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80228906_80228935-28.layout.json
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507051678_507051691-12.layout.json
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0060132598-21.layout.json
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80228906_80228935-4.layout.json
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2064814997_4998-1.layout.json
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514050868+-0907-13.layout.json
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50517337-7342-5.layout.json
[ "December", "1989", "2.", "10,", "ja", "12,", "13.", "14.", "15.", "18,", "17.", "18,", "19.", "20.", "Helin", "JH,", "Edgington", "TS.", "Cyclosporin-A", "regulates", "monocyte/mac-", "rophage", "effector", "functions", "by", "affecting", "instructor", "T", "cells:", "inhi-", "bition", "of", "monocyte", "procoagulant", "response", "to", "allogeneic", "stimula-", "tion.", "J", "Immunol", "1984;", "132:", "1074,", ".", "Tutschka", "PT,", "Hess", "AD,", "Beschorner", "WE.", "Cyclosporine", "in", "clinical", "marrow", "transplantation:", "the", "Baltimore", "experience.", "Transplant", "Proc", "1982;", "16:", "2613.", ".", "Iwatsuki", "S,", "Starzl", "TE,", "Shaw", "BW,", "et", "al.", "Long-term", "use", "of", "cyclo-", "sporine", "in", "liver", "recipients.", "Transplantation", "1983;", "36:", "641.", ".", "Hardesty", "RL,", "Griffith", "BP,", "Debski", "RF,", "Bahnson", "HT.", "Experience", "with", "cyclosporine", "in", "cardiac", "transplantation.", "Transplant", "Proc", "1983;", "15:", "2553.", ".", "Ayer", "PE,", "Stinson", "EB,", "Jamieson", "SW,", "et", "al.", "Cyclosporine", "in", "cardiac", "transplantation:", "a", "2", "1/2", "year", "follow-up.", "Transplant", "Proc", "1983;", "15:", "2546.", ".", "Tilney", "NL,", "Milford", "EL,", "Araujo", "J,", "Strom", "TR,", "Carpenter", "CB,", "Kirkman", "RL.", "Experience", "with", "cyclosporine", "and", "steroids", "in", "clin-", "ical", "renal", "transplantation.", "Ann", "Surg", "1984;", "200:", "605,", ".", "Green", "CJ.", "Experimental", "transplantation", "and", "cyclosporine.", "Trans-", "plantation", "1988;", "46:", "38.", ".", "Tutschka", "PJ,", "Beschorner", "WE,", "Hess", "AD,", "Santos", "GW.", "Cyclospor-", "ine-A", "to", "prevent", "graft-versus", "disease:", "a", "pilot", "study", "in", "22", "patients", "receiving", "allogeneic", "marrow", "transplants.", "Blood", "1983;", "61:", "318.", "Santos", "GW,", "Tutschka", "PJ,", "Brookmeyer", "R,", "et", "al.", "Cyclosporine", "plus", "methyprednisolone", "as", "prophylaxis", "for", "graft-versus-host", "disease:", "a", "randomized", "double", "blind", "study", "in", "patients", "undergoing", "alloge-", "neic", "marrow", "transplantation.", "Clin", "Transplant", "1987;", "1:", "21.", "Hess", "AD,", "Vogelsang", "GB,", "Silanskis", "M,", "Friedman", "KA,", "Beschorner", "WE,", "Santos", "GW.", "Syngeneic", "graft-versus-host", "disease", "after", "allo-", "geneic", "bone", "marrow", "transplantation", "and", "eyclosporine", "treatment.", "Transplant", "Proc", "1988;", "20:", "487.", "Glazier", "A,", "Tutschka", "PJ,", "Farmer", "ER,", "Santos", "GW.", "Graft-versus-", "host", "disease", "in", "cyclosporin", "A-treated", "rats", "after", "syngeneic", "and", "autologous", "bone", "marrow", "reconstitution.", "J", "Exp", "Med", "1983;", "158:", "1.", "Sorokin", "R,", "Kimura", "H,", "Schroder", "K,", "Wilson", "DH,", "Wilson", "DB.", "Cyclosporine-induced", "sutoimmunity:", "conditions", "for", "expressing", "disease,", "requirement", "for", "intact", "thymus,", "and", "potency", "estimates", "of", "autoimmune", "lymphocytes", "in", "drug-treated", "rats.", "J", "Exp", "Med", "1986;", "164:", "1615,", "Cheney", "RT,", "Sprent", "J.", "Capacity", "of", "cyclosporine", "to", "induce", "auto-", "graft-versus-host", "disease", "and", "impair", "intrathymic", "T", "cell", "differ-", "entiation.", "Transplant", "Proc", "1985;", "17:", "528.", "Chow", "LH,", "Mosbach-Ozmen", "L,", "Ryffel", "B,", "Borel", "JF.", "Syngeneic", "graft-", "versus-host", "disease", "induced", "by", "cyclosporine—a", "reappraisal.", "Transplantation", "1988;", "46:", "107S.", "Jenkins", "MK,", "Schwartz", "RH,", "Pardoll", "DM.", "Effects", "of", "cyclosporine", "A", "on", "T", "cell", "development", "and", "clonal", "deletion.", "Science", "1988;", "241:", "1655.", "Gao", "E,", "Lo", "D,", "Cheney", "R,", "Kanagawa", "O,", "Sprent", "J.", "Abnormal", "differ-", "entiation", "of", "thymocytes", "in", "mice", "treated", "with", "cyclosporin", "A.", "Nature", "1988;", "336:", "176.", "Bos", "GMJ,", "Majoor", "GD,", "van", "Breda-Vriesman", "PJC.", "Cyclosporin", "A", "induces", "a", "selective,", "reversible", "suppression", "of", "T-helper", "lympho-", "cyte", "regeneration", "after", "syngeneic", "bone", "marrow", "transplantation:", "association", "with", "syngeneic", "graft-versus-host", "disease", "in", "rats.", "Clin", "Exp", "Immunol", "1988;", "74:", "443.", "Hess", "AD,", "Horwitz", "L,", "Beschorner", "WE,", "Santos", "GW.", "Development", "of", "graft-vs.-host", "disease-like", "syndrome", "in", "cyclosporine-treated", "rats", "after", "syngeneic", "bone", "marrow", "transplantation:", "I.", "Develop-", "ment", "of", "cytotoxic", "T", "lymphocytes", "with", "apparent", "polyclonal", "anti-", "Ia-specificity,", "including", "autoreactivity.", "J", "Exp", "Med", "1985;", "161:", "718.", "Beschorner", "WE,", "Shinn", "CA,", "Fischer", "AC,", "Santos", "GW,", "Hess", "AD.", "Cyclosporine-induced", "pseudo-graft-versus-host", "disease", "in", "the", "early", "post-cyclosporine", "period.", "Transplantation", "1988;", "46:", "1128,", "BRYSON", "ET", "AL.", "21.", "22.", "23,", "24.", "25.", "26.", "27,", "28.", "29.", "30", "31.", "32", "33.", "35.", "386,", "37.", "1047", ".", "Nagarkatti", "PS,", "Snow", "EC,", "Kaplan", "AM.", "Characterization", "and", "fune-", "tion", "of", "autoreactive", "T-lymphocyte", "clones", "isolated", "from", "normal,", "unprimed", "mice.", "Cell", "Immunol", "1985;", "94:", "32.", "Nagarkatti", "PS,", "Nagarkatti", "M,", "Kaplan", "AM.", "Normal", "Lyt1*2\"", "T", "cells", "have", "the", "unique", "capacity", "to", "respond", "to", "syngeneic", "autoreactive", "T", "cells:", "demonstration", "of", "a", "T", "cell", "network.", "J", "Exp", "Med", "1985;", "162:", "375,", "Nagarkatti", "PS,", "Nagarkatti", "M,", "Mann", "LW,", "Jones", "LA,", "Kaplan", "AM.", "Characterization", "of", "an", "endogenous", "Lyt", "2*", "T-suppressor-cell", "pop-", "ulation", "regulating", "autoreactive", "T", "cells", "in", "vitro", "and", "in", "vivo.", "Cell", "Immunol", "1988;", "112:", "64.", "Mason", "DW,", "Dallman", "M,", "Barclay", "AN.", "Graft-versus-host", "disease", "induces", "expression", "of", "Ia", "antigen", "in", "rat", "epidermal", "cells", "and", "gut", "epithelium.", "Science", "1981;", "293:", "150.", "Besch(?rner", "WE,", "Di", "Gennarl?", "KA,", "Hess", "AD,", "Santos", "GW.", "Cyclo-", "sporine", "and", "the", "thymus:", "influence", "of", "irradiation", "and", "age", "on", "thymic", "immunopathology", "and", "recovery.", "Cell", "Immunol", "1987;", "110:", "350.", "Rappaport", "H,", "Khalil", "A,", "Halle-Pannenko", "O,", "Pritchard", "L,", "Dantchev", "D,", "Mathé", "G.", "Histopathologic", "sequence", "of", "events", "in", "adult", "mice", "undergoing", "fethal", "graft-versus-host", "reaction", "developed", "across", "H-", "2", "and/or", "non-H-2", "histocompatibility", "barriers.", "Am", "J", "Pathol", "1979;", "96:121.", "Seemayer", "TA,", "Lapp", "WS,", "Bolande", "RP.", "Thymic", "involution", "in", "mu-", "rine", "graft-versus-host", "reaction.", "Am", "J", "Pathol", "1977;", "88:", "119,", "Van", "Elven", "EH,", "Rolink", "AG,", "van", "der", "Veen", "F,", "Gleichman", "E.", "Capacity", "of", "genetically", "different", "T", "lymphocytes", "to", "induce", "lethal", "graft-", "versus-host", "disease", "correlates", "with", "their", "capacity", "to", "generate", "suppression", "but", "not", "with", "their", "capacity", "to", "generate", "anti-F,", "killer", "cells:", "a", "non-H-2", "locus", "determines", "the", "inability", "to", "induce", "lethal", "graft-versus-host", "disease.", "J", "Exp", "Med", "1981;", "152:", "1474.", "Halle-Pannenko", "O,", "Pritchard", "LL,", "Bruley-Rosset", "M,", "Berumen", "L,", "Motta", "R.", "Parameters", "involved", "in", "the", "induction", "and", "abrogation", "of", "the", "letal", "graft-versus-host", "reaction.directed", "against", "non-H-2", 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"210.", "Glazier", "A,", "Tutschka", "PJ,", "Farmer", "E.", "Studies", "on", "the", "immunobiology", "of", "syngeneic", "and", "autologous", "graft-versus-host", "disease", "in", "cyclo-", "sporine-treated", "rats.", "In:", "Kahan", "BD,", "ed.", "Cyclosporine:", "biological", "activity", "in", "clinical", "applications,", "vol.", "1.", "New", "York:", "Grune", "&", "Stratton,", "1984:", "819.", "Pullen", "AM,", "Marrack", "P,", "Kappler", "JW.", "The", "T-cell", "repertoire", "is", "heavily", "influenced", "by", "tolerance", "to", "polymorphic", "self-antigens.", "Nature", "1988;", "335:", "796.", "MacDonald", "HR,", "Schneider", "R,", "Lees", "RK,", "et", "al.", "T-cell", "receptor", "Vg", "use", "predicts", "reactivity", "and", "tolerance", "to", "Mls*-encoded", "antigens.", "Nature", "1988;", "332:", "40,", "Kappler", "JW,", "Staerz", "U,", "White", "J,", "Marrack", "PC.", "Seli-tolerance", "elim-", "inates", "T", "cells", "specific", "for", "Mls-modified", "products", "of", "the", "major", "histocompatibility", "complex.", "Nature", "1988;", "332:", "35.", "Received", "3", "May", "1989.", "Accepted", "19", "July", "1989," ]
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524860047+-0116-51.layout.json
[ "Research", "—", "State", "of", "The", "Busingss", "2000", "4:30", "M", "TUESDAY", "55,", "THE", "ANALYSIS", "OF", "SIDESTREAM", "ODOR", "PROFILE", "BY", "VOC", "PRECON-", "CENTRATER/GC-O", "TECHNIQUES.", "Nobukazu_", "Higashi,", "Tobacco", "Science", "Research", "Center,", "Japan", "Tobacco", "Inc.,", "6-2,", "Umegaoka,", "Aoba-ku,", "Yokohama,", "227-", "8512", "JAPAN.", "Various", "techniques", "were", "employed", "for", "the", "analysis", "of", "volatile", "organic", "compounds", "(VOCs).", "However,", "these", "techniques", "were", "not", "sufficient", "for", "precise", "analysis", "of", "smoke", "VOCs", "because", "of", "complex", "handling,", "system", "instability,", "poor", "sensitivity", "and", "reproducibility.", "To", "overcome", "these", "problems,", "we", "introduced", "a", "combined", "system", "of", "VOC", "preconcentrater,", "gas", "chromatograph,", "and", "olfactometer.", "We", "evaluated", "the", "performance", "of", "this", "new", "system", "for", "the", "analysis", "of", "VOCs", "in", "tobacco", "smoke", "and", "applied", "it", "to", "odor", "profiling", "of", "sidestream", "smoke,", "which", "was", "not", "sufficiently", "investigated", "in", "the", "past.", "The", "VOC", "sample", "in", "a", "gas-sampling", "bag", "was", "injected", "to", "gas", "chromatograph", "through", "the", "preconcentrater,", "in", "which", "it", "was", "concentrated,", "dehydrated", "and", "cryo-focused.", "Separated", "VOCs", "were", "introduced", "into", "mass", "spectrometer", "and", "into", "the", "sniffing", "port", "(for", "odor", "profiling)", "by", "a", "splitting", "device.", "The", "power", "of", "the", "odor", "was", "estimated", "based", "on", "the", "dilution", "ratio", "of", "the", "sample", "(Aroma", "Dilution", "Analysis:", "ADA).", "This", "system", "showed", "sufficient", "performance", "for", "the", "analysis", "of", "VOCs.", "The", "reproducibility", "of", "quantification", "was", "good", "enough", "with", "CV", "value", "less", "than", "5%", "(n=5)", "and", "the", "detection", "limit", "was", "10ng/cigaretie.", "Using", "the", "GC-O", "method,", "we", "obtained", "sidestream", "odor", "profile", "that", "included", "over", "30", "odor", "characteristics.", "ADA", "results", "indicated", "that", "7", "odor", "characteristics", "had", "enough", "power", "to", "describe", "sidestream", "odor.", "In", "addition,", "the", "sensory", "test", "revealed", "that", "3", "odor", "characteristics", "(metallic,", "potato,", "and", "nutty)", "were", "most", "important", "for", "the", "description", "of", "sidestream", "odor.", "5:00", "em", "ADJOURN", "TUESDAY", "AFTERNQON,", "SEPTEMBER", "26,", "2000", "SESSION", "B", "SESSIONS", "CHAIR:", "RICHARD", "R,", "BAKER", "1:30", "pM", "TUESDAY", "56.", "CIGARETTE", "IGNITABILITY", "OF", "TREATED", "SAILCLOTH,", "DUCK", "AND", "COMMERCIAL", "FABRICS.", "Ioscph", "Wanna,", "Brown", "&", "Williamson", "Tobacco", "Corp.,", "Macon,", "GA", "31202-1056,", "USA", "Commercial", "upholstery", "fabrics", "span", "a", "wide", "range", "of", "areal", "density,", "fiber", "composition,", "ion", "content,", "air", "permeability,", "weave", "construction,", "and", "texture.", "Preliminaty", "surveys", "indicated", "that", "fabric", "arcal", "density,", "ion", "content,", "and", "air", "permeability", "have", "the", "largest", "influence", "on", "its", "ignitability", "when", "exposed", "10", "a", "smoldering", "cigarette.", "Duck", "fabrics", "with", "high", "areal", "density,", "cation", "content,", "and", "low", "air", "permeability", "can", "be", "representative", "of", "one", "end", "of", "commercial", "fabrics.", "A", "surrogate", "fabric", "is", "required", "to", "0", "52486", "0098" ]
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2071327810_7819-3.layout.json
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500692166_500692218-51.layout.json
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509790579+-0598-9.layout.json
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0071018341-0.layout.json
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511781859_511781868-1.layout.json
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2046807567_7643-69.layout.json
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0060254218.layout.json
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2072389710a.layout.json
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2045346283.layout.json
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tob12612.65_tob12612.66-0.layout.json
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521115419+-5436-5.layout.json
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500441172+-1192-5.layout.json
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2057448810_2057448813-1.layout.json
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0001039501-110.layout.json
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521115419+-5436-3.layout.json
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524485248+-5257-8.layout.json
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