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2022161585_2022161648-61.layout.json | [
"From:",
"Subject:",
"Plans",
"and",
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"for",
"1981",
"PHILIP",
"MORRIS",
"INCORPORATED",
"INTER-OFFICE",
"CORRESPONDENCE",
"RICHMOND,",
"VIRGINIA",
".",
"Dr.",
"W.",
"A.",
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"A.",
"Cliff",
"Lilly",
"The",
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"a",
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"for",
"me",
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"Please",
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"people",
"from",
"several",
"areas",
"in",
"R&D",
"and",
"other",
"departments",
"in",
"Richmond",
"Operations.",
"The",
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"are",
"listed",
"in",
"order",
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"A.",
"TOBACCO",
"FILLING",
"POWER",
"IMPROVEMENT",
"Objective:",
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"the",
"mechanism",
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"filling",
"power",
"improvement",
"by",
"heat",
"treating",
"and",
"to",
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"use",
"of",
"the",
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"Plans:",
"This",
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"is",
"off",
"to",
"a",
"good",
"start",
"in",
"cooperation",
"with",
"J.",
"Banyasz,",
"P.",
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"H.",
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"will",
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"the",
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"activity",
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"overwetting",
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"if",
"the",
"effect",
"passes",
"through",
"the",
"cutting",
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"and",
"if",
"the",
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"helps",
"prevent",
"reordering",
"collapse",
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"the",
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"and",
"faster",
"heating",
"methods",
"must",
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"to",
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"in",
"making",
"the",
"process",
"commercial.",
"REDUCED",
"CO",
"CIGARETTES",
"Objective:",
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"the",
"present",
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"results",
"on",
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"will",
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"we",
"expect",
"to",
"start",
"experimental",
"work",
"in",
"the",
"first",
"quarter",
"of",
"1981.",
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"T",
"and",
"Abstracts",
"mutagenicity",
"or",
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"Bangalore",
"560",
"058,",
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"India",
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"pipe)",
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"2",
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"smoked",
"in",
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"about",
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"arcas",
"from",
"1.8",
"to",
"1L.1",
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"in",
"rural",
"areas",
"from",
"4",
"to",
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"University.",
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"the",
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"smoking,",
"other",
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"are",
"air",
"pol-",
"lution,",
"Tiving",
"conditions,",
"biomass",
"fuel",
"used",
"for",
"cooking,",
"climatic",
"conditions,",
"dusty",
"environment,",
"etc,",
"It",
"is",
"difficult",
"to",
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"to",
"only",
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"many",
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"are",
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"at",
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"even",
"more",
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"relative",
"risk",
"ratios,",
"unless",
"the",
"confounding",
"factors",
"are",
"prop-",
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"controlled.",
"These",
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"have",
"not",
"controlled",
"for",
"various",
"compounding",
"fac-",
"tors",
"especially",
"pollution",
"related",
"factors.",
"These",
"and",
"other",
"interesting",
"facts",
"will",
"be",
"discussed",
"in",
"this",
"paper",
"based",
"on",
"a",
"review",
"of",
"the",
"literature,",
"Noon",
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"Schroder",
"K,",
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524860047+-0116-51.layout.json | [
"Research",
"—",
"State",
"of",
"The",
"Busingss",
"2000",
"4:30",
"M",
"TUESDAY",
"55,",
"THE",
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"TECHNIQUES.",
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"Science",
"Research",
"Center,",
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"Tobacco",
"Inc.,",
"6-2,",
"Umegaoka,",
"Aoba-ku,",
"Yokohama,",
"227-",
"8512",
"JAPAN.",
"Various",
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"employed",
"for",
"the",
"analysis",
"of",
"volatile",
"organic",
"compounds",
"(VOCs).",
"However,",
"these",
"techniques",
"were",
"not",
"sufficient",
"for",
"precise",
"analysis",
"of",
"smoke",
"VOCs",
"because",
"of",
"complex",
"handling,",
"system",
"instability,",
"poor",
"sensitivity",
"and",
"reproducibility.",
"To",
"overcome",
"these",
"problems,",
"we",
"introduced",
"a",
"combined",
"system",
"of",
"VOC",
"preconcentrater,",
"gas",
"chromatograph,",
"and",
"olfactometer.",
"We",
"evaluated",
"the",
"performance",
"of",
"this",
"new",
"system",
"for",
"the",
"analysis",
"of",
"VOCs",
"in",
"tobacco",
"smoke",
"and",
"applied",
"it",
"to",
"odor",
"profiling",
"of",
"sidestream",
"smoke,",
"which",
"was",
"not",
"sufficiently",
"investigated",
"in",
"the",
"past.",
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"VOC",
"sample",
"in",
"a",
"gas-sampling",
"bag",
"was",
"injected",
"to",
"gas",
"chromatograph",
"through",
"the",
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"in",
"which",
"it",
"was",
"concentrated,",
"dehydrated",
"and",
"cryo-focused.",
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"VOCs",
"were",
"introduced",
"into",
"mass",
"spectrometer",
"and",
"into",
"the",
"sniffing",
"port",
"(for",
"odor",
"profiling)",
"by",
"a",
"splitting",
"device.",
"The",
"power",
"of",
"the",
"odor",
"was",
"estimated",
"based",
"on",
"the",
"dilution",
"ratio",
"of",
"the",
"sample",
"(Aroma",
"Dilution",
"Analysis:",
"ADA).",
"This",
"system",
"showed",
"sufficient",
"performance",
"for",
"the",
"analysis",
"of",
"VOCs.",
"The",
"reproducibility",
"of",
"quantification",
"was",
"good",
"enough",
"with",
"CV",
"value",
"less",
"than",
"5%",
"(n=5)",
"and",
"the",
"detection",
"limit",
"was",
"10ng/cigaretie.",
"Using",
"the",
"GC-O",
"method,",
"we",
"obtained",
"sidestream",
"odor",
"profile",
"that",
"included",
"over",
"30",
"odor",
"characteristics.",
"ADA",
"results",
"indicated",
"that",
"7",
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"had",
"enough",
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"3",
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"and",
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"the",
"description",
"of",
"sidestream",
"odor.",
"5:00",
"em",
"ADJOURN",
"TUESDAY",
"AFTERNQON,",
"SEPTEMBER",
"26,",
"2000",
"SESSION",
"B",
"SESSIONS",
"CHAIR:",
"RICHARD",
"R,",
"BAKER",
"1:30",
"pM",
"TUESDAY",
"56.",
"CIGARETTE",
"IGNITABILITY",
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"SAILCLOTH,",
"DUCK",
"AND",
"COMMERCIAL",
"FABRICS.",
"Ioscph",
"Wanna,",
"Brown",
"&",
"Williamson",
"Tobacco",
"Corp.,",
"Macon,",
"GA",
"31202-1056,",
"USA",
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"fabrics",
"span",
"a",
"wide",
"range",
"of",
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"density,",
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"composition,",
"ion",
"content,",
"air",
"permeability,",
"weave",
"construction,",
"and",
"texture.",
"Preliminaty",
"surveys",
"indicated",
"that",
"fabric",
"arcal",
"density,",
"ion",
"content,",
"and",
"air",
"permeability",
"have",
"the",
"largest",
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"exposed",
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"a",
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"density,",
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"and",
"low",
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"of",
"one",
"end",
"of",
"commercial",
"fabrics.",
"A",
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"fabric",
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"0",
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0071018341-0.layout.json | [
"628",
"FroMm",
"CONFIDENTIAL",
"MEMDRANDUM",
"T",
"Amsrivan",
"Tollcso",
"Copany",
"Mr,",
"R.",
"K.",
"Heimann",
"DPATE",
"November",
"10,",
"1967",
"Executive",
"Vice",
"President",
"J.",
"H.",
"Hager,",
"Coordinator,",
"New",
"Products",
"Division",
"Research",
"and",
"Development",
"SusJEeT",
"Weekly",
"Progress",
"Report",
"Production",
"schedules",
"next",
"week",
"for",
"new",
"products",
"include",
"10",
"million",
"BULL",
"DURHAM,",
"70",
"million",
"TAREYTON",
"100's,",
"8",
"million",
"SILVA",
"THINS",
"100's,",
"240",
"thousand",
"TENNYSON",
"CONVERTIBLE",
"100's,",
"240",
"thousand",
"TENNYSON",
"Menthol",
"85",
"mm",
"and",
"120",
"thousand",
"FIFTY",
"FIFTY",
"cigavettes.",
"TAREYTON",
"100's",
"Tests",
"are",
"being",
"run",
"in",
"Durham",
"to",
"prove",
"out",
"the",
"full",
"implications",
"and",
"economic",
"feasibllity",
"of",
"the",
"change",
"from",
"the",
"20",
"mm",
"filter",
"to",
"the",
"25",
"mm",
"filter",
"on",
"TAREYTON",
"100's,",
"In",
"this",
"process",
"they",
"are",
"resolving",
"questions",
"concerning",
"speeds",
"and",
"filter",
"rod",
"lengthe.,",
"From",
"the",
"tests",
"they",
"are",
"stockpiling",
"rods",
"as",
"well,",
"and",
"the",
"change",
"will",
"probably",
"be",
"made",
"in",
"cigarette",
"production",
"in",
"a",
"few",
"weeks",
"after",
"the",
"tests",
"are",
"completed,",
"It",
"1s",
"my",
"understanding",
"that",
"the",
"model",
"cipgarettes",
"with",
"the",
"25",
"mm",
"filter",
"were",
"satisfactory,",
"and",
"that",
"you",
"are",
"agreeable",
"to",
"the",
"change,",
"IENNYSON",
"CONVERTIBLE",
"100's",
"The",
"first",
"factory",
"run",
"on",
"single",
"piece",
"convertible",
"filters",
"was",
"not",
"successful,",
"as",
"the",
"filter",
"tip",
"production",
"machine",
"being",
"used",
"was",
"too",
"rough",
"on",
"the",
"rods",
"in",
"making",
"the",
"cigarettes,",
"However,",
"a",
"newer",
"filter",
"tip",
"machinery",
"modification",
"shows",
"promise",
"of",
"easier",
"handling",
"of",
"the",
"rods",
"during",
"production.",
"We",
"plan",
"to",
"make",
"a",
"repeat",
"run",
"with",
"the",
"different",
"machinery",
"to",
"obtain",
"the",
"much",
"better",
"cigarettes",
"promised",
"to",
"you",
"for",
"evaluation",
"and",
"paneling.",
"This",
"prototype",
"pro-",
"duction",
"experience",
"is",
"also",
"necessary",
"to",
"put",
"us",
"in",
"a",
"position",
"for",
"expanding",
"the",
"concept",
"itfito",
"larger",
"scale",
"practical",
"production",
"of",
"clgarettes.",
"As",
"for",
"the",
"fabrication",
"of",
"filter",
"rods,",
"work",
"om",
"building",
"a",
"precision",
"unit",
"is",
"well",
"underway",
"now,with",
"the",
"help",
"of",
"the",
"Gemeral",
"Engineering",
"Department,",
"to",
"ensble",
"us",
"to",
"expand",
"beyond",
"pilot",
"plant",
"capacity",
"in",
"rod",
"making",
"and",
"to",
"yield",
"better",
"quality",
"single",
"pilece",
"convertible",
"filter",
"rods",
"with",
"menthol",
"capsules.",
"PROJECT",
"K",
"This",
"week",
"there",
"was",
"much",
"activity",
"in",
"the",
"laboratories",
"at",
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"and",
"Process",
"Development",
"in",
"the",
"pursult",
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"solutions",
"to",
"the",
"fundamental",
"problems",
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"rough",
"and",
"scratchy",
"taste,",
"poor",
"burning",
"characteristics",
"and",
"undesirable",
"sidestream",
"aroma.",
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"from",
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"will",
"be",
"applied",
"in",
"a",
"new",
"machine",
"run",
"of",
"ersatz",
"material",
"at",
"PDL,",
"probably",
"within",
"the",
"next",
"week",
"or",
"so.",
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"work",
"centers",
"around",
"base",
"sheet",
"formulation",
"changes",
"and",
"additional",
"additives,",
"e.g.,",
"the",
"removal",
"of",
"kraft",
"fiber",
"and",
"inclusion",
"of",
"other",
"meals",
"in",
"the",
"formula,",
"and",
"the",
"addition",
"of",
"compounds",
"related",
"to",
"volatile",
"oils",
"found",
"in",
"tobacco."
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511781859_511781868-1.layout.json | [
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2046807567_7643-69.layout.json | [
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"168-267.",
"DRAFT",
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"NOT",
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"QUOTATION",
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"ATTRIBUTION.",
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"tors",
"in",
"the",
"American",
"Cancer",
"Society's",
"sur-",
"vey",
"o",
"smokers.",
"Whereas",
"the",
"ACS",
"reporis",
"smokers",
"had",
"seven",
"times",
"the",
"reported",
"lung",
"cancer",
"death",
"rate",
"of",
"men",
"who",
"never",
"smoked,",
"Dr.",
"Berkson",
"wonders",
"about",
"twe",
"psychological",
"questions.",
"The",
"ACS",
"asked",
"a",
"€:oup",
"of",
"volunteers",
"to",
"have",
"their",
"friends",
"1il",
"out",
"forms",
"about",
"their",
"health",
"and",
"their",
"smoking",
"habits.",
"A",
"total",
"of",
"about",
"£30,000",
"men",
"between",
"the",
"ages",
"of",
"50",
"and",
"70",
"partici-",
"Pated",
"in",
"the",
"study.",
"As",
"these",
"died,",
"the",
"cause",
"of",
"their",
"death",
"was",
"ascertained",
"by",
"obtaining",
"a",
"cony",
"of",
"the",
"death",
"rerlificate",
"not",
"choose",
"to",
"take",
"part",
"in",
"the",
"tesis?",
"If",
"5o,",
"the",
"findings",
"would",
"be",
"distorted.",
"(2)",
"The",
"number",
"of",
"nonsmokers",
"whe",
"participated",
"i",
"the",
"studies",
"was",
"higher",
"than",
"the",
"percentage",
"of",
"nonsmokers",
"in",
"a",
"similar",
"group",
"amon;",
"the",
"population",
"as",
"a",
"whole;",
"does",
"this",
"sug-",
"gest",
"that",
"hesvy",
"smokers",
"might",
"have",
"refused",
"to",
"participate",
"in",
"the",
"survey?",
"That,",
"too,",
"‘would",
"have",
"distorted",
"the",
"results.",
"Statistics",
"can",
"be",
"tricky,",
"Sometimes",
"they",
"can",
"be",
"used",
"to",
"prove",
"anything.",
"Dr.",
"Berk-",
"son",
"has",
"performed",
"&",
"publie",
"service",
"in",
"poin!-",
"ing",
"aut",
"the",
"possibility",
"that",
"the",
"American",
"Cancer",
"Society",
"did",
"not",
"vonsider",
"the",
"human",
"factors",
"in",
"its",
"research,",
"STAR",
"Orlendo,",
"Fla.",
"August",
"15,",
"1955",
"Tobacco",
"And",
"Cancer",
"A",
"WIDOW",
"HAS",
"entered",
"suit",
"against",
"twh",
"of",
"America's",
"leading",
"tobacco",
"firms",
".in",
"the",
"sum",
"of",
"$779,500",
"claiming",
"the",
"use",
"of",
"cigarels",
"caused.",
"or",
"contributed",
"1o",
"the",
"growtn",
"ot",
"a",
"throat",
"cancer.",
"killing",
"her",
"husband.",
"However,",
"only",
"last",
"week",
"Dr.",
"Joseph",
"Berkson",
"of",
"the",
"Mayo",
"Clinic",
"reported",
"after",
"re-examination",
"of",
"data",
"collected",
"on",
"cancer",
"causes,",
"that",
"it",
"was",
"2",
"fallacy",
"to",
"charge",
"that",
"tobacco",
"had",
"been",
"the",
"cause",
"f",
"the",
"disease.",
"Dr,",
"Berkson",
"said",
"there",
"was",
"no",
"greater",
"proportion",
"of",
"cancer",
"victims",
"among",
"the",
"smoking",
"population",
"than",
"there",
"was",
"from",
"the",
"non-smoking",
"population.",
"He",
"said",
"the",
"same",
"mistake",
"had",
"been",
"made",
"in",
"the",
"tuberculosis-cancer-tabacco",
"research",
"re-",
"ports.",
"Be",
"that",
"as",
"it",
"may,",
"we",
"cannot",
"see",
"ihe",
"Justice",
"of",
"a",
"widow,",
"father",
"or",
"any",
"other",
"member",
"of",
"a",
"family",
"suing",
"a",
"tobacco",
"company",
"because",
"someone",
"was",
"thought",
"to",
"have",
"had",
"his",
"health",
"injured",
"from",
"smoking.",
"Man",
"is",
"a",
"free",
"agent.",
"No",
"tobacco",
"com-",
"pany",
"forces",
"smoking",
"upon",
"anyone.",
"Men",
"and",
"women",
"smoke",
"because",
"they",
"want",
"to.",
"It",
"would",
"make",
"as",
"much",
"sense",
"to",
"sue",
"4",
"liquor",
"manufacturer",
"because",
"someone.",
"drank",
"too",
"much.",
"No",
"one",
"has",
"done",
"yeat",
"yet.",
"JOURSAL",
"STAR",
"Peorie,",
"Ill.",
"Dr.",
"Berkson",
"rzises",
"these",
"questions.",
"{1}",
"The",
"death",
"rate",
"from",
"all",
"causes",
"was",
"lower",
"in",
"the",
"studies",
"than",
"the",
"death",
"rate",
"in",
"the",
"general",
"population",
"(considering",
"similar",
"groups);",
"did",
"this",
"indieate",
"that",
"men",
"who",
"knew",
"themselves",
"to",
"be",
"seriously",
"il",
"did",
"August",
"19,",
"1955",
"Nothiwe",
"Prozan",
"¥et",
"T",
"you",
"srevs",
"one-ume",
"£.205ex",
"who",
"quit",
"because",
"of",
"th~",
"lung",
"canrer",
"gaare,",
"relax.",
"Latc",
"Tepart",
"1s",
"that",
"no",
"one",
"has",
"yet",
"proven",
"anything.",
"A",
"Mayp",
"Clinic",
"doctor",
"rlaims",
"that",
"a",
"re-analysis",
"of",
"eatlier",
"Amerioen",
"Cancer",
"Soclety",
"studies",
"revealed",
"a",
"fallacy",
"and",
"that",
"con-",
"clusfons",
"drawn",
"from",
"those",
"stud.",
"ies",
"are",
"na",
"longer",
"valid,",
"He",
"saic",
"‘much",
"more",
"work”",
"needs",
"1o",
"b(",
"done",
"before",
"smoking",
"can",
"Anked",
"with",
"lung",
"cancer.",
"As",
"this",
"column",
"has",
"observec",
"sefore,",
"the",
"same",
"set",
"of",
"statistier",
"=an",
"often",
"be",
"used",
"to",
"prove",
"con",
"Tadictory,",
"mutua)ly-exclusive",
"al",
"legations,"
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"experiences,",
"the",
"tasks",
"defined",
"for",
"the",
"internship",
"are",
"designed",
"to",
"provide",
"enough",
"production",
"to",
"more",
"than",
"offset",
"the",
"initial",
"dilution",
"which",
"is",
"to",
"be",
"expected",
"when",
"adding",
"a",
"new",
"person",
"to",
"a",
"project.",
"These",
"tasks",
"focus",
"on",
"the",
"Release",
"Tape",
"and",
"on",
"reports",
"software",
"in",
"the",
"Physical",
"Testing",
"Laboratory.",
"The",
"following",
"explanations",
"are",
"given",
"to",
"assist",
"you",
"in",
"interpreting",
"the",
"schedules:",
"The",
"left",
"delimiter",
"marks",
"the",
"beginning",
"of",
"the",
"request's",
"time",
"frame.",
"The",
"right",
"delimiter",
"marks",
"the",
"projected",
"end.",
"Delimiters",
"which",
"have",
"been",
"filled",
"in",
"are",
"factual,",
"while",
"those",
"which",
"are",
"open",
"indicate",
"a",
"target.",
"Solid",
"lines",
"indicate",
"past",
"time",
"while",
"dotted",
"lines",
"indicate",
"future",
"time.",
"An",
"open",
"right",
"delimiter",
"with",
"a",
"solid",
"line",
"passing",
"through",
"it",
"indicates",
"a",
"target",
"which",
"has",
"not",
"been",
"met.",
"An",
"open",
"right",
"delimiter",
"which",
"is",
"in",
"the",
"past,",
"and",
"which",
"does",
"not",
"have",
"a",
"solid",
"line",
"passing",
"through",
"it,",
"indicates",
"a",
"request",
"which",
"is",
"as",
"complete",
"as",
"1is",
"possible",
"prior",
"to",
"some",
"action",
"by",
"some",
"other",
"request.",
"If",
"you",
"have",
"questions",
"or",
"comments,",
"please",
"call",
"me",
"at",
"Extension",
"3945.",
"'",
"i",
"2",
"fig::éhments",
"o",
"/%:T)45254£;5222§///",
"SEITIT2202"
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2046807567_7643-48.layout.json | [
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"(19411",
"E.",
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"ol,,",
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"(Suppl.",
"48)",
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"(1962)",
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"Natwre.",
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"1056-58",
"(1961}",
"Gardon,",
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"(1966)",
":",
"Invest.",
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"Shelley,",
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"dnn,",
"N.",
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"578-80",
"(1967)",
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"343-50",
"(1966)",
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"atwal,",
"LLIF",
"ADMINISTRATION",
"OF",
"AND",
"BEHAVIORAL",
"DEPENDENCE",
"ON",
"DRUGS!",
"By",
"C.",
"R.",
"Scnustee",
"anp",
"T.",
"Tuomrson",
"University",
"of",
"Michigan",
"Medical",
"School,",
"Ann",
"Arbor,",
"Michigon,",
"and",
"University",
"of",
"Minnesota",
"Medical",
"School,",
"Minneapolis,",
"Minnesota",
"INTRODUCTION",
"Man",
"Das",
"self-administered",
"chemical",
"substances",
"since",
"before",
"recarded",
"history",
"[Lewin",
"(1)].",
"When",
"an",
"individual",
"self-administers",
"an",
"illicit",
"or",
"a",
"fegal",
"drug",
"in",
"amounts",
"which",
"society",
"considers",
"excessive",
"or",
"inappropeiate,",
"the",
"terms",
"“drug",
"abuse”",
"and",
"“eddiction”",
"have",
"frequently",
"been",
"applied.",
"Ob-",
"jective",
"investigation",
"of",
"drug",
"self-administration",
"has",
"been",
"hampered",
"by",
"the",
"a",
"priori",
"moral",
"implications",
"inherent",
"in",
"these",
"terms.",
"It",
"has",
"become",
"increasingly",
"clear",
"that",
"a",
"scientific",
"understanding",
"of",
"drug",
"dependence",
"must",
"be",
"based",
"on",
"more",
"purely",
"descriptive",
"concepts",
"divested",
"of",
"such",
"moral",
"evaluations.",
"Since",
"1929",
"it",
"has",
"been",
"recognized",
"that",
"the",
"biological",
"factors",
"invoived",
"in",
"drug",
"de-",
"pendence",
"can",
"be",
"studicd",
"in",
"infra-human",
"organisms",
"[",
"Tatum,",
"Secvers",
"&",
"Collins",
"(2)1.",
"It",
"has,",
"however,",
"only",
"reccntly",
"heen",
"accepted",
"that",
"the",
"behavioral",
"aspects",
"of",
"drug",
"dependence",
"can",
"be",
"studied",
"in",
"infra-human",
"organisms.",
"Tn",
"addition",
"to",
"the",
"obvious",
"advantage",
"of",
"greater",
"cxperimental",
"control,",
"the",
"use",
"of",
"infra-",
"humar",
"organisms",
"has",
"another",
"mare",
"subtle",
"advantage.",
"The",
"investigator",
"using",
"organisms",
"is",
"less",
"likely",
"to",
"invoke",
"untestable",
"mentalistic",
"con-",
"structs",
"as",
"the",
"factors",
"generating",
"the",
"self-administration",
"of",
"drugs.",
"We",
"befieve",
"that",
"the",
"literature",
"regarding",
"the",
"behavioral",
"aspects",
"of",
"drig",
"dcpendence",
"can",
"most",
"profitably",
"be",
"interpreted",
"within",
"the",
"framework",
"of",
"op-",
"exant",
"conditioning",
"principles.",
"The",
"fandamental",
"principle",
"underlying",
"operant",
"conditioning",
"is",
"that",
"certain",
"aspects",
"of",
"behavior",
"are",
"controlled",
"by",
"their",
"consequiences.",
"Past",
"occurrence",
"of",
"certain",
"behavioral",
"consequences",
"contrals",
"the",
"fature",
"frequency",
"of",
"recurrence",
"or",
"pattern",
"of",
"behavior",
"or",
"both",
"which",
"produced",
"those",
"conscquences.",
"Behavior",
"controlted",
"by",
"its",
"consequences",
"is",
"termed",
"operant",
"behavior",
"and",
"the",
"cuntrotling",
"consequences",
"are",
"reinforcers.",
"A",
"drug",
"serving",
"as",
"»",
"controlling",
"consequence",
"for",
"the",
"operant",
"behavior",
"lead-",
"ing",
"to",
"its",
"administration",
"is",
"therefore",
"defined",
"as",
"2",
"reinforcer.",
"The",
"principal",
"goal",
"of",
"the",
"experimental",
"analysis",
"of",
"the",
"behavioral",
"aspects",
"of",
"drug",
"depen-",
"dence",
"is",
"to",
"determine",
"the",
"biological",
"and",
"environmental",
"variables",
"which",
"modify",
"a",
"drug’s",
"reinforcing",
"efficacy,",
"that",
"i,",
"the",
"extent",
"to",
"which",
"a",
"drug",
"is",
"self-administered",
"The",
"purpose",
"of",
"this",
"review",
"is",
"to",
"examine",
"the",
"classes",
"of",
"variables",
"which",
"Have",
"been",
"demonstrated",
"to",
"affect",
"the",
"sclf-administration",
"of",
"drugs.",
"*The",
"survey",
"of",
"fiterature",
"pertaining",
"to",
"this",
"review",
"was",
"concluded",
"in",
"June",
"1968,",
"483"
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"occupants",
"are",
"away",
"from",
"the",
"suspect",
"building.",
"SBS",
"symptoms",
"are",
"sometimes",
"classified",
"in",
"two",
"major",
"groups.",
"The",
"first",
"involves",
"sensory",
"reactions",
"such",
"as",
"irmitation",
"and",
"itching",
"of",
"the",
"eyes,",
"nose,",
"or",
"throat",
"often",
"accompanied",
"by",
"sensations",
"of",
"dryness",
"of",
"the",
"mucous",
"membrane",
"and",
"skin,",
"and",
"sometimes",
"by",
"erythema",
"(reddening)",
"of",
"the",
"skin.",
"The",
"second",
"set",
"are",
"systemic",
"effects",
"such",
"as",
"headache,",
"tiredness,",
"dizziness,",
"drowsiness,",
"or",
"digestive",
"disorders.",
"Studies",
"that",
"investigate",
"the",
"occurrence",
"and",
"correlates",
"of",
"the",
"separate",
"groups",
"appear",
"to",
"be",
"more",
"Tabie",
"1:",
"Types",
"of",
"Predominant",
"Environmental",
"Stressors",
"Source",
"Woods.",
"1488",
"Type",
"of",
"Environmental",
"Stressor",
"Frequency",
"(%)",
"Chemicat",
"and",
"particulate",
"contaminants",
"75",
"with",
"odour",
"discomfort",
"Thermal",
"discomfort",
"1",
"tow-",
"and",
"high-",
"relative",
"humidities",
"respectively)",
"Microbioiogical",
"contaminants",
"i",
"!",
"Nonthermal",
"humidity",
"problems",
"I",
"{with",
"eye",
"writation",
"and",
"mold",
"growth",
"from",
"70",
"S5",
"45",
"30",
"Table",
"2:",
"Frequencies",
"of",
"Occurrence",
"of",
"Physical",
"Causes",
"of",
"Problem",
"Buildings",
"(Scurce:",
"Woods.",
"1988}",
"Problem",
":",
"category",
"Physical",
"cause",
"Frequency",
"(%)",
"|",
"Dasign",
"System",
"probiems",
"!",
"+",
"Inadequate",
"outdoor",
"air",
"75",
"i",
"+",
"inadequate",
"air",
"distribution",
"to",
"!",
"occupied",
"spaces",
"(supply",
"and",
"return",
"devices)",
"75",
"Equipment",
"problems",
"+",
"Inadequate",
"filtration",
"of",
"supply",
"air",
"65",
"+",
"inadequate",
"drain",
"iines",
"and",
"drain",
"pans",
"&0",
"+",
"Contaminated",
"ductwork",
"or",
"duct",
"linings",
"45",
"«",
"Malfunctioning",
"humidifiers",
"20",
"Operations",
"*",
"Inappropriate",
"control",
"strategies",
"90",
"«",
"Inadequate",
"maintenance",
"75",
"«",
"Thermai",
"and",
"contaminant",
"load",
"changes",
"60\"",
"productive",
"than",
"those",
"that",
"group",
"all",
"SBS",
"symptoms",
"together.",
"Itisimportant",
"notonty",
"to",
"distinguish",
"different",
"forms",
"of",
"SBS,",
"but",
"also",
"to",
"distinguish",
"SBS",
"from",
"building-reiated",
"iliness",
"(BRI).",
"When",
"BRI",
"occurs,",
"SBS",
"often",
"occurs",
"as",
"waell,",
"according",
"to",
"Professor",
"James",
"Woods",
"of",
"Virginia",
"Polytachnic",
"Institute",
"in",
"Blacksburg,",
"Virginia.",
"What",
"Really",
"Causes",
"IAQ-Related",
"Compigints?",
"Woods,",
"amechanicatengineerand",
"physiologist,",
"conducted",
"numerous",
"investigations",
"directed",
"an",
"interdisciplinary",
"1AQ",
"investigatary",
"team.",
"Their",
"results",
"indicate",
"thatthere",
"are",
"usually",
"multipie",
"problems",
"that",
"could",
"be",
"causing",
"the",
"occupant",
"symptoms.",
"See",
"Tables",
"1",
"and",
"2",
"for",
"Woods'",
"results.",
"His",
"numbers",
"(given",
"in",
"per",
"cent)",
"add",
"up",
"to",
"more",
"than",
"100",
"because",
"he",
"includes",
"each",
"type",
"of",
"identified",
"problem",
"that",
"his",
"team",
"defines",
"as",
"potentially",
"contributing",
"to",
"the",
"complaints.",
"As",
"he",
"says,",
"there",
"is",
"usuaily",
"more",
"than",
"one",
"thing",
"wrong",
"with",
"a",
"probiem",
"building.",
"Woods’",
"data",
"indicate",
"that",
"ventilation",
"problems",
"often",
"exist",
"in",
"problem",
"buiidings,",
"but",
"they",
"alsoindicate",
"the",
"diverse",
"nature",
"of",
"the",
"contaminants",
"and",
"their",
"sources.",
"A",
"Bullding",
"Systems",
"Approach?",
"A",
"buikling",
"systems",
"approach",
"is",
"necessary,",
"but",
"it",
"means",
"something",
"differentfrom",
"what",
"BCIA",
"and",
"its",
"allies",
"mean.",
"The",
"approach",
"is",
"valuable",
"to",
"minimize",
"indoor",
"air",
"quality",
"problams",
"whaether",
"one",
"is",
"designing",
"a",
"building,",
"managing",
"and",
"operating",
"a",
"building,",
"or",
"investigating",
"a",
"probiem",
"attributed",
"10",
"POSr",
"indoor",
"air",
"quality.",
"A",
"proper",
"-building",
"systams",
"approach",
"shouid",
"mean",
"the",
"process",
"of",
"analyzing",
"a",
"building",
"as",
"a",
"dynamic,",
"complex",
"system",
"that",
"is",
"aftected",
"by",
"22",
"At",
"the",
"Centre,",
"August",
"1991",
"ceclessose"
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"parking.",
"Minirum",
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"17",
"eanons",
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"Lvands",
"solg",
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"100",
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"Cigareties",
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"point",
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"An",
"sgreed",
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"et",
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"primary",
"line",
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"sight",
"and",
"hianly",
"visitle,",
"Display",
"presence",
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"RIRT",
"full",
"prica",
"and",
"savings",
"bronds",
"will",
"exist",
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"bacidar",
"set.",
"Retailers",
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"the",
"above",
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"should",
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"Reprassntative.",
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"REQUIREMENTS:",
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"Pgsition",
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".",
".",
".",
"RJRT",
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"Spaca™",
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"ae",
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"visidle",
"merchandiaing",
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"ihat",
"Baging",
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"Az",
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"must",
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"height",
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"187",
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"fixture",
"untl",
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"lovel",
"ia",
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"ane",
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"twa",
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"1.",
"Featuro",
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"calculation",
"wilf",
"include",
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"spaca",
"sltocsted",
"(0",
"the",
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"st",
"the",
"W",
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"and",
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"af",
"ather",
"advertining",
"within",
"the",
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"set.",
"2.",
"Foaturs",
"space",
"calculalion",
"wil",
"exclude",
"(he",
"space",
"aticcates",
"(0",
"the",
"eanopy",
"at",
"thi",
"0P",
"of",
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"and",
"axclude",
"afl",
"ather",
"acvartiglng",
"within",
"the",
"marchandising",
"set",
"Ther",
"customer",
"checkou?",
"area",
"will",
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"8",
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"of",
"6\"",
"wida",
"with",
"2",
"proflle",
"of",
"marchandining",
"on",
"the",
"aefing",
"counter",
"no",
"highor",
"than",
"12\"",
"W",
"ensure",
"clear",
"visihility",
"of",
"the",
"RJRT",
"Featyre",
"Spaca.",
".",
"Retailer",
"will",
"parmit",
"RJRT",
"1o",
"chooze",
"the",
"utitization",
"of",
"RIAT",
"“Feotured",
"Spaca®",
"with",
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"tyna",
"and",
"advertising",
"siza",
"ang",
"cenfiguration,",
"RJIRT",
"will",
"hava",
"a",
"parmsnent",
"focation",
"(net",
"included",
"In",
"the",
"\"Featurad",
"Space”)",
"for",
"Valus",
"Added",
"Promotions",
"that",
"is",
"highly",
"viaible",
"1o",
"the",
"cansumer.",
"Retellar",
"will",
"Allocate",
"permanent",
"space",
"on",
"the",
"seling",
"coumer,",
"on",
"e",
"front",
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"selling",
"counter.",
"or",
"diractly",
"anove",
"the",
"paing",
"of",
"purehace",
"for",
"plecament",
"of",
"Value",
"Added",
"Promotian",
"communiestion.",
"RJRT",
"must",
"be",
"aflowed",
"lo",
"ptaca",
"price",
"cati~out",
"signage",
"equs!",
"to",
"ar",
"greater",
"than",
"ihe",
"number",
"of",
"piaces",
"placed",
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"is",
"competitors",
"off",
"of",
"the",
"merchandising",
"sol.",
"in",
"any",
"case,",
"RIKT",
"must",
"have",
"ihs",
"ability",
"to",
"place",
"a",
"minimum",
"of",
"two",
"pinces",
"of",
"signage",
"off",
"(he",
"2et.",
"acation",
"and",
"positiomng",
"of",
"this",
"signage",
"shall",
"be",
"detefmined",
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"RURT.",
"RJRT",
"rands",
"wil",
"occupy",
"“Festured",
"Space”",
"that",
"is",
"equal",
"to",
"RIRT",
"lars",
"SOM",
"of",
"RIRT",
"local",
"trading",
"SOM",
"or",
"35%,",
"whichevar",
"is",
"highest,",
"(b",
"any",
"<959,",
"RJRT",
"Faature",
"Space",
"will",
"not",
"Ue",
"leas",
"thap",
"nine",
"square",
"foet.",
"MC",
"Poritlon",
"Leve|",
"2",
"RJRT",
"brands",
"will",
"oscupy",
"“Faatured",
"Space”",
"that",
"is",
"squal",
"to",
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"slora",
"SOM",
"or",
"RIRT",
"local",
"trading",
"SOM",
"or",
"40%,",
"whichever",
"1s",
"highest,",
"ja",
"any",
"eage,",
"RIRT",
"Feature",
"Space",
"will",
"not",
"be",
"losa",
"than",
"tweive",
"squarc",
"feat.",
"MC",
"pPosition",
"Lavel",
"3",
"RJRT",
"brands",
"will",
"occupy",
"“Faglured",
"Space”",
"that",
"15",
"equal",
"ts",
"RJRY",
"utore",
"SOM",
"or",
"RIRT",
"local",
"trading",
"SOM",
"or",
"40%,",
"whichaver",
"je",
"ighest.",
"In",
"any",
"case,",
"RIRT",
"Faature",
"Space",
"will",
"not",
"be",
"leas",
"ivan",
"twelve",
"squam",
"foel.",
"RIRT",
"must",
"hava",
"the",
"abifily",
"to",
"pioca",
"3",
"nnimum",
"of",
"throe",
"pemnanant",
"ploces",
"of",
"aquily",
"signags",
"off",
"of",
"the",
"marchandising",
"sel.",
"The",
"actun!",
"number",
"of",
"piecos",
"reaquired",
"by",
"RIRT",
"will",
"be",
"delermiced",
"by",
"the",
"number",
"of",
"tata!",
"industry",
"piecas",
"pamitted.",
"from",
"which,",
"RIRT",
"gholl",
"have",
"a",
"percentage",
"st",
"is",
"aquai",
"10",
"or",
"grenter",
"than",
"aur",
"cordractad",
"space",
"but",
"no",
"10ss",
"than",
"3.",
"Lecatons",
"for",
"off",
"et",
"signage",
"will",
"include",
"Bxterior.",
"window",
"and",
"interior",
"lecatlons",
"at",
"RIRTs",
"request.",
"Valus",
"Added",
"Promation",
"communicatlon",
"must",
"be",
"a",
"pormanent",
"vehitlp",
"on",
"the",
"selfng",
"counter",
"al",
"the",
"point",
"of",
"purchase.",
"ADDITIONAL",
"MERCHANDISING/PRESENCE",
"REQUIREMENTS",
"Ve",
"ey",
"FORM",
"3803(rev:01/12/01)",
"Rotafiar",
"wilt",
"accept",
"Selivery",
"of,",
"asgemble",
"and",
"place",
"RIRT",
"promationsl",
"displays/advertising",
"In",
"a",
"tocation",
"highly",
"visible",
"to",
"congumers,",
"Retaiter",
"will",
"not",
"restrict",
"RIRTs",
"ability",
"to",
"displsy,",
"pramete",
"or",
"athsrwise",
"distributs",
"RIRT",
"brands",
"and",
"compare",
"agually",
"wilh",
"oiher",
"lobscco",
"companies",
"in",
"i",
"ataas",
"at",
"retail,",
"nor",
"will",
"ratatier",
"exclude",
"RIRT",
"from",
"displaying,",
"premoting",
"o",
"otherwise",
"diatibuting",
"RIRT",
"braade",
"during",
"any",
"pariod",
"i",
"which",
"this",
"sareament",
"is",
"jn",
"effect.",
"Retallor",
"will",
"not",
"reatrict",
"RJRT",
"s",
"ablity",
"to",
"place",
"temporary",
"squity",
"POS",
"material",
"(up",
"10",
"14",
"3quare",
"fél",
"In",
"5izs)",
"for",
"at",
"ioust",
"€",
"monthe",
"out",
"of",
"the",
"yosr,",
"1f",
"any",
"compatitive",
"displays",
"are",
"maintained",
"outside",
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"Ihe",
"back",
"bar",
"tobaéss",
"2ot",
"(e.g.",
"on",
"seitng",
"counter}",
"RIRT",
"Full",
"Price",
"Priority",
"Srand",
"Dleplay(z)",
"and/or",
"Savings",
"Friarity",
"Brand",
"dispidy",
"Will",
"be",
"mainteinad",
"to",
"match",
"full",
"price",
"andvor",
"3avings",
"compelitive",
"display(s).",
"Retailer",
"wil",
"affectively",
"communicate",
"Bl",
"RIRT",
"buy-down",
"activity",
"and",
"athar",
"promational",
"offess",
"10",
"the",
"condumer",
"via",
"brand",
"spacific",
"POS",
"as",
"approved",
"vy",
"RIRT.",
"Rotailar",
"will",
"pot",
"permit",
"additional",
"advertising",
"of",
"any",
"kind,",
"including",
"advertising",
"for",
"Retalier'a",
"own",
"products;",
"to",
"be",
"affixed",
"to",
"or",
"interfore",
"with",
"RIRT",
"contractad",
"spacm.",
"Retailar",
"will",
"agree",
"o",
"mainizin",
"front",
"countar",
"mefchendingr(s)equiprnent",
"at",
"an",
"accentable",
"height",
"us",
"tu",
"not",
"block",
"consumer",
"view",
"of",
"ina",
"backbar",
"tabacco",
"set.",
"RIRT",
"dioplays",
"and",
"advartising",
"may",
"nal",
"be",
"impaitad",
"or",
"obatrucied",
"from",
"view",
"of",
"consumers",
"by",
"competlitive",
"dispicys",
"or",
"by",
"any",
"ather",
"meons.",
"RJIRT",
"mecchandigers,",
"displays",
"snd",
"fraestanding",
"akinage",
"witl",
"be",
"Sl",
"as",
"designated",
"by",
"RJRT,",
"RJRT",
"5",
"abiity",
"10",
"adverntlse",
"price",
"will",
"be",
"ne",
"leas",
"than",
"parily",
"with",
"alher",
"participating",
"tehscro",
"compsaniss.",
".",
"RJIRT",
"teacrves",
"the",
"right",
"for",
"finel",
"approval",
"of",
"RIRT",
"&",
"diaplay",
"and",
"advertiaing",
"types,",
"sizas",
"and",
"locations.",
"Retaiet",
"will",
"maimain",
"displpy",
"and",
"advertising",
"spaca",
"mcesrding",
"1o",
"RIRT",
"nuthorized",
"plan-o-gram.",
"Changes",
"in",
"autharlzed",
"location",
"of",
"RIRT",
"dispisys",
"and",
"advertising,",
"or",
"their",
"lacation.",
"will",
"not",
"he",
"made",
"without",
"RJIRT",
"approval.",
"ITEM",
"NO.",
"846584(rev:01/12/01)",
"&5",
"Db",
"=Adsy",
"Lodhara",
"4",
"OO",
"Y",
"s",
"the",
"com.",
"office",
"00,3",
"2./~",
"O",
"[",
"Ll",
"79605786"
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"Emergency",
"and",
"First",
"Aid",
"Procedures:",
"B",
"Breathing:",
"REMOVE",
"PATIENT",
"TO",
"FRESH",
"AIR.",
"Eyes:",
"FLUSH",
"WITH",
"WATER",
"FOR",
"AT",
"LEAST",
"15",
"MINUTES.",
"Bkin:",
"WABH",
"WITH",
"S0AP",
"AND",
"WATER.",
"Swallowing:",
"CALL",
"PHYSICIAN",
"IMMEDIATELY.",
"DO",
"NOT",
"INDUCE",
"VOMITING.",
"#%%%%%%%%%%*%%fi%*%%**%%%*%%%fi**%§%**%%%%%%%%*%%%%%%%%%%*fi*%%%fi%fi%*%%*%%%%%*%*%%**%%%%",
"Stability:",
"STABLE",
"Conditions",
"to",
"Avoid:",
"DO",
"NOT",
"STORE",
"ABOVE",
"120",
"F",
"Incompatability",
"(NONE)",
",",
"Hazardous",
"Decomposition",
"Products",
"By",
"open",
"flame:",
"CARBON",
"MONOXIDE,",
"CARBON",
"DIOXIDE.",
"Hazardous",
"Polymerization:",
"WILL",
"NOT",
"QCCUR",
"TTSSTTLG08",
"SECTION",
"VI",
"REACTIVITY",
"DATA",
"%%%%%%fifi*%***%**fi%%*%%%%*%*%%*%*%*%%%%*%%fi**%*%4%*%*fi**%*fi*fifi*%%%**fififi%%*%%%***%%%%*;",
"{CONTINUEDR)"
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