id stringlengths 7 10 | title stringlengths 8 354 | content stringlengths 91 4.1k | contents stringlengths 164 4.24k | embedding listlengths 384 384 |
|---|---|---|---|---|
PMID:12375 | Osteomyelitis following puncture wounds of the foot in children. | Review of the laboratory and clinical findings and treatment of eight patients with osteomyelitis of the foot after puncture wounds revealed that: 1) osteomyelitis after puncture wounds is a infrequent but potentially serious complication, with significant morbidity; 2) osteomyelitis is frequently preceded by inadequat... | Osteomyelitis following puncture wounds of the foot in children. Review of the laboratory and clinical findings and treatment of eight patients with osteomyelitis of the foot after puncture wounds revealed that: 1) osteomyelitis after puncture wounds is a infrequent but potentially serious complication, with significan... | [
0.0201619490981102,
-0.01490019727498293,
0.0237608402967453,
-0.014672117307782173,
0.01728362962603569,
-0.021893197670578957,
0.005836276337504387,
0.11762773245573044,
-0.049667876213788986,
0.015322721563279629,
0.035254646092653275,
-0.030415557324886322,
0.04852231964468956,
0.01930... |
PMID:12376 | Ureteral changes in polyarteritis nodosa as seen during excretory urography. | The conventional excretory urogram may provide valuable information in the diagnosis of polyarteritis nodosa. A finding of imprints on the ureteral wall or a nodular appearance of the ureter simulating a string of pearls would seem to be pathognomonic for this disorder. Two cases with these manifestations are presented... | Ureteral changes in polyarteritis nodosa as seen during excretory urography. The conventional excretory urogram may provide valuable information in the diagnosis of polyarteritis nodosa. A finding of imprints on the ureteral wall or a nodular appearance of the ureter simulating a string of pearls would seem to be patho... | [
0.0028841423336416483,
-0.027586504817008972,
0.06657588481903076,
0.00006408962508430704,
0.013621971942484379,
-0.014651586301624775,
0.03962836414575577,
0.03767935186624527,
-0.03479108214378357,
-0.0052030570805072784,
0.03524690121412277,
-0.056303877383470535,
0.007350241765379906,
... |
PMID:12377 | The incidence of intersexuality in patients with hypospadias and cryptorchidism. | The incidence of intersexuality was determined in 45 patients with cryptorchidism and hypospadias seen between 1952 and 1975. Including patients with ambiguous genitalia the incidence was 53 per cent. When patients with ambiguous genitalia were excluded, providing a group more representative of the patient population u... | The incidence of intersexuality in patients with hypospadias and cryptorchidism. The incidence of intersexuality was determined in 45 patients with cryptorchidism and hypospadias seen between 1952 and 1975. Including patients with ambiguous genitalia the incidence was 53 per cent. When patients with ambiguous genitalia... | [
0.0684715062379837,
0.023679053410887718,
0.024978242814540863,
-0.005030068103224039,
-0.052520863711833954,
0.022367604076862335,
0.029136789962649345,
0.04894695803523064,
0.03772345930337906,
0.00014748972898814827,
0.023089777678251266,
-0.03166483715176582,
0.06100976839661598,
0.003... |
PMID:12378 | Calcium oxalate crystalluria. | Calcium oxalate crystals were obtained from urine specimens submitted to a hospital laboratory. The incidence of crystalluria was 4.2 per cent of 42 times the maximum reported incidence of urinary calculi. In our opinion the crystalluria was real and not artifactual. The crystalline structure was determined by polarize... | Calcium oxalate crystalluria. Calcium oxalate crystals were obtained from urine specimens submitted to a hospital laboratory. The incidence of crystalluria was 4.2 per cent of 42 times the maximum reported incidence of urinary calculi. In our opinion the crystalluria was real and not artifactual. The crystalline struct... | [
-0.001762964529916644,
-0.02239207550883293,
0.0382540188729763,
0.035118699073791504,
-0.04093850404024124,
-0.019894178956747055,
0.04109390079975128,
0.04347533360123634,
-0.006868742872029543,
-0.0015551509568467736,
-0.0040895771235227585,
-0.08812825381755829,
-0.005666551645845175,
... |
PMID:12379 | Congenital megalourethra associated with prune belly syndrome. | Dilation of the penile urethra is described in a male infant with the classic triad of the prune belly syndrome. This dilated penile urethra was not accompanied by obstruction of the urethra proximal or distal to the dilation. Dilation of the penile urethra is a rare feature of the prune belly syndrome and may be part ... | Congenital megalourethra associated with prune belly syndrome. Dilation of the penile urethra is described in a male infant with the classic triad of the prune belly syndrome. This dilated penile urethra was not accompanied by obstruction of the urethra proximal or distal to the dilation. Dilation of the penile urethra... | [
0.023922430351376534,
0.02046387456357479,
-0.02146437205374241,
0.07126331329345703,
0.00621308758854866,
-0.011100745759904385,
0.03221151977777481,
0.024628013372421265,
0.01631079986691475,
0.05925881862640381,
0.006226208992302418,
-0.1009235680103302,
0.05842788517475128,
0.003404537... |
PMID:12380 | Chromosomal studies in cryptorchidism. | The chromosomes of undescended tests from 13 boys were analyzed. In 12 of these patients the peripheral blood chromosomes were examined and in 7 the chromosomes of normal skin cultures were examined. In addition to standard techniques the chromosomes also were analyzed by G and Q-banding methods. We were unable to dete... | Chromosomal studies in cryptorchidism. The chromosomes of undescended tests from 13 boys were analyzed. In 12 of these patients the peripheral blood chromosomes were examined and in 7 the chromosomes of normal skin cultures were examined. In addition to standard techniques the chromosomes also were analyzed by G and Q-... | [
-0.007941704243421555,
-0.0021451462525874376,
0.020155062898993492,
0.025775766000151634,
0.04439667612314224,
0.02163871005177498,
-0.029255159199237823,
0.012947501614689827,
-0.038561467081308365,
-0.0007867705426178873,
0.026393646374344826,
-0.04361523687839508,
0.043611135333776474,
... |
PMID:12381 | The staged orchiopexy: a critical review of the literature. | During the last 20 years reports have appeared describing successful results with a 2-stage orchiopexy for patients noted to have a short testicular artery on first exploration. A critical review of these reports indicates that accurate documentation of the phenomenon of spontaneously increasing spermatic cord length f... | The staged orchiopexy: a critical review of the literature. During the last 20 years reports have appeared describing successful results with a 2-stage orchiopexy for patients noted to have a short testicular artery on first exploration. A critical review of these reports indicates that accurate documentation of the ph... | [
-0.0064474972896277905,
0.006181844975799322,
0.033551983535289764,
-0.009833103977143764,
-0.04871649667620659,
0.05545252189040184,
-0.023466523736715317,
0.06833197176456451,
-0.017413737252354622,
-0.017851635813713074,
0.08088372647762299,
-0.016866229474544525,
-0.007996054366230965,
... |
PMID:12383 | Failure to prove arenavirus infection among the small mammals from an endemic area of Korean hemorrhagic nephrosonephritis. | In the light of recent knowledge on a complex of diseases caused by a new group of viruses, arenaviruses, virological studies largely directed toward small field mammals were undertaken during 1973-1974 aiming at etiological clarification of Korean hemorrhagic nephrosonephritis (KHNN). Specimens were collected in an en... | Failure to prove arenavirus infection among the small mammals from an endemic area of Korean hemorrhagic nephrosonephritis. In the light of recent knowledge on a complex of diseases caused by a new group of viruses, arenaviruses, virological studies largely directed toward small field mammals were undertaken during 197... | [
-0.019930968061089516,
0.013790138065814972,
0.027286002412438393,
0.027606766670942307,
0.05023716390132904,
-0.03327696770429611,
0.0522000752389431,
0.0546455942094326,
-0.03202543780207634,
0.010048521682620049,
0.0317792110145092,
-0.07787446677684784,
0.055544041097164154,
0.03315753... |
PMID:12387 | Effects of benzodiazepines and pentobarbital on the evoked potentials in the cat brain. | The sites of action of benzodiazepines, diazepam and ID-540 [7-chloro-5-(o-fluorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one) on the central nervous system were examined and compared with those of pentobarbital using evoked potentials recorded on the limbic system and hypothalamus in the cat brain. Benzodia... | Effects of benzodiazepines and pentobarbital on the evoked potentials in the cat brain. The sites of action of benzodiazepines, diazepam and ID-540 [7-chloro-5-(o-fluorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one) on the central nervous system were examined and compared with those of pentobarbital using evo... | [
-0.02393949031829834,
0.00562251778319478,
0.038273993879556656,
0.041171204298734665,
0.027805132791399956,
0.04426315054297447,
0.05207313224673271,
0.037640079855918884,
0.00783053133636713,
-0.00848134234547615,
-0.056733548641204834,
-0.02396494522690773,
0.003333392785862088,
0.03507... |
PMID:12388 | Effects of L-glutamine of acetylsalicylic acid or taurocholic acid-induced gastric lesions and secretory changes in pylorus-ligated rats under normal or stress conditions. | An oral dosing of either acetylsalicylic acid (ASA) or taurocholic acid (TCA) to pylorus-ligated rats subjected to water-immersion stress produced severe damage to the gastric musoca in contrast to the irritation observed in non-stressed ones. The irritative activity of ASA or TCA on gastric mucosa under stress was dos... | Effects of L-glutamine of acetylsalicylic acid or taurocholic acid-induced gastric lesions and secretory changes in pylorus-ligated rats under normal or stress conditions. An oral dosing of either acetylsalicylic acid (ASA) or taurocholic acid (TCA) to pylorus-ligated rats subjected to water-immersion stress produced s... | [
0.0248411912471056,
0.01109207235276699,
0.018959999084472656,
0.04822046309709549,
0.008980687707662582,
0.014680162072181702,
0.06495258957147598,
0.003870030166581273,
-0.06117858737707138,
-0.06290454417467117,
0.017187872901558876,
-0.07582035660743713,
0.024915823712944984,
0.0357563... |
PMID:12389 | Studies on monoamine oxidase. XVIII. Enzymic properties of placental monoamine oxidase. | Enzymic properties of partially purified monoamine oxidase (MAO) from human placenta were studied with tyramine, serotonin and benzylamine as substrates. The highest activity was obtained with serotonin and almost no activity was observed with benzylamine. These results are similar to those obtained with rat placental ... | Studies on monoamine oxidase. XVIII. Enzymic properties of placental monoamine oxidase. Enzymic properties of partially purified monoamine oxidase (MAO) from human placenta were studied with tyramine, serotonin and benzylamine as substrates. The highest activity was obtained with serotonin and almost no activity was ob... | [
-0.0681987851858139,
0.021389493718743324,
-0.047819677740335464,
0.05920666083693504,
-0.0024148165248334408,
0.024153918027877808,
0.1071561947464943,
0.03977391868829727,
-0.05256049335002899,
-0.031895529478788376,
-0.02187003195285797,
-0.04096626117825508,
-0.003072284394875169,
0.08... |
PMID:12391 | Antagonizing effects of beta-adrenergic blockers on lucus coeruleus-induced inhibition of trigeminal nucleus neurons. | Effects of alpha- and beta-adrenergic blocking agents applied into the lateral ventricle were studied on the relay neuron in the rostral part of spinal trigeminal nucleus (STN) of cats. Conditioning stimulation of the locus coeruleus (LC) and sensory cortex (SC) inhibited the orthodromic spike generation in STN relay n... | Antagonizing effects of beta-adrenergic blockers on lucus coeruleus-induced inhibition of trigeminal nucleus neurons. Effects of alpha- and beta-adrenergic blocking agents applied into the lateral ventricle were studied on the relay neuron in the rostral part of spinal trigeminal nucleus (STN) of cats. Conditioning sti... | [
0.005329014267772436,
0.006756454706192017,
-0.00671177264302969,
0.035792842507362366,
0.012399163097143173,
0.014993514865636826,
0.03956908360123634,
0.043679263442754745,
-0.015401824377477169,
-0.05263511463999748,
-0.0007767266943119466,
-0.004879432264715433,
-0.009940648451447487,
... |
PMID:12392 | Reversible adrenergic alpha-receptor blocking action of 2,4'-dimethyl-3-piperidino-propiophenone (tolperisone). | The vascular action of 2,4'-dimethyl-3-piperidino-propiophenone hydrochloride (tolperisone hydrochloride), a centrally acting muscle relaxant, was investigated in pentobarbital anesthetized dogs. Tolperisone given intravenously produced a transient hypotension, tachycardia, and hyperventilation. The drug increased the ... | Reversible adrenergic alpha-receptor blocking action of 2,4'-dimethyl-3-piperidino-propiophenone (tolperisone). The vascular action of 2,4'-dimethyl-3-piperidino-propiophenone hydrochloride (tolperisone hydrochloride), a centrally acting muscle relaxant, was investigated in pentobarbital anesthetized dogs. Tolperisone ... | [
-0.06813935935497284,
-0.00818791426718235,
-0.022987453266978264,
0.030191518366336823,
-0.007677163928747177,
-0.0009502378525212407,
0.04894350469112396,
0.08021116256713867,
-0.01390746608376503,
-0.0355699248611927,
-0.00680767185986042,
-0.022101564332842827,
-0.03253945708274841,
-0... |
PMID:12393 | Pharmacological studies on triazine derivatives V Sedative and neuroleptic actions of 2-amino-4-[4-(2-hydroxyethyl)-piperazin-1-yl]-6-trifluoromethyl-s-triazine (TR-10). | Pharmacological properties of 2 amino-4-[4-(2-hydroxyethyl)-piperazin-1-yl]-6-trifluoromethyl-s-triazine (TR-10) were investigated in mice and rats. Chlorpromazine served as a reference compound. Tr-10 expressed in general the pharmacological profiles as neuroleptic ascertained by anti-methamphetamine activity, supress... | Pharmacological studies on triazine derivatives V Sedative and neuroleptic actions of 2-amino-4-[4-(2-hydroxyethyl)-piperazin-1-yl]-6-trifluoromethyl-s-triazine (TR-10). Pharmacological properties of 2 amino-4-[4-(2-hydroxyethyl)-piperazin-1-yl]-6-trifluoromethyl-s-triazine (TR-10) were investigated in mice and rats. C... | [
-0.05876005068421364,
0.012921538203954697,
-0.030446888878941536,
0.06248363107442856,
0.003659151028841734,
0.05391697585582733,
0.07245221734046936,
0.041761063039302826,
-0.05264783650636673,
-0.029787829145789146,
-0.030703406780958176,
0.009046063758432865,
0.022011512890458107,
0.07... |
PMID:12394 | Effects of narcotic analgesics on serotonin metabolism in brain of rats and mice. | The effects of narcotic analgesics on the brain 5-hydroxytryptamine (5-Ht) and 5-hydroxyindoleacetic acid (5-HIAA) levels of rats and mice were investigated in relation to our preceding data on the effect of humoral modulatorents. The results suggest that morphine accelerates the release of brain 5-HT both in rats and ... | Effects of narcotic analgesics on serotonin metabolism in brain of rats and mice. The effects of narcotic analgesics on the brain 5-hydroxytryptamine (5-Ht) and 5-hydroxyindoleacetic acid (5-HIAA) levels of rats and mice were investigated in relation to our preceding data on the effect of humoral modulatorents. The res... | [
-0.03189508989453316,
0.010735669173300266,
0.01692293770611286,
0.01888030208647251,
0.029150309041142464,
0.05406603217124939,
0.04432396963238716,
0.03480013459920883,
-0.018053539097309113,
-0.03699587285518646,
0.023977134376764297,
0.025386571884155273,
-0.03803456947207451,
0.037261... |
PMID:12395 | Selective alpha-adrenoceptor blocking actions of a new derivative of 2-halogenotheylamine: 6-(2-bromoethyl)-10,11-methylenedioxy-5,6,7,8-tetrahydrodibenz[c,e]azocine. | A new compound, 6-(2-bromoethyl)-10,11-methylenedioxy-5,6,7,8-tetrahydrodibenz [c,e] azocine (DA-VIII-MBr) was found to have a more selective alpha-adrenergic blocking action than dibenamine or phenoxybenzamine. From dose-response curves for adrenaline and 5-hydroxytryptamine (5-HT) obtained in strips of rat aorta befo... | Selective alpha-adrenoceptor blocking actions of a new derivative of 2-halogenotheylamine: 6-(2-bromoethyl)-10,11-methylenedioxy-5,6,7,8-tetrahydrodibenz[c,e]azocine. A new compound, 6-(2-bromoethyl)-10,11-methylenedioxy-5,6,7,8-tetrahydrodibenz [c,e] azocine (DA-VIII-MBr) was found to have a more selective alpha-adren... | [
-0.08594795316457748,
0.00154950562864542,
-0.005207484122365713,
0.03140398487448692,
-0.030665192753076553,
0.01322133932262659,
0.04473349079489708,
0.04024708643555641,
-0.04757968708872795,
-0.038226183503866196,
0.04529217258095741,
-0.028289450332522392,
-0.039249569177627563,
0.014... |
PMID:12403 | [Arteritis of the large vessels originating at the aorta (Takayasu arteritis) in childhood (author's transl)]. | A 9-month-old female child with extensive inflammatory lesions in the large arterial trunks originating at the aorta (Takayasu arteritis) was reported. Severe cerebral, intestinal and coronary circulatory disturbances as well as insufficient blood supply in both arms, particularly the left arm, developed as a result of... | [Arteritis of the large vessels originating at the aorta (Takayasu arteritis) in childhood (author's transl)]. A 9-month-old female child with extensive inflammatory lesions in the large arterial trunks originating at the aorta (Takayasu arteritis) was reported. Severe cerebral, intestinal and coronary circulatory dist... | [
-0.036230526864528656,
-0.03866405040025711,
0.005530828610062599,
0.019748352468013763,
-0.0033786494750529528,
-0.012274608947336674,
0.029650110751390457,
0.059009697288274765,
-0.006849860772490501,
0.0009706705459393561,
0.011933133006095886,
-0.0696825385093689,
-0.008028027601540089,
... |
PMID:12404 | [Cyclic AMP and plasma renin activity in renal vein blood after amitryptiline, theophylline, furosemide and beta adrenergic blocking substances (author's transl)]. | The influence of amitryptiline, theophylline and furosemide on the concentration of cyclic-AMP and plasma renin activity (PRA) was investigated in renal vein plasma. Additionally, the stimulating effect of furosemide on the PRA after application of the beta-adrenergic receptor antagonists propranolol and practolol and ... | [Cyclic AMP and plasma renin activity in renal vein blood after amitryptiline, theophylline, furosemide and beta adrenergic blocking substances (author's transl)]. The influence of amitryptiline, theophylline and furosemide on the concentration of cyclic-AMP and plasma renin activity (PRA) was investigated in renal vei... | [
-0.02598813734948635,
-0.007079042494297028,
-0.010647024028003216,
-0.014496052637696266,
0.025902394205331802,
-0.02947697788476944,
-0.002458977745845914,
0.027973631396889687,
-0.02390766516327858,
-0.0338837206363678,
0.01778910681605339,
-0.027953514829277992,
0.02938619814813137,
0.... |
PMID:12410 | [The effect of surgery, performed under ischemia, on the fine structure of the hand muscles]. | The ultrastructural picture of the intact and injured hand muscles has been examined by the authors during and after operations in tourniquet ischaemia of 12 patients, in connection with tendon and nerve reconstruction. Muscle specimina were taken partly in the beginning of the ischaemization, and partly at the end ot ... | [The effect of surgery, performed under ischemia, on the fine structure of the hand muscles]. The ultrastructural picture of the intact and injured hand muscles has been examined by the authors during and after operations in tourniquet ischaemia of 12 patients, in connection with tendon and nerve reconstruction. Muscle... | [
-0.029843466356396675,
-0.01778927631676197,
0.014933920465409756,
0.014010831713676453,
0.010011562146246433,
-0.009745614603161812,
0.06284140795469284,
0.04300305247306824,
0.021279226988554,
-0.00883953645825386,
-0.002768531907349825,
-0.023531651124358177,
-0.00046163229853846133,
0.... |
PMID:12411 | [Simultaneous occurrence of Perthes' disease, spondylolysis-spondylolisthesis and other forms of aseptic necrosis]. | Cleft formation on the lumbo-sacral spine has been observed by the authors in 15% of 32 patients with Perthes' disease--in whom follow-up examination has been performed without selection. In one case Perthes' disease was concomitant with spondylolisthesis causing no complaints. In 2 cases aspetic necrosis with other lo... | [Simultaneous occurrence of Perthes' disease, spondylolysis-spondylolisthesis and other forms of aseptic necrosis]. Cleft formation on the lumbo-sacral spine has been observed by the authors in 15% of 32 patients with Perthes' disease--in whom follow-up examination has been performed without selection. In one case Pert... | [
-0.040224745869636536,
0.006614964921027422,
0.048960842192173004,
0.025034934282302856,
-0.02145512029528618,
0.04646974802017212,
0.012913492508232594,
0.06112661957740784,
0.006572660058736801,
0.012949377298355103,
0.004748445935547352,
-0.08744876086711884,
0.031460270285606384,
0.043... |
PMID:12412 | [Axillary block anesthesia in hand surgery]. | In spite of the use of narcosis on a large scale local anaesthesia is necessary in the surgery on the hand. After the discussion of the possibilities and types of local anaesthesia the axillary blocking of the plexus brachialis is dealt with in detail, and on the basis of the experience gained with 150 cases the advant... | [Axillary block anesthesia in hand surgery]. In spite of the use of narcosis on a large scale local anaesthesia is necessary in the surgery on the hand. After the discussion of the possibilities and types of local anaesthesia the axillary blocking of the plexus brachialis is dealt with in detail, and on the basis of th... | [
0.04397789388895035,
-0.06250329315662384,
0.030697833746671677,
-0.0011043506674468517,
0.02818165346980095,
0.051932234317064285,
0.08602897822856903,
0.018153224140405655,
-0.02858460508286953,
-0.06916005909442902,
-0.03239688277244568,
0.03676769137382507,
-0.050525158643722534,
0.008... |
PMID:12408 | Thermodynamic parameters for the intramolecular disordered-to-beta transition of poly(L-tyrosine) in aqueous solution. | We have examined the disordered-to-beat transition of two samples of high molecular wieght poly(L-tyrosine), a polypeptide with an ionizing side chain, by potentiometric titration of solutions of this polymer in aqueous buffer. The degree of ionization was determined spectrophotometrically from the absorption of the ty... | Thermodynamic parameters for the intramolecular disordered-to-beta transition of poly(L-tyrosine) in aqueous solution. We have examined the disordered-to-beat transition of two samples of high molecular wieght poly(L-tyrosine), a polypeptide with an ionizing side chain, by potentiometric titration of solutions of this ... | [
-0.08468717336654663,
-0.024635599926114082,
-0.018092375248670578,
-0.004082736559212208,
-0.03363094478845596,
0.028809092938899994,
0.07190249860286713,
-0.030400626361370087,
0.018984869122505188,
-0.02386224828660488,
0.05354413762688637,
-0.04554188996553421,
0.03138585761189461,
0.0... |
PMID:12413 | [Substitution of skull defects with methyl acrylate]. | On the basis of the data of the literature and their own experiences the theoretical and pratical problems of cranioplasty are dealt with by the authors. The indications of the cranioplasty and the various materials employed are discussed. In the author's opinion, the metacrylate polymerizating to heat has been found t... | [Substitution of skull defects with methyl acrylate]. On the basis of the data of the literature and their own experiences the theoretical and pratical problems of cranioplasty are dealt with by the authors. The indications of the cranioplasty and the various materials employed are discussed. In the author's opinion, t... | [
-0.0314500592648983,
-0.009661896154284477,
0.02779320441186428,
0.0004532701859716326,
-0.029827354475855827,
0.026037031784653664,
0.008893774822354317,
0.03648588806390762,
-0.07057412713766098,
0.004920961335301399,
0.008049208670854568,
-0.042396560311317444,
-0.022202836349606514,
0.... |
PMID:12415 | [Collagen synthesis, studied by sub microscopic methods in beta-propiolactone and in tendon homografts, preserved by gamma irradiation]. | In dog experiments homologous tendos conserved in beta-propiolacton and by means of gamma-radiation have been transplanted by the authors. After the 1st, 3rd and 8th post-operative week various regions of the graft and the recipient tendon stump have been examined by means of light--, polarisation microscopic and elect... | [Collagen synthesis, studied by sub microscopic methods in beta-propiolactone and in tendon homografts, preserved by gamma irradiation]. In dog experiments homologous tendos conserved in beta-propiolacton and by means of gamma-radiation have been transplanted by the authors. After the 1st, 3rd and 8th post-operative we... | [
-0.054259322583675385,
-0.01276166457682848,
0.009791174903512001,
0.04524974524974823,
0.04665248841047287,
0.0097324438393116,
-0.019617073237895966,
0.04102373868227005,
-0.05453714728355408,
0.031407762318849564,
0.0159793421626091,
-0.059885598719120026,
-0.03867654129862785,
0.033476... |
PMID:12416 | [Surgical treatment of chemical injuries]. | Among nearly 2000 patients of a traumatological ward 82 patients were treated with chemical injury during 6 years. On the basis of their experiences the tissue damaging effect of the chemical substances as well as the methods of treatment are discussed by the authors. Dermoplastic operations have been performed in 28 i... | [Surgical treatment of chemical injuries]. Among nearly 2000 patients of a traumatological ward 82 patients were treated with chemical injury during 6 years. On the basis of their experiences the tissue damaging effect of the chemical substances as well as the methods of treatment are discussed by the authors. Dermopla... | [
-0.01260030921548605,
-0.013755198568105698,
0.07022115588188171,
-0.02557467482984066,
0.0011031230678781867,
-0.012047226540744305,
0.10147767513990402,
0.056904133409261703,
-0.07891674339771271,
-0.03143202140927315,
0.03142032399773598,
-0.047659002244472504,
-0.02185690775513649,
0.0... |
PMID:12417 | [Intramural duodenal hematoma of traumatic origin]. | A rare case of the blunt abdominal injuries--forming a clinical entity--intramural duodenal haematoma is reported. The symptoms of IMDH may appear--non specifically--after a longer interval. The diagnosis is assured in the first place by careful anamnesis and on the basis of the characteristic radiological signs. The t... | [Intramural duodenal hematoma of traumatic origin]. A rare case of the blunt abdominal injuries--forming a clinical entity--intramural duodenal haematoma is reported. The symptoms of IMDH may appear--non specifically--after a longer interval. The diagnosis is assured in the first place by careful anamnesis and on the b... | [
-0.006057365797460079,
-0.005244891159236431,
-0.036403588950634,
-0.010824496857821941,
0.011299959383904934,
-0.014025201089680195,
0.06653862446546555,
0.06673351675271988,
-0.01446258183568716,
-0.08230865001678467,
0.020236603915691376,
-0.07139697670936584,
0.0021768328733742237,
0.0... |
PMID:12419 | [Acute traumatic infratentorial subdural hematoma]. | The case of an injured man, aged 54, is reported. On the basis of the neurological symptoms, without neuro-radiological contrast examinations, in presence of negative skull osteogram, on the day of the injury suboccipital craniectomy and removal of the subdural haematoma have been performed. The diagnostical difficulti... | [Acute traumatic infratentorial subdural hematoma]. The case of an injured man, aged 54, is reported. On the basis of the neurological symptoms, without neuro-radiological contrast examinations, in presence of negative skull osteogram, on the day of the injury suboccipital craniectomy and removal of the subdural haemat... | [
-0.0030654496513307095,
-0.02383466064929962,
-0.022079022601246834,
0.008885467424988747,
0.039124585688114166,
0.0138202253729105,
0.049284614622592926,
0.062180884182453156,
-0.03838661313056946,
-0.023901235312223434,
-0.0025226306170225143,
-0.06455536931753159,
0.015131544321775436,
... |
PMID:12420 | [Mistakes, errors and their prevention in the medical expertise about accidental injuries]. | It may be stated that in the examination of the individuals who had suffered an accident, as well as in the assessment of the subsequent consequences--for whatever authority (social assurance, court of justice, State Insurance Company) the medical opinion is given--various errors may be committed, which may direct the ... | [Mistakes, errors and their prevention in the medical expertise about accidental injuries]. It may be stated that in the examination of the individuals who had suffered an accident, as well as in the assessment of the subsequent consequences--for whatever authority (social assurance, court of justice, State Insurance C... | [
-0.060309700667858124,
-0.007147578988224268,
-0.018386775627732277,
-0.003129654098302126,
0.026422714814543724,
-0.01652131788432598,
0.0804060623049736,
0.059018488973379135,
-0.007421591784805059,
-0.025247450917959213,
-0.05053205043077469,
-0.03266984224319458,
-0.009827702306210995,
... |
PMID:12423 | Immunohistochemical studies on the localization and distribution of monoamine neuron systems in the rat brain. I. Tyrosine hydroxylase in the mes- and diencephalon. | The localization and distribution of tyrosine hydroxylase (TH), the first enzyme in the catecholamine synthesis, in the mes- and diencephalon has been studied with the indirect immunofluorescence technique of Coons and collaborators. Principally, TH was present in neuron systems with a distribution similar to known dop... | Immunohistochemical studies on the localization and distribution of monoamine neuron systems in the rat brain. I. Tyrosine hydroxylase in the mes- and diencephalon. The localization and distribution of tyrosine hydroxylase (TH), the first enzyme in the catecholamine synthesis, in the mes- and diencephalon has been stud... | [
-0.005393019411712885,
-0.031306665390729904,
-0.018758632242679596,
0.025783777236938477,
-0.027699625119566917,
0.052518080919981,
0.10509924590587616,
0.020608777180314064,
0.026972481980919838,
-0.017029184848070145,
-0.0026029066648334265,
-0.06398580968379974,
-0.012833927758038044,
... |
PMID:12424 | A study of physicians' assistants in a rural setting. | In an effort to improve the health care in a rural county in Southern Appalachia, physicians' assistants (MEDEX) have been employed in the offices of three general practitioners over a three-year period. This program was evaluated using a before-after and experimental-control (county) design, utilizing data both from p... | A study of physicians' assistants in a rural setting. In an effort to improve the health care in a rural county in Southern Appalachia, physicians' assistants (MEDEX) have been employed in the offices of three general practitioners over a three-year period. This program was evaluated using a before-after and experiment... | [
-0.04075638949871063,
0.0019557815976440907,
-0.028412507846951485,
0.022855818271636963,
0.04013501852750778,
-0.042359791696071625,
0.0464363619685173,
0.024495454505085945,
-0.07792355120182037,
-0.004404941573739052,
0.033064890652894974,
0.03452588617801666,
-0.0011640525190159678,
-0... |
PMID:12425 | Adding a Medex to the medical mix: an evaluation. | Three classes of Medex were followed during their preceptorship training and subsequent employment to assess the impact of adding such physician assistants on 13 private practices. The data suggest that the Medex are readily incorporated into the practice, seeing a similar spectrum of patients and generally functioning... | Adding a Medex to the medical mix: an evaluation. Three classes of Medex were followed during their preceptorship training and subsequent employment to assess the impact of adding such physician assistants on 13 private practices. The data suggest that the Medex are readily incorporated into the practice, seeing a simi... | [
-0.05301779881119728,
-0.016567287966609,
0.013162225484848022,
-0.035924408584833145,
0.019126415252685547,
-0.013708220794796944,
0.020314684137701988,
0.006273810286074877,
-0.0034522563219070435,
-0.027033012360334396,
0.0026151298079639673,
-0.002619635546579957,
-0.02541089989244938,
... |
PMID:12448 | [Alternativity of methane assimilation pathways in obligate methylotrophs]. | The activity of key enzymes involved in the primary pathways of methane assimilation and enzymes of the citrate cycle was determined in various obligate methylotrophs: mesophilic, thermotolerant, and thermophilic. The bacteria are characterized by the membrane ultrastructure of the I type, high activity of hexosephosph... | [Alternativity of methane assimilation pathways in obligate methylotrophs]. The activity of key enzymes involved in the primary pathways of methane assimilation and enzymes of the citrate cycle was determined in various obligate methylotrophs: mesophilic, thermotolerant, and thermophilic. The bacteria are characterized... | [
-0.03654060140252113,
-0.02931446209549904,
-0.034283965826034546,
-0.0008345146779902279,
0.01449976209551096,
-0.043145060539245605,
0.017026621848344803,
0.003481992520391941,
-0.0406159907579422,
-0.05692562460899353,
0.014717943035066128,
-0.10773798078298569,
0.01225473266094923,
-0.... |
PMID:12450 | [Effect of H+, OH-, Cu2+ and Ag+ on amino acid composition of Candida utilis cells in chemostat culture]. | Amino acid composition was determined in the cells of Candida utilis VKM Y-1668 growing in the regime of chemostat. The growth was inhibited by pH of the medium, copper and silver ions, and glycerol deficiency as a control. Some specific differences have been found in the amino acid composition of the yeast depending o... | [Effect of H+, OH-, Cu2+ and Ag+ on amino acid composition of Candida utilis cells in chemostat culture]. Amino acid composition was determined in the cells of Candida utilis VKM Y-1668 growing in the regime of chemostat. The growth was inhibited by pH of the medium, copper and silver ions, and glycerol deficiency as a... | [
-0.017844511196017265,
0.013182214461266994,
-0.025661559775471687,
0.012603681534528732,
0.014005325734615326,
0.024791114032268524,
0.02481616474688053,
0.029114674776792526,
-0.03686128929257393,
-0.01791798695921898,
0.04529619216918945,
-0.08998870104551315,
0.045317642390728,
0.05739... |
PMID:12452 | [Biosynthesis of chitinase by Achromobacter liquefaciens]. | Bacterial cultures under study synthesize exocellular chitinase on a medium containing chitin or demineralized crab shells as a source of carbon and nitrogen. Conditions for biosynthesis of chitinase by the cells of Achromobacter liquefaciens 301a were investigated under periodic and continuous conditions of cultivatio... | [Biosynthesis of chitinase by Achromobacter liquefaciens]. Bacterial cultures under study synthesize exocellular chitinase on a medium containing chitin or demineralized crab shells as a source of carbon and nitrogen. Conditions for biosynthesis of chitinase by the cells of Achromobacter liquefaciens 301a were investig... | [
-0.011852032504975796,
-0.011979901231825352,
-0.07038050889968872,
-0.003717792220413685,
0.015757733955979347,
-0.04150142893195152,
0.0014457479119300842,
-0.004828088451176882,
-0.09460939466953278,
0.00603494793176651,
0.0005739570478908718,
-0.04753224179148674,
-0.0091954180970788,
... |
PMID:12457 | The physician's assistant. A controversial topic at home and abroad. | Non-physician primary care providers (physicians' assistants) have existed in under-developed or emerging nations, in various forms, for many years. It is only recently, however, that this concept has been introduced into countries with more advanced economic and medical care systems. An active and rapidly developing p... | The physician's assistant. A controversial topic at home and abroad. Non-physician primary care providers (physicians' assistants) have existed in under-developed or emerging nations, in various forms, for many years. It is only recently, however, that this concept has been introduced into countries with more advanced ... | [
-0.08734383434057236,
-0.017322028055787086,
-0.04722687974572182,
-0.01049983873963356,
0.0025193404871970415,
0.03251620754599571,
0.05273375287652016,
0.029557373374700546,
-0.07243852317333221,
0.023724325001239777,
0.060642872005701065,
0.03530611842870712,
-0.0507587306201458,
-0.045... |
PMID:12453 | [Cultivation conditions of the Aspergillus terricola mutant producing proteolytic enzyme]. | The effect of temperature, aeration and various foam suppressors on the growth of a mutant of Aspergillus terricola H-20 and on its production of proteolytic enzymes was studied. A high level of the proteolytic activity (12-15 PU/ml) was found at 28-30 degree C in conditions of aeration with the rate of oxygen dissolut... | [Cultivation conditions of the Aspergillus terricola mutant producing proteolytic enzyme]. The effect of temperature, aeration and various foam suppressors on the growth of a mutant of Aspergillus terricola H-20 and on its production of proteolytic enzymes was studied. A high level of the proteolytic activity (12-15 PU... | [
-0.05167345702648163,
0.033506158739328384,
-0.006612337194383144,
0.011228053830564022,
0.047922518104314804,
-0.03189519792795181,
0.02168307639658451,
-0.0068730576895177364,
-0.04097340255975723,
0.030067313462495804,
-0.0014855593908578157,
-0.08190245181322098,
-0.02327555976808071,
... |
PMID:12449 | [Effect of growth medium composition of glucoamylase and glycosyltransferase activity of Endomyces fibuliger]. | Production of glucoamylase and glycosyltransferase by Endomyces fibuliger was found to depend on sources of carbon and nitrogen nutrition. Starch at a concentration above 0.5% in the medium stimulated biosynthesis of glycosyltransferase but inhibited production of glucoamylase by End. fibuliger 20-9. The rate of growth... | [Effect of growth medium composition of glucoamylase and glycosyltransferase activity of Endomyces fibuliger]. Production of glucoamylase and glycosyltransferase by Endomyces fibuliger was found to depend on sources of carbon and nitrogen nutrition. Starch at a concentration above 0.5% in the medium stimulated biosynth... | [
0.004825040698051453,
-0.026853740215301514,
0.0033287429250776768,
0.0021420971024781466,
0.07256826758384705,
-0.0235174261033535,
-0.035579878836870193,
0.0011195919942110777,
-0.10593577474355698,
-0.030030494555830956,
0.03687411919236183,
-0.10356276482343674,
-0.021225465461611748,
... |
PMID:12451 | [Isolation and properties of the fibrinolytic enzyme from the Actinomyces thermovulgaris cultural broth]. | A fibrinolytic enzyme was isolated from the cultural broth of Actinomyces thermovulgaris T-54 by precipitation with ammonium sulphate to 0.8 saturation and chromatography on GE-cellulose and CM-cellulose. The enzyme is homogeneous as was confirmed by disk electrophoresis in polyacrylamide gel. Some properties of the en... | [Isolation and properties of the fibrinolytic enzyme from the Actinomyces thermovulgaris cultural broth]. A fibrinolytic enzyme was isolated from the cultural broth of Actinomyces thermovulgaris T-54 by precipitation with ammonium sulphate to 0.8 saturation and chromatography on GE-cellulose and CM-cellulose. The enzym... | [
-0.026993177831172943,
0.01930045522749424,
0.0005321680218912661,
0.007492153439670801,
0.005673389881849289,
-0.013166079297661781,
0.020786046981811523,
0.06877575814723969,
-0.06729516386985779,
-0.04014822840690613,
-0.01567629911005497,
-0.04065936058759689,
-0.032763104885816574,
-0... |
PMID:12456 | New approaches to the causation and prevention of cancers of epithelial surfaces. | Environmental rather than genetic factors appear to be responsible for the causation of cancers involving epithelial surfaces, especially oropharyngeal cancers, cancers of the gastro-intestinal tract, cancers of the liver and gall-bladder, cancers of the cervix uteri and lung cancers. Epithelial surfaces which have muc... | New approaches to the causation and prevention of cancers of epithelial surfaces. Environmental rather than genetic factors appear to be responsible for the causation of cancers involving epithelial surfaces, especially oropharyngeal cancers, cancers of the gastro-intestinal tract, cancers of the liver and gall-bladder... | [
-0.001938576577231288,
-0.017595499753952026,
0.04215915873646736,
0.03402401879429817,
-0.00011991884093731642,
-0.030754907056689262,
0.09122683107852936,
0.019662342965602875,
-0.019718335941433907,
-0.018880899995565414,
0.025253649801015854,
-0.1371641308069229,
-0.014830803498625755,
... |
PMID:12463 | Application of halide ion nuclear magnetic resonance to bioinorganic problems. | The basis for the application of halide ion nuclear magnetic resonance to the investigation of biochemical problems is reviewed and a summary of applications is presented. Anion binding to macromolecules, low molecular weight or model compounds, metalloenzymes, and extrinsic metal interactions with macromolecules are d... | Application of halide ion nuclear magnetic resonance to bioinorganic problems. The basis for the application of halide ion nuclear magnetic resonance to the investigation of biochemical problems is reviewed and a summary of applications is presented. Anion binding to macromolecules, low molecular weight or model compou... | [
-0.0896899625658989,
0.06546398252248764,
-0.0571654848754406,
-0.06746512651443481,
-0.0052528902888298035,
-0.028554368764162064,
0.03802242502570152,
0.011748547665774822,
-0.03365848958492279,
-0.05155431479215622,
0.06373150646686554,
-0.07167895138263702,
0.03047288954257965,
0.02376... |
PMID:12464 | Determination of intermediary metabolites in yeast. Critical examination of the effect of sampling conditions and recommendations for obtaining true levels. | The effect of sampling conditions on the levels of adenine nucleotides, pyridine nucleotides, glycolytic intermediates and related metabolites in yeast has been studied. A systematic examination of the conditions for harvesting has shown that it can be best accomplished by rapid filtration. Delays in the handling for r... | Determination of intermediary metabolites in yeast. Critical examination of the effect of sampling conditions and recommendations for obtaining true levels. The effect of sampling conditions on the levels of adenine nucleotides, pyridine nucleotides, glycolytic intermediates and related metabolites in yeast has been st... | [
-0.008073154836893082,
0.01987590827047825,
0.029318353161215782,
-0.015401899814605713,
0.015235972590744495,
-0.029309898614883423,
0.014755645766854286,
0.03354538977146149,
-0.04124557226896286,
-0.03837810456752777,
0.05070963501930237,
-0.05269870162010193,
-0.017752284184098244,
0.0... |
PMID:12465 | The extracellular metalloprotease of Serratia marcescens: I. Purification and characterization. | An extracellular protease of Serratia marcescens produced during growth on skim milk medium was isolated by ethanol precipitation. The protease was purified by salt fractionation, DEAE-cellulose ion exchange chromatography and gel filtration chromatography on Agarose P-100. It has a broad optimum from pH 6.0 to 9.0 and... | The extracellular metalloprotease of Serratia marcescens: I. Purification and characterization. An extracellular protease of Serratia marcescens produced during growth on skim milk medium was isolated by ethanol precipitation. The protease was purified by salt fractionation, DEAE-cellulose ion exchange chromatography a... | [
-0.09480205178260803,
-0.009300856851041317,
-0.021166261285543442,
0.0229756198823452,
0.032205987721681595,
-0.13017669320106506,
0.04172559455037117,
0.07504840940237045,
-0.06761617213487625,
-0.009629645384848118,
0.03722459450364113,
-0.02762608416378498,
-0.017687855288386345,
0.030... |
PMID:12466 | [Juvenile rheumatoid arthritis and related collagen diseases. Clinical aspects (author's transl)]. | Juvenile rheumatoid arthritis or, more correctly, juvenile chronic polyarthritis with its many clinical manifestations can be separated into the Still-syndrome with acute beginning, high fever and a high percentage of extra-articulalar, i.e. visceral symptoms, and the chronic polyarthritis in the more strict sense with... | [Juvenile rheumatoid arthritis and related collagen diseases. Clinical aspects (author's transl)]. Juvenile rheumatoid arthritis or, more correctly, juvenile chronic polyarthritis with its many clinical manifestations can be separated into the Still-syndrome with acute beginning, high fever and a high percentage of ext... | [
-0.02820032835006714,
-0.02050868421792984,
0.05419895425438881,
0.0648728609085083,
-0.019050661474466324,
0.00033922464353963733,
-0.018477018922567368,
0.08124852180480957,
-0.017028866335749626,
-0.03430720791220665,
0.02321803756058216,
-0.0569770447909832,
0.08552306890487671,
0.0165... |
PMID:12467 | [The ecology and medical importance of the Tahyna Virus (author's transl)]. | In 1958 a virus transmitted by a mosquito was isolated in the Slovakian village of Tahyna. Since this virus was unknown in Europe, a detailed study was begun. It was shown that this virus belonged to the California group of arboviruses and occurs in practically all European countries. It could very well be that young h... | [The ecology and medical importance of the Tahyna Virus (author's transl)]. In 1958 a virus transmitted by a mosquito was isolated in the Slovakian village of Tahyna. Since this virus was unknown in Europe, a detailed study was begun. It was shown that this virus belonged to the California group of arboviruses and occu... | [
0.018370090052485466,
0.01655738800764084,
-0.047981616109609604,
0.04168296605348587,
0.05823475494980812,
-0.039832670241594315,
0.037071067839860916,
0.06033068522810936,
-0.037254128605127335,
0.03738739341497421,
-0.012060430832207203,
-0.10716290026903152,
0.0026684231124818325,
0.01... |
PMID:12468 | Formation of mutagenic N-nitroso compounds from the pesticides prometryne, dodine and carbaryl in the presence of nitrite at pH 1. | Environmental chemicals including pesticides carrying secondary and tertiary amino groups are suggested to be a health hazard to man since potentially carcinogenic nitroso compounds may be formed in the presence of nitrite at low pH values resembling conditions in the human stomach. Nitrosation of the isopropylamino-tr... | Formation of mutagenic N-nitroso compounds from the pesticides prometryne, dodine and carbaryl in the presence of nitrite at pH 1. Environmental chemicals including pesticides carrying secondary and tertiary amino groups are suggested to be a health hazard to man since potentially carcinogenic nitroso compounds may be ... | [
-0.040526412427425385,
0.031631384044885635,
-0.00920113641768694,
0.01678716391324997,
0.03328558802604675,
-0.008058917708694935,
0.0700070783495903,
-0.008149496279656887,
-0.05904582142829895,
-0.0011243242770433426,
-0.018449801951646805,
-0.050754986703395844,
0.024756934493780136,
0... |
PMID:12478 | Thyrotropin releasing hormone (TRH): restoration of oxotremorine tremor in mice. Comparison with quipazine, a serotoninergic and dopaminergic stimulant. | Both TRH and quipazine (2.5-25 mg/kg) were found to restore and to intensify the oxotremorine-induced tremor in mice when injected i.p. 60 min after oxotremorine 0.5 mg/kg s.c. This phenomenon does not seem to be due to an increase in body temperature or muscle tone. Also other dopaminergic drugs, e.g. amphetamine, met... | Thyrotropin releasing hormone (TRH): restoration of oxotremorine tremor in mice. Comparison with quipazine, a serotoninergic and dopaminergic stimulant. Both TRH and quipazine (2.5-25 mg/kg) were found to restore and to intensify the oxotremorine-induced tremor in mice when injected i.p. 60 min after oxotremorine 0.5 m... | [
-0.04299577698111534,
-0.0014339201152324677,
-0.007020680699497461,
0.0730527713894844,
-0.04562545567750931,
0.014512235298752785,
0.020460112020373344,
0.02361774630844593,
-0.03461618348956108,
-0.05371331796050072,
-0.008784756064414978,
-0.019656365737318993,
0.037997134029865265,
0.... |
PMID:12477 | Interaction of benzodiazepines with neuroleptics at central dopamine neurons. | Several benzodiazepines (chlordiazepoxide, clonazepam, diazepam and flunitrazepam) markedly counteracted the elevation of the homovanillic acid (HVA) content of the rat brain induced by neuroleptics (haloperidol, pimozide, chlorpromazine, and clozapine). A similar effect was obtained with the inhibitor of GABA transami... | Interaction of benzodiazepines with neuroleptics at central dopamine neurons. Several benzodiazepines (chlordiazepoxide, clonazepam, diazepam and flunitrazepam) markedly counteracted the elevation of the homovanillic acid (HVA) content of the rat brain induced by neuroleptics (haloperidol, pimozide, chlorpromazine, and... | [
-0.06741789728403091,
0.02007012441754341,
-0.0044737388379871845,
0.05610513314604759,
0.015509674325585365,
0.03439158946275711,
0.075792096555233,
0.05571412667632103,
-0.04009133204817772,
-0.045783597975969315,
-0.026269247755408287,
-0.014146559871733189,
0.0036108349449932575,
0.074... |
PMID:12479 | Effects of enzyme induction and inhibition on microsomal oxidation of 1,4-benzodiazepines. | Metabolic oxidative profiles of diazepam (I) were obtained by aromatic C-4'-hydroxylation, N-1-demethylation, and 3-hydroxylation using a supernatant of rat liver. Incubation of 3-methyldiazepam (VI), which suppressed 3-hydroxylation, and N-1-nor-3-methyldiazepam (VII), were used to separately investigate these three o... | Effects of enzyme induction and inhibition on microsomal oxidation of 1,4-benzodiazepines. Metabolic oxidative profiles of diazepam (I) were obtained by aromatic C-4'-hydroxylation, N-1-demethylation, and 3-hydroxylation using a supernatant of rat liver. Incubation of 3-methyldiazepam (VI), which suppressed 3-hydroxyla... | [
-0.04784347862005234,
0.03567751497030258,
0.02508421055972576,
0.07016988098621368,
0.03159552812576294,
-0.025420526042580605,
-0.010150769725441933,
-0.02915731444954872,
-0.011937195435166359,
-0.04597724229097366,
-0.015494243241846561,
-0.01459155697375536,
-0.03023960068821907,
0.02... |
PMID:12480 | Restoration by histamine of the calcium-dependent electrical and mechanical response in the guinea-pig papillary muscle partially depolarized by potassium. | Electrophysiological and mechanical effects of histamine were observed in guinea-pig papillary muscle which had been depolarized and rendered inexcitable by elevation of potassium concentration in Tyrode solution to 27 mM. 1. Histamine (3 X 10(-7) to 3 X 10(-5) M) restored the action potential and tension development. ... | Restoration by histamine of the calcium-dependent electrical and mechanical response in the guinea-pig papillary muscle partially depolarized by potassium. Electrophysiological and mechanical effects of histamine were observed in guinea-pig papillary muscle which had been depolarized and rendered inexcitable by elevati... | [
-0.0559944212436676,
-0.0361090786755085,
0.031213199719786644,
0.03573482111096382,
-0.013448690995573997,
0.00862211175262928,
0.04679526388645172,
0.03679101541638374,
-0.06002739071846008,
0.0007596376235596836,
-0.0067960359156131744,
-0.10091651976108551,
-0.0062101008370518684,
-0.0... |
PMID:12481 | Inhibition by locally applied alpha-adrenoreceptor blocking drugs of the depressor response to stimulation of the anterior hypothalamus. | Cats were anaesthetized with pentobarbital sodium and the anterior hypothalamus was superfused with artificial cerebrospinal fluid through a push-pull cannula. Electrical stimulation of the superfused area with the tip of the cannula elicited a fall of the arterial blood pressure which was dependent on frequency and vo... | Inhibition by locally applied alpha-adrenoreceptor blocking drugs of the depressor response to stimulation of the anterior hypothalamus. Cats were anaesthetized with pentobarbital sodium and the anterior hypothalamus was superfused with artificial cerebrospinal fluid through a push-pull cannula. Electrical stimulation ... | [
-0.02306736260652542,
0.03908972069621086,
-0.014083311893045902,
0.04355834797024727,
-0.05288049578666687,
0.028265705332159996,
0.05349307507276535,
0.044785384088754654,
-0.01052222028374672,
-0.04498014226555824,
-0.01627834513783455,
0.016794584691524506,
0.014119732193648815,
0.0507... |
PMID:12482 | Dopaminergic neurons: reversal of effects elicited by gamma-butyrolactone by stimulation of the nigro-neostriatal pathway. | In vivo studies demonstrate that administration of gamma-butyrolactone, a precursor of gamma-hydroxybutyric acid causes a rapid increase in endogenous levels of striatal dopamine and an increase in tyrosine hydroxylase activity measured by following the short term accumulation of dihydroxyphenylalanine. The increase in... | Dopaminergic neurons: reversal of effects elicited by gamma-butyrolactone by stimulation of the nigro-neostriatal pathway. In vivo studies demonstrate that administration of gamma-butyrolactone, a precursor of gamma-hydroxybutyric acid causes a rapid increase in endogenous levels of striatal dopamine and an increase in... | [
0.0001603254786459729,
0.021483324468135834,
0.025568505749106407,
0.025968758389353752,
-0.021877460181713104,
0.05377860367298126,
-0.004786279052495956,
0.015552707947790623,
-0.027386970818042755,
-0.06303440779447556,
-0.007991500198841095,
-0.02335336245596409,
-0.039109326899051666,
... |
PMID:12483 | The action of a toxin from the sea anemone Anemonia sulcata upon Mammalian heart muscles. | The cardiac activity of toxin II, a basic polypeptide (m.w.: 4770) from the sea anemone Anemonia sulcata, was investigated in isolated electrically driven guinea-pig and rat auricles, Langendorff heart preparations of guinea-pigs and cat heart-lung preparations. Low concentrations of toxin II (2-100 nM) evoked a dose-d... | The action of a toxin from the sea anemone Anemonia sulcata upon Mammalian heart muscles. The cardiac activity of toxin II, a basic polypeptide (m.w.: 4770) from the sea anemone Anemonia sulcata, was investigated in isolated electrically driven guinea-pig and rat auricles, Langendorff heart preparations of guinea-pigs ... | [
-0.031181488186120987,
-0.04239477217197418,
-0.007916923612356186,
0.020136496052145958,
-0.001403836184181273,
-0.02067619189620018,
0.05862783268094063,
0.034737203270196915,
-0.022304274141788483,
-0.011574714444577694,
-0.0005010876921005547,
-0.0717221200466156,
-0.02649196982383728,
... |
PMID:12484 | [Clinical evaluation of oxypertine in anxiety conditions]. | Oxypertine, a new anxiolytic drug related to the indolylazine compounds, was evaluated in a group of 30 patients, the majority with severe anxiety (acute or chronic) : in some cases depression was associated. The study was performed in the Psychiatric Department at the Centro Femenil de Rehabilitación Social, in Mexico... | [Clinical evaluation of oxypertine in anxiety conditions]. Oxypertine, a new anxiolytic drug related to the indolylazine compounds, was evaluated in a group of 30 patients, the majority with severe anxiety (acute or chronic) : in some cases depression was associated. The study was performed in the Psychiatric Departmen... | [
-0.03352561965584755,
-0.016094110906124115,
-0.014822471886873245,
0.021941659972071648,
0.014239928685128689,
0.05048787593841553,
0.06755219399929047,
-0.0398409366607666,
-0.022747477516531944,
-0.07308021187782288,
0.002045548753812909,
-0.013995833694934845,
0.03088603913784027,
0.02... |
PMID:12487 | Benzodiazepine-induced modifications of dream content: the effect of flunitrazepam. | The purpose of this study was to investigate the effect of flunitrazepam, a benzodiazepine with strong hypnotic properties, on dream content. Eight normal subjects were studied in laboratory by the awakening technique, and the dream contents were rated by two judges according to nine scaled dimensions: unreality, parti... | Benzodiazepine-induced modifications of dream content: the effect of flunitrazepam. The purpose of this study was to investigate the effect of flunitrazepam, a benzodiazepine with strong hypnotic properties, on dream content. Eight normal subjects were studied in laboratory by the awakening technique, and the dream con... | [
0.004590886645019054,
0.02492010034620762,
0.04972095414996147,
0.058652859181165695,
-0.007179226726293564,
0.08041837811470032,
0.0514872781932354,
0.004656856879591942,
0.009654388763010502,
-0.06919321417808533,
-0.00774612370878458,
0.015623534098267555,
0.014584982767701149,
-0.02343... |
PMID:12490 | [Cases of enuresis nocturna treated with single reflexotherapy. Clinical and therapeutic evaluation]. | Treatment of children with nocturnal enuresis by means of acupuncture, auriculotherapy, etc. is reported. The aetiopathogenetic background, the results of treatment, and the neurophysiological mechanisms through which the action of reflexotherapy can be explained are discussed. | [Cases of enuresis nocturna treated with single reflexotherapy. Clinical and therapeutic evaluation]. Treatment of children with nocturnal enuresis by means of acupuncture, auriculotherapy, etc. is reported. The aetiopathogenetic background, the results of treatment, and the neurophysiological mechanisms through which ... | [
0.020744623616337776,
-0.0022780855651944876,
-0.01684044674038887,
0.044541481882333755,
-0.03227050602436066,
0.007898986339569092,
0.03169916197657585,
0.01902684010565281,
-0.03154641389846802,
-0.01829315535724163,
0.003917064052075148,
-0.040484990924596786,
0.013491052202880383,
0.0... |
PMID:12491 | Practolol and the safety of other beta blockers. | Recognition of the "occulomucocutaneous syndrome" related to practolol administration has caused the safety of other beta-blocking agents to come under close scrutiny. No satisfactory means of screening for at-risk patients is available. ANF estimation, has considerable limitations as both a screening and a diagnostic ... | Practolol and the safety of other beta blockers. Recognition of the "occulomucocutaneous syndrome" related to practolol administration has caused the safety of other beta-blocking agents to come under close scrutiny. No satisfactory means of screening for at-risk patients is available. ANF estimation, has considerable ... | [
-0.03475518897175789,
0.012974400073289871,
-0.007354226429015398,
0.02369680069386959,
0.006278831046074629,
0.006601389497518539,
0.0636037290096283,
0.02459830790758133,
-0.034492526203393936,
-0.04595921188592911,
0.02773471735417843,
-0.07003951817750931,
-0.025982096791267395,
0.0628... |
PMID:12492 | Primary uterine tumors and multiple endocrine adenomatosis, type I. | Multiple endocrine adenomatosis, Type I was initially diagnosed in a 35-year-old woman with primary chief cell hyperplasia of the parathyroids. Approximately 5 years later, vaginal bleeding developed and a well-differentiated endometrial adenocarcinoma was recognized. An adenomatoid tumor of the uterus was discovered i... | Primary uterine tumors and multiple endocrine adenomatosis, type I. Multiple endocrine adenomatosis, Type I was initially diagnosed in a 35-year-old woman with primary chief cell hyperplasia of the parathyroids. Approximately 5 years later, vaginal bleeding developed and a well-differentiated endometrial adenocarcinoma... | [
-0.01641649380326271,
-0.02645447850227356,
0.018249636515975,
0.022997979074716568,
0.0022141579538583755,
0.04338482767343521,
0.06487340480089188,
0.01943274587392807,
-0.022831693291664124,
-0.018582981079816818,
0.047016847878694534,
-0.006095485296100378,
0.038165170699357986,
-0.005... |
PMID:12495 | Phenylalanine hydroxylase and tyrosine aminotransferase in human fetal and adult liver. | The mean value of phenylalanine hydroxylase activity in adult human liver was almost twice as high as that in the fetal ones; no consistent variations were seen with sex, fetal age (between the 11th and 22nd week of gestation), or with hours between delivery and death. The tyrosine aminotransferase levels did not corre... | Phenylalanine hydroxylase and tyrosine aminotransferase in human fetal and adult liver. The mean value of phenylalanine hydroxylase activity in adult human liver was almost twice as high as that in the fetal ones; no consistent variations were seen with sex, fetal age (between the 11th and 22nd week of gestation), or w... | [
-0.03253597766160965,
0.00621682358905673,
-0.06032080575823784,
0.014712420292198658,
-0.030049560591578484,
0.0428432859480381,
0.06534719467163086,
0.04033242166042328,
-0.016658082604408264,
-0.006066611036658287,
0.02001097984611988,
-0.04292316734790802,
-0.008359832689166069,
0.0438... |
PMID:12496 | Failure of parathyroid hormone and cyclic AMP to inhibit renal carbonic anhydrase. | It has been suggested that the parathyroid hormone and cyclic AMP produce their bicarbonaturic effects through inhibition of renal carbonic anhydrase. In the present study, the incubation of renal carbonic anhydrase with parathyroid hormone or cyclic AMP in presence of ATP, Mg++ and K+ ions, did not produce any inhibit... | Failure of parathyroid hormone and cyclic AMP to inhibit renal carbonic anhydrase. It has been suggested that the parathyroid hormone and cyclic AMP produce their bicarbonaturic effects through inhibition of renal carbonic anhydrase. In the present study, the incubation of renal carbonic anhydrase with parathyroid horm... | [
-0.03906746581196785,
0.004880631808191538,
-0.008989582769572735,
0.06417594850063324,
-0.018590128049254417,
-0.02226204238831997,
0.03975971043109894,
0.06208678334951401,
-0.07883508503437042,
-0.03863777592778206,
0.04947514459490776,
-0.04691910371184349,
0.020735876634716988,
0.1143... |
PMID:12497 | polA6, A mutation affecting the DNA binding capacity of DNA polymerase I. | The polA6 mutation is an allele of the polA gene of Escherichia coli which produces a DNA polymerase I species readily distinguishable from that produced by the wild type allele. Experiments described here show that this enzyme has an altered pH optimum for polymerization and a lower binding affinity for DNA. The defec... | polA6, A mutation affecting the DNA binding capacity of DNA polymerase I. The polA6 mutation is an allele of the polA gene of Escherichia coli which produces a DNA polymerase I species readily distinguishable from that produced by the wild type allele. Experiments described here show that this enzyme has an altered pH ... | [
-0.08911314606666565,
0.03285279870033264,
-0.011559886857867241,
-0.05904517322778702,
0.0009646570542827249,
-0.025236312299966812,
0.06253114342689514,
0.028899040073156357,
-0.03167388588190079,
0.018421797081828117,
0.06295431405305862,
-0.017252426594495773,
-0.030060453340411186,
0.... |
PMID:12498 | Implications of electrostatic potentials on ribosomal proteins. | Potentiometric studies of ribosomal particles 30S, 50S, and 70S, were designed to investigate possible implications of the electrostatic potentials developed by the 16S and 23S rRNA fractions. Release of protons and proton titrations of these ribosomal fractions were examined as a function of Mg2+ and K+ concentrations... | Implications of electrostatic potentials on ribosomal proteins. Potentiometric studies of ribosomal particles 30S, 50S, and 70S, were designed to investigate possible implications of the electrostatic potentials developed by the 16S and 23S rRNA fractions. Release of protons and proton titrations of these ribosomal fra... | [
-0.10957147926092148,
-0.02938719093799591,
-0.019451454281806946,
-0.010456323623657227,
0.007803544867783785,
-0.004368362948298454,
0.026054734364151955,
-0.0008503433200530708,
-0.05236319825053215,
0.005802634637802839,
0.003258264623582363,
-0.04585782811045647,
0.033282943069934845,
... |
PMID:12504 | Volume changes in binding of ligands to methemoglobin and metmyoglobin. | The volume changes for the binding of various ligands to metmyoglobin and methemoglobin have been determined from the effect of pressure on the binding constants (for metmyoglobin) and by direct dilatometry (for methemoglobin). The volume changes associated with the binding of cyanide and azide ions to methemoglobin ar... | Volume changes in binding of ligands to methemoglobin and metmyoglobin. The volume changes for the binding of various ligands to metmyoglobin and methemoglobin have been determined from the effect of pressure on the binding constants (for metmyoglobin) and by direct dilatometry (for methemoglobin). The volume changes a... | [
-0.0823458656668663,
0.03865107148885727,
0.0265059657394886,
0.030983326956629753,
0.011264313012361526,
-0.03209787607192993,
0.10109220445156097,
-0.02755058743059635,
-0.022755058482289314,
-0.025373253971338272,
0.0024197588209062815,
-0.05286880210042,
0.002393170725554228,
0.0351204... |
PMID:12505 | Dopamine receptors in human and calf brains, using [3H]apomorphine and an antipsychotic drug. | In order to develop a better dopamine receptor radioligand, [3H[apomorphine was prepared and tested for dopamine-like binding properties in both calf and human brain tissues. Specific binding of [3H]apomorphine was defined as that binding which occurred in the presence of 1 muM (-)-butaclamol (an inactive neuroleptic) ... | Dopamine receptors in human and calf brains, using [3H]apomorphine and an antipsychotic drug. In order to develop a better dopamine receptor radioligand, [3H[apomorphine was prepared and tested for dopamine-like binding properties in both calf and human brain tissues. Specific binding of [3H]apomorphine was defined as ... | [
-0.015288281254470348,
-0.025749899446964264,
-0.006570656783878803,
0.05499913543462753,
-0.035355616360902786,
-0.008872518315911293,
0.09326992183923721,
0.018210798501968384,
-0.030485689640045166,
-0.01660311594605446,
-0.004227848723530769,
-0.05625578388571739,
-0.04271455481648445,
... |
PMID:12503 | [Effect of several factors on the process of protein solution ultrafiltration]. | Ultrafiltration of protein solutions was investigated, using deoxyribonuclease of Actinomyces streptomycini filtered through a membrane based on vinylpyrrolidone-methyl methacrylate copolymers. It was shown that ionization of the protein molecule, level of the applied pressure as well as the protein concentration in th... | [Effect of several factors on the process of protein solution ultrafiltration]. Ultrafiltration of protein solutions was investigated, using deoxyribonuclease of Actinomyces streptomycini filtered through a membrane based on vinylpyrrolidone-methyl methacrylate copolymers. It was shown that ionization of the protein mo... | [
-0.06587251275777817,
-0.02132485993206501,
-0.011270132847130299,
-0.03513669595122337,
-0.03409699723124504,
-0.06371655315160751,
0.028318511322140694,
0.05944150313735008,
-0.02499648928642273,
-0.0038299299776554108,
-0.02076626941561699,
-0.017872188240289688,
0.047509320080280304,
0... |
PMID:12506 | Isolation of 3-phosphohistidine from phosphorylated pyruvate, phosphate dikinase. | Pyruvate, phosphate dikinase (EC 2-7-9-1) catalyzes formation of phosphoenolpyruvate, AMP, and inorganic pyrophosphate from pyruvate, ATP, and orthophosphate. A pyrophosphoryl and phosphoryl form of the enzyme is involved in this transfer. The [32P]phosphoryl form of pyruvate, phosphate dikinase was prepared with enzym... | Isolation of 3-phosphohistidine from phosphorylated pyruvate, phosphate dikinase. Pyruvate, phosphate dikinase (EC 2-7-9-1) catalyzes formation of phosphoenolpyruvate, AMP, and inorganic pyrophosphate from pyruvate, ATP, and orthophosphate. A pyrophosphoryl and phosphoryl form of the enzyme is involved in this transfer... | [
-0.08382789045572281,
-0.05364726483821869,
-0.006610895972698927,
-0.028572559356689453,
0.02183287777006626,
-0.07611937820911407,
-0.022911394014954567,
0.016280628740787506,
-0.07515065371990204,
-0.005851902067661285,
0.0767710879445076,
-0.08805181086063385,
-0.03745252266526222,
0.0... |
PMID:12507 | Phosphorus nuclear magnetic resonance studies on normoxic and ischemic cardiac tissue. | The intact heart of a young rat was excised rapidly and cooled to 0 degree C; its energy-rich compounds were examined by 31P Fourier Transform nuclear magnetic resonance. The heart showed the characteristic spectrum of sugar phosphates, inorganic phosphate, phosphocreatine, and magniesium phates, inorganic phosphate, p... | Phosphorus nuclear magnetic resonance studies on normoxic and ischemic cardiac tissue. The intact heart of a young rat was excised rapidly and cooled to 0 degree C; its energy-rich compounds were examined by 31P Fourier Transform nuclear magnetic resonance. The heart showed the characteristic spectrum of sugar phosphat... | [
-0.03183402121067047,
0.027832496911287308,
0.054210104048252106,
-0.008994277566671371,
0.026235291734337807,
-0.005611409433186054,
0.05315200239419937,
0.015285006724298,
-0.05731607973575592,
-0.04655520245432854,
0.02013867162168026,
-0.0838727205991745,
-0.010793818160891533,
0.01829... |
PMID:12508 | Role of the intrinsic transglutaminase in the Ca2+-mediated crosslinking of erythrocyte proteins. | Transamidase (i.e., "transglutaminase") activity of human erythrocytes, lysed by a single freezing and thawing to 37 degrees, was measured by a method of incorporating [14C]putrescine into N,N'-dimethylcasein. In the absence of added calcium ions, virtually no enzyme activity could be detected. An increase in concentra... | Role of the intrinsic transglutaminase in the Ca2+-mediated crosslinking of erythrocyte proteins. Transamidase (i.e., "transglutaminase") activity of human erythrocytes, lysed by a single freezing and thawing to 37 degrees, was measured by a method of incorporating [14C]putrescine into N,N'-dimethylcasein. In the absen... | [
-0.07865743339061737,
-0.03235132247209549,
-0.07932507246732712,
0.02141973376274109,
-0.010216506198048592,
-0.031757790595293045,
0.11344599723815918,
0.05587545037269592,
-0.03333088010549545,
0.010680046863853931,
0.0055172801949083805,
-0.08198819309473038,
-0.025330763310194016,
0.1... |
PMID:12509 | Proline and glycine uptake by renal brushborder membrane vesicles. | Uptake of L-proline and glycine by rat renal brushborder membrane vesicles was seen to be osmotically sensitive, pH dependent,and occurred in the absence of proline and glycine metabolism. The uptake system for proline was Na+ gradient dependent, and exhibited a dual system for entry, Km1 = 0.067 mM and Km2 = 5.26 mM. ... | Proline and glycine uptake by renal brushborder membrane vesicles. Uptake of L-proline and glycine by rat renal brushborder membrane vesicles was seen to be osmotically sensitive, pH dependent,and occurred in the absence of proline and glycine metabolism. The uptake system for proline was Na+ gradient dependent, and ex... | [
-0.09466458857059479,
-0.01048244908452034,
-0.03063323348760605,
0.001732911099679768,
0.016677750274538994,
-0.03730781748890877,
0.05000366270542145,
0.0009770079050213099,
-0.050099264830350876,
-0.006971291732043028,
0.010216055437922478,
-0.10156113654375076,
0.028743982315063477,
0.... |
PMID:12518 | Discriminative stimulus properties of fentanyl and morphine: tolerance and dependence. | Using a food-reinforced two-lever operant procedure, rats were trained to discriminate 0.04 mg/kg fentanyl from saline. At different time intervals after the establishment of discriminative responding, stimulus generalization experiments were performed with equivalent dose ranges of fentanyl (0.0025 to 0.02 mg/kg) and ... | Discriminative stimulus properties of fentanyl and morphine: tolerance and dependence. Using a food-reinforced two-lever operant procedure, rats were trained to discriminate 0.04 mg/kg fentanyl from saline. At different time intervals after the establishment of discriminative responding, stimulus generalization experim... | [
-0.005251794122159481,
-0.017008043825626373,
-0.026570653542876244,
0.009167996235191822,
0.03172890096902847,
0.05884190648794174,
0.07271028310060501,
0.01907184161245823,
-0.036571040749549866,
-0.03697580844163895,
-0.03465459123253822,
0.004221239127218723,
0.0014027543365955353,
0.0... |
PMID:12519 | Early processing of visual information. | An introduction is given to a theory of early visual information processing. The theory has been implemented, and examples are given of images at various stages of analysis. It is argued that the first step of consequence is to compute a primitive but rich description of the grey-level changes present in an image. The ... | Early processing of visual information. An introduction is given to a theory of early visual information processing. The theory has been implemented, and examples are given of images at various stages of analysis. It is argued that the first step of consequence is to compute a primitive but rich description of the grey... | [
-0.014319664798676968,
0.007767726667225361,
-0.024077309295535088,
0.0014892893377691507,
0.03678823262453079,
0.033715058118104935,
0.03441561758518219,
-0.0036699995398521423,
0.028488531708717346,
0.04805021733045578,
0.03170973062515259,
-0.04554591327905655,
0.009948298335075378,
0.0... |
PMID:12520 | Modification of the noradrenaline related effects of smoking by beta-blockade. | Increases in plasma noradrenaline were found in a group of 12 subjects smoking cigarettes. The associated rises in pulse rate, blood pressure and plasma free fatty acids could be prevented by beta-blockade with oxprenolol. This inhibition of the peripheral effects of catecholamines did not affect subjective satisfactio... | Modification of the noradrenaline related effects of smoking by beta-blockade. Increases in plasma noradrenaline were found in a group of 12 subjects smoking cigarettes. The associated rises in pulse rate, blood pressure and plasma free fatty acids could be prevented by beta-blockade with oxprenolol. This inhibition of... | [
-0.006332690827548504,
0.06568949669599533,
-0.0013967840932309628,
0.047510575503110886,
-0.0016581930685788393,
0.0251171812415123,
0.039759088307619095,
-0.03325291723012924,
0.0008304620278067887,
-0.06304594874382019,
-0.031928692013025284,
-0.012736010365188122,
-0.008230014704167843,
... |
PMID:12521 | Psychoactive drug effect on behavioural changes induced by prolonged socio-environmental deprivation in rats. | Several so-called 'non-specific' or 'non-drug' factors are known to interfere with the response to psychotropic drug administration. Animal emotionality has been reported to change the outcome of psychoactive drug administration, so that the response to a stimulant or depressant drug may considerably change according t... | Psychoactive drug effect on behavioural changes induced by prolonged socio-environmental deprivation in rats. Several so-called 'non-specific' or 'non-drug' factors are known to interfere with the response to psychotropic drug administration. Animal emotionality has been reported to change the outcome of psychoactive d... | [
0.015921253710985184,
0.01495804637670517,
0.05710621923208237,
0.0005178847932256758,
0.004285304807126522,
0.02834559790790081,
0.05510759726166725,
-0.004829897079616785,
-0.02447589859366417,
-0.028652381151914597,
0.024798128753900528,
-0.006948155350983143,
-0.022656310349702835,
0.0... |
PMID:12522 | Amino acid precursors of monoamine neurotransmitters and some factors influencing their supply to the brain. | There is evidence that changes in the concentrations of the monoamine neurotransmitters within the brain are associated with changes in mental processes, with disorders of control of movement and with certain neuropsychiatric diseases. These neurotransmitters are synthesized in the brain from aromatic amino acid precur... | Amino acid precursors of monoamine neurotransmitters and some factors influencing their supply to the brain. There is evidence that changes in the concentrations of the monoamine neurotransmitters within the brain are associated with changes in mental processes, with disorders of control of movement and with certain ne... | [
-0.03302697837352753,
-0.012217477895319462,
-0.04508117958903313,
0.006797898095101118,
-0.052673935890197754,
0.10146439075469971,
0.11001218110322952,
-0.01963510364294052,
0.028099285438656807,
-0.0032113685738295317,
0.018982499837875366,
-0.035708364099264145,
0.023282835260033607,
0... |
PMID:12524 | Effects of chlordiazepoxide, ripazepam and d-amphetamine on conditioned acceleration of timing behaviour in rats. | The lever-pressing behaviour of three rats was maintained by a schedule in which food reinforcement was obtained by any response which was emitted at least 15 s after the previous response (DRL 15s). When performance on this schedule had stabilised, the animals were presented intermittently with 1-min periods of a whit... | Effects of chlordiazepoxide, ripazepam and d-amphetamine on conditioned acceleration of timing behaviour in rats. The lever-pressing behaviour of three rats was maintained by a schedule in which food reinforcement was obtained by any response which was emitted at least 15 s after the previous response (DRL 15s). When p... | [
-0.08563951402902603,
0.05521239712834358,
0.07137272506952286,
0.024906113743782043,
-0.023316819220781326,
0.06724125891923904,
0.05230513960123062,
0.0108434883877635,
-0.040729887783527374,
-0.0768384039402008,
-0.0022533005103468895,
-0.0001849889667937532,
0.00013220806431490928,
0.0... |
PMID:12525 | Head twitches induced by benzodiazepines and the role of biogenic amines. | Clonazepam, one of the benzodiazepines, induced head twitches in mice in a dose-dependent manner and sustained them for at least 120 min. Some of the benzodiazepines such as nitrazepam, fludiazepam, and nimetazepam also significantly induced head twitches at doses higher than 10 mg/kg, but other benzodiazepines like di... | Head twitches induced by benzodiazepines and the role of biogenic amines. Clonazepam, one of the benzodiazepines, induced head twitches in mice in a dose-dependent manner and sustained them for at least 120 min. Some of the benzodiazepines such as nitrazepam, fludiazepam, and nimetazepam also significantly induced head... | [
-0.033436618745326996,
0.012479083612561226,
0.04282796382904053,
0.008781198412179947,
-0.0048099663108587265,
0.008121540769934654,
0.06010037288069725,
0.03286658227443695,
-0.015294520184397697,
-0.048417992889881134,
-0.03947998955845833,
-0.023182740435004234,
-0.061921022832393646,
... |
PMID:12526 | Action of enpiprazole on emotional behavior induced by hypothalamic stimulation in rats and cats. | Action of enpiprazole on emotional behavior elicited by hypothalamic stimulation in rats and cats was investigated and comparisons were made with effects of diazepam. Two behavioral patterns were elicited by stimulation of the postero-medial part of the hypothalamus in rats: a food-carrying response beginning with expl... | Action of enpiprazole on emotional behavior induced by hypothalamic stimulation in rats and cats. Action of enpiprazole on emotional behavior elicited by hypothalamic stimulation in rats and cats was investigated and comparisons were made with effects of diazepam. Two behavioral patterns were elicited by stimulation of... | [
-0.024469492956995964,
0.0033149863593280315,
0.028534669429063797,
0.05509963259100914,
0.0002767815603874624,
0.03297063335776329,
0.06708353757858276,
0.044151224195957184,
-0.03205733373761177,
-0.022758416831493378,
-0.03162919729948044,
-0.018891721963882446,
0.014371159486472607,
0.... |
PMID:12527 | Single and repeated administration of neuroleptic drugs to rats: effects on striatal dopamine-sensitive adenylate cyclase and locomotor activity produced by tranylcypromine and L-tryptophan or L-Dopa. | Injection of tranylcypromine and L-tryptophan results in rats displaying behavioural changes including hyperactivity, probably due to stimulation of post-synaptic 5-hydroxytryptamine (5-HT) receptors. Increased locomotor activity of a different type is elicited by injection of tranylcypromine and L-dopa, a procedure wh... | Single and repeated administration of neuroleptic drugs to rats: effects on striatal dopamine-sensitive adenylate cyclase and locomotor activity produced by tranylcypromine and L-tryptophan or L-Dopa. Injection of tranylcypromine and L-tryptophan results in rats displaying behavioural changes including hyperactivity, p... | [
-0.046119749546051025,
0.028683528304100037,
0.03587277606129646,
0.014129791408777237,
-0.0412621945142746,
0.04394466057419777,
0.05314325913786888,
0.038284994661808014,
-0.021324878558516502,
-0.04883669689297676,
0.05613674595952034,
0.02822803519666195,
-0.014140033163130283,
0.06334... |
PMID:12528 | Effects of pyrroxan and chlordiazepoxide on biogenic amine metabolism in the rat brain. | Pyrroxan (20 mg/kg, i.p.), a new potential antianxiety agent, increased brain norepinephrine (NE) turnover in rats, reflecting a possible central alpha-adrenergic receptor blocking activity. In contrast, chlordiazepoxide (20 mg/kg, i.p.), a widely used antianxiety agent, did not alter the NE turnover. Pyrroxan did not ... | Effects of pyrroxan and chlordiazepoxide on biogenic amine metabolism in the rat brain. Pyrroxan (20 mg/kg, i.p.), a new potential antianxiety agent, increased brain norepinephrine (NE) turnover in rats, reflecting a possible central alpha-adrenergic receptor blocking activity. In contrast, chlordiazepoxide (20 mg/kg, ... | [
-0.03343053534626961,
0.08419844508171082,
0.04487814009189606,
0.02012461982667446,
-0.002095466246828437,
0.03272361680865288,
0.06882870942354202,
0.00047228121547959745,
-0.05657704547047615,
-0.08790366351604462,
-0.03808825463056564,
0.01959119364619255,
0.0000334820470015984,
0.0521... |
PMID:12529 | Investigations of the mechanism of central action of kinins. | The effects of kinins on the level of norepinephrine, dopamine, and serotonin and on their metabolites, i.e., normetanephrine, homovanillic acid, and 5-hydroxyindoloacetic acid in the brain tissue divided into cerebellum, corpus striatum, cortex, hippocampus, hypothalamus, medulla oblongata, and midbrain were investiga... | Investigations of the mechanism of central action of kinins. The effects of kinins on the level of norepinephrine, dopamine, and serotonin and on their metabolites, i.e., normetanephrine, homovanillic acid, and 5-hydroxyindoloacetic acid in the brain tissue divided into cerebellum, corpus striatum, cortex, hippocampus,... | [
-0.014006882905960083,
-0.025005297735333443,
-0.022455718368291855,
0.009236110374331474,
0.01297856867313385,
0.043009884655475616,
0.05237163230776787,
0.03755386918783188,
-0.03343505784869194,
-0.04745073616504669,
0.04552061855792999,
0.012774063274264336,
0.036618880927562714,
0.058... |
PMID:12530 | Sleep disorder and psychobiological symptomatology in male psychiatric outpatients and male nonpatients. | Sleep disturbance was studied in relation to psychiatric and physical symptoms for 214 male psychiatric outpatients and 248 male nonpatients. Our self-report instrument required that subjects describe the frequency of symptoms precisely on a five-point scale from "every day" to "not at all." Percentages are based on th... | Sleep disorder and psychobiological symptomatology in male psychiatric outpatients and male nonpatients. Sleep disturbance was studied in relation to psychiatric and physical symptoms for 214 male psychiatric outpatients and 248 male nonpatients. Our self-report instrument required that subjects describe the frequency ... | [
0.011656157672405243,
0.0640256255865097,
0.0069568525068461895,
0.017660638317465782,
-0.0014154970413073897,
0.015523598529398441,
0.06638312339782715,
0.011120369657874107,
0.024616288021206856,
0.001423340872861445,
0.011321078054606915,
-0.03362882882356644,
-0.016480153426527977,
0.0... |
PMID:12535 | Intraperitoneal and retroperitoneal hemorrhage. | Besides blunt and penetrating trauma, many diseases spontaneously produce abdominal hemorrhage. Here the term "spontaneous" implies the lack of observable injury, but the likelihood that unrecognized trauma initiates blood loss which continues unabated when clotting factors are absent or depleted. Survival of the patie... | Intraperitoneal and retroperitoneal hemorrhage. Besides blunt and penetrating trauma, many diseases spontaneously produce abdominal hemorrhage. Here the term "spontaneous" implies the lack of observable injury, but the likelihood that unrecognized trauma initiates blood loss which continues unabated when clotting facto... | [
-0.02719247341156006,
-0.0460299588739872,
-0.026154272258281708,
0.0300629623234272,
-0.014809168875217438,
0.011080958880484104,
0.0646301656961441,
0.09050851315259933,
0.016818154603242874,
0.002020405139774084,
0.03364972397685051,
-0.06735050678253174,
-0.01966259814798832,
0.0248125... |
PMID:12531 | Stages of bone marrow transplantation: a psychiatric perspective. | Patients undergoing bone marrow transplantation were closely followed by a psychiatric service functioning as part of a multidisciplinary team. A somewhat predictable pattern of psychological reactions to the stress of various stages of the procedure appeared to emerge. Approaches to patient evaluation, typical patient... | Stages of bone marrow transplantation: a psychiatric perspective. Patients undergoing bone marrow transplantation were closely followed by a psychiatric service functioning as part of a multidisciplinary team. A somewhat predictable pattern of psychological reactions to the stress of various stages of the procedure app... | [
-0.03563714027404785,
0.06512962281703949,
0.012383581139147282,
-0.036016955971717834,
-0.007960468530654907,
0.05050082877278328,
0.03435971587896347,
0.0252282302826643,
-0.0050179967656731606,
-0.0696115493774414,
0.0519428476691246,
-0.019397303462028503,
-0.03546609356999397,
-0.0407... |
PMID:12538 | The chemical structure of prostaglandin X (prostacyclin). | The chemical structure of prostaglandin X, the anti-aggregatory substance derived from prostaglandin endoperoxides, is 9-deoxy-6, 6alpha-epoxy-delta5-PGF1alpha. The stable compound formed when prostaglandin X undergoes a chemical transformation in biological systems in 6-keto-PGF1alpha. Prostaglandin X is stabilized in... | The chemical structure of prostaglandin X (prostacyclin). The chemical structure of prostaglandin X, the anti-aggregatory substance derived from prostaglandin endoperoxides, is 9-deoxy-6, 6alpha-epoxy-delta5-PGF1alpha. The stable compound formed when prostaglandin X undergoes a chemical transformation in biological sys... | [
-0.09152805060148239,
-0.005465335678309202,
-0.009951764717698097,
0.004863644950091839,
-0.002142854267731309,
0.03848319500684738,
0.03635279834270477,
-0.011132176965475082,
-0.04661181569099426,
-0.02463355101644993,
0.049966536462306976,
-0.03373227268457413,
0.061446741223335266,
-0... |
PMID:12539 | Biosynthesis of thromboxane B2: assay, isolation, and properties of the enzyme system in human platelets. | The microsomal fraction of human platelets catalyzed the conversion of arachidonic acid to an unstable platelet-aggregating factor and a hydrolyzed product on the thin-layer chromatography (TLC). This product was isolated on TLC, purified by silica gel column chromatography and identified by combined gas chromatography... | Biosynthesis of thromboxane B2: assay, isolation, and properties of the enzyme system in human platelets. The microsomal fraction of human platelets catalyzed the conversion of arachidonic acid to an unstable platelet-aggregating factor and a hydrolyzed product on the thin-layer chromatography (TLC). This product was i... | [
-0.10444153845310211,
0.011139914393424988,
-0.09283667057752609,
0.00027352815959602594,
-0.00969334039837122,
-0.004167797975242138,
0.026674330234527588,
0.05400312691926956,
-0.08496555685997009,
-0.01266416348516941,
0.022259144112467766,
-0.07328104227781296,
-0.037550199776887894,
0... |
PMID:12543 | [Effect of the ionic environment and of various neurotransmitters on spontaneous motility in snail intestine (author's transl)]. | A spontaneous rhythmic motility of the isolated intestine in snail, Chryptomphalus hortensis, has been registered at 30 degrees C with the aid of an electronic transductor and an appropriate amplification. These slow regular movements are affected by ionic composition changes in the suspension medium. Na+, K+ and Ca++ ... | [Effect of the ionic environment and of various neurotransmitters on spontaneous motility in snail intestine (author's transl)]. A spontaneous rhythmic motility of the isolated intestine in snail, Chryptomphalus hortensis, has been registered at 30 degrees C with the aid of an electronic transductor and an appropriate ... | [
-0.034626033157110214,
-0.059182681143283844,
-0.004648955073207617,
0.051989782601594925,
-0.039634231477975845,
-0.03856844827532768,
0.05975082144141197,
-0.016226034611463547,
-0.05076020210981369,
-0.02942570112645626,
0.025900695472955704,
-0.10528688877820969,
-0.005196439102292061,
... |
PMID:12544 | Participation of leukemia cells in immune responses. | Cells of a transplantable lymphoid leukemia of mice were tested in vivo and in vitro to see which features of normal lymphoid cells were retained in spite of malignant transformation and lack of growth control. Leukemia cells phagocytosed, adhered to glass, possessed receptors for immunoglobulin, participated in the im... | Participation of leukemia cells in immune responses. Cells of a transplantable lymphoid leukemia of mice were tested in vivo and in vitro to see which features of normal lymphoid cells were retained in spite of malignant transformation and lack of growth control. Leukemia cells phagocytosed, adhered to glass, possessed... | [
-0.04757659137248993,
0.023151269182562828,
-0.05387720838189125,
-0.0017751717241480947,
0.0017559555126354098,
-0.04741499945521355,
0.08578107506036758,
0.0734102800488472,
-0.07159730046987534,
0.02992657572031021,
0.03026045486330986,
-0.048763494938611984,
-0.006548827048391104,
-0.0... |
PMID:12542 | [The concept of risk in parasitic diseases with special reference to malaria (author's transl)]. | The concept of risk, its components and their interrelationship are described. Emphasis has been placed on the value of the variables to be taken into account in the selection of intervention measures: -- for the mosquito: the daily frequency of blood meals taken from man, the duration of the sporogonic cycle, the dail... | [The concept of risk in parasitic diseases with special reference to malaria (author's transl)]. The concept of risk, its components and their interrelationship are described. Emphasis has been placed on the value of the variables to be taken into account in the selection of intervention measures: -- for the mosquito: ... | [
0.005985943600535393,
0.02210204303264618,
0.014260097406804562,
0.006013373378664255,
0.02380530908703804,
-0.04266621172428131,
0.09934356808662415,
0.07584552466869354,
0.019495779648423195,
0.003666143398731947,
0.008773053996264935,
-0.04675722494721413,
0.012680955231189728,
0.032594... |
PMID:12548 | Antagonism by naloxone of morphine-induced single-dose dependence and antinociception in mice. | Single-dose physical dependence on morphine, as indicated by the mouse withdrawal jumping test, was reduced in a dose-related fashion by co-administration of naloxone. In the same dose range, naloxone also antagonized the antinociceptive effect of morphine in the mouse writhing test. Dose-response data revealed essenti... | Antagonism by naloxone of morphine-induced single-dose dependence and antinociception in mice. Single-dose physical dependence on morphine, as indicated by the mouse withdrawal jumping test, was reduced in a dose-related fashion by co-administration of naloxone. In the same dose range, naloxone also antagonized the ant... | [
-0.05238065496087074,
0.010992410592734814,
0.027501974254846573,
0.01274828054010868,
0.02184167690575123,
0.022013798356056213,
0.06654787808656693,
0.050355516374111176,
-0.06552822142839432,
-0.05253740772604942,
0.026361308991909027,
0.02124633640050888,
-0.04641886055469513,
0.019237... |
PMID:12549 | Changes in brain catecholamines and spontaneous locomotor activity in response to thyrotropin releasing hormone. | Repeated exposure of rats to thyrotropin releasing hormone produced a dose- and time-dependent increase in spontaneous locomotor activity accompanied by an increase in brain stem tyrosine hydroxylase. Dopamine levels in cerebral cortex were increased maximally by 34% in animals receiving thyrotropin releasing hormone a... | Changes in brain catecholamines and spontaneous locomotor activity in response to thyrotropin releasing hormone. Repeated exposure of rats to thyrotropin releasing hormone produced a dose- and time-dependent increase in spontaneous locomotor activity accompanied by an increase in brain stem tyrosine hydroxylase. Dopami... | [
-0.024030502885580063,
0.03216340392827988,
-0.00976387970149517,
0.01629963330924511,
-0.029316673055291176,
0.04955810680985451,
0.03331323340535164,
0.010390069335699081,
-0.02578800916671753,
-0.0382770411670208,
-0.001101059839129448,
-0.016855988651514053,
-0.023028558120131493,
0.08... |
PMID:12551 | Vasomotor rhinitis: psychosomatic conditions and treatment. | The importance of the autonomic nervous system in vasomotor conditions of the nose was outlined. The symptoms, findings and differential diagnosis of the vasomator rhinitis were reviewed. Reference is made to the applied treatment and results obtained with different antistaminics in 2150 patients. | Vasomotor rhinitis: psychosomatic conditions and treatment. The importance of the autonomic nervous system in vasomotor conditions of the nose was outlined. The symptoms, findings and differential diagnosis of the vasomator rhinitis were reviewed. Reference is made to the applied treatment and results obtained with dif... | [
0.026415830478072166,
0.0027251793071627617,
-0.010429219342768192,
0.07326146960258484,
-0.017811760306358337,
0.006431954447180033,
0.10412713140249252,
-0.005492673721164465,
-0.053486019372940063,
-0.005994243547320366,
-0.012849792838096619,
-0.014148767106235027,
-0.008479679934680462,... |
PMID:12554 | Improvement in the quality of enzyme determinations by Scandinavian laboratories upon introduction of Scandinavian recommended methods. | The last annual Scandinavian proficiency survey (January 1975) offered an opportunity to evaluate the effect of the introduction of recommended methods for ASAT, ALAT, LD, and ALP on routinely performed enzyme determinations in clinical chemical laboratories. The results obtained by the recommended methods showed a mar... | Improvement in the quality of enzyme determinations by Scandinavian laboratories upon introduction of Scandinavian recommended methods. The last annual Scandinavian proficiency survey (January 1975) offered an opportunity to evaluate the effect of the introduction of recommended methods for ASAT, ALAT, LD, and ALP on r... | [
-0.007029703818261623,
0.034624598920345306,
-0.05234484747052193,
0.0032428535632789135,
0.010276101529598236,
0.010887077078223228,
0.02766701951622963,
0.08593090623617172,
0.008351941592991352,
-0.034561749547719955,
0.06685616075992584,
-0.03530649095773697,
-0.035538699477910995,
0.0... |
PMID:12555 | A method for enzymatic determination of citrate in serum and urine. | A method for determination of citrate in serum and urine using citrate lyase is described. The influence of pH, zinc, magnesium, and calcium ions on the reaction velocity is studied. Citrate lyase activity is found rather insensitive to variations in pH round the pH-optimum at 8.2. Zinc ions activate the reactions. The... | A method for enzymatic determination of citrate in serum and urine. A method for determination of citrate in serum and urine using citrate lyase is described. The influence of pH, zinc, magnesium, and calcium ions on the reaction velocity is studied. Citrate lyase activity is found rather insensitive to variations in p... | [
-0.037401456385850906,
-0.00144387676846236,
-0.00956855621188879,
0.047544680535793304,
-0.0013643719721585512,
-0.07448764890432358,
0.12598907947540283,
0.06789540499448776,
-0.04309741407632828,
0.01163775660097599,
0.043650127947330475,
-0.07445463538169861,
0.024037698283791542,
0.03... |
PMID:12552 | Clinical assessment of cryptorchid boys by determination of urinary testosterone glucuronide following large doses of human chorionic gonadotropin (hCG). | Urinary TG and fractionated 17-ketosteroid (Drosdowsky) determinations were performed before and after the intramuscular administration of 15,000 IU of human chorionic gonadotropin (hCG) in 10 sexually immature healthy boys and in 12 bilaterally cryptorchid boys. The same basal determinations were made in 11 gonadless ... | Clinical assessment of cryptorchid boys by determination of urinary testosterone glucuronide following large doses of human chorionic gonadotropin (hCG). Urinary TG and fractionated 17-ketosteroid (Drosdowsky) determinations were performed before and after the intramuscular administration of 15,000 IU of human chorioni... | [
0.02674635872244835,
0.022339235991239548,
0.012053921818733215,
-0.016398634761571884,
-0.006712666247040033,
-0.006231080740690231,
0.039521247148513794,
0.04925485700368881,
-0.06248196214437485,
-0.020159294828772545,
0.031211325898766518,
-0.10273478925228119,
0.03874532878398895,
0.0... |
PMID:12556 | Transferrin and iron uptake by isolated rat liver mitochondria. | Isolated rat liver mitochondria accumulate iron from the suspending medium when [59Fe]transferrin is used as a model compound. The accumulation proceeds by two different mechanisms, i.e. by an energy-independent and an energy-dependent (uncoupler sensitive) mechanism, which have different time, pH, and temperature depe... | Transferrin and iron uptake by isolated rat liver mitochondria. Isolated rat liver mitochondria accumulate iron from the suspending medium when [59Fe]transferrin is used as a model compound. The accumulation proceeds by two different mechanisms, i.e. by an energy-independent and an energy-dependent (uncoupler sensitive... | [
-0.060512837022542953,
-0.006076762452721596,
-0.08765516430139542,
0.04523961991071701,
0.043766047805547714,
-0.01455882377922535,
0.06836077570915222,
0.016705654561519623,
-0.07632376253604889,
-0.029363548383116722,
0.0942905843257904,
-0.07921969145536423,
0.034806907176971436,
0.014... |
PMID:12553 | [Use of a monomaxillary curved splint in maxillofacial surgery]. | We describe a prefabricated monomaxillary arch, fitted with perpendicular supports with a main bar which provides dento-maxillary setting in the antero-posterior direction and also vertically since it is possible to attach it to the free edge of the teeth. The indications concerning the use of this arch are given in de... | [Use of a monomaxillary curved splint in maxillofacial surgery]. We describe a prefabricated monomaxillary arch, fitted with perpendicular supports with a main bar which provides dento-maxillary setting in the antero-posterior direction and also vertically since it is possible to attach it to the free edge of the teeth... | [
-0.035911351442337036,
-0.014044390060007572,
0.032361529767513275,
0.011522181332111359,
-0.02336377464234829,
0.045392539352178574,
0.015539891086518764,
0.04953104257583618,
-0.0169408917427063,
-0.013194170780479908,
0.06627735495567322,
-0.05873085558414459,
-0.028285736218094826,
-0.... |
PMID:12557 | Microcalorimetric measurements of heat production in human erythrocytes. III. Influence of pH, temperature, glucose concentration, and storage conditions. | Heat production in human erythrocytes has been measured under different conditions of pH, glucose concentration, and temperature. Storage conditions have also been varied. The erythrocytes, which were from healthy subjects, were suspended either in autologous plasma or in phosphate buffer. The heat effect, P, was shown... | Microcalorimetric measurements of heat production in human erythrocytes. III. Influence of pH, temperature, glucose concentration, and storage conditions. Heat production in human erythrocytes has been measured under different conditions of pH, glucose concentration, and temperature. Storage conditions have also been v... | [
-0.024942385032773018,
0.054889943450689316,
0.042426519095897675,
0.03454825282096863,
0.03086615353822708,
-0.008023399859666824,
0.045705925673246384,
0.04385841265320778,
-0.04156292974948883,
-0.003795415163040161,
0.02267058938741684,
-0.08995276689529419,
-0.01980813778936863,
0.051... |
PMID:12558 | The absorption of acetylsalicylic acid from the stomach in relation to intragastric pH. | A comparative study on the effect of a buffered (pH 6.5) and an unbuffered (pH 2.9) solution of acetylsalicylic acid (ASA) on gastric pH, gastric emptying, and gastric absorption of ASA was performed in 10 healthy volunteers. Gastric pH was recorded using radiotelemetry. Gastric emptying and gastric absorption was stud... | The absorption of acetylsalicylic acid from the stomach in relation to intragastric pH. A comparative study on the effect of a buffered (pH 6.5) and an unbuffered (pH 2.9) solution of acetylsalicylic acid (ASA) on gastric pH, gastric emptying, and gastric absorption of ASA was performed in 10 healthy volunteers. Gastri... | [
-0.02394883707165718,
-0.023129902780056,
-0.039161715656518936,
0.03200197219848633,
0.025952352210879326,
-0.013512449339032173,
0.03617158904671669,
0.05526801943778992,
-0.020486844703555107,
-0.031133268028497696,
0.05379181355237961,
-0.11438754200935364,
0.004797087982296944,
0.0473... |
PMID:12561 | [Endocrinological studies in arterial hypertension. Search for phaeochromocytoma]. | Elevated urinary catecholamines and their metabolites are the only findings which confirm the presence of pheochromocytoma. This examination is of particular interest if carried out in urine produced after spontaneous hypertensive episodes. Pharmacologic tests when carried out under standard conditions have proven to b... | [Endocrinological studies in arterial hypertension. Search for phaeochromocytoma]. Elevated urinary catecholamines and their metabolites are the only findings which confirm the presence of pheochromocytoma. This examination is of particular interest if carried out in urine produced after spontaneous hypertensive episod... | [
-0.02489251270890236,
-0.0012670287396758795,
0.026931481435894966,
0.026833126321434975,
0.01818971149623394,
-0.013753611594438553,
0.10651885718107224,
0.018647445365786552,
-0.056546881794929504,
-0.04056113213300705,
0.007947237230837345,
-0.011317904107272625,
-0.007333994843065739,
... |
PMID:12562 | [Paralytic ileus in pheochromocytoma. Possible correlation with an attempt at adrenal phlebography]. | Following adrenal phlebography, obstruction of the large bowel associated with adrenergic crisis was observed in a 60 year old patient with pheochromocytoma. As in other published cases of ileus associated with pheochromocytoma, high urinary catecholamine concentrations were found in our patient and the tumor resected ... | [Paralytic ileus in pheochromocytoma. Possible correlation with an attempt at adrenal phlebography]. Following adrenal phlebography, obstruction of the large bowel associated with adrenergic crisis was observed in a 60 year old patient with pheochromocytoma. As in other published cases of ileus associated with pheochro... | [
-0.02153417468070984,
-0.008940315805375576,
0.007751451339572668,
0.041437484323978424,
0.03521747142076492,
-0.02550540678203106,
0.10127607733011246,
0.023754766210913658,
-0.0589749701321125,
-0.06815937161445618,
-0.010023202747106552,
-0.016615519300103188,
0.027879804372787476,
0.07... |
PMID:12563 | [Pharmacokinetics of two beta blocking drugs: detection of a pharmacogenetic abnormality]. | 10 healthy male volunteers received orally either 100 mg tolamolol or 20 mg bufuralol. These experiments were repeated by intravenous administration of 10 and 5 mg respectively of these two drugs. Plasma levels of the parent drugs and their main metabolite were measured. In one subject, the apparent half-life of elimin... | [Pharmacokinetics of two beta blocking drugs: detection of a pharmacogenetic abnormality]. 10 healthy male volunteers received orally either 100 mg tolamolol or 20 mg bufuralol. These experiments were repeated by intravenous administration of 10 and 5 mg respectively of these two drugs. Plasma levels of the parent drug... | [
-0.05722746253013611,
0.01779351942241192,
-0.012801324017345905,
0.028318209573626518,
0.009283361956477165,
0.023358549922704697,
-0.0028376751579344273,
0.00402691587805748,
-0.0291151013225317,
-0.0868789404630661,
-0.018818724900484085,
-0.012179604731500149,
0.013566955924034119,
0.0... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.