxidase and harbours a fatty acid hydroxylase motif. the iron is believed to be coordinated by a diiron center composed of eight histidines, which can be found in all enzymes containing this motif. | wikipedia |
7ccaed043b312673e0c8789e0796984ade39d40f | the unstable intermediate product 1-hydroxyalkyl-sn-glycerol rearranges into the | the unstable intermediate product 1-hydroxyalkyl-sn-glycerol rearranges into the fatty aldehyde and the free glycerol derivative. the fatty aldehyde is then further oxidized to the corresponding acid by fatty aldehyde dehydrogenase. | wikipedia |
72863f182147f121cad89fe82f271f8fa3765caf | alkylglycerol monooxygenase (agmo) (ec 1.14.16.5) is an enzyme | alkylglycerol monooxygenase (agmo) (ec 1.14.16.5) is an enzyme that catalyzes the hydroxylation of alkylglycerols, a specific subclass of ether lipids. this enzyme was first described in 1964 as a pteridine-dependent ether lipid cleaving enzyme. in 2010 finally, the gene coding for alkylglycerol monooxygenase was disco... | wikipedia |
224f13efa61ff3705d9ba1fc5c0466d5043dfeb5 | in quantum field theory, a quartic interaction is | in quantum field theory, a quartic interaction is a type of self-interaction in a scalar field. other types of quartic interactions may be found under the topic of four-fermion interactions. a classical free scalar field φ satisfies the klein–gordon equation. if a scalar field is denoted φ , a quartic interaction is re... | wikipedia |
c7a28f9bea77a4f6b8015ff401b4688436e2ed43 | a proof of uniqueness can be provided if | a proof of uniqueness can be provided if we note that the solution can be sought in the form φ = φ (ξ) {\displaystyle \varphi =\varphi (\xi)} being ξ = p ⋅ x {\displaystyle \xi =p\cdot x}. then, the partial differential equation becomes an ordinary differential equation that is the one defining the jacobi elliptic func... | wikipedia |
b538f87b5b0b573ab157816b334461970018c948 | these wave solutions are interesting as, notwithstanding we | these wave solutions are interesting as, notwithstanding we started with an equation with a wrong mass sign, the dispersion relation has the right one. besides, jacobi function d n {\displaystyle \,{\rm {dn}}\!} has no real zeros and so the field is never zero but moves around a given constant value that is initially c... | wikipedia |
711ee588046827adb135cc93eaf21dd87a75ce47 | since the z 2 {\displaystyle z_{2}} symmetry takes | since the z 2 {\displaystyle z_{2}} symmetry takes φ → − φ {\displaystyle \varphi \rightarrow -\varphi }, it must take | Ω + ⟩ ↔ | Ω − ⟩ {\displaystyle |\omega _{+}\rangle \leftrightarrow |\omega _{-}\rangle } as well.the two possible vacua for the theory are equivalent, but one has to be chosen. although it seems that... | wikipedia |
064466ad213704573a74603fd71525d6d4ddc205 | thinking in terms of vacuum expectation values lets | thinking in terms of vacuum expectation values lets us understand what happens to a symmetry when it is spontaneously broken. the original lagrangian was invariant under the z 2 {\displaystyle z_{2}} symmetry φ → − φ {\displaystyle \varphi \rightarrow -\varphi }. since | wikipedia |
491b5554f9fb89fd32b7586e825ff9f3662ce33d | an interesting feature can occur if m turns | an interesting feature can occur if m turns negative, but with λ still positive. in this case, the vacuum consists of two lowest-energy states, each of which spontaneously breaks the z global symmetry of the original theory. this leads to the appearance of interesting collective states like domain walls. in the o (2) t... | wikipedia |
d57c4f1319b52cbfe5f61b084d6ae76e0c676955 | the integrals over unconstrained momenta, called "loop integrals", | the integrals over unconstrained momenta, called "loop integrals", in the feynman graphs typically diverge. this is normally handled by renormalization, which is a procedure of adding divergent counter-terms to the lagrangian in such a way that the diagrams constructed from the original lagrangian and counterterms are ... | wikipedia |
17f3323d016fd32ac4f029a70a6b619fdabaf9c3 | the last rule takes into account the effect | the last rule takes into account the effect of dividing by z ~ {\displaystyle {\tilde {z}}}. the minkowski-space feynman rules are similar, except that each vertex is represented by − i λ {\displaystyle -i\lambda }, while each internal line is represented by a factor i /(q - m + i ε), where the ε term represents the sm... | wikipedia |
65bb3e4563e22879b22749f261b0ecb098ecbedd | the second two exponential factors can be expanded | the second two exponential factors can be expanded as power series, and the combinatorics of this expansion can be represented graphically. the integral with λ = 0 can be treated as a product of infinitely many elementary gaussian integrals, and the result may be expressed as a sum of feynman diagrams, calculated using... | wikipedia |
4742045eb174a4d1e2ace732be294625aa4b106d | the feynman diagram expansion may be obtained also | the feynman diagram expansion may be obtained also from the feynman path integral formulation. the time-ordered vacuum expectation values of polynomials in φ, known as the n -particle green's functions, are constructed by integrating over all possible fields, normalized by the vacuum expectation value with no external ... | wikipedia |
4ade767756faa99abb26454ceae35527ed67303e | the ϕ 4 {\displaystyle \phi ^{4}} model belongs | the ϕ 4 {\displaystyle \phi ^{4}} model belongs to the griffiths-simon class, meaning that it can be represented also as the weak limit of an ising model on a certain type of graph. the triviality of both the ϕ 4 {\displaystyle \phi ^{4}} model and the ising model in d ≥ 4 {\displaystyle d\geq 4} can be shown via a gra... | wikipedia |
5b032f48efd31644da76308f5266a85216614154 | in all of the models above, the coupling | in all of the models above, the coupling constant λ {\displaystyle \lambda } must be positive, since otherwise the potential would be unbounded below, and there would be no stable vacuum. also, the feynman path integral discussed below would be ill-defined. in 4 dimensions, ϕ 4 {\displaystyle \phi ^{4}} theories have a... | wikipedia |
a68f7904a834259afeb00de5801097eaf7d22c8e | which is thus equivalent to the so(2) model | which is thus equivalent to the so(2) model of real scalar fields φ 1, φ 2 {\displaystyle \varphi _{1},\varphi _{2}}, as can be seen by expanding the complex field ϕ {\displaystyle \phi } in real and imaginary parts. | wikipedia |
d62c1440e2e02c3dced8fcc268d166f9f0efeeb5 | the lagrangian for a complex scalar field can | the lagrangian for a complex scalar field can be motivated as follows. for two scalar fields φ 1 {\displaystyle \varphi _{1}} and φ 2 {\displaystyle \varphi _{2}} the lagrangian has the form | wikipedia |
3389d6bb157f31514d02acb81778acb921c20831 | in quantum field theory, a quartic interaction is | in quantum field theory, a quartic interaction is a type of self-interaction in a scalar field. other types of quartic interactions may be found under the topic of four-fermion interactions. a classical free scalar field φ {\displaystyle \varphi } satisfies the klein–gordon equation. if a scalar field is denoted φ {\di... | wikipedia |
414da67db9c7391d9155e06bcaaa2d6b88f228bf | the 2012 damallsvenskan, part of the 2012 swedish | the 2012 damallsvenskan, part of the 2012 swedish football season, was the 25th season of damallsvenskan since its establishment in 1988. the 2012 fixtures were released on 8 december 2011. the season began on 9 april 2012 and ended on 3 november 2012. ldb fc malmö were the defending champions, having won their 7th tit... | wikipedia |
ac6f561a80a4df1b1c93c50f8031fed4bfb53979 | hammarby if dff and dalsjöfors goif were relegated | hammarby if dff and dalsjöfors goif were relegated at the end of the 2011 season after finishing in the bottom two places of the table. they were replaced by division 1 division champions aik and vittsjö gik. | wikipedia |
ca03f02477e83e9270b6bb510c44e8341833fbf1 | the 2012 damallsvenskan, part of the 2012 swedish | the 2012 damallsvenskan, part of the 2012 swedish football season, was the 25th season of damallsvenskan since its establishment in 1988. the 2012 fixtures were released on 8 december 2011. the season began on 9 april 2012 and ended on 3 november 2012. ldb fc malmö were the defending champions, having won their 7th tit... | wikipedia |
a9d14af388f611d5bc1790a482bd34fd0c05e99d | michael doughty is a former australian rules footballer | michael doughty is a former australian rules footballer who played for the adelaide football club in the australian football league (afl) between 2000 and 2012. he is now playing for reynella football club in the southern football league, where he played junior football. originally from south adelaide football club in ... | wikipedia |
89d1503e078e09284d799f2d351b305deac4ea0e | known as a solid utility player, doughty has | known as a solid utility player, doughty has most often used as a midfielder, tagger or a small defender. doughty played his 150th game in round 8, 2009 and his 200th game in round 15, 2011. adelaide defeated sydney by seven points to end a record-equalling six-match losing streak in this match. he retired at the end o... | wikipedia |
7f3fe1537998121a4da4cbbefa0c89bc769f4652 | originally from south adelaide football club in the | originally from south adelaide football club in the south australian national football league (sanfl), doughty was drafted by adelaide with their first choice (fourth overall) at the 1999 rookie draft and elevated to adelaide's senior list in 2000 when he made his senior afl debut. | wikipedia |
36ae28865f092006ab021caaa5178f697fbce967 | michael doughty (born 5 august 1979) is a | michael doughty (born 5 august 1979) is a former australian rules footballer who played for the adelaide football club in the australian football league (afl) between 2000 and 2012. he is now playing for reynella football club in the southern football league, where he played junior football. | wikipedia |
72ef999efcd46fa32ee322e7d729b3be56bba590 | the 2014–15 all-ireland senior club hurling championship was | the 2014–15 all-ireland senior club hurling championship was the 45th staging of the all-ireland championship since its establishment in 1970. the championship began on 12 october 2014 and ended on 17 march 2015. portumna were the defending champions. ballyhale shamrocks won the title after a 1-18 to 1-6 win against ki... | wikipedia |
8778de457d2cc257604679206e2c102e83d09e07 | the 2014–15 all-ireland senior club hurling championship was | the 2014–15 all-ireland senior club hurling championship was the 45th staging of the all-ireland championship since its establishment in 1970. the championship began on 12 october 2014 and ended on 17 march 2015. | wikipedia |
195a9e3d2a5c0ac43dab9fce1bade4acd5af2e71 | pei songzhi (372–451), courtesy name shiqi, was a | pei songzhi (372–451), courtesy name shiqi, was a chinese historian and politician who lived in the late eastern jin dynasty and the liu song dynasty. his ancestral home was in wenxi county, shanxi, but he moved to the jiangnan region later. he is best known for making annotations to the historical text records of the ... | wikipedia |
0371fff16be472e4e654a5aa268f955a159356a2 | pei songzhi's father is pei gui (裴圭), son | pei songzhi's father is pei gui (裴圭), son of pei mei (裴昧). pei mei's great-grandfather is pei kang (裴康). pei kang, along with his older brother pei li (裴黎), and younger brothers pei kai (裴楷) and pei chuo (裴绰) were famous during their time and were known as the "4 peis". | wikipedia |
296d764c73d28c5b195f67783b8b3ba1e2d84e79 | pei songzhi is a member of the pei | pei songzhi is a member of the pei clan of hedong (河东裴氏). his son is pei yin, father of pei zhaoming (裴昭明; fl. 460 - 502), father of pei ziye. through his mother, pei songzhi is a great-grandson of the powerful jin regent yu liang. | wikipedia |
d4c76c5f41e60ea972eff8c015ef8cf5c371e20a | apart from making annotations to the sanguozhi, pei | apart from making annotations to the sanguozhi, pei also wrote other books such as the jin ji (晉紀; history of jin), pei shi jiazhuan (裴氏家傳; pei family biographies), and ji zhu sang fu jing zhuan (集注喪服經傳). | wikipedia |
1488a072d3e4cbfab9bf8920fe8579e2222966b3 | emperor wen of the liu song dynasty felt | emperor wen of the liu song dynasty felt that the historical text records of the three kingdoms (sanguozhi), written by chen shou in the third century, was too brief, so he commissioned pei to make annotations to the text. pei collected various sources, including those previously rejected by chen shou, and added them t... | wikipedia |
ef3d6f8276ba5f4f83eb240045bebc384915610a | in his later years, pei served as the | in his later years, pei served as the administrator of yongjia (永嘉太守), tongzhi sanqi changshi (通直散騎常侍), and administrator of south langya (南琅邪太守). pei retired from service at the age of 65 in 437. however, not long later, he was recalled back to the imperial court, and he served as attendant counsellor (中散大夫), state ac... | wikipedia |
f91eeecbd3f9174e60e3d0405ec7028c68e4f4a0 | liu yu usurped the throne in 420 and | liu yu usurped the throne in 420 and ended the eastern jin dynasty. he founded the liu song dynasty and became historically known as "emperor wu of liu song". pei took up various appointments in the liu song government, including secretary of the interior (內史) of lingling, state academician (國子博士) and rongcong puye (冗從... | wikipedia |
2d80571f9d4836adf58f12e07fbfe63ae2e9780d | in the early fifth century, pei served as | in the early fifth century, pei served as a regular mounted attendant (散騎侍郎) and later as the prefect (縣令) of guzhang county. he was recalled to the imperial court later and was promoted to shangshu ci bu lang (尚書祠部郎; a ceremonial official). in 416, the jin imperial court ordered liu yu, the duke of song, to lead a cam... | wikipedia |
c654b07294af6920b5e767ca99b7cf6fa28df556 | in 391, during the reign of emperor xiaowu, | in 391, during the reign of emperor xiaowu, pei became a palace general (殿中將軍) at the age of 20. in 398, during the reign of emperor an, pei's maternal uncle, yu kai (庾楷), who was the governor of yu province, allied with wang gong (王恭), the governor of yan and qing provinces, to attack the imperial capital, jiankang. t... | wikipedia |
fd0f5e389392f7c89e9a580eeea70eb77ac8deb2 | pei was born in a family of officials | pei was born in a family of officials who served in the eastern jin government. his grandfather, pei mei (裴昧), served as a household counsellor (光祿大夫) while his father, pei gui (裴珪), was a zheng yuanwailang (正員外郎). pei was fond of reading since his childhood, and he was already very familiar with classic texts such as ... | wikipedia |
195a9e3d2a5c0ac43dab9fce1bade4acd5af2e71 | pei songzhi (372–451), courtesy name shiqi, was a | pei songzhi (372–451), courtesy name shiqi, was a chinese historian and politician who lived in the late eastern jin dynasty and the liu song dynasty. his ancestral home was in wenxi county, shanxi, but he moved to the jiangnan region later. he is best known for making annotations to the historical text records of the ... | wikipedia |
3762386f70bc1adc61cbf9e948b57d1c2f0e7dfd | kemp left manchester city the following season, joining | kemp left manchester city the following season, joining sunderland 's academy while also playing for durham university's women's team. in 2018–2019 she was promoted to their first team, playing in the fa women's national league north. | wikipedia |
5422bd3f5e12d44dbde955147d6f694c932856a4 | arnault tzanck was a french physician and a | arnault tzanck was a french physician and a pioneer of blood transfusion. during the first world war, he was a doctor in the military ambulance where he realized the vital role of the blood transfusions. arnault tzanck's name is attached to an apparatus he invented that was widely used for transfusing blood in france b... | wikipedia |
98a307d18d62c25756ce967e7419d2a3a3bdeb04 | arnault tzanck's name is attached to an apparatus | arnault tzanck's name is attached to an apparatus he invented that was widely used for transfusing blood in france between the wars, as well as a simple test he devised using the microscopic analysis of scrapings from skin cancer lesions, different ganglia, and some forms of dermatitis especially pemphigus. the tzanck ... | wikipedia |
1034437b07b174f00244168f86747e39ff515541 | arnault tzanck (may 1, 1886 – february 18, | arnault tzanck (may 1, 1886 – february 18, 1954) was a french physician and a pioneer of blood transfusion. during the first world war, he was a doctor in the military ambulance where he realized the vital role of the blood transfusions. | wikipedia |
30bc9eded18732be5bc4962f15eb777ab7e62354 | a place cell is a kind of pyramidal | a place cell is a kind of pyramidal neuron in the hippocampus that becomes active when an animal enters a particular place in its environment, which is known as the place field. place cells are thought to act collectively as a cognitive representation of a specific location in space, known as a cognitive map. place cel... | wikipedia |
11c6a2bc8e7c14b935e26025daf34e427c064fa2 | aged rats further show a high instability in | aged rats further show a high instability in their place cells in the ca1 region. when introduced to the same environment several times, the hippocampal map of the environment changed about 30% of the time, suggesting that the place cells are remapping in response to the exact same environment. contrarily, the ca3 plac... | wikipedia |
0e67e8b94a6f8b16fa22f3eb0eb8b6737a815490 | this plasticity can be rescued in aged rats | this plasticity can be rescued in aged rats by giving them memantine, an antagonist that blocks the nmda receptors which is known to improve spatial memory, and was therefore used in an attempt to restore place field plasticity in aged subjects. nmda receptors, which are glutamate receptors, exhibit decreased activity ... | wikipedia |
746e777696412d7877fd624665a0d2b9755b291f | place field properties, including the rate of firing | place field properties, including the rate of firing and spike characteristics such as width and amplitude of the spikes, are largely similar between young and aged rats in the ca1 hippocampal region. however, while the size of place fields in the hippocampal ca3 region remains the same between young and aged rats, ave... | wikipedia |
8365a498ca0b592c870df08df533cff41dc1dd26 | problems with spatial memory and navigation are thought | problems with spatial memory and navigation are thought to be one of the early indications of alzheimer's disease. place cells have been shown to degenerate in alzheimer's mouse models, which causes such problems with spatial memory in these mice. furthermore, the place cells in these models have unstable representatio... | wikipedia |
5be2764994d84a47157ddea627b20db66bfd22e6 | place-related responses have been found in cells of | place-related responses have been found in cells of the japanese macaque and common marmoset, however, whether these are true place cells or spatial view cells is still debated. spatial view cells respond to locations that are visually explored by eye movement, or the "view of a space", rather than the location of the ... | wikipedia |
53aad10599c923125b8160657d859cd3c662f55e | place cells were reported in egyptian fruit bats | place cells were reported in egyptian fruit bats for the first time in 2007 by nachum ulanovsky and his lab. the place cells in bats have a place field in 3d, which is probably due to the bat flying in three dimensions. the place cells in bats can be based on either vision or echolocation, which remapping taking place ... | wikipedia |
c576ef0c789c121ce5638b6452b2fe544ba67728 | both rats and mice are often used as | both rats and mice are often used as model animals for place cells research. rats became especially popular after the development of multiarray electrodes, which allows for the simultaneous recording of a large number of cells. however, mice have the advantage that a larger range of genetic variants are available. addi... | wikipedia |
70b769d7a5b752ef06deab73f9d7e6df770535bf | place cells often exhibit reactivation outside their place | place cells often exhibit reactivation outside their place fields. this reactivation has a much faster time scale than the actual experience, and it occurs mostly in the same order in which it was originally experienced, or, more rarely, in reverse. replay is believed to have a functional role in memory retrieval and m... | wikipedia |
a333d2987dbcdd9c6f4184ad0431a280429073f5 | pattern separation is the ability to differentiate one | pattern separation is the ability to differentiate one memory from other stored memories. pattern separation begins in the dentate gyrus, a section of the hippocampus involved in memory formation and retrieval. granule cells in the dentate gyrus process sensory information using competitive learning, and relay a prelim... | wikipedia |
16b7bc4fe6eb54c937821618982e5536732ef0e9 | pattern completion is the ability to recall an | pattern completion is the ability to recall an entire memory from a partial or degraded sensory cue. place cells are able to maintain a stable firing field even after significant signals are removed from a location, suggesting that they can recall a pattern based on only part of the original input. furthermore, the pat... | wikipedia |
560b85e4233257622a5b1c4c345afd12cad135f2 | place cells play an important role in episodic | place cells play an important role in episodic memory. one important aspect of episodic memory is the spatial context in which the event occurred. hippocampal place cells have stable firing patterns even when cues from a location are removed and specific place fields begin firing when exposed to signals or a subset of ... | wikipedia |
d83d4a636528b7dd299e38b4d8179d511cdfee33 | movement can also be an important spatial cue. | movement can also be an important spatial cue. mice use their self-motion information to determine how far and in which direction they have travelled, a process called path integration. this is especially the case in the absence of continuous sensory inputs. for example, in an environment with a lack of visuospatial in... | wikipedia |
d2b73a391503e080d3d453600a6452b72c489aac | stimuli from the vestibular system, such as rotations, | stimuli from the vestibular system, such as rotations, can cause changes in place cells firing. after receiving vestibular input some place cells may remap to align with this input, though not all cells will remap and are more reliant on visual cues. bilateral lesions of the vestibular system in patients may cause abno... | wikipedia |
a846ac2b85d939c140189b19b2801253387201ca | although place cells primarily rely on visuospatial input, | although place cells primarily rely on visuospatial input, some studies suggest that olfactory input may also affect the formation and stability of place fields. olfaction may compensate for a loss of visual information, or even be responsible for the formation of stable place fields in the same way visuospatial cues a... | wikipedia |
d31ffff2f159bed234bd6a00d1199e601c49ed29 | spatial cues such as geometric boundaries or orienting | spatial cues such as geometric boundaries or orienting landmarks are important examples of metric input. an example is the walls of an environment, which provides information about relative distance and location. place cells generally rely on set distal cues rather than cues in the immediate proximal environment, thoug... | wikipedia |
de4630f3542d831859a61e95a8889088a7f68e4a | sensory information received by place cells can be | sensory information received by place cells can be categorized as either metric or contextual information, where metric information corresponds to where place cells should fire and contextual input corresponds to whether or not a place field should fire in a certain environment. metric sensory information is any kind o... | wikipedia |
e29a88b272cb934be68d4782f9d1057fddebcf55 | place cells were initially believed to fire in | place cells were initially believed to fire in direct relation to simple sensory inputs, but studies have suggested that this may not be the case. place fields are usually unaffected by large sensory changes, like removing a landmark from an environment, but respond to subtle changes, like a change in color or shape of... | wikipedia |
f17e5f87b1b669c5957bb37ce791252e3a4321a1 | in some cases place cells show directionality, meaning | in some cases place cells show directionality, meaning they will only fire in a location when the subject is travelling in a particular direction. however, they may also be omnidirectional, meaning they fire regardless of the direction the subject. the lack of directionality in some place cells might occur particularly... | wikipedia |
db6f7b65cbf81c50f4782a31466c7851d9ba7169 | the firing of place cells is timed in | the firing of place cells is timed in relation to local theta waves, a process termed phase precession. upon entering a place field, place cells will fire in bursts at a particular point in the phase of the underlying theta waves. however, as an animal progresses through the place field, the firing will happen progress... | wikipedia |
c377f17a9cd6e687e731d59eee3b3ecd66c38c46 | remapping refers to the change in the place | remapping refers to the change in the place field characteristics that occurs when a subject experiences a new environment, or the same environment in a new context. this phenomenon was first reported in 1987, and is thought to play a role in the memory function of the hippocampus. there are broadly two types of remapp... | wikipedia |
ad4c7828c2774683a4afb8fa6921b7c6a388f913 | place cells fire in a specific region of | place cells fire in a specific region of an environment, known as a place field. place fields are roughly analogous to the receptive fields of sensory neurons, in that the firing region corresponds to a region of sensory information in the environment. however, unlike receptive fields, place cells show no topography, m... | wikipedia |
8fbe3e1c6f1f3bdad745631c296556a6e999b2e4 | it has been proposed that place cells are | it has been proposed that place cells are derivatives of grid cells, pyramidal cells in the entorhinal cortex. this theory suggests that the place fields of the place cells are a combination of several grid cells, which have hexagonal grid-like patterns of activity. the theory has been supported by computational models... | wikipedia |
14137104edaf1414b15986b34eb6bc7aeac19884 | there has also been much debate as to | there has also been much debate as to whether hippocampal pyramidal cells truly encode non-spatial information as well as spatial information. according to the cognitive map theory, the hippocampus's primary role is to store spatial information through place cells and the hippocampus was biologically designed to provid... | wikipedia |
3ec229e26ba39aa419f5c6698ef0e058447561f6 | there has been much debate as to whether | there has been much debate as to whether hippocampal place cells function depends on landmarks in the environment, on environmental boundaries, or on an interaction between the two. additionally, not all place cells rely on the same external cues. one important distinction in cues is local and distal, where local cues ... | wikipedia |
c1707e667f9c7dc3e6ed5db2b8c077f78b446c57 | in 1976, o'keefe performed a follow-up study, demonstrating | in 1976, o'keefe performed a follow-up study, demonstrating the presence of what they called place units. these units were cells that fired in a particular place in the environment, the place field. they are described as having a low resting firing rate (<1 hz) when a rat is not in its place field, but a particularly h... | wikipedia |
ffad13f7279235f15677ab242ad94fa6c30bc964 | place cells were first discovered by john o'keefe | place cells were first discovered by john o'keefe and jonathan dostrovsky in 1971 in rats' hippocampuses. they noticed that rats with impairments in their hippocampus performed poorly in spatial tasks, and thus hypothesised that this area must hold some kind of spatial representation of the environment. to test this hy... | wikipedia |
d82936f5b9052f4aaf42bb1e7fa94d909dd0d82d | place cells are thought to play an important | place cells are thought to play an important role in episodic memory. they contain information about the spatial context a memory took place in. and they seem to perform consolidation by exhibiting replay – the reactivation of the place cells involved in a certain experience at a much faster timescale. place cells show... | wikipedia |
c3f7e0d00407b4afbbdc62e3954f928b4a702350 | place-cell firing patterns are often determined by stimuli | place-cell firing patterns are often determined by stimuli in the environment such as visual landmarks, and olfactory and vestibular stimuli. place cells have the ability to suddenly change their firing pattern from one pattern to another, a phenomenon known as remapping. this remapping may occur in either some of the ... | wikipedia |
3e59cc8add47857b623fb1a93ce5ea0ccb50edc1 | a place cell is a kind of pyramidal | a place cell is a kind of pyramidal neuron in the hippocampus that becomes active when an animal enters a particular place in its environment, which is known as the place field. place cells are thought to act collectively as a cognitive representation of a specific location in space, known as a cognitive map. place cel... | wikipedia |
41856cfa5d56ee6fb2fde5155d97de5c05e761ab | phospholipase a1 (ec 3.1.1.32; systematic name: phosphatidylcholine 1-acylhydrolase) | phospholipase a1 (ec 3.1.1.32; systematic name: phosphatidylcholine 1-acylhydrolase) encoded by the pla1a gene is a phospholipase enzyme which removes the 1-acyl group: it is an enzyme that resides in a class of enzymes called phospholipase that hydrolyze phospholipids into fatty acids. there are four classes, separate... | wikipedia |
3d83918a1843933b8db5d6e490a81f11b42a1ebb | in the early 1900s, an observation was made, | in the early 1900s, an observation was made, showing an accumulation of free fatty acids after incubation of pancreatic juice with phosphatidylcholine. one of the first cases of observed pla activity was on 1903 when snake venom was found to alter phosphatidylcholine into lysophosphatidylcholine, which is defined as a ... | wikipedia |
4ad3d8bab0d22cfa085fa7cd4d20ad51a55fe835 | unlike other phospholipases such as pla, there is | unlike other phospholipases such as pla, there is much that is unknown about pla due to the lack of any efficient way to purify, clone, express, and characterize this enzyme. pla is currently commercially unavailable because of this. lysophospholipids can be found as surfactants in food techniques and cosmetics, and ca... | wikipedia |
c99fde01db81b1f23b2d090deca78cdbfce8a386 | the structure of a pla is a monomer | the structure of a pla is a monomer that contains the following sequence: gly-x-ser-x-gly, where x represents any other amino acid. the serine is considered the active site in the enzyme. pla 's also contain a catalytic triad of ser-asp-his, with a variety of cysteine residues needed for disulfide bond formation. the c... | wikipedia |
69993cb13512e0a3a9cf875066a4f10c7d7aea1d | there are many variations of pla, differing slightly | there are many variations of pla, differing slightly between each organism it is present in. most notably, it can be found in mammalian cells such as plasma of rat livers and bovine brains, and can also be found in metazoan parasites, protozoan parasites, and snake venom. | wikipedia |
d6c6e592d47c2c3192dd2e1438c10da43dc233ab | pla 's are present in numerous species including | pla 's are present in numerous species including humans, and have a variety of cellular functions that include regulation and facilitation of the production of lysophospholipid mediators, and acting as digestive enzymes. these enzymes are responsible for fast turnover rates of cellular phospholipids. in addition to thi... | wikipedia |
73ebb25ce29b7349852f6ce40b6312dec098f0b0 | it is an enzyme that resides in a | it is an enzyme that resides in a class of enzymes called phospholipase that hydrolyze phospholipids into fatty acids. there are four classes, separated according to the type of reaction they catalyze. in particular, phospholipase a (pla) specifically catalyzes the cleavage at the sn -1 position of phospholipids, formi... | wikipedia |
f54404042788f717093d248e4e518a1ff50d8a3a | phospholipase a (ec 3.1.1.32; systematic name: phosphatidylcholine 1-acylhydrolase) | phospholipase a (ec 3.1.1.32; systematic name: phosphatidylcholine 1-acylhydrolase) encoded by the pla a gene is a phospholipase enzyme which removes the 1- acyl group: | wikipedia |
4a017b51f33d7aab8f36f5fe2b1042a404e92829 | the 2020–21 ghana women's premier league (gwpl) is | the 2020–21 ghana women's premier league (gwpl) is the top division league for women. the league was launched in 2012 and it is currently in its 8th season. hasaacas ladies were crowned champions after beating ampem darkoa fc 4–0 in the championship final. | wikipedia |
c556a2a6b9852f5854529fad5f61d522aa88b053 | the women's league went on a long break | the women's league went on a long break for the 2019–2020 season due to the covid-19 pandemic. the season for 2020–2021 was set to kick off on 15 january 2021. the league is played in two zones: the northern zone and the southern zone. winners of the northern and southern zones then meet in a championship final to decl... | wikipedia |
4a017b51f33d7aab8f36f5fe2b1042a404e92829 | the 2020–21 ghana women's premier league (gwpl) is | the 2020–21 ghana women's premier league (gwpl) is the top division league for women. the league was launched in 2012 and it is currently in its 8th season. hasaacas ladies were crowned champions after beating ampem darkoa fc 4–0 in the championship final. | wikipedia |
7287ce9e6d9287f0ef33378ad1efeefbdee0973b | "pra não dizer que não falei das flores", | "pra não dizer que não falei das flores", also known as "caminhando", is a song composed by geraldo vandré that ranked second in the iii festival internacional da canção in 1968. although it was the most applauded song of the night and very well received by the public, the music did not guarantee to vandré the prize th... | wikipedia |
079d177ad92073f35aab4c9a38e22d669d1505f2 | walking is still used to remember the situation | walking is still used to remember the situation that the country was going through at the time and to keep alive the memories of those who were victims of those hard times as occurred recently in the burial of antônio carlos bicalho lana, a 24-year-old student and one of the leaders of major resistance group aln, kille... | wikipedia |
6fd904f704d87b19cb9d943c2fe2d74483cc0742 | one of the most important brazilian songs and | one of the most important brazilian songs and an everlasting symbol of the resistance, caminhando is regarded by many as the true brazilian national hymn. writer and journalist millôr fernandes supports this hypothesis, saying that it was born during the fight and came being sung emotionally and in a spontaneous way by... | wikipedia |
00c638873043134d1e2d70fd0e2ce394570246a7 | one of the best known critiques of the | one of the best known critiques of the time came from colonel octavio costa, whose article " as flores do vandré " ('vandré's flowers') spoke against the public and the singer that won the second place. at the end of the article, he noted that three injustices were committed that night - one by the jury, one by the pub... | wikipedia |
d23f42cbe3cfdca5e32363142e427c9c62a61309 | also, the song was considered an affront by | also, the song was considered an affront by the government, mainly at the part that vandré refers to the "old lesson" that was taught in the barracks; something that was also seen as a reference to the torture inflicted for those accused of subversion, the suspects were commonly taken to police stations and military in... | wikipedia |
94901df7bb3d035230fd7f7c95fce6182ae9f2d3 | the melody has a hymn and march rhythm, | the melody has a hymn and march rhythm, and the lyric, with the verses in an easy rhyme scheme (almost all of them end with the same syllable: " ão ", sounding like "oun" from the word "sound" and equivalent to "on" from "nation" in english), to aid memorization, was widely played. | wikipedia |
fac1f9d17e0e1a17863b48c1931e9ef2ffd50303 | " pra não dizer que não falei das | " pra não dizer que não falei das flores " (portuguese for "not to say that i haven't spoken about the flowers"), also known as "caminhando" (portuguese for "walking" or "going forward"), is a song composed by geraldo vandré that ranked second in the iii festival internacional da canção in 1968. although it was the mos... | wikipedia |
09c9e8ea9a8bcda0bd1a264682798c3efe0a1f5e | the 2019 superettan was part of the 2019 | the 2019 superettan was part of the 2019 swedish football season, and the 20th season of superettan, sweden's second-tier football division in its current format. a total of 16 teams contest the league. | wikipedia |
da690f8b28c14f1e53e4a9a080fe6beccc6974bc | the 13th-placed and 14th-placed teams of superettan met | the 13th-placed and 14th-placed teams of superettan met the two runners-up from 2019 division 1 (norra and södra) in two-legged ties on a home-and-away basis with the teams from superettan finishing at home. | wikipedia |
0524db4276f056e7e1374240e3c87279e4193c4c | this is the last season that all teams | this is the last season that all teams will be obligated to have the logo of the league sponsor svenska spel on their jersey, as unibet will become the main league sponsor starting in 2020. teams are also required to wear the superettan logo on the right sleeve of their jerseys. | wikipedia |
7c7e081fdbce87d6e1441cebd96afe78d20e85ac | a total of 16 teams contest the league. | a total of 16 teams contest the league. the top two teams qualify directly for promotion to allsvenskan, the third will enter a play-off for the chance of promotion. the two bottom teams are automatically relegated, while the 13th and 14th placed teams will compete in a play-off to determine whether they are relegated. | wikipedia |
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