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PMID:8822 | The acid--base status: a mathematical approach to its definition. | The respiratory and non-respiratory factors of acid--base status have been evaluated mathematically. New units of measurement for derangements of the acid--base balance are proposed. | The acid--base status: a mathematical approach to its definition. The respiratory and non-respiratory factors of acid--base status have been evaluated mathematically. New units of measurement for derangements of the acid--base balance are proposed. | [
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PMID:8823 | pH, temperature, humidity and the dynamic force-area curve of dipalmitoyl lecithin. | Both high pH at 25 degrees C and humidity at 37 degrees C prevent DPL films from attaining zero surface tension, whereas humidity at 25 degrees C and high pH at 37 degrees C do not. At 37 degrees C DPL lowered surface tension to zero when spread from organic solvent or when absorbed from aqueous 0.15 M NaCl in the surf... | pH, temperature, humidity and the dynamic force-area curve of dipalmitoyl lecithin. Both high pH at 25 degrees C and humidity at 37 degrees C prevent DPL films from attaining zero surface tension, whereas humidity at 25 degrees C and high pH at 37 degrees C do not. At 37 degrees C DPL lowered surface tension to zero wh... | [
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PMID:8829 | A micro-method for determination of fatty acid (FIAT) and glucose (GLIAT) incorporation and lipolysis in vitro in needle biopsies of human adipose tissue. | A method for determination of fatty acid (FIAT) and glucose (GLIAT) incorporation into adipose tissue in vitro in needle biopsy specimens of human fat has been developed. 20-150 mg of subcutaneous fat is incubated in an albumin buffer containing a physiological spectrum and concentration of fatty acids and glucose. Rel... | A micro-method for determination of fatty acid (FIAT) and glucose (GLIAT) incorporation and lipolysis in vitro in needle biopsies of human adipose tissue. A method for determination of fatty acid (FIAT) and glucose (GLIAT) incorporation into adipose tissue in vitro in needle biopsy specimens of human fat has been devel... | [
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PMID:8830 | Crohn's disease of the distal large bowel. | This study describes the clinical features and management of 80 patients with Crohn's disease affecting initially only the rectum with or without involvement of the sigmoid colon. Most patients were treated medically, and the various measures used are considered; the cumulative probability of completing five years unde... | Crohn's disease of the distal large bowel. This study describes the clinical features and management of 80 patients with Crohn's disease affecting initially only the rectum with or without involvement of the sigmoid colon. Most patients were treated medically, and the various measures used are considered; the cumulativ... | [
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PMID:8831 | Immunogenetic analysis of H-2 mutations. IV. Mapping of and immune reactions to the H-2fa mutation. | H-2fa is a spontaneous mutation that occurred in an (A.CA X A)F1 female mouse and was later transferred on an A-strain background [congenic line A.CA (M506) or M506]. Skin grafts exchanged between M506 and A.CA strains are rejected within 4 weeks after grafting. Significant reaction is observed when these two strains a... | Immunogenetic analysis of H-2 mutations. IV. Mapping of and immune reactions to the H-2fa mutation. H-2fa is a spontaneous mutation that occurred in an (A.CA X A)F1 female mouse and was later transferred on an A-strain background [congenic line A.CA (M506) or M506]. Skin grafts exchanged between M506 and A.CA strains a... | [
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PMID:8832 | Maternal immunocompetence. I. The graft-versus-host reactivity of lymphocytes from pregnant rats and the distribution pattern of 51Cr-labeled lymphocytes in pregnant mice. | Lymphocytes from the peripheral blood, spleen, or para-aortic lymph nodes of prrimigravida L rats carrying (L X BN) F1 (LBN) fetuses are fully capable of mounting graft-versus-host (GVH) reactions in LBN F1 recipients. The reactivity of lymphocytes from interstrain pregnant (L X BN) or intrastrain pregnant (L X L) rats... | Maternal immunocompetence. I. The graft-versus-host reactivity of lymphocytes from pregnant rats and the distribution pattern of 51Cr-labeled lymphocytes in pregnant mice. Lymphocytes from the peripheral blood, spleen, or para-aortic lymph nodes of prrimigravida L rats carrying (L X BN) F1 (LBN) fetuses are fully capab... | [
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PMID:8833 | Distribution of benorylate in plasma, synovial fluid and tissue in rheumatoid arthritis. | Six patients, not previously treated, with classical seropositive rheumatoid arthritis and highly active synovitis of one or both knee joints were treated with 4 g of 40% benorylate suspension twice daily for a period of 9--14 days prior to synovectomy. Blood samples were taken at scheduled times during administration ... | Distribution of benorylate in plasma, synovial fluid and tissue in rheumatoid arthritis. Six patients, not previously treated, with classical seropositive rheumatoid arthritis and highly active synovitis of one or both knee joints were treated with 4 g of 40% benorylate suspension twice daily for a period of 9--14 days... | [
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PMID:8834 | The passage of benorylate into the synovial fluid and tissue of rheumatoid patients. | After a preliminary wash-out period of 3-7 days during which no anti-inflammatory drugs were given, 11 female patients with classical or definite rheumatoid arthritis were given 8 g of benorylate as the 40% suspension 3-7 days prior to synovectomy of the knee. Samples of synovial tissue and fluid from the affected knee... | The passage of benorylate into the synovial fluid and tissue of rheumatoid patients. After a preliminary wash-out period of 3-7 days during which no anti-inflammatory drugs were given, 11 female patients with classical or definite rheumatoid arthritis were given 8 g of benorylate as the 40% suspension 3-7 days prior to... | [
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PMID:8835 | A long-term study of benorylate in patients with rheumatoid arthritis. | The analgesic and anti-inflammatory efficacy and adverse effects of benorylate were studied over a period of 6 months in 33 patients suffering from definite or classical rheumatoid arthritis. The average dose used was 6 g daily and examinations were made before treatment and at regular intervals during treatment to ass... | A long-term study of benorylate in patients with rheumatoid arthritis. The analgesic and anti-inflammatory efficacy and adverse effects of benorylate were studied over a period of 6 months in 33 patients suffering from definite or classical rheumatoid arthritis. The average dose used was 6 g daily and examinations were... | [
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PMID:8836 | A double-blind study of the analgesic action of benorylate suspension in osteoarthritis of the hip and knee. | This study compared benorylate suspension and placebo in a double-blind randomised cross-over design to investigate their analgesic effect in osteoarthritis of the hip and the knee. Benorylate and placebo were each given for 7 days. Assessment of efficacy and tolerance was carried out on the 7th day of each period. The... | A double-blind study of the analgesic action of benorylate suspension in osteoarthritis of the hip and knee. This study compared benorylate suspension and placebo in a double-blind randomised cross-over design to investigate their analgesic effect in osteoarthritis of the hip and the knee. Benorylate and placebo were e... | [
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PMID:8837 | Benorylate: a report on 2 years' experience of its use in rheumatoid arthritis and other chronic rheumatic diseases. | 52 outpatients with rheumatoid arthritis or osteoarthritis were given benorylate (as the 40% suspension) in doses of up to 8 g daily. Peroids of medication were varied but some patients were given the drug for nearly 2 years. Assessments of clinical progress were made at regular intervals by recording both subjective a... | Benorylate: a report on 2 years' experience of its use in rheumatoid arthritis and other chronic rheumatic diseases. 52 outpatients with rheumatoid arthritis or osteoarthritis were given benorylate (as the 40% suspension) in doses of up to 8 g daily. Peroids of medication were varied but some patients were given the dr... | [
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PMID:8838 | Clinical study of a new anti-inflammatory and analgesic compound, benorylate, in rheumatic disorders. | Benorylate is obtained by esterification of acetylsalicylic acid and N-acetyl p-aminophenol (4-acetamidophenyl 2-acetoxybenzoate). Experimentally, this new product has been shown to be a good analgesic and anti-inflammatory agent. A clinical trial was carried out in order to study the efficacy, side effects and toleran... | Clinical study of a new anti-inflammatory and analgesic compound, benorylate, in rheumatic disorders. Benorylate is obtained by esterification of acetylsalicylic acid and N-acetyl p-aminophenol (4-acetamidophenyl 2-acetoxybenzoate). Experimentally, this new product has been shown to be a good analgesic and anti-inflamm... | [
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PMID:8840 | A review of benorylate - a new antirheumatic drug. | Benorylate (Benoral, Benortan) is the esterification product of paracetamol and acetylsalicylic acid. It has anti-inflammatory, analgesic and antipyretic properties. Benorylate is probably absorbed as the intact molecule which accounts for its good gastric tolerance. After absorption, benorylate is hydrolysed into its ... | A review of benorylate - a new antirheumatic drug. Benorylate (Benoral, Benortan) is the esterification product of paracetamol and acetylsalicylic acid. It has anti-inflammatory, analgesic and antipyretic properties. Benorylate is probably absorbed as the intact molecule which accounts for its good gastric tolerance. A... | [
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PMID:8841 | Simultaneous pharmacokinetics of benorylate in plasma and synovial fluid of patients with rheumatoid arthritis. | Twenty patients with definite or classical rheumatoid arthritis and chronic knee effusions were each given an oral dose of 4 g benorylate as the 40% suspension. Synovial fluid and plasma samples were obtained up to 9 hours after drug administration and assayed for their salicylate and benorylate content. A mean peak be... | Simultaneous pharmacokinetics of benorylate in plasma and synovial fluid of patients with rheumatoid arthritis. Twenty patients with definite or classical rheumatoid arthritis and chronic knee effusions were each given an oral dose of 4 g benorylate as the 40% suspension. Synovial fluid and plasma samples were obtained... | [
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PMID:8842 | Muscle crossbridges: absence of direct effect of calcium on movement away from the thick filaments. | Fluorescence depolarization experiments show that the rotary mobility of myosin heads is hindered by the assembly of the thick filament. Calcium, with or without magnesium adenosine triphosphate, dose not alter this hindrance in synthetic filaments. This implies that calcium does not directly move the crossbridges towa... | Muscle crossbridges: absence of direct effect of calcium on movement away from the thick filaments. Fluorescence depolarization experiments show that the rotary mobility of myosin heads is hindered by the assembly of the thick filament. Calcium, with or without magnesium adenosine triphosphate, dose not alter this hind... | [
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PMID:8843 | [Identification of organic substances by means of spectral methods in forensic toxicology. I. Infrared spectroscopy]. | In the introduction the author gives an outline of the principles of infrared spectroscopy and possibilities of its use for the identification of organic substances. On examples from practice he demonstrates the use of infrared spectroscopy in forensic toxicology. He desribes methods for the isolation of substances fro... | [Identification of organic substances by means of spectral methods in forensic toxicology. I. Infrared spectroscopy]. In the introduction the author gives an outline of the principles of infrared spectroscopy and possibilities of its use for the identification of organic substances. On examples from practice he demonst... | [
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PMID:8844 | Recent advances in experimental leprosy. | Within the last 15 years we have learned to identify Mycobacterium leprae, determine its viability, screen the efficacy of antileprosy drugs, and monitor the bacilli for drug sensitivity. We have evidence that subclinical infections occur frequently among contacts of patients with leprosy and that the different manifes... | Recent advances in experimental leprosy. Within the last 15 years we have learned to identify Mycobacterium leprae, determine its viability, screen the efficacy of antileprosy drugs, and monitor the bacilli for drug sensitivity. We have evidence that subclinical infections occur frequently among contacts of patients wi... | [
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PMID:8845 | The survival of carp (Cyprinus carpio) outside water. | The possible use of the swimbladder of carp as auxiliary respiratory organ when the animals are exposed to air has been studied. After exposure to air, blood pH and pO2 and mean swimbladder O2 concentration decrease and blood pCO2 increases in normal animals. Exposure to air after ligation of the pneumatic ducts result... | The survival of carp (Cyprinus carpio) outside water. The possible use of the swimbladder of carp as auxiliary respiratory organ when the animals are exposed to air has been studied. After exposure to air, blood pH and pO2 and mean swimbladder O2 concentration decrease and blood pCO2 increases in normal animals. Exposu... | [
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PMID:8849 | The effects of mechanical preparation and acidification of the colon on the healing of colonic anastomoses. | The results of clinical studies have suggested that inadequate preoperative mechanical preparation of the colon is a significant factor in the pathogenesis of disruption of colonic and colorectal anastomoses. A possible explanation for the adverse effect of poor mechanical preparation is that ammonia released from fece... | The effects of mechanical preparation and acidification of the colon on the healing of colonic anastomoses. The results of clinical studies have suggested that inadequate preoperative mechanical preparation of the colon is a significant factor in the pathogenesis of disruption of colonic and colorectal anastomoses. A p... | [
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PMID:8858 | Higher activity of oxidative drug demethylation in the liver microsomes from dystrophic mouse. | The activities of NADPH-dependent oxidative demethylation of aminopyrine and other methyl compounds in the liver microsomes from dystrophic mice were found to be about 30% higher than those of the normal mice. Consumption of reduced pyridine nucleotides during the demethylation reactions was also significantly larger i... | Higher activity of oxidative drug demethylation in the liver microsomes from dystrophic mouse. The activities of NADPH-dependent oxidative demethylation of aminopyrine and other methyl compounds in the liver microsomes from dystrophic mice were found to be about 30% higher than those of the normal mice. Consumption of ... | [
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PMID:8859 | Non-adrenergic inhibition of the electrical activity of the antrum muscle fibers of the guinea-pig stomach. | The changes in the electrical activity of the antrum muscle fibers of the guinea pig stomach caused by ATP and its related compounds were compared with those caused by catecholamines. The antrum preparation exhibited spontaneous electrical activity and this was suppressed or inhibited by treatment with catecholamines (... | Non-adrenergic inhibition of the electrical activity of the antrum muscle fibers of the guinea-pig stomach. The changes in the electrical activity of the antrum muscle fibers of the guinea pig stomach caused by ATP and its related compounds were compared with those caused by catecholamines. The antrum preparation exhib... | [
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PMID:8860 | pH of amoebic liver pus. | Amoebic liver pus has an acidic pH. Hence the pleural aspirate from an amoebic empyema due to rupture of an amoebic liver abscess has an acidic pH. In contrast, the pH of pleural aspirates from effusions and empyema of non-amoebic aetiology were noted to have an alkaline pH. The clinical significance of these observati... | pH of amoebic liver pus. Amoebic liver pus has an acidic pH. Hence the pleural aspirate from an amoebic empyema due to rupture of an amoebic liver abscess has an acidic pH. In contrast, the pH of pleural aspirates from effusions and empyema of non-amoebic aetiology were noted to have an alkaline pH. The clinical signif... | [
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PMID:8862 | The differential diagnosis of bronchial asthma in children. | Bronchial asthma in children is not uncommon in the tropics. Conditions simulating this disease in the tropics have been discussed with a view to arriving at a diagnosis without sophisticated investigations. | The differential diagnosis of bronchial asthma in children. Bronchial asthma in children is not uncommon in the tropics. Conditions simulating this disease in the tropics have been discussed with a view to arriving at a diagnosis without sophisticated investigations. | [
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PMID:8864 | [Intermediate metabolism and respiratory function in peritonitis]. | During observations of 26 patients and in acute and chronic experiments on 31 dogs under conditions of peritonitis the author studied neurohumoral relations and the effect of hydrocortisone on the respiratory function. A conclusion is made on the vital importance of the consistent associated corrective neurohumoral the... | [Intermediate metabolism and respiratory function in peritonitis]. During observations of 26 patients and in acute and chronic experiments on 31 dogs under conditions of peritonitis the author studied neurohumoral relations and the effect of hydrocortisone on the respiratory function. A conclusion is made on the vital ... | [
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PMID:8863 | [Study of acid phosphatase II from Pichia guilliermondii yeasts]. | Acid phosphatase II (AP II) was isolated from the cell-free extract of Pichia guilliermondii Wickerham ATCC 9058 and partially purified. The enzyme is a non-specific phosphomonoesterase. It hydrolyzes p-nitrohenyl-phophate (NPP), beta-glycerophosphate, glucose-6-phosphate, guanosine-5'-monophosphate, adenosine-5'-monop... | [Study of acid phosphatase II from Pichia guilliermondii yeasts]. Acid phosphatase II (AP II) was isolated from the cell-free extract of Pichia guilliermondii Wickerham ATCC 9058 and partially purified. The enzyme is a non-specific phosphomonoesterase. It hydrolyzes p-nitrohenyl-phophate (NPP), beta-glycerophosphate, g... | [
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PMID:8867 | [Effect of physical and chemical factors on Pasteurella multocida bacteriophages]. | Studied was the effect of some physical factors (temperature, pH of various values) and some chemical ones (urea, sodium citrate, sarcolysin, methylene blue, acridine orange, pyronin, crystal violet, potassium permanganate, fuchsin, tetracycline and tetraolean) on phages specifically lysing Pasteurella multocida strain... | [Effect of physical and chemical factors on Pasteurella multocida bacteriophages]. Studied was the effect of some physical factors (temperature, pH of various values) and some chemical ones (urea, sodium citrate, sarcolysin, methylene blue, acridine orange, pyronin, crystal violet, potassium permanganate, fuchsin, tetr... | [
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PMID:8871 | Studies on new process procedures in plasma fractionation on an industrial scale. I. Determination of the pH value of ethanol containing protein solutions at low temperatures. | A suitable combined pH electode is evaluated which provides reproducible readings under the extreme conditions of the cold ethanol plasma fractionation procedure. Adequately reproducible correlations are found between the pH measurements in protein solutions with an ethanol content of up to 40% at temperatures as low a... | Studies on new process procedures in plasma fractionation on an industrial scale. I. Determination of the pH value of ethanol containing protein solutions at low temperatures. A suitable combined pH electode is evaluated which provides reproducible readings under the extreme conditions of the cold ethanol plasma fracti... | [
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PMID:8872 | Studies on new process procedures in plasma fractionation on an industrial scale. II. Experiments in concentrating dilute albumin solutions using hollow fiber ultrafiltration. | Ultrafiltration with a hollow fiber device was studied as an alternative method to the lyophilization or thin-layer distillation techniques in the production of salt-poor, concentrated human albumin preparations for clinical use. A number of process parameters are discussed. Combination of gel filtration and ultrafiltr... | Studies on new process procedures in plasma fractionation on an industrial scale. II. Experiments in concentrating dilute albumin solutions using hollow fiber ultrafiltration. Ultrafiltration with a hollow fiber device was studied as an alternative method to the lyophilization or thin-layer distillation techniques in t... | [
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PMID:8873 | [The influence of vitamin a, gentamicin and anoxaemia on urinary enzyme excretion (author's transl)]. | The excretion patterns of several urinary enzymes were investigated in the following four experimental groups of Wistar rats and compared with the normal range of each urinary enzyme studied. One group received vitamin A in high dosage; a second group was given vitamin A before and after bilateral clamping of the renal... | [The influence of vitamin a, gentamicin and anoxaemia on urinary enzyme excretion (author's transl)]. The excretion patterns of several urinary enzymes were investigated in the following four experimental groups of Wistar rats and compared with the normal range of each urinary enzyme studied. One group received vitamin... | [
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PMID:8874 | [Urinary enzyme levels in healthy human subjects and in rats (author's transl)]. | Urinary MDH, LDH, gamma-GT, LAP and muramidase levels were studied in 11 healthy persons with a wide age range and in 51 male Winstar rats weighing 300 to 400 g. Normal ranges of these urinary enzymes were determined and compared with the results of other authors. | [Urinary enzyme levels in healthy human subjects and in rats (author's transl)]. Urinary MDH, LDH, gamma-GT, LAP and muramidase levels were studied in 11 healthy persons with a wide age range and in 51 male Winstar rats weighing 300 to 400 g. Normal ranges of these urinary enzymes were determined and compared with the ... | [
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PMID:8877 | [Cellular immunity against bacteria (intracellular and extracellular parasites) in experimentally aged rats (author's transl)]. | The authors study the activity of RES in rats with Progeria-like syndrome of Selye, at the occasion of a repeated infection with bacteria--intracellular parasites (Brucella abortus 19) and bacteria--extracellular parasites (Diplococcus pneumoniae). They establish that immunization improves the activity of RES of the ex... | [Cellular immunity against bacteria (intracellular and extracellular parasites) in experimentally aged rats (author's transl)]. The authors study the activity of RES in rats with Progeria-like syndrome of Selye, at the occasion of a repeated infection with bacteria--intracellular parasites (Brucella abortus 19) and bac... | [
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PMID:8878 | [Resistance against intra- and extracellular bacteria in experimentally aged rats (author's transl)]. | The authors study the cellular activity of RES against the microbes intracellular and extracellular parasites in rats with pronounced Progeria-like syndrome of Selye. RES of the experimentally aged animals copes, through with a certain delay, with the invading extracellular bacterium Diplococcus pneumoniae, but is utte... | [Resistance against intra- and extracellular bacteria in experimentally aged rats (author's transl)]. The authors study the cellular activity of RES against the microbes intracellular and extracellular parasites in rats with pronounced Progeria-like syndrome of Selye. RES of the experimentally aged animals copes, throu... | [
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PMID:8879 | [Aminopeptidases in the serum and urine of patients with hyperthyroidism]. | In patients with hyperthyroidism the serum activities of the leucine aminopeptidase (LAP) and the alanine aminopeptidase (AAP) as well as the alanine aminopeptidase excretion in the urine were determined. A significantly increased activity of the leucine aminopeptidase in the serum and an increased excretion of alanine... | [Aminopeptidases in the serum and urine of patients with hyperthyroidism]. In patients with hyperthyroidism the serum activities of the leucine aminopeptidase (LAP) and the alanine aminopeptidase (AAP) as well as the alanine aminopeptidase excretion in the urine were determined. A significantly increased activity of th... | [
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PMID:8880 | [Vetorial presentation of left-ventricular pressure parameters for the assessment of ventricular function]. | The ventricle function can be established by the vectorial description of left-ventricular pressure parameters or flow sizes, respectively. The vector diagrammes result from the momentaneous pressure within the ventricle on the X-axis and the differentiated pressure curve or the aortic flow, respectively, on the Y-axis... | [Vetorial presentation of left-ventricular pressure parameters for the assessment of ventricular function]. The ventricle function can be established by the vectorial description of left-ventricular pressure parameters or flow sizes, respectively. The vector diagrammes result from the momentaneous pressure within the v... | [
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PMID:8881 | [Round table discussion. Ulcer - vagus - gastrin]. | 1. Both gastrin and the vagus nerve play a part in the pathogenesis of the duodenal ulcer. Which of these two factors is of greater significance--this problem is still subject to discussion as is the question whether other factors such as duodenal neutralization are more important than hitherto assumed. 2. At this time... | [Round table discussion. Ulcer - vagus - gastrin]. 1. Both gastrin and the vagus nerve play a part in the pathogenesis of the duodenal ulcer. Which of these two factors is of greater significance--this problem is still subject to discussion as is the question whether other factors such as duodenal neutralization are mo... | [
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PMID:8882 | [Stress ulcer: clinical aspects, pathogenesis, diagnosis and therapy]. | The frequency, the treatment and the mortality of stress induced ulcers and erosions of the upper alimentary tract are surveyed. The experimental data concerning such ulcers and erosions are reported. Most important is the local mucosal ischaemia with a concomitant reabsorption of H-ions. Intravasal coagulation process... | [Stress ulcer: clinical aspects, pathogenesis, diagnosis and therapy]. The frequency, the treatment and the mortality of stress induced ulcers and erosions of the upper alimentary tract are surveyed. The experimental data concerning such ulcers and erosions are reported. Most important is the local mucosal ischaemia wi... | [
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PMID:8883 | [Interaction between gastrointestinal hormones and endocrine regulation]. | The vicinity of several hormone-producing glands as part of the anatomy of the intestinal tract and the resulting interaction has been confirmed by the discovery of hormonal factors of a specifically gastro-intestinal origin. Today we are mainly interested in the interaction between intermediary metabolism and incretor... | [Interaction between gastrointestinal hormones and endocrine regulation]. The vicinity of several hormone-producing glands as part of the anatomy of the intestinal tract and the resulting interaction has been confirmed by the discovery of hormonal factors of a specifically gastro-intestinal origin. Today we are mainly ... | [
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PMID:8884 | [Uterine activity under tocolysis through a beta-sympathomimetic (author's transl)]. | The actual mechanism of tocolytic effect of beta-mimetics is not yet known. While they are able to stop labour, the effect in vitro on myometral filaments is very different. In contrast to this, the socalled Ca++ -antagonists have an excellent relaxing effect on myometrium in vitro, but they are clinically ineffective.... | [Uterine activity under tocolysis through a beta-sympathomimetic (author's transl)]. The actual mechanism of tocolytic effect of beta-mimetics is not yet known. While they are able to stop labour, the effect in vitro on myometral filaments is very different. In contrast to this, the socalled Ca++ -antagonists have an e... | [
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PMID:8885 | [Effect of arterial hypoxia and acidosis on fibrillation threshold in the cat heart in vivo]. | The influence of severe arterial hypoxia and acidosis on the fibrillation threshold was checked in 22 cats. Two groups were formed: in 10 cats (group I) acidosis was produced by 2-N lactic acid infusion; in the second group of 12 animals the respirator was turned off for 60 seconds, thus producing a low arterial PO2. I... | [Effect of arterial hypoxia and acidosis on fibrillation threshold in the cat heart in vivo]. The influence of severe arterial hypoxia and acidosis on the fibrillation threshold was checked in 22 cats. Two groups were formed: in 10 cats (group I) acidosis was produced by 2-N lactic acid infusion; in the second group of... | [
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PMID:8886 | Reversible transformation of precipitated and nonprecipitated lipoproteins recombined from proteins and lipids of erythrocyte membranes. | The sedimentation at low speed centrifugation of a lipoprotein recombined from the lipids and the strongly bound proteins of the human erythrocyte membrane depends on pH: between 4.5 and 6.0, most of the liproprotein sediments, whereas at pH 7.0-8.5, up to 90% remains in the supernatant. Precipitation of the lipoprotei... | Reversible transformation of precipitated and nonprecipitated lipoproteins recombined from proteins and lipids of erythrocyte membranes. The sedimentation at low speed centrifugation of a lipoprotein recombined from the lipids and the strongly bound proteins of the human erythrocyte membrane depends on pH: between 4.5 ... | [
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PMID:8887 | Galactans and anti-galactans from invertebrates. | Antibody-like substances with anti-carbohydrate specificities directed against different structures of galactans have been detected in several invertebrates. | Galactans and anti-galactans from invertebrates. Antibody-like substances with anti-carbohydrate specificities directed against different structures of galactans have been detected in several invertebrates. | [
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PMID:8888 | ["Synthetical" aiptasia mutabilis RAPP (coelenterata) (author's transl)]. | After being cultivated in the dark for some months and after being fed with food free of carotenoids during the time Aiptasia mutabilis (Coelenterata) loses its symbiontic algae (rich in brown fucoxanthin) and becomes transparent white. This disarranged symbiosis may be regenerated under light cultivation by adding dif... | ["Synthetical" aiptasia mutabilis RAPP (coelenterata) (author's transl)]. After being cultivated in the dark for some months and after being fed with food free of carotenoids during the time Aiptasia mutabilis (Coelenterata) loses its symbiontic algae (rich in brown fucoxanthin) and becomes transparent white. This disa... | [
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PMID:8889 | Studies on the undecapeptide of ferricytochrome c using ESR, Mössbauer and visible spectroscopies. | The ESR, Mössbauer, and visible spectra of the undecapeptide of ferricytochrome c (HPp) were measured for both the solid peptide and solutions of the peptide at pH 1.5, 7, and 10. At the low pH, the iron exists in the HPp in the high-spin species. At neutral and alkaline pHs, the low-spin ferric species predominate. Th... | Studies on the undecapeptide of ferricytochrome c using ESR, Mössbauer and visible spectroscopies. The ESR, Mössbauer, and visible spectra of the undecapeptide of ferricytochrome c (HPp) were measured for both the solid peptide and solutions of the peptide at pH 1.5, 7, and 10. At the low pH, the iron exists in the HPp... | [
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PMID:8894 | Studies on Hymenolepis microstoma in vitro. II. Effect of yeast extract on development and maturation. | Four day old in vivo Hymenolepis microstoma were cultured in vitro for 6 days in media containing 2, 1, 0.5 and 0.1% yeast extract. Worms from all groups including control group increased in length and produced nearly equivalent numbers of proglottids. However, worms grown in yeast extract added media produced signific... | Studies on Hymenolepis microstoma in vitro. II. Effect of yeast extract on development and maturation. Four day old in vivo Hymenolepis microstoma were cultured in vitro for 6 days in media containing 2, 1, 0.5 and 0.1% yeast extract. Worms from all groups including control group increased in length and produced nearly... | [
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PMID:8891 | The use of 1-anilino-8-naphthalene sulfonate as fluorescent probe for conformational studies on ribulose-1,5-bisphosphate carboxylase. | The influence of Mg2+ ions and temperature on the structure of the enzyme ribulose-1,5-bisphosphate carboxylase was investigated using the fluorescent probe 1-anilino-8-naphthalene sulfonate (ANS). The binding of ANS to the enzyme molecule caused a significant increase of fluorescence emission which was further enhance... | The use of 1-anilino-8-naphthalene sulfonate as fluorescent probe for conformational studies on ribulose-1,5-bisphosphate carboxylase. The influence of Mg2+ ions and temperature on the structure of the enzyme ribulose-1,5-bisphosphate carboxylase was investigated using the fluorescent probe 1-anilino-8-naphthalene sulf... | [
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PMID:8890 | Physiological effects of sucrose substitutes and artificial sweeteners on growth pattern and acid production of glucose-grown Streptococcus mutans strains in vitro. | The synergistic effects of four sucrose substitutes, polysorbate and five artificial sweeteners were studied in vitro on growth pattern and acid production of seven glucose-grown Streptococcus mutans strains, representing the five serological groups after Bratthall. Four distinct growth patterns during glucose fermenta... | Physiological effects of sucrose substitutes and artificial sweeteners on growth pattern and acid production of glucose-grown Streptococcus mutans strains in vitro. The synergistic effects of four sucrose substitutes, polysorbate and five artificial sweeteners were studied in vitro on growth pattern and acid production... | [
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0.031... |
PMID:8892 | Tautomerism of isoguanosine and solvent-induced keto-enol equilibrium. | Ultraviolet and infrared absorption spectroscopy, in aqueous and non-aqueous media, have been employed to study the tautomerism of 9-substituted isoguanines, including the nucleoside isoguanosine. With the aid of a series of model compounds, it was shown that 9-substituted isoguanines, and isoguanosine, in aqueous medi... | Tautomerism of isoguanosine and solvent-induced keto-enol equilibrium. Ultraviolet and infrared absorption spectroscopy, in aqueous and non-aqueous media, have been employed to study the tautomerism of 9-substituted isoguanines, including the nucleoside isoguanosine. With the aid of a series of model compounds, it was ... | [
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PMID:8893 | Isolation and properties of yeast mutants with highly efficient thymidylate utilization. | A screening procedure is presented which allows the isolation of yeast mutants (typ tir) with highly efficient utilization of exogenous deoxythymidine-5'-monophosphate (5'-dTMP) (greater than 50%). Data are given concerning the phenomenon of 5'-dTMP utilization in general: (i) The ability of S. cerevisiae to incorporat... | Isolation and properties of yeast mutants with highly efficient thymidylate utilization. A screening procedure is presented which allows the isolation of yeast mutants (typ tir) with highly efficient utilization of exogenous deoxythymidine-5'-monophosphate (5'-dTMP) (greater than 50%). Data are given concerning the phe... | [
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PMID:8899 | [Electron microscopic findings in a polyneuropathy complicating panarteritis nodosa]. | Electromicroscopial changes were observed in arterioles, nerves, and striated skeleton muscle cells in a case of clinically and histologically definite polyarteritis nodosa with polyneuropathy. Inflammatory infiltrates were found in and around arteriolar walls; motor nerves were partly demarkated and presynaptic motor ... | [Electron microscopic findings in a polyneuropathy complicating panarteritis nodosa]. Electromicroscopial changes were observed in arterioles, nerves, and striated skeleton muscle cells in a case of clinically and histologically definite polyarteritis nodosa with polyneuropathy. Inflammatory infiltrates were found in a... | [
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PMID:8935 | [Treatment of threatened early abortion (6th-16th week of pregnancy) of Th 1165a (Partusisten)]. | The report is presented about the treatment of the abortus imminens in the early pregnancy between the 6th and 16th weeks with a new tocolytical substance Th 1165a (Partusisten) on the basis of 61 patients. 40 of the patients reached full term delivery (41 new borns). All new borns except one with multiple chromosomal ... | [Treatment of threatened early abortion (6th-16th week of pregnancy) of Th 1165a (Partusisten)]. The report is presented about the treatment of the abortus imminens in the early pregnancy between the 6th and 16th weeks with a new tocolytical substance Th 1165a (Partusisten) on the basis of 61 patients. 40 of the patien... | [
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PMID:8936 | [Effect of the vernix caseosa content in the amniotic fluid on the actual pH-value of the amniotic fluid]. | To determine the eventual influence of the vernix caseosa on the actual pH-value of the amniotic fluid we compared the pH-value of 50 samples of non-filtered amniotic fluid and the pH-values of filtered portions of the same samples. The samples were taken after delivery of the fetus. We found a distinct shift of the p... | [Effect of the vernix caseosa content in the amniotic fluid on the actual pH-value of the amniotic fluid]. To determine the eventual influence of the vernix caseosa on the actual pH-value of the amniotic fluid we compared the pH-value of 50 samples of non-filtered amniotic fluid and the pH-values of filtered portions ... | [
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PMID:8938 | [Serologic properties of strains of Cl. perfringens isolated from the intestinal contents of healthy subjects]. | A study was made of the quantitative content in the intestine of C1. perfringens strains in 6 healthy persons who stayed in a hermetically sealed space for 1 month and for 1 year. C1. perfingens strains were isolated from the fecal samples of each of the volunteers at various periods of the trial. A total of 570 strain... | [Serologic properties of strains of Cl. perfringens isolated from the intestinal contents of healthy subjects]. A study was made of the quantitative content in the intestine of C1. perfringens strains in 6 healthy persons who stayed in a hermetically sealed space for 1 month and for 1 year. C1. perfingens strains were ... | [
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PMID:8940 | [Resistance to levomycetin and activity of several enzymes in Escherichia coli and the agent of plague]. | The authors compared the activity of acetyl-CoA-synthetase and of the enzymes belonging to the group of asparaginic acid in levomycetin sensitive and resistant strains of Y. pestis and E. coli. There were revealed marked differences in the activity of aspartase, fumarase, synthetase and desamidase of L-asparagin, and a... | [Resistance to levomycetin and activity of several enzymes in Escherichia coli and the agent of plague]. The authors compared the activity of acetyl-CoA-synthetase and of the enzymes belonging to the group of asparaginic acid in levomycetin sensitive and resistant strains of Y. pestis and E. coli. There were revealed m... | [
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PMID:8941 | Hypophyso-gonadal function in the cryptorchid child: differences between unilateral and bilateral cryptorchids. | In 22 normal boys, 33 unilateral and 14 bilateral cryptorchids, a gonadal function test (2000 IU of HCG im each day for three days and assays of plasma testosterone and plasma oestradiol-17beta before and after the HCG administration) as well as an LH-RH test were carried out. In 60% of the cases, both normal and crypt... | Hypophyso-gonadal function in the cryptorchid child: differences between unilateral and bilateral cryptorchids. In 22 normal boys, 33 unilateral and 14 bilateral cryptorchids, a gonadal function test (2000 IU of HCG im each day for three days and assays of plasma testosterone and plasma oestradiol-17beta before and aft... | [
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PMID:8942 | Halothane anaesthesia in caesarean section. | The safety and efficacy of halothane anaesthesia were investigated in 97 caesarean sections using 0.4-0.6% halothane added to a mixture of 61 N2O/3-4 1 O2. The administration of halothane was initiated before intubation and terminated immediately prior to delivery. Only one patient reported memories from the operation.... | Halothane anaesthesia in caesarean section. The safety and efficacy of halothane anaesthesia were investigated in 97 caesarean sections using 0.4-0.6% halothane added to a mixture of 61 N2O/3-4 1 O2. The administration of halothane was initiated before intubation and terminated immediately prior to delivery. Only one p... | [
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PMID:8943 | The haemodynamic effects of unsupplemented nitrous oxide-oxygen-relaxant anaesthesia in cardiac patients. | The effect on the systemic and pulmonary circulation of unsupplemented nitrous oxide in about 30% oxygen, with and without IPPV, was investigated in five cardiac patients and compared with control periods at rest with air breathing. The results of this investigation show that nitrous oxide in conventional oxygen concen... | The haemodynamic effects of unsupplemented nitrous oxide-oxygen-relaxant anaesthesia in cardiac patients. The effect on the systemic and pulmonary circulation of unsupplemented nitrous oxide in about 30% oxygen, with and without IPPV, was investigated in five cardiac patients and compared with control periods at rest w... | [
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PMID:8944 | Histochemical studies on the adrenal glands of the marmosets (Callithrix jacchus and Callithrix penicillata). | The histrochemistry of the adrenal glands was studied in four adult male marmosets (two Callithrix jacchus and two Callithrix penicillata). It was impossible to demonstrate any reactivity to UDPG-GT, ADH, alanyl aminopeptidase, leucine aminopeptidase, xilitol (NAD-dependent) dehydrogenase, beta-glucuronidase and aryl-s... | Histochemical studies on the adrenal glands of the marmosets (Callithrix jacchus and Callithrix penicillata). The histrochemistry of the adrenal glands was studied in four adult male marmosets (two Callithrix jacchus and two Callithrix penicillata). It was impossible to demonstrate any reactivity to UDPG-GT, ADH, alany... | [
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PMID:8945 | Alkaline phosphatase activity in the human tonsils and its relation to tonsillar diseases. | Alkaline phosphatase activity was examined in the human tonsils in fetal life and after repeated attacks of acute tonsillitis and in quinsy. Gomori's metal precipitate technique was used to demonstrate the phosphatase activity using four different substrates: sodium beta-glycerophosphate and adenosine triphosphate at p... | Alkaline phosphatase activity in the human tonsils and its relation to tonsillar diseases. Alkaline phosphatase activity was examined in the human tonsils in fetal life and after repeated attacks of acute tonsillitis and in quinsy. Gomori's metal precipitate technique was used to demonstrate the phosphatase activity us... | [
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PMID:8946 | Amperometric and polarographic study of the SH-activity of MEPRIN (alpha-mercapto-propionylglycine). | The SH-groups of alpha-mercapto-propionylglycine (MEPRIN) are remarkably stable in diluted solution either at room temperature or at 50 degrees C, even if storing takes place under air-bubbling. The SH-activity was measured by polarographic method and amperometric titration. Neutralization of the carboxyl group decreas... | Amperometric and polarographic study of the SH-activity of MEPRIN (alpha-mercapto-propionylglycine). The SH-groups of alpha-mercapto-propionylglycine (MEPRIN) are remarkably stable in diluted solution either at room temperature or at 50 degrees C, even if storing takes place under air-bubbling. The SH-activity was meas... | [
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PMID:8948 | Effects of phospholine iodide on the metabolites of the glycolytic, pentose phosphate and sorbitol pathways in the rabbit lens. | Steady-state concentrations of the key intermediates from the glycolytic, pentose phosphate, and sorbitol pathways as well as the pyridine nucleotides were measured from the lens after 0.25% phospholine iodide had been instilled into rabbits' eyes twice a day for 18 weeks. In the lenses of those rabbits which had recei... | Effects of phospholine iodide on the metabolites of the glycolytic, pentose phosphate and sorbitol pathways in the rabbit lens. Steady-state concentrations of the key intermediates from the glycolytic, pentose phosphate, and sorbitol pathways as well as the pyridine nucleotides were measured from the lens after 0.25% p... | [
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PMID:8949 | Clinical and cytogenetic studies in undescended testes. | 168 boys and 2.5-16.8 years with unilateral or bilateral undescended testes or anorchia were studied. Retention was severe (canalicular or intraabdominal) in 1/4 and moderate in 3/4 of the cases. In unilateral retention, the volume of the scrotal testis was usually normal throughout childhood whereas pubertal testicula... | Clinical and cytogenetic studies in undescended testes. 168 boys and 2.5-16.8 years with unilateral or bilateral undescended testes or anorchia were studied. Retention was severe (canalicular or intraabdominal) in 1/4 and moderate in 3/4 of the cases. In unilateral retention, the volume of the scrotal testis was usuall... | [
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PMID:8950 | Endocrinological studies in undescended testes. | A cross-sectional study was carried out on 168 boys aged 2.5-16.8 years with unilateral or bilateral testicular maldescent. Urinary excretion of testosterone, delta4-androstenedione, LH and FSH was investigated. The results were related to chronological age, bone age and sexual maturation stage. Urinary testosterone ex... | Endocrinological studies in undescended testes. A cross-sectional study was carried out on 168 boys aged 2.5-16.8 years with unilateral or bilateral testicular maldescent. Urinary excretion of testosterone, delta4-androstenedione, LH and FSH was investigated. The results were related to chronological age, bone age and ... | [
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PMID:8951 | Allo-aggression in chickens. II. Cellular expression of the AA gene products. | B1-anti-B2 and B2-anti-B1 allo-antisera were raised by i.v. immunization of homozygous B1/1 and B2/2 chickens, respectively, with B1/2 cells of the following sources: peripheral blood leucocytes (PBL), erythrocytes, thymus cells and bursa cells. Purified suspensions of these all produced anti-B allo-antibodies which co... | Allo-aggression in chickens. II. Cellular expression of the AA gene products. B1-anti-B2 and B2-anti-B1 allo-antisera were raised by i.v. immunization of homozygous B1/1 and B2/2 chickens, respectively, with B1/2 cells of the following sources: peripheral blood leucocytes (PBL), erythrocytes, thymus cells and bursa cel... | [
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PMID:8947 | [Epileptic headaches (author's transl)]. | The author describes three observations characterized by the following similar features: 1. Children, between 2 and 9 years, suffering from attacks of sterotyped headaches. 2. EEG with bursts of high- voltage paroxysmal discharges, mainly during hyperventilation. 3. Efficiency of antiepileptic drugs contrary to antimig... | [Epileptic headaches (author's transl)]. The author describes three observations characterized by the following similar features: 1. Children, between 2 and 9 years, suffering from attacks of sterotyped headaches. 2. EEG with bursts of high- voltage paroxysmal discharges, mainly during hyperventilation. 3. Efficiency o... | [
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PMID:8955 | Influence of pH and pCO2 on alpha-receptor mediated contraction in brain vessels. | The response of isolated brain vessels to various pH levels or carbon dioxide tensions was analyzed. Reduction of the pH induced a slight relaxation of the vessel, whereas an increase in the pH produced a slight contraction. These effects were markedly exaggerated when the alpha-adrenergic receptors in the vascular wal... | Influence of pH and pCO2 on alpha-receptor mediated contraction in brain vessels. The response of isolated brain vessels to various pH levels or carbon dioxide tensions was analyzed. Reduction of the pH induced a slight relaxation of the vessel, whereas an increase in the pH produced a slight contraction. These effects... | [
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PMID:8956 | [Logical analysis of the respective influence of 3 experimental variables using a diagram by L. Carroll. Application of this method to a clinical trial of 2 forms of Noveril]. | The analysis of the results gathered in a double-blind randomized cross-over clinical trial of dibenzepine was systematized in order to evidence the relation existing between the experimental variables and the effects measured. The suggested method of analysis is based on logic and makes profit of a diagram by Carroll.... | [Logical analysis of the respective influence of 3 experimental variables using a diagram by L. Carroll. Application of this method to a clinical trial of 2 forms of Noveril]. The analysis of the results gathered in a double-blind randomized cross-over clinical trial of dibenzepine was systematized in order to evidence... | [
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PMID:8958 | Effects of chlorthalidone on serum and total body potassium in hypertensive patients. | Total body potassium has been estimated in 26 hypertensive patients who were hypokalaemic as a result of long-term chlorthalidone treatment (mean 20.5 months), while they were on chlorthalidone and 4 weeks after this had been discontinued. The mean difference amounted to only 95 mEq (not significant). In 6 additional p... | Effects of chlorthalidone on serum and total body potassium in hypertensive patients. Total body potassium has been estimated in 26 hypertensive patients who were hypokalaemic as a result of long-term chlorthalidone treatment (mean 20.5 months), while they were on chlorthalidone and 4 weeks after this had been disconti... | [
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PMID:8959 | Liver enzymes in alcohol-discordant twins. | Seventy moderately alcohol-discordant male twin pairs have been investigated with respect to some liver enzymes. No differences were found as regards S-ALAT, while significantly higher enzyme levels were demonstrated for S-ASAT, S-ALP and S-GT among the high alcohol consumers compared to their low consuming co-twins. E... | Liver enzymes in alcohol-discordant twins. Seventy moderately alcohol-discordant male twin pairs have been investigated with respect to some liver enzymes. No differences were found as regards S-ALAT, while significantly higher enzyme levels were demonstrated for S-ASAT, S-ALP and S-GT among the high alcohol consumers ... | [
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PMID:8957 | [Ulcerative rectocolitis. Somatic aspects (author's transl)]. | Regional enteritis (Crohn's disease) and ulcerative rectocolitis, both "non specific inflammatory diseases of the bowel", might be diseases with a common etiology but with clinical features corresponding to a different tissular response to a noxious factor. Both diseases are however characterized by distinct clinical, ... | [Ulcerative rectocolitis. Somatic aspects (author's transl)]. Regional enteritis (Crohn's disease) and ulcerative rectocolitis, both "non specific inflammatory diseases of the bowel", might be diseases with a common etiology but with clinical features corresponding to a different tissular response to a noxious factor. ... | [
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PMID:8960 | On the nature of brain stem disorders in severe head injured patients. II. A study on caloric vestibular reactions and neurotransmitter treatment. | The results of electro-oculographic recordings made after caloric vestibular stimulation (C.O.G.) in severe head injured patients are discussed. It was found that: 1. The C.O.G. correlates with the state of consciousness of the patients. 2. The rate of improvement of the C.O.G. correlates with the rate of the clinical ... | On the nature of brain stem disorders in severe head injured patients. II. A study on caloric vestibular reactions and neurotransmitter treatment. The results of electro-oculographic recordings made after caloric vestibular stimulation (C.O.G.) in severe head injured patients are discussed. It was found that: 1. The C.... | [
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PMID:8961 | Adrenergic blockade in subarachnoid haemorrhage. | Over the last 15 years progressive interest has developed in the relationship between subarachnoid haemorrhage, sympathetic nervous system over-activity and the genesis of cerebral artery spasm. Following on from earlier work, vide infra, suggesting that adrenergic blockade might influence the course and prognosis of p... | Adrenergic blockade in subarachnoid haemorrhage. Over the last 15 years progressive interest has developed in the relationship between subarachnoid haemorrhage, sympathetic nervous system over-activity and the genesis of cerebral artery spasm. Following on from earlier work, vide infra, suggesting that adrenergic block... | [
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PMID:8964 | Comparison of function of the distal base between myoglobin and peroxidase. | The heme-linked protonation of a ferrous horseradish peroxidase is assigned to a distal amino acid residue. The conclusion is drawn from analyses of reactions that involve the protonation. Unfortunately it is difficult to apply it to the myoglobin case because no reaction has been found which is coupled with the proton... | Comparison of function of the distal base between myoglobin and peroxidase. The heme-linked protonation of a ferrous horseradish peroxidase is assigned to a distal amino acid residue. The conclusion is drawn from analyses of reactions that involve the protonation. Unfortunately it is difficult to apply it to the myoglo... | [
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PMID:8969 | Biological effects of cyclosporin A: a new antilymphocytic agent. | The fungus metabolite cyclosporin A is a small peptide acting as a novel antilymphocytic agent. It strongly depressed appearance of both direct and indirect plaque-forming cells and produced a clear dose-dependent inhibition of haemagglutinin formation in mice upon oral administration. Skin graft rejection in mice and ... | Biological effects of cyclosporin A: a new antilymphocytic agent. The fungus metabolite cyclosporin A is a small peptide acting as a novel antilymphocytic agent. It strongly depressed appearance of both direct and indirect plaque-forming cells and produced a clear dose-dependent inhibition of haemagglutinin formation i... | [
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PMID:8972 | Ultrastructural comparison of the midgut epithelia of fleas with different feeding behavior patterns (Xenopsylla cheopis, Echidnophaga gallinacea, Tunga penetrans, Siphonaptera, Pulicidae). | This morphological study describes the ultrastructure of the midgut of three flea species, including temporary parasitic fleas (both sexes of Xenopsylla cheopis, males and immature females of Echidnophaga gallinacea and Tunga penetrans) and stationary parasitic fleas (mature females of E. gallinacea and T. penetrans). ... | Ultrastructural comparison of the midgut epithelia of fleas with different feeding behavior patterns (Xenopsylla cheopis, Echidnophaga gallinacea, Tunga penetrans, Siphonaptera, Pulicidae). This morphological study describes the ultrastructure of the midgut of three flea species, including temporary parasitic fleas (bo... | [
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PMID:8973 | Nutrition of Glossina morsitans: metabolism of U-14C threonine during pregnancy. | Following injection of U-14C threonine into the haemolymph of adult female Glossina morsitans during late pregnancy, radioactivity was detected in the postparturient female and in its offspring, in threonine, lipids, and a range of non-essential amino acids. The level of radioactivity recovered from the larva was highe... | Nutrition of Glossina morsitans: metabolism of U-14C threonine during pregnancy. Following injection of U-14C threonine into the haemolymph of adult female Glossina morsitans during late pregnancy, radioactivity was detected in the postparturient female and in its offspring, in threonine, lipids, and a range of non-ess... | [
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PMID:8974 | Development of Trypanosoma (Trypanozoon) brucei in Glossina morsitans inoculated into the tsetse haemocoel. | Classically, infective development of Trypanosoma (Trypanozoon) brucei in tsetse flies is thought to take the route crop-midgut-hindgut proventriculus-hypopharynx-salivary gland, where the parasites reach their infective phase. It has been shown experimentally that T. (T.) brucei is capable of developing up to the infe... | Development of Trypanosoma (Trypanozoon) brucei in Glossina morsitans inoculated into the tsetse haemocoel. Classically, infective development of Trypanosoma (Trypanozoon) brucei in tsetse flies is thought to take the route crop-midgut-hindgut proventriculus-hypopharynx-salivary gland, where the parasites reach their i... | [
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PMID:8975 | Filaments of Trypanosoma brucei: some notes on differences in origin and structure in two strains of Trypanosoma (Trypanozoon) brucei rhodesiense. | Filaments attached to trypanosomes of two strains of T. (T.) brucei were studied by electron microscopy and two distinct types identified: short-thick and long-thin. The former are associated with stumpy trypanosomes and are secretions, via the flagellar pocket, which originate in the area of the Golgi complex, during ... | Filaments of Trypanosoma brucei: some notes on differences in origin and structure in two strains of Trypanosoma (Trypanozoon) brucei rhodesiense. Filaments attached to trypanosomes of two strains of T. (T.) brucei were studied by electron microscopy and two distinct types identified: short-thick and long-thin. The for... | [
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PMID:8976 | [New species of Microsporidia, parasite of Myriapoda-Diplopoda of South Dahomey]. | A new microsporidian parasitic in Myriapoda-Diplopoda of Sud-Dahomey (Habrodesmus falx Cook & Oxydesmus granulosus Palisot de Beauvois) is described by photonic microscopy. It can be recognized by its thick-enveloped pansporoblasts yielding from 30 to 66 elongate and ovoid spores measuring 4,8 mum in length and 2,2... | [New species of Microsporidia, parasite of Myriapoda-Diplopoda of South Dahomey]. A new microsporidian parasitic in Myriapoda-Diplopoda of Sud-Dahomey (Habrodesmus falx Cook & Oxydesmus granulosus Palisot de Beauvois) is described by photonic microscopy. It can be recognized by its thick-enveloped pansporoblasts yi... | [
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PMID:8977 | [General survey of the present distribution of helminths in Iran and comparison with those of past years]. | In this paper the literature on helminthiasis in Iran is reviewed and the distribution, prevalence and intensity of infections caused by helminths are discussed. A comparison of prevalence and intensity of infections was accomplished in the recent 10 years by the author. Hookworm infections are found mostly in the nort... | [General survey of the present distribution of helminths in Iran and comparison with those of past years]. In this paper the literature on helminthiasis in Iran is reviewed and the distribution, prevalence and intensity of infections caused by helminths are discussed. A comparison of prevalence and intensity of infecti... | [
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PMID:8980 | Otitis media of infancy and early childhood. A double-blind study of four treatment regimens. | A double-blind, randomized trial of four antimicrobial regimens was conducted in 383 infants and children with acute otitis media. The drugs used were penicillin V, amoxicillin trihydrate, erythromycin estolate, and erythromycin estolate with trisulfapyrimidines. Aspiration of middle ear fluid for culture was done befo... | Otitis media of infancy and early childhood. A double-blind study of four treatment regimens. A double-blind, randomized trial of four antimicrobial regimens was conducted in 383 infants and children with acute otitis media. The drugs used were penicillin V, amoxicillin trihydrate, erythromycin estolate, and erythromyc... | [
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PMID:8985 | Influences on role expansion. | Several factors are influencing role expansion for registered nurses, among them the shortage of primary care physicians, the federal government, the physician's assistant movement, the growing complexity of acute hospital care, educational reform, and the women's liberation movement. As state licensure statutes are re... | Influences on role expansion. Several factors are influencing role expansion for registered nurses, among them the shortage of primary care physicians, the federal government, the physician's assistant movement, the growing complexity of acute hospital care, educational reform, and the women's liberation movement. As s... | [
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PMID:8986 | Maternal and fetal effects of lumbar epidural analgesia for labor and delivery in patients with gestational hypertension. | The effects of continuous lumbar epidural analgesia for labor and delivery were studied in 20 women with gestational hypertension. Maternal hemodynamics, renal function, acid-base, and blood gas findings were examined together with newborn APgar scores and umbilical vessel blood gas and acid-base values. Minimal change... | Maternal and fetal effects of lumbar epidural analgesia for labor and delivery in patients with gestational hypertension. The effects of continuous lumbar epidural analgesia for labor and delivery were studied in 20 women with gestational hypertension. Maternal hemodynamics, renal function, acid-base, and blood gas fin... | [
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PMID:8987 | Circulatory response to atropine in sheep fetus. | Atropine was given to the semichronic sheep fetus intravenously. Fetal heart rate, fetal perfusion pressure, and carotid blood flow increased. Cerebral blood flow was measured with the radioactive microsphere technique. Atropine was capable of increasing the cerebral blood flow. Elevation of carbon dioxide also caused ... | Circulatory response to atropine in sheep fetus. Atropine was given to the semichronic sheep fetus intravenously. Fetal heart rate, fetal perfusion pressure, and carotid blood flow increased. Cerebral blood flow was measured with the radioactive microsphere technique. Atropine was capable of increasing the cerebral blo... | [
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PMID:8988 | Nutritional deficiency, immunologic function, and disease. | Several experiments conducted by our group over a period of 6 years have shown that nutritional stress, especially protein and/or calorie deprivation, leads to many, often dramatic, changes in the immune responses of mice, rats, and guinea pigs. Chronic protein deprivation (CPD) has been shown to create an enhancing ef... | Nutritional deficiency, immunologic function, and disease. Several experiments conducted by our group over a period of 6 years have shown that nutritional stress, especially protein and/or calorie deprivation, leads to many, often dramatic, changes in the immune responses of mice, rats, and guinea pigs. Chronic protein... | [
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PMID:8989 | Acid-base changes in milk and blood of rats in acidosis and alkalosis. | Lactating white rats (Rattus norvegicus) were subjected to metabolic and respiratory acidosis and metabolic alkalosis. Before and during the various treatments, the acid-base status of heart blood and milk was determined. Acute metabolic acidosis lowered the pH of plasma and milk; Pco(2) and bicarbonate concentrations ... | Acid-base changes in milk and blood of rats in acidosis and alkalosis. Lactating white rats (Rattus norvegicus) were subjected to metabolic and respiratory acidosis and metabolic alkalosis. Before and during the various treatments, the acid-base status of heart blood and milk was determined. Acute metabolic acidosis lo... | [
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PMID:8990 | Role of oxalacetate in lipoate effect on frog gastric mucosa. | The mechanism of action of lipoate on frog gastric mucosa was investigated. Oxalacetate (OAA) reversed lipoate-inhibited QO2 and QH+ of chambered mucosas by 70 and 40%, respectively. Pyruvate or glucose produced similar effects. Neither activity was affected by OAA when added after glucose, pyruvate, decanoate, butyrat... | Role of oxalacetate in lipoate effect on frog gastric mucosa. The mechanism of action of lipoate on frog gastric mucosa was investigated. Oxalacetate (OAA) reversed lipoate-inhibited QO2 and QH+ of chambered mucosas by 70 and 40%, respectively. Pyruvate or glucose produced similar effects. Neither activity was affected... | [
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PMID:8991 | Sensitivity of small subcutaneous vessels to altered respiratory gases and local pH. | Television microscopy was used to quantitate the responses of small arteries and veins, in the wings of unanesthetized bats, to alterations in the inspired concentrations of O2 and CO2. Mean arterial pressure, heart rate, and the diameters of small arteries (28-54 mum) and veins (50-128 mum) were measured during a 90-m... | Sensitivity of small subcutaneous vessels to altered respiratory gases and local pH. Television microscopy was used to quantitate the responses of small arteries and veins, in the wings of unanesthetized bats, to alterations in the inspired concentrations of O2 and CO2. Mean arterial pressure, heart rate, and the diame... | [
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PMID:8992 | Hypothalamic and thalamic blood flow during somatic afferent stimulation in dogs. | The effect of somatic afferent C fiber stimulation on regional cerebral blood flow (rCBF) and cerebral tissue available oxygen (aO2) was studied in 20 dogs under chloralose anesthesia. Mean arterial blood pressure, arterial Pco2, and pH were stabilized before and during the 3-min stimulation of the sciatic nerves (20 V... | Hypothalamic and thalamic blood flow during somatic afferent stimulation in dogs. The effect of somatic afferent C fiber stimulation on regional cerebral blood flow (rCBF) and cerebral tissue available oxygen (aO2) was studied in 20 dogs under chloralose anesthesia. Mean arterial blood pressure, arterial Pco2, and pH w... | [
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PMID:8993 | Interorgan transport of amino acids in hemorrhagic shock. | Arterial concentrations and net organ metabolism of amino acids (AA), O2, CO2, H+, and glucose (Glc) were measured in two dogs before and during hemorrhage and after blood replacement. Shock caused increased splanchnic and decreased peripheral blood flow and O2 consumption. Po2 decreased more in hepatic venous than in ... | Interorgan transport of amino acids in hemorrhagic shock. Arterial concentrations and net organ metabolism of amino acids (AA), O2, CO2, H+, and glucose (Glc) were measured in two dogs before and during hemorrhage and after blood replacement. Shock caused increased splanchnic and decreased peripheral blood flow and O2 ... | [
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PMID:8994 | Effect of the histamine (H2) inhibitor metiamide on histamine-stimulated bile flow in dogs. | The effects of the histamine H2-receptor inhibitor metiamide on histamine-stimulated canine bile flow and gastric hydrogen ion output were evaluated. Histamine was found to stimulate bile volume in doses comparable to those that stimulated gastric hydrogen ion output; both responses appeared to have the same maximal re... | Effect of the histamine (H2) inhibitor metiamide on histamine-stimulated bile flow in dogs. The effects of the histamine H2-receptor inhibitor metiamide on histamine-stimulated canine bile flow and gastric hydrogen ion output were evaluated. Histamine was found to stimulate bile volume in doses comparable to those that... | [
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PMID:8995 | Sympathetic nervous system and renin release from submaxillary glands in vitro. | We previously reported that alpha- but not beta-adrenergic agonists stimulate renin release from mouse submaxillary glands in vivo. The present studies were undertaken to determine if these in vivo effects were due to a direct action on the submaxillary glands and to find out if cyclic AMP (cAMP) might be involved in s... | Sympathetic nervous system and renin release from submaxillary glands in vitro. We previously reported that alpha- but not beta-adrenergic agonists stimulate renin release from mouse submaxillary glands in vivo. The present studies were undertaken to determine if these in vivo effects were due to a direct action on the... | [
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PMID:8996 | H+ current response to CO2 and carbonic anhydrase inhibition in turtle bladder. | To evaluate the role of CO2 and carbonic anhydrase (CA) in H+ transport (JH) by turtle urinary bladder the effect of CO2 addition, with and without addition of CA inhibitiors, was examined on JH. Since in the presence of exogenous CO2 and HCO3- the pH stat-measured rate of mucosal (M) acidification underestimates JH by... | H+ current response to CO2 and carbonic anhydrase inhibition in turtle bladder. To evaluate the role of CO2 and carbonic anhydrase (CA) in H+ transport (JH) by turtle urinary bladder the effect of CO2 addition, with and without addition of CA inhibitiors, was examined on JH. Since in the presence of exogenous CO2 and H... | [
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PMID:8997 | Effect of potassium depletion on cerebrospinal fluid bicarbonate homeostasis. | We have examined the effect of K depletion on CSF [HCO3-] homeostasis in awake rats. The relationship of CSF [HCO3-] to arterial [HCO3-] in metabolic acid-base disturbances is displaced is an upward direction and has a significantly increased slope in K-depleted vs. control rats (0.51 +/- 0.02 vs. 0.42 +/- 0.02). Resul... | Effect of potassium depletion on cerebrospinal fluid bicarbonate homeostasis. We have examined the effect of K depletion on CSF [HCO3-] homeostasis in awake rats. The relationship of CSF [HCO3-] to arterial [HCO3-] in metabolic acid-base disturbances is displaced is an upward direction and has a significantly increased... | [
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PMID:8998 | Rational treatment for an irrational disorder: what does the schizophrenic patient need? | The author discusses the results of a review of controlled studies of treatment approaches to schizophrenia. Although the research evidence strongly supports the efficacy of pharmacotherapy, this finding should not be interpreted as meaning that all schizophrenic patients should receive antipsychotic drugs or that othe... | Rational treatment for an irrational disorder: what does the schizophrenic patient need? The author discusses the results of a review of controlled studies of treatment approaches to schizophrenia. Although the research evidence strongly supports the efficacy of pharmacotherapy, this finding should not be interpreted a... | [
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PMID:8999 | Infective larvae of Brugia: escape from mosquitoes into water and subsequent oral infectivity in jirds. | Published work showed that third-stage larvae (L-3s) escape into water from dead or dying, Brugia pahangi-infected, Aedes aegypti. The present study revealed the same escape phenomenon among B. pahangi-infected Armigeres subalbatus, Anopheles quadrimaculatus, and Aedes togoi, and among Brugia malayi-infected Ae. aegypt... | Infective larvae of Brugia: escape from mosquitoes into water and subsequent oral infectivity in jirds. Published work showed that third-stage larvae (L-3s) escape into water from dead or dying, Brugia pahangi-infected, Aedes aegypti. The present study revealed the same escape phenomenon among B. pahangi-infected Armig... | [
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PMID:9000 | Experimental studies on the transmission of hepatitis B by mosquitoes. | Culex tarsalis and Aedes aegypti mosquitoes were fed on chimpanzees carrying hepatitis B surface antigen (HBS Ag) of known infectivity and pools were tested by radioimmunoassay daily for the presence of HBS Ag. HBS Ag continued to be detected at low levels in mosquito tissue after digestion of the blood meal. Inoculati... | Experimental studies on the transmission of hepatitis B by mosquitoes. Culex tarsalis and Aedes aegypti mosquitoes were fed on chimpanzees carrying hepatitis B surface antigen (HBS Ag) of known infectivity and pools were tested by radioimmunoassay daily for the presence of HBS Ag. HBS Ag continued to be detected at low... | [
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PMID:9001 | Plasma activities of lysosomal enzymes after hepatic dearterialization in man. | Six patients with liver metastases from carcinoid or colon carcinoma underwent hepatic derterialization. This operation, known to cause both tumor necrosis and liver cell damage, caused considerable increases of several lysosomal acid hydrolases in the circulation. Thus, beta-glucosidase showed a small temporary increa... | Plasma activities of lysosomal enzymes after hepatic dearterialization in man. Six patients with liver metastases from carcinoid or colon carcinoma underwent hepatic derterialization. This operation, known to cause both tumor necrosis and liver cell damage, caused considerable increases of several lysosomal acid hydrol... | [
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PMID:9005 | [Combined acupuncture analgesia and controlled respiration. A new modified method of anesthesia in open heart surgery (author's transl)]. | From October 1973 to May 1975 cardiae surgery with extracorporal circulation using Acupuncture as Analgesia was performed in 131 patients in the surgical clinic of the University of Giessen. Acupuncture is performed by electric-stimulation of 8 points at the lower legs, the neck and ears with 90 V and 5--6 Htz. All pat... | [Combined acupuncture analgesia and controlled respiration. A new modified method of anesthesia in open heart surgery (author's transl)]. From October 1973 to May 1975 cardiae surgery with extracorporal circulation using Acupuncture as Analgesia was performed in 131 patients in the surgical clinic of the University of ... | [
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PMID:9019 | On the morphology of the human Sertoli cells under normal conditions and in patients with impaired fertility. | Sertoli cells in testicular biopsies from 7 patients with Sertoli-cell only syndrome, 8 patients who had been treated with cyclophosphamide for testicular neoplasia, 8 patients with oligozoospermia, 7 patients with cryptorchidism, and 8 patients with seminoma were examined under the electron microscope and compared wit... | On the morphology of the human Sertoli cells under normal conditions and in patients with impaired fertility. Sertoli cells in testicular biopsies from 7 patients with Sertoli-cell only syndrome, 8 patients who had been treated with cyclophosphamide for testicular neoplasia, 8 patients with oligozoospermia, 7 patients ... | [
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PMID:9020 | Interaction of anesthesia, beta-receptor blockade, and blood loss in dogs with induced myocardial infarction. | The cardiovascular effects of halothane-nitrous oxide anesthesia, and beta-receptor blockade with either propranolol or practolol, were studied in 15 dogs in which severe myocardial infarction had been induced ten days earlier. The hemodynamic responses to blood loss amounting to 25 per cent of estimated blood volume, ... | Interaction of anesthesia, beta-receptor blockade, and blood loss in dogs with induced myocardial infarction. The cardiovascular effects of halothane-nitrous oxide anesthesia, and beta-receptor blockade with either propranolol or practolol, were studied in 15 dogs in which severe myocardial infarction had been induced ... | [
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